NL194359C - Werkwijze voor het bereiden van een plantaardige samenstelling met ontstekingsremmende werking. - Google Patents
Werkwijze voor het bereiden van een plantaardige samenstelling met ontstekingsremmende werking. Download PDFInfo
- Publication number
- NL194359C NL194359C NL9201442A NL9201442A NL194359C NL 194359 C NL194359 C NL 194359C NL 9201442 A NL9201442 A NL 9201442A NL 9201442 A NL9201442 A NL 9201442A NL 194359 C NL194359 C NL 194359C
- Authority
- NL
- Netherlands
- Prior art keywords
- milk thistle
- inflammatory
- effective
- cases
- effect
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims description 28
- 230000003110 anti-inflammatory effect Effects 0.000 title claims description 11
- 238000004519 manufacturing process Methods 0.000 title claims description 7
- 235000013311 vegetables Nutrition 0.000 title description 7
- 230000000694 effects Effects 0.000 claims description 28
- 235000010841 Silybum marianum Nutrition 0.000 claims description 24
- 241000320380 Silybum Species 0.000 claims description 19
- 210000000440 neutrophil Anatomy 0.000 claims description 18
- 230000003078 antioxidant effect Effects 0.000 claims description 12
- 239000003814 drug Substances 0.000 claims description 12
- 229940088597 hormone Drugs 0.000 claims description 11
- 239000005556 hormone Substances 0.000 claims description 11
- 230000005855 radiation Effects 0.000 claims description 11
- 239000003963 antioxidant agent Substances 0.000 claims description 10
- 230000002757 inflammatory effect Effects 0.000 claims description 10
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 9
- UREBDLICKHMUKA-DVTGEIKXSA-N betamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-DVTGEIKXSA-N 0.000 claims description 9
- 210000004698 lymphocyte Anatomy 0.000 claims description 9
- 239000001301 oxygen Substances 0.000 claims description 9
- 229910052760 oxygen Inorganic materials 0.000 claims description 9
- 238000012360 testing method Methods 0.000 claims description 9
- 241000196324 Embryophyta Species 0.000 claims description 8
- 240000006439 Aspergillus oryzae Species 0.000 claims description 6
- 235000002247 Aspergillus oryzae Nutrition 0.000 claims description 6
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- 230000001684 chronic effect Effects 0.000 claims description 6
- 208000037922 refractory disease Diseases 0.000 claims description 6
- 244000272459 Silybum marianum Species 0.000 claims description 5
- 229940124599 anti-inflammatory drug Drugs 0.000 claims description 5
- KPHWPUGNDIVLNH-UHFFFAOYSA-M diclofenac sodium Chemical compound [Na+].[O-]C(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl KPHWPUGNDIVLNH-UHFFFAOYSA-M 0.000 claims description 5
- 238000006073 displacement reaction Methods 0.000 claims description 5
- HYYBABOKPJLUIN-UHFFFAOYSA-N mefenamic acid Chemical compound CC1=CC=CC(NC=2C(=CC=CC=2)C(O)=O)=C1C HYYBABOKPJLUIN-UHFFFAOYSA-N 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
- 229940063674 voltaren Drugs 0.000 claims description 5
- 208000027496 Behcet disease Diseases 0.000 claims description 4
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims description 4
- 206010009900 Colitis ulcerative Diseases 0.000 claims description 4
- 201000003066 Diffuse Scleroderma Diseases 0.000 claims description 4
- 201000006704 Ulcerative Colitis Diseases 0.000 claims description 4
- 229940121363 anti-inflammatory agent Drugs 0.000 claims description 4
- 239000002260 anti-inflammatory agent Substances 0.000 claims description 4
- 229910001424 calcium ion Inorganic materials 0.000 claims description 4
- 201000001981 dermatomyositis Diseases 0.000 claims description 4
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- 206010061218 Inflammation Diseases 0.000 claims description 3
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 3
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- 239000005418 vegetable material Substances 0.000 claims description 2
- 208000013465 muscle pain Diseases 0.000 claims 1
- 229940096402 milk thistle seed Drugs 0.000 description 15
