[go: up one dir, main page]

NO20001500D0 - Tricykliske triazolbenzazepinderivater, fremgangsmåte til fremstilling derav, samt antiallergiske midler - Google Patents

Tricykliske triazolbenzazepinderivater, fremgangsmåte til fremstilling derav, samt antiallergiske midler

Info

Publication number
NO20001500D0
NO20001500D0 NO20001500A NO20001500A NO20001500D0 NO 20001500 D0 NO20001500 D0 NO 20001500D0 NO 20001500 A NO20001500 A NO 20001500A NO 20001500 A NO20001500 A NO 20001500A NO 20001500 D0 NO20001500 D0 NO 20001500D0
Authority
NO
Norway
Prior art keywords
antiallergic agents
preparation
alkyl
benzazepine derivatives
chem
Prior art date
Application number
NO20001500A
Other languages
English (en)
Other versions
NO319542B1 (no
NO20001500L (no
Inventor
Yasuo Ohtsuka
Toshio Nishizuka
Sohjiro Shiokawa
Seiji Tsutsumi
Mami Kawaguchi
Hideo Kitagawa
Hiromi Takata
Takashi Shishikura
Toyoaki Ishikura
Kenichi Fushihara
Yumiko Okada
Sachiko Miyamoto
Maki Shiobara
Original Assignee
Meiji Seika Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha filed Critical Meiji Seika Kaisha
Publication of NO20001500D0 publication Critical patent/NO20001500D0/no
Publication of NO20001500L publication Critical patent/NO20001500L/no
Publication of NO319542B1 publication Critical patent/NO319542B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/041,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO20001500A 1997-09-29 2000-03-23 Tricykliske triazolbenzazepinderivater, fremgangsmate til fremstilling derav, samt antiallergiske midler NO319542B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP26461197 1997-09-29
JP5206398 1998-03-04
PCT/JP1998/004363 WO1999016770A1 (en) 1997-09-29 1998-09-29 Tricyclic triazolobenzazepine derivatives, process for producing the same, and antiallergic

Publications (3)

Publication Number Publication Date
NO20001500D0 true NO20001500D0 (no) 2000-03-23
NO20001500L NO20001500L (no) 2000-05-18
NO319542B1 NO319542B1 (no) 2005-08-29

Family

ID=26392670

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20001500A NO319542B1 (no) 1997-09-29 2000-03-23 Tricykliske triazolbenzazepinderivater, fremgangsmate til fremstilling derav, samt antiallergiske midler
NO20043765A NO20043765L (no) 1997-09-29 2004-09-08 Tricykliske triazolbenzazepinderivater, fremgangsmate til fremstilling derav, samt antiallergiske midler

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20043765A NO20043765L (no) 1997-09-29 2004-09-08 Tricykliske triazolbenzazepinderivater, fremgangsmate til fremstilling derav, samt antiallergiske midler

Country Status (24)

