NO20013791D0 - Fremgangsmåte for fremstilling av pseudomonsyre A-antibiotika ved hjelp av en mikrobiologisk fremgangsmåte - Google Patents

Fremgangsmåte for fremstilling av pseudomonsyre A-antibiotika ved hjelp av en mikrobiologisk fremgangsmåte

Info

Publication number: NO20013791D0
Authority: NO; Norway
Prior art keywords: antibiotics; preparation; pseudomonic acid; microbiological method; microbiological
Prior art date: 1999-02-03

Application number

NO20013791A

Other languages

English (en)

Other versions

NO20013791L (no

Inventor

Valeria Szell

Ildiko Lang

Istvan Barta

Aniko Tegdes

Karoly Albrecht

Julianna Mozes

Istvan Mihaly Szabo

Magdolna Petroczki

Janos Erdei

Eva Gulyas

Gabor Balogh

Original Assignee

Biogal Gyogyszergyar

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-02-03

Filing date

2001-08-02

Publication date

2001-08-02

2001-08-02 Application filed by Biogal Gyogyszergyar filed Critical Biogal Gyogyszergyar

2001-08-02 Publication of NO20013791D0 publication Critical patent/NO20013791D0/no

2001-10-02 Publication of NO20013791L publication Critical patent/NO20013791L/no

Links

MINDHVHHQZYEEK-UHFFFAOYSA-N (E)-(2S,3R,4R,5S)-5-[(2S,3S,4S,5S)-2,3-epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxy-(beta)-methyl-2H-pyran-2-crotonic acid ester with 9-hydroxynonanoic acid Natural products CC(O)C(C)C1OC1CC1C(O)C(O)C(CC(C)=CC(=O)OCCCCCCCCC(O)=O)OC1 MINDHVHHQZYEEK-UHFFFAOYSA-N 0.000 title 1
239000003242 anti bacterial agent Substances 0.000 title 1
229940088710 antibiotic agent Drugs 0.000 title 1
238000000034 method Methods 0.000 title 1
238000013048 microbiological method Methods 0.000 title 1
MINDHVHHQZYEEK-HBBNESRFSA-N mupirocin Chemical compound C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC(O)=O)OC1 MINDHVHHQZYEEK-HBBNESRFSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
- C12P17/162—Heterorings having oxygen atoms as the only ring heteroatoms, e.g. Lasalocid
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/38—Pseudomonas

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Wood Science & Technology (AREA)
Medicinal Chemistry (AREA)
Genetics & Genomics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biotechnology (AREA)
Virology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Dermatology (AREA)
Tropical Medicine & Parasitology (AREA)
Biomedical Technology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Pulmonology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Materials By Optical Means (AREA)

NO20013791A 1999-02-03 2001-08-02 Fremgangsmåte for fremstilling av pseudomonsyre A-antibiotika ved hjelp av en mikrobiologisk fremgangsmåte NO20013791L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US11845799P	1999-02-03	1999-02-03
US13733499P	1999-06-03	1999-06-03
PCT/US2000/002880 WO2000046389A1 (en)	1999-02-03	2000-02-03	Process for the preparation of pseudomonic acid a antibiotic by microbiological method

Publications (2)

Publication Number	Publication Date
NO20013791D0 true NO20013791D0 (no)	2001-08-02
NO20013791L NO20013791L (no)	2001-10-02

Family

ID=26816383

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20013791A NO20013791L (no)	1999-02-03	2001-08-02	Fremgangsmåte for fremstilling av pseudomonsyre A-antibiotika ved hjelp av en mikrobiologisk fremgangsmåte

Country Status (22)

