[go: up one dir, main page]

NO20005084D0 - Heterocyclic glycyl <beta> -alanine derivatives as vitronectin antagonists - Google Patents

Heterocyclic glycyl <beta> -alanine derivatives as vitronectin antagonists

Info

Publication number
NO20005084D0
NO20005084D0 NO20005084A NO20005084A NO20005084D0 NO 20005084 D0 NO20005084 D0 NO 20005084D0 NO 20005084 A NO20005084 A NO 20005084A NO 20005084 A NO20005084 A NO 20005084A NO 20005084 D0 NO20005084 D0 NO 20005084D0
Authority
NO
Norway
Prior art keywords
glycyl
heterocyclic
beta
alanine derivatives
vitronectin antagonists
Prior art date
Application number
NO20005084A
Other languages
Norwegian (no)
Other versions
NO20005084L (en
Inventor
Nizal Samuel Chandrakumar
Bipinchandra Nanubhai Desai
Balekudru Devadas
Renee Huff
Ish K Khanna
Shashidhar N Rao
Joseph G Rico
Thomas E Rogers
Peter G Ruminski
Mark Andrew Russell
Yi Yu
Alan Frank Gasiecki
James W Malecha
Julie M Miyashiro
Original Assignee
G D Searle & Co Corporate Pate
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by G D Searle & Co Corporate Pate filed Critical G D Searle & Co Corporate Pate
Publication of NO20005084D0 publication Critical patent/NO20005084D0/en
Publication of NO20005084L publication Critical patent/NO20005084L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
NO20005084A 1998-04-10 2000-10-09 Heterocyclic glycyl <beta> -alanine derivatives as vitronectin antagonists NO20005084L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8139498P 1998-04-10 1998-04-10
PCT/US1999/004297 WO1999052896A1 (en) 1998-04-10 1999-04-09 Heterocyclic glycyl beta-alanine derivatives as vitronectin antagonists

Publications (2)

Publication Number Publication Date
NO20005084D0 true NO20005084D0 (en) 2000-10-09
NO20005084L NO20005084L (en) 2000-11-27

Family

ID=22163868

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005084A NO20005084L (en) 1998-04-10 2000-10-09 Heterocyclic glycyl <beta> -alanine derivatives as vitronectin antagonists

Country Status (17)

