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NO20014783L - DNA sequence encoding interleukin-1 inhibitors and method of preparing the compounds - Google Patents

DNA sequence encoding interleukin-1 inhibitors and method of preparing the compounds

Info

Publication number
NO20014783L
NO20014783L NO20014783A NO20014783A NO20014783L NO 20014783 L NO20014783 L NO 20014783L NO 20014783 A NO20014783 A NO 20014783A NO 20014783 A NO20014783 A NO 20014783A NO 20014783 L NO20014783 L NO 20014783L
Authority
NO
Norway
Prior art keywords
inhibitors
preparing
compounds
sequence encoding
dna sequence
Prior art date
Application number
NO20014783A
Other languages
Norwegian (no)
Other versions
NO316917B1 (en
NO20014783D0 (en
Inventor
Charles H Hannon
Stephen P Eisenberg
Robert C Thompson
William P Arend
Fenneke G Joslin
Andreas Sommer
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO20014783L publication Critical patent/NO20014783L/en
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of NO20014783D0 publication Critical patent/NO20014783D0/en
Publication of NO316917B1 publication Critical patent/NO316917B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO20014783A 1988-05-27 2001-10-01 Process for the preparation of a pharmaceutical composition containing an interleukin-1 inhibitor NO316917B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US19991588A 1988-05-27 1988-05-27
US23871388A 1988-08-31 1988-08-31
US26653188A 1988-11-03 1988-11-03
PCT/US1989/002275 WO1989011540A1 (en) 1988-05-27 1989-05-25 Interleukin-1 inhibitors

Publications (3)

Publication Number Publication Date
NO20014783L true NO20014783L (en) 1991-01-28
NO20014783D0 NO20014783D0 (en) 2001-10-01
NO316917B1 NO316917B1 (en) 2004-06-21

Family

ID=27394086

Family Applications (2)

Application Number Title Priority Date Filing Date
NO19905090A NO316122B1 (en) 1988-05-27 1990-11-23 DNA sequence encoding interleukin-1 inhibitors, recombinant vector containing and capable of encoding the DNA sequence, host cell containing and can express vectors, and method for producing interleukin-1 inhibitors, and recombinant host cell s.
NO20014783A NO316917B1 (en) 1988-05-27 2001-10-01 Process for the preparation of a pharmaceutical composition containing an interleukin-1 inhibitor

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO19905090A NO316122B1 (en) 1988-05-27 1990-11-23 DNA sequence encoding interleukin-1 inhibitors, recombinant vector containing and capable of encoding the DNA sequence, host cell containing and can express vectors, and method for producing interleukin-1 inhibitors, and recombinant host cell s.

Country Status (9)

Country Link
JP (2) JP3192651B2 (en)
KR (1) KR970002917B1 (en)
BR (1) BR8907457A (en)
DK (1) DK172763B1 (en)
FI (2) FI109206B (en)
HU (3) HU9803037D0 (en)
NO (2) NO316122B1 (en)
OA (1) OA09631A (en)
WO (1) WO1989011540A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6858409B1 (en) 1988-05-27 2005-02-22 Amgen Inc. Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors
US5075222A (en) 1988-05-27 1991-12-24 Synergen, Inc. Interleukin-1 inhibitors
US6159460A (en) * 1988-05-27 2000-12-12 Amgen Inc. Method for treating interleukin-1 mediated diseases
US5872095A (en) * 1990-05-01 1999-02-16 Chiron Corporation IL-1 receptor antagonists medicaments
ATE178094T1 (en) * 1990-05-01 1999-04-15 Chiron Corp INTERLEUKIN-I ANTAGONIST AND ITS USE
US5747444A (en) * 1990-10-09 1998-05-05 Chiron Corporation Method of treating graft-versus-host disease
US5932537A (en) * 1990-10-09 1999-08-03 Chiron Corporation Method for attenuating a cellular response to IL-1
ZA921120B (en) 1991-02-19 1993-01-27 Smithkline Beecham Corp Cytokine inhibitors
US6294170B1 (en) 1997-08-08 2001-09-25 Amgen Inc. Composition and method for treating inflammatory diseases
US20030103978A1 (en) 2000-02-23 2003-06-05 Amgen Inc. Selective binding agents of osteoprotegerin binding protein
PH12012502439A1 (en) 2001-06-26 2013-06-17 Amgen Inc Antibodies to opgl
AU2002346882A1 (en) * 2001-10-26 2003-05-06 Novartis Ag Methods for the treatment of osteoarthritis and compositions thereof
JP4761710B2 (en) 2002-04-05 2011-08-31 アムジェン インコーポレイテッド Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors
US7709611B2 (en) 2004-08-04 2010-05-04 Amgen Inc. Antibodies to Dkk-1
SI2188313T1 (en) 2007-08-21 2018-04-30 Amgen, Inc. Human c-fms antigen binding proteins
WO2010030979A2 (en) * 2008-09-12 2010-03-18 Xbiotech, Inc. Targeting pathogenic monocytes
WO2012025910A1 (en) 2010-08-26 2012-03-01 Centro De Investigación Y De Estudios Avanzados Del Instituto Politécnico Nacional METHODS OF DIAGNOSIS AND TREATMENT OF OSTEOARTHRITIS AT EARLY STAGES USING INTERLEUKIN IL-1ß AS EARLY BIOMARKER OF THE DISEASE
WO2012122985A1 (en) 2011-03-14 2012-09-20 University Of Copenhagen Antagonists of the interleukin- 1 receptor
US20140308294A1 (en) 2011-04-15 2014-10-16 Merck Patent Gmbh Anti-IL-1R1 Inhibitors For Use in Cancer
TW201605896A (en) 2013-08-30 2016-02-16 安美基股份有限公司 GITR antigen binding proteins
WO2015087187A1 (en) 2013-12-10 2015-06-18 Rinat Neuroscience Corp. Anti-sclerostin antibodies
TWI742054B (en) 2016-03-08 2021-10-11 美商健生生物科技公司 Gitr antibodies, methods, and uses

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8820676A (en) * 1987-08-26 1989-07-03 Biogen Inc ORGANIC MATERIALS, METHODS FOR PREPARING ORGANIC MATERIALS AND THE USE OF SUCH MATERIALS IN THERAPY.

Also Published As

Publication number Publication date
WO1989011540A1 (en) 1989-11-30
FI109206B (en) 2002-06-14
FI20020545L (en) 2002-03-21
BR8907457A (en) 1991-04-02
AU3746989A (en) 1989-12-12
JPH03505279A (en) 1991-11-21
NO905090D0 (en) 1990-11-23
FI20020545A7 (en) 2002-03-21
HU9803037D0 (en) 1999-11-29
HU893412D0 (en) 1991-05-28
NO316122B1 (en) 2003-12-15
NO905090L (en) 1991-01-28
HU222810B1 (en) 2003-11-28
NO316917B1 (en) 2004-06-21
KR970002917B1 (en) 1997-03-12
NO20014783D0 (en) 2001-10-01
DK8591D0 (en) 1991-01-18
HU215434B (en) 1999-04-28
OA09631A (en) 1993-04-30
DK172763B1 (en) 1999-07-05
DK8591A (en) 1991-01-18
JP2001029093A (en) 2001-02-06
AU633831B2 (en) 1993-02-11
JP3192651B2 (en) 2001-07-30
FI905812A0 (en) 1990-11-26

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