NL300111I2 - 7-(1-Pyrroldinyl)-3-chinolon- en -naftyridoncarbonzuur-derivaten. - Google Patents

7-(1-Pyrroldinyl)-3-chinolon- en -naftyridoncarbonzuur-derivaten.

Info

Publication number: NL300111I2
Authority: NL; Netherlands
Prior art keywords: alkyl; halo; oxo; methyl; formula
Prior art date: 1988-07-15

Application number

NL300111C

Other languages

English (en)

Other versions

NL300111I1 (nl

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-07-15

Filing date

2003-01-20

Publication date

2003-07-01

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25870143&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL300111(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-01-20 Application filed by Bayer Ag filed Critical Bayer Ag

2003-04-01 Publication of NL300111I1 publication Critical patent/NL300111I1/nl

2003-07-01 Publication of NL300111I2 publication Critical patent/NL300111I2/nl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Quinoline Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Fodder In General (AREA)
Pyrrole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Amplifiers (AREA)
Separation Using Semi-Permeable Membranes (AREA)

NL300111C 1988-07-15 2003-01-20 7-(1-Pyrroldinyl)-3-chinolon- en -naftyridoncarbonzuur-derivaten. NL300111I2 (nl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3824072		1988-07-15
DE3906365A DE3906365A1 (de)	1988-07-15	1989-03-01	7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe

Publications (2)

Publication Number	Publication Date
NL300111I1 NL300111I1 (nl)	2003-04-01
NL300111I2 true NL300111I2 (nl)	2003-07-01

Family

ID=25870143

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL300111C NL300111I2 (nl)	1988-07-15	2003-01-20	7-(1-Pyrroldinyl)-3-chinolon- en -naftyridoncarbonzuur-derivaten.

Country Status (24)

Country	Link
US (4)	US4990517A (nl)
EP (2)	EP0350733B1 (nl)
JP (2)	JP2771853B2 (nl)
KR (1)	KR0156238B1 (nl)
CN (3)	CN1027165C (nl)
AT (2)	ATE135354T1 (nl)
AU (5)	AU616277B2 (nl)
CA (1)	CA1340114C (nl)
CY (1)	CY2111B1 (nl)
DE (4)	DE3906365A1 (nl)
DK (1)	DK170404B1 (nl)
ES (2)	ES2109219T3 (nl)
FI (1)	FI94251C (nl)
GR (1)	GR3024841T3 (nl)
HK (1)	HK1000938A1 (nl)
HU (3)	HU213099B (nl)
IE (1)	IE81144B1 (nl)
IL (1)	IL90940A (nl)
LU (1)	LU90645I2 (nl)
NL (1)	NL300111I2 (nl)
NO (1)	NO168889C (nl)
NZ (1)	NZ229914A (nl)
PT (1)	PT91165B (nl)
TW (1)	TW270119B (nl)

