MXPA06004064A - 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis - Google Patents

Abstract

The present invention provides a 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound represented by the following general formula:(1)in the above formula (1), R1 represents a hydrogen atom or C1-C6 alkyl group, n represents an integer of 0 to 6, R1 and -(CH2)nR2 may form a spiro ring represented by the formula (30) below, together with the adjacent carbon atom (in the formula below, RRR represents a piperidyl group which may have substituents on the piperidine ring), (30)and R2 represents a benzothiazolyloxy group, quinolyloxy group, pyridyloxy group or the like. The present compound has an excellent bactericidal actionagainst Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria.

Description

ZW), Eurasian (AM, AZ, BY, KG, KZ, MD, UK, TJ, TM), - before the expiration of the time limit for amending the European (AT, BE, BG, CH, CY, CZ, DE , DK, EE, ES, H, claims and to be rep blished in the event of receipt of FR, GB, GR, HU, DB, 1T, LU, MC, NL, PL, PT, RO, SE, SI, amendments SK, TR), OAPI (BF, BJ, CF, CG, Cl, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). For two-letter codes and other abbreviations, referto the "Guid¬ Published: ance Notes on Codes and Abbreviations "appearing at ihe begin- COMPOUNDS OF 2, 3-DIHYDRO-6-NITROIMIDAZO [2, 1-B] OXAZOLE FOR THE TREATMENT OF TUBERCULOSIS Field of the Invention The present invention relates to a 2,3-dihydroimidazo [2, 1-b] oxazole compound. Background of the Invention Among the acid-fast bacteria, human Mycobacterium tuberculosis is widely known. It is said that one third of the human population is ionfected with this bacteria. In addition to human Mycobacterium tuberculosis, Mycobacterium africanum and Mycobacterium bovis are also known to belong to the Mycobacterium tuberoculosis group. These bacteria are known as Mycobacteria that have a strong pathogenicity to humans. Against these tuberculosis patients, the treatment is carried out using three agents, rifampin, isoniazid, and ethambutol (or streptomycin) which are seen as first-line agents, or using four agents such as the three above agents and pyrazinamide. However, since treatment of tuberculosis requires administration of agents of extremely long duration, it can result in poor compliance, and treatment often ends up failing. On the other hand, with respect to the previous agents, it has been reported that: rifampicin causes liver disease, Ref.- 170235 flu syndrome, allergy to the drug, and its concomitant administration with other drugs is contraindicated due to the induction of the enzyme associated with P450; that isoniazid causes peripheral nervous system disorder and induces serious hepatopathy when used in combination with rifampicin; that ethambutol leads to the failure of the sense and scope of sight due to optic nerve disorder; that streptomycin is linked to the decrease of the faculty of the ear due to the disorder of the 8th cranial nerve; and that pyrazinamide causes adverse reactions such as liver disease, gout attack associated with increased uric acid level, vomiting (A Clinician's Guide to Tuberculosis, Michael D. Iseman 2000 by Lippincott Williams &Wilkins, printed in the USA, ISBN 0-7817-1749-3, Tuberculosis, 2nd edition, Fumiyuki Kuze and Takahide Izumi, Igaku-Shoin Ltd., 1992). Currently, it has been reported that cases where standard chemotherapy can not be carried out due to adverse reactions to these agents make up to 70% (approximately 23%, 52 cases) of the total cases where the administration of the agents is discontinued (the 228 total hospitalized patients who undergo the investigation) (Kekkaku, Vol. 74, 77-82, 1999). In particular, the hepatotoxicity, which is induced by rifampicin, isoniazid, and ethambutol of the 5 agents used in combination for the aforementioned first line treatment, is known as an adverse reaction that develops more frequently. At the same time, Mycobacterium tuberculosis resistant to antitubercular agents, Mycobacterium tuberculosis resistant to multiple drugs, and the like have increased, and the presence of these types of Mycobacterium tuberculosis makes the treatment more difficult. In accordance with the research done by WHO (1996 to 1999), the proportion of Mycobacterium tuberculosis that is resistant to any of the existing antitubercular agents up to the total of Mycobacterium tuberculosis types that have been isolated in the world reaches 19%, and It has been reported that the proportion of Mycobacterium tuberculosis resistant to multiple drugs is 5.1%. The number of carriers infected with such Mycobacterium tuberculosis resistant to multiple drugs is estimated to be 60, 000,000, and there is a lot of concern that Mycobacterium tuberculosis that is resistant to multiple drugs will increase in the future (April 2001 as a supplement to the Tuberculosis newspaper, the "Scientific Blueprint for TB Drug Development"). In addition, the major cause of death of patients with AIDS is tuberculosis. It has been reported that the number of humans suffering from both tuberculosis and HIV reaches 10,700,000 a year 1997 (Global Alliance for TB drug development). On the other hand, it is considered that the mixed infection of tuberculosis and HIV has at least 30 times a higher risk of developing tuberculosis than ordinary circumstances. Taking into consideration the aforementioned current situation, the profiles of the desired antitubercular agent are as follows: (1) an agent, which is still effective for Mycobacterium tuberculosis resistant to multiple drugs, (2) an agent that allows short-term chemotherapy, (3) an agent with some adverse reactions, (4) an agent that shows efficacy for a latent infection of Mycobacterium tuberculosis (ie, latent Mycobacterium tuberculosis), and (5) an orally administrable agent. Examples of bacteria known to have a pathogenicity to humans include bacteria aggressors of the recently increased MAC infection (avium-intracellular complex infection) such as Mycobacterium avium and Mycobacterium intracellulare, and atypical acid fasting bacterium such as Mycobacterium kansasii, Mycobacterium marinum, Mycobacterium si iae, Mycobacterium scrofulaceum, Mycobacterium szulgai, Mycobacterium xenopi, Mycobacterium malmoense, Mycobacterium haemophilum, Mycobacterium ulcerans, Mycobacterium shimoidei, Mycobacterium fortuitum, Mycobacterium chelonae, Mycobacterium smegmatis, and Mycobacterium aurum. These days, there are some effective therapeutic agents for these atypical fasting bacterium infections. Under the present circumstances, antitubercular agents such as rifampicin, isoniazid, ethambutol, streptomycin and kanamycin, a novel quinoline agent which is a therapeutic agent for common bacterial infections, macrolide antibiotics, aminoglycoside antibiotics, and tetracycline antibiotics are used in combination. However, when compared to the treatment of common bacterial infections, the treatment of atypical fasting bacterial infections requires a long-term administration of agents, and cases have been reported where the infection is changed to an intractable one, eventually leading to death. To break the aforementioned current situation, the development of an agent having a stronger efficacy is desired. For example, the International Patent Application International Publication No. 11-508270 (WO97 / 01562) discloses that a compound of 6-nitro-1,2,3,4-tetrahydro [2, 1-b] -imidazopyran has a bactericidal action in vitro for Mycobacterium tuberculosis (strain H37Rv) and Mycobacterium tuberculosis resistant to multiple drugs, and that the above compound has a therapeutic effect for a model of animal infected with tuberculosis when administered orally and thus is useful as an antitubercular agent. However, the compound described in the above publication differs from the compound of the present invention in terms of the basic structure, and is considered to be a compound not similar to the inventive compound. Kuppsuwamy Nagarajan et al. has reported in European Journal of Medicinal Chemistry, 1989, Vol. 24, pp.631-633 that the compounds represented by the following general formula (I): wherein R1 represents a hydrogen atom or methyl group and - (CH2) nR2 represent a chloromethyl group, C1-C7 alkyl group, isopropoxymethyl group, 3-propenyloxy-methyl group, or unsubstituted phenoxymethyl group, and compounds represented by the same general formula above (I), wherein R1 and - (CH2) nR2 link each to form a ring cyclopentane or cyclohexane (16 types of compounds in total) have a bactericidal action for Mycobacterium tuberculosis (strain H37Rv). However, the above publication discloses that only the 4 types of compounds of the above compounds are effective when administered orally. It is also disclosed that the compound having the highest activity, that is, the compound (CGI-17341) represented by the above general formula (I) wherein R 1 represents a hydrogen atom and - (CH 2) nR 2 represents ethyl, found that it has mutagenicity, and consequently, the development of these series of compounds as agents was abandoned. In addition, Dilip R. Astekar et al. have reported on Antimicrobial Agents and Chemotherapy, Feb. 1993, pp. 183-186 about the antimicrobial profile of the previous compound CGI-17341. According to the report, the compound CGI-17341 has a bactericidal action for Mycobacterium tuberculosis (strain H37Rv) and Mycobacterium tuberculosis resistant to multiple drugs, but it does not have the activity for the atypical acid fasting bacterium, M ^ avium, M. intracellulare, and 1ML_ fortuitum when used at 250 μg / ml or less. On the other hand, Journal of Medicinal Chemistry, 1981, Vol. 24, pp. 601-604 discloses that the 6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole compounds have a radiosensitizing capacity for hypoxic mammalian cells. Detailed Description of the Invention It is an object of the present invention to provide a compound having an excellent bactericidal action for Mycobacterium tuberculosis and Mycobacterium tuberculosis resistant to multiple drugs. It is another object of the present invention to provide a compound that has an excellent bactericidal action for the fasting bacterium atypical acid. As a result of intense studies, the present inventors have succeeded in synthesizing a novel 2,3-dihydroimidazo [2, 1-b] oxazole compound, which has an excellent bactericidal action for Mycobacterium tuberculosis, Mycobacterium tuberculosis resistant to multiple drugs , and atypical acid fasting bacteria. The present invention has been completed based on such findings. The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound represented by the following general formula (1), optically active form thereof, or pharmaceutically acceptable salt thereof: wherein R1 represents a hydrogen atom or a Cl-6 alkyl group, n represents an integer between 0 and 6, R1 and - (CH) nR2 can be linked to each other together with carbon atoms adjacent thereto, for this way to form a spiro ring represented by the general formula (30): oo; wherein RRR represents a piperidyl group [wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, may be substituted)], and R2 represents a group described in any of the following (a) to (y): ( a) a phenyl group (wherein, in the phenyl ring, at least one piperidyl group can be substituted [wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]); (b) a benzothiazolyloxy group (wherein, in the benzothiazole ring, at least one selected from the group consisting of the following (b-1) through (b-5) can be substituted: (b-1) a phenyl group [ wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can to be substituted], (b-2) a piperazinyl group [wherein, in the piperazine ring, at least one selected from the group consisting of a C1-C6 alkyl group phenyl (wherein, in the phenyl group, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a C2-C6 alkenyl group phenyl (wherein, in the phenyl group, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), and a phenyl group (wherein, in the phenyl group, less one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), can be substituted], (b-3) a piperidyl group [wherein, in the piperidine ring, at least one selected from the group consisting of an amino group (wherein, in the amino group, at least one selected from the group consisting of a phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be replaced] and a group at C1-C6 quilo can be substituted), a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), and a C1-C6 alkyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a group C1-C6 alkyl substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a pyrrolyl group [, where in the ring, can be substituted], (b-4) pyrrole, at least one selected from the group consisting of a C1-C6 alkyl group and a C1-C6 alkyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a group C1-C6 alkyl substituted or unsubstituted with halogen, and an alkali group C1-C6 oxy substituted or unsubstituted with halogen, can be substituted), and (b-5) a phenylthio group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen, a C 1 -C 6 alkyl group substituted or unsubstituted by halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted by halogen, can be substituted)); (c) a quinolyloxy group (wherein, in the quinoline ring, at least one selected from the group consisting of the following (c-1) to (c-4) can be substituted: (c-1) a halogen atom , (c-2) a phenoxy group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and an alkoxy C1 group -C6 substituted or unsubstituted with halogen, can be substituted], (c-3) a piperazinyl group [wherein, in the piperazine ring, at least one selected from the group consisting of a C1-C6 alkyl group phenyl (in where, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C1-C6 alkyl group with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a phenyl group [wherein, on the phenyl ring, at least one group selected from the group consists of a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a substituted C1-C6 alkoxy group or not substituted by halogen, can be substituted), a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-C6 alkoxy group substituted or unsubstituted by halogen, can be substituted], and a group C2-C6 alkenyl phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted C1-C6 alkoxy group or not substituted by halogen, can be substituted], and can be substituted], and (c-4) a piperidyl group [wherein, in the piperidine ring, at least one selected from the following group can be substituted: an amino group (wherein , in the amino group, at least one selected from the group consisting of a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and an alkoxy group C1 -C6 substituted or unsubstituted with halogen, can be substituted] and a C1-C6 alkyl group can be substituted); a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C 1 -C 6 alkyl group, and a substituted or unsubstituted C 1 -C 6 alkoxy group with halogen, it can be replaced); a C 1 -C 6 alkyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a C 1 -C 4 alkylenedioxy group, a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted); a C 1 -C 6 alkoxy phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or not substituted with halogen, can be substituted); a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, it can be replaced); a C 1 -C 6 alkyl naphthyl group; and a C1-C6 alkylidene group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-6 alkoxy group C6 substituted or unsubstituted with halogen, can be replaced)]); (d) a pyridyloxy group (wherein, in the pyridine ring, at least one selected from the group consisting of the following (d-1) and (d-2) can be substituted: (d-1) a piperidyl group [ where, in the piperidine ring, at least one selected from the group consisting of a phenoxy group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or not substituted with halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a C 1 -C 6 alkyl group substituted with C 1 -C 6 alkoxy phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a C1-C6 alkyl phenoxy group (in wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be replaced), and a group C 1 -C 6 alkyl phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted by halogen, and a substituted C 1 -C 6 alkoxy group or not replaced with halogen, can be replaced), can be replaced]; and d-2) a piperazinyl group [wherein, in the piperazine ring, at least one selected from the group consisting of a C 1 -C 6 alkoxycarbonyl group, a C 1 -C 6 alkyl furyl group [wherein, in the furan ring, at least one phenyl group can be substituted (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-6 alkoxy group C6 substituted or unsubstituted with halogen, can be substituted)], a C1-C6 alkyl pyridyl group [wherein, in the pyridine ring, at least one selected from the group consisting of a furyl group and a phenyl group can be substituted ( wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can to be substituted)], a C1-C6 alkyl group benzothienyl (wherein, in the benzothiophene ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen , may be substituted), a C2-C6 alkenyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a C 1 -C 6 alkyl benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a group C 1 -C 6 alkyl substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen, can be substituted], a C 2 -C 6 alkenyl benzofuryl group [wherein, in the benzofuran ring, at least one selected of the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], a C1-C6 alkyl thiazolyl group [in where, in the thiazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen , and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)], a C1-C6 alkyl phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom , a C 1 -C 6 alkyl group substituted or not substituted by halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted by halogen, can be substituted), a C 1 -C 6 alkyl indolyl group (wherein, in the indole ring, minus one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), and a C1-C6 alkyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a benzofuryl group, a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be replaced) can be replaced]); (e) a 1, 2, 3, 4-tetrahydroquinolyoxy group (wherein, in the 1, 2, 3, 4-tetrahydroquinoline ring, at least one selected from the group consisting of an oxo group, a phenyl group [wherein , in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted ], and a C1-C6 alkyl group phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and an alkoxy group C1-C6 substituted or not substituted with halogen, can be replaced], can be replaced); (f) a 1, 2, 3, 4-tetrahydronaphthyloxy group (wherein, in the 1, 2, 3, 4-tetrahydronaphthalene ring, at least one oxo group can be substituted); (g) a 2H-chromenoxide group (wherein, in the 2H-chromene ring, at least one oxo group can be substituted); (h) a naphthyloxy group (wherein, in the naphthalene ring, at least one piperidyl group can be substituted [wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C1-C6 alkyl group) with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]); (i) a 1,2,3,4-tetrahydroisoquinolyoxy group (wherein, in the 1, 2, 3, 4-tetrahydroisoquinoline ring, at least one selected from the group consisting of a C1-C6 alkoxycarbonyl group, an alkyl group C1-C6 phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be substituted], and a phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], can be substituted); (j) a group -NR22R23 (wherein R22 represents a hydrogen atom or a C1-C6 alkyl group, and R23 represents at least one selected from the following (j-1) to (j-5): (j-1) ) a phenyl group [wherein, in the phenyl ring, at least one piperidyl group is substituted (wherein, in the piperidine ring, at least one phenoxy group can be substituted [wherein, in the phenyl ring, at least one selected of the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted])], (j-2) a C 1 -C 6 alkyl group phenyl [wherein, in the phenyl ring, at least one group selected from the group consisting of a piperidyl group (wherein, in the piperidine ring, a phenoxy group is substituted [wherein, in the phenyl ring , at least one selected from the group consisting of a halogen atom, a substituted C1-C6 alkyl group or not halogen-substituted, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted]) and a group -NR24R25 (wherein R24 represents a hydrogen atom or C1-C6 alkyl group, and R25 represents an alkenyl group C2-C6 phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, it can be substituted]), substituted], (j-3) a C1-C6 alkyl piperidyl group [wherein, in the piperidine ring, at least one phenyl group is substituted (wherein, in the phenyl ring , at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)], (j -4) a thiazolyl group [where, in the thiazole ring, at least one group selected from the group consisting of a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a C1-C6 alkyl piperazinyl group (wherein, in the piperazine ring, at least one phenyl group can be substituted [wherein, in the ring phenyl, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted]), and a C1-C6 alkyl piperidyl group (wherein, in the piperidine ring, at least one phenoxy group can be substituted [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted]), can be substituted], and (j-5) a C2- alkenyl group C6 phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be replaced)); (k) a benzoxazolyloxy group (wherein, in the benzoxazole ring, at least one selected from the group consisting of a piperazinyl group [wherein, in the piperazine ring, at least one selected from the group consisting of an alkyl group C1 -C6 phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, can be substituted), and a C2-C6 alkenyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a piperidyl group can be substituted (wherein, in the piperidine ring, at least one selected from the group consisting of an alkyl group C1-C6 phenyl [in don of, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted] and an amino group [wherein, in the amino group, at least one selected from the group consisting of a C1-C6 alkyl group and a phenyl group (wherein, in the phenyl ring, at least one selected from the group consists of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted) can be substituted] can be substituted), and a group phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen , can be replaced], can be replaced); (1) a benzoimidazolyloxy group (wherein, in the benzoimidazole ring, at least one selected from the group consisting of a C1-C6 alkyl group, a phenyl group [wherein, in the phenyl ring, at least one selected from the group consists of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], a piperidyl group [where, in the piperidine ring , at least one phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a substituted C1-C6 alkoxy group or not substituted by halogen can be substituted), a piperazinyl group [wherein, in the piperazine ring, at least one C1-C6 alkyl group phenyl (wherein, on the phenyl ring, at least one selected from the group which consists of an atom of h alkoxy, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] and a C1-C6 alkyl group phenyl [wherein, in the ring phenyl, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], can be replaced); (m) a 1, 2, 3, 4-tetrahydroisoquinolyl group (wherein, in the 1, 2, 3, 4-tetrahydroisoquinoline ring, at least one selected from the group consisting of the following (ml) and (m-2) ) can be substituted: (ml) an amino group [wherein, in the amino group, at least one selected from the group consisting of a C1-C6 alkyl group, a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), and a C1-C6 alkyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom , a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), and can be substituted] and (m-2) a phenoxy group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted] ); (n) a piperidyl group (wherein, in the piperidine ring, at least one selected from the group consisting of the following (n-1) to (n-4) can be substituted: (n-1) a phenyl group [ wherein, on the phenyl ring, at least one group -NR26R27 is substituted (wherein R26 represents a hydrogen atom or C1-C6 alkyl group, and R27 represents a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted])], (n-2) a group -W? NR28R29 [wherein Wi represents a C1-C6 alkylene group, R28 represents a hydrogen atom or C1-C6 alkyl group, and R29 represents a phenyl group (wherein, on the phenyl ring, at least one selected of the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy substituted or unsubstituted by halogen can be substituted)], (n-3) a C 1 -C 6 alkoxy group in which two phenyl groups are substituted [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], and (n-4) an alkyl group C1-C6 phenyl [wherein, in the phenyl group ring, at least one phenyl group is substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-alkyl group C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]); (o) a piperazinyl group (wherein, in the piperazine ring, at least one selected from the following group is substituted: a C1-C6 alkyl group in which two phenyl groups are substituted [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], a C1-C6 alkyl group phenyl [wherein, in the phenyl ring, at least one phenoxy group is substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C1-C6 alkyl group) with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, is substituted)], a thiazolyl group (wherein, in the thiazole ring, at least one phenyl group can be substituted), a C1-C6 alkyl group phenoxy (where, in the phenyl ring or, at least one selected from the group consisting of a phenyl group (wherein, on the phenyl ring, halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be substituted), a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a C 2 alkenyl group -C6 phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, is substituted], and an imidazolyl group [wherein, in the imidazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom , a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]); (p) a thiazolyl C1-C6 alkoxy group (wherein, in the thiazole ring, at least one type selected from the group consisting of the following (p-1) to (p-5) can be substituted: (p-1) ) a C1-C6 alkyl phenoxy group [where, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted ], (p-2) an anilino C1-C6 alkyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted by halogen, can be substituted], (p-3) a C1-C6 alkyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], (p-4) a C1-C6 alkyl piperazinyl group [wherein, in the piperazine ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of one atom of halogen, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-C6 alkoxy group substituted or unsubstituted by halogen, can be substituted), and (p-5) a C1-C6 alkyl piperidyl group [ wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C 1 -C 6 alkyl group) halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]); (q) an 8-azabicyclo [3.2.1] octyl group (wherein, in the 8-azabicyclo [3, 2, 1] octane ring, at least one phenoxy group can be substituted [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted]); (r) a group represented by the following chemical formula (31): [wherein X represents a halogen atom, or a C 1 -C 6 alkyl group substituted with amino which can have a C 1 -C 6 alkyl group as a substituent, m represents an integer between 0 and 3, and R 3 represents a group described in any of the following (i) through (xxii): (i) a group - (W) or -NR4R5 (wherein W represents a group -CO- or a C1-C6 alkylene group, or represents 0 or 1, R4 represents a hydrogen atom, a C1-C6 alkyl group, or a phenylcarbamoyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], and R5 represents: a C1-C6 alkoxycarbonyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of one atom of halogen, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-6 alkoxy group C6 substituted or unsubstituted with halogen, can be replaced]; a C2-C6 alkenylcarbonyl phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be replaced]; a C2-C6 alkenyl phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be replaced]; a C1-C6 alkyl piperidyl group [wherein, in the piperidine ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]; a C1-C6 alkyl group phenyl (wherein, on the phenyl ring, at least one phenyl group is substituted (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1 -C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)); a C 1 -C 6 alkyl benzofuryl group (wherein, in the benzofuran ring, at least one C 1 -C 6 alkyl group substituted or unsubstituted with halogen can be substituted); a C1-C6 alkyl group piperidinylcarbonyl [wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted); or a group represented by the following chemical formula (32): wherein R6 represents: a C1-C6 alkyl group; a phenyl group (wherein, on the phenyl ring, at least one selected from the following group can be substituted: a C 1 -C 4 alkylenedioxy group, a cyano group, a nitro group, an amino group which can have a C 1 -C 6 alkyl group as a substituent, an amino-substituted sulfonyl group which may have a C1-C6 alkyl group as a substituent, a C1-C6 alkoxycarbonyl group, a C1-C6 alkylthio group, a phenoxy group, a C1-C6 alkoxy phenyl group, a pyrrolidinyl group [wherein, in the pyrrolidine ring, at least one oxo group can be substituted], an imidazolyl group, an isoxazolyl group, an oxazolyl group, a C1-C6 alkyl group phenyl, a phenyl group, a C1-6 alkyl group C6 amino which may have a C1-C6 alkyl group as a substituent, a C1-C6 alkoxy pyrrolidinyl group, a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted C1-C6 alkoxy group or not substituted with halogen); a C 1 -C 6 alkoxycarbonyl phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted by halogen, and a C 1 -C 6 alkoxy group substituted or not substituted with halogen, can be substituted); a C 1 -C 6 alkyl benzofuryl group (wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or not substituted with halogen, can be substituted); a C2-C6 alkenyl benzofuryl group (wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be substituted); a C1-C6 alkyl phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be substituted); a C 1 -C 6 alkyl thiazolyl group (wherein, in the thiazole ring, at least one phenyl group can be substituted [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted]); a C 1 -C 6 alkyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a phenyl group (wherein, on the phenyl ring, a halogen atom, a substituted C 1 -C 6 alkyl group or not substituted by halogen, and a C1-C6 alkoxy group substituted or unsubstituted by halogen, can be substituted), a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a substituted C1-C6 alkoxy group or not substituted with halogen, can be substituted]; a C 1 -C 6 alkyl pyridyl group [wherein, in the pyridine ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]; a C1-C6 alkoxycarbonyl group; a benzoyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C 1 -C 6 alkyl group, and a substituted or unsubstituted C 1 -C 6 alkoxy group with halogen, it can be replaced); a phenylcarbamoyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, can be replaced); a C 1 -C 6 alkyl benzothienyl group (wherein, in the benzothiophene ring, at least one halogen atom can be substituted); an alkyl Cl-Cß indolyl group (wherein, in the indole ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be substituted); a 4H-1, 3-benzodioxinyl group (wherein, in the 4H-1, 3-benzodioxine ring, at least one halogen atom can be substituted); benzothienyl group; a naphthyl group; a quinolyl group; a benzothiazolyl group (wherein, in the benzothiazole ring, at least one C1-C6 alkyl group can be substituted); a 2, 3-dihydro-lH-indenyl group (wherein, in the 2, 3-dihydro-lH-indan ring, at least one oxo group can be substituted); or a 9H-fluorenyl group or C2-C6 alkenyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted)); (ii) a group represented by the following chemical formula (33): (where W and I are the same as above, a dotted line represents that the link can be a double bond, and when the dotted line represents a double bond, this means that only R8 is substituted, R7 represents a hydrogen atom, group hydroxyl, C1-C6 alkoxy group, or phenyl group [wherein, in the phenyl ring, halogen can be substituted]; and R8 represents a group described in any of the following (1) to (63): (1) a group C 1 -C 6 alkyl substituted with C 1 -C 6 alkoxy phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a C 1 -C 4 alkylenedioxy group, a halogen atom, a cyano group, a phenyl group, a C1-C6 alkoxy group phenyl, a C2-C6 alkenyl group phenyl, a phenoxy group, a C1-C6 alkylthio group, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, it can be substituted), (2) a C 1 -C 6 alkoxy phenyl group ( wherein, in the phenyl ring, at least one selected from the group consisting of a cyano group, a phenyl group, a C1-C6 alkoxycarbonyl group, a phenoxy group, a C1-C6 alkylthio group, a halogen atom, a group C 1 -C 6 alkyl substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen, can be substituted); (3) a C2-C6 alkenyloxy phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and an alkoxy group C1-C6 substituted or unsubstituted with halogen, can be substituted); (4) a group - (W) or -NR9R10 (where W and I are the same as above, and R9 and R10 each identically or differently represent: a hydrogen atom; a C1-C6 alkyl group which may have a group hydroxyl as a substituent, a C1-C6 alkanoyl group, a C1-C6 alkoxycarbonyl group, a C1-C6 alkoxycarbonyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted by halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted by halogen, can be substituted]; a phenyl group [in the phenyl ring, at least one selected from the following group can be substituted as a substituent: a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, a C1-C6 alkoxy group substituted or unsubstituted by halogen, an amino group which may have, as a substituent, a group selected from the group consisting of group consisting of a g C1-C6 alkanoyl group and a C1-C6 alkyl group, a C1-C6 alkoxycarbonyl group, a phenyl group, a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted by halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted by halogen, can be substituted), an aminosulfonyl group, a 1, 2, 3, 4-tetrahydroquinolyl group (wherein , in ring 1, 2, 3, 4-tetrahydroquinoline, at least one oxo group can be substituted as a substituent), a C1-C6 alkylsulfonyl group, a C3-C8 cycloalkyl group, a nitro group, a cyano group, a C1-C6 alkylthio group, a phenylsulfonyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C1-alkoxy group -C6 substituted or unsubstituted with halogen, can be substituted), an alkyl C group 1-C6 substituted with hydroxyl group, and a group represented by the following chemical formula (34): (wherein i represents a C1-C6 alkylene group, and R11 and R12 each identically or differently represent a C1-C6 alkoxy group)]; a C 1 -C 6 alkyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a C 1 -C 4 alkylenedioxy group, a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be substituted), a group -N (R11A) R12A (wherein R11A and R1 A each identically or differently represent a hydrogen atom, C1-C6 alkyl group, or phenyl group, and R11A and R12A can bond to each other together with nitrogen atoms adjacent to it directly or through nitrogen, oxygen or sulfur atoms, so that they form a 5-7 membered saturated heterocyclic ring), a phenoxy group (where, on the phenyl ring , at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), an alkoxy group Cl-Cβ phenyl, a Cl-Cß alkoxy group substituted with amino group which may have a Cl-Cβ alkyl group as a substituent, a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a substituted C 1 -C 10 alkoxy group or not substituted with halogen, can be replaced as a substituent]; an alkyl Cl-Cβ benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or not substituted with halogen, can be replaced]; an f-phenylsulfonyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted by halogen, and a C1-Cß substituted alkoxy group or not substituted with halogen, and a C1-C4 alkylenedioxy can be substituted]; a f-enoxycarbonyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be replaced]; a C2-C6 alkenyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C3 alkyl group substituted or unsubstituted by halogen, and a C1-C [beta] alkoxy group substituted or not substituted with halogen, can be replaced]; a C1-C6 alkyl group substituted with C1-C6 alkoxy; a C2-C6 alkenyl group; a C2-C6 alkanoyl group substituted with C1-C6 alkoxy; a C1-C6 alkyl group substituted with C3-C8 cycloalkyl; a C 1 -C 6 alkyl phenoxy group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or not substituted with halogen, can be replaced]; a benzoyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen, and a substituted or unsubstituted Cl-Cβ alkoxy group with halogen, it can be replaced]; an enylcarbamoyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or not substituted with halogen, can be replaced]; a pyridyl group; an alkyl Cl-Cβ pyridyl group; a C1-C6 alkyl imdazolyl group; a 1, 2, 3, 4-tetrahydroquinolyl group [wherein, in the 1,2,3,4-tetrahydroquinoline ring, at least one selected from the group consisting of an oxo group and a Cl-Cß alkyl group can be substituted as a substituent]; a quinolyl group; an indolyl group; an amino group which may have a Cl-Cß alkyl group as a substituent; an indazolyl group; a naphthyl group; a C3-C8 cycloalkyl group; a C 1 -C 6 alkyl group substituted with amino which may have a Cl-Cß alkyl group as a substituent; a Cl-Cß alkyl group substituted with cyano; a C 1 -C 3 alkyl group substituted with furyl; a group of the formula (35) (wherein RR represents a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-6 alkoxy group) C6 substituted or unsubstituted with halogen, can be substituted)); or a C1-C6 alkyl group substituted with piperazinyl [wherein, in the piperazine ring, at least one phenyl group can be substituted as a substituent (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)], in addition, R9 and R10 can be linked together with atoms of nitrogen adjacent to it directly or through nitrogen, oxygen or sulfur atoms, so that they form a 1,2,3,4-tetrahydroisoquinolyl group, isoindolyl group, or 5-7 membered saturated heterocyclic ring, wherein, in the heterocyclic ring, at least one selected from the following group can be substituted: a halogen atom, a substituted or unsubstituted C 1 -C 6 alkyl group with halogen, a substituted or unsubstituted C 1 -C 6 alkoxy group with halogen, a g phenyl ring [wherein, in the phenyl ring, at least one selected from the group consisting of a phenyl group, a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted C1-C6 alkoxy group or not substituted by halogen, can be substituted], a benzoyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], a C1-C6 alkyl group pyridyl, a C3-C8 cycloalkyl group, a C1-C6 alkyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a C1-C4 alkylenedioxy group, a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], a C1-C6 alkyl group pipe ridyl, a piperidyl group, a C1-C6 alkoxy phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted by halogen, can be substituted], a phenoxy group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted], an amino group wherein at least one selected from the group consisting of a phenyl group [wherein, in the ring phenyl, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, may be substituted], a group C1-C6 alkyl, and a C1-C6 alkyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, - and a C1-6 alkoxy group C6 substituted or unsubstituted with halogen, can be substituted], can be substituted as a substituent, a benzoxazolyl group, a C2-C6 alkenyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), and a benzoimidazolyl group); (5) an alkyl Cl-Cβ phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or not substituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), a Cl-Cß alkyl group substituted or not substituted by halogen, and a Cl-Cß alkoxy group substituted or unsubstituted with halogen, can be replaced); (6) a carbamoyloxy group (wherein, in the amino group, at least one selected from the group consisting of a Cl-Cß alkyl group and a phenyl group [wherein, in the phenyl ring, at least one selected from the group consists of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted] can be substituted); (7) a C 1 -C 6 alkyl group substituted with carbamoyloxy (wherein, in the amino group, at least one selected from the group consisting of a C 1 -C 6 alkyl group, a Cl-C 3 alkyl phenyl group, a C 3 cycloalkyl group C8, a naphthyl group, a 2,3-dihydro-lH-indenyl group, a 2,3-dihydrobenzofuryl group, and a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of one group C1-C4 alkylenedioxy, a cyano group, a phenoxy group, a C1-C6 alkylthio group, a C1-C6 alkanoyl group, a phenyl group, a C1-C6 alkyl group phenyl, a halogen atom, a C1-C10 alkyl group substituted or unsubstituted with halogen, and a C1-C10 alkoxy group substituted or unsubstituted with halogen, can be substituted], can be substituted); (8) a Cl-Cβ phenoxy alkyl group (wherein, at the phenyl ring, at least one selected from the following group can be substituted: a halogen atom, a C 1 -C 4 alkylenedioxy group, a C 1 -C 4 alkoxycarbonyl group; phenyl group, a phenoxy group, a pyrrolyl group, a benzothiazolyl group, a 1,2,4-triazolyl group, an imidazolyl group, an isoxazolyl group, a benzoxazolyl group, a benzotriazolyl group, a cyano group, a nitro group, a C2-C6 alkenyl group, a C1-C6 alkanoyl group, a C1-C6 alkyl group substituted with C1-C6 alkoxycarbonyl, a C1-C6 alkyl group substituted with C1-C14 alkanoyl, a group -N (R11B) R12B (wherein RllB and R12B each identically or differently represent a hydrogen atom, Cl-Cß alkyl group, Cl-Cß alkanoyl group, or phenyl group, and R11B and R12B can be linked together with nitrogen atoms adjacent thereto directly or through of nitrogen, oxygen or sulfur atoms, so that it forms n a saturated 5-7 membered heterocyclic ring, wherein, in the heterocyclic ring, at least one selected from the group consisting of a Cl-Cβ alkoxycarbonyl group and an amino group [wherein, in the amino group, at least one selected from a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted C1-C6 alkoxy group or not substituted with halogen, can be substituted) and a C 1 -C 6 alkyl group can be substituted] can be substituted); a C 1 -C 6 alkoxy phenyl group; a C1-C6 alkyl group phenyl; an alkylthio Cl-Cß group; a C3-C8 cycloalkyl group; a C1-C6 alkyl group substituted or unsubstituted with halogen; and a C1-C10 alkoxy group substituted or unsubstituted with halogen); (9) a C 1 -C 6 alkyl tetrahydropyranyloxy group; (10) a C 1 -C 6 alkyl group substituted with hydroxyl; (11) a C 1 -C 6 alkyl group substituted with Cl-Cβ alkoxy furyl (wherein, in the furan ring, at least one Cl-Cβ alkoxycarbonyl group can be substituted); (12) a Cl-Cß alkyl group substituted with Cl-C6 alkoxy tetrazolyl (wherein, in the tetrazole ring, at least one selected from the group consisting of a phenyl group (wherein, in the phenyl ring, at least one selected of the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), a Cl-Cβ phenyl alkyl group, and a C3-C8 cycloalkyl C1-C3 alkyl group, can be substituted); (13) a Cl-Cß alkyl group substituted with Cl-Cβ isoxazolyl alkoxy (wherein, in the isoxazole ring, at least one Cl-Cß alkyl group can be substituted); (14) a Cl-Cß alkyl group substituted with Cl-Cβ benzothienyl alkoxy (wherein, in the benzothiophene ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted); (15) a Cl-Cß alkyl group substituted with Cl-Cβ 1, 3, 4-oxadiazolyl alkoxy (wherein, in ring 1, 3, 4-oxadiazole, a phenyl group can be substituted [wherein, in the ring phenyl, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted]); (16) a C1-C6 alkyl group substituted with C2-C6 alkynyloxy; (17) a C1-C6 alkyl group substituted with C1-C6 alkoxy naphthyl; (18) a C1-C6 alkyl group substituted with C1-C6 alkoxy, 2,4-oxadiazolyl [wherein, in the 1,2,4-oxadiazole ring, a phenyl group can be substituted]; (19) a Cl-Cß alkyl group substituted with Cl-Cβ pyridyl alkoxy [wherein, in the pyridine ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted]; (20) a Cl-Cß alkyl group substituted with Cl-Cβ thiazolyl alkoxy [wherein, in the thiazole ring, at least one selected from the group consisting of a phenyl group (wherein, in the phenyl ring, at least one selected of the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted) and a Cl-Cß alkyl group can be substituted. replaced]; (21) a C1-C6 alkyl group substituted with 1, 2, 3, 4-tetrahydronaphthyl Cl-C 1 alkoxy [wherein, in the 1,2,3,4-tetrahydronaphthalene ring, at least one C 1 -C 6 alkyl group can be to be replaced]; (22) a C 1 -C 6 alkyl group substituted with C 1 -C 6 alkoxy carbamoyl [wherein, in the amino group, at least one selected from the group consisting of a C 3 -C 8 cycloalkyl group and a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted) can be replaced]; (23) a Cl-Cß alkyl group substituted with Cl-Cβ-benzofuryl alkoxy [wherein, in the benzofuran ring, at least one cyano group can be substituted]; (24) a Cl-Cβ benzofuryl alkyl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen, can be substituted]; (25) a phenoxy group [wherein, on the phenyl ring, at least one selected from the group consisting of a Cl-Cβ phenyl alkoxy group, a C3-C8 cycloalkyl group, a C7-C10 alkoxy group, and a phenoxy group , is replaced]; (26) a naphthyloxy group; (27) a 2, 3-dihydrobenzofuryloxy group [wherein, in the 2, 3-dihydrobenzofuran ring, at least one oxo group can be substituted]; (28) a benzothiazolyloxy group [wherein, in the benzothiazole ring, at least one Cl-Cß alkyl group can be substituted]; (29) a 1, 2, 3, 4-tetrahydronaphthyloxy group [wherein, in the 1, 2, 3, 4-tetrahydronaphthalene ring, at least one oxo group can be substituted]; (30) a dibenzofuryloxy group; (31) a quinolyloxy group; (32) a Cl-Cβ alkoxy furyl group [wherein, in the furan ring, at least one Cl-Cβ alkoxycarbonyl group can be substituted]; (33) a C1-C6 alkoxy tetrazolyl group [wherein, in the tetrazole ring, at least one selected from the group consisting of a C1-C6 alkyl group phenyl and a C1-C6 alkyl group C3-C8 cycloalkyl can be substituted]; (34) a 1,2,4-oxadiazolyl C1-C6 alkoxy group [wherein, in the 1,2,4-oxadiazole ring, a phenyl group can be substituted (wherein, in the phenyl ring, at least one selected of the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]; (35) a Cl-Cβ benzothienyl alkoxy group [wherein, in the benzothiophene ring, at least one halogen atom can be substituted]; (3β) a C 1 -C 6 alkoxy isoxazolyl group [wherein, in the isoxazole ring, at least one C 1 -C 6 alkyl group can be substituted]; (37) a C1-C6 alkoxy 1,3,4-oxadiazolyl group [wherein, in the 1,3,4-oxadiazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least a C1-C6 alkyl group can be substituted)]; (38) a Cl-Cβ naphthyl alkoxy group; (39) a Cl-Cβ pyridyl alkoxy group (wherein, in the pyridine ring, at least one C1-Cß alkyl group substituted or unsubstituted with halogen can be substituted); (40) a Cl-Cβ thiazolyl alkoxy group [wherein, in the thiazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted)]; (41) a 1,2,4,4-tetrahydronaphthyl Cl-C 1 alkoxy group (wherein, in the 1, 2, 3, 4-tetrahydronaphthalene ring, at least one Cl-Cß alkyl group can be substituted); (42) a Cl-Cβ phenoxy alkoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen, and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen, can be substituted); (43) a Cl-Cβ carbamoyl alkoxy group [wherein, at the amino group, at least one selected from the group consisting of a C3-C8 cycloalkyl group and a phenyl group (wherein, at the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted by halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted) can be substituted; (44) a Cl-Cβ benzofuryl alkoxy group (wherein, in the benzofuran ring, at least one cyano group can be substituted); (45) an alkyl Cl-Cβ naphthyloxy group (wherein, in the naphthalene ring, at least one Cl-Cβ alkoxy group can be substituted); (46) a C 1 -C 6 alkyl benzothiazolyloxy group (wherein, in the benzothiazole ring, at least one C 1 -C 6 alkyl group can be substituted); (47) a C1-C6 alkyl quiniloxy group (wherein, in the quinoline ring, at least one C1-C6 alkyl group can be substituted); (48) a C 1 -C 6 alkyl 2,3-dihydrobenzofuryloxy group (wherein, in the 2,3-dihydrobenzofuran ring, at least one selected from the group consisting of a C 1 -C 6 alkyl group and an oxo group can be substituted); (49) a C1-C6 alkyl 1,2,3,4-tetrahydronaphthyloxy group (wherein, in the 1, 2, 3, 4-tetrahydronaphthalene ring, at least one oxo group can be substituted); (50) a 2,3-dihydro-lH-indenyloxy C1-C6 alkyl group (wherein, in the 2, 3-dihydro-lH-indene ring, at least one oxo group can be substituted); (51) a C 1 -C 6 alkyl benzoxathiolanyloxy group (wherein, in the benzoxathiolane ring, at least one oxo group can be substituted); (52) a C1-C6 alkyl isoquinolyloxy group; (53) a Cl-Cβ pyridyloxy alkyl group; (54) a Cl-Cβ dibenzofuryloxy alkyl group; (55) a C1-C6 alkyl group 2H-1-benzopyranyloxy (wherein, in the 2H-1-benzopyran ring, at least one oxo group can be substituted); (56) a C 1 -C 6 alkyl benzoisoxazolyloxy group; (57) a C 1 -C 6 alkyl group benzofurazanyloxy; (58) a C 1 -C 6 alkyl quinoxalyloxy group; (59) a C1-C6 alkyl group substituted with Cl-C6 alkoxy Cl-Cβ alkoxy; (60) a C1-C6 alkyl group substituted with Cl-C6 alkoxy thienyl (wherein, in the thiophene ring, at least one halogen atom can be substituted); (61) a C1-C6 alkyl group substituted with C2-C6 alkenyloxy phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted); (62) a C1-C6 alkyl group substituted with Cl-Cβ quinolyl alkoxy; and (63) a Cl-Cß alkyl group substituted with Cl-Cβ piperidylcarbonyl alkoxy, and in addition, R7 and R8 together can form a group = C (R29) (R30), wherein R29 and R30 each identically or differently represent a hydrogen atom, Cl-Cß alkyl group, or phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or not substituted by halogen, can be substituted]); (iii) a group represented by the following chemical formula (36): (wherein Wi I is the same as above, and R 13 represents: a 2, 3-dihydro-lH-indenyl group, a benzothienyl group, a C2-C10 alkenyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C4 alkylenedioxy group, a C1-C4 alkylthio group, a benzoyl group, a cyano group, a nitro group, a C2-C6 alkanoyloxy group, an amino group which may have a Cl-Cβ alkyl group as a substituent, a hydroxyl group, a Cl-Cβ phenyl alkoxy group, a phenoxy group, a substituted or unsubstituted Cl-Cß alkyl group with halogen, and a substituted or unsubstituted C 1 -C 6 alkoxy group with halogen, it can be substituted], a C2-C6 alkenyl group naphthyl, a C1-Cβ benzofuryl alkyl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, an alkyl group Cl -Cß substituted or unsubstituted with halogen, and a substituted C1-C6 alkoxy group or not subs substituted with halogen, can be substituted]; a C2-C6 alkenyl benzothienyl group; a C2-C6 alkenyl benzothiazolyl group [wherein, in the benzothiazole ring, at least one C1-C6 alkyl group can be substituted]; an alkyl Cl-Cβ phenyl group [wherein, in the phenyl ring, at least one selected from the following group is substituted: a piperidinyl group (in the piperidine ring, at least one phenoxy group can be substituted [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and an alkoxy Cl group -Cβ substituted or unsubstituted with halogen, can be substituted]), a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or not substituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, is substituted), and a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted)]; a Cl-Cβ-biphenyl alkyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or not substituted with halogen, can be replaced]; a Cl-Cβ benzoyl alkyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be replaced]; an amino group wherein at least one selected from the following group can be substituted: a C1-C6 alkyl group, a C1-C6 alkoxycarbonyl group, and a C1-C3 alkyl phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and an alkoxy Cl group) -Cβ substituted or unsubstituted with halogen, can be substituted), a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted]; a Cl-Cß amino alkyl group wherein at least one selected from the group consisting of a Cl-Cß alkyl group and a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom , a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted) can be substituted; a C2-C6 alkenyl benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be replaced]; a piperidyl group [wherein, in the piperidine ring, at least one C2-C6 alkenyl phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group Cl-Cβ substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted)]; a Cl-Cß alkyl group substituted with ferrocene; an indolyl Cl-C6 alkyl group (wherein, in the indole ring, at least one halogen atom can be substituted); a C2-C6 alkynyl group phenyl; a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a C1-C4 alkylenedioxy group, a phenyl group, a C1-C3 alkoxycarbonyl group, a hydroxyl group, and a phenoxy group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), is substituted]; a benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom and a C1-C6 alkyl group can be substituted]; a benzothiazolinyl group [wherein, in the benzothiazoline ring, at least one oxo group can be substituted]; a benzothienyl group [wherein, in the benzothiophene ring, at least one halogen atom can be substituted]; a naphthyl group; a 1, 2, 3, 4-tetrahydroquinolyl group [wherein, in the 1, 2, 3, 4-tetrahydroquinoline ring, at least one selected from the group consisting of an oxo group and a Cl-Cß alkyl group can be substituted ]; a benzoisoxazolyl group; a 2, 3-dihydrobenzofuryl group; a 1,2-dihydroquinolyl group [wherein, in the 1,2-dihydroquinoline ring, at least one oxo group can be substituted]; a 1, 2, 3, 4-tetrahydroquinazolinyl group [wherein, in the 1, 2, 3, 4-tetrahydroquinazoline ring, at least one selected from the group consisting of an oxo group and a Cl-Cß alkyl group can be substituted ]; a benzocycloheptyl group; a Cl-Cβ phenoxy alkyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or not substituted with halogen, can be replaced]; a C 1 -C 6 alkyl group substituted with benzothienyl [wherein, in the benzothiophene ring, at least one halogen atom can be substituted]; a Cl-Cß alkyl group substituted with naphthyl (wherein, in the naphthalene ring, at least one Cl-Cβ alkoxy group can be substituted); a C1-C6 alkyl group substituted with pyridyl [wherein, in the pyridine ring, at least one halogen atom can be substituted]; a C 1 -C 3 alkyl group substituted with furyl [wherein, in the furan ring, at least one nitro group can be substituted]; a Cl-Cß alkyl group substituted with thienyl [wherein, in the thiophene ring, at least one halogen atom can be substituted]; a thiazolyl-substituted Cl-Cß alkyl group [wherein, in the thiazole ring, at least one selected from the group consisting of a Cl-Cß alkyl group and a phenyl group (wherein, in the phenyl ring, at least one selected of the group consisting of a halogen atom and a Cl-Cß alkyl group substituted or unsubstituted with halogen can be substituted) can be substituted]; a Cl-Cβ alkyl group substituted with tetrazolyl [wherein, in the tetrazole ring, at least one Cl-Cß alkyl group can be substituted]; a Cl-Cß alkyl group substituted with isoxazolyl [wherein, in the isoxazole ring, at least one Cl-Cß alkyl group can be substituted]; a Cl-Cß alkyl group substituted with 1,2,4-oxadiazolyl [wherein, in the 1,2,4-oxadiazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, an alkyl group Cl-Cβ can be substituted)]; or a C 1 -C 6 alkyl group substituted with benzofurazanyl); (iv) a group represented by the following chemical formula (37): (wherein R 14 represents: a phenylamino group [wherein, at the N position of the phenylamino group, a C 1 -C 6 alkyl group can be substituted, and on the phenyl ring of the phenylamino group, at least one substituted C 1 -C 6 alkoxy group or not substituted by halogen can be substituted], a piperidyl group [wherein, in the piperidine ring, at least one selected from the group consisting of a phenoxy group (wherein, on the phenyl ring, a substituted C 1 -C 6 alkoxy group or not substituted by halogen can be substituted) and an amino group (wherein, at the amino group, at least one selected from the group consisting of a C1-C6 alkyl group and a phenyl group [wherein, on the phenyl ring, less one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted] can be substituted as a substituent ) can be substitute gone]; a piperazinyl group [wherein, in the piperazine ring, at least one selected from the following group can be substituted: a Cl-Cβ alkoxycarbonyl group, a Cl-Cβ alkyl phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), a C2-C6 alkenyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, may be substituted), and a benzoyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted by halogen, and an alkoxy Cl group) -Cß substituted or not substituted with halogen, can be substituted)]; a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen, and a substituted or unsubstituted Cl-Cβ alkoxy group with halogen, it can be replaced); a homopiperazinyl group [wherein, in the homopiperazine ring, at least one selected from the group consisting of a C1-Cβ alkoxycarbonyl group and a C1-C3 alkyl phenyl group (wherein, in the phenyl ring, at least one selected from the group which consists of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted) can be substituted]; or a phenoxy group [wherein, on the phenyl ring, at least one selected from the group consisting of a C1-C6 alkoxy group substituted or unsubstituted by halogen and a phenyl group substituted by phenoxy (wherein, on the phenyl ring, at least one C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted), can be substituted]); (v) a group represented by the following chemical formula (38): (where R13 is the same as the previous one, and a dotted line represents that the link can be a double bond); (vi) a homopiperazinyl group (wherein, in the homopiperazine ring, at least one selected from the following group can be substituted: a C1-C6 alkoxycarbonyl group, a C1-C6 alkyl phenyl group [wherein, in the phenyl ring, less one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted]; a phenyl group [in where, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen, and a C1-Cß alkoxy group substituted or unsubstituted with halogen, can be substituted], a Cl-Cß phenyl alkoxycarbonyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted by halogen, and an alkoxy group Cl-Cß s either substituted or not substituted with halogen, can be replaced]; a phenylcarbamoyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen, and a substituted or unsubstituted Cl-Cβ alkoxy group with halogen, it can be replaced]; a C2-C6 alkenyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C3 alkyl group substituted or unsubstituted by halogen, and a C1-C [beta] alkoxy group substituted or not substituted with halogen, can be replaced]; and a benzoyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and a substituted C1-Cβ alkoxy group or not substituted with halogen, can be replaced]); (vii) a group represented by the following chemical formula (39): (wherein R19 represents a Cl-Cβ alkoxy group, and R20 represents a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or not substituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted]); (viii) a -CHR20R21 group (wherein R20 is the same as the above, and R21 represents an amino group which may have a Cl-Cß alkyl group as a substituent); (ix) a 1,2,3,4-tetrahydroisoquinolyl group (wherein, in the 1, 2, 3, 4-tetrahydroisoquinoline ring, at least one amino group can be substituted [where, in the amino group, at least one selected from the group consisting of a C1-C3 alkyl phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted) and a C1-C6 alkyl group can be substituted]); (x) an oxazolyl group (wherein, in the oxazole ring, at least one selected from the following group can be substituted: a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted], a Cl-Cß alkyl group, and a piperidyl group [wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cß alkoxy group substituted or unsubstituted with halogen, can be substituted)]); (xi) an isoindolinyl group (wherein, in the isoindoline ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and a substituted C1-Cβ alkoxy group or not substituted with halogen, can be substituted); (xii) a thiazolyl group (wherein, in the thiazole ring, at least one selected from the following group can be substituted: a Cl-Cβ phenoxy alkyl group [wherein, in the phenyl ring, at least one selected from the group consisting of of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen, can be substituted]; a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted Cl-Cß alkoxy group with halogen, it can be replaced]; a C1-C3 alkyl phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or not substituted with halogen, can be replaced]; a group - (W?) or NR31R32 [where Wi and o are the same as above, and R31 and R32 each identically or differently represent a hydrogen atom, Cl-Cß alkyl group, phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group Cl-Cβ substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), or Cl-Cβ phenyl alkyl group (wherein, in the phenyl ring, at least one selected from the a group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen, can be substituted)]; a piperazinyl group [wherein, in the piperazine ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group) substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]; a piperidyl group [wherein, in the piperidine ring, at least one selected from the group consisting of a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group Cl-Cβ substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted) and a Cl-Cβ phenyl alkyl group can be substituted]; and a phenoxy group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be replaced]); (xiii) a Cl-Cß alkyl group substituted with hydroxyl group; (xiv) a Cl-Cβ oxazolyl alkyl group [wherein, in the oxazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted)]; (xv) an isoxazolyl group [wherein, in the isoxazoline ring, at least one phenyl ring can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1 -C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]; (xvi) a benzoxazolyl group (wherein, in the benzoxazole ring, at least one halogen atom can be substituted); (xvii) a phenylthio group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted C1-C6 alkoxy group or not substituted with halogen, can be substituted); (xviii) a benzoimidazolyl group [wherein, in the benzoimidazole ring, at least one selected from the group consisting of a halogen atom and a Cl-Cβ phenyl alkyl group (wherein, in the phenyl ring, at least one selected from the group group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted) can be substituted]; (xiv) a pyrrolidinyl group [wherein, in the pyrrolidine ring, at least one amino group is substituted (wherein, in the amino group, at least one selected from the group consisting of a C1-C6 alkyl group and a phenyl group) (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can be replaced) can be replaced)]; (xx) a phenylsulfonyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted C1-C6 alkoxy group or not substituted with halogen, can be substituted); (xxi) an imidazolyl group [wherein, on the imidazole ring, at least one phenyl group is substituted (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-alkyl group C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]; and (xxii) a phenylsulphinyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be replaced)]; (s) an imidazolyl group (wherein, in the imidazole ring, at least one selected from the group consisting of a halogen atom and a nitro group can be substituted); (t) an isoindolinyloxy group [wherein, in the isoindoline ring, at least one selected from the following group can be substituted: a Cl-Cβ alkoxycarbonyl group, a Cl-Cβ alkyl phenyl group (wherein, in the phenyl ring, less one selected from the group consisting of a benzofuryl group, a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), a C2-C6 alkenyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted C1-Cβ alkoxy group or unsubstituted with halogen, can be substituted), an alkyl Cl-Cß furyl group [wherein, in the furan ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group Cl-Cβ substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted)], a Cl-Cβ pyridyl alkyl group [wherein, in the pyridine ring, at least one selected of the group consisting of a furyl group and a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted) can be substituted], a Cl-Cß benzofuryl alkyl group (wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom , a Cl-Cß alkyl group substituted or not substituted by halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted by halogen, can be substituted), a Cl-Cß benzothienyl alkyl group (wherein, in the benzothiophene ring, minus one atom d and halogen can be substituted), a C2-C6 alkenyl benzofuryl group (wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), a thiazolyl group [wherein, in the thiazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), and an alkyl Cl group -Cß phenoxy (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, can to be replaced)]; (u) a benzothiazolidynyloxy group [wherein, in the benzothiazolidine ring, at least one selected from the group consisting of an oxo group and a Cl-Cβ phenyl alkyl group (wherein, in the phenyl ring, at least one selected from the group which consists of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), can be substituted]; (v) an indolyloxy group [wherein, in the indole ring, at least one Cl-Cß phenyl alkyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted)]; () a pyrrolidinyl group [wherein, in the pyrrolidine ring, at least one amino group is substituted (wherein, in the amino group, at least one selected from the group consisting of a C1-C6 alkyl group and a phenyl group ( wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can to be replaced) can be replaced)]; (x) an indolinyl group (wherein, in the indoline ring, at least one halogen atom can be substituted); and (y) an indolinyloxy group [wherein, in the indoline ring, at least one selected from the group consisting of a Cl-Cß phenyl alkyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted) and an oxo group can be substituted]. The present invention provides a compound 2, 3-dihydro-6-nitroimidazo [2, 1-b] oxazole, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to the above-mentioned general formula (1), wherein R2 represents a group described in one of any of (a) through (c), (e) through (h), (j) through (q), and (s) through (and). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R2 represents the group described in (d). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R2 represents the group described in (i). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above. (1), where R2 represents the group described in (r). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to the general formula mentioned above (1), wherein R1 represents a hydrogen atom. The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R 1 represents a Cl-Cß alkyl group. The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to the general formula mentioned above (1), wherein R1 and - (CH2) nR2 can link to each to form a spiro ring with the carbon atom adjacent thereto, represented by the following formula (30): wherein RRR represents a piperidyl group [wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]. The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a Cl-Cß alkyl group and R 3 represents the group described in (i). The present invention provides a 2,3-dihydro-β-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a Cl-Cß alkyl group and R 3 represents the group described in (ii). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a C 1 -C 6 alkyl group and R 3 represents the group described in (iii). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a C 1 -C 6 alkyl group and R 3 represents the group described in (iv). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R1 represents a hydrogen atom or a C1-C6 alkyl group and R3 represents the group described in (v). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a C 1 -C 6 alkyl group and R 3 represents the group described in (vi). The present invention provides a 2, 3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a Cl-Cß alkyl group and R 3 represents the group described in (vii). The present invention provides a 2,3-dihydro-β-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R1 represents a hydrogen atom or a Cl-C6 alkyl group and R3 represents the group described in (viii). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a Cl-Cß alkyl group and R 3 represents the group described in (ix). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a Cl-Cß alkyl group and R 3 represents the group described in (x). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a Cl-Cß alkyl group and R 3 represents the group described in (xi). The present invention provides a 2,3-dihydro-6-nitroi idazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1) , wherein R 1 represents a hydrogen atom or a C 1 -C 6 alkyl group and R 3 represents the group described in (xii). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a Cl-Cß alkyl group and R 3 represents the group described in (xiii). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a Cl-Cß alkyl group and R 3 represents the group described in (xiv). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a Cl-Cß alkyl group and R 3 represents the group described in (xv). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a C 1 -C 6 alkyl group and R 3 represents the group described in (xvi). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a C 1 -C 6 alkyl group and R 3 represents the group described in (xvii).

