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NL300093I1 - Werkwijze voor de bereiding van organische oligosacchariden die met fragmenten van natuurlijke mucopolysacchariden overeenkomen, de aldus verkregen oligosacchariden en hun biologische toepassing. - Google Patents

Werkwijze voor de bereiding van organische oligosacchariden die met fragmenten van natuurlijke mucopolysacchariden overeenkomen, de aldus verkregen oligosacchariden en hun biologische toepassing.

Info

Publication number
NL300093I1
NL300093I1 NL300093C NL300093C NL300093I1 NL 300093 I1 NL300093 I1 NL 300093I1 NL 300093 C NL300093 C NL 300093C NL 300093 C NL300093 C NL 300093C NL 300093 I1 NL300093 I1 NL 300093I1
Authority
NL
Netherlands
Prior art keywords
oligosaccharides
fragments
organic
preparation
biological application
Prior art date
Application number
NL300093C
Other languages
English (en)
Other versions
NL300093I2 (nl
Original Assignee
Sanifori Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8200621A external-priority patent/FR2519987A1/fr
Priority claimed from FR8201575A external-priority patent/FR2520744A1/fr
Priority claimed from FR8202526A external-priority patent/FR2521566A1/fr
Priority claimed from FR8209392A external-priority patent/FR2527614A1/fr
Priority claimed from FR8210892A external-priority patent/FR2528854A1/fr
Priority claimed from FR8210891A external-priority patent/FR2528853A1/fr
Priority claimed from FR8211679A external-priority patent/FR2529557A1/fr
Priority claimed from FR8213804A external-priority patent/FR2531436A1/fr
Priority claimed from FR8215803A external-priority patent/FR2533219A1/fr
Priority claimed from FR8215804A external-priority patent/FR2533220A1/fr
Priority claimed from FR8218303A external-priority patent/FR2535306A1/fr
Application filed by Sanifori Synthelabo filed Critical Sanifori Synthelabo
Publication of NL300093I1 publication Critical patent/NL300093I1/nl
Publication of NL300093I2 publication Critical patent/NL300093I2/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078Degradation products
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/02Acyclic radicals
    • C07H7/033Uronic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04Cyclic acetals
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
NL300093C 1982-01-15 2002-07-09 Werkwijze voor de bereiding van organische oligosacchariden die met fragmenten van natuurlijke mucopolysacchariden overeenkomen, de aldus verkregen oligosacchariden en hun biologische toepasssing. NL300093I2 (nl)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
FR8200621A FR2519987A1 (fr) 1982-01-15 1982-01-15 Trisaccharides a structures d-glucosamine, acide d-glucuronique, d-glucosamine et leur preparation
FR8201575A FR2520744A1 (fr) 1982-02-01 1982-02-01 Nouveaux derives d'osides et leur preparation
FR8202526A FR2521566A1 (fr) 1982-02-16 1982-02-16 Nouveaux tetrasaccharides et leur preparation
FR8209392A FR2527614A1 (fr) 1982-05-28 1982-05-28 Nouveaux derives de disaccharides formes de motifs a structure respectivement glucosamine et acide uronique et leur preparation
FR8210892A FR2528854A1 (fr) 1982-06-22 1982-06-22 Nouveaux derives de tetrasaccharides et leur preparation
FR8210891A FR2528853A1 (fr) 1982-06-22 1982-06-22 Nouveaux trisaccharides a structure d-glucosamine, acide l-iduronique, d-glucosamine et leur preparation
FR8211679A FR2529557A1 (fr) 1982-07-02 1982-07-02 Nouveaux disaccharides contenant un motif a-l-idopyranose, et leur preparation
FR8213804A FR2531436A1 (fr) 1982-08-06 1982-08-06 Pentasaccharides substitues possedant des proprietes biologiques, leur preparation et leurs applications en tant que medicaments
FR8215803A FR2533219A1 (fr) 1982-09-20 1982-09-20 Nouveaux disaccharides formes de motifs a structure d-glucosamine et acide l-iduronique et procede pour leur preparation
FR8215804A FR2533220A1 (fr) 1982-09-20 1982-09-20 Nouveaux disaccharides formes de motifs a structure acide d-glucuronique et d-glucosamine et procede pour leur preparation
FR8218303A FR2535306A1 (fr) 1982-10-28 1982-10-28 Procede de synthese organique d'oligosaccharides correspondant a des fragments de muco-polysaccharides naturels, nouveaux oligosaccharides obtenus et leurs applications biologiques

Publications (2)

Publication Number Publication Date
NL300093I1 true NL300093I1 (nl) 2002-09-02
NL300093I2 NL300093I2 (nl) 2002-11-01

Family

ID=27581615

Family Applications (1)

Application Number Title Priority Date Filing Date
NL300093C NL300093I2 (nl) 1982-01-15 2002-07-09 Werkwijze voor de bereiding van organische oligosacchariden die met fragmenten van natuurlijke mucopolysacchariden overeenkomen, de aldus verkregen oligosacchariden en hun biologische toepasssing.

