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NO138250C - ANALOGICAL PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE BENZYLAMINES - Google Patents

ANALOGICAL PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE BENZYLAMINES

Info

Publication number
NO138250C
NO138250C NO741350A NO741350A NO138250C NO 138250 C NO138250 C NO 138250C NO 741350 A NO741350 A NO 741350A NO 741350 A NO741350 A NO 741350A NO 138250 C NO138250 C NO 138250C
Authority
NO
Norway
Prior art keywords
benzylamines
preparation
pharmacologically active
analogical procedure
analogical
Prior art date
Application number
NO741350A
Other languages
Norwegian (no)
Other versions
NO741350L (en
NO138250B (en
Inventor
Johannes Keck
Klaus-Reinhold Noll
Helmut Pieper
Gerd Krueger
Sigfrid Pueschmann
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19732318636 external-priority patent/DE2318636B2/en
Priority claimed from DE19742402989 external-priority patent/DE2402989C3/en
Priority claimed from DE19742405322 external-priority patent/DE2405322A1/en
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO741350L publication Critical patent/NO741350L/en
Publication of NO138250B publication Critical patent/NO138250B/en
Publication of NO138250C publication Critical patent/NO138250C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/10Expectorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/24Camphidines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO741350A 1973-04-13 1974-04-10 ANALOGICAL PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE BENZYLAMINES NO138250C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19732318636 DE2318636B2 (en) 1973-04-13 1973-04-13 NEW BENZYLAMINES, MEDICINAL PRODUCTS AND THE METHOD OF MANUFACTURING THEM
DE19742402989 DE2402989C3 (en) 1974-01-23 1974-01-23 New benzylamines, pharmaceuticals containing them and processes for their manufacture
DE19742405322 DE2405322A1 (en) 1974-02-05 1974-02-05 NEW METHODS FOR MANUFACTURING BENZYLAMINES

Publications (3)

Publication Number Publication Date
NO741350L NO741350L (en) 1974-10-15
NO138250B NO138250B (en) 1978-04-24
NO138250C true NO138250C (en) 1978-08-02

Family

ID=27185183

Family Applications (1)

Application Number Title Priority Date Filing Date
NO741350A NO138250C (en) 1973-04-13 1974-04-10 ANALOGICAL PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE BENZYLAMINES

Country Status (19)

Country Link
JP (1) JPS5634582B2 (en)
AT (1) AT332375B (en)
BG (1) BG25787A3 (en)
CA (1) CA1011748A (en)
CH (2) CH609041A5 (en)
CS (1) CS188920B2 (en)
DD (1) DD113748A5 (en)
ES (1) ES424432A1 (en)
FR (1) FR2225165B1 (en)
GB (1) GB1469187A (en)
HU (1) HU167971B (en)
IE (1) IE40146B1 (en)
IL (1) IL44623A (en)
NL (1) NL7404965A (en)
NO (1) NO138250C (en)
PL (2) PL89811B1 (en)
RO (3) RO70260A (en)
SE (1) SE411749B (en)
SU (2) SU517250A3 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT327876B (en) * 1974-01-19 1976-02-25 Thomae Gmbh Dr K PROCESS FOR THE PRODUCTION OF HALOGENATED 2-AMINO-BENZYLAMINES AND THEIR ACID ADDITION SALTS
DE2926472A1 (en) * 1979-06-30 1981-01-15 Thomae Gmbh Dr K NEW BENZOYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS
US4735959A (en) * 1981-01-10 1988-04-05 Dr. Karl Thomae Gmbh Carboxylic acid amides and pharmaceutical compositions containing them
DE3100575A1 (en) * 1981-01-10 1982-09-02 Dr. Karl Thomae Gmbh, 7950 Biberach "NEW BENZOESAEURS, THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS"
JPS60146849A (en) * 1984-01-09 1985-08-02 Mitsui Toatsu Chem Inc Preparation of aminobenzylamine
JPH0365264A (en) * 1989-08-03 1991-03-20 Sanko Denki Seisakusho:Kk Spraying device
DE19529431C1 (en) * 1995-08-10 1996-12-12 Boehringer Ingelheim Kg Prepn. of benzylamine derivs., by redn. of corresp. nitro cpd in presence of iron@
CN112279774B (en) * 2019-07-24 2023-05-30 成都施贝康生物医药科技有限公司 Dibromobenzyl derivative, stereoisomer or salt thereof, preparation method and application

Also Published As

Publication number Publication date
IE40146B1 (en) 1979-03-28
RO69152A (en) 1981-01-30
FR2225165B1 (en) 1977-09-09
SU517250A3 (en) 1976-06-05
HU167971B (en) 1976-01-28
GB1469187A (en) 1977-03-30
IE40146L (en) 1974-10-13
BG25787A3 (en) 1978-12-12
FR2225165A1 (en) 1974-11-08
PL102867B1 (en) 1979-04-30
PL89811B1 (en) 1976-12-31
RO69291A (en) 1983-04-29
NL7404965A (en) 1974-10-15
RO70260A (en) 1980-03-15
CH609327A5 (en) 1979-02-28
SU521836A3 (en) 1976-07-15
IL44623A (en) 1978-01-31
JPS5634582B2 (en) 1981-08-11
ES424432A1 (en) 1976-06-01
CA1011748A (en) 1977-06-07
JPS5012030A (en) 1975-02-07
AT332375B (en) 1976-09-27
DD113748A5 (en) 1975-06-20
NO741350L (en) 1974-10-15
SE411749B (en) 1980-02-04
RO69291B (en) 1983-04-30
ATA202374A (en) 1976-01-15
IL44623A0 (en) 1974-06-30
NO138250B (en) 1978-04-24
CS188920B2 (en) 1979-03-30
CH609041A5 (en) 1979-02-15

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