The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a C 1 -C 6 alkyl group and R 3 represents the group described in (xviii). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a C 1 -C 6 alkyl group and R 3 represents the group described in (xix). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a C 1 -C 6 alkyl group and R 3 represents the group described in (xx). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R1 represents a hydrogen atom or a C1-C6 alkyl group and R3 represents the group described in (xxi). The present invention provides a 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof in accordance with the general formula mentioned above (1), wherein R 1 represents a hydrogen atom or a Cl-Cß alkyl group and R 3 represents the group described in (xxii). In the compounds represented by the formula (1) of the present invention, particularly preferred are as follows: 2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethylbenzyloxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethylbenzyloxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethylbenzyloxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2-. { 4- [4- (4-chlorophenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2-. { 4- [4- (4-chlorophenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3- dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [4- (4-chlorophenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethylancinamyl) piperazin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethylancinamyl) piperazin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethylancinamyl) piperazin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2-. { 4- [4- (4-t ifluoromethoxycinnamyl) piperazin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethoxycinnamyl) piperazin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethoxycinnamyl) piperazin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethylphenoxymethyl) pi? Eridin-1-yl] phenoxymethyl} -2, 3- dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethylphenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethylphenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 6-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyloxy) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -6-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyloxy) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -6-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyloxy) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 6-nitro-2-. { 4- [4- (4-trifluoromethoxyphenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -6-nitro-2-. { 4- [4- (4-trifluoromethoxyphenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -6-nitro-2-. { 4- [4- (4-trifluoromethoxyphenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 6-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -6-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -6-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethyl-methoxybenzyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2- [4-. { 4- [4- (4-trifluoromethylphenyl) piperazin-1-yl] piperidin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-β-nitro-2- [4-. { 4- [4- (4-trifluoromethylphenyl) piperazin-1-yl] piperidin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-β-nitro-2- [4-. { 4- [4- (4-trifluoromethylphenyl) piperazin-1-yl] piperidin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2- [4-. { 4- [4- (4-trifluoromethoxyphenoxy) benzyl] piperazin-1-yl} phenoxymethyl] -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2- [4-. { 4- [4- (4-trifluoromethoxyphenoxy) benzyl] piperazin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2- [4-. { 4- [4- (4-trifluoromethoxyphenoxy) benzyl] piperazin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, 6-nitro-2- [4-. { 4- [3- (4-trifluoromethoxyphenyl) propyl] piperidin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, (R) -6-nitro-2- [4-. { 4- [3- (4-trifluoromethoxyphenyl) propyl] piperidin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, (S) -6-nitro-2- [4-. { 4- [3- (4-trifluoromethoxyphenyl) propyl] piperidin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2-. { 4- [2- (4-trifluoromethoxyphenyl) oxazol-4-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-β-nitro-2-. { 4- [2- (4-trifluoromethoxyphenyl) oxazol-4-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [2- (4-trifluoromethoxyphenyl) oxazol-4-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 6-nitro-2-. { 4- [4- (4-chlorophenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -6-nitro-2-. { 4- [4- (4-chlorophenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -6-nitro-2-. { 4- [4- (4-chlorophenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-β-nitro-2-. { 4- [4- (5-trifluoromethylbenzofuran-2-yl) methylpiperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2-. { 4- [4- (5-trifluoromethylbenzofuran-2-yl) methylpiperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [4- (5-trifluoromethylbenzofuran-2-yl) methylpiperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-β-nitro-2-. { 4- [2- (4-chlorophenyl) oxazol-4-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2-. { 4- [2- (4-chlorophenyl) oxazol-4-yl] phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [2- (4-chlorophenyl) oxazol-4-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, β-nitro-2-. { 4- [4- (4-trifluoromethylphenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -6-nitro-2-. { 4- [4- (4-trifluoromethylphenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -6-nitro-2-. { 4- [4- (4- trifluoromethylphenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2-. { 4- [4- (4-Bromocyamyl) piperazin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2-. { 4- [4- (4-Bromocyamyl) piperazin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [4- (4-Bromocyamyl) piperazin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2- [2- (4-trifluoromethoxyphenyl) -1,2,3,4-tetrahydroisoquinolin-6-yloxymethyl] -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2- [2- (4-trifluoromethoxyphenyl) -1,2,3,4-tetrahydroisoquinolin-6-yloxymethyl] -2, 3-dihydroimidazo [2, 1-b] oxazole, and (S) -2-methyl-6-nitro-2- [2- (4-trifluoromethoxyphenyl) -1,2,3,4-tetrahydroisoquinoline-6 -yloxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole. The present invention provides a pharmaceutical composition which is an antitubercular agent comprising, as an active ingredient, the compound 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole, optically active form thereof, or pharmacologically salt acceptable of the same represented by the general formula (1). In particular, the present invention provides a pharmaceutical composition which is an antitubercular agent comprising, as an active ingredient, at least one compound selected from the compounds 2,3-dihydro-6-nitroimidazo- [2, 1-b] oxazole which are preferred compounds listed above. The present invention provides a method for producing a compound represented by the general formula (1): (wherein R1, R2, and n have the same definitions as described above), the method comprises: a reaction of a 4-nitroimidazole compound represented by the following general formula (2): (wherein Xi represents a halogen atom or a nitro group), with an epoxy compound represented by the following general formula (3a): (wherein R1, R2 and n have the same definitions as described above), to obtain a compound represented by the following general formula (4a): (wherein R1, R2 and n have the same definitions as described above, and X1 represents a halogen atom or a nitro group); and a rear ring closure of the obtained compound represented by the above general formula (4a). The present invention provides a method for producing a compound represented by the following general formula (lw): (wherein R, 1A represents a hydrogen atom, or a C1-C6 alkyl group, R2A represents a group described in any one of any of (a) through (y) as defined above, and n represents an integer between 0 and 6 ), the method comprises: a reaction of a compound represented by the following general formula (3b) (3b) (wherein R1A is the same as described above, and X1 represents a halogen atom or nitro group), with a compound R2AH (5) or a salt thereof (wherein R2A represents a group described in one of any of ( a) to (y) as defined above), to obtain a compound represented by the following general formula (4c): (wherein R1 has the same definition as described above, R2A represents a group described in one of any of (a) through (y) as defined above, and X1 represents a halogen atom or a nitro group); and a rear ring closure of the obtained compound represented by the above general formula (4c). The present invention provides a method for producing a compound represented by the following general formula (lw): (wherein R1A, R2A, and n have the same definitions as described above), the method comprises: a reaction of a compound represented by the following general formula (6): (wherein R1A and n have the same definitions as described above, and R15 represents a C1-C6 alkylsulfonyl group or a benzenesulfonyl group in which a C1-C6 alkyl group may be substituted), with a R2AH compound (5) or a salt thereof (wherein R2A represents a group described in any one of any of (a) to (y) as defined above).

BEST MODE FOR CARRYING OUT THE INVENTION In the compounds of the present invention, particularly preferred groups of R1, R2, R3 are as follows. R1 is preferably a hydrogen atom or C1-C6 alkyl group. R is preferably a group (d), (i) or (r) as defined above. R3 is preferably a group (ii), (iii) or (x) as defined above. R8 is preferably a group (1), (2), (4), (5), (8), (24) or (25) as defined above. R13 is preferably a C2-C10 alkenyl phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkylene dioxy Cl-C4 group, an alkylthio Cl-Cß group, a benzoyl group , a cyano group, a nitro group, a C2-C6 alkanoyloxy group, an amino group which may have Cl-Cß alkyl group as a substituent (s), a hydroxyl group, a C1-Cβ alkoxy phenyl group, a phenoxy group, a Cl-Cß alkyl group substituted or unsubstituted by halogen and a Cl-Cß alkoxy group substituted or unsubstituted by halogen, can be substituted] or a Cl-Cß alkenyl phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a piperidinyl group (wherein, in the piperidine ring, at least one phenoxy group can be substituted [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halo geno and a Cl-Cß alkoxy group substituted or unsubstituted with halogen, can be substituted]), a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and an alkoxy Cl group) -Cβ substituted or unsubstituted with halogen, can be substituted) and a phenoxy group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), can be substituted]. In this specification, each group represented by R1, R2, R3 or the like is specifically as follows: Examples of halogen atoms are fluorine atom, chlorine atom, bromine atom and iodine atom. A Cl-Cß alkyl group is a straight or branched alkyl group containing 1 to 6 carbon atoms, examples of which include a methyl group, ethyl group, n-propyl group, isopropyl group, n-butyl group, isobutyl group, tert-butyl group, sec-butyl group, n-pentyl group, neopentyl group, n-hexyl group, isohexyl group, 3-methylpentyl group or the like. A C1-C6 alkoxy group is a group containing a C1-C6 alkyl group as defined above and an oxygen atom, examples of which include a methoxy group, ethoxy group, n-propoxy group, isopropoxy group, n-group butoxy, isobutoxy group, tert-butoxy group, sec-butoxy group, n-pentoxy group, neopentoxy group, n-hexyloxy group, isohexyloxy group, 3-methylpentoxy group or the like.

A Cl-Cß alkyl group substituted or unsubstituted by halogen is a straight or branched alkyl group containing 1 to 6 carbon atoms as defined above and optionally substituted by 1 to 7 halogen atoms, examples of which include a methyl group , ethyl group, n-propyl group, isopropyl group, n-butyl group, isobutyl group, tert-butyl group, sec-butyl group, n-pentyl group, neopentyl group, n-hexyl group, isohexyl group, 3-methylpentyl group , fluoromethyl group, difluoromethyl group, trifluoromethyl group, chloromethyl group, dichloromethyl group, trichloromethyl group, bromomethyl group, dibromomethyl group, dichlorofluoromethyl group, 2,2,2-trifluoroethyl group, pentafluoroethyl group, 2-chloroethyl group, group 3, 3, 3-trifluoropropyl, heptafluoropropyl group, heptafluoroisopropyl group, 3-chloropropyl group, 2-chloropropyl group, 3-bromopropyl group, 4,4,4-trifluorobutyl group, 4, 4, 4, 3, 3-pentafluorobutyl, group 4 chlorobutyl, 4-bromobutyl group, 2-chlorobutyl group, 5,5,5-trifluoropentyl group, 5-chloropentyl group, 6,6,6-trifluorohexyl group, 6-chlorohexyl group or the like. A C1-C6 alkoxy group substituted or unsubstituted with halogen is a C1-C6 alkoxy group as defined above and an alkoxy group substituted by 1 to 7 halogen atoms, examples of which include a methoxy group, ethoxy group, group n -propoxy, isopropoxy group, n-butoxy group, isobutoxy group, tert-butoxy group, sec-butoxy group, n-pentoxy group, neopentoxy group, n-hexyloxy group, isohexyloxy group, 3-methylpentoxy group, fluoromethoxy group, difluoromethoxy group , trifluoromethoxy group, chloromethoxy group, dichloromethoxy group, trichloromethoxy group, bromomethoxy group, dibromomethoxy group, dichloro-fluoromethoxy group, 2,2,2-trifluoroethoxy group, pentafluoroethoxy group, 2-chloroethoxy group, 3, 3, 3-trifluoropropoxy group, heptafluoropropoxy group, heptafluoroisopropoxy group, 3-chloropropoxy group, 2-chloropropoxy group, 3-bromopropoxy group, 4,4,4-trifluorobutoxy group, 4, 4, 4, 3, 3-pentafluorobutoxy group, 4-chlorobutoxy group, group 4 -bromobutoxy, 2-chlorobutoxy group, group 5 , 5, 5-trifluoropentoxy, 5-chloropentoxy group, 6,6,6-trifluorohexyloxy group, 6-chlorohexyloxy group or the like. A phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted) includes a phenoxy group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), for example, a phenoxy group, 2-fluorophenoxy group, 3-fluorophenoxy group, 4-fluorophenoxy group, 2-chlorophenoxy group, group 3 chlorophenoxy, group 4-chlorophenoxy, group 2-bromophenoxy, group 3-bromo-phenoxy, group 4-bromophenoxy, group 2, 3-dichlorophenoxy, group 3, 4-dichlorophenoxy, group 2, 4-dichlorophenoxy, group 3, 4, 5-trichlorophenoxy, group 2, 4, 6-trichlorophenoxy, group 2, 3, 4, 5, 6-pentafluoro phenoxy, 2-methylphenoxy group, 3-methylphenoxy group, 4-methylphenoxy group, 2-ethylphenoxy group, 3-ethylphenoxy group, 4-ethylphenoxy group, 4-n-propylphenoxy group, 4-tert-butylphenoxy group 4-n -butylphenoxy, 2-trifluoromethylphenoxy group, 3-trifluoromethylphenoxy group, 4-trifluoromethylphenoxy group, 2-pentafluoroethylphenoxy group, 3-pentafluoroethylphenoxy group 2, 3-dimethylphenoxy, group 3, 4, 5-trimethylphenoxy, 4-n-pentylphenoxy group , 4-n-hexylphenoxy group, 2-methoxyphenoxy group, 3-methoxyphenoxy group, 4-methoxyphenoxy group, 2-ethoxyphenoxy group, 3-ethoxyphenoxy group, 4-ethoxyphenoxy group, 4-n-propoxyphenoxy group, 4-tert-group butoxyphenoxy, 4-n-butoxyphenoxy group, 2-trifluoromethoxyphenoxy group, 3-trifluoromethoxyphenoxy group, 4-trifluoromethoxyphenoxy group, group 2-pentafluoroethoxyphenoxy, group 3-pentafluoroethoxyphenoxy, group 2, 3-dimethoxyphenoxy, group 3, 4, 5-trimethoxyphenoxy, group 4-n-pentyloxyphenoxy, group 4-n-hexyloxyphenoxy or the like. A piperidyl group [wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted Cl-Cβ alkyl group) or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted)] includes a piperidyl group [wherein, in the piperidine ring, 1 to 3 phenoxy groups can be substituted (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 groups selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, they can be substituted)], for example, a 1-piperidyl group, 2-piperidyl group, 3-piperidyl group, 4-piperidyl group, 4-phenoxy-1-piperidyl group, 2, 4-diphenoxy-1-piperidyl group, Group 2, 4, 6-triphenoxy-1-piperidyl, group 2- (2-flu) orophenoxy) -1-piperidyl, 3- (3-fluorophenoxy) -2-piperidyl group, 4- (4-fluorophenoxy) -3-piperidyl group, 2- (2-chlorophenoxy) -4-piperidyl group, group 3- ( 3-chlorophenoxy) -5-piperidyl, 4- (4-chlorophenoxy) -2-piperidyl group, 5- (2-bromophenoxy) -2-piperidyl group, β- (3-bromophenoxy) -3-piperidyl group, group 4 - (4-bromophenoxy) -1-piperidyl, 3- (2, 3-dichlorophenoxy) -2-piperidyl group, 4- (3,4-dichlorophenoxy) -3-piperidyl group, 3- (2,4-dichlorophenoxy) group ) -4-piperidyl, 2- (3,4,5-trichlorophenoxy) -3-piperidyl group, 6- (2, 4, ß-trichlorophenoxy) -2-piperidyl group, group 3- (2, 3, 4, 5, β-pentafluorophenoxy) -1-piperidyl, 4- (2-methylphenoxy) -1-piperidyl, 5- (3-methylphenoxy) -2-piperidyl, 6- (4-methylphenoxy) -3-piperidyl group, group 1- (2-ethylphenoxy) -4-piperidyl, 2- (3-ethylphenoxy) -1-piperidyl group, 3- (4-ethylphenoxy) -2-piperidyl group, 4- (4-n-propylphenoxy) -3 group -piperidyl, 3- (4-tert-butylphenoxy) -4-piperidyl group, 2- (4-n-butylphenoxy) -3-piperidyl group , 1- (2-trifluoromethylphenoxy) -2-piperidyl group, 2- (3-trifluoromethylphenoxy) -1-piperidyl group, 3- (4-trifluoromethylphenoxy) -1-piperidyl group, l- (2-pentafluoroethylphenoxy) -4 group -piperidyl, l- (3-pentafluoroethylphenoxy) -4-piperidyl group, 4- (2,3-dimethylphenoxy) -1-piperidyl group, 1- (3, 4, 5-trimethylphenoxy) -4-piperidyl group, group 1 - (4-n-pentylphenoxy) -4-piperidyl, 4- (4-n-hexylphenoxy) -1-piperidyl group, 4- (2-methoxyphenoxy) -1-piperidyl group, 1- (3-methoxyphenoxy) - 4-piperidyl, 1- (4-methoxyphenoxy) -4-piperidyl group, 2- (2-ethoxyphenoxy) -3-piperidyl group, 3- (3-ethoxyphenoxy) -4-piperidyl group, 4- (4-ethoxyphenoxy) group ) -3-piperidyl, 3- (4-n-propoxyphenoxy) -2-piperidyl group, 2- (4-tert-butoxyphenoxy) -1-piperidyl group, 1- (4-n-butoxyphenoxy) -2-piperidyl group , 2- (2-trifluoromethoxyphenoxy) -3-piperidyl group, 3- (3-trifluoromethoxyphenoxy) -4-piperidyl group, 4- (4-trifluoromethoxyphenoxy) -3-piperidyl group, 3- (2-pentafluoroethoxyphenoxy) -2 group -piperidyl , 2- (4-pentafluoroethoxyphenoxy) -1-piperidyl group, l- (2,3-dimethoxyphenoxy) -4-piperidyl group, 4 - (3,4,5-trimethoxyphenoxy) -1-piperidyl group, group 4 (4-n-pentyloxyphenoxy) -1-piperidyl, 4- (4-n-hexyloxyphenoxy) -1-piperidyl group or the like. A phenyl group (wherein, in the phenyl ring, at least one piperidyl group can be substituted [wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, in the phenyl group, at least one selected of the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted)]) includes a phenyl group (wherein, in the phenyl ring, 1 to 3 piperidyl groups can be substituted [where, in the piperidine ring, 1 to 3 phenoxy groups can be substituted (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted)]), for example, a phenyl group, 4- (1-piperidyl) phenyl group, 2, 4-di (1-piperidyl) phenyl group , 2,4,6-tri (l-piperidyl) phenyl group, 3- (4-piperidyl) phenyl group, 2- (2-piperidyl) phenyl group, 4- (3-piperidyl) phenyl group, 3- ( 4-phenoxy-1-piperidyl) phenyl, 2- (2,4-diphenoxy-1-piperidyl) phenyl group, 4- (2,4,6-triphenoxy-1-piperidyl) phenyl group, 3- [2- (2-fluorophenoxy) -1-piperidyl] phenyl, 2- [3- (3-fluorophenoxy) -2-piperidyl] phenyl group, 4- [4- (4-fluorophenoxy) -3-piperidyl] phenyl group 3 - [2- (2-chlorophenoxy) -4-piperidyl] phenyl, 2- [3- (3-chlorophenoxy) -5-piperidyl] phenyl group, 4- [4- (4-chlorophenoxy i) -2-piperidyl] phenyl, 3- [5- (2-bromophenoxy) -2-piperidyl] phenyl group, 2- [ß- (3-bromophenoxy) -3-piperidyl] phenyl group, group 4- [4 - (4-bromophenoxy) -l-piperidyl] phenyl, 3- [3- (2,3-dichlorophenoxy) -2-piperidyl] phenyl group, 2- [4- (3,4-dichlorophenoxy) -3-piperidyl group] ] phenyl, 4- [3- (2,4-dichlorophenoxy) -4-piperidyl] phenyl group, 3- [2- (3,4,5-trichlorophenoxy) -3-piperidyl] phenyl group 2- [6] - (2,4,6-trichlorophenoxy) -2-piperidyl] phenyl, 4- [3- (2,3,4,5,6-pentafluorophenoxy) -1-piperidyl] phenyl group 3- [4- ( 2-methylphenoxy) -1-piperidyl] phenyl, 2- [5- (3-methylphenoxy) -2-piperidyl] phenyl group, group 4- [ß- (4-methylphenoxy) -3-piperidyl] phenyl, 3- [1- (2-ethylphenoxy) -4-piperidyl] phenyl group, 2- [2- (3-ethylphenoxy) -l-piperidyl group] ] phenyl, 4- [3- (4-ethylphenoxy) -2-piperidyl] phenyl group, 3- [4- (4-n-propylphenoxy) -3-piperidyl] phenyl group, 2- [3- (4- tert-butylphenoxy) -4-piperidyl] phenyl, 4- [2- (4-n-butylphenoxy) -3-piperidyl] phenyl group, 3- [l- (2-trifluoromethylphenoxy) -2-piperidyl] phenyl group 2- [2- (3-trifluoromethylphenoxy) -1-piperidyl] phenyl, 4- [3- (4-trifluoromethylphenoxy) -1-piperidyl] phenyl group, 3- [l- (2-pentafluoroethylphenoxy) -4-piperidyl group ] phenyl, 2- [l- (3-pentafluoroethylphenoxy) -4-piperidyl] phenyl group, 4- [4- (2,3-dimethylphenoxy) -1-piperidyl] phenyl group, group 3- [1- (3, , 5-trimethylphenoxy) -4-piperidyl] phenyl, 2- [1- (4-n-pentylphenoxy) -4-piperidyl] phenyl group, 4- [4- (4-n-hexylphenoxy) -l-piperidyl group] phenyl, 3- [4- (2-ethoxyphenoxy) -1-piperidyl] phenyl group, 2- [1- (3-methoxy-3-enoxy) -4-piperidyl] phenyl group, 4- [1- (4-methoxy) group enoxy) -4-piperidyl] phenyl, 3- [2- (2-ethoxy-enoxy) -3-piperidyl] phenyl group, 2- [3- (3-ethoxyphenoxy) -4-piperidyl] phenyl group 4- [ 4- (4-ethoxyphenoxy) -3-piperidyl] phenyl, 3- [3- (4-n-propoxy-enoxy) -2-piperidyl] phenyl group, 2- [2- (4-tert-butoxy-enoxo) group] -1-piperidyl] phenyl, 4- [1- (4-n-butoxifenoxi) -2-piperidyl] phenyl group, 3- [2- (2-trifluoromethoxyphenoxy) -3-piperidyl] phenyl group, group 2 - [3- (3-trifluoromethoxyphenoxy) -4-piperidyl] phenyl, 4- [4- (4-trifluoromethoxyphenoxy) -l-piperidyl] phenyl group, 3- [3- (2-pentafluoroethoxyphenoxy) group] 2-piperidyl] phenyl, 2- [2- (4-pentaf luor oethoxy-enoxy) -1-piperidyl] phenyl group, 4- [1- (2,3-dimethoxyphenoxy) -4-piperidyl] phenyl group 3 - [4- (3, 4, 5-trimethoxyphenoxy) -1-piperidyl] phenyl, 2- [4- (4-n-pentyloxyphenoxy) -l-piperidyl] phenyl group, group 4- [4- (4-n hexoxyx enoxi) -1-piperidyl] phenyl or the like. A phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted] includes a phenyl group unsubstituted or substituted by 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a group Cl-Cβ alkoxy substituted or unsubstituted with halogen, as defined above, eg, which include a phenyl group, 2-fluorofenyl group, 3-fluorofenyl group, 4-fluorophyl group, 2-chloro group, phenyl, 3-chlorofenyl group, 4-chlorofenyl group, 2-bromofenyl group, 3-bromofenyl group, 4-bromofenyl group, 2-iodophyl group, 3-iodophyl group, 4-iodophyl group, group 2, 3-difluorofenyl, group 3, 4-difluorofenyl, group 3, 5-difluorofenyl, group 2, 4-difluorofenyl, group 2, 6-difluorofenyl, group 2, 3-di chlorofenil, group 3, 4-dichlorophenyl, group 3, 5-di chlorofenyl, group 2, 4-dichlorofenyl, group 2, 6-dichlorofenyl, group 3, 4, 5-trif luorofenyl, group 3, 4, 5-tri chloro-f-enyl, group 2, 4, 6-trif luorofenyl, group 2, 4, 6-trichlorofenyl, 2-fluoro-4-bromophenyl group, 4-chloro-3-fluorophenyl group, group 2, 3, 4-trichlorophenyl, group 2, 3, 4, 5, 6-pentaf luorof enyl, 2, 4, 6-trimethyl-yl-enyl group, 4-n-butyl-enyl-group, 2,4-dimethyl-enyl-group, 2,3-dimethyl-enyl group-2, 6-dimethyl-enyl, group 3, 5- dimethylphenyl, group 2, 5-dimethylphenyl, group 3, 5-ditrif luoromethylphenyl, group 4-n-butoxifenyl, group 2, 4-dimethoxy-phenyl, group 2, 3-dimethoxyphenyl, group 2, 6-dimethoxyphenyl , group 3, 5-dimethoxyfine, group 2, 5-dimethoxyfine, group 2, 4,6-trimethoxyfyl, group 3, 5-ditrif luoromethoxyfill, group 3-chloro-4-methoxyfyl, group 2 -chloro-4-trifl uoromethoxyphenyl, 3-methyl-4-fluorophenyl group, 4-bromo-3-trif luoro-methylphenyl group, 2-methylphenyl group, 3-methylphenyl group, 4-methylphenyl group, 2-methyl-3-chlorophenyl group, 3-methyl-4-chlorofenyl group, 2-chloro-4-methylphenyl group 2 -methyl-3-f luorofenyl, 2-trifluoromethylphenyl group, 3-trifluoro-methylphenyl group, 4-trifluoromethylphenyl group, 2-pentafluoroethylphenyl group, 3-pentafluoroethylphenyl group, 4-pentafluoroethylphenyl group, 2-isopropylphenyl group, 3-isopropylphenyl group, 4-isopropyl-f-enyl group, 2-tert-butylphenyl group, 3-tert-butylphenyl group, 4-tert-butylphenyl group, 2-sec-butylphenyl group, 3-sec-butylphenyl group, 4-sec-butylphenyl group, 2-n-heptafluoropropylphenyl group, 3-n-heptafluoropropylfyl group, 4-n-heptafluoro-propylfyl group, 4-pentylphenyl group, 4-hexylphenyl group, 2-methoxyphenyl group, group 3 methoxyphenyl, 4-methoxyphenyl group, 3-chloro-2-methoxy-enyl group, 2-fluoro-3-methoxy-enyl group, 2-f-luoro-4-methoxyphenyl group, 2, 3, 4-trifluorofenyl group, Group 2-trif luoromethoxyphenyl, group 3-t rif luoromethoxyf enyl, group 4-trif luoro-methoxyfine, 3-fluoro-2-trifluoromethoxyphenyl group, 2-fluoro-3-trifluoromethoxyphenyl group, 3-f luoro-4-trif luoromethoxyfenyl group 3-chloro-2-group trifluoromethoxifenyl, 2-chloro-3-trifluoromethoxyfluoryl group, 3-chloro-4-trif luoromethoxyfenyl group, 2-pentaf luoroethoxyfenyl group, 3-pentaf luoroethoxyphenyl group, 4-pentafluoroethoxy phenyl group, group 3 chloro-2-pentaf luoroethoxyfenyl, 2-chloro-3-pentafluoroethoxyphenyl group, 3-chloro-4-pentafluoroethoxyphenyl group, 2-isopropoxyphenyl group, 3-isopropoxyphenyl group, 4-isopropoxyphenyl group, 2-tert-butoxifenyl group , 3-tert-butoxifenyl group, 4-tert-butoxifenyl group, 2-sec-butoxifenyl group, 3-sec-butoxhoxyphenyl group, 4-sec-butoxyphenyl group, 2-n-heptafluoropropoxyphenyl group, 3-n-group heptafluoropropoxyphenyl, 4-n-heptafluoropropoxy-phenyl group, 4-n-pentoxyphenyl group, 4-n-hexyloxy-phenyl group or the like. Examples of a Cl-Cβ phenyl alkyl group include a benzyl group, 1-phenethyl group, 2-phenethyl group, 3-phenylpropyl group, 2-phenylpropyl group, 4-phenylbutyl group, 5-phenylpentyl group, 4-phenylpentyl group, group 6-phenylhexyl, 2-methyl-3-phenylpropyl group, 1,1-dimethyl-2-phenylethyl group or the like. A C1-C3 alkyl phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a substituted C1-C6 alkoxy group or unsubstituted with halogen, can be substituted) includes a C 1 -C 6 alkyl group unsubstituted or substituted on the phenyl ring by 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen, examples of which include a benzyl group, 1-phenethyl group, 2-phenethyl group, 3-phenylpropyl group, group 2 phenylpropyl, 4-phenylbutyl group, 5-phenylpentyl group, 4-phenylpentyl group, 6-phenylhexyl group, 2-fluorobenzyl group, 3-fluorobenzyl group, 4-fluorobenzyl group, 2-chlorobenzyl group, 3-chlorobenzyl group, 4-group chlorobenzyl, group 2-bro Mobenzyl, 3-bromobenzyl group, 4-bromobenzyl group, 2-iodobenzyl group, 3-iodobenzyl group, 4-iodobenzyl group, 2-difluorobenzyl group, 3-difluorobenzyl group, 3-difluorobenzyl group 2 group , 4-difluorobenzyl, 2,6-difluoro-benzyl group, 2-dichlorobenzyl group, 3,4-dichlorobenzyl group, 3-dichlorobenzyl group, 2,4-dichlorobenzyl group, group 2, 6 -dichlorobenzyl, 2-fluoro-4-bromobenzyl group, 4-chloro-3-fluorobenzyl group, 2,3,4-trichlorobenzyl group, 3, 4, 5-trifluorobenzyl group, 2,4,6-trichlorobenzyl group 4 -isopropylbenzyl, 4-n-butylbenzyl group, 4-methylbenzyl group, 2-methylbenzyl group, 3-methylbenzyl group, 2, 4-dimethylbenzyl group, 2,3-dimethylbenzyl group, 2, 6-dimethylbenzyl group, 3,5-dimethylbenzyl group, group 2, 5-dimethyl-benzyl, 2,4,6-trimethylbenzyl group, 3,5-ditrifluoromethylbenzyl group, 2, 3, 4, 5, 6-penta-fluorobenzyl group, 4-isopropoxybenzyl group, group 4-n -butoxybenzyl, 4-methoxybenzyl group, 2-methoxybenzyl group, 3-methoxybenzyl group, 2,4-dimethoxybenzyl group, 2,3-dimethoxybenzyl group, 2,6-dimethoxybenzyl group, 3,5-dimethoxybenzyl group, 2.5 group -dimethoxybenzyl, group 2, 4,6-trimethoxybenzyl, 3,5-ditrifluoromethoxybenzyl group, 2-isopropoxybenzyl group, 3-chloro-4-methoxybenzyl group, 2-chloro-4-trifluoromethoxybenzyl group, 3-methyl-4-fluorobenzyl group , 4-bromo-3-trifluoromethylbenzyl group, 2-trifluoromethylbenzyl group, 3-trifluoromethylbenzyl group, 4-trifluoromethylbenzyl group, 2-pentafluoro-ethylbenzyl group, 3-pentafluoroethylbenzyl group, 4-pentafluoroethylbenzyl group, 2-trifluoromethoxybenzyl group, group 3 trifluoromethoxybenzyl, 4-trifluoro-methoxybenzyl group, 2-pentafluoroethoxybenzyl group, 3-pentafluoroethoxybenzyl group, 4-pentaflu group Oroethoxy-benzyl, 2- (2-trifluoromethylphenyl) ethyl group, 2- (3-trifluoromethylphenyl) ethyl group, 2- (4-trifluoromethylphenyl) ethyl group, 2- (2-trifluoromethoxyphenyl) -ethyl group, 2- group (3- (trifluoromethoxyphenyl) ethyl, 2- (4-trifluoromethoxyphenyl) ethyl group, 2- (2-pentafluoroethoxyphenyl) ethyl group, 2- (3-pentafluoro-ethoxyphenyl) ethyl group, 2- (4-pentafluoroethoxy-phenyl) group ethyl, 3- (2-trifluoromethylphenyl) propyl group, 3- (3-trifluoromethylphenyl) propyl group, 3- (4-trifluoromethylphenyl) propyl group, 3- (2-trifluoromethoxyphenyl) propyl group, 3- (3-) group trifluoromethoxy-phenyl) propyl, 3- (4-trifluoromethoxyphenyl) propyl group, 3- (3-pentafluoroethoxyphenyl) propyl group, 3- (4-pentafluoroethoxyphenyl) propyl group, 4- (3-pentafluoro-ethoxyphenyl) butyl group, group 5 - (4-trifluoromethylphenyl) -pentyl, 4- (4-trifluoromethylphenyl) pentyl group, 4- (4-trifluoromethoxyphenyl) pentyl group, 6- (3-trifluoromethylphenyl) hexyl group, 6- (4-trifluoromethylphenyl) hexyl group, group 6- (4-trif luoromethoxy-phenyl) hexyl or the like. A Cl-Cß phenyl alkyl group [wherein, in the phenyl group, at least one selected from the group consisting of a halogen atom, a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted by halogen and a Cl-Cβ alkoxy group substituted or unsubstituted by halogen, can be substituted), a Cl-Cß alkyl group substituted or unsubstituted by halogen and a C1-Cß alkoxy group substituted or unsubstituted with halogen, can be substituted] includes an alkyl phenyl group wherein the alkyl portion is a straight or branched alkyl group containing 1 to 6 carbon atoms [wherein, in the group phenyl, 1 to 5, preferably 1 to 3 groups selected from the group consisting of a halogen atom, a phenyl group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 groups selected from the group consisting of halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), a Cl-Cß alkyl group substituted or unsubstituted with halogen and a group Cl-Cβ alkoxy substituted or unsubstituted with halogen, can be substituted], examples of which include a 4- (4-trifluoromethylphenyl) benzyl group, 4- (4-trifluoromethoxyphenyl) benzyl group, 4- (4-chlorophenyl) group) benzyl, 4- (4-trifluoromethylphenyl) -benzyl group, 4-phenylbenzyl group, 3-phenylbenzyl group, 3,4-diphenylbenzyl group, 3,4,5-triphenylbenzyl group, 4-nitro-3-trifluoromethylbenzyl group 4 -trifluoromethoxy-3-phenylbenzyl or the like, in addition to the Cl-Cβ phenyl alkyl group mentioned above (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted Cl-Cβ alkyl group or not substituted with halogen and a C1-Cβ alkoxy group substituted gone or not replaced with halogen, can be replaced). A piperazinyl group [wherein, in the piperazine ring, at least one Cl-Cβ phenyl alkyl group can be substituted (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a group substituted or unsubstituted Cl-Cβ alkyl with halogen and a substituted or unsubstituted C 1 -C 6 alkoxy group with halogen, can be substituted)] includes a piperazinyl group [wherein, in the piperadine ring, 1 to 3 Cl-Cβ alkyl groups phenyl can be substituted (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and an alkoxy Cl group -Cβ substituted or unsubstituted with halogen, can be substituted)], for example, 1-piperazinyl group, 2-piperazinyl group, group 3, 4-dibenzyl-l-piperazinyl, group 2, 3, 4-tribenzyl-l-piperazinyl, 4-benzyl-l-piperazinyl group, 4- (2-f-ethyl) -1-piperazinyl group, group 4- ( 3-f-enylpropyl) -1- piperazinyl, 4- (4-phenylbutyl) -1-piperazinyl group, 4- (5-f-enylpentyl) -1-piperazinyl group, 4- (6-f-enylhexyl) -1-piperazinyl group , 4- (2-f luorobenzyl) -1-piperazinyl group, 4- (3-f luorobenzyl) -1-piperazinyl group, 4- (4-fluorobenzyl) -l-piperazinyl group, 4- (2-chlorobenzyl) group -1-piperazinyl, 4- (3-chlorobenzyl) -1-piperazinyl group, 4- (4-chlorobenzyl) -l-piperazinyl group, 4- (2,3-dichlorobenzyl) -1-piperazinyl group, group 4- ( 2,4-di-chlorobenzyl) -l-piperazinyl, 4- (3,4-dichlorobenzyl) -1-piperazinyl group, 4- (3,5-dichlorobenzyl) -1-piperazinyl group, group 4- (3,4, 5-tri chlorobenzyl) -1-piperazinyl, 4- (2, 3, 4, 5, 6-pentaf luorobenzyl) -1-piperazinyl group, 4- (2-trifluoromethylbenzyl) -1-piperazinyl group, group 4- (3 -trif luoromethylbenzyl) - 1-piperazinyl, group 4- (4-tr if luoromethylbenzyl) -l-piperazinyl, group 4- (4-methylbenzyl) -1-piperazinyl, 4- (3,4-dimethylbenzyl) -1-piperazinyl group, 4- (2,4,6-trimethylbenzyl) -l-piperazinyl group, 4- (2 -) group pentaf luoroethylbenzyl) -1-piperazinyl, 4- (3-pentafluoroethylbenzyl) -1-piperazinyl group, 4- (4-pentafluoroethylbenzyl) -1-piperazinyl group, 4- (2-trifluoromethoxybenzyl) -1-piperazinyl group, group 4- (3-trifluoromethoxybenzyl) -1-piperazinyl, 4- (4-trifluoromethoxybenzyl) -1-piperazinyl group, 4- (4-methoxybenzyl) -1-piperazinyl group, 4- (3,4-dimethoxybenzyl) -1 group -piperazinyl, 4- (2,4-b-trimethoxybenzyl) -1-piperazinyl group, 4- (2-pentafluoroethoxybenzyl) -1-piperazinyl group, 4- (3-pentafluoroethoxybenzyl) -1-piperazinyl group, group 4- (4- pentafluoroethoxybenzyl) -1-piperazinyl, 4- [2- (4-trifluoromethoxyphenyl) ethyl] -1-piperazinyl group, 4- [3- (4-trifluoromethoxyphenyl) propyl] -1-piperazinyl group, group 4- [ 4- (4-trifluoromethoxyphenyl) butyl] -1-piperazinyl, group 4- [5- (4-trifluoromethoxyphenyl) -pen useful] -1-piperazinyl, 4- [6- (4-trifluoromethoxyphenyl) hexyl] -1-piperazinyl group, 4- [2- (4-trifluoromethylphenyl) ethyl] -1-piperazinyl group, 4- [3- ( 4-trifluoromethylphenyl) propyl] -1-piperazinyl, 4- [4- (4-trifluoromethoxyphenyl) butyl] -1-piperazinyl group, 4- [5- (4-trifluoromethylphenyl) -pentyl] -1-piperazinyl group, group 4 - [6- (4-trifluoromethylphenyl) hexyl] -1-piperazinyl or the like. A piperidyl group [wherein, in the piperidine ring, at least one selected from the group consisting of an amino group (wherein, in the amino group, at least one selected from the group consisting of a phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted] and a alkyl group Cl-Cβ, can be substituted), a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted) and a C1-C6 alkyl group phenyl (wherein, on the phenyl ring, at least one group selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted unsubstituted or substituted by halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), can be substituted] includes a piperidyl group [wherein, in the piperidine ring, 1 to 3 substituents selected from the group consists of an amino group (wherein, in the amino group, 1 or 2 substituents selected from the group consisting of a phenyl group [wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 groups selected from the group consisting of of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted] and a Cl-Cß alkyl group, can be substituted), a phenoxy group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen, can be substituted) and a C 1 -C 6 alkyl group phenyl (wherein, in the phenyl ring, 1 to 5) , preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), can be substituted], eg, a 1-piperidyl group, 2-piperidyl group, 3-piperidyl group, 4-piperidyl group, 2-4-diamino-1-piperidyl group, 2, 4, 6-triamino-l- group piperidyl, 2-amino-1-piperidyl group, 3-amino-1-piperidyl group, 4-amino-1-piperi group dilo, 4-methylamino-1-piperidyl group, 4-ethylamino-1-piperidyl group, 4-n-propylamino-1-piperidyl group, 4-dimethylamino-1-piperidyl group, 4-diethylamino-1-piperidyl group, group 4-di-n-propylamino-1-piperidyl, 4-phenylamino-1-piperidyl group, 4- (N-phenyl-N-methylamino) -1-piperidyl group, 4- (2-fluorophenylamino) -1-piperidyl group , group 4- (3-f luorofenylamino) -1-piperidyl, group 4- (4-f luorofenylamino) -l-piperidyl, 4- (2-chlorophenylamino) -l-piperidyl group, group 4- (3- chlorofenylamino) -1-piperidyl, 4- (4-chlorofenylamino) -1-piperidyl group, 4- (2,3-di chlorofenylamino) -1-piperidyl group, group 4- (2, 4, 6-trif luorof enylamino) -1-piperidyl, 4- (2,4-dichlorophenylamino) -1-piperidyl group, 4- (3,4-dichlorofenylamino) -1-piperidyl group, 4- (3,5-dichlorofenylamino) group -1-piperidyl, 4- (2, 3, 4, 5, 6-pentaf luorofenylamino) -1-piperidyl group, 4- (2-trifluoromethylphenylamino) -l-piperidyl group, 4- (2-methyl-phenylamino) group -1-piperidyl, 4- (2, 3-dimethyl-phenylamino) -1-piperidyl group, 4- (2-trifluoromethylphenylamino) -l-piperidyl group, 4- (2,4,6-trimethyl-phenylamino) -1-piperidyl group, group 4- (4-trif luoromethyl-phenylamino) -1-piperidyl, 4- (2-pentaf-luoroethyl-phenylamino) -1-piperidyl group, 4- (3-pentaf-luoroethyl-phenylamino) -1-piperidyl group, 4- (4-pentafluoroethylphenyl) group. no) -l-piperidyl, 4- (2- trifluoromethoxyphenylamine) -1-piperidyl group, 4- (2-methoxyphenylamino) -1-piperidyl group, 4- (2,3-dimethoxyphenylamino) -l-piperidyl group, 4- (2,4,6-trimethoxy-phenylamino) -1-piperidyl group, 4- [N-methyl-N- (2,4,6-trimethoxyphenylamino)] -1-piperidyl group 4- [N-methyl] -N- (3,4-di-ethyl-phenylamino)] -1-piperidyl, 4- (3-trifluoromethoxy-phenylamino) -1-piperidyl group, 4- (4-trifluoromethoxy-phenylamino) -1-piperidyl group 4 - (2-pentaf luoroethoxy-enylamino) -1-piperidyl, 4- (3-pentaf-luoroethoxy-enylamino) -1-piperidyl group, 4- (4-pentaf-luoroethoxy-enylamino) -1-piperi group dilo, 4-f-enoxy-1-piperidyl group, 2,4-diphenoxy-1-piperidyl group, 2,4,6-triphenoxy-1-piperidyl group, 2- (2-fluorophenoxy) -1-piperidyl group , group 3- (3-f luorofenoxi) -2-piperidyl, group 4- (4-fluoro-enoxy) -3-piperidyl, 2- (2-chloro-enoxy) -4-piperidyl group, group 3- (3- chlorofenoxy) -5-piperidyl, 4- (4-chlorofenoxi) -2-piperidyl group, 5- (2-bromofenoxi) -2-piperidyl group, 6- (3-bromo phenoxy) -3-piperidyl group, 4- (4-bromophenoxy) -1-piperidyl group, 3- (2, 3-dichlorophenoxy) -2-piperidyl group, 4- (3,4-dichloro-enoxy) -3-piperidyl group, group 3- (2, 4-dichloro-enoxy) -4-piperidyl, 2- (3, 4, 5-trichlorofenoxi) -3-piperidyl group, ß- (2, 4, 6-trichlorofenoxi) -2-piperidyl group, group 3- ( 2, 3, 4, 5, 6-pentaf luorofenoxi) -1-piperidyl, 4- (2-methyl-enoxy) -1-piperidyl group, 5- (3-methyl-enoxy) -2-piperidyl group, group 6- (4-methyl-enoxy) -3-piperidyl, 1- (2-ethylf-enoxy) -4-piperidyl group, 2- (3-ethylphenoxy) -1-piperidyl group, 3- (4-ethyl) group enoxi) -2-piperidyl, 4- (4-n-propylphenoxy) -3-piperidyl group, 3- (4-tert-butylphenoxy) -4-piperidyl group, 2- (4-n-butylphenoxy) -3-piperidyl group, group 1- ( 2-trifluoromethylphenoxy) -2-piperidyl, 2- (3-trifluoromethylphenoxy) -1-piperidyl group, 3- (4-trifluoromethylphenoxy) -1-piperidyl group, 1- (2-pentafluoroethylphenoxy) -4-piperidyl group, group I - (3-pentafluoroethylphenoxy) -4-piperidyl, 4- (2,3-dimethylphenoxy) -1-piperidyl group, l- (3,4,5-trimethylphenoxy) -4-piperidyl group, group I- (4-n) -pentylphenoxy) -4-piperidyl, 4- (4-n-hexylphenoxy) -1-piperidyl group, 4- (2-methoxyphenoxy) -l-piperidyl group, 1- (3-methoxyphenoxy) -4-piperidyl group, group 1- (4-methoxyphenoxy) -4-piperidyl, 2- (2-ethoxyphenoxy) -3-piperidyl group, 3- (3-ethoxyphenoxy) -4-piperidyl group, 4- (4-ethoxyphenoxy) -3-piperidyl group , 3- (4-n-propoxyphenoxy) -2-piperidyl group, 2- (4-tert-butoxyphenoxy) -1-piperidyl group, l- (4-n-butoxyphenoxy) -2-piperidyl group, 2- (group 2-trifluoromethoxyphenoxy) -3-piperidyl, 3- (3-trifluoromethoxyphenoxy) - 4-piperidyl, 4- (4-trifluoromethoxyphenoxy) -3-piperidyl group, 3- (2-pentafluoroethoxyphenoxy) -2-piperidyl group, 2- (4-pentafluoroethoxyphenoxy) -1-piperidyl group, group 1- (2, 3) -methoxyphenoxy) -4-piperidyl, 4- (3,4,5-trimethoxyphenoxy) -l-piperidyl group, 4- (4-n-pentyloxyphenoxy) -l-piperidyl group, 4- (4-n-hexyloxyphenoxy) group) -l-piperidyl, 4-benzyl-1-piperidyl group, 2,4-dibenzyl-1-piperidyl group, 2,4,6-tribenzyl-1-piperidyl group, 2- (2-fluorobenzyl) -1-piperidyl group , 3- [2- (3-fluorophenyl) ethyl] -2-piperidyl group, 4- [l- (4-fluorophenyl) ethyl] -3-piperidyl group, 2- [3- (2-chlorophenyl) propyl] group -4-piperidyl, 3- [4- (3-chlorophenyl) butyl] -5-piperidyl group, 4- [5- (4-chlorofenyl) pentyl] -2-piperidyl group, 5- [6- (2 -bromophenyl) hexyl] -2-piperidyl, 6- (3-bromobenzyl) -3-piperidyl group, 4- (4-bromobenzyl) -1-piperidyl group, 3- (2,3-dichlorobenzyl) -2- piperidyl group , 4- (3,4-dichlorobenzyl) -3-piperidyl group, 3- (2,4-dichlorobenzyl) -4-piperidyl group, group 2- (3,4,5-trichlorobenzyl) -3-piperidyl, 6- (2,4,6-trifluorobenzyl) -2-piperidyl group, 3- (2,3,4,5, β-pentaf luorobenzyl) -1-piperidyl, 4- (2-methylbenzyl) -1-piperidyl group, 5- [2- (3-methylphenyl) ethyl] -2-piperidyl group, 6- [3- (4-methyl) group enyl) propyl] -3-piperidyl, 1- [4- (2-ethylf-enyl) butyl] -4-piperidyl group, 2- [5- (3-ethylphenyl) pentyl] -1-piperidyl group, group 3- [ 6- (4-ethylf-enyl) hexyl] -2-piperidyl, 4- (4-n-propylbenzyl) -3-piperidyl group, 3- (4-tert-butylbenzyl) -4-piperidyl group, 2- (4-group -n-butylbenzyl) -3-piperidyl, 1- (2-trifluoromethylbenzyl) -2-piperidyl group, 2- (3-trifluoromethylbenzyl) -1-piperidyl group, 3- (4-trifluoromethylbenzyl) -1- group piperidyl, l- (2-pentaf luoroethylbenzyl) -4-piperidyl group, 1- (3-pentafluoroethylbenzyl) -4-piperidyl group, 4- (2,3-dimethylbenzyl) -1-piperidyl group, group 1- (3 , 4,5-trimethylbenzyl) -4-piperidyl, 1- (4-n-pentylbenzyl) -4-piperidyl group, 4- (4-n-hexylbenzyl) -1-piperidyl group, g 4- (2-methoxybenzyl) -1-piperidyl group, l- [2- (3-methoxy-enyl) ethyl] -4-piperidyl group, l- [l- (4-methoxy-enyl) -ethyl] -4-piperidyl group , 2- [3- (2-ethoxyl-enyl) -propyl] -3-piperidyl group, 3- [4- (3-ethoxyphenyl) butyl] -4-piperidyl group, 4- [5- (4-ethoxy-enyl) group] pentyl] -3-piperidyl, 3- [6- (4-n-propoxyphenyl) hexyl] -2-piperidyl group, 2- (4-tert-butox: L-benzyl) -l-piperidyl group, group I- (4- n-butoxybenzyl) -2-piperidyl, 2- (2-trifluoromethoxybenzyl) -3-piperidyl group, 3- (3-trifluoromethoxybenzyl) -4-piperidyl group, 4- (4-trifluoromethoxybenzyl) -3-piperidyl group , 3- (2-pentafluoroethoxybenzyl) -2-piperidyl group, 2- (4-pentafluoroethoxybenzyl) -l-piperidyl group, 1- (2,3-dimethoxybenzyl) -4-piperidyl group, group 4- (3,4 , 5-trimethoxybenzyl) -l-piperidyl, 4- (4-n-pentyloxybenzyl) -l-piperidyl group, 