NL8000446A - Samenstellingen voor toepassing als cosmetica en werkwijze voor de bereiding van de werkzame bestand- delen daarvan. - Google Patents
Samenstellingen voor toepassing als cosmetica en werkwijze voor de bereiding van de werkzame bestand- delen daarvan. Download PDFInfo
- Publication number
- NL8000446A NL8000446A NL8000446A NL8000446A NL8000446A NL 8000446 A NL8000446 A NL 8000446A NL 8000446 A NL8000446 A NL 8000446A NL 8000446 A NL8000446 A NL 8000446A NL 8000446 A NL8000446 A NL 8000446A
- Authority
- NL
- Netherlands
- Prior art keywords
- nicotinic acid
- integer
- composition according
- general formula
- active ingredient
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims description 49
- 239000013543 active substance Substances 0.000 title claims description 11
- 238000000034 method Methods 0.000 title claims description 10
- 239000002537 cosmetic Substances 0.000 title claims description 8
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims description 83
- 235000001968 nicotinic acid Nutrition 0.000 claims description 36
- 239000011664 nicotinic acid Substances 0.000 claims description 36
- 229960003512 nicotinic acid Drugs 0.000 claims description 34
- 150000001875 compounds Chemical class 0.000 claims description 30
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 22
- 239000002253 acid Substances 0.000 claims description 17
- 239000004480 active ingredient Substances 0.000 claims description 15
- 150000002148 esters Chemical class 0.000 claims description 14
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 12
- 229910052739 hydrogen Inorganic materials 0.000 claims description 11
- 239000001257 hydrogen Substances 0.000 claims description 9
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 8
- 238000010438 heat treatment Methods 0.000 claims description 8
- -1 nicotinic acid halide Chemical class 0.000 claims description 8
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 claims description 8
- 150000001720 carbohydrates Chemical class 0.000 claims description 7
- 235000014633 carbohydrates Nutrition 0.000 claims description 7
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 6
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 6
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 6
- 229930195725 Mannitol Natural products 0.000 claims description 6
- 125000000217 alkyl group Chemical group 0.000 claims description 6
- 238000006243 chemical reaction Methods 0.000 claims description 6
- 239000000594 mannitol Substances 0.000 claims description 6
- 235000010355 mannitol Nutrition 0.000 claims description 6
- 239000000600 sorbitol Substances 0.000 claims description 6
- MSWZFWKMSRAUBD-IVMDWMLBSA-N 2-amino-2-deoxy-D-glucopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 claims description 5
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 claims description 5
- 229960002442 glucosamine Drugs 0.000 claims description 5
- 150000002431 hydrogen Chemical class 0.000 claims description 5
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims description 4
- 239000000654 additive Substances 0.000 claims description 4
- 239000003153 chemical reaction reagent Substances 0.000 claims description 4
- 229940079593 drug Drugs 0.000 claims description 4
- 239000003814 drug Substances 0.000 claims description 4
- 239000003205 fragrance Substances 0.000 claims description 4
- HEBKCHPVOIAQTA-QWWZWVQMSA-N D-arabinitol Chemical compound OC[C@@H](O)C(O)[C@H](O)CO HEBKCHPVOIAQTA-QWWZWVQMSA-N 0.000 claims description 3
