[go: up one dir, main page]

NO20016370L - Respiratorisk syncytialvirus-replikasjonsinhibitorer - Google Patents

Respiratorisk syncytialvirus-replikasjonsinhibitorer

Info

Publication number
NO20016370L
NO20016370L NO20016370A NO20016370A NO20016370L NO 20016370 L NO20016370 L NO 20016370L NO 20016370 A NO20016370 A NO 20016370A NO 20016370 A NO20016370 A NO 20016370A NO 20016370 L NO20016370 L NO 20016370L
Authority
NO
Norway
Prior art keywords
respiratory syncytial
syncytial virus
virus replication
replication inhibitors
inhibitors
Prior art date
Application number
NO20016370A
Other languages
English (en)
Other versions
NO20016370D0 (no
NO321599B1 (no
Inventor
Frans Eduard Janssens
Jean Fernand Armand Lacrampe
Jerome Emile George Guillemont
Marc Gaston Venet
Koenraad Jozef Lodewij Andries
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO20016370D0 publication Critical patent/NO20016370D0/no
Publication of NO20016370L publication Critical patent/NO20016370L/no
Publication of NO321599B1 publication Critical patent/NO321599B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO20016370A 1999-06-28 2001-12-27 Respiratorisk syncytialvirusreplikasjonsinhibitorer NO321599B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99202089 1999-06-28
PCT/EP2000/005677 WO2001000615A1 (en) 1999-06-28 2000-06-20 Respiratory syncytial virus replication inhibitors

Publications (3)

Publication Number Publication Date
NO20016370D0 NO20016370D0 (no) 2001-12-27
NO20016370L true NO20016370L (no) 2001-12-27
NO321599B1 NO321599B1 (no) 2006-06-06

Family

ID=8240374

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20016370A NO321599B1 (no) 1999-06-28 2001-12-27 Respiratorisk syncytialvirusreplikasjonsinhibitorer

Country Status (34)

