NL7610038A - Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitatively - Google Patents
Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitativelyInfo
- Publication number
- NL7610038A NL7610038A NL7610038A NL7610038A NL7610038A NL 7610038 A NL7610038 A NL 7610038A NL 7610038 A NL7610038 A NL 7610038A NL 7610038 A NL7610038 A NL 7610038A NL 7610038 A NL7610038 A NL 7610038A
- Authority
- NL
- Netherlands
- Prior art keywords
- capsule
- same
- therapeutically active
- active substances
- multichambered
- Prior art date
Links
- 239000002775 capsule Substances 0.000 title abstract 5
- 239000013543 active substance Substances 0.000 title abstract 2
- 239000000463 material Substances 0.000 abstract 5
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 239000001828 Gelatine Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 210000000936 intestine Anatomy 0.000 abstract 1
- 238000005192 partition Methods 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A capsule for therapeutically active substances has a wall which is of a material soluble in the stomach or intestine, e.g. gelatine. The capsule is closed by a cover and forms a holder for the therapeutical material; the interior being divided by >=1 partition into >=2 or more compartments. The separate compartments may contain similarly active therapeutical substances or alternatively, the medicaments contained may differ in their effect. The solubility of the materials of the outer capsule and of the covers is different. Alternatively the speed at which the material dissolve may be the same. The contents of the separate compartments may be the same in quantity or they may be different. The capsule allows the same or differing materials to be released into the alimentary duct, at different intervals of time in the same or in widely differing quantities.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL7610038A NL7610038A (en) | 1976-09-09 | 1976-09-09 | Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitatively |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL7610038A NL7610038A (en) | 1976-09-09 | 1976-09-09 | Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitatively |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL7610038A true NL7610038A (en) | 1978-03-13 |
Family
ID=19826865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL7610038A NL7610038A (en) | 1976-09-09 | 1976-09-09 | Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitatively |
Country Status (1)
| Country | Link |
|---|---|
| NL (1) | NL7610038A (en) |
Cited By (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0308637A1 (en) * | 1987-08-21 | 1989-03-29 | Dieter Dr. Stephan | Capsules for the pharmaceutically active contents of a medicament |
| US5074426A (en) * | 1986-11-13 | 1991-12-24 | Warner-Lambert Company | Dividable capsule |
| US5310555A (en) * | 1992-07-24 | 1994-05-10 | Midwestern Bio-Ag Products And Services, Inc. | Oral nutritional and dietary composition |
| US5501857A (en) * | 1992-07-24 | 1996-03-26 | Midwestern Bio-Ag Products & Services, Inc. | Oral nutritional and dietary composition |
| EP0804174A4 (en) * | 1993-07-21 | 1998-09-09 | Univ Kentucky Res Found | A multicompartment hard capsule with control release properties |
| WO2002007710A3 (en) * | 2000-07-20 | 2002-04-25 | Mw Encap Ltd | Delivery device |
| GB2370554A (en) * | 1999-11-17 | 2002-07-03 | Reckitt Benckiser | Rigid water-soluble containers |
| WO2002060385A2 (en) | 2001-01-30 | 2002-08-08 | Smithkline Beecham Plc. | Pharmaceutical formulation |