Families Citing this family (140)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5190955A (en) *	1987-01-28	1993-03-02	Bayer Aktiengesellschaft	Antibacterial 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids
JPH0674261B2 (ja) *	1988-06-21	1994-09-21	塩野義製薬株式会社	キノロンカルボン酸誘導体
DE3906365A1 (de) *	1988-07-15	1990-01-18	Bayer Ag	7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
DD285601A5 (de) *	1988-07-15	1990-12-19	Bayer Ag,De	Verfahren zur herstellung von 7-(1-pyrrolidinyl)-3-chinolon- und naphthyridoncarbonsaeure-derivaten
US5140033A (en) *	1989-04-03	1992-08-18	Bayer Aktiengesellschaft	Antibacterial 5-alkylquinolonecarboxylic acids
US5252734A (en) *	1989-04-03	1993-10-12	Bayer Aktiengesellschaft	Antibacterial 5-alkylquinolonecarboxylic acids
US5177210A (en) *	1989-04-17	1993-01-05	Bayer Aktiengesellschaft	Preparation of 2,7-diazabicyclo(3.3.0)octanes
DK0393424T3 (da) *	1989-04-17	1996-02-05	Bayer Ag	Fremgangsmåde til fremstilling af 2,7-diazabicyclo(3.3.0)octaner
US5241076A (en) *	1989-04-17	1993-08-31	Bayer Aktiengesellschaft	1,4-diazatricyclo [6.3.0.0]undecanes
SE8902076D0 (sv) *	1989-06-09	1989-06-09	Pharmacia Ab	Derivatives of quinoline-3-carboxanilide
US5214051A (en) *	1989-08-01	1993-05-25	Pfizer Inc.	Thiazolyl and oxazolyl[5,4-c]piperidyl-substituted quinolone-carboxylic acid and related analogs thereof having antibacterial properties are disclosed
US5266569A (en) *	1989-08-16	1993-11-30	Pfizer Inc.	Azatricyclo carboxylic acids useful as anti-bacterial agents
KR950005301B1 (ko) *	1990-09-04	1995-05-23	주식회사대웅제약	신규한 퀴놀론 카르복실산 유도체
DE4032560A1 (de) *	1990-10-13	1992-04-16	Bayer Ag	7-(2,7-diazabicyclo(3.3.0)octyl)-3-chinolon- und -naphtyridoncarbonsaeure-derivate
US5342846A (en) *	1990-12-05	1994-08-30	Synphar Laboratories, Inc.	7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents
ZA919601B (en) *	1990-12-05	1992-10-28	Synphar Lab Inc	7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds useful as antibacterial agents
ATE196135T1 (de) *	1991-05-28	2000-09-15	Daiichi Seiyaku Co	Pyridoncarbonsäurederivate
DE4120646A1 (de) *	1991-06-22	1992-12-24	Bayer Ag	7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate
DE4121214A1 (de) *	1991-06-27	1993-01-14	Bayer Ag	7-azaisoindolinyl-chinolon- und -naphthyridoncarbonsaeure-derivate
US5468742A (en) *	1991-07-19	1995-11-21	Bayer Aktiengesellschaft	8-vinyl- and 9-ethinyl-quinolone-carboxylic acids
KR950014567B1 (ko) *	1991-08-01	1995-12-08	주식회사대웅제약	신규한 퀴놀론 카르복실산 유도체
EP0549857A1 (en) *	1991-12-31	1993-07-07	Korea Research Institute Of Chemical Technology	Antibacterial quinolone carboxylic acid derivatives
US6004956A (en) *	1992-01-10	1999-12-21	Bayer Aktiengesellschaft	Enantiomerically pure 2-oxa-5,8-dizaabicyclo[4.3.0] nonanes and process for their preparation
DE4200415A1 (de) *	1992-01-10	1993-07-15	Bayer Ag	Enantiomerenreine 2-oxa-5,8-diazabicyclo(4.3.0)nonane sowie verfahren zu ihrer herstellung
TW209865B (nl) *	1992-01-10	1993-07-21	Bayer Ag
KR960003616B1 (ko) *	1992-07-23	1996-03-20	재단법인 한국화학연구소	우수한 항균작용을 갖는 신규한 피리돈 카르복실산 유도체 및 그의 제조방법
KR960003611B1 (ko) *	1992-07-23	1996-03-20	재단법인 한국화학연구소	신규한 디아자비시클로 알켄 유도체 및 그의 제조방법
DE4232172A1 (de) *	1992-09-25	1994-03-31	Bayer Ag	7-(Aminomethyl-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)chinolon- und Naphthyridoncarbonsäure-Derivate
DE4234078A1 (de) *	1992-10-09	1994-04-14	Bayer Ag	Chinoloncarbonsäuren
DE4234330A1 (de) *	1992-10-12	1994-04-14	Bayer Ag	Chinoloncarbonsäuren
EG20543A (en) *	1992-10-30	1999-07-31	Procter & Gamble	Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones
KR940014395A (ko) *	1992-12-09	1994-07-18	강박광	신규한 퀴놀론 유도체 및 그의 제조방법
CA2112165C (en) *	1992-12-25	2003-04-08	Makoto Takemura	Bicyclic amine derivatives
KR0148277B1 (ko) *	1993-01-18	1998-11-02	채영복	신규한 플루오르퀴놀론계 유도체 및 그의 제조방법
WO1994025464A1 (en) *	1993-04-24	1994-11-10	Korea Research Institute Of Chemical Technology	Novel quinolone carboxylic acid derivatives and process for preparing the same
TW252107B (nl) *	1993-08-27	1995-07-21	Hokuriku Pharmacetical Co Ltd
DE4329600A1 (de) *	1993-09-02	1995-03-09	Bayer Ag	Pyrido [1,2,3-d,e] [1,3,4] benzoxadiazinderivate
KR950018003A (ko) *	1993-12-09	1995-07-22	스미스클라인 비참 피엘씨	신규한 퀴놀론 유도체 및 그의 제조 방법
