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NO20013901L - Unsaturated cholesterol derivatives and their use in the preparation of meiosis-regulating drugs - Google Patents

Unsaturated cholesterol derivatives and their use in the preparation of meiosis-regulating drugs

Info

Publication number
NO20013901L
NO20013901L NO20013901A NO20013901A NO20013901L NO 20013901 L NO20013901 L NO 20013901L NO 20013901 A NO20013901 A NO 20013901A NO 20013901 A NO20013901 A NO 20013901A NO 20013901 L NO20013901 L NO 20013901L
Authority
NO
Norway
Prior art keywords
meiosis
cholesterol derivatives
preparation
unsaturated cholesterol
regulating drugs
Prior art date
Application number
NO20013901A
Other languages
Norwegian (no)
Other versions
NO20013901D0 (en
Inventor
Thorsten Blume
Peter Esperling
Joachim Kuhnke
Christa Hegele-Hartung
Monika Lessl
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO20013901D0 publication Critical patent/NO20013901D0/en
Publication of NO20013901L publication Critical patent/NO20013901L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Den foreliggende oppfinnelse angår farmasøytiske aktive umettede kolestanderivater, farmasøytiske sammensetninger omfattende disse som aktive substanser og anvendelse av disse nye forbindelsene for fremstilling av medikamenter. Nærmere bestemt er det blitt funnet at umettede kolestanderivater ifølge oppfinnelsen kan anvendes ved regulering av meiose.The present invention relates to pharmaceutically active unsaturated cholesterol derivatives, pharmaceutical compositions comprising these as active substances and the use of these novel compounds for the manufacture of medicaments. More specifically, it has been found that unsaturated cholesterol derivatives of the invention can be used in the control of meiosis.

NO20013901A 1999-02-10 2001-08-10 Unsaturated cholesterol derivatives and their use in the preparation of meiosis-regulating drugs NO20013901L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99250040 1999-02-10
PCT/EP2000/001074 WO2000047604A1 (en) 1999-02-10 2000-02-09 Unsaturated cholestane derivatives and their use for the preparation of meiosis regulating medicaments

Publications (2)

Publication Number Publication Date
NO20013901D0 NO20013901D0 (en) 2001-08-10
NO20013901L true NO20013901L (en) 2001-08-10

Family

ID=8241140

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013901A NO20013901L (en) 1999-02-10 2001-08-10 Unsaturated cholesterol derivatives and their use in the preparation of meiosis-regulating drugs

Country Status (15)

Country Link
EP (1) EP1150993A1 (en)
JP (1) JP2002536456A (en)
KR (1) KR20010101820A (en)
CN (1) CN1368977A (en)
AU (1) AU3279700A (en)
BR (1) BR0008065A (en)
CA (1) CA2359687A1 (en)
CZ (1) CZ20012866A3 (en)
HU (1) HUP0200280A2 (en)
IL (1) IL143735A0 (en)
NO (1) NO20013901L (en)
PL (1) PL350557A1 (en)
SK (1) SK11382001A3 (en)
WO (1) WO2000047604A1 (en)
ZA (1) ZA200107387B (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716777A (en) * 1994-06-23 1998-02-10 Novo Nordisk A/S Regulation of meiosis using sterols
BR9607673A (en) * 1995-03-06 1998-06-16 Novo Nordisk As Process to stimulate meiosis of a germ cell and use of a compound that causes the accumulation of an endogenous meiosis activating substance
IL122609A0 (en) * 1995-06-23 1998-08-16 Novo Nordisk As Meiosis regulating compounds
EP0946584B1 (en) * 1996-12-20 2003-04-23 Novo Nordisk A/S Meiosis regulating compounds

Also Published As

Publication number Publication date
HUP0200280A2 (en) 2002-07-29
PL350557A1 (en) 2002-12-16
CN1368977A (en) 2002-09-11
ZA200107387B (en) 2002-12-06
WO2000047604A1 (en) 2000-08-17
CZ20012866A3 (en) 2002-01-16
BR0008065A (en) 2001-11-06
CA2359687A1 (en) 2000-08-17
NO20013901D0 (en) 2001-08-10
IL143735A0 (en) 2002-04-21
EP1150993A1 (en) 2001-11-07
KR20010101820A (en) 2001-11-14
JP2002536456A (en) 2002-10-29
SK11382001A3 (en) 2002-01-07
AU3279700A (en) 2000-08-29

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application