NL7017830A - Substd. 1-phenoxy 2-hydroxy-3-alkyl aminopropanes - beta-adrenolytics, antiarrhythmics and hypotensives substd. 1-phenoxy 2-hydroxy-3-alkyl aminopropanes - beta-adrenolytics, anti-arrhythmics and hypotensives substitute phenoxy hydroxy alkyl aminopropan - Google Patents
Substd. 1-phenoxy 2-hydroxy-3-alkyl aminopropanes - beta-adrenolytics, antiarrhythmics and hypotensives substd. 1-phenoxy 2-hydroxy-3-alkyl aminopropanes - beta-adrenolytics, anti-arrhythmics and hypotensives substitute phenoxy hydroxy alkyl aminopropanInfo
- Publication number
- NL7017830A NL7017830A NL7017830A NL7017830A NL7017830A NL 7017830 A NL7017830 A NL 7017830A NL 7017830 A NL7017830 A NL 7017830A NL 7017830 A NL7017830 A NL 7017830A NL 7017830 A NL7017830 A NL 7017830A
- Authority
- NL
- Netherlands
- Prior art keywords
- alkyl
- phenoxy
- hydroxy
- adrenolytics
- hypotensives
- Prior art date
Links
- 208000001953 Hypotension Diseases 0.000 title abstract 3
- 230000003288 anthiarrhythmic effect Effects 0.000 title abstract 3
- 239000003416 antiarrhythmic agent Substances 0.000 title abstract 3
- 208000021822 hypotensive Diseases 0.000 title abstract 3
- 230000002959 anti-hypotensive effect Effects 0.000 title abstract 2
- 230000001077 hypotensive effect Effects 0.000 title 1
- -1 phenoxy hydroxy Chemical group 0.000 title 1
- WGYKZJWCGVVSQN-UHFFFAOYSA-N propylamine Chemical compound CCCN WGYKZJWCGVVSQN-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Cpds. of general formula (I) R = Pri or But R' = (CH2)xCN, (CH2)XNH2, (CH2)x+1OH or CO2R4 where x = 1-3 and R4 = H or (1-4C)alkyl R2 = (1-4C)O- or S-alkyl, (2-4C)alkenyl, (2-4C)alkynyl, CN, or H (if R' is not = a cyano or amino gp.) R3 = H, halogen, (1-4C)alkyl or (1-4C)Alkyl. beta-Adrenolytics, anti-arrhythmics, and hypotensives.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL7017830A NL7017830A (en) | 1963-08-26 | 1970-12-07 | Substd. 1-phenoxy 2-hydroxy-3-alkyl aminopropanes - beta-adrenolytics, antiarrhythmics and hypotensives substd. 1-phenoxy 2-hydroxy-3-alkyl aminopropanes - beta-adrenolytics, anti-arrhythmics and hypotensives substitute phenoxy hydroxy alkyl aminopropan |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1963B0073262 DE1493454C3 (en) | 1963-08-26 | 1963-08-26 | 1 -Aryloxy ^ -hydroxy-S-isopropylaminopropane and their salts, as well as their production and pharmaceuticals based thereon |
| NL7017830A NL7017830A (en) | 1963-08-26 | 1970-12-07 | Substd. 1-phenoxy 2-hydroxy-3-alkyl aminopropanes - beta-adrenolytics, antiarrhythmics and hypotensives substd. 1-phenoxy 2-hydroxy-3-alkyl aminopropanes - beta-adrenolytics, anti-arrhythmics and hypotensives substitute phenoxy hydroxy alkyl aminopropan |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL7017830A true NL7017830A (en) | 1971-03-25 |
Family
ID=6977785
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL6409883A NL142950B (en) | 1963-08-26 | 1964-08-26 | PROCESS FOR THE PREPARATION OF AN 1-ARYLOXY-2-HYDROXY-3-ISOPROPYLAMINOPROPANE DERIVATIVE AND SALTS THEREOF, AND FOR THE PREPARATION OF (BETA) -ADRENOLYTICALLY ACTIVE PHARMACEUTICAL PREPARATIONS CONTAINING THESE PREPARATIONS. |
| NL7017830A NL7017830A (en) | 1963-08-26 | 1970-12-07 | Substd. 1-phenoxy 2-hydroxy-3-alkyl aminopropanes - beta-adrenolytics, antiarrhythmics and hypotensives substd. 1-phenoxy 2-hydroxy-3-alkyl aminopropanes - beta-adrenolytics, anti-arrhythmics and hypotensives substitute phenoxy hydroxy alkyl aminopropan |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL6409883A NL142950B (en) | 1963-08-26 | 1964-08-26 | PROCESS FOR THE PREPARATION OF AN 1-ARYLOXY-2-HYDROXY-3-ISOPROPYLAMINOPROPANE DERIVATIVE AND SALTS THEREOF, AND FOR THE PREPARATION OF (BETA) -ADRENOLYTICALLY ACTIVE PHARMACEUTICAL PREPARATIONS CONTAINING THESE PREPARATIONS. |