| WO2004010978A1 (en) | 2002-07-25 | 2004-02-05 | Glaxo Group Limited | Multicomponent pharmaceutical dosage form |
| WO2005009380A2 (en) | 2003-07-21 | 2005-02-03 | Smith Kline Beecham P.L.C. | Pharmaceutical formulations |
| WO2006055886A2 (en) | 2004-11-19 | 2006-05-26 | Smithkline Beecham Corporation | Method for customized dispensing of variable dose drug combination products for individualizing of therapies |
| EP1248595A4 (en) * | 2000-01-20 | 2006-06-14 | Delsys Pharmaceutical Corp | Multi-step drug dosage forms |
| WO2009050190A2 (en) | 2007-10-15 | 2009-04-23 | Glaxo Group Limited | Linkers for multipart dosage forms for release of one or more pharmaceutical compositions, and the resulting dosage forms |
| WO2009087483A2 (en) | 2007-11-08 | 2009-07-16 | Glaxo Group Limited | Pharmaceutical formulations |
| US7842308B2 (en) | 2001-01-30 | 2010-11-30 | Smithkline Beecham Limited | Pharmaceutical formulation |
| US7883721B2 (en) | 2001-01-30 | 2011-02-08 | Smithkline Beecham Limited | Pharmaceutical formulation |
| US8147871B2 (en) | 2004-03-12 | 2012-04-03 | Capsugel Belgium Bvba | Pharmaceutical formulations |
| US8293159B2 (en) | 2007-10-15 | 2012-10-23 | Capsugel Belgium | Method and apparatus for manufacturing filled linkers |
| WO2013050973A1 (en) * | 2011-10-06 | 2013-04-11 | Market Demand Trading 767 Proprietary Limited | A method and apparatus for manufacturing a capsule |
| US8440224B2 (en) | 1999-07-30 | 2013-05-14 | Capsugel Belgium Nv | Multi-component pharmaceutical dosage form |
| US8454992B2 (en) | 2007-10-15 | 2013-06-04 | Capsugel Belgium Nv | Paneled capsule shells for release of pharmaceutical compositions |
| WO2014162288A1 (en) | 2013-04-03 | 2014-10-09 | Binutra Incorporated | Capsule with internal diaphragm |
| EP3028694A1 (en) * | 2014-12-02 | 2016-06-08 | Capsugel Belgium NV | Dosage form articles for delayed release |
| WO2017062956A1 (en) * | 2015-10-09 | 2017-04-13 | Binutra Incorporated | Capsule with internal diaphragm and solid ingredients |
| US10653622B1 (en) | 2015-04-13 | 2020-05-19 | Pharmacoustics Technologies LLC | Individualized solid dosage products and a system and method for the globally integrated pharmaceutical manufacturing and its monitoring thereof |
-
1976
- 1976-09-09 NL NL7610038A patent/NL7610038A/en not_active Application Discontinuation
Cited By (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5074426A (en) * | 1986-11-13 | 1991-12-24 | Warner-Lambert Company | Dividable capsule |
| EP0308637A1 (en) * | 1987-08-21 | 1989-03-29 | Dieter Dr. Stephan | Capsules for the pharmaceutically active contents of a medicament |
| US5310555A (en) * | 1992-07-24 | 1994-05-10 | Midwestern Bio-Ag Products And Services, Inc. | Oral nutritional and dietary composition |
| US5501857A (en) * | 1992-07-24 | 1996-03-26 | Midwestern Bio-Ag Products & Services, Inc. | Oral nutritional and dietary composition |
| EP0804174A4 (en) * | 1993-07-21 | 1998-09-09 | Univ Kentucky Res Found | A multicompartment hard capsule with control release properties |
| US8440224B2 (en) | 1999-07-30 | 2013-05-14 | Capsugel Belgium Nv | Multi-component pharmaceutical dosage form |
| GB2370554A (en) * | 1999-11-17 | 2002-07-03 | Reckitt Benckiser | Rigid water-soluble containers |
| GB2370554B (en) * | 1999-11-17 | 2002-11-20 | Reckitt Benckiser | Rigid water-soluble containers |
| EP1248595A4 (en) * | 2000-01-20 | 2006-06-14 | Delsys Pharmaceutical Corp | Multi-step drug dosage forms |
| WO2002007710A3 (en) * | 2000-07-20 | 2002-04-25 | Mw Encap Ltd | Delivery device |