DE4342186A1 (de) *	1993-12-10	1995-06-14	Bayer Ag	Eintopfverfahren zur Herstellung von 3-Chinoloncarbonsäurederivaten
DE4416622A1 (de) *	1994-05-11	1995-11-16	Bayer Ag	8-Amino-10-(azabicycloalkyl)-pyrido[1,2,3-d.e] [1,3,4]benzoxa-diazinderivate
AU679859B2 (en) *	1994-06-14	1997-07-10	Dainippon Sumitomo Pharma Co., Ltd.	Novel compound, process for producing the same, and antitumor agent
DE19500792A1 (de) *	1995-01-13	1996-07-18	Bayer Ag	Chinolon- und Naphthyridoncarbonsäure-Derivate
CN1183778A (zh) *	1995-01-24	1998-06-03	北陆制药株式会社	喹啉羧酸衍生物
US6024979A (en) *	1995-06-06	2000-02-15	Solvay Animal Health, Inc.	Oral veterinary composition containing a fluoroquinolone antibacterial agent possessing superior absorption properties and an extended duration of therapeutic antimicrobial blood levels, and a method of treating a microbial infection in a ruminant
WO1997031001A1 (de) *	1996-02-23	1997-08-28	Bayer Aktiengesellschaft	Gegebenenfalls substituierte 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre derivate
US5703244A (en) *	1996-11-21	1997-12-30	Abbott Laboratories	Process for preparation of chiral 3-amino-pyrrolidine and analogous bicyclic compounds
US5874554A (en) *	1996-12-13	1999-02-23	Incyte Pharmaceuticals, Inc.	Methods and solvent vehicles for reagent delivery in oligonucleotide synthesis using automated pulse jetting devices
DE19652239A1 (de) *	1996-12-16	1998-06-18	Bayer Ag	Verwendung von 7-(2-Oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-chinolon- und -naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen
KR100219327B1 (ko) *	1997-08-09	1999-09-01	이서봉	퀴놀론 카르복실산 유도체
US6387928B1 (en)	1997-09-15	2002-05-14	The Procter & Gamble Co.	Antimicrobial quinolones, their compositions and uses
IL135036A0 (en)	1997-09-15	2001-05-20	Procter & Gamble	Antimicrobial quinolones, their compositions and uses
DE59804823D1 (de) *	1997-09-25	2002-08-22	Bayer Ag	Arzneimittelformulierung mit kontrollierter wirkstofffreisetzung
DE19751948A1 (de)	1997-11-24	1999-05-27	Bayer Ag	Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
EP1088825B9 (en) *	1998-06-17	2004-09-15	Daiichi Pharmaceutical Co., Ltd.	Enantiomerically pure substituted oxaaza compounds, salts of the same, and processes for the preparation of both
AR020661A1 (es) *	1998-09-30	2002-05-22	Alcon Lab Inc	Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
US6395746B1 (en)	1998-09-30	2002-05-28	Alcon Manufacturing, Ltd.	Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6716830B2 (en)	1998-09-30	2004-04-06	Alcon, Inc.	Ophthalmic antibiotic compositions containing moxifloxacin
US6509327B1 (en)	1998-09-30	2003-01-21	Alcon Manufacturing, Ltd.	Compositions and methods for treating otic, ophthalmic and nasal infections
US6197974B1 (en)	1998-10-26	2001-03-06	Abbott Laboratories	Enantioselective synthesis of 3-aminopyrrolidines
WO2000027398A1 (de) *	1998-11-10	2000-05-18	Bayer Aktiengesellschaft	Pharmazeutische zubereitung von moxifloxacin
DE19854355A1 (de) *	1998-11-25	2000-05-31	Bayer Ag	Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854356A1 (de) *	1998-11-25	2000-05-31	Bayer Ag	Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854357A1 (de) *	1998-11-25	2000-05-31	Bayer Ag	Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19927412A1 (de)	1999-06-16	2000-12-21	Bayer Ag	Verfahren zur Enantiomerenanreicherung von cis-8-Benzyl-7,9-dioxo-2,8-diazabicyclo [4.3.0]nonan
DE19931115A1 (de)	1999-07-06	2001-01-11	Bayer Ag	Racemisierung von R, S-Dioxo-Benzylpyrrolopiperidin
US6552020B1 (en) *	1999-07-30	2003-04-22	Allergan, Inc.	Compositions including antibiotics and methods for using same
DE19937115A1 (de)	1999-08-06	2001-02-08	Bayer Ag	Wäßrige Arzneimittelformulierung von Moxifloxacin oder Salzen davon
DE19937116A1 (de) *	1999-08-06	2001-02-08	Bayer Ag	Moxifloxacin Kochsalzformulierung
SE9903290D0 (sv) *	1999-09-15	1999-09-15	Astra Pharma Prod	Novel compounds
DE19962470A1 (de) *	1999-12-22	2001-07-12	Schulz Hans Herrmann	Verwendung von Chemotherapeutika
DK1262477T3 (da) *	2000-02-09	2008-12-01	Daiichi Sankyo Co Ltd	Antibakterielle midler, der er virksomme mod syrefaste bakterier og indeholder pyridoncarboxylsyrer som aktiv ingrediens