4- (4-n-hexyloxybenzyl) -l-piperidyl group, 4-benzyl-3-phenoxy group -piperidyl, 4-phenoxy-2-methylamino-1-piperidyl group or the like. A Cl-Cß alkyl group substituted with Cl-Cβ alkoxy Cl-Cβ alkoxy includes an alkoxyalkoxyalkyl group having a straight or branched alkoxy group containing 1 to 6 carbon atoms in the alkoxy part and a straight or branched alkyl group containing 1 to 6 carbon atoms. up to 6 carbon atoms in the alkyl part, for example, a methoxymethoxymethyl group, 2- (methoxymethoxy) ethyl group, 1- (2-methoxyethoxy) ethyl group, 1- (methoxymethoxy) ethyl group, 2- (3-propoxy) propoxyethyl group, group 3- (2- ethoxy isopropoxy) propyl, 4- (4-butoxybutoxy) butyl group, 5- (5-pentyloxypentyloxy) pentyl group, 6- (6-hexyloxyhexyloxy) hexyl group, 1-l-dimethyl-2- (ethoxymethoxy) ethyl group 2 -methyl-3- (methoxyethoxy) -propyl or 3- (propoxymethoxy) propyl group or the like. A C 1 -C 6 alkyl group substituted with C 1 -C 6 alkoxy thienyl (wherein, in the thiophene ring, at least one halogen atom can be substituted) includes a thienylalkoxyalkyl group having a straight or branched alkoxy group containing 1 to 6 atoms of carbon in the alkoxy part and a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl part (wherein, in the thiophene ring, 1 to 3 halogen atoms can be substituted as a substituent group), eg, a 2-thienylmethoxymethyl group, 3-thienylmethoxymethyl group, 2- (2- (2-thienyl) ethoxy) ethyl group, 3- (3- (2-thienyl) propoxy) propyl group, 4- (4- group) (2-thienyl) butoxy) butyl, 4- (4- (3-thienyl) butoxy) butyl group, 5- (5- (2-thienyl) pentyloxy) pentyl group, 5- (5- (3-thienyl)) pentyloxy) pentyl, 6- (6- (2-thienyl) hexyloxy) hexyl group, 6- (6- (3-thienyl) hexyloxy) hexyl group, (5-chloro-2-thienylmethoxy) methyl group, (5-) chloro-3-thienyl methoxy) methyl, 2- (2- (4-bromo-2-thienyl) ethoxy) ethyl group, 3- (3- (3-f luoro-2-thienyl) propoxy) propyl group, 4- (4- (5-iodo- 2-thienyl) butoxy) butyl, 4- (4- (4-chloro-3-thienyl) butoxy) butyl group, 5- (5- (3-chloro-2-thienyl) pentyloxy) pentyl group 5- ( (2-Chloro-3-thienyl) methoxy) pentyl, 6- (2- (3-chloro-2-thienyl) ethoxy) hexyl group, 6- (6- (5-chloro-3-thienyl) hexyloxy) hexyl group , group (2- (4,5-dichloro-2-thienyl) ethoxy) methyl, ((2, 4, 5-trichloro-3-thienyl) methoxy) methyl or the like. A C1-C6 alkyl group substituted with C2-C6 alkenyloxy phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C3 alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted by halogen can be substituted) is a group consisting of a phenyl group unsubstituted or substituted by 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a group straight or branched alkyl substituted or unsubstituted with halogen containing 1 to 6 halogen carbon atoms and a straight or branched alkoxy group substituted or unsubstituted with halogen containing 1 to 6 carbon atoms and an alkenyl group containing 2 to 6 atoms carbon and having at least 1 to 3 double bonds. The C2-C6 alkenyloxy phenyl group includes both trans and cis forms. The group such as C1-C6 alkenyloxy C2-C6 alkenyloxy phenyl includes a (2-f-enylvinyloxy) methyl group, (3-phenyl-2-propenyloxy) methyl group, 2- (4-f-enyl-2-butenyloxy) ethyl group , 1- (4-f-enyl-3-butenyloxy) ethyl group, 3- (4-f-enyl-1,3-butadienyloxy) propyl group, 4- (5-phenyl-1,3,5-hexatrienyloxy) butyl group , 5- (3- (2-fluorophenyl) -2-propenyloxy) pentyl group, 6- (3- (3-fluorophenyl) -2-propenyloxy) hexyl group, (3- (4-fluorophenyl) -2 group -propenyloxy) methyl, 2- (3- (2,3-difluorofenyl) -2-propenyloxy) ethyl group, 3- (3- (2, 3, 4, 5, 6-pentaf luorofenyl) -2 group -propenyloxy) propyl, 4- (3- (2,4-difluorofenyl) -2-propenyloxy) butyl group, 5- (3- (3,4-difluorofenyl) -2-propenyloxy) pentyl group 6- (3- (3, 5-difluorophenyl) -2-propenyloxy) hexyl, group (3- (2-chlorophenyl) -2-propenyloxy) ethyl, gj_upo 2- (3- (3-chlorophenyl) -2-propenyloxy ) ethyl, 3- (3- (4-chloro-enyl) -2- propenyloxy) propyl group, 4- (3- (2,3-di-chloro-phenyl) group) -2-propenyloxy) butyl, 5- (3- (2,4-dichlorophenyl) -2-propenyloxy) pentyl group, 6- (3- (3,4-di chlorofenyl) -2-propenyloxy) hex Ao group, group (3- (3,5-dichlorofenyl) -2-propenyloxy) methyl, 2- (3- (2-bromo phenyl) -2-propenyloxy) ethyl group, 3- (3- (3-bromophenyl) group) -2-propenyloxy) propyl, 4- (3- (4-bromofenyl) -2-propenyloxy) butyl group, 5- (3- (2-methylphenyl) -2-propenyloxy) pentyl group, group β- (3 - (3-methylphenyl) -2-propenyloxy) hexyl, (3- (4-methylphenyl) -2-propenyloxy) methyl group, 2- (3- (2-trifluoromethylphenyl) -2 -propenyloxy) ethyl group , 3- (3- (2-fluoro-4-bromophenyl) -2-propenyloxy) propyl group, 4- (3- (4-chloro-3-f luorofenyl) -2-propenyloxy) butyl group, group 5- (3- (2,3,4-trichlorophenyl) -2-propenyloxy) pentyl, 6- (3- (2, 4, β-trichlorophenyl) -2-propenyloxy) hexyl group, (3- (4-isopropylphenyl)) group -2-propenyloxy) methyl, 2- (3 ((4-n-butylphenyl) -2-propenyloxy) ethyl group, l- (3- (2,4-dimethylphenyl) -2-propenyloxy) ethyl group 3 - (3 ((2,3-dimethylphenyl) -2-propenyloxy) propyl, ((2,6-dimethylphenyl) -2-propenyloxy) methyl group, 5- (3- (3,5-dimethylphenyl) group) -2-propen iloxy) pentyl, 6- (3- (2,5-dimethylphenyl) -2-propenyloxy) hexyl group, (3- (2,4,6-trimethylphenyl) -2-propenyloxy) methyl group (3- (3, 5-ditrif luoromethylphenyl) -2-propenyloxy) methyl, (3- (4-n-butoxyphenyl) -2-propenyloxy) methyl group, (3- (2,4-dimethoxyphenyl) -2-propenyloxy group ) methyl, group (3- (2,3-dimethoxyphenyl) -2-propenyloxy) methyl, group (3- (2,6-dimethoxyphenyl) -2-propenyloxy) methyl, group (3- (3,5-dimethoxy-enyl) ) -2-propenyloxy) methyl, (3- (2,5-dimethoxy-enyl) -2-propenylbxy) methyl group, (3- (3,5-ditrif luoromethoxy-enyl) -2-propenyloxy) methyl group (3) - (3-chloro-4-methoxy-enyl) -2-propenyloxy) methyl, group (3- (2-chloro-4-trif-loromethoxyphenyl) -2-propenyloxy) methyl, group (3- (3-methyl-4) Fluorofenyl) -2-propenyloxy) methyl, (3- (4-bromo-3-trifluoromethylphenyl) -2-propenyloxy) methyl group, (3- (3-trifluoromethylphenyl) -2-propenyloxy) methyl group, Group (3- (4-trif luoromethyl-enyl) -2-propenyloxy) methyl, group (3- (2-trif luoromethoxy-enyl) ) -2-propenyloxy) methyl, group (3- (3-trifluoromethoxyphenyl) -2 ~ propenyloxy) methyl, group (3- (4-trifluoromethoxyphenyl) -2-propenyloxy) methyl, group (3- (2-methoxyphenyl) ) -2-propenyloxy) methyl, (3- (3-methoxy-f-enyl) -2-propenyloxy) methyl group, (3- (4-methoxy-enyl) -2-propenyloxy) methyl group, (3- (3, 4 -dimet oxyphenyl) -2-propenyloxy) methyl, group (3- (3,5-dimethoxy-enyl) -2-propenyloxy) methyl, group (4- (4-chlorophenyl) -2-butenyloxy) methyl, group (4 - (4-chlorofenyl) -3-butenyloxy) methyl, group (5- (4-chlorophenyl) -2-pentenyloxy) ethyl, group (5- (4-chlorophenyl) -4-pentenyloxy) methyl, group (5- (4-chlorophenyl) -3-pentenyloxy) methyl, group (6- (4-chlorophenyl) -5-hexenyloxy) methyl, group (6- (4-chlorophenyl) -4-hexenyloxy) methyl, group (6- (4-chlorophenyl) -3-hexenyloxy) methyl, (6- (4-chlorofenyl) -3-hexenyloxy) methyl group or the like. A Cl-Cß alkyl group substituted with Cl-Cβ quinolyl alkoxy includes a quinolyl-alkoxyalkyl group having a straight or branched alkoxy group containing 1 to 6 carbon atoms in the alkoxy part and a straight or branched alkyl group containing 1 to 6 atoms of carbon in the alkyl part, for example, a group (2-, 3-, 4-, 5-, 6-, 7- or 8-) quinolylmethoxymethyl, group 2- (2- ((2-, 3-, 4-, 5-, 6-, 7- or 8-) quinolyl) ethoxy) ethyl, group 3- (3- ((2-, 3-, 4-, 5-, 6-, 7- or 8-) quinolyl) propoxy) propyl, group 4- (4- ((2-, 3-, 4-, 5-, 6-, 7- or 8-) -quinolyl) -butoxy) butyl, group 5- (5- ( (2-, 3-, 4-, 5-, ß-, 7- or 8-) quinolyl) -pentyloxy) pentyl, group 6- (6- ((2-, 3-, 4-, 5-6 -, 7- or 8-) -quinolyl) hexyloxy) hexyl or the like. A Cl-Cß alkyl group substituted with Cl-Cβ piperidylcarbonyl alkoxy includes a piperidylcarbonylalkoxyalkyl group having a straight or branched alkoxy group containing 1 to 6 carbon atoms in the alkoxy part and a straight or branched alkyl group containing 1 to 6 atoms of carbon in the alkyl part, for example, (1-, 2- or 3-) piperidylcarbonylmethoxymethyl group, 2- (2 - ((l-, 2- or 3-) piperidylcarbonyl) -ethoxy) ethyl group, group 3 (3 - ((1-, 2- or 3-) piperidylcarbonyl) propoxy) propyl, 4- (4 - ((1-, 2- or 3-) -piperidylcarbonyl) butoxy) butyl group 5- ( 5 - ((1-, 2- or 3-) piperidylcarbonyl) pentyloxy) pentyl, 6- (6 - ((1-, 2- or 3-) -piperidylcarbonyl) -hexyloxy) hexyl group or the like. A C1-C6 alkyl phenyl group [wherein, on the phenyl ring, at least one phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl Cl-Cß group) substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen is substituted) is substituted] includes a phenylalkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl part [ wherein, on the phenyl ring, 1 to 3 phenyl groups (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a straight C 1 -C 6 alkyl group or branched substituted or unsubstituted with halogen and a straight or branched C1-C6 alkoxy group substituted or unsubstituted with halogen are substituted) are substituted, eg, a 2- (2-fluorophenyl) benzyl group, group 3- (3- fluorophenyl) benzyl or, 4- (4-fluorophenyl) benzyl group, 2- (2-chlorophenyl) benzyl group, 3- (3-chlorophenyl) benzyl group, 4- (4-chlorophenyl) benzyl group, 2- (2-bromophenyl) group benzyl, 3- (3-bromophenylbenzyl) group, 4- (4-bromophenyl) benzyl group, 2- (2-iodophenyl) benzyl group, 3- (3-iodophenyl) benzyl group, 4- (4-iodophenyl) benzyl group, 4- (2,3-difluorophenyl) benzyl group, 3- (3,4-difluorophenyl) benzyl group, 2- (3,5-dofluorophenyl) benzyl group, 4- (2,4-difluorophenyl) benzyl group 3 - (2,6-difluorophenyl) benzyl, 2- (2,3-dichlorophenyl) benzyl group, 4- (3,4-dichlorophenyl) benzyl group, 3- (3,5-dichlorophenyl) benzyl group 2- ( 2,4-dichlorophenyl) benzyl, 4- (2,6-dichlorophenyl) benzyl group, 3- (2-fluoro-4-bromophenyl) benzyl group 2- (4-chloro-3-fluorophenyl) benzyl group 4 - (2,3,4-trichlorophenyl) benzyl, 3- (3,4,5-trifluorophenyl) benzyl group, 2- (2,4,6-trichlorophenyl) benzyl group, 4- (4-isopropylphenyl) benzyl group, 3- (4-n-butylphenyl) benzyl group 2- (4-methylphenyl) benzyl, 4- (2-methylphenyl) benzyl group, 3- (3-methylphenyl) benzyl group, 2- (2,4-dimethylphenyl) benzyl group, 4- (2,3-dimethylphenylbenzyl group) , 3- (2,6-dimethylphenyl) benzyl group, 2- (3,5-dimethylphenyl) benzyl group, 4- (2,5-dimethylphenyl) benzyl group 3- (2, 4), 6-trimethylphenyl) benzyl group 2- (3, 5-ditrifluoromethylphenyl) benzyl group, 4- (2,3,4,5, 6-pentafluorophenyl) benzyl group 3- (4-isopropoxyphenyl) benzyl group 2- (4-n-butoxyphenyl) benzyl group, 4- (4-methoxyphenyl) benzyl group 3- (2-methoxyphenyl) benzyl group 2- (3-methoxyphenyl) benzyl group, 4- (2, 4-dimethoxyphenyl) benzyl , 3- (2,3-dimethoxyphenyl) benzyl group, 2- (2,6-dimethoxyphenyl) benzyl group, 2- (3,5-dimethoxyphenyl) benzyl group, 4- (2,5-dimethoxyphenyl) benzyl group 3- (2,4, 6-trimethoxyphenyl) benzyl group 2- (3, 5-ditrifluorometoxifenil) benzyl group, 4- (2-isopropoxyphenyl) benzyl group 3- (3-chloro-4-methoxyphenyl) benzyl group 2- (2-Chloro-4-trifluoromethoxyphenyl) benzyl, 4- (3-methyl-4-fluorophenyl) benzyl group, 3- (4-bromo-3-trifluoromethylphenyl) benzyl group, 4- (2-trifluoromethylphenyl) benzyl group , 3- (3-trifluoromethylphenyl) benzyl group, 4- (4-trifluoromethylphenyl) benzyl group, 2- (2-pentafluoroethylphenyl) benzyl group, 3- (3-pentafluoroethylphenyl) group benzyl, group 2- (4-pentafluoroetilfenil) benzyl group, 4- (2-trifluoromethoxyphenyl) benzyl group 3- (3-trifluoromethoxyphenyl) benzyl group, 4- (4-trifluoromethoxyphenyl) benzyl group, 4- (2-pentaf luoroetoxif enyl) benzyl, 3- (3-pentaf luoroethoxy-enyl) benzyl group, 2- (4-pentaf luoroethoxyphenyl) benzyl group 2- (4- (2-trif luoromethylphenyl) phenyl) ethyl group 2- (3 - (3-trifluoromethylphenyl) phenyl) ethyl, 2- (2- (4-trifluoromethylphenyl) phenyl) ethyl group, 2- (4- (2-trifluoromethoxyphenyl) phenyl) ethyl group 2- ( 3- (3-trifluoromethoxyphenyl) phenyl) ethyl, 2- (2- (4-trifluoromethoxyphenyl) phenyl) ethyl group, 2- (4- (2-pentaf luoroethoxyphenyl) phenyl) ethyl group 2- (3- (3-pentaf luoroethoxyphenyl) phenyl) ethyl, 2- (2- (4-pentaf luoroethoxyphenyl) phenyl) ethyl group, 3- (4- (2-trifluoromethylphenyl) phenyl) propyl group 3 - (3- (3-trifluoromethylphenyl) phenyl) propyl, 3- (2- (4-trifluoromethylphenyl) phenyl) propyl group, 3- (4- (2-trifluoromethoxyphenyl) phenyl) pro group pilo, 3- (3- (3-trifluoromethoxyphenyl) phenyl) propyl group, 3- (2- (4-trifluoromethoxyphenyl) phenyl) propyl group, 3- (4- (3-pentaf luoroethoxy) enyl) phenyl group ) propyl, 3- (3- (4-pentaf luoroethoxyphenyl) phenyl) propyl group, 4- (2- (3-pentaf luoroethoxyphenyl) phenyl) butyl group, 5- (4- (4-trif luoromethylphenyl) group) phenyl) pentyl, 4- (3- (4-trifluoromethylphenyl) phenyl) group, 4- (2- (4-trifluoromethoxyphenyl) phenyl), group β- (4- (3-trif luoromethylphenyl) ) phenyl) hexyl, 6- (3- (4-trifluoromethylphenyl) phenyl) hexyl group, 6- (2- (4-trifluoromethylphenyl) phenyl) hexyl group, 2,4-di (4-trifluoromethylphenyl) benzyl group, 2,4,6-tri (4-trifluoromethoxyphenyl) benzyl group or the like. A C 1 -C 6 alkyl benzoyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen and a substituted C 1 -C 6 alkoxy group or unsubstituted with halogen can be substituted) is a C 1 -C 6 alkyl benzoyl group unsubstituted or substituted on the phenyl ring, the group consisting of 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a straight or branched C 1 -C 6 alkyl group substituted or unsubstituted with halogen and a straight or branched C 1 -C 6 alkoxy group substituted or unsubstituted with halogen, examples of which include a benzoylmethyl group, 1-benzoylethyl group, 2-benzoylethyl group, 3-benzoylpropyl group, 2-benzoylpropyl group, 4-benzoylbutyl group, 5-benzoilpentilo group, 4-benzoilpentilo, the 6-benzoilhexilo group, 2-fluorobenzoilmetilo group, 3-fluorobenzoilmetilo, group 4-fluorobenzoilmetilo-2 clorobenzoilmetilo, group, 3-clorobenzoilmetilo group, 4-clorobenzoilmetilo group, 2-bromobenzoylmethyl group, 3-bromobenzoylmethyl group, 4-bromobenzoylmethyl group, 2-yodobenzoilmetilo group, 3-yodobenzoilmetilo group, 4-yodobenzoilmetilo, group 2,3-difluorobenzoylmethyl, group 3, 4-difluorobenzoylmethyl, 3,5-difluorobenzoylmethyl group, 2,4-difluorobenzylmethyl group, 2,6-difluorobenzoylmethyl group, 2,3-dichlorobenzoylmethyl group, 3,4-dichlorobenzoylmethyl group, 3,5-dichlorobenzoylmethyl group, group 2, 4-dichlorobenzoylmethyl, group 2, ß-dichlorobenzoylmethyl, 2-fluoro-4-bromobenzoylmethyl group, 4-chloro-3-fluorobenzoylmethyl group, 2,3,4-trichlorobenzoylmethyl group, 3, 4, 5-trifluorobenzoylmethyl group, group 2, 4,6-trichlorobenzoylmethyl, 4-isopropylbenzoylmethyl group, 4-n-butylbenzoylmethyl group, 4-methylbenzoylmethyl group, 2-methylbenzoylmethyl group, 3-methylbenzoylmethyl group, 2,4-dimethylbenzoylmethyl group, 2,3-dimethylbenzoylmethyl group, group 2, 6-dimetilbenzoilmetilo group, 3,5-dimetilbenzoilmetilo group, 2,5-dimetilbenzoilmetilo, 2,4, 6-trimetilbenzoilmetilo group, 3,5-ditrifluorometilbenzoilmetilo, group 2, 3,4,5, 6-pentafluorobenzoilmetilo group, 4- isopropoxybenzoylmethyl, 4-n-butoxybenzoylmethyl group, 4-methoxybenzoylmethyl group, 2-met group Oxybenzoylmethyl, 3-methoxybenzoylmethyl group, 2,4-dimethoxybenzoylmethyl group, 2,3-dimethoxybenzoylmethyl group, 2, 6-dimethoxybenzoylmethyl group, 3,5-dimethoxybenzoylmethyl group, 2,5-dimethoxybenzoylmethyl group, 2,4,6-trimethoxybenzoylmethyl group , 3,5-ditrifluoromethoxybenzoylmethyl group, 2-isopropoxybenzoylmethyl group, 3-chloro-4-methoxybenzoylmethyl group, 2-chloro-4-trifluoromethoxybenzoylmethyl group, 3-methyl-4-fluorobenzoylmethyl group, 4-bromo-3-trifluoromethylbenzoylmethyl group 2-trifluorometilbenzoilmetilo, group 3- trifluorometilbenzoilmetilo group, 4-trifluorometilbenzoilmetilo group, 2-pentafluo oetilbenzoilmetilo group, 3-pentafluoroetilbenzoilmetilo group, 4-pentafluoroetilbenzoilmetilo group, 2-trifluorometoxibenzoilmetilo group, 3-trifluorometoxibenzoilmetilo group, 4-trifluorometoxibenzoilmetilo group, 2-pentafluoroetoxibenzoilmetilo, 3-pentafluoroethoxybenzoylmethyl group, 4-pentafluoroethoxybenzoylmethyl group, 2- (2-trifluoromethylbenzoyl) ethyl group, 2- (3-tr) group ifluorometilbenzoil) ethyl group, 2- (4-trifluoromethylbenzoyl) ethyl group, 2- (2-trifluoro ethoxybenzoyl) ethyl group, 2- (3-trifluoromethoxybenzoyl) ethyl group, 2- (4-trifluoromethoxybenzoyl) ethyl group, 2- (2 -pentafluoroetoxibenzoil) ethyl group, 2- (3-pentafluoroetoxibenzoil) ethyl group, 2- (4-pentafluoroetoxibenzoil) ethyl, (2-trifluoromethylbenzoyl) 3- group propyl group, 3- (3-trifluoromethylbenzoyl) propyl group, 3- (4 Trifluoromethylbenzoyl) propyl, 3- (2-trifluoromethoxybenzoyl) propyl group, group 3- (3-trifluoromethoxybenzoyl) propyl group, 3- (4- trifluoromethoxybenzoyl) propyl group, 3- (3-pentafluoroetoxibenzoil) propyl group, 3- (4 -pentafluoroethoxybenzoyl) propyl, 4- (3-pentafluoroethoxybenzoyl) butyl group, 5- (4-trifluoromethylbenzoyl) pentyl group, 4- (4-trifluoromethylbenzoyl) pentyl group, 4- (4-trifluoro-ethoxybenzoyl) pentyl group 6- ( 3-trifluoromethylbenzoyl) hexyl, β- (4-trifluoromethylbenzoyl) hexyl group, 6- (4-trifluoromethoxybenzoyl) hexyl group or the like. An amino group which can be substituted by at least one selected from the group consisting of a Cl-Cß alkyl group, a Cl-Cβ alkoxycarbonyl group and a Cl-Cβ phenyl alkyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group Cl-Cβ substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a C 1-7 alkoxy group Cβ substituted or unsubstituted with halogen can be substituted] includes an amino group which can be substituted by 1 or 2 substituents selected from the group consisting of a straight or branched alkyl group containing 1 to 6 carbon atoms as described above or then, a straight or branched alkoxycarbonyl group containing 1 to 6 carbon atoms, and a phenylalkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl part [wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a phenyl group (wherein, in the phenyl group, 1 to 5, preferably 1 to 3 substituent s selected from the group consisting of a halogen atom, a straight or branched C1-C6 alkyl group substituted or unsubstituted with halogen and a straight or branched C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted), an atom of halogen, a straight or branched C1-C6 alkyl group substituted or unsubstituted with halogen and a straight or branched C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted], for example, an amino group, tert-butoxycarbonylamino group , methylamino group, benzylamino group, (4-trifluoromethoxybenzyl) amino group, (4-trifluoromethylbenzyl) amino group, (4-chlorobenzyl) amino group, (4- (4-trifluoromethoxyphenyl) benzyl) amino group (4- (4 -trifluoromethylphenyl) benzyl) amino, group (4- (4-chlorophenyl) benzyl) amino, N-methyl-N-benzylamino group, N-methyl-N- (4-trifluoromethoxybenzyl) amino group, N-methyl-N- group (4- trifluoromethylbenzyl) amino, N-methyl-N- (4-chlorobenzyl) amino group N-methyl-N- (4- (4-trifluoromethoxyphenyl) benzyl) amino, N-methyl-N- (4- (4-trifluoromethylphenyl) benzyl) amino group, N-methyl-N- (4- (4- chlorophenyl) benzyl) amino, N-methoxycarbonyl-N-benzylamino group, N-ethoxycarbonyl-N- (4-trifluoromethoxybenzyl) amino group, N-propoxycarbonyl-N- (4-trifluoromethylbenzyl) amino group, Nn-butoxycarbonyl-N- group (4-chlorobenzyl) amino, Nn-pentyloxycarbonyl-N- (4- (4-trifluoromethoxyphenyl) benzyl) amino group, N-hexyloxycarbonyl-N- (4- (4-trifluoromethylphenyl) benzyl) amino group, N-ethoxycarbonyl- group N- (4- (4-chlorophenyl) benzyl) amino, N, N-dimethylamino group, N-methyl-N-ethylamino group or the like. A C1-C6 amino alkyl group which can be substituted by at least one selected from the group consisting of a C1-C6 alkyl group and a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) include an aminoalkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl part, which can be substituted by 1 or 2 substituents selected from the group consisting of a straight or branched alkyl group containing 1 to 6 carbon atoms and a phenyl group (wherein, in the ring phenyl, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a straight or branched C1-C6 alkyl group substituted or unsubstituted with halogen and an alkali group straight or branched oxy Cl-Cβ substituted or unsubstituted with halogen can be substituted), for example, an aminomethyl group, 2-aminoethyl group, 1-aminoethyl group, 3-aminopropyl group, 4-aminobutyl group, 5-aminopentyl group, ß-aminohexyl group, 2-methyl-3-aminopropyl group, 1,1-dimethyl-2-aminoethyl group, ethylaminomethyl group, 1- (propylamino) ethyl group, 2- (methylamino) ethyl group, 3- (isopropylamino) propyl group, 4- (n-butylamino) butyl group 5- (n-pentylamino) pentyl, 6- (n-hexylamino) hexyl group, dimethylaminomethyl group, (N-ethyl-N-propylamino) methyl group, 2- (N-methyl-Nn-hexylamino) ethyl group, phenylaminomethyl group , group 1- (phenylamino) ethyl, group 2- (4-chloroanilino) ethyl, group 2- (4-trifluoromethoxyanilino) ethyl, group 2- (4-trifluoromethylanilino) ethyl, group 3- (4-fluoroanilino) propyl, group 4- (3,4-difluoroanilino) butyl, 5- (3,4,6-trifluoroanilino) pentyl group, 6- (4-methylanilino) hexyl group, (3-methoxyanilino) methyl group, group (2,3,4 trimethoxyanilino) methyl, (3,4-dimethylanilino) methyl group, (2,4,6-trimethylanilino) methyl group, (N-ethyl-N- (3,4-dimethoxyanilino)) methyl group, group 2- (N -methyl-n- (4-chloroanilino)) ethyl, 2- (N-methyl-N- (4-trifluoromethoxyanilino)) ethyl group, 2- (N-methyl-N-) group (4-trifluoromethylanilino)) ethyl or the like. A C2-C6 alkenyl benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a substituted Cl-Cß alkoxy group or unsubstituted with halogen can be substituted] includes a benzofuryl alkenyl group having a straight or branched alkenyl group containing 2 to 6 carbon atoms in the alkenyl part and having 1 to 3 double bonds and including both trans and cis forms [ wherein, in the benzofuran ring, 1 to 3 substituents selected from the group consisting of a halogen atom, a straight or branched alkyl group Cl-Cβ substituted or unsubstituted with halogen and a straight or branched alkoxy group Cl-Cβ substituted or not substituted by halogen can be substituted], for example, a 2- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) vinyl group, group 3- ((2-, 3- , 4-, 5-, 6- or 7-) benzofuryl) -2-2-propenyl, group or 3- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) -2-methyl-2-propenyl, group 4- ((2-, 3-, 4-, 5- , 6- or 7-) benzofuryl) -2-butenyl, group 4- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl-3-butenyl, group 4- ((2- , 3-, 4-, 5-, 6- or 7-) benzofuryl) -1, 3-butadienyl, group 5- ((2-, 3-, 4-, 5-, 6- or 7-) -benzofuryl ) -1, 3, 5-hexatrienyl, group 5- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) -2,4-hexadienyl, group 5- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) -3-pentenyl, group 3- (5- trifluoromethyl- (2-, 3-, 4-, 6- or 7-) benzofuryl) -2 -propenyl, 3- (ß-trifluoromethoxy- (2-, 3-, 4-, 5- or 7-) benzofuryl) 2-propenyl group, 3- (6-trifluoromethyl- (2-, 3-, 4- , 5- or 7-) benzofuryl) -2-propenyl, group 3- (4-chloro- (2-, 3-, 5-, β-, or 1-) benzofuryl) -2-propenyl, group 3- ( 4, 5-dimethoxy- (2-, 3-, 6- or 7-) benzofuryl) -2-propenyl, 3- (3, 4, 5-trimethyl- (2-, 6- or 7-) benzofuryl group) -2-propenyl, 3- (3-methyl-5-methoxy- (2-, 4-, β- or 7-) benzofuryl) -2-propenyl group or the like, which includes a benzofuryl alkenyl group (wherein, in the benzofuran ring, 1 to 3 substituents selected from the group consisting of a halogen atom, a straight or branched C1-Cβ alkyl group substituted or unsubstituted with halogen and a straight or branched alkoxy group Cl-Cβ substituted or unsubstituted with halogen can be substituted] including both trans or cis forms. A piperidyl group [wherein, in the piperidine ring, at least one C2-C6 alkenyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group) substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes a piperidyl group [wherein, in the piperidine ring, 1 to 3 phenylalkenyl groups having an alkenyl group straight or branched containing 2 to 6 carbon atoms in the alkenyl part as described above and having 1 to 3 double bonds and including both trans and cis forms (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a straight or branched alkyl group Cl-Cβ substituted or unsubstituted with halogen and a straight or branched alkoxy group Cl- Cβ substituted or unsubstituted with halogen can be substituted) can be substituted], for example, a (1-, 2-, 3- or 4-) piperidyl group, 1- (3-phenyl-2-propenyl) - ( 2-, 3- or 4-) piperidyl, group I, 3-di (3-phenyl-2-propenyl) - (2-, 4-, 5- or 6-) piperidyl, group 1,2,4-tri (3-phenyl-2-propenyl) - (3-, 5- or 6-) -piperidyl, group l- (3- (4-trifluoromethoxyphenyl) -2-propenyl) - (2-, 3- or 4-) piperidyl, 1- (3- (4-trifluoromethylphenyl) -2-propenyl) - (2-, 3- or 4 -) - piperidyl, 1- (3- (4-chlorophenyl) -2-propenyl) - ( 2-, 3- or 4-) piperidyl, 1- (3- (3,4-dimethoxyphenyl) -2-propenyl) - (2-, 3- or 4-) piperidyl group, group 1- (3- (2 , 4, 6-trimethylphenyl) -2-propenyl) -2 (2-, 3- or 4-) piperidyl or the like. A Cl-Cß alkyl group substituted with ferrocene includes a ferrocenalkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl part, for example, a ferrocemethyl group, 1-ferrocenetyl group, 2-ferrocenetyl group , group 3- ferrocenpropyl, group 2-ferrocenpropyl, group 4-ferrocenbutyl, group 5-ferrocenpentilo, group 4-ferrocenpentilo, group 6-ferrocenhexilo, group 1, l-dimetil-2-ferrocenetilo, group 2-methyl-3-ferrocenpropilo or similar. An indolyl C1-C6 alkyl group (wherein, in the indole ring, at least one halogen atom can be substituted) includes an indolyalkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl part (where, in the indole ring, 1 to 3 halogen atoms can be substituted), for example, group ((1-, 2-, 3-, 4-, 5-, 6- or 7-) indolyl) methyl , group 1 - ((1-, 2-, 3-, 4-, 5-, 6- or 7-) indolyl) ethyl, group 2 - ((l-, 2-, 3-, 4-, 5- , 6- or 7-) indolyl) ethyl, group 3 - ((l-, 2-, 3-, 4-, 5-, 6- or 7-) indolyl) propyl, group 2 - ((1-- 2) -, 3-, 4-, 5-, 6- or 1 ~) indolyl) propyl, group 4 - ((l-, 2-, 3-, 4-, 5-, 6- or 7-) indolyl) butyl , group 5 - ((l-, 2-, 3-, 4-, 5-, 6- or 7-) indolyl) pentyl, group 4 - ((l-, 2-, 3-, 4-, 5- , 6- or 7-) indolyl) pentyl, group ß - ((l-, 2-, 3-, 4-, 5-, 6- or 7-) indolyl) hexyl, group 1, l-dimethyl-2- ((1-, 2-, 3-, 4-, 5-, 6- or 7-) -indolyl) ethyl, group 2-methyl-3- ((1-, 2-, 3-, 4-, 5 -, 6- or 7-) indolyl) propyl or, group (5-chloro- (1-, 2-, 3-, 4-, 6- or 7-) indolyl) methyl, group (5,6-difluoro- (1-, 2-, 3-, 4 - or 7-) indolyl) methyl, group (3, 5, 6-tribromo- (1-, 2-, 4- or 7-) indolyl) methyl or the like. A C2-C6 alkynyl phenyl group includes a phenylalkenyl group having a straight or branched alkynyl group containing 2 to 6 carbon atoms in the alkynyl part, for example, a 2-phenylethynyl group, 3-phenyl-2-propynyl group, 3-phenyl-1-methyl-2-propynyl group, 4-phenyl-2-butynyl group, 4-phenyl-3-butynyl group, 4-phenyl-1-butynyl group, 5-phenyl-2-pentinyl group, group 6-phenyl-2-hexinyl or the like. A Cl-Cß alkyl group substituted with naphthyl (wherein, in the naphthalene ring, at least one Cl-Cβ alkoxy group can be substituted) includes an alkyl group substituted with naphthyl having a straight or branched alkyl group containing 1 to β carbon atoms in the alkyl part (wherein, in the naphthalene ring, 1 to 3 straight or branched alkoxy groups containing 1 to 6 carbon atoms as described above can be substituted), for example, group (1- or 2) -) naphthyl) methyl, group 1 - ((1- or 2-) naphthyl) ethyl, group 2 - ((l- or 2-) naphthyl) ethyl, group 3 - ((l- or 2-) naphthyl) propyl , group 2 - ((l- or 2-) naphthyl) propyl, group 4- ((1- or 2-) naphthyl) butyl, group 5 - ((l- or 2-) naphthyl) pentyl, group 4- ( (l- or 2-) naphthyl) pentyl, group ß - ((l- or 2-) naphthyl) hexyl, group 1, l-dimethyl-2- ((1- or 2-) naphthyl) ethyl, group 2 methyl-3- ((1- or 2-) naphthyl) propyl, group (6-methoxy- (1-, 2-, 3-, 4-, 5-, 7- or 8-) naphthyl) methyl, group (5,6-dimethoxy- (1-, 2-, 3-, 4-, 7- or 8-) -naphthyl) methyl, group (5,6,7-trimethoxy- (1-, 2-, 3-, 4- or 8-) naphthyl) methyl or the like. A benzothiazolyloxy group (wherein, in the benzothiazole ring, at least one selected from the group consisting of a group (b-1) phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], a (b-2) piperadinyl group [wherein, in the piperidine ring, minus one selected from the group consisting of a Cl-Cβ alkyl phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted), a C2-C6 alkenyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a group C1-Cß alkyl substituted or not substituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) and a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group Cl-Cβ substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted], a (b-3) piperidyl group [wherein, in the piperidine ring, at least one selected from the group consisting of an amino group (wherein, at the amino group, at least one selected from the group consisting of a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] and a Cl-Cß alkyl group can be substituted), a phenoxy group (in where, e n the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) and a Cl-Cß alkyl phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cβ alkyl group and a substituted Cl-Cβ alkoxy group or not substituted by halogen can be substituted), a group (b-4) pyrrolyl [wherein, in the pyrrole ring, at least one selected from the group consisting of a Cl-Cß alkyl group and a C1 alkyl group can be substituted] -C6 phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substit uido) can be substituted] and a group (b-5) phenylthio (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted) includes a benzothiazolyloxy group (wherein, in the benzothiazole ring, 1 to 3 substituents selected from the group consisting of a group (b-1) ) phenyl (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or not substituted by halogen can be substituted), a (b-2) piperadinyl group [wherein, in the piperidine ring, 1 to 3 substituents selected from the group consisting of a Cl-Cβ phenyl alkyl group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a C2-C6 alkenyl group phenyl having a straight or branched alkenyl group containing 2 to 6 carbon atoms in the alkenyl part and having 1 to 3 double bonds as described later and including both trans and cis forms (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and an alkoxy Cl group -Cβ substituted or unsubstituted with halogen can be substituted) and a phenyl group as described above (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected of the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted], a group (b-3) ) piperidyl [wherein, in the piperidine ring, 1 to 3 substituents selected from the group consisting of an amino group (wherein, in the amino group, 1 or 2 groups selected from the group consisting of a phenyl group [wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] and 1 or 2 groups selected from the group consisting of Cl-Cβ alkyl groups can be substituted), a phenoxy group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected s of the group consisting of a halogen atom, a substituted or unsubstituted C1-C6 alkyl group with halogen and a substituted or unsubstituted C1-C6 alkoxy group with halogen can be substituted) and a C1-C3 alkyl group phenyl (in where, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted or unsubstituted Cl-Cβ alkoxy group with halogen can be substituted), a (b-4) pyrrolyl group can be constituted as described later [wherein, in the pyrrole ring, 1 to 3 substituents selected from the group consisting of a Cl-Cß alkyl group and a Cl-Cß alkyl phenyl group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] and a group (b-5) phenylthio as described later (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted, for example, a 2-benzothiazolyloxy group, 4-benzothiazolyloxy group, 5-benzothiazolyloxy group, 6-benzothiazolyloxy group, 7- benzothiazolyloxy group, 2- (1-piperadinyl) -4-benzothiazolyloxy group, 2- (4-benzyl-1-piperadinyl) group -4-benzothiazolyloxy, 2- (3,4-dibenzyl-l-piperadinyl) -4-benzothiazolyloxy group, 5- (2, 3, 4-tribenzyl-l-piperadinyl) -2-benzothiazolyloxy group, 4- (4-benzothiazolyloxy) group - (2-phenethyl) -1-piperadinyl) -2-benzothiazolyloxy, 4- (4- (3-phenylpropyl) -1-piperadinyl) -5-benzothiazolyloxy group, 4- (4- (4-phenylbutyl) -1-piperadinyl) -6-benzothiazolyloxy group, 4- (4- (5-phenylpentyl) -1-piperadinyl) -7-benzothiazolyloxy group 2- (4- (6-phenylhexyl) -1-piperadinyl) -4-benzothiazolyloxy, 4- (4- (2-fluorobenzyl) -1-piperadinyl) -2-benzothiazolyloxy group 2- (4- (3- fluorobenzyl) -1-piperadinyl) -4-benzothiazolyloxy, 2- (4- (4-fluorobenzyl) -1-piperadinyl) -5-benzothiazolyloxy group, 2- (4- (2-chlorobenzyl) -1-piperadinyl) - 6-benzothiazolyloxy, 2- (4- (3-chlorobenzyl) -1-piperazinyl) -7-benzothiazolyloxy group, 5- (4- (4-chlorobenzyl) -1-piperadinyl) -4-benzothiazolyloxy group 6- ( 4- (2,3-dichlorobenzyl) -1-piperadinyl) -4-benzothiazolyloxy group 7- (4- (2,4-dichlorobenzyl) -1-piperadinyl) -4-benzothiazolyloxy group 2- (4- (3 , 4-dichlorobenzyl) -1-piperadinyl) -4-benzothiazolyloxy, 4- (4- (3,5-dichlorobenzyl) -1-piperadinyl) -2-benzothiazolyloxy group, 4- (4- (3, 4, 5 -trichlorobenzyl) -1-piperadinyl) -5-benzothiazolyloxy, 4- (4- (2,3,4,5,6-pentafluorobenzyl) -1-piperadinyl) -2-benzothiazolyloxy group 4- (4- (2 -trifluoromethylbenzyl) -1-piperadinyl) -6-benzothiazolyloxy, group 4- (4- (3-trifluoromethyl) Tylbenzyl) -1-piperadinyl) -7-benzothiazolyloxy, 2- (4- (4-trifluoromethylbenzyl) -1-piperadinyl) -4-benzothiazolyloxy group, 5- (4- (4-methylbenzyl) -1-piperadinyl) - 4-benzothiazolyloxy, 6- (4- (3,4-dimethylbenzyl) -1-piperadinyl) -4-benzothiazolyloxy group, 7- (4- (2,4,6-trimethylbenzyl) -1-piperadinyl) -4- group benzothiazolyloxy, 4- (4- (2-pentafluoroethylbenzyl) -1-piperadinyl) -2-benzothiazolyloxy group, 4- (4- (3-pentafluoroethylbenzyl) -1-piperadinyl) -5-benzothiazolyloxy group 4- (4- (4-pentafluoroethylbenzyl) -1-piperadinyl) -β-benzothiazolyloxy, 4- (4- (2-trifluoromethoxybenzyl) -1-piperadinyl) -7-benzothiazolyloxy group, 5- (4- (3-trifluoromethoxybenzyl) -1- group piperadinil) -4-benzothiazolyloxy, 6- (4- (4-trifluoromethoxybenzyl) -1-piperadinyl) -5-benzothiazolyloxy group, 7- (4- (4-methoxybenzyl) -1-piperadinyl) -5-benzothiazolyloxy group 6- (4- (3, 4-dimethoxybenzyl) -1-piperadinyl) -4-benzothiazolyloxy, 7- (4- (2,6-, 6-trimethoxybenzyl) -1-piperadinyl) -4-benzothiazole group iloxy, 5- (4- (2-pentafluoroethoxybenzyl) -1-piperadinyl) -4-benzothiazolyloxy group, 4- (4- (3-pentafluoroethoxybenzyl) -1-piperadinyl) -2-benzothiazolyloxy group 6- (4-) (4-pentafluoroethoxybenzyl) -1-piperadinyl) -4-benzothiazolyloxy, 4- (4- (2- (4-trifluoromethoxyphenyl) ethyl) -1-piperadinyl) -2-benzothiazolyloxy group 4- (4- (3- (4-trifluoromethoxyphenyl) propyl) -1-piperadinyl) -2-benzothiazolyloxy, 4- (4- (4- (4-trifluoromethoxyphenyl) butyl) -1-piperadinyl) -2-benzothiazolyloxy group 4- (4- ( 5- (4-trifluoromethoxyphenyl) pentyl) -1-piperadinyl) -2-benzothiazolyloxy, 4- (4- (4- (4-trifluoromethoxyphenyl) hexyl) -1-piperadinyl) -2-benzothiazolyloxy group 4- (4) - (2- (4-trifluoromethylphenyl) ethyl) -1-piperadinyl) -2-benzothiazolyloxy, 5- (4- (3- (4-trifluoromethylphenyl) propyl) -1-piperadinyl) -2-benzothiazolyloxy group 6- (4- (4- (4-trifluoromethylphenyl) butyl) -1-piperadinyl) -2-benzothiazolyloxy, 7- (4- (5- (4-trifluoromethylphenyl) pentyl) -1-piperadinyl) -2-benzothiazole group Iloxy, 5- (4- (6- (4-trifluoromethylphenyl) hexyl) -1-piperadinyl) -2-benzothiazolyloxy group, 2- (4- (trifluoromethoxyphenoxy-1-piperidyl)) -6-benzothiazolyloxy group 2- (4- (Trifluoromethoxybenzyl-1-piperidyl)) -6-benzothiazolyloxy, 2- (4- (N-ethyl-N- (4-chlorophenyl) amino) -1-piperidyl) -6-benzothiazolyloxy group, 2-phenyl group -5-benzothiazolyloxy, 2- (4-chlorophenyl) -5-benzothiazolyloxy group, 2- (4-trifluoromethoxyphenyl) -6-benzothiazolyloxy group, 2- (3-trifluoromethylphenyl) -5-benzothiazolyloxy group, group 2- (1-) piperidyl) -4-benzothiazolyloxy, 2- (4-benzyl-1-piperidyl) -4-benzothiazolyloxy group, 2- (3,4-dibenzyl-1-piperidyl) -4-benzothiazolyloxy group, group 5- (2, 3 , 4-tribenzyl-1-piperidyl) -2-benzothiazolyloxy, 4- (4- (2-phenethyl) -1-piperidyl) -2-benzothiazolyloxy group, 4- (4- (3-phenylpropyl) -1-piperidyl group (-5-benzothiazolyloxy, 4- (4- (4-phenylbutyl) -1-piperidyl) -6-benzothiazolyloxy group, 4- (4- (5-phenylpentyl) -1- piperidyl) -7-benzothiazolyloxy group 2 - (4- (6-phenylhex) il) -1- piperidyl) -4-benzothiazolyloxy, 4- (4- (2-fluorobenzyl) -1- piperidyl) -2-benzothiazolyloxy group, 2- (4- (3-fluorobenzyl) -1- piperidyl) -4-benzothiazolyloxy group 2- (4- ( 4-fluorobenzyl) -1-piperadinyl) -5-benzothiazolyloxy, 2- (4- (2-chlorobenzyl) -1-piperidyl) -6-benzothiazolyloxy group, 2- (4- (3-chlorobenzyl) -1-piperidyl group ) -7-benzothiazolyloxy, 5- (4- (4-chlorobenzyl) -1-piperidyl) -4-benzothiazolyloxy group, 6- (4- (2,3-dichlorobenzyl-1-piperidyl) -4-benzothiazolyloxy group 7- (4- (2,4-dichlorobenzyl) -1-piperidyl) -4-benzothiazolyloxy, 2- (4- (3,4-dichlorobenzyl) -1-piperidyl) -4-benzothiazolyloxy group 4- (4- (3,5-dichlorobenzyl) -1-piperidyl) -2-benzothiazolyloxy, 4- (4- (3,4,5-trichlorobenzyl) -1-piperidyl) -5-benzothiazolyloxy group 4- (4- (2, 3, 4, 5, 6-pentafluorobenzyl) -1-piperidyl) -2-benzothiazolyloxy, 4- (4- (2-trifluoromethylbenzyl) -1-piperizyl) -6-benzothiazolyloxy group 4- (4- (3-trifluoromethylbenzyl) -1-piperidyl) -7-benzothiazolyloxy, 2- (4- (4-trifluoromethylbenzyl) -1-piperidyl) -4-benzothiazolyloxy group, 5- (4- (4-methylbenzyl) group) -1-piperidyl) -4-benzothiazolyloxy, 6- (4- (3,4-dimethylbenzyl) -1-piperidyl) -4-benzothiazolyloxy group, 7- (4- (2,4,6-trimethylbenzyl) -1- group -piperizil) -4-benzothiazolyloxy, 4- (4- (2-pentafluoroethylbenzyl) -1-piperidyl) -2-benzothiazolyloxy group, 4- (4- (3-pentafluoroethylbenzyl) -1-piperidyl) -5-benzothiazolyloxy group, 4- (4- (4-pentafluoroethylbenzyl) -1- piperidyl) -6-benzothiazolyloxy group 4- (4- (2-trifluoromethoxybenzyl) -1-piperidyl) -7-benzothiazolyloxy group 5- (4- (3 -trifluoromethoxybenzyl) -1-piperidyl) -4-benzot iazolyloxy, ß- (4- (4-trifluoromethoxybenzyl) -1-piperidyl) -5-benzothiazolyloxy group, 7- (4- (4-methoxybenzyl) -1-piperidyl) -5-benzothiazolyloxy group, 6- (4-) group (3,4-dimethoxybenzyl) -1-piperidyl) -4-benzothiazolyloxy, 7- (4- (2,4-, 6-trimethoxybenzyl) -1-piperidyl) -4-benzothiazolyloxy group, 5- (4- (2) group -pentafluoroethoxybenzyl) -1-piperidyl) -4-benzothiazolyloxy, 4- (4- (3-pentafluoroethoxybenzyl) -1-piperidyl) -2-benzothiazolyloxy group, 6- (4- (4-pentafluoroethoxybenzyl-1-piperidyl) - 4-benzothiazolyloxy, 4- (4- (2- (4-trifluo-methoxyphenyl) ethyl) -1-piperidyl) -2-benzothiazolyloxy group, 4- (4- (3- (4-trifluoromethoxyphenyl) propyl) -1-piperidyl group ) -2-benzothiazolyloxy, 4- (4- (4- (4-trifluoromethoxyphenyl) butyl) -1-piperidyl) -2-benzothiazolyloxy group, 4- (4- (5- (4-trifluoromethoxyphenyl) pentyl) -1 group -piperidyl) -2-benzothiazolyloxy, 4- (4- (6- (4-trifluoromethoxyphenyl) hexyl) -1-piperidyl) -2-benzothiazolyloxy group, 4- (4- (2- (4-trifluoromethylphenyl) ethyl) -1-piperidyl) -2-benzothiazolyloxy, 5- (4- (3- (4-trifluoromethylphenyl) propyl) -1-piperidyl) -2-benzothiazolyloxy group, 6- (4- (4- (4-trifluoromethylphenyl) butyl) -1- group piperidyl) -2-benzothiazolyloxy, 7- (4- (5- (4-trifluoromethylphenyl) pentyl) -1-piperidyl) -2-benzothiazolyloxy group, 5- (4- (6- (4-trifluoromethylphenyl) hexyl) - 1-piperidyl) -2- benzothiazolyloxy, 2- (4-phenoxy-1-piperidyl) -4- benzothiazolyloxy group, 2- (3,4-diphenoxy-1-piperidyl) -4- benzothiazolyloxy group, group 5- (2 , 3, 4-triphenoxy-1-piperidyl) -2-benzothiazolyloxy, 4- (4- (2-fluorophenoxy) -1-piperidyl) -2-benzothiazolyloxy group, 2- (4- (3-fluorophenoxy) -1 group -piperizil) -4-benzothiazolyloxy, 2- (4- (4-fluorophenoxy) -1-piperadinyl) -5-benzothiazolyloxy group, 2- (4- (2-chlorophenoxy) -1-piperidyl) -6-benzothiazolyloxy group, 2- (4- (3-chlorophenoxy) -1-piperidyl) -7-benzothiazolyloxy group, 5- (4- (4-chlorophenoxy) -1-piperidyl) -4-benzothiazolyloxy group 6- (4- (2) group , 3-dichlorophenoxy) -1-piperidyl) -4-benzothiazolyloxy group 7- (4- (2,4-dichlorophenoxy) -1-piperidyl) -4-benzothiazolyloxy, 2- (4- (3,4-dichlorophenoxy) -1-piperidyl) -4-benzothiazolyloxy group 4- (4 - (3,5-dichlorophenoxy) -1-piperidyl) -2-benzothiazolyloxy, 4- (4- (3,4,5-trichlorophenoxy) -1-piperidyl) -5-benzothiazolyloxy group 4- (4- ( 2, 3, 4, 5, 6-pentafluorophenoxy) -1-piperidyl) -2-benzothiazolyloxy, 4- (4- (2-trifluoromethylphenoxy) -1-piperidyl) -6-benzothiazolyloxy group, 4- (4- ( 3-trifluoromethylphenoxy) -1-piperidyl) -7-benzothiazolyloxy, 2- (4- (4-trifluoromethylphenoxy) -1-piperidyl) -4-benzothiazolyloxy group, 5- (4- (4-methylphenoxy) -1-piperidyl group ) -4-benzothiazolyloxy, 6- (4- (3,4-dimethylphenoxy) -1-piperidyl) -4-benzothiazolyloxy group, 7- (4- (2,4,6-trimethylphenoxy) -1-piperidyl) - 4-benzothiazolyloxy, 4- (4- (2-pentafluoroethylphenoxy) -1-piperidyl) -2-benzothiazolyloxy group, 4- (4- (3-pentafluoroethylphenoxy) -1-piperidyl) -5-benzothiazolyloxy group 4- ( 4- (4-pentafluoroethylphenoxy) -1-piperidyl) -6-benzothiazolyl i, 4- (4- (2-trifluoromethoxyphenoxy) -1-piperidyl) -7-benzothiazolyloxy group, 5- (4- (3-trifluoromethoxyphenoxy) -1-piperidyl) -4-benzothiazolyloxy group 6- (4- ( 4-trifluoromethoxyphenoxy) -1-piperidyl) -5-benzothiazolyloxy, 7- (4- (4-methoxyphenoxy) -1-piperidyl) -5-benzothiazolyloxy group, 6- (4- (3,4-dimethoxyphenoxy) -1 group -piperidyl) -4-benzothiazolyloxy, 7- (4- (2,4,6-trimethoxyphenoxy) -1-piperidyl) -4-benzothiazolyloxy group, 5- (4- (2-pentafluoroethoxyphenoxy) -1-piperidyl) - 4-benzothiazolyloxy, 4- (4- (3-pentafluoroethoxyphenoxy) -1-piperidyl) -2-benzothiazolyloxy group, 6- (4- (4-pentafluoroethoxyphenoxy) -1-piperidyl) -4-benzothiazolyloxy group 2, 5 , 6-triphenyl-7-benzothiazolyloxy, 2- (4-amino-1-piperidyl) -β-benzothiazolyloxy group, 4- (2,4-diamino-1-piperidyl) -2-benzothiazolyloxy group, group 5- (2 , 4,6-triamino-l-piperidyl) -4-benzothiazolyloxy, 6- (2-amino-1-piperidyl) -5-benzothiazolyloxy