Country Status (4)

Country Link
EP (1) EP0084999B1 (nl)
AU (1) AU563351C (nl)
LU (1) LU90928I2 (nl)
NL (1) NL300093I2 (nl)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2535324A1 (fr) * 1982-10-27 1984-05-04 Choay Sa Station perfectionnee pour l'epuration d'eaux usees
US4801583A (en) * 1982-01-15 1989-01-31 Choay S.A. Oligosaccharides and their biological applications
FR2564468B1 (fr) * 1984-05-16 1994-12-23 Choay Sa Nouveaux oligosaccharides, leur preparation par voie de synthese et leurs applications biologiques
FR2548189B1 (fr) * 1983-07-01 1986-04-11 Choay Sa Nouveaux produits contenant des oligosaccharides, leur preparation et leurs applications biologiques et biochimiques
SE8501022L (sv) * 1985-03-01 1986-09-02 Pharmacia Ab Format alster och forfarande for dess framstellning
GB8519416D0 (en) * 1985-08-01 1985-09-04 Unilever Plc Oligosaccharides
EP0300099A1 (en) * 1987-07-20 1989-01-25 Akzo N.V. New pentasaccharides
EP0347964A1 (en) * 1988-06-21 1989-12-27 Akzo N.V. New oligosaccharides with internal spacer
JPH0296588A (ja) * 1988-09-29 1990-04-09 Rikagaku Kenkyusho 硫酸化オリゴ糖及びその関連物質
FR2636967B1 (fr) * 1988-09-29 1990-12-07 Sanofi Sa Procede de dosage de polyosides anioniques sulfates, et coffret pour la mise en oeuvre de ce procede
US5476924A (en) * 1989-01-27 1995-12-19 Duke University Protecting group for acetals and methods of using the same in the activation of saccharides
US5707973A (en) * 1991-04-23 1998-01-13 Rhone-Poulenc Rorer S.A. Sulfated polysaccharids for treatment or prevention of thromboses
CA2149116A1 (en) * 1992-11-10 1994-05-26 Irun R. Cohen Compositions for the regulation of cytokine activity
CA2199642C (en) * 1997-03-10 2001-05-08 Roger Cariou Compositions containing an association of aspirin and an anti-xa oligosaccharide and use of an anti-xa oligosaccharide optionally in combination with aspirin
JP2002503270A (ja) 1997-05-27 2002-01-29 アクゾ・ノベル・エヌ・ベー 体外血液回路における血餅形成を防止するためのオリゴ糖の使用
AUPO888497A0 (en) 1997-09-01 1997-09-25 Australian National University, The Use of sulfated oligosaccharides as inhibitors of cardiovascular disease
AUPO976897A0 (en) * 1997-10-14 1997-11-06 Australian National University, The Use of sulfated oligosaccharides in lowering blood triglyceride levels
FR2800074B1 (fr) * 1999-10-22 2001-12-21 Aventis Pharma Sa Nouveaux oligosaccharides, leur preparation et les compositions pharmaceutiques les contenant
FR2814463B1 (fr) * 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
CA2806723C (en) 2001-09-07 2015-12-29 Alchemia Limited Synthetic heparin pentasaccharides
CN1317287C (zh) * 2003-04-18 2007-05-23 山东大学 一种多硫酸寡糖及其制备方法
FR2874924B1 (fr) 2004-09-09 2006-12-01 Sanofi Aventis Sa Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
RU2538973C2 (ru) 2008-05-30 2015-01-10 Момента Фармасьютикалз, Инк. Структуры сахаридов и способы получения и применения таких структур
CN109734757B (zh) * 2019-03-11 2020-09-11 淮北师范大学 一种磺达肝癸钠注射液有关物质b的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1136620A (en) * 1979-01-08 1982-11-30 Ulf P.F. Lindahl Heparin fragments having selective anticoagulation activity
IL61201A (en) * 1979-10-05 1984-09-30 Choay Sa Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them
CA1171375A (en) * 1980-09-15 1984-07-24 Ulf P.F. Lindahl Oligosaccharides having selective anticoagulation activity
FR2504535B1 (fr) * 1981-04-28 1987-08-14 Choay Sa Disaccharides derives d'un acide uronique et d'une glucosamine et compositions pharmaceutiques les contenant pour le controle de la coagulation sanguine

Also Published As

Publication number Publication date
EP0084999A1 (fr) 1983-08-03
AU563351B2 (en) 1987-07-09
LU90928I2 (fr) 2002-08-07
NL300093I2 (nl) 2002-11-01
AU1039783A (en) 1983-07-21
AU563351C (en) 2003-06-19
EP0084999B1 (fr) 1988-04-13

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