- 239000002202 Polyethylene glycol Substances 0.000 claims description 3
- 239000007795 chemical reaction product Substances 0.000 claims description 3
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims description 3
- 239000012442 inert solvent Substances 0.000 claims description 3
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 3
- 229920001223 polyethylene glycol Polymers 0.000 claims description 3
- 239000012429 reaction media Substances 0.000 claims description 3
- 239000002904 solvent Substances 0.000 claims description 3
- 235000013311 vegetables Nutrition 0.000 claims description 3
- 229940088594 vitamin Drugs 0.000 claims description 3
- 235000013343 vitamin Nutrition 0.000 claims description 3
- 239000011782 vitamin Substances 0.000 claims description 3
- 229930003231 vitamin Natural products 0.000 claims description 3
- ROHQCYQEENBTEN-BTVCFUMJSA-N (2r,3r,4s,5r)-2-amino-3,4,5,6-tetrahydroxyhexanal;pyridine-3-carboxylic acid Chemical compound OC(=O)C1=CC=CN=C1.O=C[C@H](N)[C@@H](O)[C@H](O)[C@H](O)CO ROHQCYQEENBTEN-BTVCFUMJSA-N 0.000 claims description 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 2
- GZCGUPFRVQAUEE-SLPGGIOYSA-N aldehydo-D-glucose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O GZCGUPFRVQAUEE-SLPGGIOYSA-N 0.000 claims description 2
- 125000000649 benzylidene group Chemical group [H]C(=[*])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims description 2
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims description 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 2
- QDRKDTQENPPHOJ-UHFFFAOYSA-N sodium ethoxide Chemical compound [Na+].CC[O-] QDRKDTQENPPHOJ-UHFFFAOYSA-N 0.000 claims description 2
- 239000004094 surface-active agent Substances 0.000 claims description 2
- 239000003599 detergent Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000003883 ointment base Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 description 44
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 21
- CBOJBBMQJBVCMW-BTVCFUMJSA-N (2r,3r,4s,5r)-2-amino-3,4,5,6-tetrahydroxyhexanal;hydrochloride Chemical compound Cl.O=C[C@H](N)[C@@H](O)[C@H](O)[C@H](O)CO CBOJBBMQJBVCMW-BTVCFUMJSA-N 0.000 description 6
- 229960001911 glucosamine hydrochloride Drugs 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 5
- 235000000346 sugar Nutrition 0.000 description 5
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 4
- 235000007866 Chamaemelum nobile Nutrition 0.000 description 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 4
- 244000042664 Matricaria chamomilla Species 0.000 description 4
- 235000007232 Matricaria chamomilla Nutrition 0.000 description 4
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 239000007864 aqueous solution Substances 0.000 description 4
- 239000002674 ointment Substances 0.000 description 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- 239000006227 byproduct Substances 0.000 description 3
- 239000000706 filtrate Substances 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- ATBIAJXSKNPHEI-UHFFFAOYSA-N pyridine-3-carbonyl chloride Chemical compound ClC(=O)C1=CC=CN=C1 ATBIAJXSKNPHEI-UHFFFAOYSA-N 0.000 description 3
- 239000011541 reaction mixture Substances 0.000 description 3
- 210000004761 scalp Anatomy 0.000 description 3
- 239000002453 shampoo Substances 0.000 description 3
- 159000000000 sodium salts Chemical class 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 150000008163 sugars Chemical class 0.000 description 3