| US8367101B2 (en) | 2001-01-30 | 2013-02-05 | Capsugel Belgium Nv | Pharmaceutical formulation |
| WO2002060384A2 (en) | 2001-01-30 | 2002-08-08 | Smithkline Beecham Plc. | Pharmaceutical formulation |
| US8361498B2 (en) | 2001-01-30 | 2013-01-29 | Capsugel Belgium Nv | Pharmaceutical formulation |
| US7842308B2 (en) | 2001-01-30 | 2010-11-30 | Smithkline Beecham Limited | Pharmaceutical formulation |
| US7883721B2 (en) | 2001-01-30 | 2011-02-08 | Smithkline Beecham Limited | Pharmaceutical formulation |
| EP2366384A2 (en) | 2001-01-30 | 2011-09-21 | Pfizer Inc. | Pharmaceutical formulation |
| EP2366382A2 (en) | 2001-01-30 | 2011-09-21 | Pfizer Inc. | Pharmaceutical formulation |
| EP2366383A2 (en) | 2001-01-30 | 2011-09-21 | Pfizer Inc. | Pharmaceutical formulation |
| WO2002060385A2 (en) | 2001-01-30 | 2002-08-08 | Smithkline Beecham Plc. | Pharmaceutical formulation |
| WO2004010978A1 (en) | 2002-07-25 | 2004-02-05 | Glaxo Group Limited | Multicomponent pharmaceutical dosage form |
| EP2556825A1 (en) | 2002-07-25 | 2013-02-13 | Capsugel Belgium NV | Multicomponent pharmaceutical dosage form |
| WO2005009380A2 (en) | 2003-07-21 | 2005-02-03 | Smith Kline Beecham P.L.C. | Pharmaceutical formulations |
| US8147871B2 (en) | 2004-03-12 | 2012-04-03 | Capsugel Belgium Bvba | Pharmaceutical formulations |
| WO2006055886A2 (en) | 2004-11-19 | 2006-05-26 | Smithkline Beecham Corporation | Method for customized dispensing of variable dose drug combination products for individualizing of therapies |
| EP2537506A1 (en) | 2007-10-15 | 2012-12-26 | Capsugel Belgium NV | Linkers for multipart dosage forms for release of one or more parmaceutical compositions, and the resulting dosage forms |
| US8293159B2 (en) | 2007-10-15 | 2012-10-23 | Capsugel Belgium | Method and apparatus for manufacturing filled linkers |
| WO2009050190A2 (en) | 2007-10-15 | 2009-04-23 | Glaxo Group Limited | Linkers for multipart dosage forms for release of one or more pharmaceutical compositions, and the resulting dosage forms |
| US8454992B2 (en) | 2007-10-15 | 2013-06-04 | Capsugel Belgium Nv | Paneled capsule shells for release of pharmaceutical compositions |
| WO2009087483A2 (en) | 2007-11-08 | 2009-07-16 | Glaxo Group Limited | Pharmaceutical formulations |
| JP2014528319A (en) * | 2011-10-06 | 2014-10-27 | バイオ カプセル ファーマシューティカル アンド ニュートリショナルプロダクツ プロプライアタリー リミティド | Method and apparatus for manufacturing capsules |
| EP3069707A1 (en) * | 2011-10-06 | 2016-09-21 | Binutra Incorporated | A method and apparatus for manufacturing a capsule |
| CN103987357A (en) * | 2011-10-06 | 2014-08-13 | 生物胶囊药物和营养产品私人有限公司 | Capsule manufacturing method and device |
| CN103987357B (en) * | 2011-10-06 | 2017-12-12 | 康宝卡普股份有限公司 | Capsule manufacturing method and device |
| WO2013050973A1 (en) * | 2011-10-06 | 2013-04-11 | Market Demand Trading 767 Proprietary Limited | A method and apparatus for manufacturing a capsule |
| JP2014528318A (en) * | 2011-10-06 | 2014-10-27 | バイオ カプセル ファーマシューティカル アンド ニュートリショナルプロダクツ プロプライアタリー リミティド | Method and apparatus for manufacturing capsules |
| US9340004B2 (en) | 2011-10-06 | 2016-05-17 | Bio Capsule Pharmaceutical And Nutritional Products (Pty) Ltd. | Method and apparatus for manufacturing a capsule |
| RU2622749C9 (en) * | 2011-10-06 | 2017-08-30 | Байо Кэпсьюл Фармасьютикал Энд Ньютришнал Продактс Проприетери Лимитед | Method and device for manufacturing capsules |
| US12043018B2 (en) * | 2011-10-06 | 2024-07-23 | Combocap, Inc. | Method and apparatus for manufacturing a capsule |
