NL7714066A - 1,4-DIHYDROPYRIDINE COMPOUNDS, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS. - Google Patents
1,4-DIHYDROPYRIDINE COMPOUNDS, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS.Info
- Publication number
- NL7714066A NL7714066A NL7714066A NL7714066A NL7714066A NL 7714066 A NL7714066 A NL 7714066A NL 7714066 A NL7714066 A NL 7714066A NL 7714066 A NL7714066 A NL 7714066A NL 7714066 A NL7714066 A NL 7714066A
- Authority
- NL
- Netherlands
- Prior art keywords
- compounds
- preparation
- pharmaceutical preparations
- preparations containing
- dihydropyridine
- Prior art date
Links
- YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical class C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB52720/76A GB1591089A (en) | 1976-12-17 | 1976-12-17 | 1,4-dihydropyridine derivatives and process for preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL7714066A true NL7714066A (en) | 1978-06-20 |
Family
ID=10465031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL7714066A NL7714066A (en) | 1976-12-17 | 1977-12-19 | 1,4-DIHYDROPYRIDINE COMPOUNDS, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS. |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS5948828B2 (en) |
| AR (2) | AR221478A1 (en) |
| AT (1) | AT367401B (en) |
| AU (1) | AU518206B2 (en) |
| BE (1) | BE861964A (en) |
| CH (1) | CH633266A5 (en) |
| DE (1) | DE2756226A1 (en) |
| DK (2) | DK563377A (en) |
| ES (3) | ES465137A1 (en) |
| FR (1) | FR2374307A1 (en) |
| GB (1) | GB1591089A (en) |
| HU (1) | HU176454B (en) |
| NL (1) | NL7714066A (en) |
| SE (2) | SE7714374L (en) |
| ZA (1) | ZA777532B (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4307103A (en) * | 1978-09-08 | 1981-12-22 | Fujisawa Pharmaceutical Co., Ltd. | Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same |
| CA1117117A (en) * | 1978-10-10 | 1982-01-26 | Fujisawa Pharmaceutical Co., Ltd. | 2-methyl-dihydropyridine compound, processes for preparation thereof and pharmaceutical composition comprising the same |
| DE2935451A1 (en) * | 1979-09-01 | 1981-03-19 | Bayer Ag, 5090 Leverkusen | OPTICALLY ACTIVE 1,4-DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT |
| DE3018259A1 (en) * | 1980-05-13 | 1981-11-19 | Bayer Ag, 5090 Leverkusen | 1,4-DIHYDROPYRIDINE WITH DIFFERENT SUBSTITUENTS IN 2- AND 6-POSITIONS, METHODS FOR THEIR PRODUCTION AND THEIR USE IN MEDICINAL PRODUCTS |
| JPS57175164A (en) * | 1981-04-18 | 1982-10-28 | Banyu Pharmaceut Co Ltd | 1,4-dihydropyridine derivative and its preparation |
| EP0080220B1 (en) * | 1981-11-17 | 1986-02-19 | FISONS plc | Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals |
| ZA83959B (en) * | 1982-03-10 | 1984-09-26 | Sandoz Ltd | 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them |
| HU197881B (en) * | 1982-08-06 | 1989-06-28 | Banyu Pharma Co Ltd | Process for producing new carbamoyl-oxy-alkyl-carboxy-lic acid derivatives |
| GB8412208D0 (en) * | 1984-05-12 | 1984-06-20 | Pfizer Ltd | Quinolone inotropic agents |
| US4678796A (en) * | 1984-11-30 | 1987-07-07 | Warner-Lambert Company | 2-alkylidene derivatives of 1,2,3,4-tetrahydropyridine-2,5-pyridine carboxylic acid dialkyl esters useful for treatment of cardiovascular disorders |
| CA1267416A (en) | 1985-06-17 | 1990-04-03 | Ila Sircar | 1,4-dihydropyridine derivatives useful for the treatment of cardiovascular disorders |
| EP0226271B1 (en) * | 1985-08-21 | 1990-11-22 | GLAXO S.p.A. | 1,4-dihydropyridine compounds and their preparation and pharmaceutical formulation |
| DE3544211A1 (en) * | 1985-12-13 | 1987-06-19 | Bayer Ag | NEW, FLUORINE 1,4-DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS |
| IT1204460B (en) * | 1986-02-20 | 1989-03-01 | Glaxo Spa | HETEROCYCLIC DERIVATIVES |
| FR2596760B1 (en) * | 1986-04-02 | 1988-12-09 | Sori Soc Rech Ind | DISSYMMETRIC DERIVATIVES OF 1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID, METHODS OF PREPARATION AND THERAPEUTIC USE |