- 239000000606 toothpaste Substances 0.000 description 3
- VBAPJVPDLNHFAZ-SSPAHAAFSA-N (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal pyridine-3-carboxylic acid Chemical compound C(C1=CN=CC=C1)(=O)O.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO VBAPJVPDLNHFAZ-SSPAHAAFSA-N 0.000 description 2
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical class O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 230000004071 biological effect Effects 0.000 description 2
- 230000002349 favourable effect Effects 0.000 description 2
- 230000003779 hair growth Effects 0.000 description 2
- 125000004430 oxygen atom Chemical group O* 0.000 description 2
- 239000000419 plant extract Substances 0.000 description 2
- 238000007670 refining Methods 0.000 description 2
- 235000017557 sodium bicarbonate Nutrition 0.000 description 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 150000005846 sugar alcohols Chemical class 0.000 description 2
- 229940034610 toothpaste Drugs 0.000 description 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 1
- KYPWIZMAJMNPMJ-IANNHFEVSA-N (3r,5s,6r)-6-methyloxane-2,3,5-triol Chemical compound C[C@H]1OC(O)[C@H](O)C[C@@H]1O KYPWIZMAJMNPMJ-IANNHFEVSA-N 0.000 description 1
- VOQAOTALYZIMDB-UHFFFAOYSA-N 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl hydrogen sulfate Chemical compound OCCOCCOCCOCCOS(O)(=O)=O VOQAOTALYZIMDB-UHFFFAOYSA-N 0.000 description 1
- GDOCJYOSJSADCJ-UHFFFAOYSA-N 2-aminoethanol;pyridine-3-carboxylic acid Chemical compound [NH3+]CCO.[O-]C(=O)C1=CC=CN=C1 GDOCJYOSJSADCJ-UHFFFAOYSA-N 0.000 description 1
- 235000018185 Betula X alpestris Nutrition 0.000 description 1
- 235000018212 Betula X uliginosa Nutrition 0.000 description 1
- 101100228200 Caenorhabditis elegans gly-5 gene Proteins 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- GNTQICZXQYZQNE-UHFFFAOYSA-N Colitose Natural products CC(O)C(O)CC(O)C=O GNTQICZXQYZQNE-UHFFFAOYSA-N 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010020565 Hyperaemia Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 240000001090 Papaver somniferum Species 0.000 description 1
- 235000008753 Papaver somniferum Nutrition 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 239000012670 alkaline solution Substances 0.000 description 1
- 125000003277 amino group Chemical group 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 230000003851 biochemical process Effects 0.000 description 1
- 230000031018 biological processes and functions Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000012459 cleaning agent Substances 0.000 description 1
- 239000012043 crude product Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000032050 esterification Effects 0.000 description 1
- 238000005886 esterification reaction Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 229960004592 isopropanol Drugs 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- YLGXILFCIXHCMC-JHGZEJCSSA-N methyl cellulose Chemical compound COC1C(OC)C(OC)C(COC)O[C@H]1O[C@H]1C(OC)C(OC)C(OC)OC1COC YLGXILFCIXHCMC-JHGZEJCSSA-N 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 230000037368 penetrate the skin Effects 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 229920000151 polyglycol Polymers 0.000 description 1
- 239000010695 polyglycol Substances 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 235000017709 saponins Nutrition 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 229940079862 sodium lauryl sarcosinate Drugs 0.000 description 1