Country	Link
US (3)	US6509177B1 (no)
EP (1)	EP1151131A4 (no)
JP (1)	JP2003515311A (no)
KR (1)	KR20010113674A (no)
CN (2)	CN1203184C (no)
AU (1)	AU762768B2 (no)
BG (1)	BG105776A (no)
BR (1)	BR0009179A (no)
CA (1)	CA2360865A1 (no)
CZ (1)	CZ20012724A3 (no)
HK (1)	HK1041903A1 (no)
HR (1)	HRP20010576A2 (no)
HU (1)	HUP0300363A2 (no)
IL (2)	IL144679A0 (no)
IS (1)	IS6028A (no)
MX (1)	MXPA01007806A (no)
NO (1)	NO20013791L (no)
PL (1)	PL358615A1 (no)
SK (1)	SK10892001A3 (no)
TR (1)	TR200102234T2 (no)
WO (1)	WO2000046389A1 (no)
YU (1)	YU55601A (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HRP20010576A2 (en)	1999-02-03	2002-08-31	Biogal Gyogyszergyar	Process for the preparation of pseudomonic acid a antibiotic by microbiological method
ES2228294T1 (es)	2001-06-21	2005-04-16	Biogal Gyogyszergyar Rt.	Proceso de fermentacion metabolico controlado para la produccion de acido pseudomonico.
AU2002365431A1 (en) *	2001-12-28	2003-09-02	Teva Gyogyszergyar Reszvenytarsasag	Processes for preparing crystalline and amorphous mupirocin calcium
IL150907A (en) *	2002-07-25	2007-07-04	Stephan Cherkez	Process for the preparation of stable amorphous calcium pseudomonate
DE602005019509D1 (de)	2004-06-01	2010-04-08	Teva Gyogyszergyar Zartkoeruen	Verfahren für die zubereitung der amorphen form eines medikamentes
WO2006087237A1 (en)	2005-02-21	2006-08-24	Alpharma Aps	Purification of mupirocin
US20110008303A1 (en) *	2008-03-17	2011-01-13	Cedars-Sinai Medical Center	Methods for treatment and prevention of mrsa/mssa
CN104370896A (zh) *	2013-11-29	2015-02-25	江苏汉邦科技有限公司	一种纯化假单孢菌素的方法
CN103820369B (zh) *	2014-03-07	2015-11-18	浙江瑞邦药业有限公司	一种萤光假单胞菌及其应用
US12163135B2 (en)	2017-12-05	2024-12-10	BioPlx, Inc.	Methods and compositions to prevent microbial infection
CN108277243B (zh) *	2018-01-19	2021-03-12	浙江瑞邦药业股份有限公司	一种假单胞菌酸a的制备方法
CN108949845B (zh) *	2018-08-08	2021-08-10	福建康鸿生物科技有限公司	一种发酵培养基及由发酵培养基制备莫匹罗星的方法
CN116867905A (zh)	2021-02-07	2023-10-10	杭州中美华东制药有限公司	一种莫匹罗星的发酵方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1643240A1 (de) *	1966-09-16	1971-06-24	Boehringer Sohn Ingelheim	Verfahren zur Herstellung neuer racemischer oder optisch aktiver 1-Phenoxy-2-aminoalkane
US4071536A (en)	1971-06-12	1978-01-31	Beecham Group Limited	Antibiotics
US3977943A (en) *	1971-06-12	1976-08-31	Beecham Group Limited	Antibiotics
GB1395907A (en)	1971-06-12	1975-05-29	Beecham Group Ltd	Antibiotics
JPS5270083A (en) *	1975-12-04	1977-06-10	Yoshitomi Pharmaceut Ind Ltd	Manufacture of an antibiotics, trans-pseudomonic acid
GB1577730A (en) *	1976-10-23	1980-10-29	Beecham Group Ltd	Treatment of infections with pseudomonicacid salts or esters thereof
GB1577545A (en)	1977-07-27	1980-10-22	Beecham Group Ltd	Treatment of swine dysenter
CA1103264A (en) *	1977-09-30	1981-06-16	Norman H. Rogers	Purification of pseudomonic acid
CA1115699A (en) *	1978-05-20	1982-01-05	Alan D. Curzons	Lithium pseudomonate and its preparation
CA1196284A (en) *	1982-05-28	1985-11-05	Joshua Oduro-Yeboah	Pharmaceutical formulations
GB8415579D0 (en) *	1984-06-19	1984-07-25	Beecham Group Plc	Compounds
GB8428952D0 (en)	1984-11-16	1984-12-27	Beecham Group Plc	Formulations
GB8530796D0 (en)	1985-12-13	1986-01-22	Beecham Group Plc	Pharmaceutical composition
IE59628B1 (en) *	1986-06-26	1994-03-09	Beecham Group Plc	Treatment of fungal infections
IN171883B (no)	1990-07-27	1993-01-30	Hoechst India
US5594026A (en) *	1990-12-11	1997-01-14	Smithkline Beecham Group P.L.C.	Polymorphs of crystalline mupirocin
US5292892A (en)	1991-05-07	1994-03-08	Sankyo Company, Limited	Anti-bacterial compound and pharmaceutical compositions thereof
US6503881B2 (en) *	1996-08-21	2003-01-07	Micrologix Biotech Inc.	Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics
TR199900733T2 (xx) *	1996-10-01	1999-07-21	Smithkline Beecham Corporation	Patojenik organizmalar ile nasofarinksin kolonizasyonu ile ilgili bakteriyal enfeksiyonlar�n tedavisi i�in bir ilac�n imalat�nda mupirosin kullan�m�.
US6231875B1 (en) *	1998-03-31	2001-05-15	Johnson & Johnson Consumer Companies, Inc.	Acidified composition for topical treatment of nail and skin conditions
HRP20010576A2 (en)	1999-02-03	2002-08-31	Biogal Gyogyszergyar	Process for the preparation of pseudomonic acid a antibiotic by microbiological method
US6245921B1 (en)	1999-02-03	2001-06-12	Biogal Gyogyszergyar Rt.	Process for the isolation of pseudomonic acid A from pseudomonic acid complex-containing culture broth
US6335023B1 (en) *	1999-06-30	2002-01-01	Ruey J. Yu	Oligosaccharide aldonic acids and their topical use
US6528086B2 (en) *	1999-09-28	2003-03-04	Zars, Inc.	Methods and apparatus for drug delivery involving phase changing formulations
IL137363A (en)	2000-07-18	2005-12-18	Agis Ind 1983 Ltd	Pharmaceutical compositions containing mupirocin
IL150907A (en)	2002-07-25	2007-07-04	Stephan Cherkez	Process for the preparation of stable amorphous calcium pseudomonate

