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NL7016630A - Sweet aspartylaminoacid esters prepn - Google Patents

Sweet aspartylaminoacid esters prepn

Info

Publication number
NL7016630A
NL7016630A NL7016630A NL7016630A NL7016630A NL 7016630 A NL7016630 A NL 7016630A NL 7016630 A NL7016630 A NL 7016630A NL 7016630 A NL7016630 A NL 7016630A NL 7016630 A NL7016630 A NL 7016630A
Authority
NL
Netherlands
Prior art keywords
aspartylaminoacid
esters
prepn
sweet
ester
Prior art date
Application number
NL7016630A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to NL7016630A priority Critical patent/NL7016630A/en
Priority to CH713671A priority patent/CH553751A/en
Priority to FR7117531A priority patent/FR2091628A5/fr
Priority to IT50379/71A priority patent/IT989588B/en
Priority to BE767299A priority patent/BE767299A/en
Priority to US00144639A priority patent/US3808190A/en
Priority to GB1582971*[A priority patent/GB1336650A/en
Priority to DE19712125065 priority patent/DE2125065A1/en
Priority to JP3397271A priority patent/JPS5336446B1/ja
Priority to SE7106515A priority patent/SE393602B/en
Publication of NL7016630A publication Critical patent/NL7016630A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • C07K5/06113Asp- or Asn-amino acid
    • C07K5/06121Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613Aspartame
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • A23L27/31Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Aspartylaminoacid esters are prepd. by reacting N-carbobenzoxyaspartic acid anhydride with an amino-acid ester salt in an inert polar solvent while adding an amount of base at least equivalent to the ester, isolating the N-carbobenzoxy-alpha- and/or beta-aspartylaminoacid ester and removing the protecting gp. Compared with the known method, this gives higher yields, suppresses the formation of diketopiperzines and gives products of high optical purity. The products are useful as sweeteners in foods, drinks and pharmaceuticals.
NL7016630A 1970-05-19 1970-11-13 Sweet aspartylaminoacid esters prepn NL7016630A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
NL7016630A NL7016630A (en) 1970-11-13 1970-11-13 Sweet aspartylaminoacid esters prepn
CH713671A CH553751A (en) 1970-05-19 1971-05-13 METHOD FOR PRODUCING ASPARTYLAMINO ACID ESTERS.
FR7117531A FR2091628A5 (en) 1970-05-19 1971-05-14
IT50379/71A IT989588B (en) 1970-05-19 1971-05-17 PROCEDURE FOR THE PRODUCTION OF ASPARAGIL AMINO ACID ESTERS AND PRODUCT OBTAINED
BE767299A BE767299A (en) 1970-05-19 1971-05-18 PROCESS FOR THE PREPARATION OF ASPARTYL-AMINO-ACID ESTERS
US00144639A US3808190A (en) 1970-05-19 1971-05-18 Process for the preparation of aspartyl dipeptide esters involving little racemization
GB1582971*[A GB1336650A (en) 1970-05-19 1971-05-19 Process for the preparation of aspartyl aminoacid esters involving little racemization
DE19712125065 DE2125065A1 (en) 1970-05-19 1971-05-19 Process for the preparation of aspartic amino acid esters
JP3397271A JPS5336446B1 (en) 1970-05-19 1971-05-19
SE7106515A SE393602B (en) 1970-05-19 1971-05-19 PROCEDURE FOR THE PREPARATION OF ALFA ASPARTYL-AMINO ACID ESTERS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7016630A NL7016630A (en) 1970-11-13 1970-11-13 Sweet aspartylaminoacid esters prepn

Publications (1)

Publication Number Publication Date
NL7016630A true NL7016630A (en) 1972-05-16

Family

ID=19811549

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7016630A NL7016630A (en) 1970-05-19 1970-11-13 Sweet aspartylaminoacid esters prepn

Country Status (1)

Country Link
NL (1) NL7016630A (en)

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Legal Events

Date Code Title Description
BI The patent application has been withdrawn