Country Link
US (3) US6372735B1 (no)
EP (1) EP1026167B1 (no)
JP (1) JP3188482B2 (no)
KR (1) KR100389140B1 (no)
CN (2) CN1155599C (no)
AT (1) ATE233764T1 (no)
AU (1) AU744636B2 (no)
BR (1) BR9814055B1 (no)
CA (1) CA2305307C (no)
DE (1) DE69811930T2 (no)
DK (1) DK1026167T3 (no)
ES (1) ES2191963T3 (no)
HU (1) HUP0004020A3 (no)
ID (1) ID24101A (no)
IL (1) IL135303A0 (no)
NO (2) NO319542B1 (no)
NZ (1) NZ503601A (no)
PL (1) PL339544A1 (no)
PT (1) PT1026167E (no)
RU (1) RU2198885C2 (no)
SK (1) SK283869B6 (no)
TR (1) TR200000808T2 (no)
TW (1) TW510902B (no)
WO (1) WO1999016770A1 (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE410427T1 (de) * 2001-12-26 2008-10-15 Meiji Seika Kaisha Neues kristallines tricyclisches triazolobenzazepinderivat
WO2003064400A1 (en) * 2002-02-01 2003-08-07 Meiji Seika Kaisha, Ltd. Process for producing 1,2,3-triazole compound
NZ537251A (en) 2002-07-09 2007-02-23 Bristol Myers Squibb Co Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method
AU2003259131A1 (en) 2002-07-09 2004-01-23 Bristol-Myers Squibb Company Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method
JPWO2004113343A1 (ja) * 2003-06-19 2006-08-31 明治製菓株式会社 三環性トリアゾロベンゾアゼピン誘導体の新規結晶性物質
WO2004113451A1 (ja) * 2003-06-20 2004-12-29 Meiji Seika Kaisha, Ltd. 難溶性物質と水溶性高分子との共沈物およびその製造方法
NZ551370A (en) 2004-05-14 2009-08-28 Millennium Pharm Inc Compounds and methods for inhibiting mitotic progression by inhibiting of aurora kinase
MX2008011178A (es) * 2006-03-02 2008-09-25 Meiji Seika Kaisha Agente profilàctico o terapèutico para enfermedad oftàlmica alèrgica o enfermedad nasal alèrgica, que comprende derivado tricìclico de triazolobenzacepina.
US8242105B2 (en) * 2006-09-25 2012-08-14 Forschungsverbund Berlin E.V. Structural mimetics of proline-rich peptides and the pharmaceutical use thereof
CL2007003244A1 (es) * 2006-11-16 2008-04-04 Millennium Pharm Inc Compuestos derivados de pirimido[5,4-d][2]benzazepina; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento del cancer.
WO2009078444A1 (ja) 2007-12-18 2009-06-25 Meiji Seika Kaisha, Ltd. 炎症性腸疾患の予防または治療剤
CA2747326C (en) 2008-12-22 2017-05-16 Millennium Pharmaceuticals, Inc. Combination of aurora kinase inhibitors and anti-cd20 antibodies
JO3635B1 (ar) 2009-05-18 2020-08-27 Millennium Pharm Inc مركبات صيدلانية صلبة وطرق لانتاجها
WO2011084848A2 (en) * 2010-01-07 2011-07-14 Alkermes, Inc. Prodrugs of heteraromatic compounds
BR112012020557A8 (pt) 2010-02-19 2018-01-02 Millennium Pharm Inc formas cristalinas de 4-{[9-cloro-7-(2-flúor-6-metoifenil)-5h-pirimido[5,4-d][2]benzazepin-2-il]amino}-2-metoxibenzoato de sódio
US20130303519A1 (en) 2012-03-20 2013-11-14 Millennium Pharmaceuticals, Inc. Methods of treating cancer using aurora kinase inhibitors
CA2907726A1 (en) 2013-03-22 2014-09-25 Millennium Pharmaceuticals, Inc. Combination of catalytic mtorc1/2 inhibitors and selective inhibitors of aurora a kinase
US20180207173A1 (en) 2015-07-21 2018-07-26 Millennium Pharmaceuticals, Inc. Administration of aurora kinase inhibitor and chemotherapeutic agents
PE20201500A1 (es) * 2017-12-29 2020-12-29 Biomarin Pharm Inc Inhibidores de glicolato oxidasa para el tratamiento de enfermedades

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE167662T1 (de) 1993-04-16 1998-07-15 Shionogi & Co Verfahren zur herstellung eines lignan-derivats
US5686442A (en) 1993-12-28 1997-11-11 Meiji Seika Kabushiki Kaisha Tricyclic benzazepine and benzothiazepine derivatives
EP0834512A4 (en) * 1995-06-15 2001-08-22 Meiji Seika Kaisha TRICLYCLIC BENZAZEPINE COMPOUNDS.
IL126095A0 (en) * 1996-03-08 1999-05-09 Zeneca Ltd Azolobenzazepine derivatives as neurogically active agents
US20070059533A1 (en) * 2005-09-12 2007-03-15 Burdette Steven R Thermal reflow of glass and fused silica body