- ADWNFGORSPBALY-UHFFFAOYSA-M sodium;2-[dodecyl(methyl)amino]acetate Chemical compound [Na+].CCCCCCCCCCCCN(C)CC([O-])=O ADWNFGORSPBALY-UHFFFAOYSA-M 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000000304 vasodilatating effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUFE001046 | 1979-06-01 | ||
| HU79FE1046A HU184626B (en) | 1979-06-01 | 1979-06-01 | Congesting cosmetics first of all hair-restorers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL8000446A true NL8000446A (nl) | 1980-12-03 |
Family
ID=10996152
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL8000446A NL8000446A (nl) | 1979-06-01 | 1980-01-24 | Samenstellingen voor toepassing als cosmetica en werkwijze voor de bereiding van de werkzame bestand- delen daarvan. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4329338A (es) |
| JP (1) | JPS5618909A (es) |
| AU (1) | AU531858B2 (es) |
| BE (1) | BE881494A (es) |
| CA (1) | CA1150152A (es) |
| CH (1) | CH644263A5 (es) |
| DE (1) | DE3014045A1 (es) |
| DK (1) | DK20580A (es) |
| ES (1) | ES488087A0 (es) |
| FI (1) | FI800155A7 (es) |
| FR (1) | FR2457684A1 (es) |
| GB (2) | GB2049419B (es) |
| GR (1) | GR72738B (es) |
| HU (1) | HU184626B (es) |
| IL (1) | IL59100A (es) |
| IT (1) | IT1140529B (es) |
| LU (1) | LU82124A1 (es) |
| NL (1) | NL8000446A (es) |
| NO (1) | NO152773C (es) |
| NZ (1) | NZ192579A (es) |
| PT (1) | PT70721A (es) |
| SE (1) | SE8000131L (es) |
| YU (1) | YU11680A (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5037969A (en) * | 1986-07-03 | 1991-08-06 | Takeda Chemical Industries, Ltd. | Glycosyl derivatives and use thereof |
| LU86574A1 (fr) * | 1986-09-08 | 1988-04-05 | Oreal | Composition pour induire et stimuler la croissance des cheveux et freiner leur chute,a base d'esters nicotiniques et de derives de pyrimidine |
| US6465514B1 (en) | 1986-12-29 | 2002-10-15 | Kenneth M. Hallam | Methods and compositions for the promotion of hair growth |
| US6187815B1 (en) * | 1992-02-18 | 2001-02-13 | Kenneth M. Hallam | Methods and compositions for the promotion of hair growth |
| US5833998A (en) * | 1995-11-06 | 1998-11-10 | The Procter & Gamble Company | Topical compositions for regulating the oily/shiny appearance of skin |
| HUT78139A (hu) * | 1995-12-22 | 2000-11-28 | BIOREX Kutató és Fejlesztő Rt. | Készítmény, különösen a bőr öregedési folyamatainak mérséklésére |
| FR2751878B1 (fr) * | 1996-07-30 | 1998-09-04 | Oreal | Utilisation dans une composition d'un extrait d'au moins une labiee |
| US5954675A (en) * | 1997-07-07 | 1999-09-21 | Dellagatta; Enrico Michael | Method of ultrasonic therapy |
| EP1143954B1 (en) | 1998-12-01 | 2004-08-11 | University of Kentucky Research Foundation | Use of nicotinic acid derivatives for the treatment of dna damage in skin cells |
| DE10133196A1 (de) * | 2001-07-07 | 2003-01-23 | Beiersdorf Ag | Nicotinsäure enthaltende kosmetische und dermatologische Zubereitungen zur Behandlung und aktiven Prävention trockener Haut und anderer negativer Veränderungen der physiologischen Homöostase der gesunden Haut |
| US7736636B2 (en) * | 2003-02-12 | 2010-06-15 | Shaker Mousa | Method for treating occlusive vascular diseases & wound healing |
| US8354116B2 (en) * | 2007-06-18 | 2013-01-15 | Biochemics, Inc. | Bifunctional synthetic molecules |
| JP2009023923A (ja) * | 2007-07-18 | 2009-02-05 | Koyo Chemical Kk | 有機酸塩の製造方法、並びにその用途 |
| WO2016074966A1 (en) * | 2014-11-13 | 2016-05-19 | Unilever Plc | Method of improving hair volume |