IL151451A0 (en) *	2000-02-25	2003-04-10	Daiichi Seiyaku Co	Process for producing quinolonecarboxylic acids and intermediates thereof
DE10022369A1 (de)	2000-05-08	2001-11-15	Bayer Ag	Verfahren zur Herstellung von Piperidinen
US6608078B2 (en)	2000-05-08	2003-08-19	Wockhardt Limited	Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment
US7098219B2 (en)	2000-08-01	2006-08-29	Wockhart Limited	Inhibitors of cellular efflux pumps of microbes
US6579904B1 (en)	2000-09-22	2003-06-17	K.E.R. Associates, Inc.	Process for making betaine transition metal complexes for use in animal feed supplements and compositions thereof
WO2002070523A1 (en) *	2001-03-07	2002-09-12	Pfizer Products Inc.	Modulators of chemokine receptor activity
JPWO2002083636A1 (ja) *	2001-04-06	2004-08-05	エーザイ株式会社	ピロリジン誘導体およびその製造方法
US6878713B2 (en)	2001-04-25	2005-04-12	Wockhardt Limited	Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6964966B2 (en)	2001-04-25	2005-11-15	Wockhardt Limited	Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6664267B1 (en)	2002-05-28	2003-12-16	Wockhardt Limited	Crystalline fluoroquinolone arginine salt form
DE10226923A1 (de) *	2002-06-17	2003-12-24	Bayer Ag	Verfahren zur Enantiomerenanreicherung von cis-8-Benzyl-7,9-dioxo-2,8-diazabicyclo[4.3.0]nonan
AU2003278418A1 (en) *	2002-10-31	2004-05-25	Ranbaxy Laboratories Limited	Amorphous moxifloxacin hydrochloride
RU2373937C9 (ru) *	2003-02-10	2010-07-27	Байер Шеринг Фарма Акциенгезельшафт	Лечение бактериальных заболеваний органов дыхания путем местного применения фторхинолонов
JP4608922B2 (ja) *	2003-06-27	2011-01-12	東レ・ファインケミカル株式会社	含窒素複素環化合物の製造方法
EP1663226A1 (en) *	2003-09-03	2006-06-07	Ranbaxy Laboratories Limited	Pharmaceutical compositions of moxifloxacin and processes for their preparation
AU2003304460A1 (en)	2003-09-04	2005-03-29	Wockhardt Limited	Benzoquinolizine-2-carboxylic acid arginine salt tetrahydrate
ITMI20032259A1 (it) *	2003-11-20	2005-05-21	Chemi Spa	Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione
JP4573223B2 (ja) *	2004-01-23	2010-11-04	東レ・ファインケミカル株式会社	光学活性ｔｒａｎｓ−４−アミノ−１−ベンジル−３−ピロリジノールの製造方法
JP2005220081A (ja) *	2004-02-06	2005-08-18	Toray Fine Chemicals Co Ltd	ｃｉｓ−４−アミノ−１−ベンジル−３−ピロリジノールの製造方法およびピロリジン誘導体
US7728031B2 (en)	2006-02-24	2010-06-01	Abbott Laboratories	Octahydro-pyrrolo[3,4-b]pyrrole derivatives
JP4770516B2 (ja) *	2006-02-28	2011-09-14	パナソニック株式会社	プラズマディスプレイパネル
MX2008012488A (es) *	2006-03-28	2008-10-10	Procter & Gamble	Un proceso de acoplamiento para preparar intermedios de quinolona.
MY148393A (en) *	2006-03-28	2013-04-15	Taigen Biotechnology Co Ltd	Malate salts, and polymorphs of (3s, 5s)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
GB0612422D0 (en) *	2006-06-23	2006-08-02	Generics Uk Ltd	Novel hydrate form
CA2669427A1 (en)	2006-11-13	2008-05-22	Cipla Limited	Process for the synthesis of moxifloxacin hydrochloride
US20080139574A1 (en)	2006-11-30	2008-06-12	Cadila Healthcare Limited	Novel quinoline derivatives
US7692015B2 (en) *	2007-01-05	2010-04-06	Zheqing Wang	Economical process for preparing (S, S)-2, 8-diazabicyclo[4.3.0]nonane and its enantiomer
US7902227B2 (en) *	2007-07-27	2011-03-08	Janssen Pharmaceutica Nv.	C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents
WO2009036132A1 (en)	2007-09-11	2009-03-19	Abbott Laboratories	Octahydro-pyrrolo[3,4-b]pyrrole n-oxides
US7888370B2 (en) *	2007-11-27	2011-02-15	Alcon Research, Ltd.	Topical ophthalmic or otic solution formulations containing moxifloxacin hydrochloride and dexamethasone phosphate
EP2083010A1 (en)	2008-01-08	2009-07-29	Chemo Ibérica, S.A.	Polymorphic Forms of Moxifloxacin hydrochloride and processes for preparation thereof
AU2009214461A1 (en) *	2008-02-15	2009-08-20	Alcon Research, Ltd.	Fluoroquinolone derivatives for ophthalmic applications
FR2928150A1 (fr) *	2008-02-29	2009-09-04	Vetoquinol Sa Sa	Nouveaux derives 7-substitues de 3-carboxy-oxadiazino-quinolones, leur preparation et leur application comme anti-bacteriens
ATE473977T1 (de)	2008-04-30	2010-07-15	Univ Duisburg Essen	Indolä2,3-bü-, indenä1,2-bü- und indenä2,1- büpyridoä2,3-fü quinoxalin-3-carboxylsäuren und ester, verfahren zu ihrer herstellung und ihre verwendung als antivirus- und antitumormittel