Country Link
US (2) US7071192B1 (no)
EP (2) EP1400519B1 (no)
JP (1) JP2003503403A (no)
KR (1) KR100731273B1 (no)
CN (1) CN1171887C (no)
AR (1) AR024495A1 (no)
AT (2) ATE259796T1 (no)
AU (1) AU774829B2 (no)
BG (1) BG65373B1 (no)
BR (1) BR0011997A (no)
CA (1) CA2376785A1 (no)
CZ (1) CZ20014573A3 (no)
DE (2) DE60033859T2 (no)
DK (1) DK1196410T3 (no)
EA (1) EA004746B1 (no)
EE (1) EE04592B1 (no)
ES (2) ES2215670T3 (no)
HK (1) HK1045998B (no)
HR (2) HRP20010934A2 (no)
HU (1) HUP0201789A3 (no)
IL (2) IL147328A0 (no)
MX (1) MXPA02000117A (no)
MY (1) MY129810A (no)
NO (1) NO321599B1 (no)
NZ (1) NZ515392A (no)
PL (1) PL200694B1 (no)
PT (1) PT1196410E (no)
SI (1) SI1196410T1 (no)
SK (1) SK18952001A3 (no)
TR (2) TR200500707T2 (no)
TW (1) TWI267513B (no)
UA (1) UA75866C2 (no)
WO (1) WO2001000615A1 (no)
ZA (1) ZA200110473B (no)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495580B1 (en) 1998-01-29 2002-12-17 Viropharma Incorporated Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
IL140862A (en) 1998-07-15 2005-05-17 Teijin Ltd Thiobenzimidazole derivatives and pharmaceutical compositions containing the same
US20040010004A1 (en) 2000-01-17 2004-01-15 Naoki Tsuchiya Benzimidazole derivatives
SI1249450T1 (sl) * 2000-01-17 2008-04-30 Teijin Pharma Ltd Derivati benzimidola kot inhibitorji humane kimaze
US6489338B2 (en) 2000-06-13 2002-12-03 Bristol-Myers Squibb Company Imidazopyridine and imidazopyrimidine antiviral agents
PE20020506A1 (es) 2000-08-22 2002-07-09 Glaxo Group Ltd Derivados de pirazol fusionados como inhibidores de la proteina cinasa
US6506738B1 (en) 2000-09-27 2003-01-14 Bristol-Myers Squibb Company Benzimidazolone antiviral agents
JP2004518651A (ja) 2000-12-15 2004-06-24 グラクソ　グループ　リミテッド 治療用化合物
AU2002239348A1 (en) 2000-12-15 2002-06-24 Glaxo Group Limited Pyrazolopyridine derivatives
US6774134B2 (en) 2000-12-20 2004-08-10 Bristol-Myers Squibb Company Heterocyclic substituted 2-methyl-benzimidazole antiviral agents
AU2002248531A1 (en) 2001-03-08 2002-09-24 Smithkline Beecham Corporation Pyrazolopyriadine derivatives
WO2002078700A1 (en) 2001-03-30 2002-10-10 Smithkline Beecham Corporation Pyralopyridines, process for their preparation and use as therapteutic compounds
WO2002083672A1 (en) 2001-04-10 2002-10-24 Smithkline Beecham Corporation Antiviral pyrazolopyridine compounds
AU2002305143A1 (en) 2001-04-27 2002-11-11 Smithkline Beecham Corporation Pyrazolo'1,5-a!pyridine derivatives
US7030150B2 (en) * 2001-05-11 2006-04-18 Trimeris, Inc. Benzimidazole compounds and antiviral uses thereof
EP1401836B1 (en) 2001-06-21 2006-08-23 SmithKline Beecham Corporation Imidazo¬1,2-a|pyridine derivatives for the prophylaxis and treatment of herpes viral infections
ES2262893T3 (es) 2001-10-05 2006-12-01 Smithkline Beecham Corporation Derivados de imidazo-piridina para su uso en el tratamiento de infeccion virica por herpes.
US6919331B2 (en) 2001-12-10 2005-07-19 Bristol-Myers Squibb Company Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents
US7199120B2 (en) 2001-12-11 2007-04-03 Smithkline Beecham Corporation Pyrazolo-pyridine derivatives as antiherpes agents
US7244847B2 (en) * 2002-02-06 2007-07-17 Isis Pharmaceuticals, Inc. Benzimidazole compounds
CA2495266A1 (en) 2002-08-09 2004-02-19 Viropharma Incorporated Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
AU2003258177A1 (en) 2002-08-09 2004-02-25 Viropharma Incorporated Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
WO2004033454A1 (en) 2002-10-03 2004-04-22 Smithkline Beecham Corporation Therapeutic compounds based on pyrazolopyridine derivatives
JP4537407B2 (ja) 2003-10-30 2010-09-01 ベーリンガー インゲルハイム （カナダ） リミテッド Ｒｓｖポリメラーゼインヒビター
AR046959A1 (es) * 2003-12-18 2006-01-04 Tibotec Pharm Ltd Morfolinilo que contiene bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio
WO2005058869A1 (en) * 2003-12-18 2005-06-30 Tibotec Pharmaceuticals Ltd. Aminobenzimidazoles and benzimidazoles as inhibitors of respiratory syncytial virus replication
RU2332414C2 (ru) * 2003-12-18 2008-08-27 Тиботек Фармасьютикалз Лтд. Производные аминобензимидазолов в качестве ингибиторов репликации респираторного синцитиального вируса
AR046972A1 (es) * 2003-12-18 2006-01-04 Tibotec Pharm Ltd Derivados de los amino-bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio
HRP20110313T1 (hr) * 2003-12-18 2011-05-31 Tibotec Pharmaceuticals 5-ili 6-supstituirani derivati benzimidazola kao inhibitori respiratorne sincitijalne virusne replikacije
ATE501135T1 (de) * 2003-12-18 2011-03-15 Tibotec Pharm Ltd Piperidinamino-benzimidazol-derivate al respiratorisches syncytialvirus replikation inhibitoren
EP1951704B1 (en) * 2005-03-17 2016-03-16 Janssen Sciences Ireland UC 1,3-dihydro-benzimidazol-2-ylidene amines useful for the treatment or prevention of viral infections
RU2441866C2 (ru) * 2005-06-20 2012-02-10 Тиботек Фармасьютикалз Лтд 2-замещенные бензимидазолы
AU2006260969B2 (en) 2005-06-20 2011-11-17 Janssen Sciences Ireland Uc 1- ( 2-amino-3- (substituted alkyl)-3H-benzimidazolylmethyl) -3-substituted-1,3-dihydro-benzoimidazol-2-ones with activity on respiratory syncytial virus
RU2419613C2 (ru) * 2005-06-20 2011-05-27 Тиботек Фармасьютикалз Лтд Гетероциклиламиноалкилзамещенные бензимидазолы
CL2008001003A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
WO2010045276A2 (en) * 2008-10-16 2010-04-22 Cara Therapeutics, Inc. Azabenzimidazolones
JP5487692B2 (ja) 2009-04-10 2014-05-07 国立大学法人京都大学 複素環骨格を有する化合物および該化合物を不斉触媒として用いる光学活性化合物の製造方法
MX336687B (es) * 2009-06-30 2016-01-28 Siga Technologies Inc Tratamiento y prevencion de infecciones del virus del dengue.
US8993604B2 (en) 2009-06-30 2015-03-31 Siga Technologies, Inc. Treatment and prevention of dengue virus infections
WO2013011932A1 (ja) 2011-07-15 2013-01-24 塩野義製薬株式会社 Ａｍｐｋ活性化作用を有するアザベンズイミダゾール誘導体
NZ704666A (en) 2012-08-23 2018-05-25 Alios Biopharma Inc Compounds for the treatment of paramoxyvirus viral infections
JP2016079168A (ja) 2014-10-17 2016-05-16 塩野義製薬株式会社 ９員縮合環誘導体