| US11767314B2 (en) | 2018-11-02 | 2023-09-26 | Conopco, Inc. | Bioenergetic nicotinic acid glycerol esters, compositions and methods of using same |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE835038C (de) * | 1951-01-16 | 1952-03-27 | Nordmark Werke Gmbh | Haarpflegemittel |
| DE1216307B (de) * | 1958-10-30 | 1966-05-12 | Krewel Leuffen Ges Mit Beschra | Verfahren zur Herstellung von Nicotinsaeureestern mehrwertiger Alkohole |
| DE1617321A1 (de) * | 1965-05-13 | 1971-03-04 | Josef Brandstetter | Hautbehandlungspraeparat |
| GB1097664A (en) * | 1965-11-10 | 1968-01-03 | Kyoto Pharma Ind | 3-(o-methoxyphenoxy)-1,2-propanediol nicotinates |
| DE1695218A1 (de) * | 1967-12-28 | 1971-03-18 | Herbrand Kg Dr | Therapeutisch wirksame Nikotinsaeureester von Xylit,Adonit und Arabit |
| BE757590A (fr) * | 1969-10-16 | 1971-03-16 | Blendax Werke Schneider Co | Produits pour le traitement et l'hygiene de la cavite buccale |
| US3950324A (en) * | 1974-01-25 | 1976-04-13 | Hoffmann-La Roche Inc. | D-glucose-1-0-nicotinoyl-2-deoxy-2-nictinamido derivatives |
| ES438246A1 (es) * | 1975-06-04 | 1977-01-16 | Alter Sa | Un procedimiento de preparacion del glicol 2-(p-clorofenoci)-2-metilpropinato nicotinato. |
| CH599242A5 (es) * | 1975-09-12 | 1978-05-31 | Ciba Geigy Ag | |
| GB2002233A (en) * | 1977-08-02 | 1979-02-21 | Champion J | Topical compositions containing vasodilators |
| US4201235A (en) * | 1978-01-03 | 1980-05-06 | Mare Corporation | Amino acid-vitamin formulations for skin, hair and scalp conditioners |
-
1979
- 1979-06-01 HU HU79FE1046A patent/HU184626B/hu not_active IP Right Cessation
-
1980
- 1980-01-08 SE SE8000131A patent/SE8000131L/xx not_active Application Discontinuation
- 1980-01-08 NO NO800039A patent/NO152773C/no unknown
- 1980-01-09 IL IL59100A patent/IL59100A/xx unknown
- 1980-01-10 NZ NZ192579A patent/NZ192579A/xx unknown
- 1980-01-11 CA CA000343518A patent/CA1150152A/en not_active Expired
- 1980-01-14 AU AU54586/80A patent/AU531858B2/en not_active Ceased
- 1980-01-15 GR GR60964A patent/GR72738B/el unknown
- 1980-01-17 YU YU00116/80A patent/YU11680A/xx unknown
- 1980-01-17 DK DK20580A patent/DK20580A/da not_active Application Discontinuation
- 1980-01-18 FI FI800155A patent/FI800155A7/fi not_active Application Discontinuation
- 1980-01-18 GB GB8001794A patent/GB2049419B/en not_active Expired
- 1980-01-22 US US06/114,425 patent/US4329338A/en not_active Expired - Lifetime
- 1980-01-23 PT PT70721A patent/PT70721A/pt unknown
- 1980-01-24 NL NL8000446A patent/NL8000446A/nl not_active Application Discontinuation
- 1980-01-31 LU LU82124A patent/LU82124A1/fr unknown
- 1980-01-31 ES ES488087A patent/ES488087A0/es active Granted
- 1980-01-31 FR FR8002070A patent/FR2457684A1/fr not_active Withdrawn
- 1980-02-01 BE BE1/9707A patent/BE881494A/fr not_active IP Right Cessation
- 1980-02-05 IT IT19711/80A patent/IT1140529B/it active
- 1980-02-21 CH CH138980A patent/CH644263A5/de not_active IP Right Cessation
- 1980-04-11 DE DE19803014045 patent/DE3014045A1/de not_active Withdrawn
- 1980-05-09 JP JP6081580A patent/JPS5618909A/ja active Pending
-
1983
- 1983-04-15 GB GB838310267A patent/GB8310267D0/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NO152773C (no) | 1985-11-20 |
| HU184626B (en) | 1984-09-28 |
| GR72738B (es) | 1983-12-02 |
| CH644263A5 (de) | 1984-07-31 |
| NO800039L (no) | 1980-12-02 |
| GB2049419A (en) | 1980-12-31 |
| US4329338A (en) | 1982-05-11 |
| DK20580A (da) | 1980-12-02 |
| BE881494A (fr) | 1980-08-01 |
| FR2457684A1 (fr) | 1980-12-26 |