- 239000000243 solution Substances 0.000 description 10
- 229940079593 drug Drugs 0.000 description 6
- 238000010438 heat treatment Methods 0.000 description 6
- 239000003826 tablet Substances 0.000 description 5
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 description 4
- 239000005662 Paraffin oil Substances 0.000 description 4
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- 239000000843 powder Substances 0.000 description 4
- 229920001817 Agar Polymers 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 239000008272 agar Substances 0.000 description 3
- 230000001707 blastogenic effect Effects 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 210000002966 serum Anatomy 0.000 description 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- 208000000059 Dyspnea Diseases 0.000 description 2
- 206010013975 Dyspnoeas Diseases 0.000 description 2
- 241000233866 Fungi Species 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- PRQROPMIIGLWRP-UHFFFAOYSA-N N-formyl-methionyl-leucyl-phenylalanin Chemical compound CSCCC(NC=O)C(=O)NC(CC(C)C)C(=O)NC(C(O)=O)CC1=CC=CC=C1 PRQROPMIIGLWRP-UHFFFAOYSA-N 0.000 description 2
- 239000012980 RPMI-1640 medium Substances 0.000 description 2
- 238000002835 absorbance Methods 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 244000309466 calf Species 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 229930003935 flavonoid Natural products 0.000 description 2
- 150000002215 flavonoids Chemical class 0.000 description 2
- 235000017173 flavonoids Nutrition 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 206010025135 lupus erythematosus Diseases 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 230000000750 progressive effect Effects 0.000 description 2
- 230000001603 reducing effect Effects 0.000 description 2
- 229920002477 rna polymer Polymers 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 description 2
- 208000008035 Back Pain Diseases 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- 108010052832 Cytochromes Proteins 0.000 description 1
- 102000018832 Cytochromes Human genes 0.000 description 1
- 108010075031 Cytochromes c Proteins 0.000 description 1
- 101100536354 Drosophila melanogaster tant gene Proteins 0.000 description 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- 229920001917 Ficoll Polymers 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 240000005979 Hordeum vulgare Species 0.000 description 1
- 235000007340 Hordeum vulgare Nutrition 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 125000003001 N-formyl-L-methionyl group Chemical group O=C([H])N([H])[C@]([H])(C(=O)[*])C([H])([H])C([H])([H])SC([H])([H])[H] 0.000 description 1
- 108700022034 Opsonin Proteins Proteins 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 235000006089 Phaseolus angularis Nutrition 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 244000000231 Sesamum indicum Species 0.000 description 1
- 235000003434 Sesamum indicum Nutrition 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 244000098338 Triticum aestivum Species 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 240000007098 Vigna angularis Species 0.000 description 1
- 235000010711 Vigna angularis Nutrition 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000000729 antidote Substances 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 229960002537 betamethasone Drugs 0.000 description 1
- 210000000941 bile Anatomy 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 208000034526 bruise Diseases 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
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- 206010009887 colitis Diseases 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000002872 contrast media Substances 0.000 description 1
- YPHMISFOHDHNIV-FSZOTQKASA-N cycloheximide Chemical compound C1[C@@H](C)C[C@H](C)C(=O)[C@@H]1[C@H](O)CC1CC(=O)NC(=O)C1 YPHMISFOHDHNIV-FSZOTQKASA-N 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
- 229910000397 disodium phosphate Inorganic materials 0.000 description 1