group, 7- (3-amino-1-piperidyl) -6-benzothiazolyloxy group, 2- (4-methylamino-lp group iperidyl) -4-benzothiazolyloxy, 2- (4-ethylamino-1-piperidyl) -5-benzothiazolyloxy group, 2- (4-n-propylamino-1-piperidyl) -6-benzothiazolyloxy group, 2- (4-dimethylamino group -l-piperidyl) -7-benzothiazolyloxy, 2- (4-diethylamino-1-piperidyl) -4- benzothiazolyloxy group, 2- (4-di-n-propylamino-1-piperidyl) -5-benzothiazolyloxy group, group 2 - (4-phenylamino-1-piperidyl) -6-benzothiazolyloxy, 2- (4- (N-phenyl-N-methylamino) -1-piperidyl) -7-benzothiazolyloxy group, 2- (4- (2-fluorophenylamino ) -1-piperidyl) -4-benzothiazolyloxy, 2- (4- (3-fluorophenylamino) -1-piperidyl) -5-benzothiazolyloxy group, 2- (4- (4-fluorophenylamino) -1-piperidyl) -6 group -benzothiazolyloxy, 2- (4- (2-chlorophenylamino) -1-piperidyl) -7-benzothiazolyloxy group, 2- (4- (3-chlorophenylamino) -1-piperidyl) -4-benzothiazolyloxy group 2- (4-benzothiazolyloxy) group - (4-chlorophenylamino) -1-piperidyl) -5-benzothiazolyloxy, 2- (4- (2,3-dichlorophenylamino) -1-piperidyl) -6-benzothiazolyloxy group, 2- (4- (2, 4, 6-trifluorophenylamino) -1-piperidyl) -7- benzothiazolyloxy, 2- (4- (2,4-dichlorophenylamino) -1-piperidyl) -4-benzothiazolyloxy group, 2- (4- (3,4-dichlorophenylamino) -1-piperidyl) -6-benzothiazolyloxy group, group 4 - (3,5-dichlorophenylamino) -1-piperidyl) -5-benzothiazolyloxy, 2- (4- (2,3,4,5,6,6-pentafluorophenylamino) -1-piperidyl) -6-benzothiazolyloxy group 2- (4- (2-trifluoromethylphenylamino) -1-piperidyl) -7-benzothiazolyloxy, 2- (4- (2-methylphenylamino) -1-piperidyl) -4-benzothiazolyloxy group, 2- (4- (2, 3-) group dimethylphenylamino) -1-piperidyl) -5-benzothiazolyloxy, 2- (4- (2-trifluoromethylphenylamino) -1-piperidyl) -6-benzothiazolyloxy group, 2- (4- (2, 4, ß-trimethylphenylamino) -1 group -piperidyl) -7-benzothiazolyloxy, 2- (4- (4-trifluoromethylphenylamino) -1-piperidyl) -4-benzothiazolyloxy group, 2- (4- (2-pentafluoroethylphenylamino) -1-piperidyl) -5- benzothiazolyloxy group, 2- (4- (3-pentafluoroethylphenylamino) -1- piperidyl) -5-benzothiazolyloxy group 2- (4- (4-pentafluoroethylphenylamino) -1-piperidyl) -6-benzothiazolyloxy group 2- (4- (2-trifluoromethoxyphenylamino) -1-piperidyl) -7-benzothiazolyloxy, 2- (4- (2-methoxyphenylamino) -1-piperidyl) -4-benzothiazolyloxy group 2- (4- (2 , 3-dimethoxyphenylamino) -1-piperidyl) -5-benzothiazolyloxy, 2- (4- (2,4,6-trimethoxyphenylamino) -1-piperidyl) -6-benzothiazolyloxy group, 2- (4- (N-methyl) group -N- (2, 4,6-tri-ethoxyphenylamino)) -1-piperidyl) -7-benzothiazolyloxy, 2- (4- (N-methyl-N- (3,4-dimethylphenylamino)) -1-piperidyl group) -4-benzothiazolyloxy, 2- (4- (3-trifluoromethoxyphenylamino) -1-piperidyl) -5-benzothiazolyloxy group, 2- (4- (4-trifluoromethoxyphenylamino) -1-piperidyl) -6-benzothiazolyloxy group 2- (4- (2-pentafluoroethoxyphenylamino) -1-piperidyl) -7-benzothiazolyloxy, 2- (4- (3-pentafluoroethoxyphenylamino) -1-piperidyl) -4-benzothiazolyloxy group, 2- (4- (4-pentafluoroethoxyphenylamino) group) -1-piperidyl) -5-benzothiazolyloxy, 2- (4- (2-fluorophenylamino) -1-piperidyl) -5-benzothiazolyloxy group, 4- (3-fluorophenylamino) -1-piperidyl) -6-benzothiazolyloxy group, 2- (4- (4-fluorophenylamino) -1-piperidyl) -7-benzothiazolyloxy group, 2-phenyl-5- (4-phenoxy-1-piperidyl) -7-benzothiazolyloxy group, 2- (1- (4-trifluoromethoxy-phenyl) - (2- or 3-pyrrolyl) - (4-, 5-) group , ß-, or 7-) benzothiazolyloxy, 2- (1-methyl- (2- or 3-) pyrrolyl) - (4-, 5-, 6- or 7-) benzothiazolyloxy group 2- (4- ( 3- (4-trifluoromethylphenyl) -2-propenyl) - (1-, 2- or 3-) piperadinil) - (4-, 5-, 6- or 7-) benzothiazolyloxy, group 2- (4- (4- trifluoromethoxyphenyl)) - (1-, 2- or 3-) piperadinil) - (4-, 5-, 6- or 7-) benzothiazolyloxy, 2- (4- (4-trifluoromethylphenyl)) - (1-, 2-group - or 3-) piperadinil) - (4-, 5-, 6- or 7-) benzothiazolyloxy, 2- (4-chlorophenylthio) - (4-, 5-, 6- or 7-) -benzothiazolyloxy group or the like. A C1-C6 alkylidene phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a substituted Cl-Cß alkoxy group) or unsubstituted with halogen can be substituted) includes an alkylidene Cl-Cβ phenyl group (on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted Cl-Cβ alkyl group or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), for example, benzylidene group, 1-phenylethylidene group, 2-phenylethylidene group, 3-phenylpropylidene group, 2-phenylpropylidene group, group 4-phenylbutylidene, 5-phenylpentylidene group, 4-phenylpentylidene group, 6-phenylhexylidene group, 2-fluorobenzylidene group, 3-fluorobenzylidene group, 4-fluorobenzylidene group, 2-chlorobenzylidene group, 3-chloro group benzylidene, 4-chlorobenzylidene group, 2-bromobenzylidene group, 3-bromobenzylidene group, 4-bromobenzylidene group, 2-iodobenzylidene group, 3-iodobenzylidene group, 4-iodobenzylidene group, group 2, 3-difluorobenzylidene, 3,4-difluorobenzylidene group , group 3, 5-difluorobenzylidene, group 2, 4-difluorobenzylidene, group 2, 6-difluorobenzylidene, group 2, 3-dichlorobenzylidene, group 3, 4-dichlorobenzylidene, group 3, 5-dichlorobenzylidene, group 2, 4-dichlorobenzylidene, group 2,6-dichlorobenzylidene, 2-fluoro-4-bromobenzylidene group, 4-chloro-3-fluorobenzylidene group, 2,3,4-trichlorobenzylidene group, 3, 4, 5-trifluorobenzylidene group 2, 4,6-trichlorobenzylidene , 4-isopropylbenzylidene group, 4-n-butylbenzylidene group, 4-methylbenzylidene group, group 2-methylbenzylidene, 3-methylbenzylidene group, 2,4-dimethylbenzylidene group, 2,3-dimethylbenzylidene group, 2,6-dimethylbenzylidene group, 3-dimethylbenzylidene group, 2,5-dimethylbenzylidene group, group 2, 4, 6 -trimethylbenzylidene, group 3, 5-ditrifluoromethylbenzylidene, 2,3,4,5,6-pentafluorobenzylidene group, 4-isopropoxybenzylidene group, group 4-n-butoxybenzylidene, 4-methoxybenzylidene group, 2-methoxybenzylidene group, 3-methoxybenzylidene group, 2,4-dimethoxybenzylidene group, group 2, 3-dimethoxybenzylidene, group 2, 6-dimethoxybenzylidene, group 3, 5-dimethoxybenzylidene, group 2, 5-dimethoxybenzylidene, group 2, 4,6-trimethoxybenzylidene, group 3, 5-ditrifluoromethoxybenzylidene, 2-isopropoxybenzylidene group, 3-chloro-4-methoxybenzylidene group, 2-chloro-4-trifluoromethoxybenzylidene group, 3-methyl group 4- fluorobenzylidene, 4-bromo-3-trifluoromethylbenzylidene group, 2-trifluoromethylbenzylidene group, 3-trifluoromethylbenzylidene group, 4-trifluoromethylbenzylidene group, 2-pentafluoroethylbenzylidene group, 3-pentafluoroethylbenzylidene group, 4-pentafluoroethylbenzylidene group, 2-trifluoromethoxybenzylidene group, group 3 -trifluoromethoxybenzylidene, 4-trifluoromethoxybenzylidene group, 2-pentafluoroethoxybenzylidene group, 3-pentafluoroethoxybenzylidene group, 4-pentafluoroethoxybenzylidene group, 2- (2-trifluoromethylphenyl) ethyl group deno, 2- (3-trifluoromethylphenyl) ethylidene group, 2- (4-trifluoromethylphenyl) ethylidene group, 2- (2-trifluoromethoxyphenyl) ethylidene group, 2- (3-trifluoromethoxyphenyl) ethylidene group, 2- (4-trifluoromethoxyphenyl) group ethylidene, 2- (2-pentafluoroethoxyphenyl) ethylidene group, 2- (3-pentafluoroethoxyphenyl) ethylidene group, 2- (4-pentafluoroethoxyphenyl) ethylidene group, 3- (2-trifluoromethylphenyl) propylidene group, 3- (3-trifluoromethylphenyl) group propylidene, 3- (4-trifluoromethylphenyl) propylidene, 3- (2-trifluoromethoxyphenyl) propylidene, 3- (3-trifluoromethoxyphenyl) propylidene, 3- (4-trifluoromethoxyphenyl) propylidene, 3- (3-pentafluoroethoxyphenyl) group propylidene, 3- (4-pentafluoroethoxyphenyl) propylidene group, 4- (3-pentafluoroethoxyphenyl) butylidene group, 5- (4-trifluoromethylphenyl) pentylidene group, 4- (4-trifluoromethylphenyl) pentylidene group, 4- (4-trifluoromethoxyphenyl) group pentylidene, 6- (3-trifluoromethylphenyl) hexylidene group, 6- (4-trifluoromethylphenyl) hexylidene group, group 6- (4-trifluoromethoxyphenyl) hexylidene or the like. A piperidyl group [wherein, in the piperidine ring, at least one selected from the group consisting of an amino group (wherein, in the amino group, at least one selected from the group consisting of a phenyl group [wherein, in the phenyl group, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen can be substituted] and a C 1 -C 6 alkyl group can be substituted); a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted or unsubstituted Cl-Cβ alkoxy group halogen can be substituted); a C 1 -C 3 alkyl phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a C 1 -C 4 alkylenedioxy group, a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted); a Cl-Cβ phenyl alkoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a substituted Cl-Cβ alkoxy group or not substituted with halogen can be substituted); a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted by halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted); an alkyl Cl-Cβ naphthyl group; and an alkylidene Cl-Cß phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes a piperidyl group [wherein, in the piperidine ring, 1 to 3 substituents selected from the group consisting of an amino group (wherein, in the amino group, or 2 groups selected from the group consisting of a phenyl group [wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or not substituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] and a Cl-Cß alkyl group can be substituted); a phenoxy group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-alkoxy group Cß substituted or unsubstituted with halogen can be substituted); a Cl-Cß phenyl alkyl group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a straight or branched C 1 -C 4 alkylenedioxy group containing 1 to 4 carbon atoms, a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted); a Cl-Cβ phenyl alkoxy group as described later (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or not substituted with halogen and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted); a phenyl group as described above (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted); a Cl-Cß-naphthyl alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl part as described later; and a Cl-Cß phenyl alkylidene group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or not substituted by halogen can be substituted) can be substituted], for example, a 1-piperidyl group, 2-piperidyl group, 3-piperidyl group, 4-piperidyl group, group 2, 4- diamino-1-piperidyl, group 2, 4, β-triamino-1-piperidyl, 2-amino-1-piperidyl group, 3-amino-1-piperidyl group, 4-amino-1-piperidyl group, 4-methylamino group -l-piperidyl, 4-ethylamino-1-piperidyl group, 4-n-propylamino-1-piperidyl group, 4-dimethylamino-1-piperidyl group, 4-diethylamino-1-piperidyl group, 4-di-n- group propylamino-1-piperidyl, 4- phenylamino-1-piperidyl group, 4- (N-phenyl-N-methylamino) -1-piperidyl group, 4- (2-fluorophenylamino) -1-piperidyl group, group 4- (3 -fluorophenylamino) -1-piperid ilo, 4- (4-fluorophenylamino) -1-piperidyl group, 4- (2-chlorophenylamino) -1-piperidyl group, 4- (3-chlorophenylamino) -1-piperidyl group 4- (4-chlorophenylamino) -1-piperidyl, 4- (2,3-dichlorophenylamino) -1-piperidyl group, 4- (2,4,6-trifluorophenylamino) -1-piperidyl group, group 4- (2, 4-dichlorophenylamino) -1-piperidyl, 4- (3,4-dichlorophenylamino) -1-piperidyl group, 4- (3,5-dichlorophenylamino) -1-piperidyl group, group 4- (2,3,4,5 , 6-pentafluorophenylamino) -1-piperidyl, 4- (2-trifluoromethylphenylamino) -1-piperidyl group, 4- (2-methylphenylamino) -1-piperidyl group, 4- (2,3-dimethylphenylamino) -1-piperidyl group , 4- (3-trifluoromethylphenylamino) -1-piperidyl group, 4- (2,4,6-trimethylphenylamino) -1-piperidyl group, 4 - (4-trifluoromethylphenylamino) -1-piperidyl group, 4- (2-pentafluoroethylphenylamino group ) -1-piperidyl, 4- (3-pentafluoroethylphenylamino) -1-piperidyl group, 4- (4-pentafluoroethylphenylamino) -1-piperidyl group, 4- (2-trifluoromethoxyphenylamino) -1-piperidyl group, group 4- (2) -methoxyphenylamino) -1-piperidyl, 4- (2,3-dimethoxyphenylamino) -1-piperidyl group, 4- (2,4,6-trimethoxyphenylamino) -1-piperidyl group, group 4- (N -methyl-N- (2,4,6-trimethoxyphenylamino)) -1-piperidyl, 4- (N-methyl-N- (3,4-dimethylphenylamino)) -1-piperidyl group 4- (N-ethyl) -N- (4-chlorophenylamino)) -1-piperidyl, 4- (3-trifluoromethoxyphenylamino) -1-piperidyl group, 4- (4-trifluoromethoxyphenylamino) -1-piperidyl group, 4- (2-pentafluoroethoxyphenylamino) -1 group -piperidyl, 4- (3-pentafluoroethoxyphenylamino) -1-piperidyl group, 4- (4-pentafluoroethoxyphenylamino) -1-piperidyl group, 4- (N-methyl-N- (2-fluorophenyl) amino) -1-piperidyl group , 4- (N-methyl-N- (3-fluorophenyl) amino) -1-piperidyl group, 4- (N-methyl-N- (4-fluorophenyl) amino) -1-piperidyl group, 4-phenoxy group l-piperidyl, group 2, 4-diphenoxy-1-piperidyl, group 2, 4,6-trifenoxi-1-piperidyl, 2- (2-fluorophenoxy) -1-piperidyl group, 3- (3-fluorophenoxy) group - 2-piperidyl, 4- (4-fluorophenoxy) -3-piperidyl group, 2- (2-chlorophenoxy) -4-piperidyl group, 3- (3-chlorophenoxy) -5-piperidyl group, 4- (4-chlorophenoxy) group ) -5-piperidyl, 5- (2-bromophenoxy) -2-p group iperidyl, 6- (3-bromophenoxy) -3-piperidyl group, 4- (4-bromophenoxy) -1-piperidyl group, 3- (2,3-dichlorophenoxy) -2-piperidyl group, 4- (3, 4) group -dichlorophenoxy) -3-piperidyl, 3- (2,4-dichlorophenoxy) -4-piperidyl group, 2- (3, 4, 5-trichlorophenoxy) -3-piperidyl group, group ß- (2, 4, 6 trichlorophenoxy) -2-piperidyl, 3- (2, 3,, 5, 6-pentafluorophenoxy) -1-piperidyl group, 4- (2-methylphenoxy) -1-piperidyl group, 5- (3-methylphenoxy) -2 group - piperidyl, 6- (4-methylphenoxy) -3-piperidyl group, 4- (2-ethylphenoxy) -1-piperidyl group, 2- (3-ethylphenoxy) -1-piperidyl group, 3- (4-ethylphenoxy) group -2-piperidyl, 4- (4-n-propylphenoxy) -3-piperidyl group, 3- (4-tert-butylphenoxy) -4-piperidyl group, 2- (4-n-butylphenoxy) -3-piperidyl group, 1- (2-trifluoromethylphenoxy) -2-piperidyl group, 2- (3-trifluoromethylphenoxy) -1-piperidyl group, 4- (4-trifluoromethylphenoxy) -1-piperidyl group, l- (2-pentafluoroethylphenoxy) -4- group piperidyl, 4- (3-pentafluoroethylphenoxy) -1-piperidyl group, group 4 - (2,3-dimethylphenoxy) -1-piperidyl, 4- (3,4-trimethylphenoxy) -1-piperidyl group, 4- (4-n-pentylphenoxy) -1-piperidyl group, group 4- (4 -n-hexylphenoxy) -1-piperidyl, 4- (2-methoxyphenoxy) -1-piperidyl group, 4- (3-methoxyphenoxy) -1-piperidyl group, 4- (4-methoxyphenoxy) -1-piperidyl group, group 2- (2-ethoxyphenoxy) -3-piperidyl, 3- (3-ethoxyphenoxy) -4-piperidyl group, 4- (4-ethoxyphenoxy) -3-piperidyl group, 3- (4-n-propoxyphenoxy) -2 group -piperidyl, 2- (4-tert-butoxyphenoxy) -1-piperidyl group, 4- (4-n-butoxyphenoxy) -2-piperidyl group, 2- (2-trifluoromethoxyphenoxy) -3-piperidyl group, group 3- ( 3-trifluoromethoxyphenoxy) -4-piperidyl, 4- (4-trifluoromethoxyphenoxy) -3-piperidyl group, 3- (2-pentafluoroethoxyphenoxy) -2-piperidyl group, 2- (4-pentafluoroethoxyphenoxy) -1-piperidyl group, group 4 - (2, 3-dimethoxyphenoxy) -14-piperidyl, 4- (3,4,5-trimethoxyphenoxy) -1-piperidyl group, 4- (4-n-pentyloxyphenoxy) -1-piperidyl group, group 4- (4 -n-hexyloxyphenoxy) -1-piperidyl, 4-benzyl group l-piperidyl, group 2, 4-dibenzyl-1-piperidyl, group 2, 4,6-tribenzyl-1-piperidyl, 2- (2-fluorobenzyl) -1-piperidyl group, 3- (2- (3-fluorophenyl) ethyl group ) -2-piperidyl, 4- (1- (4-fluorophenyl) ethyl) -3-piperidyl group, 2- (3- (2-chlorophenyl) propyl) -4-piperidyl group, group 3- (4- (3 chlorophenyl) butyl) -5-piperidyl, 4- (5- (4-chlorophenyl) pentyl) -2-piperidyl group, 5- (6- (2-bromophenyl) hexyl) -2-piperidyl group, group 6- ( 3-bromobenzyl) -3-piperidyl, 4- (4-bromobenzyl) -1-piperidyl group, 3- (2,3-dichlorobenzyl) -2-piperidyl group, 4- (3, -dichlorobenzyl) -3-piperidyl group , 3- (2,4-dichlorobenzyl) -4-piperidyl group, 2- (3, 4, 5-trichlorobenzyl) -3-piperidyl group, 6- (2, 4, β-trichlorobenzyl) -2-piperidyl group, 3- (2, 3, 4, 5, 6-pentafluorobenzyl) -1-piperidyl group, 4- (2-methylbenzyl) -1-piperidyl group, 5- (2- (3-methylphenyl) ethyl) -2- group piperidyl, ß- (3- (4-methylphenyl) propyl) -3-piperidyl group, 1- (4- (2-ethylphenyl) butyl) -4-piperidyl group, 2- (5- (3-ethyl) group enyl) pentyl) -1-piperidyl, 3- (6- (4-ethylphenyl) hexyl) -2-piperidyl group, 4- (4-n-propylbenzyl) -3-piperidyl group, 3- (4-tert- butylbenzyl) -4-piperidyl, 2- (4-n-butylbenzyl) -3-piperidyl group, l- (2-trifluoromethylbenzyl) -2-piperidyl group, 2- (3-trifluoromethylbenzyl) -1-piperidyl group, group 4 - (4- trifluoromethylbenzyl) -1-piperidyl, l- (2- pentafluoroethylbenzyl) -4-piperidyl group, l- (3-pentafluoroethylbenzyl) -4-piperidyl group, 4- (2,3-dimethylbenzyl) -1- group piperidyl, 1- (3, 4, 5-trimethylbenzyl) -4-piperidyl group, 1- (4-n-pentylbenzyl) -4-piperidyl group, group 4- (4-n-hexylbenzyl) -1-piperidyl, 4- (2-methoxybenzyl) -1-piperidyl group, 1- (2- (3-methoxyphenyl) ethyl) -4-piperidyl group, group 1- (1 - (4-methoxyphenyl) ethyl) -4-piperidyl, 2- (3- (2-ethoxyphenyl) ropy) -3-piperidyl group, 3- (4- (3-ethoxyphenyl) butyl) -4-piperidyl group 4- (5- (4-Ethoxyphenyl) pentyl) -3-piperidyl, 3- (6- (4-n-propoxyphenyl) hexyl) -2-piperidyl group, 2- (4-tert-butoxybenzyl) -1- group piperidyl group, 1- (4-n-butoxybenzyl) -2-piperidyl group, 2- (2-trifluoromethoxybenzyl) -3-piperidyl group, 3- (3-trifluoromethoxybenzyl) -4-piperidyl group, 4- (4-trifluoromethoxybenzyl ) -1-piperidyl group, 3- (2-pentafluoroetoxibencil) -2-piperidyl group, 2- (4-pentafluoroetoxibencil) -1-piperidyl, (2,3-dimethoxybenzyl) -4-piperidyl group l- group, 4- (3,4,5-trimethoxybenzyl) -1-piperidyl, 4- (4-n-pentyloxybenzyl) -1-piperidyl group, 4- (4-n-hexyloxybenzyl) -1-piperidyl group, 4-benzyl-3 group -phenoxy-1-piperidyl, 4-phenoxy-2-methylamino-1-piperidyl group, 4- (4- trif group) luorometoxibencilideno) -1-piperidyl group, 4- (4-chlorobenzylidene) -1-piperidyl group, 4- (4-trifluorometilbencilideno) -1-piperidyl group, 4- (3, 4-dichlorobenzyloxy) - (1-, 2- or 3-) piperidyl, 4- (4-methylbenzyloxy) - (1-, 2- or 3-) piperidyl group, 4- (4-trifluoromethoxybenzyloxy) - (1-, 2- or 3-) piperidyl group, group 4 - (4-methoxyphenyl) - (1-, 2- or 3-) piperidyl, 4- (3,4-dichlorophenyl) - (1-, 2- or 3-) piperidyl group, group 4 - ((1-) 2-) Naphthylmethyl) - (1-, 2- or 3-) -piperidyl, 4- (3,4-methylenedioxyphenyl) - (1-, 2- or 3-) piperidyl group, 4- (4-chlorobenzyloxy) group - (1-, 2- or 3-) piperidyl or the like. A quinolyloxy group (wherein, in the quinoline ring, at least one selected from the group consisting of a halogen atom (c-1), a (c-2) phenoxy group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted], a (c-3) piperadinyl group [ wherein, in the piperadine ring, at least one selected from the group consisting of a C1-C6 alkyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C 1 -C 6 substituted or unsubstituted with halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen can be substituted), a phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of one group phenoxy (where, in the phenyl ring, at least one The group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a halogen atom, an alkyl Cl group, -Cβ substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] and a C2-C6 alkenyl group phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted] and a (C-4) piperidyl group [in where, in the piperidine ring, at least one selected from the group consisting of an amino group (wherein, in the amino group, at least one selected from the group consisting of a phenyl group [wherein, in the phenyl ring, minus one s chosen from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] and a Cl-Cß alkyl group can be substituted ); a phenoxy group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be replaced); a C1-C3 alkyl phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a C1-C4 alkylenedioxy group, a halogen atom, a C1-C3 alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted); a Cl-Cβ phenyl alkoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a substituted Cl-Cβ alkoxy group or not substituted with halogen can be substituted); a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted by halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted); an alkyl Cl-Cβ naphthyl group; and an alkylidene Cl-Cß phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] can be substituted) includes a quinoliloxy group (wherein, in the quinoline ring, 1 to 3 substituents selected from the group consisting of a (c-1) halogen atom , a (c-2) phenoxy group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), (c-3) a piperadinyl group [wherein, in the piperadine ring, 1 to 5, preferably 1 to 3 groups selected from the group consisting of a group alq uilo Cl-Cβ phenyl (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen can be substituted), a phenyl group [wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 groups selected from the group consisting of a phenoxy group (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 groups selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can to be substituted), a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted Cl-Cβ alkoxy group Or unsubstituted with halogen, can be substituted], and a phenylalkenyl group, containing a C2-C6 alkenyl group having at least 1 to 3 double bonds, wherein each double bond contains both a trans form and a cis form ( wherein, in the phenyl ring, at least one group selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can to be substituted) can be substituted] and a (C-4) piperidyl group [wherein, in the piperidine ring, 1 to 3 substituents selected from the group consisting of an amino group (wherein, in the amino group, 1 or 2 groups selected from the group consisting of a phenyl group [wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted Cl-Cβ alkyl group or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] and a Cl-Cß alkyl group can be substituted); a phenoxy group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-alkoxy group Cß substituted or unsubstituted with halogen can be substituted); a C 1 -C 6 alkyl group phenyl (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a straight or branched C 1 -C 4 alkylenedioxy group, a halogen atom, an alkyl Cl group -Cβ substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted); a phenylalkoxy group in which the alkoxy portion is a straight or branched Cl-Cs alkoxy group (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 groups selected from the group consisting of a halogen atom, a group Cl-Cβ alkyl substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted); a phenyl group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen, and a C 1-7 alkoxy group Cß substituted or unsubstituted with halogen, can be substituted); a naphthylalkyl group in which the alkyl portion is a straight or branched Cl-Cß alkyl group; and a Cl-Cß phenyl alkylidene group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] can be substituted), for example, a 2-quinoliloxy group, 3-quinoliloxy group, 4-quinoliloxy group, 5-quinoliloxy group, group 6-quinolyoxy, 7-quinolyoxy group, 8-quinolyoxy group, 4- (1-piperadinyl) -2-quinolyoxy group, 3- (2-piperadinyl) -4-quinolyoxy group, 4- (1-piperadinyl) -3 group -quinolyloxy, 5- (1-piperadinyl) -4-quinolyloxy group, 6- (3,4-dibenzyl-l-piperadinyl) -5-quinolyloxy group, 7- (2, 3, 4-tribenyl-l-piperadinyl group) ) -6-quinolyloxy, 4- (4-benzyl-l-piperadinyl) -2-quinolyoxy group, 3- (4- (2-phenethyl) -1-piperadinyl) -2-quinolyoxy group 4- (4-) (3-phenylpropyl) -1-piperadinyl) -3-quinolyl xi, 5- (4- (4-phenylbutyl) -1-piperadinyl) -4-quinolyoxy group, 6- (4- (5-phenylpentyl) -1-piperadinyl) -5-quinolyoxy group 7- (4-) (6-phenylhexyl) -1-piperadinyl) -6-quinolyoxy, group 8- (4- (2-fluorobenzyl) -1-piperadinyl) -7-quinolyoxy, 2- (4- (3-fluorobenzyl) -1- group piperadinil) -8-quinolyoxy, 3- (4- (4-fluorobenzyl) -1-piperadinyl) -2-quinolyoxy group, 4- (4- (2-chlorobenzyl) -1-piperadinyl) -3-quinolyloxy group, 5- (4- (3-chlorobenzyl) -1-piperadinyl) -4-quinolyoxy group 2- (4- ( 4-chlorobenzyl) -1-piperadinyl) -6-quinolyoxy, 7- (4- (2,3-dichlorobenzyl) -1-piperadinyl) -6-quinolyoxy group, 8- (4- (2,4-dichlorobenzyl) group) -1-piperadinyl) -7-quinolyoxy, 2- (4- (3,4-dichlorobenzyl) -1-piperadinyl) -8-quinolyoxy group, 3- (4- (3,5-dichlorobenzyl) -1-piperadinyl group ) -2-quinolyloxy, 4- (4- (3,4- trichlorobenzyl) -1-piperadinyl) -3-quinolyloxy group, 5- (4- (2, 3, 4, 5, 6-pentafluorobenzyl) group) -1-piperadinyl) -4-quinolyoxy, 6- (4- (2-trifluoromethylbenzyl) -1-piperadinyl) -5-quinolyloxy group, 7- (4- (3-trifluoromethylbenzyl) -1-piperadinyl) -6- group quinolyloxy, 2- (4- (4-trifluoromethylbenzyl) -1-piperadinyl) -6-quinolyloxy group, 2- (4- (4-methylbenzyl) -1-piperadinyl) -8-quinolyloxy group, 3- (4-) group (3, 4-dimethylbenzyl) -1-piperadinyl) -2-quinolyoxy, 4- (4- (2,4,6-trimethylbenzyl) -1-piperadinyl) -3-quinolyoxy group i, group 5- (4- (2-pentafluoroethylbenzyl) -1-piperadinyl) -4-quinolyoxy, 6- (4- (3-pentafluoroethylbenzyl) -1-piperadinyl) -5-quinolyoxy group 7- (4-) (4-pentafluoroethylbenzyl) -1-piperadinyl) -6-quinolyoxy, 2- (4- (4-trifluoromethoxybenzyl) -1-piperadinyl) -6-quinolyoxy group, 2- (4- (3-trifluoromethoxybenzyl) -1- group piperadinil) -8-quinolyoxy, 3- (4- (4-trifluoromethoxybenzyl) -1-piperadinyl) -2-quinolyoxy group, 4- (4- (4-methoxybenzyl) -1-piperadinyl) -3-quinolyoxy group 5- (4- (3, 4-dimethoxybenzyl) -1-piperadinyl) -4-quinolyoxy, 6- (4- (2,4,6-trimethoxybenzyl) -1-piperadinyl) -5-quinolyoxy group 7- (4- (2-pentafluoroethoxybenzyl) -1-piperadinyl) -6-quinolyoxy, group 8- (4- (3-pentafluoroethoxybenzyl) -1-piperadinyl) -2-quinolyoxy, group 3- (4- (4-pentafluoroethoxybenzyl) -1-piperadinyl) -2-quinolyoxy, 4- (4- (2- (4-trifluoromethoxyphenyl) ethyl) -1- piperadinyl) -3-quinolyoxy group, 5- (4- (3- (4-trifluoromethoxyphenyl)) group propyl) -1-piperadinil) -4-quinol Ioxy, 6- (4- (4- (4-trifluoromethoxyphenyl) butyl) -1-piperadinyl) -5-quinolyoxy group, 7- (4- (5- (4-trifluoromethoxyphenyl) pentyl) -1-piperadinyl) - 6-quinolyoxy, group 8- (4- (6- (4-trifluoromethoxyphenyl) hexyl) -1-piperadinyl) -7-quinolyoxy, 2- (4- (2- (4-trifluoromethylphenyl) ethyl) -1-piperadinyl group ) -8-quinolyloxy, 3- (4- (3- (4-trifluoromethylphenyl) propyl) -1-piperadinyl) -2-quinolyoxy group, 4- (4- (4- (4-trifluoromethylphenyl) butyl) -1 group -piperadinyl) -2-quinolyoxy, 5- (4- (5- (4-trifluoromethylphenyl) pentyl) -1-piperadinyl) -2-quinolyoxy group, 6- (4- (6- (4-trifluoromethylphenyl) hexyl) -1-piperadinyl) -2-quinolyoxy, 3- (2-piperidyl) -2-quinolyoxy group, 4- (3-piperidyl) -3-quinolyoxy group, 5- (4-piperidyl) -4-quinolyoxy group 6- (2,4-diamino-l-piperidyl) -5-quinolyoxy, 7- (2,4,6-triamino-l-piperidyl) -6-quinolyloxy group, group 8- (4-amino-1-piperidyl) ) -7-quinolyoxy, 2- (4-amino-1-piperidyl) -8-quinolyoxy group, 3- (4-amino-1-piperidyl) group ) -2-quinolyloxy, 4- (4-methylamino-1-piperidyl) -3-quinolyloxy group, 5- (4-ethylamino-1-piperidyl) -4-quinolyoxy group, 6- (4-n-propylamino) group 1-piperidyl) -5-quinolyloxy, 7- (4-dimethylamino-1-piperidyl) -6-quinolyloxy group, 8- (4-diethylamino-1-piperidyl) -7-quinolyloxy group, 2- (4-diol) group -n-propylamino-l-piperidyl) -8-quinolyloxy, 3- (4-phenylamino-1-piperidyl) -2-quinolyoxy group, 4- (4- (N-phenyl-N-methylamino) -1-piperidyl group ) -3-quinolyloxy, 5- (4- (2-fluorophenyla ino) -1-piperidyl) -4-quinolyoxy group, 6- (4- (3-fluorophenylamino) -1-piperidyl) -5-quinolyoxy group 7- (4- (4-fluorophenylamino) -1-piperidyl) -6-quinolyoxy, group 8- (4- (2-chlorophenylamino) -1-piperidyl) -7-quinolyoxy, group 2- (4- (3- chlorophenylamino) -1-piperidyl) -8-quinolyloxy, 3- (4- (4-chlorophenylamino) -1-piperidyl) -2-quinolyoxy group, 4- (4- (2,3-dichlorophenylamino) -1-piperidyl group ) -3-quinolyloxy, 5- (4- (2,4,6-trifluorophenylamino) -1-piperidyl) -4-quinolyoxy group, 6- (4- (2, 4) group -dichlorophenylamino) -1-piperidyl) -5-quinolinyloxy, 7- (4- (3, -dichlorophenylamino) -1-piperidyl) -6-quinolyloxy group, 8- (4- (3,5-dichlorophenylamino) -1-piperidyl) -7-quinolyloxy group 2- ( 4- (2, 3, 4, 5, 6-pentafluorophenylamino) -1-piperidyl) -8-quinolyloxy, 3- (4- (2-trifluoromethylphenylamino) -1-piperidyl) -2-quinolyoxy group 4- ( 4- (2-Methylphenylamino) -1-piperidyl) -3-quinolyoxy, 5- (4- (2,3-dimethylphenylamino) -1-piperidyl) -4-quinolyoxy group, 6- (4- (2-trifluoromethylphenylamino ) -1-piperidyl) -5-quinolyloxy, 7- (4- (2,4,6-trimethylphenylamino) -1-piperidyl) -β-quinolinyl group, 8- (4- (4-trifluoromethylphenylamino) -1- group piperidyl) -7-quinolyoxy, 2- (4- (2-pentafluoroethylphenylamino) -1-piperidyl) -8-quinolyoxy group, 3- (4- (3-pentafluoroethylphenylamino) -1-piperidyl) -2-quinolyoxy group 4- (4- (4-pentafluoroethylphenylamino) -1-piperidyl) -3-quinolyoxy, 5- (4- (2-trifluoromethoxyphenylamino) -1-piperidyl) -4-quinolyoxy group 6- (4- (2- methoxyphenylamino) -1-piperidyl) -5-quinolyoxy, group or 7- (4- (2,3-dimethoxyphenylamino) -1-piperidyl) -6-quinolyoxy, group 8- (4- (2,4,6-trimethoxyphenylamino) -1-piperidyl) -7-quinolyoxy, group 2 - (4- (N-methyl-N- (2,4,6-trimethoxyphenylamino)) -1-piperidyl) -8-quinolyoxy, 3- (4- (N-methyl-N- (3,4-dimethylphenylamino) group )) -1-piperidyl) -2-quinolyoxy, 4- (4- (3-trifluoromethoxyphenylamino) -1-piperidyl) -2-quinolyoxy group, 5- (4- (4-trifluoromethoxyphenylamino) -1-piperidyl) - 2-quinolyoxy, 6- (4- (2-pentafluoroethoxyphenylamino) -1-piperidyl) -2-quinolyoxy group, 7- (4- (3-pentafluoroethoxyphenylamino) -1-piperidyl) -2-quinolyoxy group 8- ( 4- (4-pentafluoroethoxyphenylamino) -1-piperidyl) -2-quinolyoxy, 2- (4- (2-fluorophenylamino) -1-piperidyl) -3-quinolyoxy group, 3- (4- (3-fluorophenylamino) - group 1-piperidyl) -2-quinolyoxy, 4- (4- (4-fluorophenylamino) -1-piperidyl) -2-quinolyoxy group, 2- (4- (N-ethyl-N- (4-chlorophenylamino)) - 1-piperidyl) -6-quinolyloxy, group 2, 4-di (1-piperadinyl) -6-quinolyloxy, group 3- ( 1-piperidyl) -4- (1-piperadinyl) -2-quinolyoxy, 2,4,6-tri (1-piperidinyl) -3-quinolyoxy group, 5-chloro-8-quinolyoxy group, 2- (4-) group trifluoromethoxyphenoxy) -6-quinolyoxy, 2- (4- (4-trifluoromethoxybenzylidene) -1-piperidyl) -6-quinolyoxy group, 2- (4- (4-chlorobenzylidene) -1-piperidyl) -6-quinolyoxy group 2- (4- (4-trifluoromethylbenzylidene) -1-piperidyl) -6-quinolyoxy, 2- (4-benzyl-l-piperidyl) -4-quinolyoxy group, 2- (3,4-dibenzyl-1-piperidyl) group ) -4-quinolyoxy, 5- (2,3-tribenyl-1-piperidyl) -2-quinolyoxy group, 4- (4- (2-phenethyl) -1-piperidyl) -2-quinolyoxy group 4) - (4- (3-phenylpropyl) -1-piperidyl) -5-quinolyoxy, 4- (4- (4-phenylbutyl) -1-piperidyl) -β-quinolyoxy group, 4- (4- (5-phenylpentyl) group ) -1-piperidyl) -7-quinolyloxy, 2- (4- (6-phenylhexyl) -1-piperidyl) -4-quinolyoxy group, 4- (4- (2-fluorobenzyl) -1-piperidyl) -2 group -quinolyloxy, 2- (4- (3-fluorobenzyl) -1-piperidyl) -4-quinolyoxy group, 2- (4- (4-fluorobenzyl) -1-piperidyl) group -5-quinolyoxy, 2- (4- (2-chlorobenzyl) -1-piperidyl) -6-quinolyoxy group, 2- (4- (3-chlorobenzyl) -1-piperidyl) -7-quinolyoxy group, 5- (4- (4-chlorobenzyl) -1-piperidyl) -4-quinolyoxy, 6- (4- (2,3-dichlorobenzyl) -1-piperidyl) -4-quinolyoxy group, 7- (4- (2, 4-dichlorobenzyl) -1-piperidyl) -8-quinolyoxy, 2- (4- (3,4-dichlorobenzyl) -1-piperidyl) -8-quinolyoxy group, 4- (4- (3,5-dichlorobenzyl) group) -1-piperidyl) -2-quinolyoxy, 4- (4- (3,4,5-trichlorobenzyl) -1-piperidyl) -5-quinolyoxy group, 4- (4- (2,3,4,5, 6-pentafluorobenzyl) -1-piperidyl) -2-quinolyoxy, 4- (4- (2-trifluoromethylbenzyl) -1-piperidyl) -6-quinolyoxy group, 4- (4- (3-trifluoromethylbenzyl) -1-piperidyl group ) -7-quinolyoxy, 2- (4- (4-trifluoromethylbenzyl) -1-piperidyl) -8-quinolyoxy group, 5- (4- (4-methylbenzyl) -1-piperidyl) -4-quinolyoxy group 6 - (4- (3, 4-dimethylbenzyl) -1-piperidyl) -4-quinolyoxy, group 8- (4- (2,4,6-trimethylbenzyl) -1-piperidyl) -4-quinolyoxy, group 3- ( 4- (2-pentafluo roethylbenzyl) -1-piperidyl) -2-quinolyoxy, group 8- (4- (3-pentafluoroethylbenzyl) -1-piperidyl) -5-quinolyloxy, 4- (4- (4-pentafluoroethylbenzyl) -1-piperidyl) -β-quinolyloxy group 4- (4- ( 2-trifluoromethoxybenzyl) -1-piperidyl) -7-quinolyloxy, 5- (4- (3-trifluoromethoxybenzyl) -1-piperidyl) -4-quinolyoxy group, 6- (4- (4-trifluoromethoxybenzyl) -1-piperidyl group ) -5-quinolyoxy, 7- (4- (4-methoxybenzyl) -1-piperidyl) -5-quinolyoxy group, 6- (4- (3,4-dimethoxybenzyl) -1-piperidyl) -4-quinolyoxy group, 7- (4- (2, 4, ß-trimethoxybenzyl) -1-piperidyl) -4-quinolyloxy group, 5- (4- (2-pentafluoroethoxybenzyl) -1-piperidyl) -4-quinolyoxy group 4- ( 4- (3-pentafluoroethoxybenzyl) -1-piperidyl) -2-quinolyoxy, 6- (4- (4-pentafluoroethoxybenzyl) -1-piperidyl) -4-quinolyoxy group, 4- (4- (2- (4- trifluoromethoxyphenyl) ethyl) -1-piperidyl) -2-quinolyloxy, 4- (4- (3- (4-trifluoromethoxyphenyl) propyl) -1-piperidyl) -2-quinolyloxy group, 4- (4- (4- ( 4-trifluoromethoxyphenyl) butyl) -1-piperidyl) -2-quinolyoxy, group 4- ( 4- (5- (4-trifluoromethoxyphenyl) pentyl) -1-piperidyl) -3-quinolyoxy, 4- (4- (6- (4-trifluoromethoxyphenyl) hexyl) -1-piperidyl) -3-quinolyoxy group 4 - (4- (2- (4-trifluoromethylphenyl) ethyl) -1-piperidyl) -2-quinolyloxy, group 5- (4- (3- (4-trifluoromethylphenyl) propyl) -1-piperidyl) -2-quinolyoxy, 6- (4- (4- (4-trifluoromethylphenyl) butyl) -1- piperidyl) -2-quinolyoxy group, 7- (4- (5- (4-trifluoromethylphenyl) pentyl) -2-piperidyl) -2- group quinolyloxy, 5- (4- (6- (4-trifluoromethylphenyl) hexyl) -1-piperidyl) -2-quinolyoxy group, 2- (4-phenoxy-1-piperidyl) -4-quinolyoxy group 2- (3-quinoline) , 4-diphenoxy-1-piperidyl) -4-quinolyloxy, 5- (2, 3, 4-trifenoxy-1-piperidyl) -2-quinolyoxy group, 4- (4- (2-fluorophenoxy) -1-piperidyl group ) -2-quinolyoxy, group 2 - (4 - (3-fluorophenoxy) -1-piperidyl) -4-quinolyoxy, group 2 -. (4 - (4-fluorophenoxy) -1-piperidyl) -5- quinolyloxy, group 2 -. (4 - (2-chlorophenoxy) -1-piperidyl) -6-quinolyloxy, group 2 - (4 - (3-chlorophenoxy) -1-piperidyl) -7-quinolyoxy, group po 5 - (4 - (4-chlorophenoxy) -1-piperidyl) -4-quinolyoxy, 6- (4- (2,3-dichlorophenoxy) -1-piperidyl) -4-quinolyoxy group 7- ( 4- (2,4-dichlorophenoxy) -1-piperidyl) -4-quinolyoxy, 2- (4- (3,4-dichlorophenoxy) -1-piperidyl) -8-quinolyoxy group, 4- (4- (3 , 5-dichlorophenoxy) -1-piperidyl) -2-quinolyloxy, group 4- (4- (3,4,5-trichlorophenoxy) -1-piperidyl) -5-quinolyloxy, group 4- (4- (2, 3 , 4,5, 6-pentafluorophenoxy) -1-piperidyl) -2-quinolyloxy, 4- (4- (2-trifluoromethylphenoxy) -1-piperidyl) -β-quinolyloxy group, 4- (4- (3-trifluoromethylphenoxy) group ) -1-piperidyl) -7-quinolyloxy, 2- (4- (4-trifluoromethylphenoxy) -1-piperidyl) -4-quinolyloxy group, 5- (4- (4-methylphenoxy) -1-piperidyl) -4 group -quinolyloxy, 6- (4- (3,4-dimethylphenoxy) -1-piperidyl) -4-quinolyloxy group, 7- (4- (2, 4,6-trimethylphenoxy) -1-piperidyl) -4-quinolyoxy group , 4- (4- (2-pentafluoroethylphenoxy) -1-piperidyl) -2-quinolyloxy group, 4- (4- (3-pentafluoroethylphenoxy) -1-piperidyl) -5-quinolyloxy group 4- (4- ( 4-pe ntafluoroethylphenoxy) -1-piperidyl) -6-quinolyoxy, 4- (4- (2-trifluoromethoxyphenoxy) -1-piperidyl) -7-quinolyoxy group, 5- (4- (3-trifluoromethoxyphenoxy) -1-piperidyl) - 4-quinolyloxy, 6- (4- (4-trifluoromethoxyphenoxy) -1-piperidyl) -5-quinolyloxy group, 7- (4- (4-methoxyphenoxy) -1-piperidyl) -5-quinolyoxy group 6- ( 4- (3, 4-dimethoxyphenoxy) -1-piperidyl) -4-quinolyoxy, group 8- (4- (2,4,6-trimethoxyphenoxy) -1-piperidyl) -4-quinolyoxy, group 5- (4- (2-pentafluoroethoxyphenoxy) -1-piperidyl) -4-quinolyoxy, 4- (4- (3-pentafluoroethoxyphenoxy) -1-piperidyl) -2-quinolyloxy group, 6- (4- (4-pentafluoroethoxyphenoxy) -1- group piperidyl) -4-quinolyoxy group 2, 5, 6-triphenoxy-7-quinolyoxy, group 4, 5,6-trichloro-2-quinolyoxy, 2-phenoxy-6-bromo-5-quinolyoxy group, 2- (2,3-dimethylphenoxy) -5 group -quinolyloxy, 2- (3,4,5-trimethylphenoxy) -6-quinolyloxy group, 2- (2,3-dimethoxyphenoxy) -7-quinolyloxy group, 2- (3,4,5-trimethoxyphenoxy) -8- group quinolyloxy, 2- (2, 3, 4, 5, 6-pentafluorophenoxy) -β-quinolyloxy group, 2- (2-methylphenoxy) -4-quinolyloxy group, 2- (3-methylphenoxy) -3-quinolyloxy group, group 3- (4-methylphenoxy) -2-quinolyoxy, 4- (2-methoxyphenoxy) -3-quinolyoxy group, 5- (3-methoxyphenoxy) -4-quinolyoxy group, 6- (4-methoxyphenoxy) -5-quinolyoxy group , 7- (2-fluorophenoxy) -6-quinolyoxy group, 8- (3-fluorophenoxy) -7-quinolyoxy group, 2- (4-fluorophenoxy) -5-quinolyoxy group, 3- (2-chlorophenoxy) -2 group -quinolyloxy, 4- (3-chlorophenoxy) -6-quinolyloxy group, 5- (4-chlorophenoxy) -2-quinolyloxy group, 6- (2-bromophenoxy) -3-quinolyloxy group, 7- (3-bromophenoxy) group -4-quinolyoxy, group 8- (4-bromophenoxy) -2-quinolyoxy, group 2- (2, 3-dic) lorophenoxy) -6-quinolyloxy, 3- (3,4-dichlorophenoxy) -7-quinolyloxy group, 4- (2,4-dichlorophenoxy) -5-quinolyloxy group, 2- (3, 4, 5-trichlorophenoxy) - 6-quinolyoxy, 2- (2,4-bichlorophenoxy) -5-quinolyoxy group, 2- (3-trifluoromethylphenoxy) -7-quinolyoxy group, 2- (4- (3- (4-trifluoromethylphenyl) -2 group -propenyl) - (1-, 2- or 3-) piperadinil) - (3-, 4-, 5-, 6-, 7- or 8-) quinolyoxy, group 2- (4- (4-methoxyphenyl) - (1-, 2- or 3-) -piperadinil) - (3-, 4-, 5-, 6-, 7- or 8-) quinolyoxy, 2- (4- (3,4-dimethylphenyl) - - group ( 1-, 2- or 3 -) - piperadinil) - (3-, 4-, 5-, 6-, 7- or 8-) quinolyloxy, group 2- (4- (4-fluorophenyl) - (1-) 2- or 3-) -piperadinil) - (3-, 4-, 5-, 6-, 7- or 8-) quinolyloxy, 2- (4- (4-trifluoromethylphenyl) - (1-, 2- or 3-) -piperadinil) - (3-, 4-, 5-, 6-, 7- or 8-) quinolyloxy, 2- (4- (4-methylphenyl) - (1-, 2- or 3-) -piperadinil) - (3-, 4-, 5-, 6-, 7- or 8-) quinolyloxy, group 2- (4- (3,4-dichlorophenyl) - (1-, 2- or 3) -) -piperadinil) - (3-, 4-, 5-, 6-, 7- or 8-) quinolyoxy, 2- (4- (4-trifluoromethoxyphenyl) - (1-, 2- or 3-) - group piperadinil) - (3-, 4-, 5-, 6-, 7- or 8-) quinolyoxy, 2- (4- (4- (4-chlorophenoxy) phenyl) - (1-, 2- or 3-) ) -piperadinil) - (3-, 4-, 5-, ß-, 7- or 8-) quinolyloxy, 2- (4- (3,4-dichlorobenzyloxy) - (1-, 2- or 3-) group -piperadinil) - (3-, 4-, 5-, 6-, 7- or 8-) quinolyoxy, 2- (4- (4-methylbenzyloxy) - (1-, 2- or 3-) -piperadinyl group) - (3-, 4-, 5-, ß-, 7- or 8-) quinolyloxy, 2- (4- (4-trifluoromethoxybenzyloxy) - (1-, 2- or 3-) piperadinyl group) - (3-) , 4-, 5-, 6-, 7- or 8-) quinolyloxy, 2- (4- (4-ethoxyphenyl) - (1-, 2- or 3-) -piperadinyl group) - (3-, 4- , 5-, 6-, 7- or 8-) quinolyloxy, 2- (4- (3,4-dichlorophenyl) - (1-, 2- or 3 -) - piperadinyl) - (3- , 4-, 5-, 6-, 7- or 8-) quinolyloxy, 2- (4 - ((l- or 2-) naphthylmethyl) - (l-, 2- or 3-) -piperadinyl group) - ( 3-, 4-, 5-, ß-, 7- or 8-) quinolyloxy, 2- (4- (3,4-methylenedioxyphenyl) - (1-, 2- or 3-) -piperadinyl group) - (3 -, 4-, 5-, ß-, 7- or 8-) quinolyloxy, 2- (4- (4-chlorobenzyloxy) - (1-, 2- or 3-) -piperadinyl group) - (3-, 4 -, 5-, 6-, 7- or 8-) quinolyoxy or the like. A Cl-Cß alkyl group substituted with Cl-Cß phenyl alkoxy (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted by halogen can be substituted) is a group composed of a C 1 -C 6 alkoxy phenyl group and C 1 -C 6 alkyl group which can be substituted by 1 to 5, preferably 1 to 3 substituents selected from the group which consists of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted or unsubstituted Cl-Cβ alkoxy group with halogen as defined above, examples of which include a benzyloxymethyl group, group 2 phenylethoxymethyl, 3-phenylpropoxymethyl group, 2-phenylpropoxymethyl, 4-phenylbutoxymethyl group, 5-phenylpentoxymethyl group, 4-phenylpentoxymethyl group, 6-phenylhexyloxymethyl groupFluorobenciloximetilo-2, group, 4- fluorobenciloximetilo group, 4-clorobenciloximetilo, 3- clorobenciloximetilo group, 2-clorobenciloximetilo group, group 3, 5-diclorobenciloximetilo, group 3, 4-diclorobenciloximetilo, group 2- (3-fluorobenzyloxy) ethyl, group 1- (4-fluorobenzyloxy) ethyl, 3- (2- (2-fluorophenyl) ethoxy) propyl group, 4- (2- (3-fluorophenyl) ethoxy) butyl group, 5- (2- (4-fluorophenyl) group ) ethoxy) pentyl, 6- (2-chlorobenzyloxy) hexyl group, 3-chlorobenzyloxymethyl group, 2- (4-chlorobenzyloxy) ethyl group, 1- (2-fluoro-4-bromobenzyloxy) ethyl group, 3- (4-) group chloro-3-fluorobenzyloxy) propyl, 4- (2,3,4-trichlorobenzyloxy) butyl group, 5- (3,4,5-trifluorobenzyloxy) pentyl group, 6- (2, 3, 4, 5, 6- pentafluorobenzyloxy) hexyl, 2,4,6-trichlorobenzyloxymethyl group, 2- (4-isopropylbenzyloxy) ethyl group, 1- (4-n-butylbenzyloxy) ethyl group, 3- (4-methylbenzyloxy) propyl group, group 4- (2 -methylbenzyloxy) butyl, 5- (3-methylbenzyloxy) pentyl group, group 6- (2, 4- dimethylbenzyloxy) hexyl, group 2, 3-dimethylbenzyloxymethyl, 4-methylbenzyloxymethyl group, 4-ethylbenzyloxymethyl group, 3, 5-dimethylbenzyloxymethyl group, 4-isopropylbenzyloxymethyl group, 3-trifluoromethylbenzyloxymethyl group, 4-trifluoromethylbenzyloxymethyl group, 2-trifluoromethylbenzyloxymethyl group, 2- (2,6-dimethylbenzyloxy) ethyl group, 1- (3,5-dimethylbenzyloxy) ethyl group, 3- (2,5-dimethylbenzyloxy) propyl group, 4- (2,4,6-trimethylbenzyloxy) butyl group group 5- (3, 5-ditrifluorometilbenciloxi) pentyl group, 6- (4-isopropoxibenciloxi) hexyl group, 4-n-butoxibenciloximetilo group, 4-trifluorometoxibenciloximetilo group, 2-trifluorometoxibenciloximetilo group, 3-trifluorometoxibenciloximetilo group, 3-methoxybenzyloxymethyl group 2- (4-methoxybenzyloxy) ethyl, l- (2-methoxybenzyloxy) ethyl group, 3- (3-methoxybenzyloxy) propyl group, 4- (2,4-dimethoxybenzyloxy) butyl group, 5- (2,3-dimethoxybenzyloxy) group ) pentyl, 6- (2,6-dimethoxybenzyloxy) hexyl group, group 3, 5-dimetoxibenciloximetilo, group 2- (2, 5-dimethoxybenzyloxy) ethyl group, 1- (2, 4, 6-trimetoxibenciloxi) ethyl group, 3- (3,5-ditrifluorometoxibenciloxi) propyl group, 4- (2-isopropoxibenciloxi) butyl, 5- (3-chloro-4-methoxybenzyloxy) pentyl group, 6- (2-chloro-4-trifluoromethoxybenzyloxy) exo group, 3-methyl-4-fluorobenzyloxymethyl group, group 2 - (4-bromo-3 -trifluoromethylbenzyloxy) ethyl, l- (2- (2-chlorophenyl) ethoxy) methyl group, 3- (2- (3-chlorophenyl) ethoxy) propyl group, 4- (2- (4-chlorophenyl) ethoxy) butyl group, group 5- (2-trifluoromethylbenzyloxy) pentyl group, ß- (3-trifluoromethylbenzyloxy) hexyl group, 4-trifluorometilbenciloximetilo, group 2- (2-trifluoromethoxybenzyloxy) ethyl group, l- (3-trifluoromethoxybenzyloxy) ethyl group, 3- (4 -trifluoromethoxybenzyloxy) propyl, 4- (2- (2-trifluoromethylphenyl) ethoxy) butyl group, 5- (2- (3-trifluoromethylphenyl) ethoxy) pentyl group, 6- (2- (4-trifluoromethylphenyl) ethoxy) hexyl group, Group (2- (2-trifluoromethoxyphenyl) ethoxy) methyl, group 2- (2- (3-trifluoromethoxyphenyl) ethoxy) ethyl, group 1- (2- (4-trifluoromethoxyphenyl) ethoxy) ethyl, 3- (3- (2-trifluoromethylphenyl) propoxy) propyl group, group 4- (3- (3 trifluoromethylphenyl) propoxy) butyl group, 5- (3- (4-trifluoromethylphenyl) propoxy) pentyl group, 6- (3- (2-trifluoromethylphenyl) propoxy) pentyl group, (3- (3-trifluorornetoxifenil) propoxy) methyl, 2- (3- (4-trifluoromethoxyphenyl) propoxy) ethyl group, l- (4- (3-trifluoromethylphenyl) butoxy) ethyl group, 3- (5- (4-trifluoromethylphenyl) pentoxy) butyl group 4- (4 - (4-trifluoromethylphenyl) pentoxy) butyl group, 5- (4- (4-trifluoromethoxyphenyl) pentoxy) pentyl group, 6- (6- (3-trifluoromethylphenyl) hexyloxy) hexyl group, (6- (4-trifluoromethylphenyl) hexyloxy ) methyl, 2- (6- (4-trifluoromethoxyphenyl) hexyloxy) ethyl group or the like. A piperidyl group [wherein, in the piperidine ring, at least one selected from the group consisting of a phenoxy group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cß alkyl group substituted with Cl-Cß phenyl alkoxy (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), an alkyl group Cl-Cβ phenoxy (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted or unsubstituted Cl-Cβ alkoxy group with halogen can be substituted) and a Cl-Cß phenyl alkyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and n Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes a piperidyl group [wherein, in the piperidine ring, 1 to 3 substituents selected from the group consisting of a phenoxy group (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) a Cl-Cß alkyl group substituted with Cl-Cβ phenyl alkoxy (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, an alkyl Cl group -Cβ substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cβ phenoxy alkyl group having a straight alkyl group or branched chain containing 1 to 6 carbon atoms in the alkyl part described later (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, an alkyl group Cl-Cβ substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) and a Cl-Cβ phenyl alkyl group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted, for example, a 1-piperidyl group, 4-piperidyl group, 2-piperidyl group, 3-piperidyl group, 4-phenoxy-1-piperidyl group, 2, 4-diphenoxy-1-piperidyl group, 2, 4, 6-triphenoxy group 1-piperidyl, 2- (2-fluorophenoxy) group -1-piperidyl, 3- (3-fluorophenoxy) -2-piperidyl group, 4- (4-fluorophenoxy) -3-piperidyl group, 2- (2-chlorophenoxy) -4-piperidyl group, 3- (3-) group chlorophenoxy) -5-piperidyl, 4- (4-chlorophenoxy) -2-piperidyl group, 5- (2-bromophenoxy) -2-piperidyl group, 6- (3-bromophenoxy) -3-piperidyl group, group 4- ( 4-bromophenoxy) -1-piperidyl, 3- (2, 3-dichlorophenoxy) -2-piperidyl group, 4- (3,4-dichlorophenoxy) -3-piperidyl group, 3- (2,4-dichlorophenoxy) - group 4-piperidyl, 2- (3,4,5-trichlorophenoxy) -3-piperidyl group, 6- (2,4,6-trichlorophenoxy) -2-piperidyl group, 3- (2, 3, 4, 5, 6-pentafluorophenoxy) -1-piperidyl, 4- (2-methylphenoxy) -1-piperidyl group, 5- (3-methylphenoxy) -2-piperidyl group, 6- (4-methylphenoxy) -3-piperidyl group, group 3 - (2-ethylphenoxy) -4-piperidyl, 2- (3-ethylphenoxy) -1-piperidyl group, 3- (4-ethylphenoxy) -2-piperidyl group, 4- (4-n-propylphenoxy) -3- group piperidyl, 3- (4-tert-butylphenoxy) -4-piperidyl group, 2- (4-n-butylphenoxy) -3-piperidyl group, group 4 - (2-trifluoromethylphenoxy) -2-piperidyl, 2- (3-trifluoromethylphenoxy) -1-piperidyl group, 3- (4-trifluoromethylphenoxy) -1-piperidyl group, 1- (2-pentafluoroethylphenoxy) -4-piperidyl group, l- (3-pentafluoroethylphenoxy) -4-piperidyl group, 4- (2,3-dimethylphenoxy) group -1-piperidyl, 3- (3,4-trimethylphenoxy) -4-piperidyl group, 1- (4-n-pentylphenoxy) -4-piperidyl group, 4- (4-n-hexylphenoxy) -1- group piperidyl, 4- (2-methoxyphenoxy) -1-piperidyl group, 1- (3-methoxyphenoxy) -4-piperidyl group, 3- (4-methoxyphenoxy) -4-piperidyl group, 2- (2-ethoxyphenoxy) group - 3-piperidyl, 3- (3-ethoxyphenoxy) -4-piperidyl group, 4- (4-ethoxyphenoxy) -3-piperidyl group, 3- (4-n-propoxyphenoxy) -2-piperidyl group, 2- (4-group -tert-butoxyphenoxy) -2-piperidyl, 4- (4-n-butoxyphenoxy) -2-piperidyl group, 2- (2-trifluoromethoxyphenoxy) -3-piperidyl group, 3- (3-trifluoromethoxyphenoxy) -4-piperidyl group , 4- (4-trifluoromethoxyphenoxy) -3-piperidyl group, 3- (2-pentafluoroethoxyphenoxy) -2-piperidyl group, 2- (4-pentafluoroethoxyphenoxy) -1-piperidyl group, 3- (2,3-dimethoxyphenoxy) group -4-piperidyl, Group 4 - (3,4,5-trimethoxyphenoxy) -1-piperidyl, 4- (4-n-pentyloxyphenoxy) -1-piperidyl group, 4- (4-n-hexyloxyphenoxy) -1-piperidyl group, group 4 -benzyl-1-piperidyl, group 2, 4-dibenzyl-1-piperidyl, group 2, 4,6-tribenzyl-1-piperidyl, 2- (2-fluorobenzyl) -1-piperidyl group, 3- (2-group (3-fluorophenyl) ethyl] -2-piperidyl, 4- (1- (4-fluorophenyl) ethyl] -3-piperidyl group, 2- (3- (2-chlorophenyl) propyl] -4-piperidyl group, group 3 - (4- (3-chlorophenyl) butyl] -5-piperidyl, 4- (5- (4-chlorophenyl) pentyl] -2-piperidyl group, 5 - ((β- (2-bromophenyl) hexyl] -2 group -piperidyl, ß- (3-bromobenzyl) -3-piperidyl group, 4- (4-bromobenzyl) -1-piperidyl group, 3- (2,3-dichlorobenzyl) -2-piperidyl group, group 4- (3, 4-dichlorobenzyl) -3-piperidyl, 3- (2,4-dichlorobenzyl) -4-piperidyl group, 2- (3, 4, 5-trichlorobenzyl) -3-piperidyl group, group 6- (2, 4, 6 -trichlorobenzyl) -2-piperidyl, 3- (2, 3, 4, 5, β-pentafluorobenzyl) -1-piperidyl group, 4- (2-methylbenzyl) -1-piperidyl group, 5- (2- (3-methylphenyl) ethyl] -2-piperidyl group, 6- (3- (4-methylphenyl) propyl] -3-piperidyl group, 1- (4- (2-ethylphenyl) butyl] - group 4-piperidyl, 2- (5- (3-ethylphenyl) pentyl] -1-piperidyl group, 3- (6- (4-ethylphenyl) hexyl] -2-piperidyl group, 4- (4-n-propylbenzyl) group -3-piperidyl, 3- (4-tert-butylbenzyl) -4-piperidyl group, 2- (4-n-butylbenzyl) -3-piperidyl group, l- (2-trifluoromethylbenzyl) -2-piperidyl group 2 - (3-trifluoromethylbenzyl) -1-piperidyl, 4- (4-trifluoromethylbenzyl) -1-piperidyl group, l- (2-pentafluoroethylbenzyl) -4-piperidyl group, l- (3-pentafluoroethylbenzyl) -4-piperidyl group , 4- (2,3-dimethylbenzyl) -1-piperidyl group, 1- (3, 4, 5-trimethylbenzyl) -4-piperidyl group, 1- (4-n-pentylbenzyl) -4-piperidyl group, group 4 - (4-n-hexylbenzyl) -1-piperidyl, 4- (2-methobenzyl) -1-piperidyl group, 1- (2- (3-methoxyphenyl) ethyl] -4-piperidyl group, group 1- (1- (4-methoxyphenyl) ethyl] -4-piperidyl, 2- (3- (2-ethoxyphenyl) propyl] -3-piperidyl group, group 3- (4- ( 3-ethoxyphenyl) butyl] -4-piperidyl, 3- (4- (3-ethoxyphenyl) butyl] -4-piperidyl group, 4- (5- (4-ethoxyphenyl) pentyl] -3-piperidyl group, group 3 - (6- (4-n-propoxyphenyl) hexyl] -2-piperidyl, group 2-- (4-tert-butoxybenzyl) -1-piperidyl, group 1- (4-n-butoxybenzyl) -2-piperidyl, group 2- (2-trifluoromethoxybenzyl) -3-piperidyl, 3- (3-trifluoromethoxybenzyl) -4-piperidyl group, 4- (4-trifluoromethoxybenzyl) -1-piperidyl group, 3- (2-pentafluoroethoxybenzyl) -2-piperidyl group , 2- (4-pentafluoroethoxybenzyl) -1-piperidyl group, l- (2,3-dimethoxybenzyl) -4-piperidyl group, 4- (3,4,5-trimethoxybenzyl) -1-piperidyl group, group 4- ( 4-n-pentyloxybenzyl) -1-piperidyl, 4- (4-n-hexyloxybenzyl) -1-piperidyl group, 4-benzyl-3-phenoxy-1-piperidyl group, 4-benzyloxymethyl-1-piperidyl group, group 2 , 4-dibenzyloxymethyl-1-piperidyl, group 2, 4, ß-tribenzyloxymethyl-1-piperidyl, group 2 - ((2-fluorobenzyloxy) methyl] -1-piperidyl, group 3- (2- (2- (3- fluorophenyl) ethoxy] ethyl) -2-piperidyl, group 4- (1- (1- (4) -fluorophenyl) ethyl] ethoxy) -3-piperidyl, 2- (3- (3- (2-chlorophenyl) propoxy] propyl) -4-piperidyl group, 3- (4- (4- (3-chlorophenyl) butoxy] butyl) -5-piperidyl group, group 4- (5- (5- (4-chlorophenyl) pentyloxy] pentyl) -2-piperidyl, 5- (6- (6- (2-bromophenyl) hexyloxy] -2-piperidyl group, 6- (3-methoxybenzymethyl) - 3-piperidyl, 4- (4-bromobenzyloxymethyl) -1-piperidyl group, 3- (2,3-dichlorobenzyloxymethyl) -2-piperidyl group, 4- (3,4-dichlorobenzyloxymethyl) -3-piperidyl group, group 3- (2, 4-dichlorobenzyloxymethyl) -4-piperidyl, 2- (3,4,5-trichlorobenzyloxymethyl) -3-piperidyl group, 6 - (2,4,6-trichlorobenzyloxymethyl) -2-piperidyl group, 3- (2, 3) group , 4, 5, 6-pentafluorobenzyloxymethyl) -1-piperidyl, 4- (2-methylbenzyloxymethyl) -1-piperidyl group, 5- (2- (2- (3-methylphenyl) ethoxy] ethyl) -2-piperidyl group, 6- (3- (3- (4-methylphenyl) propoxy] propyl) -3-piperidyl group, group 1- (4- (4- (2-ethylphenyl) butoxy] butyl) -4-piperidyl, group 2- ( 5- (5- (3-Ethylphenyl) pentyloxy] pentyl) -1-piperidyl, 3- (6- (6- (4-ethylphenyl) hexyloxy] group] hexyl) -2-piperidyl, 4- (4-n-propylbenzyloxymethyl) -3-piperidyl group, 3- (4-tert-butylbenzyloxymethyl) -4-piperidyl group, 2- (4-n-butylbenzyloxymethyl) -3- group piperidyl, D 1 - (2-trifluoromethylbenzyloxymethyl) -2-piperidyl group, 2- (trifluoromethylbenzyloxymethyl) -1-piperidyl group, 4 - (4-trifluoromethylbenzyloxymethyl) -1-piperidyl group, group 1- • ( 2-pentafluoroethylbenzyloxymethyl) -4-piperidyl, 1- (3-pentafluoroethylbenzyloxymethyl) -4-piperidyl group, 4- (2,3-dimethylbenzyloxymethyl) -1-piperidyl group, l- (3,4,5-trimethylbenzyloxymethyl) group) -4-piperidyl, l- (4-n-pentylbenzyloxymethyl) -4-piperidyl group, 4- (4-n-hexylbenzyloxymethyl) -1-piperidyl group, 4- (2-methoxybenzyloxymethyl) -1-piperidyl group, group 1 - (2- (2- (3-methoxyphenyl) ethoxy] ethyl) -4-piperidyl, group 1- (1- (1- (4-methoxy-enyl) -ethoxy] -ethyl) -4-piperidyl, group 2- (3 - (3- (2-ethoxyphenyl) propoxy] propyl) -3-piperidyl, 3- (4- (4- (3-ethoxyphenyl) butoxy] butyl) -4-piperidyl group, group 4- (5- (5 - (4- ethoxyphenyl) pentyloxy] pentyl) -3-piperidyl, 3- (6- (6- (4-n-propoxy-enyl) -hexyloxy] hexyl) -2-piperidyl group, 2- (4-tert-butoxy-benzyloxymethyl) -l- group piperidyl, 1- (4-n-butoxybenzyloxymethyl) -2-piperidyl group, 2- (2-trifluoromethoxybenzyloxymethyl) -3-piperidyl group, 3- (3-trifluoromethoxybenzyloxymethyl) -4-piperidyl group, 4- (4- group trifluoromethoxybenzyloxymethyl) -l-piperidyl, 3- (2-pentafluoroethoxybenzyloxymethyl) -2-piperidyl group, 2- (4-pentafluoroethoxybenzyloxymethyl) -1-piperidyl group, l- (2,3-dimethoxybenzyloxymethyl) -4-piperidyl group, 4- (3,4,5-trimethoxybenzyloxymethyl) -1-piperidyl group, 4- (4-n-pentyloxybenzyloxymethyl) -1-piperidyl group, 4- (4-n-hexyloxybenzyloxymethyl) -1-piperidyl group, group 4- benzyloxymethyl-3-phenoxy-1-piperidyl, 4-benzyl-3-phenoxy-1-piperidyl group, 4- (4-chlorofenoxymethyl) - (1, 2 or 3) piperidyl group or the like. A pyridyloxy group (wherein, in the pyridine ring, at least one selected from the group consisting of a (d-1) piperidyl group [wherein, in the piperidine ring, at least one selected from the group consisting of a phenoxy group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cß alkyl group substituted with Cl-Cβ phenyl alkoxy (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cβ phenoxy alkyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß sub alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) and a Cl-Cβ phenyl alkyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can to be substituted] and a piperadynyl group (d-2) [wherein, in the piperadine ring, at least one selected from the group consisting of a Cl-Cβ alkoxycarbonyl group, a Cl-Cß furyl alkyl group [wherein, in the furan ring, at least one phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group) substituted or unsubstituted with halogen can be substituted), a C 1 -C 6 alkyl pyridyl group [wherein, in the pyridine ring, at least one selected from the group consisting of a furyl group and a phenyl group (wherein , in the phenyl ring, to me one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted], an alkyl group Cl-Cβ benzothienyl (wherein, in the benzothiophene ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted or unsubstituted Cl-Cβ alkoxy group with halogen can be substituted), a C2-C6 alkenyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C3 alkyl group substituted or unsubstituted with halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen can be substituted), a C 1 -C 6 alkyl benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted], a C2-C6 alkenyl benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted], a C1-C6 alkyl thiazolyl group [ wherein, in the thiazole ring, at least one phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted by halogen can be substituted) can be substituted], a C1-C6 alkyl phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted by halogen and a Cl-Cβ alkoxy group substituted or unsubstituted by halogen can be substituted), an alkyl Cl-Cß indolyl group (wherein, in the indole ring, at least one selected from the a group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) and a Cl-Cβ phenyl alkyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a benzofuryl group, a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), can be substituted] can be substituted) includes a pyridyloxy group (wherein, in the pyridine ring, 1 to 3 substituents selected from the group consisting of a pyridyl group [wherein, in the piper ring idine, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a phenoxy group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cß alkyl group substituted with Cl-Cβ phenyl alkoxy (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a group Cl-Cβ alkyl substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cβ phenoxy alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms carbon in the alkyl part as described later (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, an alkyl group C 1 -C 6 substituted or unsubstituted halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted by halogen can be substituted) and a C 1 -C 6 alkyl group phenyl as described above (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted ] and a (d-2) piperadinyl group [wherein, in the piperadine ring, 1 to 3 substituents selected from the group consisting of a Cl-Cβ alkoxycarbonyl group as described above, a Cl-Cβ furyl alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl part as described later [wherein, in the furan ring, 1 to 3 phenyl group (wherein, in the phenyl ring, 1 to 5, preferable 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted], a C 1 -C 6 alkyl pyridyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl part as described later [wherein, in the pyridine ring, 1 to 3 substituents selected from the group consisting of of a furyl group and a phenyl group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cβ benzothienyl alkyl group having a straight or branched alkyl group can be substituted] containing 1 to 6 carbon atoms in the alkyl part as described later (wherein, in the benzothiophene ring, 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or not substituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a C2-C6 alkenyl group phenyl having a straight or branched alkenyl group containing 2 to 6 carbon atoms and having 1 to 3 double bonds, and including both trans and cis forms as described later (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, an alkyl group Cl- Cβ substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cβ benzofuryl alkyl group having a straight or branched alkyl group which contains 1 to 6 carbon atoms in the alkyl part as described later [where, in the benzofuran ring, 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] , a benzofuryl C2-C6 alkenyl group having a straight or branched alkenyl group containing 2 to 6 carbon atoms in the alkenyl part and having 1 to 3 double bonds, and including both trans and cis forms as described later (wherein, in the benzofuran ring, 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can to be substituted), a Cl-Cβ thiazolyl alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl moiety as described later [en- of, on the thiazole ring, 1 to 2 phenyl groups (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or not substituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cβ phenoxy alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl part as described later (wherein, in the indole ring, 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cβ indolyl alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl part as described later ( wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted Cl-Cβ alkoxy group or not substituted with halogen can be substituted) and a Cl alkyl group up to Cß phenyl (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a benzofuryl group, a halogen atom, a group substituted or unsubstituted Cl-Cβ alkyl with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted], for example, a 2-pyridyloxy group, 3-pyridyloxy group, 4-pyridyloxy, 3- (1-piperidyl) -2-pyridyloxy group, 2- (4-piperidyl) -3-pyridyloxy group, 4- (2-piperidyl) -3-pyridyloxy group, 5- (3-piperidyl) group ) -2-pyridyloxy, group 2, 4-di (1-piperidyl) -3-pyridyloxy, gru 2- (1-piperidyl) -4- (2- (2-fluorophenoxy) -1-piperidyl] -3-pyridyloxy, group 2, 4, β-tri (1-piperidyl) -3-pyridyloxy, group 2- (4-phenoxy-1-piperidyl) -3-pyridyloxy, 2- (2,4-diphenoxy-1-piperidyl) -3-pyridyloxy group, 3- (2,4,6-triphenoxy-1-piperidyl) - 4-Pyridyloxy, 4- (2- (2-fluorophenoxy) -1- piperidyl] -2-pyridyloxy group, 5- (3- (3-fluorophenoxy) -2-piperidyl] -3-pyridyloxy group 6- ( 4- (4-fluorophenoxy) -3-piperidyl] -4-pyridyloxy, 2- (2- (2-chlorophenoxy) -4-piperidyl] -3-pyridyloxy group, 3- (3- (3-chlorophenoxy) - group 5-piperidyl] -4-pyridyloxy, 4- (4- (4-chlorophenoxy) -5-piperidyl] -4-pyridyloxy group, 5- (5- (2-bromophenoxy) -2-piperidyl] -3-pyridyloxy group , 2- (6- (3-bromophenoxy) -3-piperidyl] -4-pyridyloxy group, 2- (4- (4-bromophenoxy) -1-piperidyl] -2-pyridyloxy group, 3- (3- ( 2, 3-dichlorophenoxy) -2-piperidyl] -4-pyridyloxy, 3- (4- (3,4-dichlorophenoxy) -3-piperidyl] -4-pyridyloxy group, 4- (3- (2, 4- dichlorophenoxy) -4-piperidyl] -2-pyridyloxy group 5- (2- (3, 4, 5-trichlorophenoxy) -3-piperidyl] -2-pyridyloxy, group 6- (6- (2,4,6-trichlorophenoxy) -2-piperidyl] -3-pyridyloxy, 2- (3- (2, 3, 4, 5, 6-pentafluorophenoxy) -1-piperidyl group] 3-pyridyloxy, 4- (4- (2-methylphenoxy) -1-piperidyl] -2-pyridyloxy group, 3- (5- (3-methylphenoxy) -2-piperidyl] -2-pyridyloxy group 5- (6- (4-methylphenoxy) -3-piperidyl] -3-pyridyloxy, 2- (l- (2-ethylphenoxy) -4-piperidyl] -4-pyridyloxy group, 2- (2- (3-ethylphenoxy) group) -1-piperidyl] -3-pyridyloxy, 3- (3- (4-ethylphenoxy) -2-piperidyl] -4-pyridyloxy group, 4- (4- (4-n-propylphenoxy) -3-piperidyl] - group 2-pyridyloxy, 5- (5- (4-tert-butylphenoxy) -4-piperidyl] -3-pyridyloxy group, 6- (2- (4-n-butylphenoxy) -3-piperidyl] -2-pyridyloxy group, 2- (L- (2-trifluoromethylphenoxy) -2-piperidyl] -4-pyridyloxy group, 3- (2- (3-trifluoromethylphenoxy) -1-piperidyl] -4-pyridyloxy group, 4- (3- (4) group -trifluoromethylphenoxy) -1-piperidyl] -2-pyridyloxy, 5- (1- (2-pentafluoroethylphenoxy) -4-piperidyl] -3-pyridyloxy group, 6- (1- (3-pentafluoroethylphenoxy-4-piperidyl) - 2-pyridyloxy, gr upo 2- (4- (2,3-dimethylphenoxy-1-piperidyl) -3-pyridyloxy, 3- (1- (3,4,5-trimethylphenoxy-4-piperidyl) -2-pyridyloxy group 4- ( 1- (4-n-Pentylphenoxy-4-piperidyl] -3-pyridyloxy, 5- (4- (4-n-hexylphenoxy-1-piperidyl) -2-pyridyloxy group, β- (4- (2-methoxyphenoxy) group -1-piperidyl] -2-pyridyloxy, 2- (1- (3-methoxy-phenoxy-4-piperidyl) -4-pyridyloxy group, 3- (1- (4-methoxyphenoxy-4-piperidyl) -2-pyridyloxy group, 4- (2- (2-ethoxyphenoxy-3-piperidyl) -2-pyridyloxy group, 5- (3- (3-ethoxyphenoxy-4-piperidyl) -3-pyridyloxy group, 2- (4- (4-ethoxyphenoxy) group -5-piperidyl] -4-pyridyloxy, 2- (3- (4-n-propoxyphenoxy) -2-piperidyl] -4-pyridyloxy group, 3- (2- (4-tert-butoxyphenoxy) -1-piperidyl] - 4-pyridyloxy, 4- (1- (4-n-butoxyphenoxy-2-piperidyl) -2-pyridyloxy group, 5- (2- (2-trifluoromethoxyphenoxy) -3-piperidyl] -2-pyridyloxy group, group 6 (3- (3-trifluoromethoxyphenoxy) -4-piperidyl] -2-pyridyloxy, 6- (4- (4-trifluoromethoxyphenoxy) -3-piperidyl] -2-pyridyloxy group, 2- (3- (2-pent afluoroethoxyphenoxy) -2-piperidyl] -3-pyridyloxy, 3- (4- (4-pentafluoroethoxyphenoxy) -1-piperidyl] -2-pyridyloxy group, 4- (1- (2,3-dimethoxyphenoxy) -4-piperidyl group ] -2-pyridyloxy, 5- (4- (3,4) -trimetoxyphenoxy) -1-piperidyl] -3-pyridyloxy group, 6- (4- (4-n-pentyloxy-phenoxy) -1-piperidyl] - 3-Pyridyloxy, 5- (4- (4-n-hexyloxyphenoxy) -1-piperidyl] -3-pyridyloxy group, 2- (4- (4-trifluoromethylbenzyloxymethyl) -1-piperidyl] -5-pyridyloxy group, 2 - (4-trifluoromethoxybenzyl-1-piperidyl) -5-pyridyloxy, 2- (4- (4-chlorobenzyl) -1-piperazinyl] -5-pyridyloxy group, 2- (4- (4-trifluoromethylbenzyl) -1- group piperidyl] -5-pyridyloxy, 2- (4- (4-chlorobenzyloxymethyl) -1-piperazinyl] -5-pyridyloxy group, 4- (4-fluorobenzyl-1-piperadinyl) -β-pyridyloxy group, 4-phenoxy group) 3- (4- (4-trifluoromethoxybenzyloxymethyl) -1-piperidyl] -2-pyridyloxy, 2- (4-tert-butoxycarbonyl- (1-, 2- or 3-) piperadinyl] - (3-, 4-, 5- or 6-) pyridyloxy, 2- (4- (4 - ((2-, 3-, 4-, 5-, 6- or 7-) benzofur group il] benzyl) - (1-, 2- or 3-) piperadinil] - (3-, 4-, 5- or 6-) pyridyloxy, group 2- (4- (3 - ((2- or 3-) furyl] pyridylmethyl) - (1-, 2- or 3-) piperadinyl] - (3-, 4-, 5- or 6-) pyridyloxy, 2- (4- (2- (4-trifluoromethoxyphenyl) pyridylmethyl] - group (1-, 2- or 3-) piperadinil) - (3-, 4-, 5- or 6-) pyridyloxy, 2- (4- (2- (3-chloro-4-fluorophenyl) pyridylmethyl] - group ( 1-, 2- or 3-) piperadinil) - (3-, 4-, - or 6-) pyridyloxy, 2- (4- (5-trifluoromethyl- (2-, 3-, 4-, 6- or 7-) -benzofurylmethyl] - (1-, 2- or 3-) piperadinil) - (3-, 4-, 5- or 6-) pyridyloxy, 2- (4- (6-trifluoromethyl- ( 2. 3. 4-, - or 7-) benzofurylmethyl] - (1-, 2- or 3-) -piperadinyl) - (3-, 4-, 5- or 6-) pyridyloxy, 2- (4- (5-chloro- ( 2-, 3-, 4-, 6- or 7-) benzothienylmethyl] - (1-, 2- or 3-) piperadinil) - (3-, 4-, 5- or 6-) pyridyloxy, group 2- ( 4- (6-chloro- (2-, 3-, 4-, 5- or 7 -) - benzofurylmethyl] - (1-, 2- or 3-) piperadinil) - (3-, 4-, 5- or 6-) Pyridyloxy, 2- (4- (5-trifluoromethoxy- (2-, 3-, 4-, 6- or 7-) benzofurylmethyl] - (1-, 2- or 3-) -piperadinyl) - ( 3-, 4-, 5- or 6-) pyridyloxy, 2- (4- (3- (4-trifluoromethylphenyl) -2-propenyl] - (1-, 2- or 3-) piperadinyl) pyridyloxy group 2 - (4- (3- (3, 4-dichlorophenyl) -2-propenyl] - (1-, 2- or 3-) piperadinil) -pyridyloxy, 2- (4- (3- (4-chlorophenyl) - 2-propenyl] - (1-, 2- or 3-) piperadinyl) pyridyloxy, 2- (4- (3- (6-trifluoromethyl- (2-, 3-, 4-, 5- or 7-) benzofuryl group ] -2-propenyl) - (1-, 2- or 3-) piperadinil] pyridyloxy, group 2- (4- (3- (5-chloro- (2-, 3-, 4-, 5- or 7- ) benzofuryl] -2-propenyl) - (1-, 2- or 3-) piperadinyl] pyridyloxy, group 2- (4 - (5-chloro- (2-, 3-, 4-, 6- or 7-) benzofurylmethyl] - (1-, 2- or 3-) piperadinil) - (3-, 4-, 5- or 6-) ) pyridyloxy, 2- (4- (2- (4-trifluoromethylphenyl) - (4- or 5-) -thiazolylmethyl] - (1-, 2- or 3-) piperadinyl) pyridyloxy group 2- (4- ( 2- (4-trifluoromethoxyphenoxy) ethyl] - (l-, 2- or 3-) piperadinil) pyridyloxy, 2- (4- (3- (4-trifluoromethoxyphenyl) -2-propenyl] - (1-, 2-) group or 3 -) - piperadinyl) pyridyloxy, 2- (4- (5-trifluoromethoxy- (1-, 2-, 3-, 4-, β- or 7-) indolylmethyl] - (1-, 2- or 3) group -) piperadinil) pyridyloxy, 2- (4- (4-chlorophenoxymethyl) - (1-, 2- or 3-) piperidyl] - (3-, 4-, 5- or 6-) pyridyloxy group 2- ( 4- (2- (4-chlorophenyl) - (3-, 4- or 5-) furylmethyl] - (1-, 2- or 3-) piperadinil) -pyridyloxy, group 2- (4- (2- (2 -chloro-5-trifluoromethylphenyl) - (3-, 4- or 5-) furylmethyl] - (1-, 2- or 3-) piperadinil) pyridyloxy or the like. A 1,2,3,4-tetrahydroquinolyoxy group (wherein, in the 1, 2, 3, 4-tetrahydroquinoline ring, at least one selected from the group consisting of an oxo group, a phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] and an alkyl group Cl-Cβ phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted or unsubstituted Cl-Cβ alkoxy group with halogen can be substituted] can be substituted) includes a 1,2,3,4-tetrahydroquinolyoxy group [wherein, in the 1,2,3,4-tetrahydroquinoline ring, 1 to 3 substituents selected from the group consisting of oxo group, a phenyl group as described above (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted or unsubstituted Cl-Cβ alkoxy group halogen can be substituted) and a Cl-Cβ phenyl alkyl group as described above (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, an alkyl group Cl -Cβ substituted or unsubstituted with halogen and a substituted or unsubstituted C 1 -C 6 alkoxy group with halogen can be substituted), for example, a 1, 2, 3, 4-tetrahydro- (1-, 2) group -, 3-, 4-, 5-, 6-, 7- or 8-) quinolyloxy, group 1- (4-trifluoromethylbenzyl) -2-oxo-l, 2, 3, 4-tetrahydro-6-quinolyoxy group 1- (4-trifluoromethoxybenzyl) -2-oxo-l, 2, 3, 4-tetrahydro-6-quinolyloxy, l- (4-chlorobenzyl) -2-oxo-l, 2, 3, 4-tetrahydro-6 group -qu inolyloxy, 1- (4-trifluoromethylbenzyl) -1,2,3,4-tetrahydro-6-quinolyloxy group, 1- (4-trifluoromethoxybenzyl) -1,2,3,4-tetrahydro-6-quinolyoxy group 1- (4-chlorobenzyl) -1,2,3,4-tetrahydro-β-quinolyloxy group 1- (4-chlorophenyl) -1,2,3,4-tetrahydro-6-quinolyloxy group 1- (4-trifluoromethoxyphenyl) ) -1, 2, 3, 4-tetrahydro-6-quinolyoxy, 1- (4-trifluoromethylphenyl) -1,2,4,4-tetrahydro-β-quinolyoxy group, l- (3,4-dichlorobenzyl) - 1, 2, 3, 4-tetrahydro-6-quinolyloxy, group 1- (3,4-di (trifluoromethoxy) benzyl] -1,2,3,4-tetrahydro-6-quinolyloxy, group 1- (4-chlorophenyl) ) -1, 2, 3, 4-tetrahydro-5-quinolyloxy, group 1- (4-trifluoromethoxyphenyl) -1, 2, 3, 4-tetrahydro-5-quinolyloxy, group 1- (4-trifluoromethylphenyl) -1, 2, 3, 4-tetrahydro-5-quinolyloxy, 1- (4-chlorobenzyl) -1,2,3,4-tetrahydro-5-quinolyloxy group, l- (4-trifluoromethoxybenzyl) -1,2,3 group, 4-tetrahydro-5-quinolyloxy, 1- (4-trifluoromethylbenzyl) -1,2,3,4-tetrahydro-5-quinolyloxy group, group 1- (3, 4, 5-tr i (trifluoromethyl) benzyl] -1,2,3,4-tetrahydro-6-quinolyoxy, l-benzyl-4-phenyl-1,2,3,4-tetrahydro-6-quinolyoxy group, 1-phenyl-4 group , 6-dibenzyl-1, 2, 3, 4-tetrahydro-5-quinolyloxy, 4-phenyl-2-oxo-1,2,3,4-tetrahydro-l-quinolyoxy group or the like. A 1, 2, 3, 4-tetrahydronaphthyloxy group (wherein, in the 1, 2, 3, 4-tetrahydronaphthalene ring, at least one oxo group can be substituted) includes a 1,2,3,4-tetrahydronaphthyloxy group ( wherein, in the 1,2,3,4-tetrahydronaphthalene ring, 1 to 3 oxo groups can be substituted), for example, a group (1-, 2-, 5- or 6-) 1, 2, 3, 4-tetrahydronaphthyloxy, group 4-oxo-7-l, 2, 3, 4-tetrahydronaphthyloxy, group 1, 4-dioxo-6-l, 2, 3, 4-tetrahydronaphthyloxy, group 1, 2, 4-trioxo-5 -l, 2, 3, 4-tetrahydronaphthyloxy or the like. A 2H-chromenoxide group (wherein, in the 2H-chromene ring, at least one oxo group can be substituted) includes a 2H-chromenoxide group (wherein, in the 2H-chromene ring, at least one oxo group can be substituted ), for example, a 2H-chromenoxoxyl group, 2-oxo-2H-chromenzoxyl group or the like. A naphthyloxy group (wherein, in the naphthalene ring, at least one piperidyl group [wherein, in the piperidyl ring, at least one phenoxy group (wherein, in the phenyl ring, at least one selected from the group consisting of halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] can be substituted) includes a naphthyloxy group (wherein, in the naphthalene ring, 1 to 3 piperidyl groups as described above [wherein, in the piperidine ring, 1 to 3 phenoxy groups (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] can be substituted, for example, a group (1- or 2-) naphthyloxy, 6- (4- (4-trifluoromethoxyphenoxy) -1-piperidyl] -2-naphthyloxy group, 5- (1-piperidyl) -2-naphthyloxy group 2- (4-piperidyl) ) -3-naphthyloxy, 4- (2-piperidyl) -1- naphthyloxy group, 5- (3-piperidyl) -2-naphthyloxy group, 5,6-di (1-piperidyl) -1-naphthyloxy group 7 - (1-piperidyl) -6- (2- (2-fluorophenoxy) -1-piperidyl] -1-naphthyloxy, group 5,6,7-tri (1-piperidyl) -2-naphthyloxy, group 6- (4 -phenoxy-1-piperidyl) -3-naphthyloxy, 2- (2,4-diphenoxy-1-piperidyl) -4-naphthyloxy group, 3- (2,4,6-triphenoxy-1-piperidyl) -5- group Naphthyloxy, 4- (2- (2-fluorophenoxy) -1-piperidyl] -6-naphthyloxy group, 4- (3- (3-fluorophenoxy) -2-piperidyl] -2-naphthyloxy group 3- (4-) (4-fluorophenoxy) -3-piperidyl] -1-naphthyloxy, 5- (2- (2-chlorophenoxy) -4-piperidyl] -2-naphthyloxy group, β- (3- (3-chlorophenoxy) -5- group) piperidyl] -1-naphthyloxy, 4- (4- (4-chlorophenoxy) -2-piperidyl] -2-naphthyloxy group, 5- (5- (2-bromophenoxy) -2-piperidyl] -3-naphthyloxy group 6- (6- (3-bromophenoxy) -3-piperidyl] -4-naphthyl xi, group 6- (4- (4-bromophenoxy) -1-piperidyl] -2-naphthyloxy, group 3 - (3- (2,3-dichlorophenoxy) -2-piperidyl] -4-naphthyloxy, group 6- - (4- (3,4-dichlorophenoxy) -3-piperidyl] -1-naphthyloxy, group 4 - (3- (2,4-dichlorophenoxy) -4-piperidyl] -2-naphthyloxy, group 5- (2 - (3,4,5-trichlorophenoxy) -3-piperidyl] -2-naphthyloxy, group 6- (6- (2,4,6-trichlorophenoxy) -2-piperidyl] -3-naphthyloxy, group 2- (3 - (2,3,4,5,6-pentafluorophenoxy) -1-piperidyl] -3-naphthyloxy group 4- (4- (2-methylphenoxy) -1-piperidyl] -2-naphthyloxy, group 3- (5- (3-methylphenoxy) -2-piperidyl] -2-naphthyloxy, group 5- (6- (4- methylphenoxy) -3-piperidyl] -3-naphthyloxy, group 6- (1- (2-ethylphenoxy) -4-piperidyl] -4-naphthyloxy, 2- (2- (3-ethylphenoxy) -1-piperidyl] - 3-naphthyloxy, 3- (3- (4-ethylphenoxy) -2-piperidyl] -4-naphthyloxy group, 4- (4- (4-n-propylphenoxy) -3-piperidyl] -2-naphthyloxy group 5 - (5- (4-tert-butylphenoxy) -4-piperidyl] -1-naphthyloxy, 6- (2- (4-n-butylphenoxy) -3-piperidyl] -2-naphthyloxy group 2- (1-) (2-trifluoromethylphenoxy) -2-piperidyl] -4-naphthyloxy, 3- (2- (3-trifluoromethylphenoxy) -1-piperidyl] -4-naphthyloxy group, 4- (3- (4-trifluoromethylphenoxy) -1- group piperidyl] -2-naphthyloxy, 5- (1- (2-pentafluoroethylphenoxy) -4-piperidyl] -3-naphthyloxy group, β- (1- (3-pentafluoroethylphenoxy) -4-piperidyl] -2-naphthyloxy group 2- (4- (2,3-Dimethylphenoxy) -1-piperidyl] -1-naphthyloxy, 3- (1- (3,4-, 5-trimethylphenoxy) -4-piperidyl] -2-naphthyloxy group 4- (1- (4-n-pentylphenoxy) - 4-? Iperidyl] -1-naphthyloxy, group 5- (4- (4-n-hexylphenoxy) -1-piperidyl] -2-naphthyloxy, group 6- (4- (2-methoxyphenoxy) -1-piperidyl] - 2-naphthyloxy, 2- (l- (3-methoxyphenoxy) -4-piperidyl] -4-naphthyloxy group, 3- (l- (4-methoxyphenoxy) -4-piperidyl] -2-naphthyloxy group 4- ( 2- (2-ethoxyphenoxy) -3-? Iperidyl] -2-naphtyloxy, 5- (3- (3-ethoxyphenoxy) -4-piperidyl] -1-naphthyloxy group, 6- (4- (4-ethoxyphenoxy) group) -5-piperidyl] -4-naphthyloxy, 2- (3- (4-n-propoxyphenoxy) -2-piperidyl] -4-naphthyloxy group, 3- (2- (4-tert-butoxyphenoxy) -1-piperidyl group ] -4-naphthyloxy, 4- (l- (4-n-butoxyphenoxy) -2-piperidyl] -2-naphthyloxy group, 5- (2- (2-trifluoromethoxyphenoxy) -3-piperidyl] -2-naphthyloxy group, 6- (3- (3-trifluoromethoxyphenoxy) -4-piperidyl] -2-naphthyloxy group, 6- (4- (4-trifluoromethoxyphenoxy) -3-piperidyl] -2-naphthyloxy group 2- (3- (2) group -pentafluoroethoxyphenoxy) -2-piperidyl] -3-naphthyloxy, 3- (4- (4-pentafluoroethoxyphenoxy) -1-piperidyl] -2-naphthyloxy group, 4- (1- (2,3-dimethoxyphenoxy) -4- group piperidyl] -2-naphthyloxy, 5- (4- (3, 4, 5-trimethoxyphenoxy) -1-piperidyl] -1-naphthyloxy group 6- (4- (4-n-pentyloxyphenoxy) -1-piperidyl] -3-naphthyloxy group 5 - (4- (4-n-hexyloxyphenoxy) -1-piperidyl] -1-naphthyloxy or the like. A 1, 2, 3, 4-tetrahydroisoquinolyloxy group (wherein, in the 1, 2, 3, 4-tetrahydroisoquinoline ring, at least one selected from the group consisting of a C1-C6 alkoxycarbonyl group, a C1-C6 alkyl group phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be replaced] and a phenyl group [where, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted] to be substituted includes a 1,2,3,4-tetrahydroisoquinolyloxy group (wherein, in the 1,2,3,4-tetrahydroisoquinoline ring, 1 to 3 substituents selected from the group consisting of a Cl-Cß alkoxycarbonyl group, a group Cl-Cß phenyl alkyl (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen can be substituted) and a phenyl group as described above [wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of one atom and halogen, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], for example, a 1,2,3,4-tetrahydroisoquinolyl group (1-) , 2-, 3-, 4-, 5-, 6-, 7- or 8-) quinolyoxy, 2-tert-butoxycarbonyl-l, 2, 3, 4-tetrahydro-6-isoquinolyloxy group 2- (4 -chlorobenzyl) -1, 2, 3, 4-tetrahydro-6-isoquinolyloxy, 2- (4-trifluoromethoxybenzyl) -1, 2, 3, 4-tetrahydro-6-isoquinolyloxy group, 2- (4-trifluoromethylbenzyl) - 1,2,3,4-tetrahydro-6-isoquinolyoxy group 2-ethoxycarbonyl-4-benzyl-l, 2,3,4-tetrahydro-7-isoquinolyloxy group 1, 4,6-tribenzyl-2, 3,4-tetrahydro-8-isoquinolyoxy, group 1- (3,4-di (trifluoromethoxy) benzyl] -1,2,3,4-tetrahydro-6-isoquinolyoxy group 1- (3,4,5-tri) (trifluoromethyl) benzyl] -1,2,3,4-tetrahydro-6-isoquinolyoxy, 2- (4-trifluoromethoxyphenyl) - (1-, 3-, 4-, 5-, 6-, 7- or 8- isoquinolyloxy or the like. A phenyl group [wherein, in the phenyl ring, at least one piperidyl group (wherein, in the piperidine ring, at least one phenoxy group [wherein, in the phenyl group, at least one selected from the group consisting of halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen and a C1-C6 alkoxy group substituted or unsubstituted by halogen can be substituted] can be substituted) is substituted] includes, a phenyl group [wherein, in the phenyl ring, 1 to 3 piperidyl groups as described above (wherein, in the piperidine ring, 1 to 3 phenoxy groups [wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted) are, for example, a group 4- (1-piper idyl) phenyl, 3- (2-piperidyl) phenyl group, 4- (4- (4-trifluoromethoxyphenoxy) -1-piperidyl] phenyl group, 4- (4- (4-trifluoromethylphenoxy) -1-piperidyl] phenyl group, 4- (4- (4-chlorophenoxy) -1-piperidyl] phenyl group, 4- (4- (3,4-di (trifluoromethoxy) phenoxy-1-piperidyl]) phenyl group 4- (4- (3 , 4, 5-tri (trifluoromethyl) phenoxy-1-piperidyl]) phenyl, 4- (4- (2,4-dichlorophenoxy) -1-piperidyl] phenyl group, 4- (4- (2, 4, 6 -trifluorophenoxy) -1-piperidyl] phenyl, 2- (2,4,5-trifenoxy-1-piperidyl) phenyl group, 3- (1, 2-diphenoxy-4-piperidyl) phenyl group, 2, 4-di group (4-piperidyl) phenyl, group 2, 4,6-tri (3-piperidyl) phenyl or the like. A C 1 -C 6 alkyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of at least one piperidyl group (wherein, on the piperidine ring, a phenoxy group [wherein, on the phenyl ring , at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted] is substituted) and a group -NR24R25 (R24 represents a halogen atom or C1-C6 alkyl group.) R25 represents a C2-C6 alkenyl group phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted]) are substituted] includes a Cl-Cβ phenyl alkyl group as described above [wherein, on the phenyl ring, 1 to 3 substituents selected from the group consisting of 1 to 3 piperidyl groups as described above (wherein, on the ring piperidine, 1 to 3 phenoxy groups [wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] are substituted) and a group -NR24R25 (R24 represents a halogen atom or Cl-Cß alkyl group.) R25 represents a C2-C6 alkenyl group phenyl as described later [a group consisting of 1 or 2 phenyl groups unsubstituted or substituted by 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or not substituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen]) are substituted and an alkenyl group containing 2 to 6 carbon atoms and having 1 to 3 double bonds.], eg, a 4- group (l-piperidyl) benzyl, 2,4-di (4-piperidyl) benzyl, 2,4,6-tri (2-piperidyl) benzyl group, 4- (4- (4-trifluoromethoxyphenoxy) -1-piperidyl group] benzyl, group 4- (N-methyl-N- (4-trifluoromethoxycinnamyl) amino] benzyl, 4- (N- (4-trifluoromethoxycinnamyl) amino] benzyl group, 4- (4- (4-trifluoromethylphenoxy) -1- group piperidyl] benzyl, 4- (4- (4-chlorophenoxy) -1-piperidyl] benzyl group, 4- (4- (3,4-di (trifluoromethoxy) phenoxy] -1-piperidyl) benzyl group 4- ( 4- (2,4,6-tri (tri fluoromethyl) phenoxy] -1-piperidyl) benzyl, 4- (4- (2,4-dichlorophenoxy) -1-piperidyl] benzyl group, 4- (4- (2,4,6-trifluorophenoxy) -1-piperidyl group ] benzyl, 3- (2,4-diphenoxy-3-piperidyl) benzyl group, 2- (1, 2, 3-trifenoxy-4-piperidyl) benzyl group, 4- (N-methyl-N- (4- trifluoromethoxycinnamyl) amino] -3- (4- (4-trifluoromethoxyphenoxy) -1-piperodyl] benzyl or the like. A C1-C6 alkyl piperidyl group (wherein, in the piperidine ring, at least one phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group) substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) is substituted) includes a Cl-Cβ piperidyl alkyl group (wherein, in the piperidine ring, 1 to 3 phenyl groups as described above (wherein, on the phenyl ring, 1 or 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) are substituted), for example, a (4-phenyl-1-piperidyl) methyl group, 2- (3-phenyl-2-piperidyl) ethyl group, 3- (2-group phenyl-3-piperidyl) propyl, 4- (1-phenyl-4-piperidyl) butyl group, 5- (4-phenyl-1-piperidyl) pentyl group, β- (1-phenyl-2-piperidyl) hexyl group, l- (4-trifluoromethoxyphenyl) -4-piperidylmethyl group, l- (4- trifluoromethylphenyl) - group 4-piperidylmethyl, 1- (3-methoxyphenyl) -4-piperidylmethyl group, 1- (2-methylphenyl) -4-piperidylmethyl group, 1- (4-chlorophenyl) -4-piperidylmethyl group, group 1- (3, 4) -di (trifluoromethoxy) phenyl] -4-piperidylmethyl, 1- (2,4,6-tri (trifluoromethyl) phenyl] -4-piperidylmethyl group, 1- (3,4-dimethylphenyl) -4-piperidylmethyl group, group 1 - (2,4,6-trimethoxyphenyl) -4-piperidylmethyl, l- (3,4-dichlorophenyl) -4-piperidylmethyl group, l- (2,4,6-tribromophenyl) -4-piperidylmethyl group, group (1), 2,6-triphenyl-4-piperidyl) methyl, (2,4-diphenyl-1-piperidyl) methyl group or the like. A C1-C6 alkyl piperadinyl group (wherein, in the piperadine ring, at least one phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted) includes a C 1 -C 6 alkyl piperadynyl group (wherein, in the piperadine ring, 1 to 3 phenyl groups as described above [wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-6 alkoxy group C6 substituted or unsubstituted with halogen can be substituted] can be substituted), for example, a 1-piperadinylmethyl group, 1- (2-piperadinyl) ethyl group, 2- (1-piperadinyl) ethyl group, 3- (1 -piperadinil) propyl, group 2- (l-piper adynyl) propyl, 4- (2-piperadinyl) butyl group, 5- (2-piperadinyl) pentyl group, 4- (1-piperadinyl) pentyl group, group 6- (1-piperadinyl) hexyl, 2-methyl-3- (1-piperadinyl) propyl group, 1-l-dimethyl-2- (1-piperadinyl) ethyl group, (4-phenyl-1-piperadinyl) methyl group , group (2,4-diphenyl-1-piperadinyl) methyl, (2,4,5-triphenyl-1-piperadinyl) ethyl group, (4- (4-trifluoromethoxyphenyl) -1-piperadinyl] methyl group (4) - (4-trifluoromethylphenyl) -1-piperadinyl] methyl, group (4- (4-chlorophenyl) -1-piperadinyl] methyl, group (4- (2,4-dichlorophenyl) -1-piperadinyl] methyl, group (4 - (2,4,6-trifluorophenyl) -1-piperadinyl] methyl, group (2,4-di (trifluoromethyl) phenyl-1-piperadinyl] methyl, group (2,4,6-tri (trifluoromethoxy) phenyl-1) -piperadinyl] methyl or the like A C1-C6 alkyl piperidyl group (wherein, in the piperidine ring, at least one phenoxy group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom , a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can to be substituted] can be substituted) includes a C1-C6 alkyl piperidyl group (wherein, in the piperidine ring, 1 to 3 phenoxy groups as described above [wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted), for example, a 1-piperidylmethyl group, 2- (2-piperidyl) ethyl group, 3- (3-piperidyl) propyl group, 4- (4-piperidyl) butyl group, 5- (1-piperidyl) pentyl group, 6- (2-group -piperidyl) hexyl, l- (4-trifluoromethoxyphenoxy) -4-piperidylmethyl group, l- (4-trifluoromethylphenoxy) -4-piperidylmethyl group, 2-methyl-3- (piperidin-1-yl) propyl group, group 1, l-dimethyl-2- (piperidin-1-yl) ethyl, 1- (4-chlorophenoxy) -4-piperidylmethyl group, 1- (3,4-di (trifluoromethoxy) phenoxy] -4-piperidylmethyl group ilo, group 1- (2,4,6-tri (trifluoromethoxy) phenoxy] -4-piperidylmethyl group 1- (3,4-dichlorophenoxy) -4-piperidylmethyl, 1- (2,4,6-tribromophenoxy) -4-piperidylmethyl group, (1, 2, 6-trifenoxy-4-piperidyl) methyl group, (2) , 4-diphenoxy-1-piperidyl) methyl or the like. A thiazolyl group [wherein, in the thiazole ring, at least one selected from the group consisting of a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group Cl-Cβ substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cβ piperadinyl alkyl group (wherein, in the piperadine ring, at least one phenyl group [in where, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] may be substituted) and a Cl-Cβ piperidyl alkyl group (wherein, in the piperidine ring, at least one phenoxy group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl alkyl group -Cβ substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted) can be substituted] includes a thiazolyl group [wherein, in the thiazole ring, 1 or 2 substituents selected from the group consisting of a phenyl group as described above (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted Cl-Cβ alkyl group or not substituted by halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cβ piperadynyl alkyl group as described above (wherein, in the piperadine ring, 1 to 3 phenyl group [wherein, in the phenyl group, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted or unsubstituted Cl-Cβ alkoxy group halogen can be substituted] can be substituted) and a Cl-Cβ piperidyl alkyl group as described above (wherein, in the piperidine ring, 1 to 3 phenoxy groups [wherein, in the phenyl group, 1 to 5, preferably 1 up to 3 substituents selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted) can be substituted ], for example, a (2-, 4- or 5-) thiazolyl group, 2- (4-trifluoromethoxyphenyl) -5-thiazolyl group, 2- (4- (4-trifluoromethoxyphenyl) -l-piperadinyl] methyl group 5-thiazolyl, 2- (4- (4-trifluoromethyl group xifenoxi) -l-piperidyl] methyl-5-thiazolyl, 2- (2,4-di (trifluoromethoxy) phenyl) -5-thiazolyl group, 2- (4- (2,4-di (trifluoromethoxy) phenyl) group - 1-piperadinyl) methyl-5-thiazolyl, 2- (4- (2,4-di (trifluoromethoxy) phenoxy) -1-piperadinyl) methyl-5-thiazolyl group, 2- (4-trifluoromethylphenyl) -5-thiazolyl group , 2- (4- (4-trifluoromethylphenoxy) -l-piperidyl) methyl-5-thiazolyl group, 2- (4- (4-trifluorothylfenyl) -l-piperidyl) methyl-5-thiazolyl group, 2- (2-group , 4,6-tri (trifluoromethyl) phenyl)) -5-thiazolyl, 