NL8601960A - Inrichting met gecontroleerde afgifte voor het toedienen van een heilzaam middel aan een ontvanger. - Google Patents

Inrichting met gecontroleerde afgifte voor het toedienen van een heilzaam middel aan een ontvanger. Download PDF

Info

Publication number: NL8601960A
Authority: NL; Netherlands
Prior art keywords: cellulose; beneficial agent; delivery device; wall; delivering
Prior art date: 1985-08-07

Application number

NL8601960A

Other languages

English (en)

Dutch (nl)

Original Assignee

Alza Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-08-07

Filing date

1986-07-30

Publication date

1987-03-02

1986-07-30 Application filed by Alza Corp filed Critical Alza Corp

1987-03-02 Publication of NL8601960A publication Critical patent/NL8601960A/nl

Links

239000000203 mixture Substances 0.000 claims description 138
239000003795 chemical substances by application Substances 0.000 claims description 123
230000009286 beneficial effect Effects 0.000 claims description 96
229920000642 polymer Polymers 0.000 claims description 57
229920002678 cellulose Polymers 0.000 claims description 45
239000001913 cellulose Substances 0.000 claims description 37
238000009472 formulation Methods 0.000 claims description 30
239000011148 porous material Substances 0.000 claims description 30
-1 fatty acid esters Chemical class 0.000 claims description 29
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 24
229920002301 cellulose acetate Polymers 0.000 claims description 16
239000011780 sodium chloride Substances 0.000 claims description 12
229920002125 Sokalan® Polymers 0.000 claims description 11
229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 10
229920006217 cellulose acetate butyrate Polymers 0.000 claims description 9
239000000017 hydrogel Substances 0.000 claims description 9
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 7
IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims description 6
DQEFEBPAPFSJLV-UHFFFAOYSA-N Cellulose propionate Chemical compound CCC(=O)OCC1OC(OC(=O)CC)C(OC(=O)CC)C(OC(=O)CC)C1OC1C(OC(=O)CC)C(OC(=O)CC)C(OC(=O)CC)C(COC(=O)CC)O1 DQEFEBPAPFSJLV-UHFFFAOYSA-N 0.000 claims description 5
229920006218 cellulose propionate Polymers 0.000 claims description 5
150000005690 diesters Chemical class 0.000 claims description 5
229920002554 vinyl polymer Polymers 0.000 claims description 5
ODIGIKRIUKFKHP-UHFFFAOYSA-N (n-propan-2-yloxycarbonylanilino) acetate Chemical compound CC(C)OC(=O)N(OC(C)=O)C1=CC=CC=C1 ODIGIKRIUKFKHP-UHFFFAOYSA-N 0.000 claims description 4
WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 4
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235000014113 dietary fatty acids Nutrition 0.000 claims description 4
229930195729 fatty acid Natural products 0.000 claims description 4
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UGZICOVULPINFH-UHFFFAOYSA-N acetic acid;butanoic acid Chemical compound CC(O)=O.CCCC(O)=O UGZICOVULPINFH-UHFFFAOYSA-N 0.000 claims 1
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WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 6
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CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 description 6
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FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 5
FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 5
XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 5
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229940124447 delivery agent Drugs 0.000 description 5
238000005553 drilling Methods 0.000 description 5
239000008172 hydrogenated vegetable oil Substances 0.000 description 5
239000000600 sorbitol Substances 0.000 description 5
235000010356 sorbitol Nutrition 0.000 description 5
230000001225 therapeutic effect Effects 0.000 description 5
ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 description 4
LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 4
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 4
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UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0068—Rumen, e.g. rumen bolus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/249921—Web or sheet containing structurally defined element or component
- Y10T428/249994—Composite having a component wherein a constituent is liquid or is contained within preformed walls [e.g., impregnant-filled, previously void containing component, etc.]