EP2145891A1 (en)	2008-07-09	2010-01-20	Vetoquinol S.A.	9-substituted-5-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials
EP2154137A1 (en)	2008-08-04	2010-02-17	Chemo Ibérica, S.A.	Crystalline form of moxifloxacin base
CN101429199B (zh) *	2008-09-08	2010-12-15	华东师范大学	外消旋顺式8-苄基-7,9-二氧代-2,8-二氮杂双环[4.3.0]壬烷的制备方法
ES2391132T3 (es)	2008-10-09	2012-11-21	Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi	Uso de disolventes orgánicos en la granulación húmeda de moxifloxacino
ES2467105T5 (es)	2008-12-08	2017-12-05	Ratiopharm Gmbh	Moxifloxacino compactado
WO2010093341A1 (en) *	2009-02-10	2010-08-19	Janssen Pharmaceutica N.V.	C-7 isoxazolinyl quinolone/naphthyridine derivatives useful as antibacterial agents
IT1393337B1 (it)	2009-03-06	2012-04-20	Italiana Sint Spa	Sintesi di (4as, 7as)-ottaidro-1h-pirrolo[3,4-b]piridina
EP2423211B1 (en) *	2009-04-20	2014-04-16	Kaneka Corporation	Processes for producing (1s,6s)- or (1r,6r)-cis-2,8-diazabicyclo[4.3.0]nonane and intermediate thereof
NZ596492A (en)	2009-05-15	2013-08-30	Redx Pharma Ltd	Redox drug derivatives
CN102675308A (zh) *	2011-03-17	2012-09-19	苏州中科天马肽工程中心有限公司	一种制备8-苄基-2,8-二氮杂二环[4.3.0]壬烷的方法
RS55582B1 (sr) *	2011-05-13	2017-06-30	Array Biopharma Inc	Jedinjenja pirolidinil uree, pirolidinil tiouree i pirolidinil guanidina kao inhibitori trka kinaze
CN102964346B (zh) *	2011-09-01	2015-04-22	中国中化股份有限公司	一种制备(S,S)-八氢-6H-吡咯并[3,4-b]吡啶的方法
WO2013056165A1 (en)	2011-10-12	2013-04-18	Yoseph Yaacobi	Contact lens cleaning systems
CN102399219A (zh) *	2011-11-18	2012-04-04	太仓市运通化工厂	一种盐酸莫西沙星中间体的制备方法
BRPI1106900A2 (pt)	2011-12-26	2013-11-05	Ems Sa	Composição farmacêutica sólida compreendendo antibótico da familia das quinolonas e processo de sua obtenção
CA2893534A1 (en)	2012-12-04	2014-06-12	Mankind Research Centre	An improved process for the preparation of moxifloxacin hydrochloride
CN105143219A (zh)	2012-12-21	2015-12-09	曼康德研究中心	用于制备作为氮杂双环吡啶衍生物的中间体的(s,s)-6-苄基八氢-1h-吡咯并[3,4-b]吡啶的方法
JP6056036B2 (ja)	2013-01-31	2017-01-11	高砂香料工業株式会社	光学活性２−アリールピペリジニウム塩の製造方法
RU2561037C2 (ru) *	2013-02-07	2015-08-20	Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН")	Антибактериальная фармацевтическая композиция и способ ее получения
GR1008168B (el)	2013-03-14	2014-04-08	"Φαρματεν Α.Β.Ε.Ε.",	Παρεντερικο σκευασμα αντιβακτηριακου παραγοντα φθοριοκινολονης και μεθοδος για την παρασκευη αυτου
BR112015023044A8 (pt)	2013-03-15	2021-09-28	Melinta Subsidiary Corp	Métodos para tratar infecções em pacientes acima do peso e obesos com o uso de antibióticos
MX2016001912A (es)	2013-08-12	2016-06-02	Novartis Ag	Metodos para tratar infecciones oticas luego de la colocacion de un tubo de timpanostomia.
GB201322334D0 (en)	2013-12-17	2014-01-29	Agency Science Tech & Res	Maleimide derivatives as modulators of WNT pathway
RU2558932C1 (ru) *	2014-05-22	2015-08-10	Открытое Акционерное Общество "Татхимфармпрепараты"	Фармацевтическая композиция моксифлоксацина и способ ее приготовления
EP2957561A1 (en)	2014-06-18	2015-12-23	Université Paris 6 Pierre et Marie Curie UPMC	Novel fluoroquinolones and use thereof to treat bacterial infections
EP3692991A1 (de)	2015-06-09	2020-08-12	Bayer Pharma Aktiengesellschaft	Positiv allosterische modulatoren des muskarinergen m2 rezeptors
US11452732B2 (en)	2015-09-05	2022-09-27	Randal Davis	Homogeneous ophthalmic composition
US10130639B1 (en)	2015-09-05	2018-11-20	Randal Davis	Homogeneous ophthalmic composition
WO2018011017A1 (de)	2016-07-11	2018-01-18	Bayer Pharma Aktiengesellschaft	7-substituierte 1-pyridyl-naphthyridin-3-carbonsäureamide und ihre verwendung
CN107602465A (zh) *	2016-07-12	2018-01-19	重庆大学	一种喹诺酮类衍生物及其应用
EP3296298A1 (de) *	2016-09-14	2018-03-21	Bayer Pharma Aktiengesellschaft	7-substituierte 1-aryl-naphthyridin-3-carbonsäureamide und ihre verwendung
JOP20190045A1 (ar) *	2016-09-14	2019-03-14	Bayer Ag	مركبات أميد حمض 1- أريل-نفثيريدين-3-كربوكسيليك مستبدلة في الموضع 7 واستخدامها.
PT3512849T (pt) *	2016-12-06	2021-09-08	Bayer Pharma AG	1-arilnaftiridina-3-carboxamidas 7-substituídas e sua utilização
CN113527288A (zh) *	2020-04-16	2021-10-22	沈阳药科大学	喹诺酮羧酸衍生物或二氮杂萘酮羧酸衍生物的制备方法
EP4164626A4 (en) *	2020-06-15	2024-07-03	Mylan Laboratories Ltd.	Combination antibacterial composition and method for antibacterial therapy