2- (4- (2,4,6-tri- (trifluoromethyl) phenyl) -l-piperadinyl) methyl-5-thiazolyl group 2- (2- (2,4,6-tri (trifluoromethyl) phenoxy] -1- piperidyl) methyl-t-thiazolyl, 2- (4- (2,4,6-tri (trifluoromethyl) phenoxy) -l-piperidyl group ) methyl-5-thiazole) 2- (4-chlorophenyl) -5-thiazolyl, 2- (4- (4-chlorophenyl) -1-piperadinyl] methyl-5-thiazolyl group, 2- (4- (2- chlorophenoxy) -1-piperidyl] methyl-5-thiazolyl, 2- (2,4-dichlorophenyl) -5-thiazolyl group, 2- (4- (2,4-dichlorophenyl) -l-piperadiyl group nyl) methyl-5-thiazolyl, 2- (2- (2,4-dichlorophenyl) -1-piperadinyl] methyl-t-thiazolyl group, 2- (4- (2,4-dichlorophenoxy) -l-piperidyl group] methyl-5-thiazolyl, 2- (2,4,6-trifluorophenyl) -5-thiazolyl group, 2- (4- (2,4,6-trifluorophenyl) -l-piperadinyl] methyl-5-thiazolyl group, group 2- (4- (2,4,6-trifluorophenoxy) -l-piperidyl] methyl-5-thiazolyl, 2- (2,4-diphenoxy-1-piperidyl) methyl-5-thiazolyl group, group 5- (2 , 4,5-triphenoxy-1-piperidyl) methyl-2-thiazolyl, 5- (2,4-diphenyl-1-piperadinyl) methyl-2-thiazolyl group, 2- (2,4,5-triphenyl-1) group -piperadinyl) methyl-4-thiazolyl, 4- (l-piperidyl) -2- (1-piperadinyl) -5-thiazolyl group or the like. A benzooxazolyloxy group (wherein, in the benzooxazole ring, at least one selected from the group consisting of a piperazinyl group [wherein, in the piperadine ring, 1 to 3 groups selected from the group consisting of a C1-C6 alkyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) and a C2-C6 alkenyl group phenyl having a straight or branched alkenyl group containing 2 to 6 carbon atoms in the alkenyl part and having 1 to 3 double bonds and including both trans and cis forms as described further late (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a group or Cl-Cβ alkoxy substituted or unsubstituted with halogen can be substituted), a piperidyl group (wherein, in the piperidine ring, 1 to 3 substituents selected from the group consisting of a Cl-Cβ phenyl alkyl group as described above [wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] and an amino group [wherein, in the amino group, 1 or 2 substituents selected from the group which consists of a C1-C6 alkyl group as described above and a phenyl group as described above (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] can be substituted) and a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted (substituted) includes a benzooxazolyloxy group (wherein, in the benzooxazole ring, 1 to 3 substituents selected from the group consisting of a piperadinyl group as described above [wherein, in the piperadine ring, at least one selected from the group which consists of a Cl-Cß phenyl alkyl group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) and a C2-C6 alkenyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted], a piperidyl group (wherein, in the piperidine ring, at least one selected from the group consisting of a C1-C6 alkyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted C1-C3 alkyl group or not substituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] and an amino group [wherein, in the amino group, at least one selected from the group consisting of a Cl-Cß alkyl group and a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted by halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] can be substituted) and a phenyl group as described above (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen can be substituted) are substituted), for example, a 2- (4 ((4-trifluoromethoxybenzyl) group) -1-piperadinyl] -6-benzooxazolyloxy, 2-phenyl-5-benzooxazolyloxy group, 2- (4-chlorophenyl) -5-benzooxazolyloxy group, 2- (4- (4-trifluoromethylbenzyl) -1-piperadinyl] -6 group - benzooxazolyloxy, 2- (4- (4-chlorobenzyl) -1-piperadinyl] -6-benzooxazolyloxy group, 2- (4- (2,4,6-tri (trifluoromethoxy) benzyl] -1-piperadinyl group) -6 -benzooxazolyloxy, 2- (4- (2,4-di (trifluoromethyl) benzyl] -1-piperadinyl) -6-benzooxazolyloxy group, 2- (4- (2,4-dichlorobenzyl) -1-piperadinyl] -6 group -benzooxazolyloxy, 2- (4- (2,4,6-trifluorobenzyl) -1-piperadinyl] -6-benzooxazolyloxy group, 2- (4-benzyl-l-piperadinyl) -4-benzooxazolyloxy group 2- (2) , 4-dibenzyl-1-piperadinyl) -7-benzooxazolyloxy, 2- (2,4,6-tribenzyl-1-piperadinyl) -6-benzooxazolyloxy group, g 2- (4-trifluoromethoxyphenyl) -5-benzooxazolyloxy group 2- (4-trifluoromethylphenyl) -5-benzooxazolyloxy group, 2- (2,4-dibromophenyl) -5-benzooxazolyloxy group, 2- (2,4,6-trichlorophenyl) -5-benzooxazolyloxy group, 2- (2,4,6-tri (trifluoromethoxy) phenyl] group 5-benzooxazolyloxy, 2- (2,4-di (trifluoromethyl) phenyl] -5-benzooxazolyloxy group, 4-phenyl-5- (1-piperadinyl) -2-benzooxazolyloxy group, 2, 4, 5-triphenyl-7 group -benzooxazolyloxy, 2- (4- (4-trifluoromethoxybenzyl) - (1-, 2- or 3-) piperidyl] - (2-, 4-, 5-, 6- or 7-) benzooxazolyloxy, 2- (4- (3- (4-trifluoromethylphenyl) -2-propenyl] - (1-) group , 2- or 3-) piperadinil) - (2-, 4-, 5-, 6- or 7-) benzooxazolyloxy, group 4- (N-methyl-N- (4-chlorophenyl) amino] - (1-, 2- or 3-) piperidyl] - (2-, 4-, 5-, 6- or 7-) benzooxazolyloxy or the like A benzoimidazolyloxy group (wherein, in the benzoimidazole ring, at least one selected from the group consisting of a Cl-Cß alkyl group, a phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and an alkoxy Cl group -Cβ substituted or unsubstituted with halogen can be substituted], a piperidyl group [wherein, in the piperidine ring, at least one phenoxy group (wherein, in the phenyl ring, at least one selected from the group consisting of one atom of halogen, a Cl-Cß alkyl group substituted or unsubstituted with halogen no and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted], a piperadinyl group [wherein, in the piperadine ring, at least one Cl-Cβ phenyl alkyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] and a Cl-Cß phenyl alkyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted) includes a benzoimidazolyloxy group (wherein, in the benzoimidazole ring, 1 to 3 substituents selected from the group consisting of a Cl-Cß alkyl group, a phenyl [wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or not substituted by halogen can be substituted], a piperidyl group as described above [wherein, in the piperidine ring, 1 to 3 phenoxy groups (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted), a piperadinyl group as described above [wherein, in the piperadine ring, 1 to 3 Cl-Cβ phenyl alkyl groups (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group which a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] and a Cl-Cβ phenyl alkyl group as described above [wherein, on the phenyl ring, 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted or unsubstituted Cl-Cβ alkoxy group halogen can be substituted] can be substituted), for example, a (1-, 2-, 4-, 5-, 6- or 7-) benzoimidazolyloxy group, 2-f-enyl-5-benzoimidazolyloxy group, group l- methyl-5-benzoimidazolyloxy, l-methyl-2-phenyl-5-benzoimidazolyloxy group, 2- (4-chlorophenyl) -5-benzoimidazolyloxy group, l-methyl-2- (4-chlorophenyl) -5-benzoimidazolyloxy group, group 1, 2-diphenyl-5-benzoy-idazolyloxy, group 1, 4-dimethyl-5-benzoimidazolyloxy, 1-methyl-2,6-difyl en-5-benzoimide group azolyoxy, 2- (4-trif luoromethylphenyl) -5-benzoimidazolyloxy group, l-methyl-2- (4-trifluoromethoxyphenyl) -5-benzoimidazolyloxy group, group 1, 2, 7-triflu enyl-5-benzoimidazolyloxy, group 1, 2,4-trimethyl-5-benzoimidazolyloxy, group 1 ethyl-2, ß-diphenyl-5-benzoimidazolyloxy, 2- (2,4-di (trifluoromethyl) phenyl] -5-benzoimidazolyloxy group, l-methyl-2- (2,4,6-tri (trifluoromethoxy) phenyl group ] -5-benzoimidazolyloxy, 2- (2,4-dichlorophenyl) -5-benzoimidazolyloxy group, 2- (2,4,6-trifluorofenyl) -5-benzoimidazolyloxy group, 2- (3-bromo-phenyl) -5 group -benzoimidazolyloxy, 2- (2-iodophenyl) -5-benzoimidazolyloxy group, 2- (4-trifluoromethoxyifenoxi- (1-, 2- or 3-) piperidyl- (1-, 4-, 5-6- or 7-) imidazolyloxy, group 1-benzyl-2- (4-trifluoromethoxybenzyl- (1-, 2- or 3-) piperadinyl] - (4-, 5-, 6-or -7) imidazolyloxy, group 1- (4-trifluoromethoxybenzyl) - (2-, 4-, 5-, ß- or 7-) imidazolyloxy or the like A 1, 2, 3, 4-tetrahydroisoquinolyl group (wherein, in ring 1, 2, 3, 4-tetrahydroisoquinoline, at least one selected from the group consisting of a group (ml) amino [wherein, in the amino group, at least one selected from the group consisting of a Cl-Cß alkyl group, a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) and a Cl-Cβ phenyl alkyl group ( wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted ) can be selected] and a group (m-2) phenoxy [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a substituted C1-Cβ alkoxy group or not halogen-substituted can be substituted] can be substituted) includes a 1,2,3,4-tetrahydroisoquinolyl group (wherein, in the 1,2,3,4-tetrahydroisoquinoline ring, 1 to 3 substituents selected from the group consisting of an amino group as described later [wherein, in the amino group, 1 or 2 substituents selected from the group consisting of a Cl-Cß alkyl group, a phenyl group (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) and an alkyl Cl group - Cß phenyl (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen can be substituted) can be substituted] and a phenoxy group as described above [wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted), for example, a group (1-, 2- , 3-, 4-, 5-, 6-, 7- or 8-) 1, 2, 3, 4-tetrahydroisoquinolyl, group 7- (N-methyl-N- (4-trifluoromethoxyphenyl) amino] -1 , 2, 3, 4-tetrahydro-2-isoquinolyl, group 7- (N-methyl-N- (4-trifluoromethoxybenzyl) amino] -1,2,3,4-tetrahydro-2-isoquinolyl, group 6- ( 4-trif luoromethoxif enoxi) -1, 2, 3, 4-tetrahydro-2-isoquinolyl, group 7- (N-methyl-N- (4-trif luoromethylphenyl) amino] -1, 2, 3, 4-tetrahydro -2-isoquinolyl, group 7- (N-methyl-N- (4-trifluoromethylbenzyl) amino] -1, 2, 3, 4-tetrahydro-2-isoquinolyl, group 6- (4-trif luoromethyl-enoxy) -1, 2, 3, 4-tetrahydro-2-isoquinolyl, group 7- (N-methyl-N- (4-chlorofenyl) amino] -1, 2, 3, 4-tetrahydro-2-isoquinolyl, group 7- ( N- (4-chlorofenyl) amino] -1,2,3,4-tetrahydro-2-isoquinolyl, group 7- (N-methyl-N- (4-chlorobenzyl) amino] -1, 2, 3, 4 -tetrahydro-2-isoquinolyl, group 7- (N- (4-chlorobenzyl) amino] -1,2,3,4-tetrahydro-2-isoquinolyl, group 6- (4-chlorophenoxy) -l, 2,3, 4-tetrahydro-2-isoquinolyl, group 7- (N-methyl-N- (2,4-di (trifluoromethoxy) phenyl] amino) -1,2,3,4-tetrahydro-2-isoquinolyl, group 7- ( N-methyl-N- (2,4,6-tri (trifluoromethoxy) benzyl] amino) -1,2,3,4-tetrahydro-2-isoquinolyl group 6- (2,4-di (trifluoromethoxy) phenoxy] -1, 2, 3, 4-tetrahydro-2-isoquinolyl, group 7- (N-methyl-N- (2,4,6-tri (trifluoromethyl) phenyl] amino) -1,2,3,4-tetrahydro -2-isoquinolyl, group 7- (N-methyl-N- (2,4-di (trifluoromethyl) benzyl] amino) -1,2,3,4-tetrahydro-2-isoquinolyl, group 6- (2, 4 , 6-tri (trifluoromethyl) -phenoxy] -l, 2,3,4-tetrahydro-2-isoquinolyl, group 7- (N-methyl-N- (2,4-dibromofenyl) amino] -1,2,3,4-tetrahydro-2-isoquinolyl, group 7- (N-methyl-N- (2,3-diiodobenzyl) ) amino] -1,2,3, 4-tetrahydro-2-isoquinolyl, group 6- (2,4,6-trif luorofenoxi) -1,2,3,4-tetrahydro-2-isoquinolyl, group 7 amino-6-phenoxy-1, 2,3,4-tetrahydro-2-isoquinolyl, 4,5,6-trifenoxyl-l, 2,3,4-tetrahydro-7-isoquinolyl group or the like. A C1-C6 alkoxy group substituted by 2 phenyl groups [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and an alkoxy group C 1 -C 6 substituted or unsubstituted with halogen can be substituted] includes a C 1 -C 6 alkoxy group substituted by 2 phenyl groups (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen and a C1-C6 alkoxy group substituted or unsubstituted by halogen can be substituted), for example, a 1,1-diphenylmethoxy group, group 1, 2- diphenylethoxy, group 3, 3-diphenylpropoxy, 3,4-diphenylbutoxy group, 3-diphenylpentyloxy group, 4,6-diphenylhexyloxy group, 1-di (4-trifluoromethoxyphenyl) methoxy group, 1- (2-fluorophenyl) group ) -1- (3-fluorophenyl) methoxy, group l- (4-fluorophenyl) -1- (2-chlorof enyl) methoxy, 1- (3-chlorophenyl) -1- (4-chlorophenyl) methoxy group, 1- (2-bromophenyl) -1- (3-bromophenyl) methoxy group, 1- (4-bromophenyl) -2 group - (2-iodophenyl) ethoxy, 3- (3-iodophenyl) -3- (4-iodophenyl) propoxy group, 1- (2, 3-difluorophenyl) -1- (3,4-difluorophenyl) methoxy group, group 4 - (3,5-difluorophenyl) -4- (2,4-difluorophenyl) butoxy, 5- (2,6-difluorophenyl) -5- (2,3-dichlorophenyl) pentyloxy group 6- (3, 4-) dichlorophenyl) -6- (3,5-dichlorophenyl) hexyloxy, 1- (2,4-dichlorophenyl) -1- (2, β-dichlorophenyl) methoxy group, 1- (3, 4, 5-trifluorophenyl) -1 group - (3,4, 5-trichlorophenyl) methoxy, group l- (2,3,4,5, β-pentafluorophenyl) -1- (2,4,6-trimethylphenyl) methoxy, group 1- (4-n- butylphenyl) -1- (2,4-dimethylphenyl) methoxy, 1- (3, 5-ditrifluoromethylphenyl) -1- (4-n-butoxyphenyl) methoxy group, 1- (2,4-dimethoxyphenyl) -1- group ( 2, 3-dimethoxyphenyl) methoxy, 1- (2,4,6-trimethoxyphenyl) -1- (3,5-ditrifluoromethoxyphenyl) -methoxy group, 1- (3-chloro-4-methoxyphenyl) -1- (2 -chloro-4- trifluorometho xyphenyl) methoxy, 1- (3-methyl-4-fluorophenyl) -1- (2-bromo-3-trifluoromethylphenyl) methoxy group, l- (2-ethylphenyl) -1- (3-methylphenyl) methoxy group l - (2-pentafluoroethylphenyl) -1- (3-pentafluoroethylphenyl) -methoxy, 1- (2-isopropylphenyl) -1- (2-tert-butylphenyl) methoxy group, 1- (2-sec-butylphenyl) -1- group (2-n-heptafluoropropylphenyl) methoxy, 1- (4-pentylphenyl) -1- (4-hexylphenyl) methoxy group, l- (2-methoxyphenyl) -1- (2,6-dimethoxyphenyl) methoxy group l- (2-pentafluoroethoxyphenyl) -1- (isopropoxyphenyl) methoxy, group l- (2-tert-butoxyphenyl) -1- (2-sec-butoxyphenyl) methoxy, group 1- (2-n-heptafluoro-propoxyphenyl) -1- (4-n-pentoxyphenyl) methoxy, group 1, 1-di (4-n-hexyloxyphenyl) methoxy or the like. A piperidyl group (wherein, in the piperidine ring, at least one selected from the group consisting of (n-1) a phenyl group [wherein, in the phenyl ring, at least one group -NR26R27 (R26 represents a hydrogen or Cl-Cß alkyl group R27 represents a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted by halogen can be substituted]) is substituted], (n-2) a group-W? NR28R29 [Wx represents an alkylene group Cl-Cß, R28 represents a hydrogen atom or alkyl group Cl-Cβ and R29 represents a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted by halogen and a Cl-C alco alkoxy group) Cß substituted or unsubstituted with halogen can be replaced) ], (n-3) a Cl-Cβ alkoxy group substituted by 2 phenyl groups [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or not substituted with halogen and a C1-Cß alkoxy group substituted or unsubstituted with halogen can be substituted] and (n-4) a Cl-Cß alkyl phenyl group [wherein, in the phenyl group ring, at least one phenyl group ( wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted ) is substituted] can be substituted) includes a piperidyl group (wherein, in the piperidine ring, 1 to 3 substituents selected from the group consisting of (n-1) a phenyl group [wherein, on the phenyl ring, 1 to 3 groups -NRNR26R27 (R2e represents a hydrogen atom or group for alkyl Cl-Cß. R 27 represents a phenyl group as described above [wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted]) are substituted], (n-2) a group-W? NR28R29 [Wi represents alkylene group Cl-Cß, R28 represents a hydrogen atom or a Cl-Cß alkyl group as described above and R29 represents a phenyl group as described above (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a group substituted or unsubstituted Cl-Cβ alkyl with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted)], (n-3) a Cl-Cβ alkoxy group substituted with 2 phenyl groups as described above [wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted Cl-Cβ alkoxy group or unsubstituted with halogen can be substituted] and (n-4) a Cl-Cß phenyl alkyl group as described later [wherein, in the phenyl group ring, 1 to 3 phenyl group (wherein, in the phenyl ring , 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen can be substituted) are substituted] can be substituted), for example, a (1-, 2-, 3- or 4-) piperidyl group, 4- (N-methyl-N- (4-trifluoromethoxyphenyl) amino] phenyl-1-piperidyl group , 4- (N- (4-trifluoromethoxyphenyl) -aminomethyl] -1-piperidyl group, 4- (N-methyl) group l-N- (4-trifluoromethoxyphenyl) aminomethyl] -1-piperidyl, group 4- (N-Ethyl-N- (4-trifluoromethoxyphenyl) aminomethyl] -1-piperidyl, 4- (1,1-di (4-trifluoromethoxyphenyl) -methoxy] -1-piperidyl group, group 4- (N -methyl-N- (4-trifluoromethylphenyl) amino] phenyl-1-piperidyl, 4- (N- (4-trifluoromethylphenyl) aminomethyl] -1-piperidyl group, 4- (N-methyl-N- (2, 4 -di (trifluoromethyl) phenyl] -aminomethyl) -1-piperidyl, group 4- (N-ethyl-N- (2,4,6-tri (trifluoromethoxy) phenyl] aminomethyl) -1-piperidyl, group 4- (1 , 1-di (4-trifluoromethylphenyl) methoxy-1-piperidyl, 4- (N-methyl-N- (4-chlorophenyl) amino] -phenyl-1-piperidyl group, 4- (N- (2, 4- dibromophenyl) -aminomethyl] -1-piperidyl, 4- (N-methyl-N- (2,4,6-trifluorophenyl) aminomethyl] -1-piperidyl group 4- (N-ethyl-N- (4-chlorophenyl) aminomethyl] -1-piperidyl, 4- (1,1-di (4-chlorophenyl) methoxy] -1-piperidyl group, 4- (N-methyl-) N- (2,4-dibromophenyl) amino] phenyl-1-piperidyl, 4- (1,1-di (2,4-dibromophenyl) methoxy] -1-piperidyl group, 4- (N-methyl-N-) group (2,4,6-trifluorophenyl) -amino] phenyl-1-piperidyl, 4- (1,1-di (2,4,6-trifluorophenyl) methoxy] -1-piperidyl group 4- (N-methyl) -N- (2,4-di (trifluoromethyl) phenyl] amino) phenyl-1-piperidyl, 4- (N-methyl-N- (2,4,6-tri (trifluoromethoxy) phenyl] amino) phenyl-1 group -piperidyl, 4- (1- (2,4-di (trifluoromethyl) phenyl] -1- (2,4,6-tri (trifluoromethoxy) phenyl] methoxy) -1-piperidyl group, 4- (N- ( 4-trifluoromethoxyphenyl) aminomethyl] -3- (N- (4-trifluoromethylphenyl) aminomethyl] -1-piperidyl, 3,4,6-tri (1,1-diphenylmethoxy) -1-piperidyl group, 4- (4- group phenylbenzyl) - (1-, 2- or 3-) piperidinyl or the like A C 1 -C 6 alkyl group substituted by 2 phenyl groups [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted] includes a C1-C6 alkyl group substituted by 2 groups phenyl [wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a substituted C1-C6 alkoxy group or unsubstituted with halogen can be substituted], for example, a 1, 1-diphenylmethyl group, 1,2-diphenylethyl group, 3, 3-diphenylpropyl group, 3,4-diphenylethyl group, 3, 5-diphenylpentyl group, group 4,6-diphenylhexyl, group 1, 1-di (4-trifluoromethoxyphenyl) methyl, group 1, 1-di (4-chlorophenyl) methyl, group 1- (2-fluorophenyl) -1- (3-fluorophenyl) methyl, 1- (4-fluorophenyl) -1- (2-chlorophenyl) methyl, 1- (3-chlorophenyl) -1- (4-chlorophenyl) methyl, group 1- (2-bromof) group enyl) -1- (3-bromophenyl) methyl, 1- (4-bromofenyl) -2- (2-iodophenyl) ethyl group, 3- (3-iodophenyl) -3- (4-iodophenyl) propyl group, Group 1- (2,3-difluorofenyl) -1- (3,4-difluorofenyl) methyl, 4- (3,5-difluorofenyl) -4- (2,4-difluorofenyl) butyl group , group 5- (2,6-difluorofenyl) -5- (2,3-dichlorofenyl) pentyl, 6- (3,4-dichlorofenyl) -6- (3,5-dichlorofenyl) hexyl group Group 1- (2,4-dichlorofenyl) -1- (2,6-dichlorofenyl) methyl, group 1- (3,4,5-trif luorofenyl) -1- (3, 4, 5-trichlorofenyl) ) methyl, group 1- (2, 3, 4, 5, 6-pentaf luorofenyl) -1- (2, 4, 6-trimethylphenyl) methyl, group 1- (4-n-butylphenyl) -1- (2, 4 dimethylphenyl) methyl, group 1- (3,5-ditrifluoromethylphenyl) -1- (4-n-butoxifenyl) methyl, group 1- (2,4-dimethoxyphenyl) -1- (2, 3) dimethoxy-enyl) methyl, 1- (2,4,6-trimethoxy-enyl) -1- (3,5-ditrif luoromethoxy-enyl) -methyl group, 1- (3-chloro-4-methoxyphenyl) -1- (2 -chloro-4-trif luoromethoxy-enyl) methyl, 1- (3-methyl-4-f-lorofenyl) -1- (4-bromo-3-trifluoromethylphenyl) methyl group, 1- (2-methylphenyl) -l group - (3-methyl-phenyl) methyl, 1- (2-pentafluoroethylphenyl) -l- (3-pentaf-luoroethyl-phenyl) -methyl group, 1- (2-isopropyl-phenyl) -1- (2-tert-butyl-phenyl) -methyl group, Group l- (2-sec-butyl-enyl) -1- (2-n-heptaf luoropropyl-enyl) -methyl, 1- (4-n-pentylphenyl) -1- (4-n-hexylphenyl) methyl, group 1 - (2-methoxyphenyl) -1- (2,6-dimethoxyphenyl) methyl, 1- (2-pentaf luoro-ethoxy-enyl) -1- (isopropoxy-enyl) methyl group, 1- (2-tert-butoxy-enyl) group -1- ( 2-sec-butoxifenyl) methyl, group 1- (2-n-heptaf luoropropoxyphenyl) -1- (4-n-pentoxifenyl) methyl, group 1, 1-di (4-n-hexyloxy-enyl) methyl or Similar.

A C2-C6 alkenyl group phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a substituted Cl-Cß alkoxy group or not substituted by halogen can be substituted] is a group composed of 1 or 2 phenyl groups substituted by 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ halogen alkyl and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen and an alkenyl group containing 2 to 6 carbon atoms and 1 Up to 3 double links. The C2-C6 alkenyl group phenyl includes both trans and cis forms. Such a C2-C6 alkenyl phenyl group includes a 3- (2-fluorophenyl) -2-propenyl group, 3,3-di (2-fluorophenyl) -2-propenyl group, 3- (3-fluorophenyl) -2-propenyl group , 3- (4-fluorophenyl) -2-propenyl group, 3- (2,3-difluorophenyl) -2-propenyl group, 3- (2, 3, 4, 5, 6-pentafluorophenyl) -2-propenyl group, 3- (2, 4-difluorophenyl) -2-propenyl group, 3- (3,4-difluorophenyl) -2-propenyl group, 3- (3,5-difluorophenyl) -2-propenyl group, 3- (2-group -chlorophenyl) -2-propenyl, 3- (3-chlorophenyl) -2-propenyl group, 3- (4-chlorophenyl) -2-propenyl group, 3- (2,3-dichlorophenyl) -2-propenyl group 3- (2,4-dichlorophenyl) -2-propenyl, 3- (3,4-dichlorophenyl) -2-propenyl group, 3- (3,5-dichlorophenyl) -2-propenyl group, 3- (2-) group bromophenyl) -2-propenyl, 3- (3-bromophenyl) -2-propenyl group, 3- (4-bromophenyl) -2-propenyl group, 3- (2-methylphenyl) -2-propenyl group, 3- ( 3-methylphenyl) -2- propenyl, 3- (4-methylphenyl) -2-propenyl group, 3- (2-trifluoromethylphenyl) -2-propenyl group, 3- (2-fluoro-4-bromophenyl) -2-propenyl, 3- (4-chloro-3-fluorophenyl) -2-propenyl group, 3- (2, 3, 4-trichlorophenyl) -2-propenyl group , 3- (2, 4,6-trichlorophenyl) -2-propenyl group, 3- (4-isopropylphenyl) -2-propenyl group, 3- (4-n-butylphenyl) -2-propenyl group 3- ( 2,4-dimethylphenyl) -2-propenyl, 3- (2,3-dimethylphenyl) -2-propenyl group, 3- (2,6-dimethylphenyl) -2-propenyl group, 3- (3,5-dimethylphenyl) group ) -2-propenyl, 3- (2,5-dimethylphenyl) -2-propenyl group, 3- (2,4,6-trimethylphenyl) -2-propenyl group, 3- (3,5-ditrifluoromethylphenyl) -2 group -propenyl, 3- (4-n-butoxyphenyl) -2-propenyl group, 3- (2,4-dimethoxyphenyl) -2-propenyl group, 3- (2,3-dimethoxyphenyl) -2-propenyl group 3 - (2,6-dimethoxyphenyl) -2-propenyl, 3- (3,5-dimethoxyphenyl) -2-propenyl group, 3- (2,5-dimethoxyphenyl) -2-propenyl group 3- (3, 5) -ditrifluoromethoxyphenyl) -2-propenyl, 3- (3-chloro-4-methoxyphenyl-2-propenyl group, 3- (2-chloro-4-trifluoromethoxy-phenyl-2-propenyl group 3- ( 3-methyl-4-fluorophenyl) -2-propenyl, 3- (4-bromo-3-trifluoromethylphenyl) -2-propenyl group, 3- (3-trifluoromethylphenyl) -2-propenyl group, 3- (4-trifluoromethylphenyl) group ) -2-propenyl, 3- (2-trifluoromethoxy-phenyl) -2-propenyl group, 3- (3-trifluoromethoxyphenyl) -2-propenyl group, 3- (4-trifluoromethoxyphenyl) -2-propenyl group, 3- (2-group) -methoxyphenyl) -2-propenyl, 3- (3-methoxyphenyl) -2-propenyl group, 3- (4-methoxyphenyl) -2-propenyl group, 3- (3,4-dimethoxyphenyl) -2-propenyl group 3- (3, 5-dimethoxyphenyl) -2-propenyl, 4- (4-chlorophenyl) -2-butenyl group, 4- (4-chlorophenyl) -3-butenyl group, 5- (4-chlorophenyl) -2 group -pentenyl, 5- (4-chlorophenyl) -4-pentenyl group, 5- (4-chlorophenyl) -3-pentenyl group, 6- (4-chlorophenyl) -5-hexenyl group, 6- (4-chlorophenyl) group) -4-hexenyl, 6- (4-chlorophenyl) -3-hexenyl group, 6- (4-chlorophenyl) -3-hexenyl group or the like. An imidazolyl group [wherein, on the imidazole ring, at least one phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group) with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes an imidazolyl group [wherein, on the imidazole ring, 1 to 3 phenyl groups (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can to be replaced], for example, a (1-, 2-, 4 or 5-) imidazolyl group, l-phenyl-2-imidazolyl group, 2- (2-fluorophenyl) -1-imidazolyl group, 4- (3-fluorophenyl) group -2-imidazolyl, 5- (4-fluorophenyl) -3-imidazolyl group, 1- (2-chlorophenyl) -3-imidazolyl group, 2- (3-chlorophenyl) -5-imidazolyl group, group 1- (4- chlorophenyl) -2-imidazolyl, 4- (2-bromophenyl) -5-imidazolyl group, 5- (3-bromophenyl) -2-imidazolyl group, 1- (4-bromophenyl) -3-imidazolyl group, 2- (group 2-iodophenyl) -r-imidazolyl, 4- (3-iodophenyl) -5-imidazolyl group, 5- (4-iodophenyl) -1-imidazolyl group, 1- (2,3-difluorophenyl) -2-imidazolyl group, L- (3,4-difluorophenyl) -2-imidazolyl group, 1- (3,5-difluorophenyl) -2-imidazolyl group, 1- (2,4-difluorophenyl) -4-imidazolyl group, group 1- (2,6-difluorophenyl) -5-imidazolyl, l- (2,3-dichlorophenyl) -2-imidazolyl group, 1- (3,4-dichlorophenyl) -4-imidazolyl group, group 1- (3, 5-dichlorophenyl) -5-imidazolyl, 1- (2,4-dichlorophenyl) -2-imidazolyl group, l- (2,6-dichlorophenyl) -4-imidazolyl group, 1- (3, 4, 5-trifluorophenyl) group ) -5-imidazolyl, 1- (3, 4, 5-trichlorophenyl) -2-imidazolyl group, 1- (2,4,6-trifluorophenyl) -4-imidazolyl group, group 1- (2,4,6- trichlorophenyl) -5-imidazolyl, 1- (2-fluoro-4-bromophenyl) -2-imidazolyl group, 1- (4-chloro-3-fluorophenyl) -4-imidazolyl group, group 1- (2, 3, 4 -trichlorophenyl) -5-imidazolyl, 1- (2, 3, 4, 5, 6-pentafluorophenyl) -2-imidazolyl group, 1- (2,4,6-trimethylphenyl) -2-imidazolyl group, 2- (group 4-n-butylphenyl) -4-imidazolyl, 4- (2,4-dimethylphenyl) -1- imidazolyl group, 5- (2,3-dimethylphenyl) -2-imidazolyl group, 1- (2,6-dimethylphenyl) group ) -4-imidazolyl, 2- (3,5-dimethylphenyl) -5-imidazolyl group, 4- (2,5-dimethylphenyl) -1- imidazolyl group, 5- (3, 5-di-tr ifluoromethylphenyl) -2-imidazolyl, 1- (4-n-butoxyphenyl) -2-imidazolyl group, 1- (2,4-dimethoxyphenyl) -2-imidazolyl group, l- (2,3-dimethoxyphenyl) -2- group imidazolyl, 1- (2,6-dimethoxyphenyl) -2-imidazolyl group, 2- (3,5-dimethoxyphenyl) -4-imidazolyl group, 4- (2,5-dimethoxyphenyl) -1-imidazolyl group, group 5- (2,4,6-triethoxyphenyl) -2-imidazolyl, group 1- (3,5-ditrifluoromethoxy-phenyl) -2-imidazolyl, 1- (3-chloro-4-methoxyphenyl) -2-imidazolyl group, group 1- ( 2-Chloro-4-trifluoromethoxyphenyl) -2-imidazolyl, 1- (4-bromo-3-trifluoromethylphenyl) -2-imidazolyl group, 1- (2-methylphenyl) -2-imidazolyl group, 2- (3-methylphenyl) group ) -4-imidazolyl, 4- (4-methylphenyl) -5-imidazolyl group, 5- (2-methyl-3-chlorophenyl) -1-imidazolyl group, 1- (3-methyl-4-chlorophenyl) -2 group -imidazolyl, 2- (2-chloro-4-methylphenyl) -4-imidazolyl group, 4- (2-methyl-3-fluorophenyl) -5-imidazolyl group, 5- (2-trifluoromethylphenyl) -1-imidazolyl group, l- (3-trifluoromethylphenyl) -2-imidazolyl group, 2- (4-trifluorom) group ethylphenyl) -4-imidazolyl, 4- (2-pentafluoroethylphenyl) -5-imidazolyl group, 5- (3-pentafluoroethylphenyl) -1-imidazolyl group, l- (4- pentafluoroethylphenyl) -2-imidazolyl group 2- ( 2- isopropylphenyl) -4-imidazolyl, 4- (3-isopropylphenyl) -5-imidazolyl group, 5- (4-isopropylphenyl) -1-imidazolyl group, 1- (2-tert-butylphenyl) -2-imidazolyl group, 2- (3-tert-butylphenyl) -4-imidazolyl group, 4- (4-tert-butylphenyl) -5-imidazolyl group, 5- (2-sec-butylphenyl) -1-imidazolyl group, group 1- (3 -sec-butylphenyl) -2-imidazolyl, 2- (4-sec-butylphenyl) -4-imidazolyl group, 4- (2-n-heptafluoropropylphenyl) -5-imidazolyl group, 5- (3-n-heptafluoropropylphenyl) group) -1-imidazolyl, group 1- (4-n-heptafluoropropylphenyl) -2-imidazolyl, 2- (4-pentylphenyl) -4-imidazolyl group, 4- (4-hexylphenyl) -5-imidazolyl group, group 1- ( 2-methoxyphenyl) -2-imidazolyl, 5- (3-methoxyphenyl) -1-imidazolyl group, 1- (4-methoxyphenyl) -2-imidazolyl group, 2- (3-chloro-2-methoxyphenyl) -4- group imidazolyl, group 4- (2-fl) uoro-3-methoxyphenyl) -5-imidazolyl, 5- (2-fluoro-4-methoxyphenyl) -1-imidazolyl group, l- (2,6-dimethoxyphenyl) -2-imidazolyl group, group 1- (2, 3 , 4-trifluorophenyl) -2-imidazolyl, 1- (2-trifluoromethoxyphenyl) -2-imidazolyl group, 2- (3-trifluoromethoxyphenyl) -4-imidazolyl group, l- (4-trifluoromethoxyphenyl) -2-imidazolyl group l- (3-Fluoro-2-trifluoromethoxyphenyl) -2-imidazolyl, l- (2-fluoro-3-trifluoromethoxyphenyl) -2-imidazolyl group, l- (3-fluoro-4-trifluoromethoxyphenyl) -2-imidazolyl group, Group l- (3-chloro-2-trifluoromethoxyphenyl) -2-imidazolyl, 1- (2-chloro-3-trifluoromethoxyphenyl) -2-imidazolyl group, 1- (3-chloro-4-trifluoromethoxyphenyl) -2-imidazolyl group , l- (2-pentafluoroethoxyphenyl) -2-imidazolyl group, l- (3-pentafluoroethoxyphenyl) -2-imidazolyl group, l- (4-pentafluoroethoxyphenyl) -2-imidazolyl group, 1- (3-chloro-2-group pentafluoroethoxyphenyl) -2-imidazolyl, 1- (2-chloro-3-pentafluoroethoxyphenyl) -2-imidazolyl group, 1- (3-chloro-4-pentafluoroethoxyphenyl) -2-imidazole group ilo, l- (2-isopropoxyphenyl) -2-imidazolyl group, 1- (3-isopropoxyphenyl) -2-imidazolyl group, 1- (4-isopropoxyphenyl) -2-imidazolyl group, 1- (2-tert-butoxyphenyl) group -2-imidazolyl, l- (3-tert-butoxyphenyl) -2-imidazolyl group, 1- (4-tert-butoxyphenyl) -2-imidazolyl group, 1- (2-sec-butoxyphenyl) -2-imidazolyl group, 1- (3-sec-butoxyphenyl) -2-imidazolyl group, l- (4-sec-butoxyphenyl) -2-imidazolyl group, l- (2-n-heptafluoropropoxyphenyl) -2-imidazolyl group, group I- (3 -n-heptafluoropropoxyphenyl) -2-imidazolyl, group 1- (4-n-heptafluoropropoxyphenyl) -2-imidazolyl, group 1- (4-n-pentoxyphenyl) -2-imidazolyl, group 1- (4-n-hexyloxyphenyl) -2-imidazolyl, group 1, 4-diphenyl-2-imidazolyl, 1,4,5-triphenyl-2-imidazolyl group or the like. A piperadinyl group (wherein, in the piperadine ring, at least one selected from the group consisting of a C1-C6 alkyl group substituted by 2 phenyl groups [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], a Cl-Cβ alkyl phenyl group [wherein, in the phenyl ring , at least one phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen and a substituted C1-Cβ alkoxy group or not substituted by halogen can be substituted) can be substituted], a thiazolyl group (wherein, in the thiazole ring, at least one phenyl group can be substituted), a Cl-Cβ phenoxy alkyl group (wherein, on the phenyl ring , at least one selects of the group consisting of a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen and an alkoxy group Cl- Cβ substituted or unsubstituted with halogen can be substituted), a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen can be substituted), an alkenyl group C2-C6 phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a substituted or unsubstituted C1-C6 alkoxy group with halogen can be substituted] and an imidazolyl group [wherein, on the imidazole ring, at least one phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl groupCl-Cβ substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] is substituted) includes a piperadinyl group (wherein, in the piperadine ring, 1 to 3 substituents selected from the group consisting of a Cl-Cß alkyl group substituted by 2 phenyl groups as described above [wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted by halogen and a Cl-Cβ alkoxy group substituted or unsubstituted by halogen can be substituted], a Cl-Cß alkyl phenyl group [wherein, on the phenyl ring, 1 to 3 groups phenoxy (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with loogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) are substituted], a thiazolyl group as described later (wherein, in the thiazole ring, 1 or 2 phenyl groups can be substituted), a Cl-Cβ phenoxy alkyl group as described later (where, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a phenyl group as described above (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consists of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a halogen atom, a substituted Cl-Cβ alkyl group or not substituted by halogen and a Cl-Cβ alkoxy group substituted or unsubstituted by halogen can be substituted), a C2-C6 alkenyl group phenyl [a group composed of 1 or 2 phenyl groups substituted by 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a C1-Cβ alkoxy group substituted or unsubstituted with halogen and a alkenyl group containing 2 to 6 carbon atoms and having 1 to 3 double bonds] and an imidazolyl group [wherein, on the imidazole ring, 1 to 3 phenyl groups (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] are substituted), for example, 4- (1,1-di (4-chlorophenyl) methyl] -1-piperadinyl group, 4- (1,1-di (4-trifluoromethoxyphenyl) methyl) -1-piperadinyl group, group 4 - (4-chlorocinnamyl) -1-piperadinyl, 4- (4-trifluoromethoxycinnamyl) -1-piperadinyl group, 4- (l- (4-chlorophenyl) -2-imidazolyl] -1-piperadinyl group, group 4- (1 , 1-di (2,4-dibromophenyl) methyl] -1-piperadinyl, 4- (1,1-di (4-trifluoromethylphenyl) methyl] -1-piperadinyl group, 4- (2, 4-dichlorocinnamyl) group ) -1-piperadinil , 4- (4-trifluoromethylcinnamyl) -1-piperadinyl group, 4- (l- (2,4-di (trifluoromethoxy) phenyl] -2-imidazolyl) -1-piperadinyl group, 4- (1,1-di) group (2,4,6-trifluorophenyl) methyl] -1-piperadinyl, 4- (1,1-di (2,4-di (trifluoromethoxy) phenyl] methyl) -1-piperadinyl group 4- (2, 4) , 6-tri (trifluoromethoxy) cinnamyl] -1-piperadinyl, 4- (2,4-di (trifluoromethoxy) -cinnamyl] -1-piperadinyl group, 4- (1- (4-trifluoromethylphenyl) -2-imidazolyl group] -1-piperadinyl, 4- (2,4,6-trifluoro-cinnamyl) -1-piperadinyl group, 4- (1- (2,4-dibromophenyl) -2-imidazolyl] -l-piperadinyl group, group 4- (1 , 1-di (4-chlorophenyl) methyl] -3- (4-chlorocinnamyl) -1-1-piperadinyl, 4- (4-trifluoromethoxycinnamyl) -2- (1- (4-chlorophenyl) -2-imidazolyl group] -1-piperadinyl, 4- (4-trifluoromethoxycinnamyl) -2- (1- (4-chlorophenyl) -2-imidazolyl] -6- (1-imidazolyl) -1-piperadinyl group, 4- (4- (4 -trifluoromethoxyphenoxy) benzyl] - (1-, 2- or 3-) piperadynyl, 4- (4-phenyl- (2- or 5-) thiazolyl] - (1-, 2) group - or 3-) piperadinil, group 4- (2- (4-trifluoromethoxy-enoxy) ethyl] - (1-, 2- or 3-) piperadinyl, group 4- (2- (4-f-enylf-enoxy) ethyl] - (1-, 2- or 3-) piperadinyl, 4- (2- (4-chlorophenoxy) ethyl] - (l-, 2- or 3-) piperadinyl group 4- (2- (3, 4- dichlorophenoxy) ethyl] - (1-, 2- or 3-) piperadinyl, 4- (2- (4-trifluoromethyl-enoxy) -ethyl] - (1-, 2- or 3-) piperadinyl group 4- ( 2- (4-trifluoromethoxyphenoxy) ethyl] - (1-, 2- or 3-) piperadynyl or the like. An anilino C1-C6 alkyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C3 alkyl group substituted or unsubstituted with halogen and a substituted C1-Cβ alkoxy group or unsubstituted with halogen can be substituted] includes a group composed of an anilino group which can be substituted by a Cl-Cß alkyl group at the N-position of the anilino group and is unsubstituted or substituted by 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a Cl-Cß alkyl group substituted or unsubstituted with halogen as defined above, a Cl-Cβ alkoxy group substituted or unsubstituted with halogen and a halogen, and a Cl-Cß alkyl group, examples of which include an anilinomethyl group, N-methyl-N-anilinomethyl group, N-ethyl-N- group anilinomethyl, Nn-propyl-N-anilinomethyl group, N-butyl-N-anilinomethyl group, Nn-pentyl-N-anilinomethyl group, N-hexyl-N-anilinomethyl group, 2-anilinoethyl group, 3-anilinopropyl group, group 4 -anilinobutyl, 5-anilinopentyl group, 6-anilinohexyl group, 4-fluoroanilinomethyl group, 2-fluoro-4-bromoanilinomethyl group, 4-chloro-3-fluoroanilinomethyl group, 2,3,4-trichloroanilinomethyl group, group 3,4, 5-trichloroanilinomethyl, 2,4-trichloroanilinomethyl group, N-methyl-N-2,4,6-trichloroanilinomethyl group, 4-isopropylanilinomethyl group, 4-n-butylanilinomethyl group, 4-methylanilinomethyl group, 2-methylanilinomethyl group, 3-methylanilinomethyl group, 2,4-dimethylanilinomethyl group, 2,3-dimethylanilinomethyl group, 2,6-dimethylanilinomethyl group, 3,5-dimethylane group linomethyl, 2,5-dimethylanilinomethyl group, N-methyl-N-2,5-dimethoxyanilinomethyl group, 2,4-, 3-trimethylanilinomethyl group, 3,5-ditrifluoromethylanilinomethyl group, 2,3,4,5-b-pentafluoroanilinomethyl group , 4-isopropoxyanilinomethyl group, 4-n-butoxyanilinomethyl group, 4-methoxyanilinomethyl group, 2-methoxyanilinomethyl group, 3-methoxyanilinomethyl group, N-methyl-N-3-methoxyanilinomethyl group, 2,4-dimethoxyanilinomethyl group, group 2,3 - dimethoxyanilinomethyl, 2,6-dimethoxyanilinomethyl group, 3,5-dimethoxyanilinomethyl group, 2,5-dimethoxyanilinomethyl group, 2,4,6-trimethoxyanilinomethyl group, 3,5-ditrifluoromethoxyanilinomethyl group, 2-isopropoxyanilinomethyl group, 3-chloro group 4-methoxyanilinomethyl, 2-chloro-4-trifluoromethoxyanilinomethyl group, 3-methyl-4-fluoroanilinomethyl group, 4-bromo-3-trifluoromethylanilinomethyl group, 2- (4-fluoroanilino) ethyl group, 3- (4-fluoroanilino) propyl group , 4- (4-fluoroanilino) butyl group, 5- (4-fluoroanilino) pentyl group, 6- (4-fluoroan) group ilino) hexyl, 4-chloroanilinomethyl group, 2- (4-chloroanilino) ethyl group, 3- (4-chloroanilino) propyl group, 4- (4-chloroanilino) butyl group, 5- (4-chloroanilino) pentyl group 6- (4-chloroanilino) hexyl, 4-methylanilinomethyl group, 2- (4-methylanilino) ethyl group, 3- (4-methylanilino) propyl group, 4- (4-methylanilino) butyl group, 5- (4-) group methylanilino) pentyl, 6- (4-methylanilino) hexyl group, 4-trifluoromethylanilinomethyl group, 2- (4-trifluoromethylanilino) ethyl group, 3- (4-trifluoromethylanilino) propyl group, 4- (4-trif) group luoromethylanilino) butyl, N-methyl-N- (4- (4-trifluoromethylanilino)] butyl group, 5- (4-trifluoromethylanilino) pentyl group, β- (4-trifluoromethylanilino) hexyl group, 4-trifluoromethoxyanilinomethyl group, N-methyl-N-4-trifluoromethoxyanilinomethyl group, 2- (4-trifluoromethyl methoxyanilino) ethyl group, 3- (4-trifluorophoxyanilino) propyl group, 4- (4-trifluoromethoxyanilino) butyl group, 5- (4-trif luoromethoxyanilino) group ) pentyl, 6- (4-trifluoromethoxyanilino) hexyl group, 4-methoxyanilinomethyl group, 2- (4-methoxyanilino) ethyl group, 3- (4-methoxyanilino) propyl group, 4- (4-methoxyanilino) butyl group 5 - (4-methoxyanilino) pentyl, ß- (4-methoxyanilino) hexyl group. An alkoxy Cl-Cβ thiazolyl group (wherein, in the thiazole ring, at least one selected from the group consisting of a Cl-Cß (p-1) phenoxy alkyl group [wherein, in the phenyl ring, at least one selected of the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted or unsubstituted Cl-Cβ alkoxy group with halogen can be substituted], a C1-C6 alkyl group (p-2) ) anilino [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted], an alkyl Cl-Cß (p-3) phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], a Cl-Cβ alkyl group (p-4) piperadinyl group [wherein, in the piperadine ring, at least one phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen can be substituted) can be substituted] and a C 1 -C 6 alkyl group (p-5) piperidyl [wherein, in the piperidine ring, at least one phenoxy group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted Cl-Cβ alkyl group) or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] can be substituted) includes a Cl-Cβ thiazolyl alkoxy group (wherein, in the thiazole ring, 1 to 3 substituents selected from the group consisting of a C 1 -C 6 alkyl phenoxy group as described later [wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a group C 1 -C 6 alkyl substituted or unsubstituted by halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted by halogen can be substituted], an anilino C 1 -C 6 alkyl group as described above [wherein, on the phenyl ring, 1 to 5, prefe 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted by halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], an alkyl Cl group -Cβ phenyl as described above [wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen can be substituted], a C 1 -C 6 alkyl piperadynyl group as described above [wherein, in the piperadine ring, 1 to 3 phenyl groups (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a substituted C1-C6 alkoxy group or unsubstituted with halogen can be substituted) can be substituted] and a C1-C6 alkyl piperidyl group as described above [wherein, in the piperidine ring, 1 to 3 phenoxy groups (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted ] can be substituted), for example, a (2-thiazolyl) methoxy group, 2- (4-thiazolyl) ethoxy group, 3- (5-thiazolyl) propoxy group, 4- (2-thiazolyl) butoxy group, group 5 - (4-thiazolyl) pentyloxy, 6- (5-thiazolyl) hexyloxy group, group (4- (4- (4-chlorophenoxy) -1-piperidylmethyl] -2-thiazolyl) methoxy, group (4- (4- ( 4-trifluoromethylphenoxy) -1-piperidylmethyl] -2-thiazolyl) methoxy, 2-methyl-3- (2-thiazolyl) propoxy group, 1-l-dimethyl-2- (2-thiazolyl) ethoxy group (4 - (4- (4-trifluoromethoxyphenoxy) -1-piperidylmethyl] -2-thiazolyl) methoxy, group (4- (4- (2,4-di (trifluoromethoxy) phenoxy] -1-piperidylmethyl) -2-thiazolyl] methoxy , group (4- (4- (2,4,6-Trifluoromethyl) phenoxy] -1-piperidylmethyl) -2-thiazolyl] methoxy, group (4- (4- (2,4-dibromophenoxy) -1- piperidylmethyl] -2-thiazolyl) methoxy, group (4- (4- (2,4,6-trifluorophenoxy) -1-piperidylmethyl] -2-thiazolyl) methoxy, group (4- (4- (2, -dibromophenoxy)) -1-piperidylmethyl] -2-thiazolyl) methoxy, group (4- (4- (4-trifluoromethoxyphenyl) -1-piperadinylmethyl] -2-thiazolyl) methoxy, group (4- (4- (4-chlorophenyl)) -1-piperadinylmethyl] -2-thiazolyl) methoxy, group (4- (4- (2,4-di (trifluoromethyl) phenyl] -1-piperadinylmethyl) -2-thiazolyl] methoxy, group (4- (4- ( 2,4,6-Tri- (trifluoromethoxy) phenyl] -1-piperadinylmethyl) -2-thiazolyl] methoxy group (4- (4- (2,4-dibromofenyl) -1-piperadinylmethyl] -2-thiazolyl) methoxy group (4- (4- (2, 4, 6-trif luorofenyl) -l-piperadinylmethyl] -2-thiazolyl) methoxy, group 4- (4-trifluoromethyl-phenoxymethyl) -2-thiazolyl, group (4- (4 -trifluoromethoxy-phenoxymethoxy) -2-thiazolyl] methoxy, group (4- (4-chlorofenoxymethyl) -2-thiazolyl] methoxy, group (4- (2,4-di (trifluoromethoxy) phenoxymethyl] -2-thiazolyl) methoxy, group (4- (2,4,6-tri (trifluoromethyl) phenoxymethyl] -2-thiazolyl) methoxy group (4- (2,4-dibromophenoxymethyl) -2-thiazolyl] methoxy group (4- (2,4, 6-trif luorofenoxymethyl) -2-thiazolyl] methoxy, group (4- (4-trifluoromethylanilinomethyl) -2-thiazolyl] methoxy, group (4- (4-trifluoromethoxyanilinomethoxy) -2-thiazolyl] methoxy, group (4- (4-chloroanilinomethyl) -2-thiazolyl] methoxy, group (4- (2,4-di (trifluoromethoxy) anilinomethyl] -2-thiazolyl) methoxy, group (4- (2,4,6-tri (trifluoromethyl) anilinomethyl) ] -2-thiazolyl) methoxy, group (4- (2,4-dibromoanilinomethyl) -2-thiazolyl] methoxy, group (4- (2,4,6-trifluoroanilinomethyl) -2-thiazolyl] methoxy, group (4) - (3- (4-trifluoromethoxyphenyl) propi l] -2-thiazolyl) methoxy, group (4- (3- (4-trifluoromethylphenyl) propyl] -2-thiazolyl) methoxy, group (4- (3- (4-chlorofenyl) propyl] -2-thiazolyl) methoxy, group (4- (2, 4-diiodobenzyl) -2-thiazolyl] methoxy, group (4- (2, 4, 6-tribromobenzyl) -2-thiazolyl] methoxy, group (4- (2,4-di (trifluoromethoxy) benzyl] -2-thiazolyl ) methoxy, group (4- (2,4,6-tri (trifluoromethyl) benzyl] -2-thiazolyl) methoxy group (4,5-dibenzyl-2-thiazolyl) methoxy, (2-phenoxymethyl-4-benzyl-5-thiazolyl) methoxy group, (2,5-dianilinomethyl-4-thiazolyl) methoxy group or the like. An 8-azabicyclo [3.2.1] octyl group (wherein, in the 8-azabicyclo [3.2.1] octane ring, at least one phenoxy group [wherein, in the phenyl ring, at least one selected from the group consisting of of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted) includes an 8-azabicyclo group [3.2.1] octyl (wherein, in the 8-azabicyclo [3.2.1] octane ring, 1 to 3 phenoxy groups as described above [wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted), for example, an 8-azabicyclo group [3.2 .1] octyl, 3- (4-trifluoromethoxyphenoxy) -8-azabicyclo [3.2.1] octyl group or, 3- (4-trifluoromethylphenoxy) -8-azabicyclo [3.2.1] octyl group, 3- (4-chlorophenoxy) -8-azabicyclo [3.2.1] octyl group, 3- (2,4-dichlorophenoxy) group -8-azabicyclo [3.2.1] octyl, 3- (2,4,6-trichlorophenoxy) -8-azabicyclo [3.2.1] octyl group, 3- (2-bromophenoxy) -8-azabicyclo group [3.2.1 ] octyl, 3- (3-fluorophenoxy) -8-azabicyclo [3.2.1] octyl group, 3- (2,4-di (trifluoromethoxy) phenoxy] -8-azabicyclo [3.2.1] octyl group, group 3 (2, 4,6-Tri- (trifluoromethoxy) phenoxy] -8-azabicyclo [3.2.1] octyl, 3- (2,4-di (trifluoromethyl) phenoxy] -8-azabicyclo [3.2.1] octyl group 3- (2,4,6-Trifluoromethyl) phenoxy] -8-azabicyclo [3.2.1] octyl group 3,6-diphenoxy-8-azabicyclo [3.2.1] octyl group 3,7,6- triphenoxy-8-azabicyclo [3.2.1] octyl, 3- (4-methoxyphenoxy) -8-azabicyclo [3.2.1] octyl group, 3- (4-methylphenoxy) -8-azabicyclo [3.2.1] octyl group, 3- (2, 4-dimethoxyphenoxy) -8-azabicyclo [3.2.1] octyl group, 3- (2,4,6-trimethoxyphenoxy) -8-azabicyclo [3.2.1] octyl group, group 3- (2,4-dimethylphenoxy) -8-azabicyclo [3.2.1] octyl, 3- (2,4,6-trimethylphenoxy) -8-azabicyclo [3.2.1] octyl group or the like. An amino-substituted Cl-Cß alkyl group which may have a Cl-Cß alkyl group as a substituent includes a Cl-Cß amino alkyl group which may have 1 or 2 Cl-Cß alkyl groups as a substituent, for example, a aminomethyl group, 2-aminoethyl group, 1-aminoethyl group, 3-aminopropyl group, 4-aminobutyl group, 5-aminopentyl group, 6-aminohexyl group, 2-methyl-3-aminopropyl group, 1-l-dimethyl-2-aminoethyl group, ethylaminomethyl group, 1- (propylamino) ethyl group, 2- (methylamino) ethyl group, 3- (isopropylamino group ) propyl, 4- (n-butylamino) butyl group, 5- (n-pentylamino) pentyl group, 6- (n-hexylamino) hexyl group, dimethylaminomethyl group, (N-ethyl-N-propylamino) methyl group, group 2 - (N-methyl-N-hexylamino) ethyl or the like. A Cl-Cβ alkylene group includes a methylene group, ethylene group, trimethylene group, 2-methyltrimethylene group, 2-dimethyltrimethylene group, 1-methyltrimethylene group, methylmethylene group, ethylmethylene group, tetramethylene group, pentamethylene group, hexamethylene group or the like . A C 1 -C 6 alkoxycarbonyl phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen can be substituted] includes a group composed of an alkoxy group Cl-Cβ phenyl which can be substituted by 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, an alkyl group Cl-Cβ substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen as defined above and a carbonyl group, examples of which include a benzyloxycarbonyl group, 2-phenylethoxycarbonyl group, 3-phenylpropoxycarbonyl group, 2- f-enylpropoxycarbonyl group, 4-phenylbutoxycarbonyl group, 5- phenylpentoxycarbonyl group, 4-phenylpentoxycarbonyl group, 6-phenylhexyloxycarbonyl group, 2-f luorobenzyloxycarbonyl group, 3-fluorobenzyloxycarbonyl group, 4-f luorobenzyloxycarbonyl group, 2- (group 2- fluorophenyl) ethoxycarbonyl, 2- (3-f luorofenyl) ethoxycarbonyl group, 2- (4-f luorofenyl) ethoxycarbonyl group, 2-chlorobenzyloxycarbonyl group, 3-chlorobenzyloxycarbonyl group, 4-chlorobenzyloxycarbonyl group, group 2-f luoro-4-bromobenzyloxycarbonyl, group 4-chloro-3-f luorobenzyloxycarbonyl, group 2, 3, 4-trichlorobenzyloxycarbonyl, group 3, 4, 5-trif luorobenzyloxycarbonyl, group 2, 3, 4, 5, 6-pentaf luorobenzyloxycar bonyl, group 2, 4, ß-trichlorobenzyloxycarbonyl, 4-isopropylbenzyloxycarbonyl group, 4-n-butylbenzyloxycarbonyl group, 4-methylbenzyloxycarbonyl group, 2-methylbenzyloxycarbonyl group, 3-methylbenzyloxycarbonyl group, 2, 4-dimethylbenzyloxycarbonyl group, group 2, 3-Dimethylbenzyloxycarbonyl, Group 2, 6-dimethylbenzyloxycarbonyl, Group 3, 5-dimethylbenzyloxycarbonyl, Group 2, 5-dimethyl-isobenzyloxycarbonyl, Group 2, 4, 6-trimethyl-isobenzyloxycarbonyl, Group 3, 5-dimitrifluoromethylbenzyloxycarbonyl, 4-isopropoxybenzyloxycarbonyl group, group 4-n-butoxybenzyloxycarbonyl, 4-methoxybenzyloxycarbonyl group, 2-methoxybenzyloxycarbonyl group, 3-methoxybenzyloxycarbonyl group, 2,4-dimethoxybenzyloxycarbonyl group, 2,3-dimethoxybenzyloxycarbonyl group, 2,6-dimethoxybenzyloxycarbonyl group, 3, 5-dimethoxybenzyloxycarbonyl group, group 2, 5-dimethoxybenzyloxycarbonyl, group 2, 4,6-trimethoxybenzyloxycarbonyl, 3,5-ditrifluoromethoxybenzyloxycarbonyl group, 2-isopropoxybenzyl group xicarbonyl, 3-chloro-4-methoxybenzyloxycarbonyl group, 2-chloro-4-trifluoromethoxybenzyloxycarbonyl group, 3-methyl-4-f luorobenzyloxycarbonyl group, 4-bromo-3-trifluoromethylbenzyloxycarbonyl group, 2- (2-chlorophenyl) ethoxycarbonyl group 2- (3-chlorofenyl) ethoxycarbonyl, 2- (4-chlorophenyl) ethoxycarbonyl group, 2-trifluoromethylbenzyloxycarbonyl group, 3-trifluoromethylbenzyloxycarbonyl group, 4-trifluoromethylbenzyloxycarbonyl group, 2-trifluoromethoxybenzyloxycarbonyl group, 3-trifluoromethoxybenzyloxycarbonyl group, 4-trifluoromethoxybenzyloxycarbonyl group, 2- (2-trif luoromethylphenyl) ethoxycarbonyl group, 2- (3-trif luoromethylphenyl) ethoxycarbonyl group, 2- (4-trif luoromethylphenyl) ethoxycarbonyl group, 2- (2-trif luoromethoxy) group enyl) ethoxycarbonyl, 2- (3-trifluoromethoxyphenyl) ethoxycarbonyl group, 2- (4-trifluoromethoxyphenyl) ethoxycarbonyl group, 3- (2-trifluoromethylphenyl) propoxycarbonyl group, 3- (3-trifluoromethylphenyl) propoxycarbonyl group , group or 3- (4-trifluoromethylphenyl) propoxycarbonyl, 3- (2-trifluoromethylphenyl) propoxycarbonyl group, 3 ~ (3-trifluoromethoxyphenyl) propoxycarbonyl group, 3- (4-trifluoromethoxyphenyl) propoxycarbonyl group 4 - (3-trifluoromethyl-phenyl) -butoxycarbonyl, 5- (4-trifluoromethyl-phenyl) -pentyloxycarbonyl group, 4- (4-trifluoromethyl-phenyl) -pentyloxycarbonyl group, 4- (4-trifluoromethoxy-phenyl) -pentyloxycarbonyl group, 6- (3-trifluoromethyl-phenyl) -hexyl-hexylcarbonyl group β- (4-trifluoromethylphenyl) hexylxylcarbonyl, 6- (4-trifluoromethoxyphenyl) hexyloxycarbonyl group or the like. A C2-C6 alkenylcarbonyl phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C1-C6 alkyl group with halogen and a substituted or unsubstituted C1-C6 alkoxy group with halogen can be substituted] includes a group consisting of a phenyl group substituted by 1 to 5, preferably 1 to 3 selected substituents of the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen and an alkenylcarbonyl group containing 2 to ß carbon atoms and having 1 to 3 double links. The C2-C6 alkenylcarbonyl group phenyl includes both trans and cis forms. Such a C2-C6 alkenylcarbonyl phenyl group includes a 2-phenylvinylcarbonyl group, 3-phenyl-2-propenylcarbonyl group (common name: cinnamoyl), 4-phenyl-2-butenylcarbonyl group, 4-phenyl-3-butenylcarbonyl group, group 4 phenyl-1,3-butadienylcarbonyl, 5-phenyl-1,3,5-hexatrienylcarbonyl group, 3- (2-fluorophenyl) -2- propenylcarbonyl group, 3- (3-fluorophenyl) -2-propenylcarbonyl group, group 3 (4-fluorophenyl) -2-propenylcarbonyl, 3- (2,3-difluorophenyl) -2-propenylcarbonyl group, 3- (2, 3, 4, 5, 6-pentafluorophenyl) -2-propenylcarbonyl group, 3- ( 2,4-difluorophenyl) -2-propenylcarbonyl, 3- (3,4-difluorophenyl) -2-propenylcarbonyl group, 3- (3,5-difluorophenyl) -2-propenylcarbonyl group, 3- (2-chlorophenyl) - group 2-propenylcarbonyl, 3- (3-chlorophenyl) -2-propenylcarbonyl group, 3- (4-chlorophenyl) -2-propenylcarbonyl group, 3- (2,3-dichlorophenyl) -2-propenylcarbonyl group, group 3- (2 , 4-dichlorophenyl) -2-propenylcarboyl, 3- (3,4-dichlorophenyl) -2-propenylcarbonyl group , 3- (3,5-dichlorophenyl) -2-propenylcarbonyl group, 3- (2-bromophenyl) -2-propenylcarbonyl group, 3- (3-bromophenyl) -2-propenylcarbonyl group, 3- (4-bromophenyl) group -2-propenylcarbonyl, 3- (2-methylphenyl) -2-propenylcarbonyl group, 3- (3-methylphenyl) -2-propenylcarbonyl group, 3- (4-methylphenyl) -2-propenylcarbonyl group, 3- (4-) group trifluoromethylphenyl) -2-propenylcarbonyl, 3- (2-fluoro-4-bromophenyl) -2-propenylcarbonyl group, 3- (4-chloro-3-fluorophenyl) -2-propenylcarbonyl group, group 3- (2,3,4 -trichlorophenyl) -2-propenylcarbonyl, 3- (2,4,6-trichlorophenyl) -2-propenylcarbonyl group, 3- (4-isopropylphenyl) -2-propenylcarbonyl group, 3- (4-n-butylphenyl) -2 group -propenylcarbonyl, 3- (2,4-dimethylphenyl) -2-propenylcarbonyl group, 3- (2,3-dimethylphenyl) -2-propenylcarbonyl group, 3- (2,6-dimethylphenyl) -2-propenylcarbonyl group, group 3 (3, 5-dimethylphenyl-2-propenylcarbonyl, 3- (2,5-dimethylphenyl) -2-propenylcarbonyl group, 3- (2,4,6-tri-ethylphenyl) -2-propenylcarbonyl group , 3- (3, 5-ditrifluoromethylphenyl) -2-propenylcarbonyl group, 3- (4-n-butoxyphenyl) -2-propenylcarbonyl group, 3- (2,4-dimethoxyphenyl) -2-propenylcarbonyl group, group 3- ( 2, 3-dimethoxyphenyl) -2-propenylcarbonyl, 3- (2, β-dimethoxyphenyl) -2-propenylcarbonyl group, 3- (3,5-dimethoxyphenyl) -2-propenylcarbonyl group, 3- (2,5-dimethoxyphenyl) group ) -2-propenylcarbonyl, 3- (3,5-ditrifluoromethoxyphenyl) -2-propenylcarbonyl group, 3- (3-chloro-4-methoxyphenyl) -2-propenylcarbonyl group, 3- (2-chloro-4-trifluoromethoxyphenyl) group -2-propenylcarbonyl, 3- (3-methyl-4-fluorophenyl) -2-propenylcarbonyl group, 3- (4-bromo-3-trifluoromethylphenyl) -2-propenylcarbonyl group, 3- (3-trifluoromethylphenyl) -2- group propenylcarbonyl, 3- (4-trifluoromethylphenyl) -2-propenylcarbonyl group, 3- (2-trifluoromethoxyphenyl) -2-propenylcarbonyl group, 3- (3-trifluoromethoxyphenyl) -2-propenylcarbonyl group, 3- (4-trifluoromethoxyphenyl) - group 2-propenylcarbonyl, 3- (2-methoxyphenyl) -2-propenylcarbonyl group, group 3- (3-methoxyphenyl) -2-propenylcarbonyl, 3- (4-methoxyphenyl) -2- propenylcarbonyl group, 3- (3,4-dimethoxyphenyl) -2-propenylcarbonyl group, 3- (3,5-dimethoxyphenyl) group -2-propenylcarbonyl, 4- (4-chlorophenyl) -2-butenylcarbonyl group, 4- (4-chlorophenyl) -3-butenylcarbonyl group, 5- (4-chlorophenyl) -2-pentenylcarbonyl group, group 5- ( 4-chlorophenyl) -4-pentenylcarbonyl, 5- (4-chlorophenyl) -3-pentenylcarbonyl group, 6- (4-chlorophenyl) -5-hexenylcarbonyl group, 6- (4-chlorophenyl) -4-hexenylcarbonyl group, 6- (4-chlorophenyl) -3 group -hexenylcarbonyl, 6- (4-chlorophenyl) -3-hexenylcarbonyl group or the like. A C1-C4 alkylenedioxy group includes a methylenedioxy group, ethylenedioxy group, trimethylenedioxy group, tetramethylenedioxy group or the like. An amino substituted sulfonyl group which may have a Cl-Cß alkyl group as a substituent includes an aminosulfonyl group which may have 1 to 2 Cl-Cß alkyl groups as a substituent, for example an aminosulfonyl group, methylaminosulfonyl group, ethylaminosulfonyl group, propylaminosulfonyl group, isopropylaminosulfonyl group, butylaminosulfonyl group, tert-butylaminosulfonyl group, pentylaminosulfonyl group, hexylaminosulfonyl group, dimethylaminosulfonyl group, diethylaminosulfonyl group, dipropylaminosulfonyl group, dibutylaminosulfonyl group, dipentylaminosulfonyl group, dihexylaminosulfonyl group, N-methyl-N-ethylaminosulfonyl group, N- group ethyl-N-propylaminosulfonyl, N-methyl-N-butylaminosulfonyl group, N-methyl-N-hexylaminosulfonyl group or the like. A C 1 -C 3 alkoxy phenyl group includes a benzyloxy group, 2-phenylethoxy group, 1-phenylethoxy group, 3-phenylpropoxy group, 2-phenylpropoxy group, 4-phenylbutoxy group, 5-phenylpentoxy group, 4-phenylpentoxy group, 6-group. phenylhexyloxy, 2-methyl-3-phenylpropoxy group, 1-l-dimethyl-2-phenylethoxy group or the like. A pyrrolidinyl group [wherein, in the pyrrolidine ring, at least one oxo group can be substituted] includes a pyrrolidinyl group (wherein, in the pyrrolidine ring, 1 or 2 oxo groups can be substituted), for example, a pyrrolidinyl group , 2-oxopyrrolidinyl group, 2, 5-dioxopyrrolidinyl group or the like. A Cl-Cβ pyrrolidinyl alkoxy group includes a (1-pyrrolidinyl) methoxy group, 2- (1-pyrrolidinyl) -ethoxy group, 1- (2-pyrrolidinyl) ethoxy group, 3- (1-pyrrolidinyl) propoxy group, group 2 - (3-pyrrolidinyl) propoxy, 4- (l-pyrrolidinyl) butoxy group, 5- (2-pyrrolidinyl) pentoxy group, 4- (3-pyrrolidinyl) pentoxy group, 6- (1-pyrrolidinyl) hexyloxy group, group 2 -methyl-3- (1-pyrrolidinyl) propoxy, group 1, l-dimethyl-2- (1-pyrrolidinyl) ethoxy or the like. A Cl-Cβ benzofuryl alkyl group (wherein, in the benzofuran ring, at least one halogen atom can be substituted as a substituent) includes a C 1 -C 6 alkyl group substituted with benzofuryl which can be substituted by 1 to 3 halogen atoms in the benzofuran ring, for example, a 2-benzofurylmethyl group, 1- (2-benzofuryl) ethyl group, 2- (4-benzofuryl) ethyl group, 3- (5- benzofuryl) propyl group, 4- (6-) group benzofuryl) butyl, 5- (7- benzofurylpentyl, 6- (2-benzofuryl) hexyl, 4- fluoro-2-benzofurylmethyl group, 5-fluoro-2-benzofurylmethyl group, 6-fluoro-2-benzofurylmethyl group, group 7-fluoro-2-benzofurylmethyl, 4-chloro-2-benzofurylmethyl group, 5-chloro-2-benzofurylmethyl group, 6-chloro-2-benzofurylmethyl group, 7-chloro-2-benzofurylmethyl group, 4-bromo-2 group -benzofurylmethyl, 5-bromo-2-benzofurylmethyl group, 6-bromo-2-benzofurylmethyl group, 7-bromo-2-benzofurylmethyl group, 4-iodo-2-benzofurylmethyl group, 5-iodo-2-benzo group furylmethyl, 6-iodo-2-benzofurylmethyl group, 7-iodo-2-benzofurylmethyl group, 4-fluoro-3-benzofurylmethyl group, 5-fluoro-3-benzofurylmethyl group, 6-fluoro-3-benzofurylmethyl group, group 7 fluoro-3-benzofurylmethyl, 4-chloro-3-benzofurylmethyl group, 5-chloro-3-benzofurylmethyl group, 6-chloro-3-benzofurylmethyl group, 7-chloro-3-benzofurylmethyl group, 4-bromo-3-benzofurylmethyl group , 5-bromo-3-benzofurylmethyl group, 6-bromo-3-benzofurylmethyl group, 7-bromo-3-benzofurylmethyl group, 4-iodo-3-benzofurylmethyl group, 5-iodo-3-benzofurylmethyl group, group 6-iodine -3-benzofurylmethyl, 7-iodo-3-benzofurylmethyl group, 2- (4-fluoro-2-benzofuryl) ethyl group, 2- (5-fluoro-2-benzofuryl) ethyl group, 2- (6-fluoro- 2-benzofuryl) ethyl, 2- (7-fluoro-2-benzofuryl) ethyl group, 2- (4-chloro-2-benzofuryl) ethyl group, 2- (5-chloro-2-benzofuryl) ethyl group, 2- (6-chloro) group -2-benzofuryl) ethyl, 2- (7-chloro-2-benzofuryl) ethyl group, 2- (4-fluoro-3-benzofuryl) methyl group, 2- (5-f luoro-3-benzofuryl) methyl group, 2- (6-fluoro-3-benzofuryl) ethyl group, 2- (7-fluoro-3-benzofuryl) ethyl group, 2- (4-chloro-3-benzofuryl) ethyl group, 2- (5-chloro- 3-benzofuryl) ethyl, 2- (6-chloro-3-benzofuryl) ethyl group, 2- (7-chloro-3-benzofuryl) ethyl group, 2- (4-fluoro-2-benzofuryl) ethyl group, group 6 - (5-fluoro-2-benzofuryl) hexyl, group 6- (6-f luoro-2-benzofuryl) hexyl, 6- (7-fluoro-2-benzofuryl) hexyl group, group 6- (4-chloro-2) -benzofuryl) hexyl, 6- (5-chloro-2-benzofuryl) hexyl group, 6- (6-chloro-2-benzofuryl) hexyl group, β- (7-chloro-2-benzofuryl) hexyl group, group β- (4-fluoro-3-benzofuryl) methyl, 6- (5-fluoro-3-benzofuryl) hexyl group, 6- (6-f luoro-3-benzofuryl) hexyl group, 6- (7-fluoro-3-) group benzofuril ) hexyl, 6- (4-chloro-3-benzofuryl) hexyl group, 6- (5-chloro-3-benzofuryl) hexyl group, 6- (6-chloro-3-benzofuryl) hexyl group, group 6- (7) -chloro-3-benzofuryl) hexyl, group (2,4-dibromo-3-benzofuryl) methyl, group (4, 5, 6-trichloro-3-benzofuryl) methyl or the like. A Cl-Cβ phenoxy alkyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a substituted C1-C6 alkoxy group or not substituted by halogen can be substituted) is a group composed of a phenoxy group unsubstituted or substituted by 1 to 5, preferably 1 to 3 substituents selected from a C1-C6 alkyl group substituted or unsubstituted with halogen, an alkoxy C1 group -C6 substituted or unsubstituted with halogen and a halogen as defined above and a Cl-Cß alkyl group, examples of which include a phenoxymethyl group, 2-phenoxyethyl group, 3-phenoxypropyl group, 4-phenoxybutyl group, group 5 phenoxypentyl, 6-phenoxyhexyl group, 4-fluoro-6-methylphenoxymethyl group, 2-fluoro-4-bromophenoxymethyl group, 2-fluoro-4-bromophenoxymethyl group, 4-chloro-3-fluorophenoxymethyl group, 2-chlorophenoxymethyl group, group 3 -chlorophenoxymethyl or, 4-chlorophenoxymethyl group, 3,4-dichlorophenoxymethyl group, 2, 3, 4-trichlorophenoxymethyl group, 3, 4, 5-trichlorophenoxymethyl group 2, 4,6-trichlorophenoxymethyl, group 2 (2-chlorophenoxy) ethyl, 2- (3-chlorophenoxy) ethyl group, 2- (4-chlorophenoxy) ethyl group, 2- (3,4-dichlorophenoxy) ethyl group, 2 (4-fluorophenoxy) ethyl group, 4-isopropylphenoxymethyl group, group 4-n -butylphenoxymethyl, 4-methylphenoxymethyl group, 2-methylphenoxymethyl group, 3-methylphenoxymethyl group, 4-n-propylphenoxymethyl group, 4-isopropylphenoxymethyl group, 2, 4-dimethylphenoxymethyl group, 2-3-dimethyl-phenoxymethyl group, group 2, 6- dimethylol enoxymethyl, group 3, 5-dimethyl-phenoxymethyl, group 2, 5-dimethyl-phenoxymethyl, group 2, 4,6-trimethyl-phenoxymethyl, group 2, 4,6-trimethyl-phenoxymethyl, group 4 -hexyl-enoxymethyl, group 2- (3 -methyl-enoxi) ethyl, 2- (3,4-dimethyl-enoxy) ethyl group, 3,5-ditrif luoromethyl-phenoxymethyl group, 2, 3, 4, 5, 6-pentaf luorofenoxymethyl group, 4-isopropoxy enoxy group methyl, 4-n-butoxy-enoxymethyl group, 4-methoxyphenoxymethyl group, 2-methoxy-enoxymethyl group, 3-methoxy-enoxymethyl group, 2- (3-methoxy-enoxy) ethyl group, 2- (4-methoxy-enoxy) -ethyl group 2- (3, 4-dimethoxy-enoxy) ethyl, group 2, 4-dimethoxy-enoxymethyl, group 2, 3-dimethoxy-enoxymethyl, group 3, 4-dimethoxy-enoxymethyl, group 2, 6-dimethoxy-enoxymethyl, group 3, 5-dimethoxy enoxymethyl, group 2, 5-dimethoxy-enoxymethyl, group 2, 4,6-trimethoxy-enoxymethyl, group 3, 4, 5-trimethoxy-enoxymethyl, group 3, 5-ditrif-loromethoxy-enoxymethyl, group 2-isopropoxy-enoxymethyl, group 3-chloro- 4-methoxy-enoxymethyl, 2-chloro-4-methoxy-enoxymethyl group, 2-chloro-4-trifluoromethoxy-enoxymethyl group, 3-methyl-4-fluorophenoxymethyl group, group 4-bromo-3-trif luoromethyl-phenoxymethyl, group 2- (4-f luorof enoxi) ethyl, group 3- (4-f luor of enoxi) propyl, group 4 - (4-fluoro-enoxy) butyl, group 5 - (-fluorofenoxi) pentyl, 6- (4-fluorophenoxy) hexyl group, 4-chlorofenoxymethyl group, 3- (4-chlorophenoxy) propyl group, 4- (4-chlorofenoxyl) butyl group 5- ( 4-chloro-enoxy) -pentyl, 6- (4-chloro-enoxy) -hexyl group, 4-methylphenoxymethyl group, 2- (4-methyl-enoxy) -ethyl group, 2- (2-isopropyl-enoxy) -ethyl group, 2- (4-methyl) group -isopropyl enoxi) ethyl, 2- (4-hexylphenoxy) ethyl group, 2- (2-fluoro-5-methylphenoxy) ethyl group, 2- (2-chloro-4-methoxyphenoxy) ethyl group, 2- (3-) group fluoro-4-chlorophenoxy) ethyl, 2- (3, 4, 5-trimethylphenoxy) ethyl group, 3- (4-methylphenoxy) propyl group, 4- (4-methylphenoxy) butyl group, 5- (4-methylphenoxy) group Pentyl, 6- (4-methylphenoxy) hexyl group, group 4-trifluoromethylphenoxymethyl, 2-trifluoromethylphenoxymethyl group, 3-trifluoromethylphenoxymethyl group, 2- (4-trifluoromethylphenoxy) ethyl group, 2- (2-trifluoromethylphenoxy) ethyl group, 2- (3-trifluoromethylphenoxy) ethyl group, 3- (4-) group trifluoromethylphenoxy) propyl, 4- (4-trifluoromethylphenoxy) butyl group, 5- (4-trifluoromethylphenoxy) pentyl group, 6- (4-trifluoromethylphenoxy) hexyl group, 4-trifluoromethoxyphenoxymethyl group, 2- (4-trifluoromethoxyphenoxy) ethyl group 2- (3-trifluoromethoxyphenoxy) ethyl, 2- (2-trifluoromethoxyphenoxy) ethyl group, 3- (4-trifluoromethoxyphenoxy) propyl group, 4- (4-trifluoromethoxyphenoxy) butyl group, 5- (4-trifluoromethoxyphenoxy) pentyl group 6- (4-trifluoromethoxyphenoxy) hexyl, 4-methoxyphenoxymethyl group, 2-isopropoxyphenoxymethyl group, 2- (4-methoxyphenoxy) ethyl group, 3- (4-methoxyphenoxy) propyl group, 4- (4-methoxyphenoxy) butyl group 5- (-methoxyphenoxy) pentyl, 6- (4-methoxyphenoxy) hexyl group or the like. A C 1 -C 6 alkyl thiazolyl group (wherein, in the thiazole ring, at least one phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted) includes a C 1 -C 6 alkyl thiazolyl group (wherein, in the thiazole ring, 1 or 2 phenyl groups [ wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a substituted C1-Cβ alkoxy group or not substituted with halogen can be substituted] can be substituted), for example, a 2-thiazolylmethyl group, 4-thiazolylmethyl group, 5-thiazolylmethyl group, 5-phenyl-4-thiazolylmethyl group, 4-phenyl-5-thiazolylmethyl group, group 2-phenyl-4-thiazolylmethyl, 2-phenyl group l-5-thiazolylmethyl, group 2, 5-diphenyl-4-thiazolylmethyl, group 2, 4-diphenyl-5-thiazolylmethyl, 5- (2-fluorophenyl) -4-thiazolylmethyl group, 4- (2-fluorophenyl) - group 5-thiazolylmethyl, 2- (2-chlorophenyl) -4-thiazolylmethyl group, 2- (2-bromophenyl) -5-thiazolylmethyl group, 2- (2, 3, 4, 5, 6-pentafluorophenyl) -4-thiazolylmethyl group , 2- (2-bromophenyl) -5- thiazolylmethyl group, 5- (3-iodophenyl) -4-thiazolylmethyl group, 4- (3-fluorophenyl) -5-thiazolylmethyl group, 2- (2, 3-difluorophenyl) group -4-thiazolylmethyl, 2- (3-bromophenyl) -5-thiazolylmethyl group, 2- (3, 4, 5-trifluorophenyl) -4- thiazolylmethyl group, 2- (3-fluorophenyl) -5-thiazolylmethyl group, group 5 - (2,4,6-trichlorophenyl) -4-thiazolylmethyl group 4- (2, 3, 4, 5, ß-pentafluorophenyl) -5-thiazolylmethyl group 2- (4-fluorophenyl) -4-thiazolylmethyl group 4- (2-fluorophenyl) -5-thiazolylmethyl, 2- (4-fluorophenyl) -5-thiazolylmethyl group, 5- (2-chlorophenyl) -4-thiazolylmethyl group, 4- (2-chlorophenyl) -5-thiazolylmethyl group , group 2- (2-chlorof enyl) -5-thiazolylmethyl, 5- (3-methylphenyl) -4-thiazolylmethyl group, 4- (3-ethylphenyl) -5-thiazolylmethyl group, 2- (3-propylphenyl) -4-thiazolylmethyl group, group 2- ( 2-n-butylphenyl) -5-thiazolylmethyl, 2- (3-n-pentylphenyl) -4-thiazolylmethyl group, 2- (3-n-hexylphenyl) -5-thiazolylmethyl group, 5- (3,4-dimethylphenyl) group ) -4-thiazolylmethyl, 4- (2,4,6-trimethylphenyl) -5-thiazolylmethyl group, 2- (4-methoxyphenyl) -4-thiazolylmethyl group, 2- (4-ethoxyphenyl) -5-thiazolylmethyl group, group 2- (4-propoxyphenyl) -4-thiazolylmethyl, 2- (4-n-butoxyphenyl) -5-thiazolylmethyl group, 2- (2-thiazolyl) ethyl group, 2- (4-thiazolyl) ethyl group, 2- group (5-thiazolyl) ethyl, 2- (5- (2-n-pentyloxyphenyl) -4-thiazolyl] ethyl group, 2- (2- (2-n-hexyloxyphenyl) -5-thiazolyl] ethyl group 2- (2- (2,5-dimethoxyphenyl) -4-thiazolyl] ethyl, 2- (2- (2,4-, 6-trimethoxyphenyl) -5-thiazolyl] ethyl group, 2- (2-trifluoromethylphenyl) -4- group thiazolylmethyl, 2,4-di (trifluoromethyl) phenyl-5-thiazolylmethyl group, 2-trifluoromethoxy group nyl-4-thiazolylmethyl, 2,3-di (trifluoromethoxy) phenyl-5-thiazolylmethyl group, 2- (2-methyl-5-trifluoromethoxyphenyl-4-thiazolyl) ethyl group, 3- (2-thiazolyl) propyl group, 2- (4-thiazolyl) propyl group, 3- (5-thiazolyl) propyl group 3- ((2-methoxy-4-trifluoromethylphenyl) -4-thiazolyl]] propyl, 4- (2-thiazolyl) butyl group, 4- (4-thiazolyl) butyl group, 3- (5-thiazolyl) butyl group, 4- (4- (2-Chloro-4-methylphenyl) -2-thiazolyl] butyl group, 5- (2-thiazolyl) pentyl group, 5- (5- (2-fluoro-3-methoxyphenyl) -2- group thiazolyl] pentyl, 5- (4-thiazolyl) pentyl group, 5- (5-thiazolyl) pentyl group, 5- (2-thiazolyl) hexyl group, 5- (4-thiazolyl) hexyl group, group 5- (5- thiazolyl) hexyl or the like A C 1 -C 6 alkoxycarbonyl group is a group composed of a C 1 -C 6 alkoxy group as defined above and a carbonyl group, examples of which include a methoxycarbonyl group, ethoxycarbonyl group, propoxycarbonyl group, isopropoxycarbonyl group, n-butoxycarbonyl group, isobutoxycarbonyl group, tert-butoxycarbonyl group, sec-butoxycarbonyl group, n-pentox group icarbonyl, neopentoxycarbonyl group, n-hexyloxycarbonyl group, isohexyloxycarbonyl group, 3-methylpentoxycarbonyl group or the like.

A benzoyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) includes a benzoyl group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), for example, a benzoyl group, 2-fluorobenzoyl group, 3-fluorobenzoyl group, 4-fluorobenzoyl group, 2, 3-difluorobenzoyl group 3, 4-difluorobenzoyl, 2-chlorobenzoyl group, 3-chlorobenzoyl group, 4-chlorobenzoyl group, 2,3-dichlorobenzoyl group, 3-dichlorobenzoyl group, 2,4,6-trichlorobenzoyl group, 4-iodobenzoyl group, group 2, 3,4,5,6-pentafluorobenzoyl, group 2 bromobenzoyl, 3-bromobenzoyl group, 4-bromobenzoyl group, 2,3-dibromobenzoyl group, 3, 4-dibromobenzoyl group, 2-methylbenzoyl group, 3-methylbenzoyl group, 4-methylbenzoyl group, 2-3-dimethylbenzoyl group 3 , 4-dimethylbenzoyl group, 3, 4, 5-trimethylbenzoyl-2 trifluoromethylbenzoyl, group, 3-trifluoromethylbenzoyl, 4-trifluoromethylbenzoyl group, group 2, 3-ditrifluorometilbenzoilo, 3,4- ditrifluorometilbenzoilo group, 2-methoxybenzoyl group, group 3 -methoxybenzoyl group, 4-methoxybenzoyl, 3,4-dimethoxybenzoyl group, group 2, 4, 6-trimethoxybenzoyl group, 2-trifluoromethoxybenzoyl group, 3-trifluoromethoxybenzoyl group, 4-trifluoromethoxybenzoyl group, 2-methoxy-3-fluorobenzoyl group, 3 -methyl-4-chlorobenzoyl, 3-trifluoromethoxy-4-methylbenzoyl group, 2-methoxy-4-trifluoromethylbenzoyl group or the like. A phenylcarbamoyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted or unsubstituted Cl-Cβ alkoxy group halogen can be substituted) is a group composed of an aniline which can be substituted on the phenyl ring by 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or not substituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, an N-C1-C6 alkylaniline or a Cl-Cβ N-phenyl alkylaniline and a carbonyl group, examples of which include a phenylcarbamoyl group, group 2 fluorophenylcarbamoyl, 3-fluorophenylcarbamoyl group, 4-fluorophenylcarbamoyl group, 2-chlorophenylcarbamoyl group, 3-chlorophenylcarbamoyl group, 4-chlorophenylcarbamoyl group, 2-bromophenylcarbamoyl group, 3-bromophen group ilcarbamoilo group, 4-bromofenilcarbamoilo group, 2-yodofenilcarbamoilo group, 3-yodofenilcarbamoilo group, 4-yodofenilcarbamoilo, group 2, 3-difluorophenylcarbamoyl group, 3,4-difluorophenylcarbamoyl group, 3, 5-difluorophenylcarbamoyl group, 2, 4-difluorophenylcarbamoyl, 2,6-difluorophenylcarbamoyl group, group 2, 3-diclorofenilcarbamoilo, group 3, 4-diclorofenilcarbamoilo group, 3,5-diclorofenilcarbamoilo, group 2, 4-diclorofenilcarbamoilo, group 2, 6-diclorofenilcarbamoilo, 3,4,5-group trifluorofenilcarbamoilo , 2,3,4,5,6-pentafluorofenilcarbamoilo group, 3,4,5-triclorofenilcarbamoilo group, group 2, 4, 6-trifluorofenilcarbamoilo, group 2, 4, 6-triclorofenilcarbamoilo group, 2-metilfenilcarbamoilo group, 3-metilfenilcarbamoilo group, 4-metilfenilcarbamoilo group, 2-methyl-3-clorofenilcarbamoilo group, 3-methyl-4-clorofenilcarbamoilo group, 2-chloro-4-metilfenilcarbamoilo group, 2-methyl-3-fluorofenilcarbamoilo group, 2-trifluorometilfenilcarbamoilo, group 3- trifluoromethylphenylcarbamoyl or, N-methyl-N-phenylcarbamoyl group, N- (2-fluorophenyl) -N-methylcarbamoyl group, N- (3-fluorophenyl) -N-methylcarbamoyl group, N- (4-fluorophenyl) -N-methylcarbamoyl group, N- (2-chlorophenyl) -N-methylcarbamoyl group, N- (3-chlorophenyl) -N-methylcarbamoyl group, N- (4-chlorophenyl) -N-methylcarbamoyl group, N- (4-bromophenyl) -N-methylcarbamoyl group, N- (2-iodophenyl) -N group - methylcarbamoyl, N- (3-iodophenyl) -N-methylcarbamoyl group, N- (4-iodophenyl) -N-methylcarbamoyl group, N- (2,3-difluorophenyl) -N-methylcarbamoyl group, N- group (3, 4-difluorophenyl) -N-methylcarbamoyl, N- (3,5-difluorophenyl) -N-methylcarbamoyl group, N- (2,4-difluorophenyl) -N-methylcarbamoyl group, N- (2,6-difluorophenyl) - group N-methylcarbamoyl, N- (2,3-dichlorophenyl) -N-methylcarbamoyl group, N- (3,4-dichlorophenyl) -N-methylcarbamoyl group, N- (3,5-dichlorophenyl) -N-methylcarbamoyl group, group N- (2,4-dichlorophenyl) -N-methylcarbamoyl, N- (2,6-dichlorophenyl) -N-methylcarbamoyl group, N- (3,4,5-trifluorophenyl) -N-methylcarbamoyl group, N- group ( 3,4,5-trichlorophenyl) -N-methylcarbamoyl, N- (2,4,6-trifluorophenyl) -N-methylcarbamoyl group, N- (2,4,6-trichlorophenyl) -N-methylcarbamoyl group, group N- (2-methylphenyl) -N-methylcarbamoyl or, N- (3-methylphenyl) -N-methylcarbamoyl group, N- (4-methylphenyl) -N-methylcarbamoyl group, N- (2-methyl-3-chlorophenyl) -N-methylcarbamoyl group, N- group (3 -methyl-4-chlorophenyl) -N-methylcarbamoyl, N- (2-chloro-4-methylphenyl) -N-methylcarbamoyl group, N- (2-methyl-3-fluorophenyl) -N-methylcarbamoyl group, N- group ( 2-trifluoromethylphenyl) -N-methylcarbamoyl, N- (4-trifluoromethylphenyl) -N-methylcarbamoyl group, N-benzyl-N-phenylcarbamoyl group, N-benzyl-N- (2-fluorophenyl) carbamoyl group, N-benzyl group N- (3-fluorophenyl) carbamoyl, N-benzyl-N- (4-fluorophenyl) carbamoyl group, N-benzyl-N- (2-chlorophenyl) carbamoyl group, N-benzyl-N- (3-chlorophenyl) carbamoyl group , N-benzyl-N- (4-chlorophenyl) carbamoyl group, N-benzyl-N- (2-bromophenyl) carbamoyl group, N-benzyl-N- (3-bromophenyl) carbamoyl group, N-benzyl-N- group (4-bromophenyl) carbamoyl, N-benzyl-N- (2-iodophenyl) carbamoyl group, N-benzyl-N- (3-iodophenyl) carbamoyl group, N-benzyl-N- (4-iodophenyl) carbamoyl group, group N-benzyl-N- (2,3-diflu) orophenyl) carbamoyl, N-benzyl-N- (3,4-difluorophenyl) carbamoyl group, N-benzyl-N- (3,5-difluorophenyl) carbamoyl group, N-benzyl-N- (2,4-difluorophenyl) group carbamoyl, N-benzyl-N- (2,6-difluorophenyl) carbamoyl group, N-benzyl-N- (2,3-dichlorophenyl) carbamoyl group, N-benzyl-N- (3,4-dichlorophenyl) carbamoyl group, N-benzyl-N- (3,5-dichlorophenyl) carbamoyl group, N-benzyl-N- (2,4-dichlorophenyl) carbamoyl group, N-benzyl-N- (2,6-dichlorophenyl) carbamoyl group, N group -benzyl-N- (3,4,5-trifluorophenyl) carbamoyl, N-benzyl-N- (3,4,5-trichlorophenyl) carbamoyl group, N-benzyl-N- (2,4,6-trifluorophenyl) group carbamoyl, N-benzyl-N- (2,4,6-trichlorophenyl) carbamoyl group, N-benzyl-N- (2-methylphenyl) carbamoyl group, N-benzyl-N- (3-methylphenyl) carbamoyl group, N group -benzyl-N- (4-methylphenyl) carbamoyl, N-benzyl-N- (2-methyl-3-chlorophenyl) carbamoyl group, N-benzyl-N- (3-methyl-4-chlorophenyl) carbamoyl group, N group -benzyl-N- (2-chloro-4-methylphenyl) carbamoyl, N-benzyl-N- (2-methyl-3-fluorophenyl) group ) carbamoyl, N-benzyl-N- (2-trifluoromethylphenyl) carbamoyl group, N-benzyl-N- (3-trifluoromethylphenyl) carbamoyl group, N-benzyl-N- (4-trifluoromethylphenyl) carbamoyl group, 2-pentafluoroethylphenylcarbamoyl group, 3-pentafluoroethylcarbamoyl group, 4-pentafluoroethylphenylcarbamoyl group, 2-isopropylphenylcarbamoyl group, 3-isopropylphenylcarbamoyl group, 4-isopropylphenylcarbamoyl group, 2-tert-butylphenylcarbamoyl group, 3-tert-butylphenylcarbamoyl group, 4-tert-butylphenylcarbamoyl group, 2-sec group -butylphenylcarbamoyl, 3-sec-butylphenylcarbamoyl group, 4-sec-butylphenylcarbamoyl group, 2-n-heptafluoropropylphenylcarbamoyl group, 3-n-heptafluoropropylphenylcarbamoyl group, 4-n-heptafluoropropylphenylcarbamoyl group, 4-pentylphenylcarbamoyl group, 4-hexylphenylcarbamoyl group, group 2 , 4-dimethylphenylcarbamoyl, 2,4,6-trimethylphenylcarbamoyl group, 3, 4-dimethoxyphenylcarbamoyl group, 3, 4, 5-trimethoxyphenylcarbamoyl group, 2-methoxyphenylcarbamoyl group, 3-methoxyphenylcarbon group bamoilo, 4-methoxyphenylcarbamoyl group, 2-methoxy-3-chlorophenylcarbamoyl group, 2-fluoro-3-methoxyphenylcarbamoyl group, 2-fluoro-4-methoxyphenylcarbamoyl group, 2,6-dimethoxyphenylcarbamoyl group, 2, 3,4-trifluorophenylcarbamoyl group 3, 4, 5-trifluorofenilcarbamoilo group trifluorometoxifenilcarbamoilo 2-, 3- group trifluorometoxifenilcarbamoilo group, 4-trifluorometoxifenilcarbamoilo group, 2-pentafluoroetoxifenilcarbamoilo group, 3-pentafluoroetoxifenilcarbamoilo group, 4-pentafluoroetoxifenilcarbamoilo group, 2-isopropoxifenilcarbamoilo group, 3-isopropoxifenilcarbamoilo, group 4 -isopropoxyphenylcarbamoyl, 2-tert-butoxyphenylcabamoyl group, 3-tert-butoxyphenylcabamoyl group, 4-tert-butoxyphenylcabamoyl group, 2-sec-butoxyphenylcabamoyl group, 3-sec-butoxyphenylcabamoyl group, 4-sec-butoxyphenylcabamoyl group, group 2-n- heptafluoropropoxyphenylcarbamoyl, 3-n-heptafluoropropoxyphenylcarbamoyl group, 4-n-heptafluoropropoxyphenylcarbamoyl group, 4-n-pentyloxyphenylcarbamoyl group, group 4-n-hexyloxyphenylcarbamoyl or the like. A benzothiazolyl group (wherein, in the benzothiazole ring, 1 to 3 C 1 -C 6 alkyl groups can be substituted) includes a benzothiazolyl group (wherein, in the benzothiazole ring, at least one Cl-Cß alkyl group can be substituted), for example, a group (2-, 4-, 5-, 6- or 7-) benzothiazolyl, 2-methyl-5-benzothiazolyl group, 4-ethyl-6-benzothiazolyl group, 5-propyl-7-benzothiazolyl group, 6-tert-butyl-2-benzothiazolyl group, 7-pentyl-4-benzothiazolyl group, 2-hexyl-5-benzothiazolyl group, 2, 4-dimethyl-5-benzothiazolyl group, 2, 4, 6-trimethyl-7 group -benzothiazolyl or the like. A 2,3-dihydro-lH-indenyl group (wherein, in the 2, 3-dihydro-lH-indene ring, at least one oxo group can be substituted) includes a 2,3-dihydro-lH-indenyl group ( wherein, in the 2, 3-dihydro-lH-indene ring, 1 or 2 oxo groups can be substituted), for example, a 2,3-dihydro-lH-indenyl group, l-oxo-2, 3- group dihydro-lH-indenyl, 1,3-dioxo-2,3-dihydro-lH-indenyl group or the like. A C2-C6 alkenyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a substituted Cl-Cß alkoxy group or not substituted by halogen can be substituted) is a group composed of 1 or 2 phenyl groups unsubstituted or substituted by 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a C1-Cβ alkoxy group substituted or unsubstituted with halogen and an alkenyl group containing 2 to 6 carbon atoms and having 1 to 3 double bonds. The C2-C6 alkenyl group phenyl includes both trans and cis forms. Such C2-C6 alkenyl group phenyl includes a 2-phenylvinyl group, 3-phenyl-2-propenyl group (common name: cinnamyl group), group 3, 3-diphenyl-2-propenyl, 3-phenyl-2-methyl-2. -propenyl, 4-phenyl-2-butenyl group, 4,4-diphenyl-2-butenyl group, 4-phenyl-3-butenyl group, 4-phenyl-1,3-butadienyl group, 5-phenyl-1 group, 3, 5-hexatrienyl, 5-diphenyl-3-pentenyl group, 6,6-diphenyl-2-hexenyl group, 6-phenyl-1,3-hexadienyl group, 3- (2-fluorophenyl) -2- group propenyl, 3- (3-fluorophenyl) -2-propenyl group, 3- (4-fluorophenyl) -2-propenyl group, 3- (2,3-difluorophenyl) -2-propenyl group, 3- (2, 3) group , 4, 5, 6-pentafluorophenyl) -2-propenyl, 3- (2,4-difluorophenyl) -2-propenyl group, 3- (3,4-difluorophenyl) -2-propenyl group, group 3- (3, 5-difluorophenyl) -2-propenyl, 3- (2-chlorophenyl) -2-propenyl group, 3- (3-chlorophenyl) -2-propenyl group, 3- (4-chlorophenyl) -2-propenyl group 3 - (2, 3-dichlorophenyl) -2-propenyl, 3- (2,4-dichlorophenyl) -2-propenyl group, 3- (3, 4-dic) lorophenyl) -2-propenyl, group 3- (3,5-dichlorophenyl) -2-propenyl, 3- (2,6-dichlorophenyl) -2-propenyl group, 3- (3,6-dichlorophenyl) -2-propenyl group, 3- (3, 5,6-trichlorophenyl) -2-propenyl, 3- (2, 4, 5-trichlorophenyl) -2-propenyl group, 3- (2-bromophenyl) -2-propenyl group, 3- (3-bromophenyl) group - 2-propenyl, 3- (4-bromophenyl) -2-propenyl group, 3- (2-methylphenyl) -2-propenyl group, 3- (3-methylphenyl) -2-propenyl group, 3- (4-methylphenyl) group ) -2-propenyl, 3- (2-trifluoromethylphenyl) -2-propenyl group, 3- (2-fluoro-4-bromophenyl) -2-propenyl group, 3- (4-chloro-3-fluorophenyl) -2 group -propenyl, 3- (2, 3, 4-trichlorophenyl) -2-propenyl group, 3- (2,4,6-trichlorophenyl) -2-propenyl group, 3- (4-ethylphenyl) -2-propenyl group, 3- (4-n-hexylphenyl) -2-propenyl group, 3- (4-isopropylphenyl) -2-propenyl group, 3- (4-n-butylphenyl) -2-propenyl group, 3- (2, 4) group -dimethylphenyl) -2-propenyl, 3- (2,3-dimethylphenyl) -2-propenyl group, 3- (2,6-dimethylphenyl) -2-propenyl group, 3- (3,5-dimethyl) group enyl) -2-propenyl, 3- (2,5-dimethylphenyl) -2-propenyl group, 3- (2,4,6-trimethylphenyl) -2-propenyl group, 3- (3,5-ditrifluoromethylphenyl) - group 2-propenyl, 3- (4-n-butoxyphenyl) -2-propenyl group, 3- (2,4-dimethoxyphenyl) -2-propenyl group, 3- (2,3-dimethoxyphenyl) -2-propenyl group 3- (2,6-dimethoxyphenyl) -2-propenyl, 3- (3,5-dimethoxyphenyl) -2-propenyl group, 3- (2,5-dimethoxyphenyl) -2-propenyl group, group 3- (3, 5-ditrifluoromethoxyphenyl) -2-propenyl, 3- (3-chloro-4-methoxyphenyl) -2-propenyl group, 3- (2-chloro-4-trifluoromethoxyphenyl) -2-propenyl group, 3- (3-methyl) group -4-fluorophenyl) -2-propenyl, 3- (2-methyl-4-fluorophenyl) -2-propenyl group, 3- (3-trifluoromethyl-4-fluorophenyl) -2-propenyl group, 3- (3-) group trifluoromethyl-2-fluorophenyl) -2-propenyl, 3- (4-bromo-3-trifluoromethylphenyl) -2-propenyl group, 3- (4-chloro-3-trifluoromethylphenyl) -2-propenyl group 3- (3 -trifluoromethylphenyl) -2-propenyl, 3- (2-trifluoromethylphenyl) -2-propenyl group, 3- (4-tri) group fluoromethylphenyl) -2-propenyl, 3- (2-trifluoromethoxyphenyl) -2-propenyl group, 3- (3-trifluoromethoxyphenyl) -2-propenyl group, 3- (4-trifluoromethoxyphenyl) -2-propenyl group, 3- ( 2-methoxyphenyl) -2-propenyl, 3- (3-methoxyphenyl) -2-propenyl group, 3- (4-methoxyphenyl) -2-propenyl group, 3- (4-n-hexyloxyphenyl) -2-propenyl group, 3- (3, 4-dimethoxyphenyl) -2-propenyl group, 3- (3,5-dimethoxyphenyl) -2-propenyl group, 4- (4-chlorophenyl) -2-butenyl group, 4- (4-chlorophenyl) group ) -3-butenyl, 5- (4-chlorophenyl) -2-pentenyl group, 5- (4-chlorophenyl) -4-pentenyl group, 5- (4-chlorophenyl) -3-pentenyl group, group 6- (4) chlorophenyl) -5-hexenyl, 6- (4-chlorophenyl) -4-hexenyl group, 6- (4-chlorophenyl) -3-hexenyl group, 6- (4-chlorophenyl) -3-hexenyl group or the like. A phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a C1-C4 alkylenedioxy group, a cyano group, a nitro group, an amino group which may have a C1-C6 alkyl group as a substituent, an amino-substituted sulfonyl group which may have a C 1 -C 6 alkyl group as a substituent, a C 1 -C 6 alkoxycarbonyl group, an alkylthio Cl-Cß group, a phenoxy group, a Cl-Cβ phenyl alkoxy group, a pyrrolidinyl group (wherein, in the pyrrolidine ring, at least one oxo group can be substituted), an imidazolyl group, an isooxazolyl group, an oxazolyl group, a Cl-Cβ phenyl alkyl group, a phenyl group, a Cl-alkyl group Cß amino which can have a Cl-Cß alkyl group as a substituent, a Cl-Cβ pyrrolidinyl alkoxy group, a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted Cl-Cβ alkoxy group or not replaced with halogen can be replaced) incl. in addition to a phenyl group as described above (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen and an alkoxy group Cl-Cß substituted or unsubstituted with halogen can be substituted), a phenyl group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a C 1 -C 4 alkylenedioxy group as described above, a cyano group, a nitro group, an amino group which may have 1 or 2 C1-C6 alkyl groups as a substituent as described below, an amino-substituted sulfonyl group which may have 1 or 2 Cl-Cß alkyl groups as a substituent as described above, an alkoxycarbonyl group Cl-Cβ as described later, an alkylthio Cl-Cß group as described later, a phenoxy group, a Cl-Cβ phenyl alkoxy group as described above, a pyrrolidinyl group as described above (wherein, in the pyrrolidine ring, at least one oxo group can be substituted), an imidazolyl group, an isooxazolyl group, an oxazolyl group, a Cl-Cβ phenyl alkyl group as described above, a phenyl group, a Cl-Cß amino alkyl group which You can have a Cl-Cß alkyl group as a substituent as described later, a Cl-Cβ pyrrolidinyl alkoxy group as described above, a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), for example, a 4-cyanophenyl group, 3-cyanophenyl group, 2-cyanophenyl group, 3-cyano-phenyl group, 2, 4,6-tricyclo-phenyl, 4-nitrophenyl group , 3-nitrophenyl group, 2-nitrophenyl group, 3-dinitrophenyl group, 2, 4, ß-trinitrophenyl group, 4-dimethylaminophenyl group, 3-methylaminophenyl group, 2-N-ethyl-N-methylaminophenyl group 2 , 4-di (methylamino) phenyl, 2,4,6-tri (methylamino) phenyl group, 4-dimethylaminosulfonylphenyl group, 3-methylaminosulfonylphenyl group, 2-N-ethyl-N-methylaminosulfonylphenyl group, 2,4-di ( methylaminosulfonyl) phenyl, 2,4,6-tri (methylaminosulfonyl) phenyl group, 4-ethoxycarbonylphenyl group, 4-ethoxycarbonylphenyl group, 3-methoxycarbonylphenyl group, 2-propoxycarbonylphenyl group, 2,4-diethoxycarbonylphenyl group, 2, 4,6-triethoxycarbonylphenyl group, 4-methylthiophenyl group, 3-ethylthiophenyl group, 2-methylthiophenyl group, 3, 4-dimethylthiophenyl group 2 , 4,6-trimethylthiophenyl, group 3, 4-ethylenedioxyphenyl, 3,4-methylenedioxyphenyl group, 4-diisopropylaminomethylphenyl group, 3-methylaminomethylphenyl group, 2-ethylaminomethylphenyl group, 2, 4-dimethylaminomethylphenyl group 2,4,6- triethylaminomethylphenyl, 4-phenoxyphenyl group, 3-phenoxyphenyl group, 2-phenoxyphenyl group, 2,4-diphenoxyphenyl group, 3, 4, 5-trifenoxyphenyl group, 4-benzyloxyphenyl group, 3-benzyloxyphenyl group, 2-benzyloxyphenyl group 2 , 4-dibenzyloxyphenyl, 2,4,6-tribenzyloxyphenyl group, 4- (2-oxo-l-pyrrolidinyl) phenyl group, 4- (5-oxazolyl) phenyl group, 4- (5-isooxazolyl) phenyl group 4 - (1-imidazolyl) phenyl, 4-benzylphenyl group, group 3-benzylphenyl, 2-benzylphenyl group, 3,4-dibenzylphenyl group, 2, 4,6-tribenzylphenyl group, 4-biphenyl group, 3-biphenyl group, 2-biphenyl group, 2,4-diphenylphenyl group 2 , 4,6-triphenylphenyl, 2- (2-imidazolyl) -4-phenoxyphenyl group, 3- (2-oxazolyl) -4-benzyloxyphenyl group, 4- (3-isooxazolyl) -2-benzylphenyl group or the like.