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Physiology (AREA)
Nutrition Science (AREA)
Anesthesiology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Medicinal Preparation (AREA)
Media Introduction/Drainage Providing Device (AREA)

NL8601960A 1985-08-07 1986-07-30 Inrichting met gecontroleerde afgifte voor het toedienen van een heilzaam middel aan een ontvanger. NL8601960A (nl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/763,365 US4692336A (en)	1984-03-19	1985-08-07	Self controlled release device for administering beneficial agent to recipient
US76336585		1985-08-07

Publications (1)

Publication Number	Publication Date
NL8601960A true NL8601960A (nl)	1987-03-02

Family

ID=25067630

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL8601960A NL8601960A (nl)	1985-08-07	1986-07-30	Inrichting met gecontroleerde afgifte voor het toedienen van een heilzaam middel aan een ontvanger.

Country Status (14)

Country	Link
US (1)	US4692336A (es)
JP (1)	JPS6234576A (es)
AU (1)	AU585775B2 (es)
BE (1)	BE905214A (es)
BR (1)	BR8603651A (es)
CA (1)	CA1244738A (es)
DE (1)	DE3625854C2 (es)
ES (1)	ES8802112A1 (es)
FR (1)	FR2585949B1 (es)
GB (1)	GB2178656B (es)
IT (1)	IT1195817B (es)
NL (1)	NL8601960A (es)
NZ (1)	NZ216966A (es)
ZA (1)	ZA865827B (es)

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US4874388A (en) *	1987-06-25	1989-10-17	Alza Corporation	Multi-layer delivery system
GB2206046B (en) *	1987-06-25	1991-04-03	Alza Corp	Multi-unit delivery system
US5277915A (en) *	1987-10-30	1994-01-11	Fmc Corporation	Gel-in-matrix containing a fractured hydrogel
US4830855A (en) *	1987-11-13	1989-05-16	Landec Labs, Inc.	Temperature-controlled active agent dispenser
US4968539A (en) *	1987-12-01	1990-11-06	Lion Corporation	Liquid crystal membrane
US4959218A (en) *	1988-03-25	1990-09-25	Alza Corporation	Method for delivering somatotropin to an animal
US5034229A (en) *	1988-12-13	1991-07-23	Alza Corporation	Dispenser for increasing feed conversion of hog
US5728088A (en) *	1988-12-13	1998-03-17	Alza Corporation	Osmotic system for delivery of fluid-sensitive somatotropins to bovine animals
EP0388480A1 (de) *	1989-03-20	1990-09-26	Siemens Aktiengesellschaft	Implantierbare Reizelektrode
US5223266A (en) *	1990-01-24	1993-06-29	Alza Corporation	Long-term delivery device with early startup
US5833665A (en) *	1990-06-14	1998-11-10	Integra Lifesciences I, Ltd.	Polyurethane-biopolymer composite
US5443459A (en) *	1991-01-30	1995-08-22	Alza Corporation	Osmotic device for delayed delivery of agent
US5378475A (en) *	1991-02-21	1995-01-03	University Of Kentucky Research Foundation	Sustained release drug delivery devices
US5302397A (en) *	1991-11-19	1994-04-12	Amsden Brian G	Polymer-based drug delivery system
US5417983A (en) *	1992-02-19	1995-05-23	Sagami Chemical Research Center	Drug release controlling material responsive to changes in temperature
US5609885A (en) *	1992-09-15	1997-03-11	Alza Corporation	Osmotic membrane and delivery device
DE4431653C2 (de) *	1994-09-06	2000-01-20	Lohmann Therapie Syst Lts	Manteltablette zur kontrollierten Freisetzung von Wirkstoffen, ein Verfahren zu ihrer Herstellung und ihre Verwendung
US5607696A (en) *	1995-02-10	1997-03-04	Alza Corporation	Osmotic membrane and delivery device
US5690952A (en) *	1995-06-07	1997-11-25	Judy A. Magruder et al.	Implantable system for delivery of fluid-sensitive agents to animals
US5902598A (en) *	1997-08-28	1999-05-11	Control Delivery Systems, Inc.	Sustained release drug delivery devices
US6099859A (en)	1998-03-20	2000-08-08	Andrx Pharmaceuticals, Inc.	Controlled release oral tablet having a unitary core
US6099862A (en) *	1998-08-31	2000-08-08	Andrx Corporation	Oral dosage form for the controlled release of a biguanide and sulfonylurea
US20040121014A1 (en) *	1999-03-22	2004-06-24	Control Delivery Systems, Inc.	Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6217895B1 (en)	1999-03-22	2001-04-17	Control Delivery Systems	Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6479066B1 (en) *	1999-12-16	2002-11-12	Rst Implanted Cell Technology, Llc	Device having a microporous membrane lined deformable wall for implanting cell cultures
GB0003424D0 (en) *	2000-02-16	2000-04-05	Bioprogress Tech Int Inc	A controlled release capsule
GB2398499B (en) *	2000-02-16	2004-11-24	Bioprogress Technology Ltd	Two layer capsules
US6375972B1 (en)	2000-04-26	2002-04-23	Control Delivery Systems, Inc.	Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
US6790459B1 (en)	2000-11-03	2004-09-14	Andrx Labs, Llc	Methods for treating diabetes via administration of controlled release metformin
US6866866B1 (en) *	2000-11-03	2005-03-15	Andrx Labs, Llc	Controlled release metformin compositions
US20060034922A1 (en) *	2000-11-03	2006-02-16	Andrx Labs, Llc	Controlled release metformin compositions
EP1424957A2 (en)	2001-09-14	2004-06-09	Francis J. Martin	Microfabricated nanopore device for sustained release of therapeutic agent
WO2003051341A1 (en) *	2001-12-18	2003-06-26	Alza Corporation	Dosage form for providing time-varying patterns of drug delivery
DE10220126B4 (de) *	2002-05-06	2008-01-03	Siemens Ag	Vorrichtung zur Befestigung von Initiatoren und Sensoren
US8871241B2 (en)	2002-05-07	2014-10-28	Psivida Us, Inc.	Injectable sustained release delivery devices
US20040052848A1 (en) *	2002-05-23	2004-03-18	Xiu-Xiu Cheng	Biguanide formulations
US8062254B2 (en)	2008-01-08	2011-11-22	MacLean, LLC	Spring driven adjustable oral syringe
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WO2020139896A1 (en) *	2018-12-28	2020-07-02	Mott Corporation	Devices, systems and methods for an implantable drug delivery device

