NO136574C - ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE PYRIMIDINE DERIVATIVES. - Google Patents

ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE PYRIMIDINE DERIVATIVES.

Info

Publication number: NO136574C
Authority: NO; Norway
Prior art keywords: preparation; therapeutically active; pyrimidine derivatives; active pyrimidine; analogical procedure
Prior art date: 1971-10-29

Application number

NO3686/72A

Other languages

Norwegian (no)

Other versions

NO136574B (en

Inventor

Christopher Andrew Lipinski

John Gerritt Stam

Gerald George Deangelis

Hans-Jurgen Ernst Hess

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-10-29

Filing date

1972-10-13

Publication date

1977-09-28

1972-10-13 Application filed by Pfizer filed Critical Pfizer

1976-11-08 Priority to NO763797A priority Critical patent/NO137596C/en

1977-06-20 Publication of NO136574B publication Critical patent/NO136574B/no

1977-09-28 Publication of NO136574C publication Critical patent/NO136574C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO3686/72A 1971-10-29 1972-10-13 ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE PYRIMIDINE DERIVATIVES. NO136574C (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
NO763797A NO137596C (en)	1971-10-29	1976-11-08	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE HYDROXY-PYRIMIDINE DERIVATIVES

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US19400671A	1971-10-29	1971-10-29

Publications (2)

Publication Number	Publication Date
NO136574B NO136574B (en)	1977-06-20
NO136574C true NO136574C (en)	1977-09-28

Family

ID=22715935

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO3686/72A NO136574C (en)	1971-10-29	1972-10-13	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE PYRIMIDINE DERIVATIVES.

Country Status (25)

Country	Link
JP (2)	JPS5337870B2 (en)
AR (2)	AR198798A1 (en)
AT (2)	AT321308B (en)
AU (1)	AU467600B2 (en)
BE (1)	BE790125A (en)
CA (1)	CA980778A (en)
CH (2)	CH555832A (en)
DE (3)	DE2248741C3 (en)
DK (1)	DK131465B (en)
EG (1)	EG11013A (en)
ES (2)	ES407730A1 (en)
FI (1)	FI55503C (en)
FR (1)	FR2157865B1 (en)
GB (2)	GB1377720A (en)
IE (1)	IE37043B1 (en)
IL (2)	IL40458A (en)
LU (1)	LU66304A1 (en)
NL (1)	NL166470C (en)
NO (1)	NO136574C (en)
PH (2)	PH10129A (en)
PL (2)	PL84634B1 (en)
SE (2)	SE393376B (en)
SU (2)	SU498908A3 (en)
YU (2)	YU35125B (en)
ZA (1)	ZA727362B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS55151912U (en) *	1979-04-17	1980-11-01
DE3222914A1 (en) *	1982-06-18	1983-12-22	Beiersdorf Ag, 2000 Hamburg	SUBSTITUTED 5-PHENYLTHIO-6-AMINO-PYRIMIDINONE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE, AND PREPARATIONS CONTAINING THESE COMPOUNDS
JPH0655686B2 (en) *	1988-08-30	1994-07-27	宇部興産株式会社	Process for producing p-bromophenoxyacetaldehyde dialkyl acetals
KR101577554B1 (en)	2005-08-22	2015-12-14	멜리어 파마슈티칼스 아이, 인코포레이티드	Methods and formulations for modulating lyn kinase activity and treating related disorders
US8552184B2 (en)	2008-07-03	2013-10-08	Melior Pharmaceuticals I, Inc.	Compounds and methods for treating disorders related to glucose metabolism
WO2011150300A1 (en)	2010-05-28	2011-12-01	Melior Pharmaceuticals I, Inc.	Prevention of pancreatic beta cell degeneration
AU2018250795B2 (en)	2017-04-10	2022-02-10	Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College	Treatment of adipocytes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2913462A (en) *		1959-11-17		Eahl h
GB951431A (en) *	1959-03-17	1964-03-04	Wellcome Found	Pyrimidine derivatives and the manufacture thereof