Also Published As

Publication number Publication date
BR9814055A (pt) 2000-09-26
DK1026167T3 (da) 2003-05-26
SK4252000A3 (en) 2000-10-09
ID24101A (id) 2000-07-06
NZ503601A (en) 2002-02-01
CN1312135C (zh) 2007-04-25
AU744636B2 (en) 2002-02-28
TW510902B (en) 2002-11-21
US20020137739A1 (en) 2002-09-26
HUP0004020A3 (en) 2002-12-28
EP1026167B1 (en) 2003-03-05
HUP0004020A2 (hu) 2001-09-28
WO1999016770A1 (en) 1999-04-08
RU2198885C2 (ru) 2003-02-20
BR9814055B1 (pt) 2009-05-05
NO319542B1 (no) 2005-08-29
EP1026167A4 (en) 2001-07-11
CN1155599C (zh) 2004-06-30
CN1278262A (zh) 2000-12-27
KR20010030784A (ko) 2001-04-16
NO20043765L (no) 2000-05-18
US6372735B1 (en) 2002-04-16
ATE233764T1 (de) 2003-03-15
TR200000808T2 (tr) 2000-08-21
SK283869B6 (sk) 2004-03-02
US20060074074A1 (en) 2006-04-06
US7022860B2 (en) 2006-04-04
DE69811930T2 (de) 2003-12-18
US7238812B2 (en) 2007-07-03
ES2191963T3 (es) 2003-09-16
DE69811930D1 (de) 2003-04-10
PT1026167E (pt) 2003-07-31
CA2305307C (en) 2004-11-30
PL339544A1 (en) 2000-12-18
KR100389140B1 (ko) 2003-06-25
NO20001500L (no) 2000-05-18
EP1026167A1 (en) 2000-08-09
CN1523019A (zh) 2004-08-25
HK1032782A1 (en) 2002-08-30
CA2305307A1 (en) 1999-04-08
JP3188482B2 (ja) 2001-07-16
AU9186998A (en) 1999-04-23
IL135303A0 (en) 2001-05-20

Similar Documents

Publication Publication Date Title
NO20001500D0 (no) Tricykliske triazolbenzazepinderivater, fremgangsmåte til fremstilling derav, samt antiallergiske midler
DK1029853T3 (da) Heteroaromatiske bicykliske derivativer, der er egnede som anticancermidler
DK0928788T3 (da) Imidazolidin-4-on-derivater, der er nyttige som anticancer-midler
BG106340A (en) Substituted oxoazaheterocyclyl compounds
TW283624B (no)
NZ519241A (en) Tricyclic fused heterocyclic compound, process for preparing it and medicament comprising it
EP0902007A4 (en) CHALCONE DERIVATIVES AND MEDICINES CONTAINING THEM
HU9401974D0 (en) New intermediates for producing 9-[(substituted glicyl)-amido]-6-demetyl-6-deoxy-tetracyclines and pharmaceutical compositions containing them
HUT74182A (en) Novel imidazole derivatives, process for producing the same and pharmaceutical compositions containing the compounds
DK0918776T3 (da) Totalsyntese af antitumor acylfulvener
ATE271045T1 (de) Sauerstoffhaltige heterocyclische verbindungen
AU3415599A (en) Benzoheterocyclic distamycin derivatives, process for preparing them, and their use as antitumor agents
PL359415A1 (en) Oxadiazole derivatives having anticancer effects
NZ332923A (en) Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
EP1094055A4 (en) NEW VINYLBENZENE DERIVATIVES
ZA9811380B (no)
AR017971A1 (es) DERIVADOS TRICíCLICOS DE TRIAZOLBENZAZEPINAS, PROCEDIMIENTO PARA PRODUCIR LOS MISMOS, COMPOSICIONES FARMACEUTICAS FORMULADAS CON DICHOS COMPUESTOS Y COMPUESTOS INTERMEDIARIOS DE APLICACION EN DICHO PROCEDIMIENTO Y LA PEPARACION DE LOS MISMOS.
AU7332996A (en) Therapeutics for thrombocytopenia
AU2639999A (en) Intermediate compounds in the synthesis of the a ring moiety of 2-substituted vitamin d derivatives
EP0502488A3 (en) Phosphorus-containing azetidin-2-one derivatives
EP1251129A4 (en) PYRIMIDINE DERIVATIVES WITH ANTI-TUMOR EFFECT
MX9704976A (es) Derivados de 1,2,3-benzotiadiazol.