Country Link
EP (1) EP1070060A1 (en)
JP (1) JP2002511462A (en)
KR (1) KR20010042614A (en)
CN (1) CN1304406A (en)
AR (1) AR015759A1 (en)
AU (1) AU765294B2 (en)
BR (1) BR9910119A (en)
CA (1) CA2326665A1 (en)
CZ (1) CZ20003672A3 (en)
IL (1) IL138677A0 (en)
MY (1) MY133473A (en)
NO (1) NO20005084L (en)
NZ (1) NZ507292A (en)
PL (1) PL343406A1 (en)
RU (1) RU2215746C2 (en)
TW (1) TWI247008B (en)
WO (1) WO1999052896A1 (en)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6172256B1 (en) * 1998-03-04 2001-01-09 G.D. Searle & Co. Chiral-β-amino acid compounds and derivatives thereof
GB9805655D0 (en) 1998-03-16 1998-05-13 Celltech Therapeutics Ltd Chemical compounds
US6521626B1 (en) 1998-03-24 2003-02-18 Celltech R&D Limited Thiocarboxamide derivatives
GB9814414D0 (en) 1998-07-03 1998-09-02 Celltech Therapeutics Ltd Chemical compounds
GB9821061D0 (en) 1998-09-28 1998-11-18 Celltech Therapeutics Ltd Chemical compounds
GB9826174D0 (en) 1998-11-30 1999-01-20 Celltech Therapeutics Ltd Chemical compounds
PL350291A1 (en) * 1998-12-23 2002-12-02 Searle & Co Method of using a cyclooxygenase-2 inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
EP1156803A4 (en) 1999-02-09 2004-03-17 Bristol Myers Squibb Co LACTAM INHIBITORS OF FXa AND METHOD
GB9908355D0 (en) * 1999-04-12 1999-06-09 Rhone Poulenc Rorer Ltd Chemical compounds
CA2369728A1 (en) 1999-04-12 2000-10-19 Aventis Pharma Limited Substituted bicyclic heteroaryl compounds as integrin antagonists
AU4551500A (en) * 1999-04-28 2000-11-17 Basf Aktiengesellschaft Integrin receptor antagonists
US6518283B1 (en) 1999-05-28 2003-02-11 Celltech R&D Limited Squaric acid derivatives
US6455539B2 (en) 1999-12-23 2002-09-24 Celltech R&D Limited Squaric acid derivates
ES2295150T3 (en) 2000-04-17 2008-04-16 Ucb Pharma, S.A. ENAMINE DERIVATIVES AS CELLULAR ADHESION MOLECULES.
US6545013B2 (en) 2000-05-30 2003-04-08 Celltech R&D Limited 2,7-naphthyridine derivatives
US6403608B1 (en) 2000-05-30 2002-06-11 Celltech R&D, Ltd. 3-Substituted isoquinolin-1-yl derivatives
JP2004503540A (en) 2000-06-15 2004-02-05 ファルマシア・コーポレーション Dihydrostilbene alkanoic acid derivatives useful as integrin antagonists
AU2001275724A1 (en) 2000-08-02 2002-02-13 Celltech R&D Limited 3-substituted isoquinolin-1-yl derivatives
US6511973B2 (en) 2000-08-02 2003-01-28 Bristol-Myers Squibb Co. Lactam inhibitors of FXa and method
DE10204789A1 (en) * 2002-02-06 2003-08-14 Merck Patent Gmbh Inhibitors of the integrin alpha¶v¶beta6
TW200307671A (en) 2002-05-24 2003-12-16 Elan Pharm Inc Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins
BR0317487A (en) * 2002-12-20 2005-11-29 Pharmacia Corp The r-isomer of beta amino acid compounds as derivatives of integrin receptor antagonists
UA87854C2 (en) 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
EP2205599B1 (en) 2007-10-18 2012-06-06 Boehringer Ingelheim International GmbH Cgrp antagonists
EP2065381A1 (en) 2007-10-18 2009-06-03 Boehringer Ingelheim Pharma GmbH & Co. KG CGRP antagonists
EP2225223B1 (en) 2007-11-22 2017-01-11 Boehringer Ingelheim International GmbH Organic compounds
WO2009065922A2 (en) * 2007-11-22 2009-05-28 Boehringer Ingelheim International Gmbh Novel compounds
US8716226B2 (en) 2012-07-18 2014-05-06 Saint Louis University 3,5 phenyl-substituted beta amino acid derivatives as integrin antagonists
IN2015DN00099A (en) 2012-07-18 2015-05-29 Univ Saint Louis
MX2016015467A (en) 2014-05-30 2017-03-23 Pfizer Carbonitrile derivatives as selective androgen receptor modulators.
CN108779077A (en) 2015-12-30 2018-11-09 圣路易斯大学 Meta position azacyclic amino benzoic acid derivatives as PAN integrin antagonists
CA3042693A1 (en) * 2016-11-08 2018-05-17 Bristol-Myers Squibb Company Pyrrole amides as .alpha.v integrin inhibitors
JP7661969B2 (en) * 2020-05-14 2025-04-15 Ube株式会社 1,4,5,6-Tetrahydropyrimidin-2-amine derivatives
WO2023275715A1 (en) 2021-06-30 2023-01-05 Pfizer Inc. Metabolites of selective androgen receptor modulators
EP4431098A4 (en) 2021-11-12 2025-10-08 Ube Corp Pharmaceutical composition for the treatment of Alport syndrome
CN115626912B (en) * 2022-09-27 2024-03-26 中山大学 Thiourea compound and preparation method and application thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120859A (en) * 1989-09-22 1992-06-09 Genentech, Inc. Chimeric amino acid analogues
FR2676054B1 (en) * 1991-05-03 1993-09-03 Sanofi Elf NOVEL N-ALKYLENEPIPERIDINO COMPOUNDS AND THEIR ENANTIOMERS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
RU2126001C1 (en) * 1995-01-10 1999-02-10 Самдзин Фармасьютикал Ко., Лтд Piperazine derivatives and pharmaceutical composition on their basis
JPH11510814A (en) * 1995-08-30 1999-09-21 ジー.ディー.サール アンド カンパニー Meta-guanidine, urea, thiourea or azacyclic aminobenzoic acid derivatives as integrin antagonists
DE19629816A1 (en) * 1996-07-24 1998-01-29 Hoechst Ag New cycloalkyl derivatives as inhibitors of bone resorption and vitronectin receptor antagonists
WO1998008840A1 (en) * 1996-08-29 1998-03-05 Merck & Co., Inc. Integrin antagonists