2000
- 2000-02-03 HR HR20010576A patent/HRP20010576A2/hr not_active Application Discontinuation
- 2000-02-03 US US09/497,807 patent/US6509177B1/en not_active Expired - Fee Related
- 2000-02-03 CA CA002360865A patent/CA2360865A1/en not_active Abandoned
- 2000-02-03 SK SK1089-2001A patent/SK10892001A3/sk unknown
- 2000-02-03 AU AU29808/00A patent/AU762768B2/en not_active Ceased
- 2000-02-03 MX MXPA01007806A patent/MXPA01007806A/es not_active Application Discontinuation
- 2000-02-03 TR TR2001/02234T patent/TR200102234T2/xx unknown
- 2000-02-03 CZ CZ20012724A patent/CZ20012724A3/cs unknown
- 2000-02-03 PL PL00358615A patent/PL358615A1/xx not_active Application Discontinuation
- 2000-02-03 EP EP00908473A patent/EP1151131A4/en not_active Withdrawn
- 2000-02-03 CN CNB008058784A patent/CN1203184C/zh not_active Expired - Fee Related
- 2000-02-03 CN CNA2005100056737A patent/CN1670217A/zh active Pending
- 2000-02-03 BR BR0009179-0A patent/BR0009179A/pt not_active IP Right Cessation
- 2000-02-03 HK HK02103290.9A patent/HK1041903A1/zh unknown
- 2000-02-03 IL IL14467900A patent/IL144679A0/xx active IP Right Grant
- 2000-02-03 HU HU0300363A patent/HUP0300363A2/hu unknown
- 2000-02-03 YU YU55601A patent/YU55601A/sh unknown
- 2000-02-03 KR KR1020017009825A patent/KR20010113674A/ko not_active Ceased
- 2000-02-03 JP JP2000597448A patent/JP2003515311A/ja not_active Ceased
- 2000-02-03 WO PCT/US2000/002880 patent/WO2000046389A1/en not_active Ceased
2001
- 2001-07-31 IS IS6028A patent/IS6028A/is unknown
- 2001-08-01 IL IL144679A patent/IL144679A/en not_active IP Right Cessation
- 2001-08-02 NO NO20013791A patent/NO20013791L/no not_active Application Discontinuation
- 2001-08-03 BG BG105776A patent/BG105776A/xx unknown
- 2001-10-11 US US09/975,796 patent/US6506591B2/en not_active Expired - Fee Related
2002
- 2002-11-12 US US10/293,675 patent/US7078223B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US20020042103A1 (en)	2002-04-11
CN1354798A (zh)	2002-06-19
WO2000046389A1 (en)	2000-08-10
AU762768B2 (en)	2003-07-03
TR200102234T2 (tr)	2002-10-21
US20030100083A1 (en)	2003-05-29
YU55601A (sh)	2003-02-28
JP2003515311A (ja)	2003-05-07
IL144679A (en)	2007-06-17
EP1151131A4 (en)	2004-05-12
US6506591B2 (en)	2003-01-14
HRP20010576A2 (en)	2002-08-31
CA2360865A1 (en)	2000-08-10
MXPA01007806A (es)	2003-06-04
AU2980800A (en)	2000-08-25
HUP0300363A2 (hu)	2004-06-28
PL358615A1 (en)	2004-08-09
IL144679A0 (en)	2002-06-30
US6509177B1 (en)	2003-01-21
BG105776A (en)	2002-05-31
US7078223B2 (en)	2006-07-18
SK10892001A3 (sk)	2002-06-04
CN1670217A (zh)	2005-09-21
KR20010113674A (ko)	2001-12-28
CN1203184C (zh)	2005-05-25
WO2000046389A9 (en)	2001-09-07
NO20013791L (no)	2001-10-02
BR0009179A (pt)	2001-11-27
IS6028A (is)	2001-07-31
EP1151131A1 (en)	2001-11-07
CZ20012724A3 (cs)	2001-12-12
HK1041903A1 (zh)	2002-07-26