| AU5458680A (en) | 1980-12-04 |
| IT1140529B (it) | 1986-10-01 |
| FI800155A7 (fi) | 1981-01-01 |
| PT70721A (en) | 1980-02-01 |
| AU531858B2 (en) | 1983-09-08 |
| NZ192579A (en) | 1982-02-23 |
| IL59100A (en) | 1984-02-29 |
| GB8310267D0 (en) | 1983-05-18 |
| ES8101884A1 (es) | 1980-12-16 |
| ES488087A0 (es) | 1980-12-16 |
| LU82124A1 (fr) | 1980-04-23 |
| YU11680A (en) | 1983-06-30 |
| IL59100A0 (en) | 1980-05-30 |
| DE3014045A1 (de) | 1980-12-11 |
| CA1150152A (en) | 1983-07-19 |
| SE8000131L (sv) | 1980-12-02 |
| JPS5618909A (en) | 1981-02-23 |
| NO152773B (no) | 1985-08-12 |
| IT8019711A0 (it) | 1980-02-05 |
| GB2049419B (en) | 1984-03-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NL8000446A (nl) | Samenstellingen voor toepassing als cosmetica en werkwijze voor de bereiding van de werkzame bestand- delen daarvan. | |
| FR2764891A1 (fr) | Derive de l'acide l-ascorbique stable dans l'eau, procede pour sa preparation et composition cosmetique de blanchiment de la peau le contenant | |
| RS52389B (sr) | Heterociklična jedinjenja zasnovana na n6-supstituisanom adeninu, postupci izrade, njihova upotreba za izradu lekova, kozmetičkih preparata i regulatora rasta, farmaceutski preparati, kozmetički preparati i regulatori rasta koji sadrže ova jedinjenja | |
| EP2049075A2 (de) | Verwendung von ascorbinsäurederivaten zur funktionalisierung von matrices | |
| DE2655500A1 (de) | Glucosaminderivate und ein verfahren zu deren herstellung | |
| JPH10298174A (ja) | アスコルビン酸誘導体及びそれを含有するビタミンｃ剤 | |
| FR2813191A1 (fr) | Derives du tocopherol et procede de preparation de ceux-ci | |
| FR2783517A1 (fr) | Nouveaux derives de l'acide 10-hyroxy-2-decenoique et utilisation dans une composition destinee a favoriser la desquamation de la peau, et composition le comprenant | |
| JPH06256274A (ja) | 新規なアシルアミノ酸 | |
| EP0142732A2 (en) | Pheophorbide derivatives and pharmaceutical preparations containing them | |
| EP0968221B1 (fr) | Nouveaux derives de l'acide salicylique et leur utilisation dans les compositions cosmetiques ou dermatologiques | |
| FR2590897A1 (fr) | Nouveaux derives de 6 amino 1,2-dihydro-1-hydroxy-2-imino-pyrimidine, leur procede de preparation et compositions cosmetiques les renfermant | |
| Wolfrom et al. | The Reactivity of the Monothioacetals of Glucose and Galactose in Relation to Furanoside Synthesis1 | |
| JP2004523526A (ja) | 炭水化物脂肪酸エステルの製造方法 | |
| EP0017705B1 (de) | Phenylalanyltryptophan-Derivate, sie enthaltende Arzneimittel, ihre Herstellung und Verwendung | |
| EP2238121A1 (de) | Uva filter auf der basis von ascorbinsäurederivaten | |
| US3578655A (en) | Carbohydrate agent of high water retention power,process of making same,and composition containing same | |
| US3751564A (en) | Process for preparing scleroprotein-alkyl thiosulfate agents for the care of the hair | |
| WO1994005681A1 (de) | Neue acetale von ketophosphamid und alkylglycosiden | |
| WO2009097953A1 (de) | Uvb filter auf der basis von ascorbinsäurederivaten | |
| US3376334A (en) | Carbonic acid esters of pantothenic acid | |
| JP7682451B2 (ja) | 新規化合物、ｎｏ産生抑制剤、抗炎症剤および化合物の製造方法 | |
| SU143381A1 (ru) | Способ получени сложных эфиров сахарозы | |
| FR2465722A1 (fr) | 3-(hydroxy ou hydroxymethyl)-5-(4-pyridinyl)-2(1h)-pyridinones, leur preparation et leur utilisation comme agents cardiotoniques | |
| KR830002843B1 (ko) | 알킬-케토헥소 피라노사이드 유도체의 제조방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A85 | Still pending on 85-01-01 | ||
| BV | The patent application has lapsed |