Country Status (13)
| Country | Link |
|---|---|
| JP (5) | JPS509780B1 (en) |
| BE (1) | BE652336A (en) |
| BR (1) | BR6462130D0 (en) |
| CH (6) | CH539606A (en) |
| CY (1) | CY572A (en) |
| DE (1) | DE1493454C3 (en) |
| DK (4) | DK129411B (en) |
| FI (2) | FI43881C (en) |
| FR (2) | FR1555463A (en) |
| GB (1) | GB1084793A (en) |
| IL (1) | IL21978A (en) |
| NL (2) | NL142950B (en) |
| SE (6) | SE318891B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE881436C (en) * | 1938-12-04 | 1953-06-29 | Ind G M B H | Device for removing the dust thrown off by bag filters |
| US3466325A (en) * | 1965-04-30 | 1969-09-09 | Haessle Ab | 1-(ortho-alkenyl phenoxy) - 2-hydroxy-3-isopropylaminopropanes and the salts thereof |
| US3541130A (en) * | 1967-02-06 | 1970-11-17 | Boehringer Sohn Ingelheim | 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes |
| US3868460A (en) * | 1967-02-06 | 1975-02-25 | Boehringer Sohn Ingelheim | Therapeutic compositions and method |
| GB1501632A (en) * | 1974-06-28 | 1978-02-22 | Cm Ind | Aromatic ketones having cardiovascular activity |
| JPS5418240U (en) * | 1977-07-07 | 1979-02-06 | ||
| JPS54133863U (en) * | 1978-03-08 | 1979-09-17 | ||
| DE2839475A1 (en) * | 1978-09-11 | 1980-03-20 | Dolorgiet Arzneimittelfabrik | ISOPROPYLAMINE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THE SAME |
-
1963
- 1963-08-26 DE DE1963B0073262 patent/DE1493454C3/en not_active Expired
-
1964
- 1964-08-25 CH CH1109264A patent/CH539606A/en not_active IP Right Cessation
- 1964-08-25 CH CH765173A patent/CH539608A/en not_active IP Right Cessation
- 1964-08-25 CH CH765073A patent/CH539607A/en not_active IP Right Cessation
- 1964-08-25 CH CH764973A patent/CH540225A/en not_active IP Right Cessation
- 1964-08-25 CH CH765273A patent/CH539609A/en not_active IP Right Cessation
- 1964-08-25 CH CH765373A patent/CH539610A/en not_active IP Right Cessation
- 1964-08-26 BE BE652336A patent/BE652336A/xx unknown
- 1964-08-26 FR FR1555463D patent/FR1555463A/fr not_active Expired
- 1964-08-26 IL IL2197864A patent/IL21978A/en unknown
- 1964-08-26 FI FI182164A patent/FI43881C/en active
- 1964-08-26 NL NL6409883A patent/NL142950B/en not_active IP Right Cessation
- 1964-08-26 FR FR986265A patent/FR3647M/en not_active Expired
- 1964-08-26 BR BR16213064A patent/BR6462130D0/en unknown
- 1964-08-26 JP JP4838064A patent/JPS509780B1/ja active Pending
- 1964-08-26 SE SE10240/64A patent/SE318891B/xx unknown
- 1964-08-26 SE SE129268A patent/SE346775B/xx unknown
- 1964-08-26 DK DK421664A patent/DK129411B/en unknown
- 1964-08-26 GB GB3495264A patent/GB1084793A/en not_active Expired
-
1967
- 1967-03-31 DK DK185167A patent/DK112739B/en unknown
- 1967-07-07 JP JP4341367A patent/JPS509782B1/ja active Pending
- 1967-07-07 JP JP4341467A patent/JPS5021454B1/ja active Pending
- 1967-07-07 JP JP4341167A patent/JPS509781B1/ja active Pending
- 1967-07-07 JP JP4341567A patent/JPS507047B1/ja active Pending
-
1968
- 1968-01-31 SE SE01294/68A patent/SE346778B/xx unknown
- 1968-01-31 SE SE01293/68A patent/SE346776B/xx unknown
- 1968-01-31 SE SE01296/68A patent/SE346777B/xx unknown
- 1968-01-31 SE SE01295/68A patent/SE346779B/xx unknown
-
1969
- 1969-09-22 FI FI269869A patent/FI52974C/fi active
-
1970
- 1970-12-07 NL NL7017830A patent/NL7017830A/en unknown
-
1971
- 1971-01-16 CY CY57271A patent/CY572A/en unknown
- 1971-06-01 DK DK267371A patent/DK129032B/en unknown
-
1972
- 1972-11-29 DK DK596872A patent/DK131988C/en active
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