NO20014364L - Ny cytokin-zalphall-ligand - Google Patents
Ny cytokin-zalphall-ligandInfo
- Publication number
- NO20014364L NO20014364L NO20014364A NO20014364A NO20014364L NO 20014364 L NO20014364 L NO 20014364L NO 20014364 A NO20014364 A NO 20014364A NO 20014364 A NO20014364 A NO 20014364A NO 20014364 L NO20014364 L NO 20014364L
- Authority
- NO
- Norway
- Prior art keywords
- polypeptide
- zalpha11 ligand
- new cytokine
- cytokine zalpha11
- seq
- Prior art date
Links
- 102000004127 Cytokines Human genes 0.000 title 1
- 108090000695 Cytokines Proteins 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- External Artificial Organs (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26490899A | 1999-03-09 | 1999-03-09 | |
| US26599299A | 1999-03-11 | 1999-03-11 | |
| US14201399P | 1999-07-01 | 1999-07-01 | |
| PCT/US2000/006067 WO2000053761A2 (en) | 1999-03-09 | 2000-03-09 | Human cytokine as ligand of the zalpha receptor and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20014364D0 NO20014364D0 (no) | 2001-09-07 |
| NO20014364L true NO20014364L (no) | 2001-11-09 |
| NO331551B1 NO331551B1 (no) | 2012-01-23 |
Family
ID=27385745
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20014364A NO331551B1 (no) | 1999-03-09 | 2001-09-07 | Isolert cytokin-zalpha11-ligand-polypeptid, isolert polynukleotid, ekspresjonsvektor, dyrket celle, fremgangsmate for fremstilling av peptidet, antistoff som binder til peptidet, anvendelse av preparat omfattende peptidet for fremstilling av medikament for behandling av sykdom, fremgangsmate for pavisning av peptidet i en biologisk prove samt polypeptidet for anvendelse innen medisin |
| NO20111085A NO20111085L (no) | 1999-03-09 | 2011-07-29 | Isolert cytokin-zalphall-ligand-polypeptid, isolert Polynukleotid, ekspresjonsvektor, dyrket celle, fremgangsmate for fremstilling av peptidet, antistoff som binder til peptidet, anvendelse av preparat omfattende peptidet for fremstilling av medikament for behandling av sykdom, fremgangsmate for pavisning av peptidet i en biologisk prove samt polypeptidet for anvendelse innen medisin |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20111085A NO20111085L (no) | 1999-03-09 | 2011-07-29 | Isolert cytokin-zalphall-ligand-polypeptid, isolert Polynukleotid, ekspresjonsvektor, dyrket celle, fremgangsmate for fremstilling av peptidet, antistoff som binder til peptidet, anvendelse av preparat omfattende peptidet for fremstilling av medikament for behandling av sykdom, fremgangsmate for pavisning av peptidet i en biologisk prove samt polypeptidet for anvendelse innen medisin |
Country Status (23)
| Country | Link |
|---|---|
| EP (3) | EP1165791B1 (no) |
| JP (1) | JP4405686B2 (no) |
| KR (1) | KR100743640B1 (no) |
| CN (5) | CN102406937A (no) |
| AT (1) | ATE377076T1 (no) |
| AU (2) | AU777842B2 (no) |
| BR (1) | BR0008772B1 (no) |
| CA (1) | CA2366921C (no) |
| CZ (1) | CZ302921B6 (no) |
| DE (1) | DE60036930T2 (no) |
| DK (1) | DK1165791T3 (no) |
| ES (1) | ES2295019T3 (no) |
| HU (1) | HU229148B1 (no) |
| IL (5) | IL145288A0 (no) |
| MX (1) | MXPA01009074A (no) |
| NO (2) | NO331551B1 (no) |
| NZ (1) | NZ514708A (no) |
| PL (1) | PL207350B1 (no) |
| PT (1) | PT1165791E (no) |
| RU (1) | RU2346951C2 (no) |
| UA (1) | UA84387C2 (no) |
| WO (1) | WO2000053761A2 (no) |
| ZA (1) | ZA017370B (no) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6057128A (en) | 1998-03-17 | 2000-05-02 | Genetics Institute, Inc. | MU-1, member of the cytokine receptor family |