Also Published As

Publication number Publication date
TWI247008B (en) 2006-01-11
IL138677A0 (en) 2001-10-31
KR20010042614A (en) 2001-05-25
JP2002511462A (en) 2002-04-16
AU765294B2 (en) 2003-09-11
NO20005084L (en) 2000-11-27
NZ507292A (en) 2003-12-19
AU3449999A (en) 1999-11-01
BR9910119A (en) 2001-10-09
RU2215746C2 (en) 2003-11-10
PL343406A1 (en) 2001-08-13
CZ20003672A3 (en) 2001-08-15
CA2326665A1 (en) 1999-10-21
MY133473A (en) 2007-11-30
WO1999052896A1 (en) 1999-10-21
AR015759A1 (en) 2001-05-16
CN1304406A (en) 2001-07-18
EP1070060A1 (en) 2001-01-24

Similar Documents

Publication Publication Date Title
NO20005084D0 (en) Heterocyclic glycyl &lt;beta&gt; -alanine derivatives as vitronectin antagonists
NO20013559L (en) Aromatic heterocyclic compounds as anti-inflammatory agents
NO20000885L (en) 4-Phenyl-pyridine derivatives
DE60009747D1 (en) ADMANTAN DERIVATIVES
DE50010060D1 (en) THIAZOLYLAMID DERIVATIVES
NO20021459L (en) Piperazine derivatives as 5-HT1B antagonists
DK1097127T3 (en) Diacylhydrazine derivatives as integrin inhibitors
EE200100613A (en) 13-methylerythromycin derivatives
DK1187814T3 (en) 5-phenyl-pyrimidine derivatives
DK1202953T3 (en) Substituted 2-dialkylaminoalkylbiphenyl derivatives
PT1237857E (en) NEW FENALQUILOXY-PHENYL DERIVATIVES
ATE257148T1 (en) PROPARGYLETHER DERIVATIVES
DK1154988T3 (en) Mevinoline derivatives
ATE374747T1 (en) MONOFLUORALKYL DERIVATIVES
NO20021251D0 (en) Tienoisoxazolyl- and thienylpyrrazolyl-phenoxy-substituted propyl derivatives useful as D4 antagonists
DK1187815T3 (en) 4-phenyl-pyrimidine derivatives
DK1218340T3 (en) 4-hydroxybiphenylhydrazid derivatives
ATE293592T1 (en) RESOCINE DERIVATIVES
NO20023001D0 (en) Substituted piperazine derivatives as MTP inhibitors
TR200002831A3 (en) Quinolin-4-Il derivatives I
DE60025348D1 (en) Ethanesulfonyl-PIPERIDINE DERIVATIVES
DK1178984T3 (en) 1-trifluoromethyl-4-hydroxy-7-piperidinylaminomethylchroman derivatives
NO20022682D0 (en) Heterocyclic derivatives
ATE269328T1 (en) 1-CYCLOALKYLPYRAZOLYL-BENZOYL DERIVATIVES
NO20021249L (en) Tienoisoxazolphenoxy substituted ethyl and propyl derivatives useful as D4 antagonists

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application