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NL970024I2 - Anti-tumor middelen. - Google Patents

Anti-tumor middelen.

Info

Publication number
NL970024I2
NL970024I2 NL970024C NL970024C NL970024I2 NL 970024 I2 NL970024 I2 NL 970024I2 NL 970024 C NL970024 C NL 970024C NL 970024 C NL970024 C NL 970024C NL 970024 I2 NL970024 I2 NL 970024I2
Authority
NL
Netherlands
Prior art keywords
tumor agents
tumor
agents
Prior art date
Application number
NL970024C
Other languages
English (en)
Other versions
NL970024I1 (nl
Original Assignee
British Tech Group
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Tech Group, Zeneca Ltd filed Critical British Tech Group
Publication of NL970024I1 publication Critical patent/NL970024I1/nl
Publication of NL970024I2 publication Critical patent/NL970024I2/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms
    • C07D239/90Oxygen atoms with acyclic radicals attached in position 2 or 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NL970024C 1986-03-27 1997-07-07 Anti-tumor middelen. NL970024I2 (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868607683A GB8607683D0 (en) 1986-03-27 1986-03-27 Anti-tumor agents

Publications (2)

Publication Number Publication Date
NL970024I1 NL970024I1 (nl) 1997-09-01
NL970024I2 true NL970024I2 (nl) 1997-10-01

Family

ID=10595358

Family Applications (1)

Application Number Title Priority Date Filing Date
NL970024C NL970024I2 (nl) 1986-03-27 1997-07-07 Anti-tumor middelen.

Country Status (22)

Country Link
US (2) US4992550A (nl)
EP (1) EP0239362B1 (nl)
JP (1) JPH0657699B2 (nl)
AR (1) AR244213A1 (nl)
AT (1) ATE70057T1 (nl)
AU (1) AU592628B2 (nl)
CA (1) CA1285943C (nl)
DE (1) DE3774909D1 (nl)
DK (1) DK166621B1 (nl)
ES (1) ES2038170T3 (nl)
FI (1) FI89912C (nl)
GB (2) GB8607683D0 (nl)
GR (1) GR3003282T3 (nl)
HK (1) HK8594A (nl)
HU (1) HU197317B (nl)
IE (1) IE60302B1 (nl)
IL (1) IL81924A (nl)
LU (1) LU88797I2 (nl)
NL (1) NL970024I2 (nl)
NO (2) NO173545C (nl)
PT (1) PT84571B (nl)
ZA (1) ZA871998B (nl)

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US5286726A (en) * 1990-04-12 1994-02-15 The Regents Of The University Of Michigan Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
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Also Published As

Publication number Publication date
EP0239362A2 (en) 1987-09-30
CA1285943C (en) 1991-07-09
EP0239362B1 (en) 1991-12-04
DK166621B1 (da) 1993-06-21
AU7047287A (en) 1987-10-01
ES2038170T3 (es) 1993-07-16
DE3774909D1 (de) 1992-01-16
JPH01125373A (ja) 1989-05-17
PT84571B (pt) 1989-11-30
ATE70057T1 (de) 1991-12-15
FI871139A7 (fi) 1987-09-28
JPH0657699B2 (ja) 1994-08-03
NO871266L (no) 1987-09-28
IE60302B1 (en) 1994-06-29
NL970024I1 (nl) 1997-09-01
AU592628B2 (en) 1990-01-18
NO1998020I1 (no) 1998-09-28
NO871266D0 (no) 1987-03-26
LU88797I2 (fr) 1996-11-05
GB8607683D0 (en) 1986-04-30
NO173545C (no) 1993-12-29
DK155087A (da) 1987-09-28
GB2188319B (en) 1989-12-13
HUT43835A (en) 1987-12-28
US5081124A (en) 1992-01-14
GR3003282T3 (en) 1993-02-17
FI89912C (fi) 1993-12-10
DK155087D0 (da) 1987-03-26
IE870699L (en) 1987-09-27
IL81924A (en) 1991-07-18
NO173545B (no) 1993-09-20
HU197317B (en) 1989-03-28
GB2188319A (en) 1987-09-30
FI871139A0 (fi) 1987-03-16
ZA871998B (en) 1987-11-25
US4992550A (en) 1991-02-12
AR244213A1 (es) 1993-10-29
GB8706948D0 (en) 1987-04-29
EP0239362A3 (en) 1989-07-05
PT84571A (en) 1987-04-01
HK8594A (en) 1994-02-04
FI89912B (fi) 1993-08-31

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