0
- BE BE790125D patent/BE790125A/en not_active IP Right Cessation
1972
- 1972-02-18 GB GB5005373A patent/GB1377720A/en not_active Expired
- 1972-02-18 GB GB774872A patent/GB1377308A/en not_active Expired
- 1972-09-25 SE SE7212358A patent/SE393376B/en unknown
- 1972-09-28 IL IL40458A patent/IL40458A/en unknown
- 1972-09-28 AU AU47228/72A patent/AU467600B2/en not_active Expired
- 1972-10-02 PH PH13959A patent/PH10129A/en unknown
- 1972-10-05 DE DE2248741A patent/DE2248741C3/en not_active Expired
- 1972-10-05 DE DE2264374A patent/DE2264374C3/en not_active Expired
- 1972-10-05 DE DE2264657A patent/DE2264657C2/en not_active Expired
- 1972-10-06 AT AT858972A patent/AT321308B/en not_active IP Right Cessation
- 1972-10-06 AT AT00933/74A patent/AT320656B/en not_active IP Right Cessation
- 1972-10-12 FI FI2825/72A patent/FI55503C/en active
- 1972-10-12 YU YU2551/72A patent/YU35125B/en unknown
- 1972-10-13 SU SU1839308A patent/SU498908A3/en active
- 1972-10-13 NO NO3686/72A patent/NO136574C/en unknown
- 1972-10-16 IE IE1398/72A patent/IE37043B1/en unknown
- 1972-10-16 CH CH1507872A patent/CH555832A/en not_active IP Right Cessation
- 1972-10-16 NL NL7213959.A patent/NL166470C/en not_active IP Right Cessation
- 1972-10-16 PL PL1972158297A patent/PL84634B1/pl unknown
- 1972-10-16 FR FR7236560A patent/FR2157865B1/fr not_active Expired
- 1972-10-16 LU LU66304A patent/LU66304A1/xx unknown
- 1972-10-16 JP JP10279972A patent/JPS5337870B2/ja not_active Expired
- 1972-10-16 CH CH165674A patent/CH549579A/en not_active IP Right Cessation
- 1972-10-16 DK DK510072AA patent/DK131465B/en not_active IP Right Cessation
- 1972-10-16 PL PL1972174103A patent/PL89852B1/pl unknown
- 1972-10-16 ZA ZA727362A patent/ZA727362B/en unknown
- 1972-10-16 CA CA153,956A patent/CA980778A/en not_active Expired
- 1972-10-18 ES ES407730A patent/ES407730A1/en not_active Expired
- 1972-10-19 EG EG431/72A patent/EG11013A/en active
- 1972-10-23 AR AR244763A patent/AR198798A1/en active
1973
- 1973-07-12 AR AR249053A patent/AR196263A1/en active
1974
- 1974-03-26 SU SU2008490A patent/SU505362A3/en active
1975
- 1975-04-15 ES ES436624A patent/ES436624A1/en not_active Expired
- 1975-05-06 SE SE7505279A patent/SE397090B/en unknown
- 1975-11-21 PH PH17784A patent/PH11594A/en unknown
1976
- 1976-01-05 IL IL48790A patent/IL48790A/en unknown
1978
- 1978-02-08 JP JP1336078A patent/JPS53116386A/en active Granted
1979
- 1979-04-25 YU YU991/79A patent/YU36295B/en unknown