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1140119A (en) * 1978-04-03 1983-01-25 Joseph Torremans N-heterocyclyl-4-piperidinamines
US4556660A (en) 1982-07-12 1985-12-03 Janssen Pharmaceutica N.V. N-(Bicyclic heterocyclyl)-4-piperidinamines
US4634704A (en) 1983-10-06 1987-01-06 Janssen Pharmaceutica, N.V. Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines
US4695569A (en) 1983-11-30 1987-09-22 Janssen Pharmaceutica N.V. Bicyclic heterocyclyl containing N-(bicyclic heterocyclyl)-4-piperidinamines
EP0144101B1 (en) 1983-11-30 1991-02-06 Janssen Pharmaceutica N.V. Bicyclic heterocyclyl containing n-(bicyclic heterocyclyl)-4-piperidinamines
US4588722A (en) 1984-01-09 1986-05-13 Janssen Pharmaceutica N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives
PH23995A (en) 1984-01-09 1990-02-09 Janssen Pharmaceutica Nv 4((bicycle heterocyclyl)-methyl and hetero)piperidines
ATE79620T1 (de) 1986-02-03 1992-09-15 Janssen Pharmaceutica Nv N-heterozyklische-4-piperidinamine enthaltende anti-histaminische zusammensetzungen.
US4897401A (en) 1987-06-19 1990-01-30 Janssen Pharmaceutical N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives useful in treating allergic diseases
CA1317939C (en) * 1987-07-01 1993-05-18 Janssen Pharmaceutica Naamloze Vennootschap ¬(bicyclic heterocyclyl)methyl and -hetero| substituted hexahydro-1h-azepines and pyrrolidines
GB8716313D0 (en) * 1987-07-10 1987-08-19 Janssen Pharmaceutica Nv 2-(heterocyclylalkyl)imidazopyridines
US5597824A (en) 1987-11-03 1997-01-28 Abbott Laboratories Analogs of oxetanyl purines and pyrimidines
IE904378A1 (en) 1989-12-20 1991-07-03 Abbott Lab Analogs of oxetanyl purines and pyrimidines
KR100190299B1 (ko) 1990-07-19 1999-06-01 디르크 반테 신규한 옥사졸릴 유도체
NZ238863A (en) * 1990-07-19 1993-03-26 Janssen Pharmaceutica Nv Substituted thiazolyl and pyridinyl derivatives
US5567824A (en) 1994-05-24 1996-10-22 Merck & Co., Inc. Palladium catalyzed ring closure of triazolyltryptamine
US5693661A (en) * 1995-06-07 1997-12-02 Eli Lilly And Company Anti-viral compounds
PE107598A1 (es) * 1996-09-11 1999-01-29 Ucb Sa Cetirizina util para el tratamiento de enfermedades de tipo virico
WO1998031363A1 (en) * 1997-01-22 1998-07-23 Eli Lilly And Company Anti-viral compounds
EP1001767A4 (en) * 1997-06-04 2001-07-04 Lilly Co Eli ANTIVIRAL CONNECTIONS
HUP0101048A2 (hu) * 1998-03-06 2001-10-28 Janssen Pharmaceutica N.V. Glicin transzport gátló hatású 4,4 bisz[(4-fluorfenil)butil]-1-(piperazinil és piperidinil)-származékok és gyógyászati alkalmazásuk
JP2002521334A (ja) 1998-07-20 2002-07-16 ブリストルーマイヤーズ スクイブ カンパニー 置換ベンズイミダゾール抗ウィルス剤

