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NL990039I2 - Antibacterial preparation and a 7-Ä (Z) -2- (etherified oxyimino) -2- (2-aminothiazol-4-yl) -acetamido-3-ammoniomethyl-3-cephem-4-carboxylic acid derivative suitable for use in this preparation . - Google Patents

Antibacterial preparation and a 7-Ä (Z) -2- (etherified oxyimino) -2- (2-aminothiazol-4-yl) -acetamido-3-ammoniomethyl-3-cephem-4-carboxylic acid derivative suitable for use in this preparation .

Info

Publication number
NL990039I2
NL990039I2 NL990039C NL990039C NL990039I2 NL 990039 I2 NL990039 I2 NL 990039I2 NL 990039 C NL990039 C NL 990039C NL 990039 C NL990039 C NL 990039C NL 990039 I2 NL990039 I2 NL 990039I2
Authority
NL
Netherlands
Prior art keywords
preparation
ammoniomethyl
aminothiazol
cephem
acetamido
Prior art date
Application number
NL990039C
Other languages
Dutch (nl)
Other versions
NL990039I1 (en
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/354,851 external-priority patent/US4406899A/en
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NL990039I1 publication Critical patent/NL990039I1/en
Publication of NL990039I2 publication Critical patent/NL990039I2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL990039C 1982-03-04 1999-11-05 Antibacterial preparation and a 7-Ä (Z) -2- (etherified oxyimino) -2- (2-aminothiazol-4-yl) -acetamido-3-ammoniomethyl-3-cephem-4-carboxylic acid derivative suitable for use in this preparation . NL990039I2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/354,851 US4406899A (en) 1982-03-04 1982-03-04 Cephalosporins
US35753482A 1982-03-12 1982-03-12

Publications (2)

Publication Number Publication Date
NL990039I1 NL990039I1 (en) 2000-01-03
NL990039I2 true NL990039I2 (en) 2000-04-03

Family

ID=26998584

Family Applications (2)

Application Number Title Priority Date Filing Date
NL8300755A NL193284C (en) 1982-03-04 1983-03-01 Antibacterial preparation and a 7 - [(Z) -2- (etherified oxyimino) -2- (2-aminothiazol-4-yl) -acetamido] -3-ammoniomethyl-3-cephem-4-carboxylic acid suitable for use in this preparation derivative.
NL990039C NL990039I2 (en) 1982-03-04 1999-11-05 Antibacterial preparation and a 7-Ä (Z) -2- (etherified oxyimino) -2- (2-aminothiazol-4-yl) -acetamido-3-ammoniomethyl-3-cephem-4-carboxylic acid derivative suitable for use in this preparation .

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NL8300755A NL193284C (en) 1982-03-04 1983-03-01 Antibacterial preparation and a 7 - [(Z) -2- (etherified oxyimino) -2- (2-aminothiazol-4-yl) -acetamido] -3-ammoniomethyl-3-cephem-4-carboxylic acid suitable for use in this preparation derivative.

Country Status (29)

