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NO20015062L - Substituerte 3-cyano-[1.7],[1.5]og[1.8]-naftyridin- inhibitorer for tyrosin-kinaser - Google Patents

Substituerte 3-cyano-[1.7],[1.5]og[1.8]-naftyridin- inhibitorer for tyrosin-kinaser

Info

Publication number
NO20015062L
NO20015062L NO20015062A NO20015062A NO20015062L NO 20015062 L NO20015062 L NO 20015062L NO 20015062 A NO20015062 A NO 20015062A NO 20015062 A NO20015062 A NO 20015062A NO 20015062 L NO20015062 L NO 20015062L
Authority
NO
Norway
Prior art keywords
naphthyridine
cyano
inhibitors
substituted
tyrosine kinases
Prior art date
Application number
NO20015062A
Other languages
English (en)
Other versions
NO20015062D0 (no
Inventor
Allan Wissner
Philip Ross Hamann
Ayako Yamashita
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of NO20015062D0 publication Critical patent/NO20015062D0/no
Publication of NO20015062L publication Critical patent/NO20015062L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20015062A 1999-04-21 2001-10-18 Substituerte 3-cyano-[1.7],[1.5]og[1.8]-naftyridin- inhibitorer for tyrosin-kinaser NO20015062L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29550799A 1999-04-21 1999-04-21
PCT/US2000/010250 WO2000066583A1 (en) 1999-04-21 2000-04-18 Substituted 3-cyano-[1.7], [1.5], and [1.8]-naphthyridine inhibitors of tyrosine kinases

Publications (2)

Publication Number Publication Date
NO20015062D0 NO20015062D0 (no) 2001-10-18
NO20015062L true NO20015062L (no) 2001-10-18

Family

ID=23138006

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20015062A NO20015062L (no) 1999-04-21 2001-10-18 Substituerte 3-cyano-[1.7],[1.5]og[1.8]-naftyridin- inhibitorer for tyrosin-kinaser

Country Status (23)