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE438819B (sv) *	1978-06-19	1985-05-13	Sun Chemical Corp	Anordning for applicering av flerfergsbilder pa cylindriska eller stympat koniska foremal
JPS5880989A (ja) *	1981-11-06	1983-05-16	Mitsubishi Electric Corp	静止画テレビジヨン伝送装置の監視制御装置
US4665079A (en) *	1984-02-17	1987-05-12	Warner-Lambert Company	Antibacterial agents
US4777175A (en) *	1982-09-09	1988-10-11	Warner-Lambert Company	Antibacterial agents
IE55898B1 (en) *	1982-09-09	1991-02-14	Warner Lambert Co	Antibacterial agents
JPS60126284A (ja) *	1983-12-09	1985-07-05	Dainippon Pharmaceut Co Ltd	ピリドンカルボン酸誘導体およびその塩
IT1173374B (it) *	1984-02-24	1987-06-24	Mediolanum Farmaceutici Srl	Derivati pirido-benzotiazinici ad elevata attivita' antimicrobica
US4571396A (en) *	1984-04-16	1986-02-18	Warner-Lambert Company	Antibacterial agents
US4698350A (en) *	1984-09-17	1987-10-06	Sterling Drug Inc.	1-ethyl-6-fluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarboxylic acid and antibacterial use thereof
US4657913A (en) *	1985-04-18	1987-04-14	Warner-Lambert Company	Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
US4772706A (en) *	1986-01-13	1988-09-20	Warner-Lambert Company	Process for quinoline-3-carboxylic acid antibacterial agents
JPS62215572A (ja) *	1986-03-17	1987-09-22	Kyorin Pharmaceut Co Ltd	キノロンカルボン酸誘導体
JPS63198664A (ja) *	1986-03-31	1988-08-17	Sankyo Co Ltd	キノロンカルボン酸誘導体
DK164287A (da) *	1986-03-31	1987-10-01	Sankyo Co	Quinolin-3-carboxylsyrederivater og fremgangsmaade til fremstilling deraf og deres anvendelse
US4771055A (en) *	1986-07-28	1988-09-13	Warner-Lambert Company	7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acids
JPH0618781B2 (ja) *	1986-10-18	1994-03-16	中外製薬株式会社	感染症治療剤
JPS63179856A (ja) *	1987-01-21	1988-07-23	Kyorin Pharmaceut Co Ltd	キノロンカルボン酸誘導体の製造方法並びにその中間体
JPS63297366A (ja) *	1987-05-29	1988-12-05	Sankyo Co Ltd	８−アルコキシキノロンカルボン酸誘導体
JPH0784423B2 (ja) *	1987-06-18	1995-09-13	宇部興産株式会社	３−アミノ−２−置換ベンゾイルアクリル酸誘導体
JPS643181A (en) *	1987-06-23	1989-01-06	Sankyo Co Ltd	Pyridonecarboxylic acid derivative
JPS649992A (en) *	1987-06-30	1989-01-13	Dainippon Pharmaceutical Co	1,8-crosslinked quinolincarboxylic acid derivative, ester thereof and salt thereof
JPH0676400B2 (ja) *	1987-08-25	1994-09-28	大日本製薬株式会社	新規ピリドンカルボン酸誘導体、そのエステルおよびその塩
US5075319A (en) *	1987-09-08	1991-12-24	Sterling Drug Inc.	Pyridinyl-quinolone compounds, their preparation and use
US4889857A (en) *	1987-10-12	1989-12-26	Yoshitomi Pharmaceutical Industries, Ltd.	Quinolonecarboxylic acid compounds and pharmaceutical use thereof
US4859776A (en) *	1988-03-11	1989-08-22	Abbott Laboratories	(S)-7-(3-aminopyrrolidin-1-yl)-1-(ortho, para-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid and method for its preparation
JPH0674261B2 (ja) *	1988-06-21	1994-09-21	塩野義製薬株式会社	キノロンカルボン酸誘導体
DD285601A5 (de) *	1988-07-15	1990-12-19	Bayer Ag,De	Verfahren zur herstellung von 7-(1-pyrrolidinyl)-3-chinolon- und naphthyridoncarbonsaeure-derivaten
DE3906365A1 (de) *	1988-07-15	1990-01-18	Bayer Ag	7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
AU618823B2 (en) *	1988-07-20	1992-01-09	Sankyo Company Limited	4-oxoquinoline-3-carboxylic acid derivatives, their preparation and their use
JPH0259388A (ja) *	1988-08-25	1990-02-28	Canon Inc	中間調画像記録方法
EP0443498A1 (en) *	1990-02-19	1991-08-28	Kyorin Pharmaceutical Co., Ltd.	Isoindoline derivatives
DE4301246A1 (de) *	1993-01-19	1994-07-21	Bayer Ag	Chinolon- und Naphthyridoncarbonsäurederivate

