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NO20010252L - Bispiperidiner som antitrombotiske midler - Google Patents

Bispiperidiner som antitrombotiske midler

Info

Publication number
NO20010252L
NO20010252L NO20010252A NO20010252A NO20010252L NO 20010252 L NO20010252 L NO 20010252L NO 20010252 A NO20010252 A NO 20010252A NO 20010252 A NO20010252 A NO 20010252A NO 20010252 L NO20010252 L NO 20010252L
Authority
NO
Norway
Prior art keywords
antithrombotic agents
bispiperidines
therepeutically
fibrinogen
iib
Prior art date
Application number
NO20010252A
Other languages
English (en)
Other versions
NO318963B1 (no
NO20010252D0 (no
Inventor
Christophe Yue
Marguerite Henry
Thierry Giboulot
Brigitte Lesur
Original Assignee
Lafon Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lafon Labor filed Critical Lafon Labor
Publication of NO20010252D0 publication Critical patent/NO20010252D0/no
Publication of NO20010252L publication Critical patent/NO20010252L/no
Publication of NO318963B1 publication Critical patent/NO318963B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Materials For Medical Uses (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20010252A 1998-07-17 2001-01-15 Forbindelser og fremgangsmate for fremstilling derav, terapeutiske preparater, anvendelser av forbindelsene og mellomprodukter. NO318963B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9809166A FR2781223B1 (fr) 1998-07-17 1998-07-17 Bispiperidines et leurs applications therapeutiques
PCT/FR1999/001745 WO2000003986A1 (fr) 1998-07-17 1999-07-16 Bispiperidines comme agents antithrombotiques

Publications (3)

Publication Number Publication Date
NO20010252D0 NO20010252D0 (no) 2001-01-15
NO20010252L true NO20010252L (no) 2001-03-19
NO318963B1 NO318963B1 (no) 2005-05-30

Family

ID=9528732

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20010252A NO318963B1 (no) 1998-07-17 2001-01-15 Forbindelser og fremgangsmate for fremstilling derav, terapeutiske preparater, anvendelser av forbindelsene og mellomprodukter.

Country Status (25)

Country Link
US (1) US6333338B1 (no)
EP (1) EP1098878B1 (no)
JP (1) JP2002520393A (no)
KR (1) KR100584032B1 (no)
CN (1) CN1286812C (no)
AT (1) ATE256661T1 (no)
AU (1) AU761655B2 (no)
BR (1) BR9912835A (no)
CA (1) CA2337776A1 (no)
DE (1) DE69913701T2 (no)
DK (1) DK1098878T3 (no)
EA (1) EA003674B1 (no)
ES (1) ES2212576T3 (no)
FR (1) FR2781223B1 (no)
HU (1) HUP0103623A3 (no)
IL (2) IL140581A0 (no)
NO (1) NO318963B1 (no)
NZ (1) NZ509170A (no)
PL (1) PL193804B1 (no)
PT (1) PT1098878E (no)
SK (1) SK152001A3 (no)
TR (1) TR200100159T2 (no)
UA (1) UA65631C2 (no)
WO (1) WO2000003986A1 (no)
ZA (1) ZA200100238B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1244616A1 (en) * 1999-12-24 2002-10-02 SmithKline Beecham plc (hetero)bicyclylmethanesulfonylamino-substituted hydroxamic acid derivatives
US7365223B2 (en) * 2003-06-18 2008-04-29 Nst Neurosurvival Technologies Ltd Method for selective targeting of apoptotic cells and small molecule ligands used thereof
JP7775080B2 (ja) 2019-07-01 2025-11-25 トニックス ファーマ リミテッド 抗cd154抗体およびその使用
MX2023008055A (es) 2021-01-06 2023-08-22 Tonix Pharma Ltd Métodos para inducir tolerancia inmune con anticuerpos anti-cd154 modificados.
WO2025248134A1 (en) 2024-05-31 2025-12-04 Tonix Pharma Limited Treatment methods comprising administration of modified cd154 antibodies

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL99538A0 (en) * 1990-09-27 1992-08-18 Merck & Co Inc Fibrinogen receptor antagonists and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
US6333338B1 (en) 2001-12-25
DE69913701T2 (de) 2004-10-21
BR9912835A (pt) 2001-10-09
ZA200100238B (en) 2001-11-21
DE69913701D1 (de) 2004-01-29
CN1312799A (zh) 2001-09-12
CN1286812C (zh) 2006-11-29
IL140581A (en) 2006-12-31
WO2000003986A1 (fr) 2000-01-27
EP1098878B1 (fr) 2003-12-17
IL140581A0 (en) 2002-02-10
PL345418A1 (en) 2001-12-17
UA65631C2 (en) 2004-04-15
SK152001A3 (en) 2001-11-06
FR2781223A1 (fr) 2000-01-21
NZ509170A (en) 2004-01-30
PT1098878E (pt) 2004-04-30
HUP0103623A3 (en) 2003-01-28
CA2337776A1 (en) 2000-01-27
AU761655B2 (en) 2003-06-05
TR200100159T2 (tr) 2001-06-21
EA200100150A1 (ru) 2001-08-27
ES2212576T3 (es) 2004-07-16
EP1098878A1 (fr) 2001-05-16
KR20010071925A (ko) 2001-07-31
EA003674B1 (ru) 2003-08-28
JP2002520393A (ja) 2002-07-09
DK1098878T3 (da) 2004-02-16
NO318963B1 (no) 2005-05-30
FR2781223B1 (fr) 2000-10-13
ATE256661T1 (de) 2004-01-15
HUP0103623A2 (hu) 2002-02-28
AU4629099A (en) 2000-02-07
KR100584032B1 (ko) 2006-05-29
NO20010252D0 (no) 2001-01-15
PL193804B1 (pl) 2007-03-30

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