| WO2013050974A1 (en) * | 2011-10-06 | 2013-04-11 | Market Demand Trading 767 Proprietary Limited | A method and apparatus for manufacturing a capsule |
| RU2622749C2 (en) * | 2011-10-06 | 2017-06-19 | Байо Кэпсьюл Фармасьютикал Энд Ньютришнал Продактс Проприетери Лимитед | Method and device for manufacturing capsules |
| US10046549B2 (en) | 2011-10-06 | 2018-08-14 | Combocap, Inc. | Method and apparatus for manufacturing a capsule |
| EP3069708A1 (en) * | 2011-10-06 | 2016-09-21 | Binutra Incorporated | Capsule |
| RU2622748C2 (en) * | 2011-10-06 | 2017-06-19 | Байо Кэпсьюл Фармасьютикал Энд Ньютришнал Продактс Проприетери Лимитед | Method and device for manufacturing capsules |
| AU2012320100B2 (en) * | 2011-10-06 | 2017-01-19 | Combocap, Inc. | A method and apparatus for manufacturing a capsule |
| AU2012320099B2 (en) * | 2011-10-06 | 2017-02-02 | Combocap, Inc. | A method and apparatus for manufacturing a capsule |
| CN104010617B (en) * | 2011-10-06 | 2017-05-10 | 生物胶囊药物和营养产品私人有限公司 | A method and apparatus for manufacturing a capsule |
| CN105705142B (en) * | 2013-04-03 | 2020-07-10 | 康宝卡普股份有限公司 | Capsule with internal diaphragm |
| US9456987B2 (en) | 2013-04-03 | 2016-10-04 | Binutra, Inc. | Capsule with internal diaphragm |
| CN105705142A (en) * | 2013-04-03 | 2016-06-22 | 比纳特拉股份有限公司 | Capsule with internal diaphragm |
| JP2016515607A (en) * | 2013-04-03 | 2016-05-30 | ビヌトラ インコーポレイテッド | Capsule with internal partition |
| WO2014162288A1 (en) | 2013-04-03 | 2014-10-09 | Binutra Incorporated | Capsule with internal diaphragm |
| AU2014246703B2 (en) * | 2013-04-03 | 2018-07-19 | Combocap, Inc. | Capsule with internal diaphragm |
| WO2016087263A1 (en) * | 2014-12-02 | 2016-06-09 | Capsugel Belgium N.V. | Dosage form articles for delayed release |
| US10555908B2 (en) | 2014-12-02 | 2020-02-11 | Capsugel Belgium Nv | Dosage form articles for delayed release |
| EP3028694A1 (en) * | 2014-12-02 | 2016-06-08 | Capsugel Belgium NV | Dosage form articles for delayed release |
| US10653622B1 (en) | 2015-04-13 | 2020-05-19 | Pharmacoustics Technologies LLC | Individualized solid dosage products and a system and method for the globally integrated pharmaceutical manufacturing and its monitoring thereof |
| US12128135B2 (en) | 2015-04-13 | 2024-10-29 | Pharmacoustics Technologies LLC | Individualized solid dosage products and a system and method for the globally integrated pharmaceutical manufacturing and its monitoring thereof |
| CN108366959A (en) * | 2015-10-09 | 2018-08-03 | 科姆博盖股份有限公司 | Capsule with the whole internal spacer of volume-tunable |
| EP3359130A4 (en) * | 2015-10-09 | 2019-05-01 | Combocap, Inc. | DIAPHRAGM CAPSULE WITH ADJUSTABLE VOLUME |
| EP3359131A4 (en) * | 2015-10-09 | 2019-05-01 | Combocap, Inc. | INTERNAL DIAPHRAGM CAPSULE FOR ENHANCED BIOAVAILABILITY |
| WO2017062956A1 (en) * | 2015-10-09 | 2017-04-13 | Binutra Incorporated | Capsule with internal diaphragm and solid ingredients |
| US11160759B1 (en) | 2015-10-09 | 2021-11-02 | Combocap, Inc. | Capsule with internal diaphragm for improved bioavailability |
| US20220160641A1 (en) * | 2015-10-09 | 2022-05-26 | Combocap, Inc. | Capsule with internal diaphragm for improved bioavailability |
| US11357732B2 (en) | 2015-10-09 | 2022-06-14 | Combocap, Inc. | Capsule with volume-adjustable internal diaphragm |
| US11478429B2 (en) | 2015-10-09 | 2022-10-25 | Combocap, Inc. | Capsule with internal diaphragm and solid ingredients |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BV | The patent application has lapsed |