| US7198789B2 (en) | 1998-03-17 | 2007-04-03 | Genetics Institute, Llc | Methods and compositions for modulating interleukin-21 receptor activity |
| US7189400B2 (en) | 1998-03-17 | 2007-03-13 | Genetics Institute, Llc | Methods of treatment with antagonists of MU-1 |
| KR100743640B1 (ko) * | 1999-03-09 | 2007-07-27 | 지모제넥틱스, 인코포레이티드 | 신규한 사이토킨 zalpha 11 리간드 |
| WO2003028630A2 (en) * | 2001-10-04 | 2003-04-10 | Genetics Institute Llc. | Methods and compositions for modulating interleukin-21 receptor activity |
| EP2130919A1 (en) * | 2001-11-05 | 2009-12-09 | ZymoGenetics, Inc. | IL-21 antagonists |
| PT1531850E (pt) * | 2002-06-07 | 2012-05-07 | Zymogenetics Inc | Utilização de il-21 e anticorpo monoclonal para tratar cancros sólidos |
| MXPA05000655A (es) | 2002-07-15 | 2006-02-22 | Harvard College | Metodos y composiciones para modular el desarrollo y la funcion de las celulas t helper (th). |
| KR20050065590A (ko) * | 2002-10-11 | 2005-06-29 | 노보 노르디스크 에이/에스 | Il 21을 이용한 알레르기 상태의 치료법 |
| MXPA05003729A (es) * | 2002-10-11 | 2005-06-17 | Novo Nordisk As | Tratamiento de condiciones alergicas mediante el uso de il 21. |
| RU2354703C2 (ru) * | 2002-12-13 | 2009-05-10 | Займодженетикс, Инк. | Продуцирование il-21 в прокариотических клетках-хозяевах |
| EP2184298A1 (en) * | 2003-03-14 | 2010-05-12 | Wyeth a Corporation of the State of Delaware | Antibodies against human IL-21 receptor and uses therefor |
| CA2529520A1 (en) * | 2003-06-19 | 2004-12-29 | Centocor, Inc. | Interleukin-21 analogs |
| DK1648931T3 (da) * | 2003-07-21 | 2011-03-07 | Transgene Sa | Multifunktionelle cytokiner |
| DE602004031341D1 (de) | 2003-07-21 | 2011-03-24 | Transgene Sa | Multifunktionelle cytokine |
| AU2004275871A1 (en) * | 2003-09-25 | 2005-04-07 | Zymogenetics, Inc. | Methods of treating autoimmune diseases using IL-21 |
| US20060228331A1 (en) | 2003-10-10 | 2006-10-12 | Novo Nordisk A/S | IL-21 Derivatives and variants |
| WO2005035565A1 (en) * | 2003-10-10 | 2005-04-21 | Novo Nordisk A/S | Il-21 derivatives |
| EP2641611A3 (en) | 2003-10-17 | 2013-12-18 | Novo Nordisk A/S | Combination therapy |
| WO2005067956A2 (en) * | 2004-01-15 | 2005-07-28 | Novo Nordisk A/S | Use of interleukin-21 for the treatment of autoimune diseases and allograft rejection |
| ES2642214T3 (es) | 2004-01-21 | 2017-11-15 | Novo Nordisk Health Care Ag | Conjugación de péptidos mediante transglutaminasa |
| GT200600148A (es) | 2005-04-14 | 2006-11-22 | Metodos para el tratamiento y la prevencion de fibrosis | |
| WO2006111524A2 (en) | 2005-04-18 | 2006-10-26 | Novo Nordisk A/S | Il-21 variants |
| JP5322653B2 (ja) * | 2005-11-28 | 2013-10-23 | ザイモジェネティクス, インコーポレイテッド | Il−21アンタゴニスト |
| WO2008049920A2 (en) | 2006-10-26 | 2008-05-02 | Novo Nordisk A/S | Il-21 variants |
| WO2008074863A1 (en) | 2006-12-21 | 2008-06-26 | Novo Nordisk A/S | Interleukin-21 variants with altered binding to the il-21 receptor |
| RU2504552C2 (ru) | 2007-12-07 | 2014-01-20 | Займодженетикс, Инк. | Моноклональные антитела против il-21 человека |
| JP2011520989A (ja) | 2008-05-23 | 2011-07-21 | ワイス・エルエルシー | インターロイキン−21受容体の結合性タンパク質を利用する治療法 |
| AR071885A1 (es) | 2008-05-23 | 2010-07-21 | Wyeth Corp | Proteinas de union al receptor de interleuquina 21 |
| US20100075329A1 (en) | 2008-09-23 | 2010-03-25 | O'toole Margot | Methods for predicting production of activating signals by cross-linked binding proteins |
| CN102021196B (zh) * | 2009-11-20 | 2013-06-26 | 上海杰隆生物工程股份有限公司 | 毕赤酵母生产重组人白细胞介素21的方法 |