1989
- 1989-03-01 DE DE3906365A patent/DE3906365A1/de not_active Withdrawn
- 1989-06-19 AU AU36594/89A patent/AU616277B2/en not_active Expired
- 1989-06-29 NO NO892715A patent/NO168889C/no not_active IP Right Cessation
- 1989-06-30 AT AT8989111950T patent/ATE135354T1/de not_active IP Right Cessation
- 1989-06-30 CN CN89104574A patent/CN1027165C/zh not_active Expired - Lifetime
- 1989-06-30 ES ES89111950T patent/ES2109219T3/es not_active Expired - Lifetime
- 1989-06-30 US US07/375,434 patent/US4990517A/en not_active Expired - Lifetime
- 1989-06-30 DE DE58909622T patent/DE58909622D1/de not_active Expired - Lifetime
- 1989-06-30 DE DE1999175060 patent/DE19975060I2/de active Active
- 1989-06-30 EP EP89111950A patent/EP0350733B1/de not_active Expired - Lifetime
- 1989-06-30 AT AT96113744T patent/ATE292127T1/de not_active IP Right Cessation
- 1989-06-30 ES ES96113744T patent/ES2240984T4/es not_active Expired - Lifetime
- 1989-06-30 DE DE58909894T patent/DE58909894D1/de not_active Expired - Lifetime
- 1989-06-30 EP EP96113744A patent/EP0757990B1/de not_active Expired - Lifetime
- 1989-07-12 IL IL9094089A patent/IL90940A/en unknown
- 1989-07-12 JP JP1178218A patent/JP2771853B2/ja not_active Expired - Lifetime
- 1989-07-12 NZ NZ229914A patent/NZ229914A/en unknown
- 1989-07-13 FI FI893403A patent/FI94251C/fi active IP Right Grant
- 1989-07-13 PT PT91165A patent/PT91165B/pt not_active IP Right Cessation
- 1989-07-13 CA CA000605572A patent/CA1340114C/en not_active Expired - Lifetime
- 1989-07-14 HU HU9301002A patent/HU213099B/hu unknown
- 1989-07-14 HU HU893578A patent/HU208130B/hu unknown
- 1989-07-14 IE IE229389A patent/IE81144B1/en not_active IP Right Cessation
- 1989-07-14 DK DK350089A patent/DK170404B1/da not_active IP Right Cessation
- 1989-07-15 KR KR1019890010217A patent/KR0156238B1/ko not_active Expired - Lifetime
- 1989-07-18 TW TW078105496A patent/TW270119B/zh active
1990
- 1990-09-10 US US07/580,906 patent/US5059597A/en not_active Expired - Lifetime
1991
- 1991-07-30 US US07/737,631 patent/US5416096A/en not_active Expired - Lifetime
1992
- 1992-01-16 AU AU10283/92A patent/AU650316B2/en not_active Expired
- 1992-09-22 AU AU25286/92A patent/AU658667B2/en not_active Expired
1994
- 1994-01-21 CN CN94100328A patent/CN1036005C/zh not_active Expired - Lifetime
- 1994-04-19 AU AU60557/94A patent/AU668287B2/en not_active Expired
- 1994-09-15 AU AU72991/94A patent/AU671386B2/en not_active Expired
1995
- 1995-03-20 US US08/406,448 patent/US5607942A/en not_active Expired - Lifetime
- 1995-06-26 HU HU95P/P00442P patent/HU211472A9/hu unknown
1996
- 1996-04-12 CN CN96103664A patent/CN1143080A/zh active Pending
1997
- 1997-09-24 GR GR970402480T patent/GR3024841T3/el unknown
- 1997-12-19 HK HK97102516A patent/HK1000938A1/xx not_active IP Right Cessation
1998
- 1998-01-08 JP JP10013154A patent/JP3001848B2/ja not_active Expired - Lifetime
- 1998-09-14 CY CY9800027A patent/CY2111B1/xx unknown
2000
- 2000-09-27 LU LU90645C patent/LU90645I2/fr unknown
2003
- 2003-01-20 NL NL300111C patent/NL300111I2/nl unknown