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US4034756A (en) *	1971-01-13	1977-07-12	Alza Corporation	Osmotically driven fluid dispenser
US3760804A (en) *	1971-01-13	1973-09-25	Alza Corp	Improved osmotic dispenser employing magnesium sulphate and magnesium chloride
US3732865A (en) *	1971-01-13	1973-05-15	Alza Corp	Osmotic dispenser
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US4160452A (en) *	1977-04-07	1979-07-10	Alza Corporation	Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina
DE2729068A1 (de) *	1977-06-28	1979-01-11	Rainer Dr Med Liedtke	Verfahren zur freisetzungssteuerung von arzneimitteln aus kapseln
US4196187A (en) *	1977-09-02	1980-04-01	Eastman Kodak Company	Rumen-stable pellets
US4285987A (en) *	1978-10-23	1981-08-25	Alza Corporation	Process for manufacturing device with dispersion zone
US4200098A (en) *	1978-10-23	1980-04-29	Alza Corporation	Osmotic system with distribution zone for dispensing beneficial agent
US4235236A (en) *	1979-02-12	1980-11-25	Alza Corporation	Device for dispensing drug by combined diffusional and osmotic operations
US4320759A (en) *	1980-04-28	1982-03-23	Alza Corporation	Dispenser with diffuser
US4595583A (en) *	1984-03-19	1986-06-17	Alza Corporation	Delivery system controlled administration of beneficial agent to ruminants
JPS6437367A (en) *	1987-07-21	1989-02-08	Taiyo Yuden Kk	Cover tape for part receiving strip