| JP6464081B2 (ja) | 2012-06-27 | 2019-02-06 | ラトガース,ザ ステート ユニバーシティ オブ ニュー ジャージー | フローサイトメトリーを用いたrna測定によるt細胞活性化のための迅速アッセイ |
| WO2015110930A1 (en) | 2014-01-24 | 2015-07-30 | Pfizer Inc. | Modified interleukin 21 receptor proteins |
| EP2982693A1 (en) * | 2014-08-07 | 2016-02-10 | Affimed Therapeutics AG | CD3 binding domain |
| WO2021231923A1 (en) * | 2020-05-14 | 2021-11-18 | Metaclipse Therapeutics Corporation | Compositions and methods for detecting and treating a sars-cov-2 infection |
| US12012441B2 (en) | 2020-10-26 | 2024-06-18 | Neptune Biosciences Llc | Engineered human IL-21 cytokines and methods for using the same |
| CN112662694A (zh) * | 2020-12-25 | 2021-04-16 | 康九生物科技(长春)有限公司 | 一种麦芽糖结合蛋白、麦芽糖结合蛋白表达载体、重组工程菌及其应用 |
| JP2024536840A (ja) * | 2021-09-26 | 2024-10-08 | ウーシー バイオロジクス アイルランド リミテッド | Il-2バリアント及びその融合タンパク質 |
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2000
- 2000-03-09 KR KR1020017011499A patent/KR100743640B1/ko not_active Expired - Fee Related
- 2000-03-09 HU HU0200418A patent/HU229148B1/hu not_active IP Right Cessation
- 2000-03-09 CN CN2011103037822A patent/CN102406937A/zh active Pending
- 2000-03-09 CN CNA2005101141968A patent/CN1827639A/zh active Pending
- 2000-03-09 CN CN2006101031515A patent/CN1927883B/zh not_active Expired - Fee Related
- 2000-03-09 EP EP00916164A patent/EP1165791B1/en not_active Expired - Lifetime
- 2000-03-09 CN CNB008068747A patent/CN100500846C/zh not_active Expired - Fee Related
- 2000-03-09 PL PL351160A patent/PL207350B1/pl unknown
- 2000-03-09 CZ CZ20013184A patent/CZ302921B6/cs not_active IP Right Cessation
- 2000-03-09 DK DK00916164T patent/DK1165791T3/da active
- 2000-03-09 EP EP20100185147 patent/EP2295577A3/en not_active Withdrawn
- 2000-03-09 MX MXPA01009074A patent/MXPA01009074A/es active IP Right Grant
- 2000-03-09 AU AU37312/00A patent/AU777842B2/en not_active Ceased
- 2000-03-09 RU RU2004126135/13A patent/RU2346951C2/ru not_active IP Right Cessation
- 2000-03-09 IL IL14528800A patent/IL145288A0/xx unknown
- 2000-03-09 PT PT00916164T patent/PT1165791E/pt unknown
- 2000-03-09 WO PCT/US2000/006067 patent/WO2000053761A2/en not_active Ceased
- 2000-03-09 DE DE60036930T patent/DE60036930T2/de not_active Expired - Lifetime
- 2000-03-09 JP JP2000603382A patent/JP4405686B2/ja not_active Expired - Fee Related
- 2000-03-09 ES ES00916164T patent/ES2295019T3/es not_active Expired - Lifetime
- 2000-03-09 EP EP07017344A patent/EP1881070B1/en not_active Expired - Lifetime
- 2000-03-09 CA CA2366921A patent/CA2366921C/en not_active Expired - Fee Related
- 2000-03-09 UA UA2001106769A patent/UA84387C2/ru unknown
- 2000-03-09 AT AT00916164T patent/ATE377076T1/de active
- 2000-03-09 NZ NZ514708A patent/NZ514708A/en not_active IP Right Cessation
- 2000-03-09 CN CN2009101354816A patent/CN101575377B/zh not_active Expired - Fee Related
- 2000-03-09 BR BRPI0008772-6A patent/BR0008772B1/pt not_active IP Right Cessation
-
2001
- 2001-09-05 IL IL145288A patent/IL145288A/en not_active IP Right Cessation
- 2001-09-06 ZA ZA2001/07370A patent/ZA017370B/en unknown
- 2001-09-07 NO NO20014364A patent/NO331551B1/no not_active IP Right Cessation
-
2005
- 2005-01-20 AU AU2005200240A patent/AU2005200240A1/en not_active Abandoned
-
2008
- 2008-12-04 IL IL195713A patent/IL195713A/en not_active IP Right Cessation
-
2010
- 2010-08-04 IL IL207403A patent/IL207403A/en not_active IP Right Cessation
- 2010-08-05 IL IL207424A patent/IL207424A/en not_active IP Right Cessation
-
2011
- 2011-07-29 NO NO20111085A patent/NO20111085L/no unknown
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