Also Published As

Publication number	Publication date
CA1340114C (en)	1998-11-03
DE3906365A1 (de)	1990-01-18
AU2528692A (en)	1992-11-26
NO168889B (no)	1992-01-06
AU616277B2 (en)	1991-10-24
US5416096A (en)	1995-05-16
FI893403A7 (fi)	1990-01-16
NZ229914A (en)	1992-03-26
ES2109219T3 (es)	1998-01-16
EP0757990B1 (de)	2005-03-30
AU6055794A (en)	1994-06-09
DK350089A (da)	1990-01-16
HU211472A9 (en)	1995-11-28
DE58909894D1 (de)	2005-05-04
PT91165A (pt)	1990-02-08
HK1000938A1 (en)	1998-05-08
HU9301002D0 (en)	1993-06-28
DK350089D0 (da)	1989-07-14
NO892715D0 (no)	1989-06-29
NO168889C (no)	1992-04-15
TW270119B (nl)	1996-02-11
KR900001699A (ko)	1990-02-27
AU671386B2 (en)	1996-08-22
ES2240984T4 (es)	2012-10-08
US5059597A (en)	1991-10-22
CN1143080A (zh)	1997-02-19
AU650316B2 (en)	1994-06-16
EP0350733B1 (de)	1997-08-20
HUT52087A (en)	1990-06-28
CN1036005C (zh)	1997-10-01
ATE135354T1 (de)	1996-03-15
FI893403A0 (fi)	1989-07-13
JP3001848B2 (ja)	2000-01-24
ES2240984T3 (es)	2005-10-16
ATE292127T1 (de)	2005-04-15
CN1097759A (zh)	1995-01-25
IL90940A (en)	1994-04-12
CN1039589A (zh)	1990-02-14
DE58909622D1 (de)	1997-09-25
HU208130B (en)	1993-08-30
IE892293L (en)	1990-01-15
HUT65936A (en)	1994-08-29
JPH10182600A (ja)	1998-07-07
AU7299194A (en)	1994-12-08
DE19975060I2 (de)	2004-10-14
KR0156238B1 (ko)	1998-11-16
JP2771853B2 (ja)	1998-07-02
JPH0269474A (ja)	1990-03-08
NL300111I1 (nl)	2003-04-01
AU1028392A (en)	1992-02-27
AU668287B2 (en)	1996-04-26
EP0350733A2 (de)	1990-01-17
NO892715L (no)	1990-01-16
GR3024841T3 (en)	1998-01-30
HU213099B (en)	1997-02-28
PT91165B (pt)	1995-03-01
FI94251B (fi)	1995-04-28
FI94251C (fi)	1995-08-10
IL90940A0 (en)	1990-02-09
IE81144B1 (en)	2000-05-03
DK170404B1 (da)	1995-08-21
EP0757990A1 (de)	1997-02-12
US5607942A (en)	1997-03-04
AU3659489A (en)	1990-03-15
CN1027165C (zh)	1994-12-28
CY2111B1 (en)	2002-04-26
US4990517A (en)	1991-02-05
AU658667B2 (en)	1995-04-27
EP0350733A3 (en)	1990-12-27
LU90645I2 (fr)	2000-12-27
IE970856A1 (en)	2000-02-23

Publication	Publication Date	Title
NL300111I2 (nl)	2003-07-01	7-(1-Pyrroldinyl)-3-chinolon- en -naftyridoncarbonzuur-derivaten.
NO931529L (no)	1993-10-29	Cykliske fruktopyranosesulfitter og -sulfater med antikonvulsiv effekt
FI814148L (fi)	1982-06-28	Nya trisubstituerade pyrimido/5,4-d/pyrimidiner deras framstaellning och deras anvaendning saosom laekemedel
DE3869886D1 (de)	1992-05-14	Tetracyclische chinazolinderivate, herstellung und verwendung.
YU46708B (sh)	1994-04-05	Postupak za dobijanje antibakterijskih derivata 9-dezoksi-9a-alil i propagril-9a-aza-9ahomoeritromicina
DE3880304D1 (de)	1993-05-19	2-hydroxy-3-aryloxy-propylaminderivate mit kardiovaskulaerer wirkung.
DE3875820D1 (de)	1992-12-17	Aromatische heterozyklische karbonsaeureamidabkoemmlinge, verfahren zur herstellung und arzneimittel, die diese enthalten.
FR2360305B1 (nl)	1980-04-18
IE802409L (en)	1978-02-04	2,3-alkylene bis (oxy) benzoic acids
JPS5328181A (en)	1978-03-16	Production of nove substituted 233alkylenebis oxy* benzoic acid