- 235000019800 disodium phosphate Nutrition 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- -1 flavonoids Chemical class 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- YFHXZQPUBCBNIP-UHFFFAOYSA-N fura-2 Chemical compound CC1=CC=C(N(CC(O)=O)CC(O)=O)C(OCCOC=2C(=CC=3OC(=CC=3C=2)C=2OC(=CN=2)C(O)=O)N(CC(O)=O)CC(O)=O)=C1 YFHXZQPUBCBNIP-UHFFFAOYSA-N 0.000 description 1
- VPSRLGDRGCKUTK-UHFFFAOYSA-N fura-2-acetoxymethyl ester Chemical compound CC(=O)OCOC(=O)CN(CC(=O)OCOC(C)=O)C1=CC=C(C)C=C1OCCOC(C(=C1)N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)=CC2=C1OC(C=1OC(=CN=1)C(=O)OCOC(C)=O)=C2 VPSRLGDRGCKUTK-UHFFFAOYSA-N 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 229960001680 ibuprofen Drugs 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- MIKKOBKEXMRYFQ-WZTVWXICSA-N meglumine amidotrizoate Chemical compound C[NH2+]C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CC(=O)NC1=C(I)C(NC(C)=O)=C(I)C(C([O-])=O)=C1I MIKKOBKEXMRYFQ-WZTVWXICSA-N 0.000 description 1
- 238000003801 milling Methods 0.000 description 1
- 210000001616 monocyte Anatomy 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 1
- 229910000160 potassium phosphate Inorganic materials 0.000 description 1
- 235000011009 potassium phosphates Nutrition 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 208000005069 pulmonary fibrosis Diseases 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000000552 rheumatic effect Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0004—Homeopathy; Vitalisation; Resonance; Dynamisation, e.g. esoteric applications; Oxygenation of blood
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/065—Microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Medicines Containing Plant Substances (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20420791 | 1991-08-14 | ||
| JP20420791A JP3357383B2 (ja) | 1991-08-14 | 1991-08-14 | 低分子化植物性組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NL9201442A NL9201442A (nl) | 1993-03-01 |
| NL194359B NL194359B (nl) | 2001-10-01 |
| NL194359C true NL194359C (nl) | 2002-02-04 |
Family
ID=16486609
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL9201442A NL194359C (nl) | 1991-08-14 | 1992-08-12 | Werkwijze voor het bereiden van een plantaardige samenstelling met ontstekingsremmende werking. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5531992A (is) |
| JP (1) | JP3357383B2 (is) |
| KR (1) | KR100236454B1 (is) |
| CN (1) | CN1070574A (is) |
| AU (1) | AU660185B2 (is) |
| BE (1) | BE1005641A3 (is) |
| CA (1) | CA2075464A1 (is) |
| CH (1) | CH684781A5 (is) |
| DE (1) | DE4226866A1 (is) |
| DK (1) | DK100492A (is) |
| ES (1) | ES2036496B1 (is) |
| FR (1) | FR2680317B1 (is) |
| GB (1) | GB2258614B (is) |
| HK (1) | HK1006680A1 (is) |
| IS (1) | IS1616B (is) |
| IT (1) | IT1256938B (is) |
| NL (1) | NL194359C (is) |
| NO (1) | NO923160D0 (is) |
| SE (1) | SE9202343D0 (is) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3357383B2 (ja) * | 1991-08-14 | 2002-12-16 | 昌宏 黒田 | 低分子化植物性組成物 |
| JP2955126B2 (ja) * | 1992-06-22 | 1999-10-04 | 笑代 丹羽 | 医薬用油性製剤、食品用油性製剤およびそれらの製造方法 |
| US6379714B1 (en) | 1995-04-14 | 2002-04-30 | Pharmaprint, Inc. | Pharmaceutical grade botanical drugs |
| JP2000159682A (ja) * | 1998-09-17 | 2000-06-13 | Kozo Niwa | 生薬の抗腫瘍活性強化方法、抗腫瘍活性強化生薬含有組成物、生薬処理の抗腫瘍有効性評価方法、および生薬の抗腫瘍有効性評価方法 |
| JP2001199892A (ja) * | 2000-01-17 | 2001-07-24 | Kozo Niwa | アミグダリン含有物の抗腫瘍活性強化方法、抗腫瘍活性強化アミグダリン含有物を含む組成物、アミグダリン含有物処理の抗腫瘍有効性評価方法、およびアミグダリン含有物の抗腫瘍有効性評価方法 |
| US6787164B2 (en) * | 2000-02-23 | 2004-09-07 | Bioselect Innovations, Inc. | Composition and method for treating the effects of diseases and maladies |
| US6841544B2 (en) * | 2000-02-23 | 2005-01-11 | Bioselect Innovations, Inc. | Composition and method for treating the effects of diseases and maladies |
| US7210936B2 (en) * | 2002-07-31 | 2007-05-01 | The Assistant Product Group, Inc. | Multipurpose organizer system and folder with planner and/or writing surface and storage pockets |
| CN100367861C (zh) * | 2004-06-30 | 2008-02-13 | 李宝曌 | 一种面包及其制备方法 |
| CN1315410C (zh) * | 2004-06-30 | 2007-05-16 | 李宝曌 | 一种食用组合物及其制备方法 |
| KR100717891B1 (ko) * | 2004-11-25 | 2007-05-14 | 이지은 | 아토피성 피부염 관련 가려움증 완화 효과를 나타내는 화장료 조성물 |