Country Link
KR (1) KR870001986B1 (en)
AT (2) AT382155B (en)
AU (1) AU562776B2 (en)
BE (1) BE896086A (en)
CA (1) CA1213882A (en)
CH (1) CH654313A5 (en)
CS (1) CS249512B2 (en)
DD (1) DD210280A5 (en)
DE (1) DE3307550A1 (en)
DK (1) DK156900C (en)
EG (1) EG15934A (en)
ES (2) ES8403919A1 (en)
FI (1) FI74973C (en)
FR (1) FR2522659B1 (en)
GB (1) GB2116180B (en)
GR (1) GR77916B (en)
HU (1) HU193158B (en)
IE (1) IE56647B1 (en)
IL (1) IL68011A0 (en)
IT (1) IT1170307B (en)
LU (1) LU84674A1 (en)
MY (1) MY8700943A (en)
NL (2) NL193284C (en)
NZ (1) NZ203312A (en)
PH (1) PH18002A (en)
PT (1) PT76330B (en)
SE (1) SE453091B (en)
SU (1) SU1250173A3 (en)
YU (2) YU43822B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3409431A1 (en) * 1983-10-08 1985-04-18 Hoechst Ag, 6230 Frankfurt CEPHALOSPORINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION
DE3404906A1 (en) * 1984-02-11 1985-08-14 Bayer Ag, 5090 Leverkusen 1-OXADETHIACEPHALOSPORINE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
DE3419013A1 (en) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen NEW CEPHALOSPORINE AND METHOD FOR THEIR PRODUCTION
GB8424692D0 (en) * 1984-10-01 1984-11-07 Glaxo Group Ltd Chemical compounds
US4698336A (en) * 1985-01-30 1987-10-06 Eisai Co., Ltd. 3-(pyrrolidinio)methyl-3-cephem derivatives
FR2585705B1 (en) * 1985-08-05 1989-01-13 Bristol Myers Co CEPHALOSPORIN SALTS AND INJECTABLE COMPOSITIONS
US4910301A (en) * 1985-08-05 1990-03-20 Bristol-Myers Company Cefepime cephalosporin salts
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
EP0237735B1 (en) * 1986-03-17 1994-03-30 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituted-3-cephem compounds and process for production of the same
CA2011116C (en) * 1989-03-06 1999-11-16 Murray A. Kaplan Lyophilized bmy-28142 dihydrochloride for parenteral use
EP0503453B1 (en) 1991-03-08 2001-05-09 Biochemie Gesellschaft M.B.H. New process for the production of cephalosporines and novel intermediates in this process
YU81692A (en) * 1991-09-10 1995-03-27 Bristol-Myers Co. PROCEDURE FOR THE PRODUCTION OF CEPHALOSPORIN ANTIBIOTICS
IL103110A (en) * 1991-09-10 1997-04-15 Bristol Myers Squibb Co Anhydrous process for preparing cefepime dihydrochloride hydrate
US5523400A (en) * 1993-04-16 1996-06-04 Hoffmann-La Roche Inc. Cephalosporin antibiotics
DE602004011685T2 (en) * 2003-12-23 2009-02-05 Sandoz Gmbh PROCESS FOR PREPARING INTERMEDIATE PRODUCTS FOR USE IN THE CEFALOSPORIN SYNTHESIS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins
GB1591439A (en) * 1976-10-01 1981-06-24 Glaxo Operations Ltd 7-syn (oxyimino -acylamido) cephalosporins
AR228726A1 (en) * 1978-05-26 1983-04-15 Glaxo Group Ltd PROCEDURE FOR THE PREPARATION OF ANTIBIOTIC (6R, 7R) -7 - ((Z) -2- (2-AMINOTIAZOL-4-IL) -2- (2-CARBOXIPROP-2-OXIIMINO) ACETAMIDO) -3- (1- PIRIDINIOMETIL) CEF-3-EM-4-CARBOXILATO
SE7908895L (en) * 1978-10-27 1980-04-28 Glaxo Group Ltd cephalosporin
US4443444A (en) * 1980-08-11 1984-04-17 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds

Also Published As

Publication number Publication date
NL193284B (en) 1999-01-04
KR870001986B1 (en) 1987-10-24
GR77916B (en) 1984-09-25
FR2522659B1 (en) 1986-10-24
NZ203312A (en) 1985-12-13
FR2522659A1 (en) 1983-09-09
CH654313A5 (en) 1986-02-14
NL193284C (en) 1999-05-06
SE8301178L (en) 1983-09-05
DE3307550A1 (en) 1983-09-15
BE896086A (en) 1983-09-05
ES520224A0 (en) 1984-04-01
DK86283A (en) 1983-09-05
DD210280A5 (en) 1984-06-06
YU52383A (en) 1986-02-28
SU1250173A3 (en) 1986-08-07
KR840004118A (en) 1984-10-06
AT382155B (en) 1987-01-26
IE830455L (en) 1983-09-04
LU84674A1 (en) 1983-11-17
YU149685A (en) 1986-02-28
FI74973B (en) 1987-12-31
GB2116180A (en) 1983-09-21
FI830689L (en) 1983-09-05
SE453091B (en) 1988-01-11
YU44777B (en) 1991-02-28
DE3307550C2 (en) 1988-11-24
ATA228285A (en) 1987-05-15
PH18002A (en) 1985-02-28
FI830689A0 (en) 1983-03-01
NL990039I1 (en) 2000-01-03
ATA76183A (en) 1986-06-15
CS249512B2 (en) 1987-03-12
YU43822B (en) 1989-12-31
EG15934A (en) 1987-10-30
PT76330B (en) 1986-02-04
ES8403919A1 (en) 1984-04-01
NL8300755A (en) 1983-10-03
IL68011A0 (en) 1983-06-15
HU193158B (en) 1987-08-28
GB2116180B (en) 1985-09-18
FI74973C (en) 1988-04-11
SE8301178D0 (en) 1983-03-03
IT1170307B (en) 1987-06-03
IE56647B1 (en) 1991-10-23
GB8305940D0 (en) 1983-04-07
DK156900C (en) 1990-03-12
IT8347826A0 (en) 1983-03-01
ES526397A0 (en) 1985-09-16
ES8507557A1 (en) 1985-09-16
DK86283D0 (en) 1983-02-24
DK156900B (en) 1989-10-16
AU1130483A (en) 1983-09-08
CA1213882A (en) 1986-11-12
MY8700943A (en) 1987-12-31
PT76330A (en) 1983-04-01
AT384612B (en) 1987-12-10
AU562776B2 (en) 1987-06-18

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