Country Link
EP (1) EP1171440B1 (no)
JP (1) JP2002543198A (no)
KR (1) KR20020002433A (no)
CN (1) CN100408576C (no)
AR (1) AR029880A1 (no)
AT (1) ATE264328T1 (no)
AU (1) AU776962B2 (no)
BR (1) BR0009870A (no)
CA (1) CA2365212A1 (no)
CZ (1) CZ20013660A3 (no)
DE (1) DE60009888T2 (no)
DK (1) DK1171440T3 (no)
ES (1) ES2216884T3 (no)
HK (1) HK1040077B (no)
HU (1) HUP0200816A3 (no)
IL (1) IL145870A0 (no)
NO (1) NO20015062L (no)
NZ (1) NZ514576A (no)
PL (1) PL350920A1 (no)
PT (1) PT1171440E (no)
RU (1) RU2001131356A (no)
WO (1) WO2000066583A1 (no)
ZA (1) ZA200108015B (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2003002287A1 (es) * 2002-11-25 2005-01-14 Wyeth Corp COMPUESTOS DERIVADOS DE TIENO[3,2-b]-PIRIDINA-6-CARBONITRILOS Y TIENEO[2,3-b]-PIRIDINA-5-CARBONITRILOS, COMPOSICION FARMACEUTICA, PROCEDIMIENTO DE PREPARACION Y COMPUESTOS INTERMEDIARIOS, Y SU USO EN EL TRATAMIENTO DEL CANCER, APOPLEJIA, OSTEOPOROSIS
US7276519B2 (en) 2002-11-25 2007-10-02 Wyeth Thieno[3,2-b]pyridine-6-carbonitriles and thieno[2,3-b]pyridine-5-carbonitriles as protein kinase inhibitors
US7135575B2 (en) 2003-03-03 2006-11-14 Array Biopharma, Inc. P38 inhibitors and methods of use thereof
NZ588139A (en) 2004-04-08 2012-02-24 Targegen Inc 7-Aryl-3-arylamino-benzo[1,2,4]triazine derivatives
EP1881981A1 (en) * 2005-05-18 2008-01-30 Wyeth 4, 6-diamino-[1,7] naphthyridine-3-carbonitrile inhibitors of tpl2 kinase and methods of making and using the same
KR101467723B1 (ko) 2005-11-01 2014-12-03 탈자진 인코포레이티드 키나제의 비-아릴 메타-피리미딘 억제제
WO2007089646A1 (en) 2006-01-31 2007-08-09 Array Biopharma Inc. Kinase inhibitors and methods of use thereof
ES2301380B1 (es) 2006-08-09 2009-06-08 Laboratorios Almirall S.A. Nuevos derivados de 1,7-naftiridina.
ES2320955B1 (es) 2007-03-02 2010-03-16 Laboratorios Almirall S.A. Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida.
ES2329639B1 (es) 2007-04-26 2010-09-23 Laboratorios Almirall S.A. Nuevos derivados de 4,8-difenilpoliazanaftaleno.
EP2108641A1 (en) 2008-04-11 2009-10-14 Laboratorios Almirall, S.A. New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors
EP2113503A1 (en) 2008-04-28 2009-11-04 Laboratorios Almirall, S.A. New substituted indolin-2-one derivatives and their use as p39 mitogen-activated kinase inhibitors
CN102625799A (zh) * 2009-06-25 2012-08-01 安姆根有限公司 杂环化合物及其用途
EP2332939A1 (en) 2009-11-26 2011-06-15 Æterna Zentaris GmbH Novel Naphthyridine derivatives and the use thereof as kinase inhibitors
CA2816957A1 (en) 2010-11-07 2012-05-10 Targegen, Inc. Compositions and methods for treating myelofibrosis
CN102675311A (zh) * 2011-06-14 2012-09-19 苏春华 一种氟代丙烯酰胺的衍生物
CA2863132A1 (en) * 2012-01-30 2013-08-08 F. Hoffmann-La Roche Ag Isoquinoline and naphthyridine derivatives
UY35772A (es) 2013-10-14 2015-05-29 Bayer Cropscience Ag Nuevos compuestos plaguicidas
SG11201805286RA (en) * 2015-12-24 2018-07-30 Kyowa Hakko Kirin Co Ltd α,β-UNSATURATED AMIDE COMPOUND
CN107556309B (zh) * 2017-09-11 2020-12-01 浙江永宁药业股份有限公司 多取代四氢萘啶类化合物的药物用途及其制备方法
CN108299429B (zh) * 2018-04-09 2021-10-08 中南大学 一类八氢苯并萘啶化合物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9312891D0 (en) * 1993-06-22 1993-08-04 Boots Co Plc Therapeutic agents
EP0929526B1 (en) * 1996-09-25 2005-07-27 AstraZeneca AB Qinoline derivatives inhibiting the effect of growth factors such as vegf
UA73073C2 (uk) * 1997-04-03 2005-06-15 Уайт Холдінгз Корпорейшн Заміщені 3-ціанохіноліни, спосіб їх одержання та фармацевтична композиція
TW436485B (en) * 1997-08-01 2001-05-28 American Cyanamid Co Substituted quinazoline derivatives

Also Published As

Publication number Publication date
IL145870A0 (en) 2002-07-25
JP2002543198A (ja) 2002-12-17
AU4463900A (en) 2000-11-17
HK1040077A1 (en) 2002-05-24
HUP0200816A3 (en) 2003-06-30
CN100408576C (zh) 2008-08-06
WO2000066583A1 (en) 2000-11-09
HK1040077B (en) 2004-09-10
EP1171440A1 (en) 2002-01-16
ZA200108015B (en) 2003-03-26
NO20015062D0 (no) 2001-10-18
KR20020002433A (ko) 2002-01-09
RU2001131356A (ru) 2003-06-27
DE60009888T2 (de) 2005-04-21
PT1171440E (pt) 2004-07-30
EP1171440B1 (en) 2004-04-14
PL350920A1 (en) 2003-02-10
HUP0200816A2 (en) 2002-08-28
ES2216884T3 (es) 2004-11-01
DK1171440T3 (da) 2004-08-02
CZ20013660A3 (cs) 2002-01-16
DE60009888D1 (de) 2004-05-19
CA2365212A1 (en) 2000-11-09
BR0009870A (pt) 2002-01-08
AR029880A1 (es) 2003-07-23
AU776962B2 (en) 2004-09-30
NZ514576A (en) 2004-02-27
ATE264328T1 (de) 2004-04-15
CN1347416A (zh) 2002-05-01

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