Also Published As

Publication number	Publication date
JPS53116386A (en)	1978-10-11
IE37043B1 (en)	1977-04-27
IL48790A (en)	1976-05-31
DE2248741B2 (en)	1974-11-14
DK131465B (en)	1975-07-21
SE393376B (en)	1977-05-09
NL166470C (en)	1981-08-17
IL40458A (en)	1976-05-31
DE2264657A1 (en)	1974-06-20
SU498908A3 (en)	1976-01-05
JPS4852780A (en)	1973-07-24
AT321308B (en)	1975-03-25
GB1377308A (en)	1974-12-11
BE790125A (en)	1973-04-16
GB1377720A (en)	1974-12-18
AT320656B (en)	1975-02-25
PL84634B1 (en)	1976-04-30
ES407730A1 (en)	1976-01-16
FR2157865B1 (en)	1975-10-31
YU99179A (en)	1981-08-31
YU36295B (en)	1982-06-18
NL7213959A (en)	1973-05-02
DE2264657C2 (en)	1982-09-16
SE397090B (en)	1977-10-17
DK131465C (en)	1975-12-08
CH549579A (en)	1974-05-31
FI55503C (en)	1979-08-10
DE2248741A1 (en)	1973-05-03
JPS5422995B2 (en)	1979-08-10
PL89852B1 (en)	1976-12-31
CA980778A (en)	1975-12-30
DE2264374A1 (en)	1973-05-24
YU35125B (en)	1980-09-25
NL166470B (en)	1981-03-16
YU255172A (en)	1980-03-15
ZA727362B (en)	1973-11-28
IL48790A0 (en)	1976-03-31
DE2264374C3 (en)	1981-07-23
AR196263A1 (en)	1973-12-10
LU66304A1 (en)	1973-05-03
SE7505279L (en)	1975-05-06
IE37043L (en)	1973-04-29
PH10129A (en)	1976-09-02
SU505362A3 (en)	1976-02-28
CH555832A (en)	1974-11-15
NO136574B (en)	1977-06-20
PH11594A (en)	1978-03-31
JPS5337870B2 (en)	1978-10-12
IL40458A0 (en)	1972-11-28
DE2248741C3 (en)	1975-06-26
AU4722872A (en)	1974-04-04
AU467600B2 (en)	1975-12-04
ES436624A1 (en)	1977-02-01
FI55503B (en)	1979-04-30
FR2157865A1 (en)	1973-06-08
AR198798A1 (en)	1974-07-24
EG11013A (en)	1976-11-30
DE2264374B2 (en)	1980-08-07

Publication	Publication Date	Title
NO136837C (en)	1977-11-16	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE PLEUROMUTILINES
NO138805C (en)	1978-11-15	ANALOGICAL PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE TRIAZOLE COMPOUNDS
NO139560C (en)	1979-04-04	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY EFFECTIVE NONAPEPTIDAMIDE DERIVATIVES
NO140301C (en)	1979-08-08	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE IMIDAZO (5,1-F) -AS-TRIAZINES
NO140381C (en)	1979-08-22	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE ARYLPIPERAZINES
NO136298C (en)	1977-08-17	ANALOGICAL PROCEDURE FOR THE PREPARATION OF ANTIBACTERIAL ACTIVE IMIDAZOLE DERIVATIVES
NO138565C (en)	1978-09-27	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE PIPERAZINYL-PROPYL-1,2,4-TRIAZOLINON DERIVATIVES
NO136094C (en)	1977-07-20	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE D-1- (4-AMINO-PHENYL) -2-ALKYLAMINO-ETHANOL DERIVATIVES.
NO136045C (en)	1977-07-13	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE PYRIDAZINONES.
NO137694C (en)	1978-04-05	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE BENZOMORPHANS
NO140058C (en)	1979-07-04	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE SUBSTITUTED PIPERIDINOALCANOL-OXIM DERIVATIVES
NO138999C (en)	1978-12-20	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE DIPHENYLYL-ALKANOYLAMINOPYRIDINES
NO136251C (en)	1977-08-10	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE PYRIDAZINE DERIVATIVES.
SE396388B (en)	1977-09-19	ANALOGICAL PREPARATION FOR THE PREPARATION OF 2,3-DIHYDRO-OXO-IMIDAZO- / 1,2-A / PYRIMIDINES
NO137858C (en)	1978-05-10	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE INDANONS
SE400551B (en)	1978-04-03	PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 3-AMINO-5-CARBAMYLBENZOIC ACID DERIVATIVES
FI49827C (en)	1975-10-10	Process for the preparation of therapeutically active substituted 3-hydroxymethylisoquinolines.
NO136574C (en)	1977-09-28	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE PYRIMIDINE DERIVATIVES.
NO137728C (en)	1978-04-12	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE PYRASI-4-OXYDE DERIVATIVES
NO136841C (en)	1977-11-16	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE PHENYLIMIDAZOLIDINONES
NO137696C (en)	1978-04-05	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE BENZODIAZEPINE DERIVATIVES
NO137727C (en)	1978-04-12	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE 1-PHENYL-3-HYDROXY-3-METHYLTRIAZENES
NO137695C (en)	1978-04-05	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE N-THENYLMETHYL-HETEROCYCLIC COMPOUNDS
NO139440C (en)	1979-03-14	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE 2-AMINO-4H-PYRANES
NO136977C (en)	1977-12-07	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE OXSAZOLIDINES