Also Published As

Publication number Publication date
SK18952001A3 (sk) 2002-11-06
AU774829B2 (en) 2004-07-08
TWI267513B (en) 2006-12-01
CN1171887C (zh) 2004-10-20
HRP20010934A2 (en) 2003-06-30
JP2003503403A (ja) 2003-01-28
NO20016370D0 (no) 2001-12-27
IL147328A0 (en) 2002-08-14
DK1196410T3 (da) 2004-06-28
TR200103805T2 (tr) 2002-06-21
DE60033859D1 (de) 2007-04-19
AR024495A1 (es) 2002-10-02
ATE356121T1 (de) 2007-03-15
AU5222200A (en) 2001-01-31
WO2001000615A8 (en) 2002-01-10
SI1196410T1 (en) 2004-08-31
CN1358182A (zh) 2002-07-10
MY129810A (en) 2007-05-31
EP1196410A1 (en) 2002-04-17
EA004746B1 (ru) 2004-08-26
HK1045998B (zh) 2005-06-03
US7071192B1 (en) 2006-07-04
PT1196410E (pt) 2004-07-30
PL352385A1 (en) 2003-08-25
KR20020000815A (ko) 2002-01-05
HRP20080390A2 (en) 2008-12-31
US7407969B2 (en) 2008-08-05
BR0011997A (pt) 2002-03-05
ES2283716T3 (es) 2007-11-01
IL147328A (en) 2007-06-03
HUP0201789A2 (hu) 2002-11-28
US20060058309A1 (en) 2006-03-16
EE200100694A (et) 2003-02-17
EP1400519B1 (en) 2007-03-07
CZ20014573A3 (cs) 2002-05-15
DE60008382D1 (en) 2004-03-25
NZ515392A (en) 2004-03-26
EP1400519A1 (en) 2004-03-24
EE04592B1 (et) 2006-02-15
ATE259796T1 (de) 2004-03-15
KR100731273B1 (ko) 2007-06-21
EA200200086A1 (ru) 2002-06-27
CA2376785A1 (en) 2001-01-04
DE60033859T2 (de) 2007-11-08
DE60008382T2 (de) 2004-12-02
HUP0201789A3 (en) 2003-12-29
BG65373B1 (bg) 2008-04-30
ES2215670T3 (es) 2004-10-16
BG106288A (en) 2002-10-31
ZA200110473B (en) 2003-03-20
WO2001000615A1 (en) 2001-01-04
PL200694B1 (pl) 2009-01-30
TR200500707T2 (tr) 2005-04-21
EP1196410B1 (en) 2004-02-18
UA75866C2 (en) 2006-06-15
NO321599B1 (no) 2006-06-06
MXPA02000117A (es) 2002-07-02
HK1045998A1 (en) 2002-12-20

Similar Documents

Publication Publication Date Title
NO20016368D0 (no) Respiratorisk syncytialvirus-replikasjonsinhibitorer
NO20016369D0 (no) Respiratorisk syncytialvirus-replikasjonsinhibitorer
NO20016370D0 (no) Respiratorisk syncytialvirus-replikasjonsinhibitorer
NO20022922D0 (no) Inhalasjonsanordning
ATE540013T1 (de) Naphthalinderivate
NO20022921D0 (no) Inhalasjonsanordning
ZA200110478B (en) Respiratory syncytial virus replication inhibitors.
ES1046532Y (es) Inhalador perfeccionado
FR2816398B3 (fr) Fronde perfectionnee
ES1047576Y (es) Nebulizador perfeccionado.
DE60026702D1 (de) Beatmungssystem
ES1046387Y (es) Rodapie perfeccionado
ES1047372Y (es) Pararrayos perfeccionado
IT1314780B1 (it) Fucile perfezionato
IT1315765B1 (it) Guard-rail perfezionato.
DK1267974T3 (da) Inhalationsapparat
ES1048047Y (es) Hucha perfeccionada.
ES1046917Y (es) Perchero perfeccionado.