| US4732898A (en) * | 1986-04-29 | 1988-03-22 | Warner-Lambert Company | 2-(2-aryl-2-oxoalkylidene) analogs of-3,5-pyridinedicarboxylic acid dialkyl esters useful for treatment of cardiovascular disorders |
| JPS63115890A (en) * | 1986-10-31 | 1988-05-20 | Nippon Shinyaku Co Ltd | 2-substituted 1,4-dihydropyridine derivative |
| US5977369A (en) * | 1995-12-28 | 1999-11-02 | Napp Technologies, Inc. | Process to prepare dihydropyridine and derivatives thereof |
| CN103951608B (en) * | 2009-08-04 | 2016-04-27 | 喜德生(苏州)医药科技有限公司 | Nilvadipine crystal formation and preparation method thereof |
| CN103254122B (en) * | 2013-06-19 | 2015-04-22 | 湖南师范大学 | Preparation method of cardiovascular drug nilvadipine |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1963188A1 (en) * | 1969-12-17 | 1971-06-24 | Bayer Ag | New cyanophenyl-1,4-dihydropyridine derivatives |
| DE2248150A1 (en) * | 1972-09-30 | 1974-04-04 | Bayer Ag | DIHYDROPYRIDINE POLYESTER, METHOD FOR MANUFACTURING AND USING THEM AS A MEDICINAL PRODUCT |
| US3946027A (en) * | 1972-09-30 | 1976-03-23 | Bayer Aktiengesellschaft | 3,5,6-Tricarboxy-4-pyridyl-1,4-dihydropyridine derivatives |
| US3946028A (en) * | 1972-09-30 | 1976-03-23 | Bayer Aktiengesellschaft | 2,3,5,6-Tetracarboxy-4-pyridyl-1,4-dihydropyridine derivatives |
| DE2335466A1 (en) * | 1973-07-12 | 1975-01-30 | Bayer Ag | ALCOXY ALKYL-1,4-DIHYDROPYRIDINE, THE METHOD FOR THEIR MANUFACTURING AND THEIR USE AS A MEDICINAL PRODUCT |
| CH607848A5 (en) * | 1974-06-04 | 1978-11-30 | Bayer Ag | |
| GB1552911A (en) * | 1975-07-02 | 1979-09-19 | Fujisawa Pharmaceutical Co | 1,4 dihydropyridine derivatives and the preparation thereof |
-
1976
- 1976-12-17 GB GB52720/76A patent/GB1591089A/en not_active Expired
-
1977
- 1977-12-16 AT AT0901877A patent/AT367401B/en not_active IP Right Cessation
- 1977-12-16 CH CH1553477A patent/CH633266A5/en not_active IP Right Cessation
- 1977-12-16 FR FR7738126A patent/FR2374307A1/en active Granted
- 1977-12-16 SE SE7714374A patent/SE7714374L/en not_active Application Discontinuation
- 1977-12-16 AR AR270392A patent/AR221478A1/en active
- 1977-12-16 JP JP52152290A patent/JPS5948828B2/en not_active Expired
- 1977-12-16 DE DE19772756226 patent/DE2756226A1/en not_active Ceased
- 1977-12-16 AU AU31657/77A patent/AU518206B2/en not_active Expired
- 1977-12-16 HU HU77FU358A patent/HU176454B/en unknown
- 1977-12-16 BE BE183553A patent/BE861964A/en not_active IP Right Cessation
- 1977-12-16 ES ES465137A patent/ES465137A1/en not_active Expired
- 1977-12-16 DK DK563377A patent/DK563377A/en not_active Application Discontinuation
- 1977-12-19 ZA ZA00777532A patent/ZA777532B/en unknown
- 1977-12-19 NL NL7714066A patent/NL7714066A/en not_active Application Discontinuation
-
1978
- 1978-10-16 ES ES474233A patent/ES474233A1/en not_active Expired
- 1978-10-16 ES ES474234A patent/ES474234A1/en not_active Expired
-
1979
- 1979-07-13 AR AR277301A patent/AR221887A1/en active
-
1982
- 1982-04-16 DK DK172182A patent/DK172182A/en active IP Right Grant
- 1982-07-13 SE SE8204312A patent/SE8204312D0/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2374307A1 (en) | 1978-07-13 |
| SE8204312L (en) | 1982-07-13 |
| AR221478A1 (en) | 1981-02-13 |
| CH633266A5 (en) | 1982-11-30 |
| ES474234A1 (en) | 1979-04-01 |
| AU518206B2 (en) | 1981-09-17 |
| ES465137A1 (en) | 1979-01-01 |
| ES474233A1 (en) | 1979-11-01 |
| ZA777532B (en) | 1978-10-25 |
| AR221887A1 (en) | 1981-03-31 |
| GB1591089A (en) | 1981-06-10 |
| ATA901877A (en) | 1981-11-15 |
| SE7714374L (en) | 1978-06-18 |
| JPS5395977A (en) | 1978-08-22 |
| AU3165777A (en) | 1979-06-21 |
| DE2756226A1 (en) | 1978-06-29 |
| AT367401B (en) | 1982-07-12 |
| BE861964A (en) | 1978-06-16 |
| FR2374307B1 (en) | 1981-02-13 |
| DK172182A (en) | 1982-04-16 |
| SE8204312D0 (en) | 1982-07-13 |
| JPS5948828B2 (en) | 1984-11-29 |
| DK563377A (en) | 1978-06-18 |
| HU176454B (en) | 1981-03-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BV | The patent application has lapsed |