1985
- 1985-08-07 US US06/763,365 patent/US4692336A/en not_active Expired - Lifetime
1986
- 1986-06-17 ES ES556147A patent/ES8802112A1/es not_active Expired
- 1986-07-22 GB GB8617905A patent/GB2178656B/en not_active Expired
- 1986-07-25 NZ NZ216966A patent/NZ216966A/xx unknown
- 1986-07-28 AU AU60614/86A patent/AU585775B2/en not_active Expired
- 1986-07-28 JP JP61177490A patent/JPS6234576A/ja active Pending
- 1986-07-30 NL NL8601960A patent/NL8601960A/nl active Search and Examination
- 1986-07-30 DE DE3625854A patent/DE3625854C2/de not_active Expired - Lifetime
- 1986-07-30 CA CA000514924A patent/CA1244738A/en not_active Expired
- 1986-08-01 BR BR8603651A patent/BR8603651A/pt not_active IP Right Cessation
- 1986-08-04 ZA ZA865827A patent/ZA865827B/xx unknown
- 1986-08-04 BE BE0/217005A patent/BE905214A/fr not_active IP Right Cessation
- 1986-08-06 FR FR868611369A patent/FR2585949B1/fr not_active Expired
- 1986-08-06 IT IT67635/86A patent/IT1195817B/it active

Also Published As

Publication number	Publication date
FR2585949B1 (fr)	1989-03-03
AU585775B2 (en)	1989-06-22
IT8667635A0 (it)	1986-08-06
JPS6234576A (ja)	1987-02-14
NZ216966A (en)	1989-09-27
ZA865827B (en)	1987-04-29
IT8667635A1 (it)	1988-02-06
CA1244738A (en)	1988-11-15
GB8617905D0 (en)	1986-08-28
GB2178656A (en)	1987-02-18
FR2585949A1 (fr)	1987-02-13
IT1195817B (it)	1988-10-27
DE3625854A1 (de)	1987-02-19
ES8802112A1 (es)	1988-04-01
DE3625854C2 (de)	1998-04-09
ES556147A0 (es)	1988-04-01
BE905214A (fr)	1986-12-01
GB2178656B (en)	1989-09-06
US4692336A (en)	1987-09-08
AU6061486A (en)	1987-02-12
BR8603651A (pt)	1987-03-10

Publication	Publication Date	Title
NL8601960A (nl)	1987-03-02	Inrichting met gecontroleerde afgifte voor het toedienen van een heilzaam middel aan een ontvanger.
US4684524A (en)	1987-08-04	Rate controlled dispenser for administering beneficial agent
US4772474A (en)	1988-09-20	Dispenser with internal arrangement of lamina means for dispensing beneficial agent
US5000957A (en)	1991-03-19	Dispenser comprising hydrophilic osmopolymer
US4624945A (en)	1986-11-25	Dispensing system with means for increasing delivery of beneficial agent from the system
US4844984A (en)	1989-07-04	Dispensing system with means for increasing delivery of beneficial agent from the system
US4783337A (en)	1988-11-08	Osmotic system comprising plurality of members for dispensing drug
CA1222950A (en)	1987-06-16	Osmotic device with dual thermodynamic activity
US5324280A (en)	1994-06-28	Osmotic dosage system for delivering a formulation comprising liquid carrier and drug
US5082668A (en)	1992-01-21	Controlled-release system with constant pushing source
US4717568A (en)	1988-01-05	Laminar arrangement for increasing delivery of beneficial agent from dispenser
US4971790A (en)	1990-11-20	Dosage form for lessening irritation of mocusa
JPH0155242B2 (es)	1989-11-22
GB2155787A (en)	1985-10-02	Osmotic delivery devices
US4717718A (en)	1988-01-05	Device for the controlled delivery of a beneficial agent
GB2178956A (en)	1987-02-25	Active agent dispenser
US4883667A (en)	1989-11-28	Process for forming dispensing device
US4729793A (en)	1988-03-08	Composition for manufacturing wall of dispensing device
CA1315628C (en)	1993-04-06	System for delivering drug with enhanced bioacceptability
US4747847A (en)	1988-05-31	System for delivering potassium chloride with enhanced bioacceptability
JPH0137367B2 (es)	1989-08-07
US4927633A (en)	1990-05-22	Dispenser for delivering drug to livestock

Legal Events

Date	Code	Title
1993-03-01	BA	A request for search or an international-type search has been filed
1993-06-01	BB	A search report has been drawn up
1993-07-01	BC	A request for examination has been filed
2002-07-01	BN	A decision not to publish the application has become irrevocable