| US20120114771A1 (en) * | 2009-07-08 | 2012-05-10 | Arkray Inc. | Oxidized Protein Hydrolase Activity Enhancer |
| CN109045286A (zh) * | 2018-08-27 | 2018-12-21 | 微康细胞生命科技(深圳)有限公司 | 一种减小饮酒反应、降低酒精肝损伤的组合物及应用 |
| IT201900017555A1 (it) * | 2019-09-30 | 2021-03-30 | Dymalife Res S R L | Associazione per uso nel trattamento e prevenzione di disturbi infiammatori del tratto intestinale |
| KR102434150B1 (ko) * | 2020-11-25 | 2022-08-19 | 주식회사 네이처센스 | 엉겅퀴 추출물을 유효성분으로 포함하는 이너뷰티용 조성물 |
| KR102568412B1 (ko) * | 2022-05-18 | 2023-08-18 | 한국자연한방 주식회사 | 실리마린 생체이용률이 증대된 밀크씨슬 추출물 제조방법 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2017789A1 (en) * | 1970-04-09 | 1971-10-21 | Klosa, Josef, Dipl.-Chem. Dr.Rer. Nat., 1000 Berlin | Carduus marianus seed extraction and sily-marine isolation |
| GB1383053A (en) * | 1972-03-09 | 1975-02-05 | Inverni Della Beffa Spa | Polyhydroxyphenylchromone derivatives |
| DE2716738A1 (de) * | 1977-04-14 | 1978-10-19 | Josef Dipl Chem Dr Rer N Klosa | Biologisch-pharmazeutisches praeparat |
| DE3537656A1 (de) * | 1984-11-22 | 1986-05-22 | Dr. Madaus GmbH & Co, 5000 Köln | Verfahren zur herstellung von isosilybinfreiem silibinin und arzneimittel, enthaltend silibinin |
| JPS6379834A (ja) * | 1986-09-25 | 1988-04-09 | Kozo Niwa | 活性酸素抑制組成物 |
| JPS6485919A (en) * | 1987-07-17 | 1989-03-30 | Kozo Niwa | Easily absorbable crude drug |
| US5196448A (en) * | 1991-01-22 | 1993-03-23 | Stiefel Laboratories, Inc. | Antiinflammatory compositions and method of use |
| JP3357383B2 (ja) * | 1991-08-14 | 2002-12-16 | 昌宏 黒田 | 低分子化植物性組成物 |
-
1991
- 1991-08-14 JP JP20420791A patent/JP3357383B2/ja not_active Expired - Lifetime
-
1992
- 1992-08-10 DK DK100492A patent/DK100492A/da unknown
- 1992-08-10 CA CA002075464A patent/CA2075464A1/en not_active Abandoned
- 1992-08-11 GB GB9217044A patent/GB2258614B/en not_active Expired - Fee Related
- 1992-08-11 AU AU20972/92A patent/AU660185B2/en not_active Ceased
- 1992-08-12 NL NL9201442A patent/NL194359C/nl not_active IP Right Cessation
- 1992-08-13 CH CH2536/92A patent/CH684781A5/fr not_active IP Right Cessation
- 1992-08-13 DE DE4226866A patent/DE4226866A1/de not_active Withdrawn
- 1992-08-13 KR KR1019920014576A patent/KR100236454B1/ko not_active Expired - Fee Related
- 1992-08-13 NO NO923160A patent/NO923160D0/no unknown
- 1992-08-13 FR FR9210014A patent/FR2680317B1/fr not_active Expired - Fee Related
- 1992-08-13 ES ES9201702A patent/ES2036496B1/es not_active Expired - Fee Related
- 1992-08-13 SE SE9202343A patent/SE9202343D0/xx unknown
- 1992-08-14 CN CN92110462A patent/CN1070574A/zh active Pending
- 1992-08-14 BE BE9200719A patent/BE1005641A3/fr active
- 1992-08-14 IS IS3901A patent/IS1616B/is unknown
- 1992-08-14 IT ITTO920700A patent/IT1256938B/it active IP Right Grant
-
1994
- 1994-06-02 US US08/253,423 patent/US5531992A/en not_active Expired - Fee Related
-
1998
- 1998-06-23 HK HK98106068A patent/HK1006680A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU660185B2 (en) | 1995-06-15 |
| HK1006680A1 (en) | 1999-03-12 |
| ES2036496A1 (es) | 1993-05-16 |
| NL9201442A (nl) | 1993-03-01 |
| GB9217044D0 (en) | 1992-09-23 |
| SE9202343D0 (sv) | 1992-08-13 |
| FR2680317A1 (fr) | 1993-02-19 |
| ITTO920700A1 (it) | 1994-02-14 |
| US5531992A (en) | 1996-07-02 |
| NL194359B (nl) | 2001-10-01 |
| CH684781A5 (fr) | 1994-12-30 |
| AU2097292A (en) | 1993-02-18 |
| DE4226866A1 (de) | 1993-02-18 |
| CN1070574A (zh) | 1993-04-07 |
| ITTO920700A0 (it) | 1992-08-14 |
| IS3901A (is) | 1993-02-15 |
| FR2680317B1 (fr) | 1994-03-25 |
| JP3357383B2 (ja) | 2002-12-16 |
| GB2258614B (en) | 1995-08-09 |
| GB2258614A (en) | 1993-02-17 |
| CA2075464A1 (en) | 1993-02-15 |
| ES2036496B1 (es) | 1993-12-16 |
| IT1256938B (it) | 1995-12-27 |
| KR930003923A (ko) | 1993-03-22 |
| IS1616B (is) | 1996-10-18 |
| BE1005641A3 (fr) | 1993-11-30 |
| DK100492A (da) | 1993-02-15 |
| KR100236454B1 (ko) | 2000-05-01 |
| JPH0543475A (ja) | 1993-02-23 |
| DK100492D0 (da) | 1992-08-10 |
| NO923160D0 (no) | 1992-08-13 |
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