Publication	Publication Date	Title
NO20013791D0 (no)	2001-08-02	Fremgangsmåte for fremstilling av pseudomonsyre A-antibiotika ved hjelp av en mikrobiologisk fremgangsmåte
NO20022171D0 (no)	2002-05-07	Fremgangsmåte for syntetisering av nukleinsyre
NO20013667L (no)	2001-07-26	Fremgangsmate ved fremstilling av 5-cyanoftalid
EP1230975A4 (en)	2003-07-16	METHOD FOR PRODUCING HEAT-ABSORBING MICRO-CAPSULES
NO20013569D0 (no)	2001-07-19	Fremgangsmåte ved fremstilling av L-fenylephrine-hydroklorid
NO20015316D0 (no)	2001-10-30	Optimalisering av fermenteringsprosess
AU3377500A (en)	2000-09-14	Method for extracting dna from dried specimens
IL144678A0 (en)	2002-06-30	Process for the isolation of pseudomonic acid a from pseudomonic acid complex-containing culture broth
AU2003237052A1 (en)	2004-01-19	Process for preparing (r)-aryloxypropionic acid ester derivatives
NO20014787D0 (no)	2001-10-01	Fremgangsmåte for fremstilling av hydroksymetyltiosmörsyre- estere
AU6018300A (en)	2001-02-05	Process for producing target substance by fermentation method
SI1214321T1 (en)	2004-12-31	Process for production of naphthyridine-3-carboxylic acid derivatives
AU2002345856A1 (en)	2003-01-08	Metabolic controlled fermentation process for pseudomonic acid production
EP1219714A3 (en)	2004-03-31	Method for production of geranylgeraniol and analogous compounds thereof by microorganisms
AU4750000A (en)	2000-11-10	Method for production of microcapsules
NO20014051D0 (no)	2001-08-20	Fremgangsmate for fremstilling av et noringsmiddel
NO20001985L (no)	2000-10-16	FremgangsmÕte for forming av strimmelformede folier
NO20021727D0 (no)	2002-04-12	Fremgangsmåte for fremstilling av 3,4-metylen-dioksy- mandelisk syre
AU3843900A (en)	2000-10-16	Microbiological production method for alpha-l-aspartyl-l-phenylalanine
AU4277001A (en)	2001-10-03	Process for producing l-amino acid via fermentation method
NO20033126L (no)	2003-09-08	Metabolsk kontrollert fermenteringsprosess for karbamoyltobramycinproduksjon
AU6018400A (en)	2001-02-05	Process for producing target substance by fermentation method
FR2796939B1 (fr)	2001-09-14	Procede de fabrication de la cyanhydrine de la methyl ethyl cetone
NO994108D0 (no)	1999-08-25	Fremgangsmåte ved fremstilling av 4H-4-okso-kinolizin-3-karboksylsyrederivater
AU2003261948A1 (en)	2004-04-30	Process for production of 2-(hydroxymethyl)cyclo- propanecarboxylic acids

Legal Events

Date	Code	Title	Description
2006-10-02	FC2A	Withdrawal, rejection or dismissal of laid open patent application