A phenyl group [wherein, in the phenyl ring, a halogen can be substituted] includes a phenyl group which can be substituted by 1 to 5 halogen atoms in the phenyl ring, for example, a phenyl group, 2-fluorophenyl group, 3-fluorophenyl group, 4-fluorophenyl group, 2-chlorophenyl group, 3-chlorophenyl group, 4-chlorophenyl group, 2-bromophenyl group, 3-bromophenyl group, 4-bromophenyl group, 2-iodophenyl group, 3-iodophenyl group, 4-iodophenyl group, 2,3-difluorophenyl group, 3,4-difluorophenyl group, 3-difluorophenyl group, 2,4-difluorophenyl group, 2,6-difluorophenyl group, 2,3-dichlorophenyl group 3 group 4-dichlorophenyl, 3,5-dichlorophenyl group, 2-dichlorophenyl group, 2,6-dichlorophenyl group, 3, 4, 5-trifluorophenyl group, 3,4,5-trichlorophenyl group, group 2, 4, 6 trifluorophenyl, 2,4,6-trichlorophenyl group, 2-fluoro-4-bromophenyl group, 4-chloro-3-fluorophenyl group, 2,3-trichlorophenyl group, 3,4,5-trifluorophenyl group, group 2, 4 , 6-tribromophenyl, gr upo 2,3,4,5,6-pentafluorophenyl or the like. A C1-C6 alkyl group substituted with C1-C5 alkoxy phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a C1-C4 alkylenedioxy group, a halogen atom, a cyano group, a phenyl group , a C1-C6 alkoxy phenyl group, a C2-C6 alkenyl group phenyl, a phenoxy group, a C1-C6 alkylthio group, a C1-C3 alkyl group substituted or unsubstituted with halogen and a C1-C3 alkoxy group substituted or not substituted with halogen can be substituted) includes, in addition to a Cl-Cß alkyl group substituted with Cl-Cβ phenyl alkoxy as described above (wherein, in the phenyl group, at least one selected from the group consisting of a halogen atom , a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cß alkyl group substituted with Cl-Cß phenyl alkoxy (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents (preferably 1 or 2 substituents if the substituent is a C1-C4 alkylenedioxy group) selected from the group consisting of a straight or branched alkylenedioxy group containing 1 to 4 carbon atoms in the alkyl part as described above or later, a halogen atom, a cyano group, a phenyl group, a phenylalkoxy group having a straight or branched alkoxy containing 1 to 6 carbon atoms in the alkoxy part, a phenylenekenyl group which is composed of an alkenyl group containing 2 to 6 carbon atoms and having at least 1 to 3 double bonds includes both trans and cis forms, a phenoxy group, a straight or branched Cl-Cβ alkyl group containing 1 to 6 carbon atoms, a Cl-Cβ alkyl group straight or branched, substituted or unsubstituted with halogen containing 1 to 6 carbon atoms and a straight or branched Cl-Cβ alkoxy group substituted or unsubstituted with halogen containing 1 has 6 carbon atoms can be substituted), for example, a 4-cyanophenylmethoxymethyl group, 3-cyanophenylmethoxymethyl group, 2-cyano-phenylmethoxymethyl group, 2-cyano-phenoxymethoxymethyl group, 2, 4,6-tricyclo-phenylmethoxymethyl group, 4-biphenylmethoxymethyl group, 3-biphenylmethoxymethyl group, 2-biphenylmethoxymethyl group, 2,4-diphenylphenylmethoxymethyl group, 2, 4, 3-triphenylphenylmethoxymethyl group, 4-phenoxyphenylmethoxymethyl group, 3-phenoxyphenylmethoxymethyl group, 2-phenoxyphenylmethoxymethyl group, 3,4-diphenoxyphenylmethoxymethyl group, group 3, 4,5-Triphenoxyphenylmethoxymethyl, 4-methylthiophenylmethoxymethyl group, 3-ethylthiophenylmethylmethyl group, 2-methylthiophenylmethoxymethyl group, 2,4-dimethylthiophenylmethoxymethyl group, 2,4,6-trimethylthiophenylmethoxymethyl group, 4-cyano-2-phenylphenylmethoxymethyl group, 3-phenoxy-4-methylthiophenylmethoxymethyl group, 3-trifluoromethyl-4-methylthiophenylmethoxymethyl group, group 3-trifluoromethoxy-2- fenoxifenilmetoximetilo, 3,4-metilendioxifenilmetoximetilo group, 4-benciloxifenilmetoximetilo, 3,4-dibenciloxifenilmetoximetilo, group 2, r4,6-tribenciloxifenilmetoximetilo group, 3-benciloxifenilmetoximetilo group, 2-benciloxifenilmetoximetilo group, 4-estirilfenilmetoximetilo , 3-styrylphenylmethoxymethyl group, 2-styrylphenylmethoxymethyl group, 2,4-diethyrylphenylmethoxymethyl group, 2,4,6-tristyrylphenylmethoxymethyl group or the like. A Cl-Cß phenyl alkoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a cyano group, a phenyl group, a Cl-Cβ alkoxycarbonyl group, a phenoxy group, an alkylthio Cl-Cβ group , a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted) includes, in addition to a Cl-Cß phenyl alkoxy group as described above (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted), a C1-C6 alkoxy group substituted by 1 or 2 phenyl groups (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a cyano group, a phenyl group, a group C1-C6 alkoxycarbonyl as described above, a phenoxy group, a C1-C6 alkylthio group as described above, a halogen atom, a substituted or unsubstituted C1-C6 alkyl group with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can to be substituted), for example, a 4-cyanophenylmethoxy group, 3-cyanobenzyloxy group, 2-cyanobenzyloxy group, 2-cyanobenzyloxy group, 2,3,4-tricyanobenzyloxy group, 4-biphenylmethoxy group, 3-biphenylmethoxy group, group 2-biphenylmethoxy, 2,4-diphenylbenzyloxy group, 2, 4,6-triphenylbenzyloxy group, 4-methoxycarbonylbenzyloxy group, 3-ethoxycarbonylbenzyloxy group, 2-methoxycarbonylbenzyloxy group, 3,4-diethoxycarbonylbenzyloxy group, 3,4,5-trimethoxycarbonylbenzyloxy group , 3-phenoxybenzyloxy group, 2-phenoxybenzyloxy group, 4-phenoxybenzyloxy group, 2,4-diphenoxybenzyloxy group, 2, 4,6-trifenoxibenzyloxy group, 4-methylthiobenzyloxy group, 3-methylthiobenzyloxy group, 2-methylthiobenzyloxy group 3 group 4-dimethylthiobenzyloxy, group 2, 5, 6-trimethyl lthiobenzyloxy, 3-cyano-4-bibenzyloxy group, 4-ethoxycarbonyl-3-phenoxybenzyloxy group, 3-methylthio-4-ethylbenzyloxy group, di (4-trifluoromethoxyphenyl) methoxy group, di (4-trifluoromethylphenyl) methoxy group, di ( 4-chlorophenyl) methoxy, di (3-methoxyphenyl) ethoxy group, di (2-methylphenyl) ethoxy group, di (2,4-dimethoxyphenyl) methoxy group, di (3,4-dimethylphenyl) methoxy group, di (2) group , 4,6-trimethoxyphenyl) methoxy, di (3, 4, 5-trifluoromethylphenyl) methoxy group, di (2,4,6-trifluorophenyl) methoxy group, 1- (4-trifluoromethoxyphenyl) -1- (2, 4- dichlorophenyl) methoxy or the like. A C2-C6 alkenyloxy phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a substituted Cl-Cß alkoxy group or unsubstituted with halogen can be substituted) includes a group consisting of a phenyl group substituted or unsubstituted by 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-Cβ halogen alkyl group and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen and an alkenyl group containing 2 to ß carbon atoms and having at least 1 to 3 double bonds s. The C2-C6 alkenyloxy phenyl group includes both trans and cis forms. Such a C2-C6 alkenyloxy phenyl group includes a 2-phenylvinyloxy group, 3-phenyl-2-propenyloxy group (common name: cinnamyloxy group), 4-phenyl-2-butenyloxy group, 4-phenyl-3-butenyloxy group, 4-phenyl-1,3-butadienyloxy group, 5-phenyl group -1, 3, 5-hexatrienyloxy, 3- (2-fluorophenyl) -2-propenyloxy group, 3- (3-fluorophenyl) -2-propenyloxy group, 3- (4-fluorophenyl) -2-propenyloxy group, group 3 - (2,3-difluorophenyl) -2-propenyloxy, group 3- (2,3,3,5-b-pentafluorophenyl) -2-propenyloxy group 3- (2,4-difluorophenyl) -2-propenyloxy group 3- (3, 4-difluorophenyl) -2-propenyloxy, 3- (3,5-difluorophenyl) -2-propenyloxy group, 3- (2-chlorophenyl) -2-propenyloxy group, 3- (3-chlorophenyl) group -2-propenyloxy, 3- (4-chlorophenyl) -2-propenyloxy group, 3- (2,3-dichlorophenyl) -2-propenyloxy group, 3- (2,4-dichlorophenyl) -2-propenyloxy group, group 3 - (3,4-dichlorophenyl) -2-propenyloxy, 3- (3,5-dichlorophenyl) -2-propenyloxy group, 3- (2-bromophenyl) -2-propenyloxy group, 3- (3-bromophenyl) group - 2-propenyloxy, 3- (4-bromophenyl) -2-propenyloxy group, 3- (2-methyl) group nil) -2-propenyloxy, 3- (3-methylphenyl) -2-propenyloxy group, 3- (4-methylphenyl) -2-propenyloxy group, 3- (2-trifluoromethylphenyl) -2-propenyloxy group, group 3- ( 2-fluoro-4-bromophenyl) -2-propenyloxy, 3- (4-chloro-3-fluorophenyl) -2-propenyloxy group, 3- (2,3-trichlorophenyl) -2-propenyloxy group, group 3 (2, 4, ß-trichlorophenyl) -2-propenyloxy, 3- (4-isopropylphenyl) -2-propenyloxy group, 3- (4-n-butylphenyl) -2-propenyloxy group, 3- (2, 4-) group dimethylphenyl) -2-propenyloxy, 3- (2,3-dimethylphenyl) -2-propenyloxy group, 3- (2,6-dimethylphenyl) -2-propenyloxy group, 3- (3,5-dimethylphenyl) -2- group Propenyloxy, 3- (2, 5-dimethylphenyl) -2-propenyloxy group, 3- (2,4-trimethylphenyl) -2-propenyloxy group, 3- (3,5-ditrifluoromethylphenyl) -2-propenyloxy group 3- (4-n-butoxyphenyl) -2-propenyloxy, 3- (2,4-dimethoxyphenyl) -2-propenyloxy group, 3- (2,3-dimethoxyphenyl) -2-propenyloxy group, group 3- (2, 6-dimethoxyphenyl) -2-propenyloxy, 3- (3,5-dimethoxyphenyl) -2-propenyloxy group, group 3- (2, 5-dimethoxyphenyl) -2-propenyloxy, 3- (3,5-ditrifluoromethoxy-phenyl) -2-propenyloxy group, 3- (3-chloro-4-methoxyphenyl) -2-? -ropenyloxy group, 3- (2-chloro) group 4-trifluoromethoxyphenyl) -2-propenyloxy, 3- (3-methyl-4-fluorophenyl) -2-propenyloxy group, 3- (4-bromo-3-trifluoromethylphenyl) -2-propenyloxy group, 3- (3-trifluoromethylphenyl) group ) -2-propenyloxy, 3- (4-trifluoromethylphenyl) -2-propenyloxy group, 3- (2-trifluoromethoxyphenyl) -2-propenyloxy group, 3- (3-trifluoromethoxyphenyl) -2-propenyloxy group, group 3- (4) -trifluoromethoxyphenyl) -2-propenyloxy, 3- (2-methoxyphenyl) -2-propenyloxy group, 3- (3-methoxyphenyl) -2-propenyloxy group, 3- (4-methoxyphenyl) -2-propenyloxy group, group 3 (3, 4-dimethoxyphenyl) -2-propenyloxy, 3- (3,5-dimethoxyphenyl) -2-propenyloxy group, 4- (4-chlorophenyl) -2-butenyloxy group, 5- (4-chlorophenyl) -2 group -pentenyloxy, 4- (4-chlorophenyl) -3-butenyloxy group, 5- (4-chlorophenyl) -4-pentenyloxy group, 5- (4-chlorophenyl) -3-pentenyloxy group, 6- (4-chlorophenyl) group) -5-hexenyloxy, gr 6- (4-chlorophenyl) -4-hexenyloxy, 6- (4-chlorophenyl) -3-hexenyloxy group, 6- (4-chlorophenyl) -3-hexenyloxy group or the like. A C1-C6 alkyl group which may have a hydroxide group as a substituent includes, in addition to a Cl-Cß alkyl group as described above, a straight or branched Cl-Cß alkyl group which may have 1 to 3 hydroxide groups, for example, a hydroxymethyl group, a 2-hydroxyethyl group, a 1-hydroxyethyl group, a 3-hydroxypropyl group, a 2,3-dihydroxypropyl group, a 4-hydroxybutyl group, a 3,4-dihydroxybutyl group, a 1-l-dimethyl-2- group. hydroxyethyl, 5-hydroxypentyl group, 6-hydroxyhexyl group, 2-methyl-3-hydroxypropyl group, 2, 3, 4-trihydroxybutyl group or the like. A C1-Cß alkanoyl group includes a group derived from an aliphatic carboxylic acid containing 1 to 6 carbon atoms, examples of which include a formyl group, acetyl group, propionyl group, butyryl group, pentanoyl group, hexanoyl group or the like. An alkoxycarbonyl Cl-Cβ phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted] is a group consisting of a C1-C6 alkoxy phenyl group which can be substituted by 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen as defined above and a carbonyl group, examples of which include a benzyloxycarbonyl group, 2-phenylethoxycarbonyl group, 3-phenylpropoxycarbonyl group, 2-phenylpropoxycarbonyl group, 4-phenylbutoxycarbonyl group, group 5- phenylpentoxycarbonyl, 4-phenylpentoxycarbonyl group, 6-phenylhexyloxycarbonyl group, 2-fluorobenzyloxycarbonyl group, 3-fluorobenzyloxycarbonyl group, 4-fluorobenzyl group Iloxycarbonyl, 2- (2-fluorophenyl) ethoxycarbonyl group, 2- (3-fluorophenyl) ethoxycarbonyl group, 2- (4-fluorophenyl) ethoxycarbonyl group, 2-chlorobenzyloxycarbonyl group, 3-chlorobenzyloxycarbonyl group, 4-chlorobenzyloxycarbonyl group, group 2 fluoro-4-bromobenzyloxycarbonyl, 4-chloro-3-fluorobenzyloxycarbonyl group, 2,3,4-trichlorobenzyloxycarbonyl group, 3,4,5-trifluorobenzyloxycarbonyl group, 2,3,4,5,6-pentafluorobenzyloxycarbonyl group, group 2,4 , 6-trichlorobenzyloxycarbonyl, 4-isopropylbenzyloxycarbonyl group, 4-n-butylbenzyloxycarbonyl group, 4-methylbenzyloxycarbonyl group, 2-methylbenzyloxycarbonyl group, 3-methylbenzyloxycarbonyl group, 2, 4-dimethylbenzyloxycarbonyl group, 2,3-dimethylbenzyloxycarbonyl group, group 2,6 -dimethylbenzyloxycarbonyl, 3,5-dimethylbenzyloxycarbonyl group, 2,5-dimethylbenzyloxycarbonyl group, group 2, r4,6-trimethylbenzyloxycarbonyl, 3,5-ditrifluoromethylbenzyloxycarbonyl group, 4-isopropoxybenzyloxycarbonyl group, 4-n-butoxybenzyl group xicarbonyl, 4-methoxybenzyloxycarbonyl group, 2-methoxybenzyloxycarbonyl group, 3-methoxybenzyloxycarbonyl group, 2,4-dimethoxybenzyloxycarbonyl group, 2,3-dimethoxybenzyloxycarbonyl group, 2,6-dimethoxybenzyloxycarbonyl group, 3,5-dimethoxybenzyloxycarbonyl group, group 2,5- dimethoxybenzyloxycarbonyl, 2,4,6-trimethoxybenzyloxycarbonyl group, 3,5-ditrifluoromethoxybenzyloxycarbonyl group, 2-isopropoxybenzyloxycarbonyl group, irupo 3-chloro-4-methoxybenzyloxycarbonyl group,? 2-chloro-4-trifluoromethoxybenzyloxycarbonyl group, 3-methyl-4-fluorobenzyloxycarbonyl group, 4-bromo-3-trifluoromethylbenzyloxycarbonyl group, 2- (2-chlorophenyl) ethoxycarbonyl group, 2- (3-chlorophenyl) group ethoxycarbonyl, 2- (4-chlorophenyl) ethoxycarbonyl group, 2-trifluoromethylbenzyloxycarbonyl group, 3-trifluoromethylbenzyloxycarbonyl group, 4-trifluoromethylbenzyloxycarbonyl group, 2- trifluoromethoxybenzyloxycarbonyl group, 3-trifluoromethoxybenzyloxycarbonyl group, 4-trifluoromethoxybenzyloxycarbonyl group, 2- (2-trifluoromethylphenyl) group ethoxycarbonyl, 2- (3-trifluoromethylphenyl) ethoxycarbonyl group, 2- (4-trifluoromethylphenyl) ethoxycarbonyl group, 2- (2-trifluoromethoxyphenyl) ethoxycarbonyl group, 2- (3-trifluoromethoxyphenyl) ethoxycarbonyl group, 2- (4-trifluoromethoxyphenyl) group ethoxycarbonyl, 3- (2-trifluoromethylphenyl) propoxycarbonyl group, 3- (3-trifluoromethylphenyl) propoxycarbonyl group, 3- (4-trifluoromethylphenyl) propoxycarbonyl group, 3- (2-trifluoromethylphenyl) propoxycarboxylic group bonyl, 3- (3-trifluoromethoxyphenyl) propoxycarbonyl group, 3- (4-trifluoromethoxyphenyl) propoxycarbonyl group, 4- (3-trifluoromethylphenyl) butoxycarbonyl group, 5- (4-trifluoromethylphenyl) pentoxycarbonyl group, 4- (4-trifluoromethoxyphenyl) group pentoxycarbonyl, 6- (3-trifluoromethylphenylhexyloxycarbonyl, 6- (4-trifluoromethylphenyl) hexyloxycarbonyl group, 6- (4-trifluoromethoxyphenyl) hexyloxycarbonyl group or the like. An amino group which may have a group selected from the group consisting of a Cl-Cβ alkanoyl group and a Cl-Cß alkyl group as a substituent includes an amino group which may have 1 or 2 groups selected from the group consisting of C1-C6 alkanoyl group and a C1-C6 alkyl group as a substituent, for example, an amino group, methylamino group, ethylamino group, n-propylamino group, isopropylamino group, n-butylamino group, tert-butylamino group, n-pentylamino group, n-hexylamino group, dimethylamino group, diethylamino group, di -n-propylamino, di-n-butylamino group, di-n-pentylamino group, di-n-hexylamino group, N-methyl-N-ethylamino group, N-ethyl-Nn-propylamino group, N-methyl-Nn group -butylamino, N-methyl-N-hexylamino group, N-methyl-N-acetylamino group, acetylamino group, formylamino group, n-propionylamino group, n-butyrylamino group, isobutyrylamino group, n-pentanoylamino group, n-hexanoylamino group, N-ethyl-N-acetylamino group or the like.

A 1, 2, 3, 4-tetrahydroquinolyl group (wherein, in the 1, 2, 3, 4-tetrahydroquinoline ring, at least one oxo group can be substituted as a substituent) includes a group 1, 2, 3, 4 -tetrahydroquinolyl (wherein, in the 1,2,3,4-tetrahydroquinoline ring, 1 or 2 oxo groups can be substituted as a substituent), for example, a 1,2,3,4-tetrahydro-1-quinolyl group , group 1, 2, 3, 4-tetrahydro-2-quinolyl, group 1, 2, 3, 4-tetrahydro-3-quinolyl, 1,2,3,4-tetrahydro-4-quinolyl group, group 1, 2 , 3, 4-tetrahydro-5-quinolyl, group 1, 2, 3, 4-tetrahydro-6-quinolyl, 1,2,3,4-tetrahydro-7-quinolyl group, group 1, 2, 3, 4- tetrahydro-8-quinolyl, 2-oxo-l, 2, 3, 4-tetrahydro-l-quinolyl group, 4-oxo- 1, 2, 3, 4-tetrahydro-l-quinolyl group, 2, 4-dioxo group -l, 2, 3, 4-tetrahydro-1-quinolyl, 2-oxo-l, 2, 3, 4-tetrahydro-6-quinolyl group, 2-oxo-l, 2, 3, 4-tetrahydro-4 group -quinolyl, 2-oxo-l, 2, 3, 4-tetrahydro-7-quinolyl group, 2-oxo-l, 2, 3, 4-tetrahydro-8-quinolyl group, 2-oxo-l, 2, 3, 4-tetrahydro-5-quinolyl group, 2-oxo-l, 2, 3, 4-tetrahydro-3-quinolyl group or the like. An alkylsulfonyl Cl-Cß group is a group consisting of an alkyl group containing 1 to 6 carbon atoms and a sulfonyl group, examples of which include a methanesulfonyl group, ethanesulfonyl group, n-propanesulfonyl group and n-butanesulfonyl group, group n-pentanesulfonyl, n-hexansulfonyl group or the like. A C3-C8 cycloalkyl group is a cyclic alkyl group of three members, four members, five members, six members, seven members or eight members containing 3 to 8 carbon atoms, examples of which include a cyclopropyl group, cyclobutyl group, cyclopentyl group, cyclohexyl group, cycloheptyl group, cyclooctyl group, 3, 4-dimethylcyclopentyl group, 3, 3-dimethylcyclohexyl group or the like. An alkylthio Cl-Cß group is a straight or branched alkylthio group containing 1 to 6 carbon atoms, examples of which include a methylthio group, ethylthio group, n-propylthio group, isopropylthio group, n-butylthio group, isobutylthio group, tert-butylthio group, sec-butylthio group, n-pentthylthio group, neopentylthio group, n-hexylthio group, isohexylthio group, 3-methylpentylthio group or the like. A phenylsulfonyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen, a substituted or unsubstituted Cl-Cβ alkoxy group halogen can be substituted) is an unsubstituted phenylsulfonyl group or having 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, an alkoxy group Cl-Cβ substituted or unsubstituted with halogen as defined above, examples of which include a phenylsulfonyl group, 2-fluorophenylsulfonyl group, 3-fluorophenylsulfonyl group, 4-fluorophenylsulfonyl group, 2-chlorophenylsulfonyl group, 3-chlorophenylsulfonyl group, group 4 -chlorophenylsulphonyl, 2-bromophenylsulphonyl group, 3-bromophenylsulphonyl group, 4-bromophenylsulphonyl group, 2-iodophenylsulphonyl group, 3-iodophenylsulphonyl group, group 4-Iodophenylsulfonyl, group 2, 3-difluorophenylsulfonyl, group 3, 4-difluorophenylsulfonyl, group 3, 5-difluorophenylsulfonyl, group 2, 4-difluorophenylsulfonyl, group 2, ß-difluorophenylsulfonyl, group 2, 3-dichlorophenylsulfonyl, group 3, 4 -dichlorophenylsulfonyl, group 3, 5-dichlorophenylsulfonyl, group 2, 4-dichlorophenylsulfonyl, group 2, ß-dichlorophenylsulfonyl, group 3, 4, 5-trifluorophenylsulfonyl, group 3, 4, 5-trichlorophenylsulphonyl, 2,4, 6-trifluorophenylsulfonyl group , 2,4-trichlorophenylsulfonyl group, 2-fluoro-4-bromophenylsulphonyl group, 4-chloro-3-fluorophenylsulphonyl group, 2, 3, 4-trichlorophenylsulfonyl group, 3,4,5-trifluorophenylsulfonyl group, group 2,3 , 4,5, 6-pentafluorophenylsulfonyl, 2, 4, 6-trimethylphenylsulfonyl group, 4-n-butylphenylsulfonyl group, 2, 4-dimethylphenylsulfonyl group, 2,3-dimethylphenylsulfonyl group, 2, 6-dimethylphenylsulfonyl group, 3,5-dimethylphenylsulfonyl group, 2,5-dimethylphenylsulfonyl group, 3, 5-ditrifluoromethylphenylsulfonyl group, 4-n-butoxyphenylsulfonyl group, 2, 4-dimethoxyphenylsulfonyl group, 2,3-dimethoxyphenylsulfonyl group, 2, 6-dimethoxyphenylsulfonyl group, 3,5-dimethoxyphenylsulfonyl group, 2, 5-dimethoxyphenylsulfonyl group, 2,4,6-trimethoxyphenylsulfonyl group , group 3, 5-ditrifluoromethoxyphenylsulfonyl, 3-chloro-4-methoxyphenylsulfonyl group, 2-chloro-4-trifluoromethoxyphenylsulfonyl group, 3-methyl-4-fluorophenylsulfonyl group, 4-bromo-3-trifluoromethylphenylsulfonyl group, 2-methylphenylsulfonyl group, group 3-Methylphenylsulfonyl, 4-methylphenylsulfonyl group, 2-methyl-3-chlorophenylsulfonyl group, 3-methyl-4-chlorophenylsulfonyl group, 2-chloro-4-methylphenylsulfonyl group, 2-methyl-3-fluorophenylsulfonyl group, 2-trifluoromethylphenylsulfonyl group , 3-trifluoromethyl group ilsulfonyl, 4-trifluoromethylphenylsulfonyl group, 2-pentafluoroethylphenylsulfonyl group, 3-pentafluoroethylphenylsulfonyl group, 4-pentafluoroethylphenylsulfonyl group, 2-isopropylphenylsulfonyl group, 3-isopropylphenylsulfonyl group, 4-isopropylphenylsulfonyl group, 2-tert-butylphenylsulfonyl group, 3-tert-group -but ilf enylsulfonyl, 4-tert-butylphenylsulfonyl group, 2-sec-butylphenylsulfonyl group, 3-sec-butylf-enylsulfonyl group, 4-sec-butylphenylsulfonyl group, 2-n-heptaf group, luoropropylfhenylsulfonyl, group 3-n -heptafluoropropylphenylsulfonyl, 4-n-heptaf luoropropylfinsyl sulfonyl group, 4-n-pentylphenylsulfonyl group, 4-n-hexylphenylsulfonyl group, 2-methoxyphenylsulfonyl group, 3-methoxyphenylsulfonyl group, 4-methoxyphenylsulfonyl group, 3-chloro-2 group -methoxyphenylsulfonyl, 2-fluoro-3-methoxyphenylsulfonyl group, 2-fluoro-4-methoxyphenylsulfonyl group, group 2, 6-dimethoxyphenylsulfonyl, group 2, 3, 4-trifluorofennylsulfonyl, group 2, 4 , 6-trifluorof e nilsulf onyl, 2-trifluoromethoxyphenylsulfonyl group, 3-trif luor omet oxy phenyl sulfonyl group, 4-trifluoromethoxyfrylsulphonyl group, 3-fluoro-2-trifluoromethoxyfrylsulfonyl group, 2-fluoro-3-trifluoromethoxyfrylsulfonyl group, 3-fluoro-4-trifluoromethoxy-enylsulfonyl group, 3-chloro-2-trifluoromethoxyphenylsulfonyl group, 2-chloro-3-trifluoromethoxy-phenylsulfonyl group, 3-chloro-4-trifluor omet oxy-phenyl group sulfonyl, group 2-pentaf luor oethoxy-enlylsulfonyl, group 3-pentaf luor oethoxy-enlylsulfonyl, group 4-pentaf luor oethoxy-enlylsulfonyl, 3-chloro-2-pentafluoroethoxyphenylsulfonyl group, 2-chloro-3-pentafluoroethoxyphenylsulfonyl group , 3-Chloro-4-pentafluoroethoxyphenylsulfonyl group, 2-isopropoxyphenylsulfonyl group, 3-isopropoxyphenylsulfonyl group, 4-isopropoxyphenylsulfonyl group, 2-tert-butoxyphenylsulfonyl group, 3-tert-butoxyphenylsulfonyl group, 4-tert-butoxyphenylsulfonyl group, 2-sec group -butoxyphenylsulfonyl, 3-sec-butoxyphenylsulfo group nyl, 4-sec-butoxyphenylsulfonyl group, 2-n-heptafluoropropoxyphenylsulfonyl group, 3-n-heptafluoropropoxyphenylsulfonyl group, 4-n-heptafluoropropoxyphenylsulfonyl group, 4-n-pentoxyphenylsulfonyl group, 4-n-hexyloxyphenylsulfonyl group or the like. A C 1 -C 6 alkoxy group substituted with amino which may have C 1 -C 6 alkyl groups as substituents includes an amino-C 1 -C 6 alkoxy group which may have 1 or 2 C 1 -C 6 alkyl groups as a substituent, eg, a group aminomethoxy, 2-aminoethoxy group, 1-aminoethoxy group, 3-aminopropoxy group, 4-aminobutoxy group, 5-aminopentyloxy group, 6-aminohexyloxy group, 2-methyl-3-aminopropoxy group, group 1, l-dimethyl-2- aminoethoxy, ethylaminoethoxy group, 1- (propylamino) ethoxy group, 2- (methylamino) ethoxy group, 3- (isopropylamino) propoxy group, 4- (n-butylamino) butoxy group, 5- (n-pentylamino) pentyloxy group, group 6- (n-hexylamino) hexyloxy, dimethylaminomethoxy group, 3-dimethylaminopropoxy group, (N-ethyl-N-propylamino) methoxy group, 2- (N-methyl-N-hexylamino) ethoxy group or the like. A phenyl group [where, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, a C1-Cβ alkoxy group substituted or unsubstituted with halogen, an amino group the which may have substituents selected from the group consisting of a Cl-Cβ alkanoyl group and a Cl-Cß alkyl group as a substituent, a Cl-Cβ alkoxycarbonyl group, a phenyl group, a phenoxy group (wherein, on the phenyl ring, less one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), an aminosulfonyl group, a group 1 , 2, 3, 4-tetrahydroquinolyl (wherein, in ring 1, 2, 3, 4-tetrahydroquinoline, at least one oxo group can be substituted as a substituent), an alkylsulfonyl group Cl-Cß, C3-C8 cycloalkyl group , a nitro group, a gr upo cyano, an alkylthio Cl-Cß group, a phenylsulfonyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cß alkyl group substituted with hydroxyl group and a group: (wherein, Wi represents an alkylene group Cl up to Cβ, and R11 and R12 are identical or different and each represents a C1-C6 alkoxy group) can be substituted as a substituent] includes a phenyl group which can be substituted in the positions 2 to 6 of the phenyl ring by 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen, a substituted or unsubstituted Cl-Cβ alkoxy group with halogen, an amino group which may have 1 or 2 substituents selected from the group consisting of a Cl-Cβ alkanoyl group and a Cl-Cβ alkyl group as a substituent, a Cl-Cβ alkoxycarbonyl group, a phenyl group, a group phenoxy (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a or substituted or unsubstituted haloalkyl Cl-Cβ can be substituted), an aminosulfonyl group, a 1,2,3,4-tetrahydroquinolyl group (wherein, in the 1, 2, 3, 4-tetrahydroquinoline ring, 1 to 2 oxo groups can be substituted as a substituent), an alkylsulfonyl Cl-Cß group, a C3-C8 cycloalkyl group, a nitro group, a cyano group, an alkylthio Cl-Cß group, a phenylsulfonyl group (wherein, in the phenyl ring , 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) , a Cl-Cß alkyl group substituted with hydroxyl group and a group: (wherein, Wi represents an alkylene group Cl up to Cβ, and R 11 and R 12 are identical or different and each represents a Cl-Cβ alkoxy group) as described above. A straight or branched C1-Cß alkyl group substituted with a hydroxyl group having 1 to 3 hydroxyl groups, for example, a hydroxymethyl group, 2-hydroxyethyl group, 1-hydroxyethyl group, 3-hydroxypropyl group, 2,3-dihydroxypropyl group , 4-hydroxybutyl group, 3,4-dihydroxybutyl group, 1-l-dimethyl-2-hydroxyethyl group, 5-hydroxypentyl group, 6-hydroxyhexyl group, 2-methyl-3-hydroxypropyl group, group 2, 3, 4- trihydroxybutyl or the like.

A C1-C10 alkoxy group substituted or unsubstituted with halogen includes, in addition to a C1-C10 alkoxy group substituted or unsubstituted with halogen as described above, a C1-C10 alkoxy group substituted by 1 to 7 C1-C10 alkoxy groups and halogen atoms, for example, a heptyloxy group, an octyloxy group, a nonyloxy group, a decyloxy group, a 7-fluoroheptyloxy group, a 1, 1,6-trifluoroheptyloxy group, a 7,7,7,6,6,5,5-heptafluoroheptyloxy group , 8-chloroctyloxy group, 8,8-dibromooctyloxy group, 6, 7, 8-trifluorooctyloxy group, 8, 8, 8, 7, 7, 6, 6-heptafluorooctyloxy group, 8,8,8,7,7- pentachloroctyloxy, 9-iodononyloxy group, 9,9-dibromononyloxy group, group 9, 9, 9, 8, 8-pentachlorononyloxy, group 9, 9, 9, 8, 8, 7, 7-heptafluorononyloxy, group 10-chlorodedecyloxy, group 10, 10-dibromodecyloxy, group 10,10,10,9-tetrachlorodecyloxy, group 10,10,10,9,9,9,8,8-heptafluorodecyloxy or the like. A C1-C3 alkyl phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a C1-C4 alkylenedioxy group, a phenyl group, a halogen atom, a C1-C3 alkyl group substituted or not substituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted as a substituent) is a Cl-Cβ alkyl group substituted or unsubstituted phenyl ring constituting the alkyl group by 1 to 5, preferably 1 to 3 substituents (preferably 1 or 2 substituents if the substituent is a C1-C4 alkylenedioxy group) selected from the group consisting of a C1-C4 alkylenedioxy group, a phenyl group, a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted or unsubstituted Cl-Cβ alkoxy group with halogen, examples of which include a benzyl group, 1-phenethyl group, 2-phenethyl group, 3-phenylpropyl group, 2-phenylpropyl group, 4-phenylbutyl group, 5-phenylpentyl group, 4-phenylpentyl group, 6-phenylhexyl group, 2-3-methylenedioxybenzyl group, 3, 4-methylenedioxybenzyl group 3-phenylbenzyl, 2-phenylbenzyl group, 4-phenylbenzyl group, 3-diphenylbenzyl group, 2, 4,6-triphenylbenzyl group, 2-fluorobenzyl group, 3-fluorobenzyl group, 4-fluorobenzyl group, 2-chlorobenzyl group, 3-chlorobenzyl group, 4-chlorobenzyl group, 2-bromobenzyl group, 3-bromobenzyl group, 4-bromobenzyl group, 2-iodobenzyl group, 3-iodobenzyl group, 4-iodobenzyl group, 2-difluorobenzyl group 3 group, 4-difluorobenzyl, group 3, 5-difluorobenzyl, group 2, 4-difluorobenzyl, 2,6-difluorobenzyl group, group 2, 3-dic lorobenzyl, 3,4-dichlorobenzyl group, 3-dichlorobenzyl group, 2,4-dichlorobenzyl group, 2-dichlorobenzyl group, 2-fluoro-4-bromobenzyl group, 4-chloro-3-fluorobenzyl group 2 , 3,4-trichlorobenzyl, group 3, 4, 5-trifluorobenzyl, 2,4,6-trichlorobenzyl group, 4-ethylbenzyl group, 4-sec-butylbenzyl group, 4-isopropylbenzyl group, 4-n-butylbenzyl group, group 4-methylbenzyl, 2-methylbenzyl group, 3-methylbenzyl group, 2, 4-dimethylbenzyl group, 2,3-dimethylbenzyl group, 2-dimethylbenzyl group, 3,5-dimethylbenzyl group, 2-dimethylbenzyl group, group 2,4,6-trimethylbenzyl, group 3, 5-ditrifluoromethylbenzyl, group 2, 3, 4, 5, 6-pentafluorobenzyl, 4-isopropoxybenzyl group, 4-n-butoxybenzyl group, 4-tert-butoxybenzyl group, group 4 methoxybenzyl, 2-methoxybenzyl group, 3-methoxybenzyl group, 2, 4-dimethoxybenzyl group 2-3-dimethoxybenzyl group 2, 6-dimethoxybenzyl group 3,5-dimethoxybenzyl group 2,5-dimethoxybenzyl group 2 4, 6-trimethoxybenzyl, gru po 3,5-ditrifluoromethoxybenzyl, 2-isopropoxybenzyl group, 3-chloro-4-methoxybenzyl group, 2-chloro-4-trifluoromethoxybenzyl group, 3-methyl-4-fluorobenzyl group, 4-bromo-3-trifluoromethylbenzyl group 2 -trifluoromethylbenzyl, 3-trifluoromethylbenzyl group, 4-trifluoromethylbenzyl group, 2-pentafluoroethylbenzyl group, 3-pentafluoroethylbenzyl group, 4-pentafluoroethylbenzyl group, 2-trifluoromethoxybenzyl group, 3-trifluoromethoxybenzyl group, 4-trifluoromethoxybenzyl group, 2-pentafluoroethoxybenzyl group 3 -pentafluoroethoxybenzyl, 4-pentafluoroethoxybenzyl group, 2- (2-trifluoromethylphenyl) ethyl group, 2- (3-trifluoromethylphenyl) ethyl group, 2- (4-trifluoromethylphenyl) ethyl group, 2- (2-trifluoromethoxyphenyl) ethyl group, group 1 - (3-trifluoromethoxyphenyl) ethyl, 2- (4-trifluoromethoxyphenyl) ethyl group, 2- (2-pentafluoroethoxyphenyl) ethyl group, 2- (3-pentafluoroethoxyphenyl) ethyl group, 2- (4-pentafluoroethoxyphenyl) ethyl group, group 3 - (2-trifluoromethylphenyl) propyl, group or 3- (3-trifluoromethylphenyl) propyl, 3- (4-trifluoromethylphenyl) propyl group, 3- (2-trifluoromethoxyphenyl) ropyl group, 3- (3-trifluoromethoxyphenyl) propyl group, 3- (4-trifluoromethoxyphenyl) propyl group, 3- (3-pentafluoroethoxyphenyl) propyl group, 3- (4-pentafluoroethoxyphenyl) propyl group, 4- (3-pentafluoroethoxyphenyl) butyl group, 5- (4-trifluoromethylphenyl) pentyl group, 4- (4-trifluoromethylphenyl) pentyl group 4- (4-trifluoromethoxyphenylpentyl, 6- (3-trifluoromethylphenyl) hexyl group, 6- (4-trifluoromethylphenyl) hexyl group, 6- (4-trifluoromethoxyphenyl) hexyl group, 4- (4-chlorophenyl) butyl group or the like. A C1-C3 alkyl phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a C1-C4 alkylenedioxy group, a phenyl group (wherein, in the phenyl ring, at least one selected from the group which consists of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a group-N (R11A) R12A (wherein R11A and R12A are identical or different, and each represents a hydrogen atom, C1-C6 alkyl group or phenyl group, and R11A and R12A can be linked to each other through or not through a nitrogen, oxygen or sulfur atom to form a saturated five- to seven-membered heterocyclic ring together with the nitrogen atom adjacent to this), a phenoxy group (wherein, in the phenyl ring, at least one selected of the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted by halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted by halogen can be substituted), a C 1 -C 6 alkoxy phenyl group, a group C1-C6 alkoxy substituted with amino group which may have C1-C6 alkyl groups as a substituent, a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C10 alkoxy group substituted or unsubstituted with Halogen can be subst as a substituent] includes, in addition to a C1-C4 alkyl phenyl group as described above (wherein, on the phenyl ring, at least one selected from the group consisting of a C1-C4 alkylenedioxy group, a phenyl group, a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted as a substituent), a Cl-Cβ phenyl alkyl group [wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents (preferably 1 or 2 substituents if the substituent is a C1-C4 alkylenedioxy group) selected from the group consisting of a C1-C4 alkylenedioxy group, a phenyl group as described above ( wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a straight or branched alkyl group substituted or unsubstituted with halogen containing ne 1 to 6 carbon atoms, a straight or branched alkoxy group substituted or unsubstituted with halogen containing 1 to 6 carbon atoms can be substituted), a group -N (R11A) R12A (wherein Rlla and R12A are identical or different, and each represents a hydrogen atom, a C1-C6 alkyl group as described above or a phenyl group, and R11A and R12A as described later can be linked to each other through or not through a carbon atom. nitrogen, oxygen or sulfur to form a saturated five- to seven-membered heterocyclic ring together with the nitrogen atom adjacent to it), a phenoxy group as described above (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a straight or branched alkyl group substituted or unsubstituted with halogen containing 1 to 6 carbon atoms, a straight or branched alkoxy group substituted or not substituted with halogen containing 1 to 6 carbon atoms can be substituted), a C 1 -C 6 alkoxy phenyl group as described above, a C 1 -C 6 alkoxy group substituted with amino group which can have a Cl-Cß alkyl group as a substituent as described above, a halogen atom as described above, a C1-C6 alkyl group substituted or unsubstituted with halogen as described above and a halogen atom as described above, a C1-C10 alkoxy group substituted or not substituted with halogen as described above may be substituted], for example, a 4- (4-trifluoromethylphenyl) benzyl group, 4- (4-trifluoromethoxyphenyl) benzyl group, 4- (4-chlorophenyl) benzyl group 4- ( 4-trifluoromethylphenoxy) benzyl, 4- (4-trifluoromethoxyphenoxy) benzyl group, 4- (4-chlorophenoxy) benzyl group, 4-phenoxybenzyl group, 3-phenoxybenzyl group, 2-phenoxybenzyl group, 2-4-diphenoxybenzyl group 2 , 4,6-trifenoxibenzyl, 4-benzyloxy group ibencil, 3-benzyloxybenzyl group, 2-benzyloxybenzyl group, 3,4-dibenzyloxybenzyl group, group 3, 4, 5-tribenzyloxybenzyl, 4-octyloxybenzyl group, 3-nonyloxybenzyl group, 2-decyloxybenzyl group, 4-heptyloxybenzyl group, 2, 4-dioctyloxybenzyl group, 3, 4,6-trioctyloxybenzyl group 4 ( 8, 8, 8-trifluorooctyloxy) benzyl, 4-dimethylaminobenzyl group, 4-difylaminobenzyl group, 4- (3-dimethylaminopropoxy) benzyl group, 4-di-n-butylaminobenzyl group, group 3- (N-methyl-N -ethylamino) benzyl, group 2- (N-methyl-N-phenylamino) benzyl, group 2, 4, 6-methylaminobenzyl, group 3- (3-dimethylaminopropoxy) benzyl, group 2, 4-di-n-butylaminobenzyl, group 4- (2-methylaminoethoxy) benzyl, 2- (4-methylaminobutoxy) benzyl group, 4- (2-dimethylaminoethoxy) benzyl group 2, 3-diethylaminomethoxybenzyl, 2, 4,6-tri (2-dimethylaminoethoxy) benzyl group , 2-f-enoxy-3-f-enylbenzyl group, 4-octyloxy-3-trifluoromethoxybenzyl group, 4-benzyloxy-2-dimethylaminobenzyl group, 4- (1-pyrrolidinyl) benzyl group, 4- (1-piperidyl) benzyl group or Similar . A C 1 -C 6 alkyl benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted Cl-Cβ alkoxy group or unsubstituted with halogen can be substituted] includes a Cl-Cß benzofuryl alkyl group [wherein, in the benzofuran ring, 1 to 3 substituents selected from the group consisting of a halogen atom as described above, an alkyl group Cl- Cβ substituted or unsubstituted with halogen as described above and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen as described above can be substituted], for example, a group (2-, 3-, 4-, 5- , 6- or 7-) benzofurylmethyl, group 1- (2-benzofuryl) ethyl, group 2- (3-benzofuryl) ethyl, group 3- (4-benzofuryl) propyl, group 2- (5-benzofuryl) propyl, group 2- (6-benzofuryl) propyl, 4- (7-benzofuryl) butyl group, 5- (2-benzofuryl) group pentyl, 4- (3-benzofuryl) pentyl group, 6- (4-benzofuryl) hexyl group, 2-methyl-3- (5-benzofuryl) propyl group, group 1, l-dimethyl-2- (6-benzofuryl) ethyl, (5-chloro-2-benzofuryl) methyl group, 2- (5-trifluoromethoxybenzofuryl) methyl group, 2- (5-trifluoromethylbenzofuryl) methyl group, (6-trifluoromethylbenzofuryl) methyl group, 2- (5-) group methylbenzofuryl) methyl, 2- (5-methoxybenzofuryl) methyl group, (5, β-dibromo-2-benzofuryl) methyl group, (3,5,6-trifluoro-2-benzofuryl) methyl group 2- ( 5,6-dimethylbenzofuryl) methyl, 2- (5,7-dimethoxybenzofuryl) methyl group, 2- (5,6,7-trimethyl-ilbenzofuryl) methyl group, 2- (3,5,6-trimethoxybenzofuryl) methyl group, 2- (5-trifluoromethyl-6-chlorobenzofuryl) methyl group, 2- (5-trifluoromethoxy-6-methoxybenzofuryl) methyl group or the like. A phenylsulfonyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted] is an unsubstituted phenylsulfonyl group or having 1 to 5, preferably 1 to 3 substituents (preferably 1 or 2 substituents if the substituent is a C 1 -C 4 alkylenedioxy group) selected from the group consisting of a halogen atom , a C1-C6 alkyl group substituted or not substituted by halogen, a C1-C6 alkoxy group substituted or unsubstituted by halogen and a C1-C4 alkylenedioxy group as defined above, for example, a phenylsulfonyl group, 2-fluorophenylsulfonyl group, 3-fluorophenylsulphonyl group, 4-fluorophenylsulphonyl group, 2-chlorophenylsulphonyl group, 3-chlorophenylsulphonyl group, 4-chlorophenylsulphonyl group, 2-bromophenylsulphonyl group, 3-bromophenyl group sulfonyl, 4-bromophenylsulphonyl group, 2-iodophenylsulfonyl group, 3-iodophenylsulfonyl group, 4-iodophenylsulfonyl group, 2, 3-difluorophenylsulfonyl group, 3, 4-difluorophenylsulfonyl group, 3, 5-difluorophenylsulfonyl group, 2,4-difluorophenylsulfonyl group, 2, 6-difluorophenylsulfonyl group, 2-dichlorophenylsulfonyl group, 3,4-dichlorophenylsulfonyl group, 3-dichlorophenylsulfonyl group, 2, 4-dichlorophenylsulfonyl group, 2, 6-dichlorophenylsulfonyl group, group 3, 4, 5-trifluorophenylsulfonyl, 3,4,5-trichlorophenylsulfonyl group, 2, 4,6-trifluorophenylsulfonyl group 2, 4,6-trichlorophenylsulfonyl, 2-fluoro-4-bromophenylsulphonyl group, 4-chloro group 3-fluorophenylsulfonyl, group 2, 3, 4-trichlorophenylsulfonyl, 3,4,5-trifluorophenylsulfonyl group, 2,3,4,5,6-pentafluorophenylsulfonyl group, 2, 4,6-trimethylphenylsulfonyl group, 4-n-butylphenylsulfonyl group , 2,4-dimethylphenylsulfonyl group, 2,3-dimethylphenylsulfonyl group, 2,6-dimethylphenylsulfonyl group, 3, 5-dimethylphenylsulfonyl group, 2, 5-dimethylphenylsulfonyl group, 3,5-ditrifluoromethylphenylsulfonyl group, 4-n-butoxyphenylsulfonyl group, Group 2, 4-dimethoxyphenylsulfonyl, group 2, 3-dimethoxyphenylsulfonyl, group 2, 6-dimethoxyphenylsulph onyl, group 3, 5-dimethoxyphenylsulfonyl, 2,5-dimethoxyphenylsulfonyl group, 2, 4,6-trimethoxyphenylsulfonyl group, 3-ditrifluoromethoxyphenylsulfonyl group, 3-chloro-4-methoxyphenylsulfonyl group, 2-chloro-4-trifluoromethoxyphenylsulfonyl group, 3-methyl-4-fluorophenylsulfonyl group, 4-bromo-3-trifluoromethylphenylsulfonyl group, 2-methylphenylsulfonyl group, 3-methylphenylsulfonyl group, 4-methylphenylsulfonyl group, 2-methyl-3-chlorophenylsulfonyl group, 3-methyl-4-chlorophenylsulfonyl group , 2-chloro-4-methylphenylsulfonyl group, 2-methyl-3-fluorophenylsulfonyl group, 2-trifluoromethylphenylsulfonyl group, 3-trifluoromethylphenylsulfonyl group, 4-trifluoromethylphenylsulfonyl group, 2-pentafluoroethylphenylsulfonyl group, 3-pentafluoroethylphenylsulfonyl group, 4-pentafluoroethylphenylsulfonyl group, group 2- isopropylphenylsulfonyl, 3-isopropylphenylsulfonyl group, 4-isopropylphenylsulfonyl group, 2-tert-butylphenylsulfonyl group, 3-tert-butylphenylsulfonyl group, 4-tert-butylphenylsulfonyl group, upo 2-sec-butylphenylsulfonyl, 3-sec-butylphenylsulfonyl group, 4-sec-butylphenylsulfonyl group, 2-n-heptafluoropropylphenylsulfonyl group, 3-n-heptafluoropropylphenylsulfonyl group, 4-n-heptafluoropropylphenylsulfonyl group, 4-n-pentylphenylsulfonyl group, group 4-n-hexylphenylsulfonyl, 2-methoxyphenylsulfonyl group, 3-methoxyphenylsulfonyl group, 4-methoxyphenylsulfonyl group, 3-chloro-2-methoxyphenylsulfonyl group, 2-fluoro-3-methoxyphenylsulfonyl group, 2-fluoro-4-methoxyphenylsulfonyl group, group 2 , 6-dimethoxyphenylsulfonyl, 2,3-trifluorophenylsulfonyl group, 2,4,6-trifluorophenylsulfonyl group, 2-trifluoromethoxyphenylsulfonyl group, 3-trifluoromethoxyphenylsulfonyl group, 4-trifluoromethoxyphenylsulfonyl group, 3-fluoro-2-trifluoromethoxyphenylsulfonyl group, group 2 fluoro-3-trifluoromethoxyphenylsulfonyl, 3-fluoro-4-trifluoromethoxyphenylsulfonyl group, 3-chloro-2-trifluoromethoxyphenylsulfonyl group, 2-chloro-3-trifluoromethoxyphenylsulfonyl group, 3-chloro-4-trifluoromethoxyphenylsulfonyl group onyl, 2- pentafluoroethoxyphenylsulfonyl group, 3-pentafluoroethoxyphenylsulfonyl group, 4-pentafluoroethoxyphenylsulfonyl group, 3-chloro-2-pentafluoroethoxyphenylsulfonyl group, 2-chloro-3-pentafluoroethoxyphenylsulfonyl group, 3-chloro-4-pentafluoroethoxyphenylsulfonyl group, group 2 isopropoxyphenylsulfonyl, 3-isopropoxyphenylsulfonyl group, 4-isopropoxyphenylsulfonyl group, 2-tert-butoxyphenylsulfonyl group, 3-tert-butoxyphenylsulfonyl group, 4-tert-butoxyphenylsulfonyl group, 2-sec-butoxyphenylsulfonyl group, 3-sec-butoxyphenylsulfonyl group, group 4 sec-butoxyphenylsulfonyl, 2-n-heptafluoropropoxyphenylsulfonyl group, 3-n-heptafluoropropoxyphenylsulfonyl group, 4-n-heptafluoropropoxyphenylsulfonyl group, 4-n-pentoxyphenylsulfonyl group, 4-n-hexyloxyphenylsulfonyl group, 2, 3-methylenedioxyphenylsulfonyl group, group 3,4 -methylenedioxyphenylsulfonyl or the like. A phenoxycarbonyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted] includes a phenoxycarbonyl group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), for example, a phenoxycarbonyl group, fluorofenoxicarbonilo-2, 3- fluorofenoxicarbonilo group, 2,3,4,5,6-group pentafluorofenoxicarbonilo group, 4-fluorofenoxicarbonilo group, 2-chlorophenoxycarbonyl, 3-chlorophenoxycarbonyl group, 4-chlorophenoxycarbonyl group, 2,3-diclorofenoxicarbonilo, group group 3, 4-dichlorophenoxycarbonyl, group 3, 5-dichlorophenoxycarbonyl, 2-bromophenoxycarbonyl group, 3-bromophenoxycarbonyl group, 4-bromophenoxycarbonyl group, 2-methylphenoxycarbonyl group, group 3 -metilfenoxicarbonilo group, 4-methylphenoxycarbonyl group, 2-etilfenoxicarbonilo group, 3-etilfenoxicarbonilo group, 4-etilfenoxicarbonilo group, 4-n-propilfenoxicarbonilo group, 4-tert-butilfenoxicarbonilo group, 4-n-butilfenoxicarbonilo, group 2, 3-dimethylphenoxycarbonyl , 3,4,5-trimethylphenoxycarbonyl group, 4-n-pentylphenoxycarbonyl group, 4-n-hexylphenoxycarbonyl group, 2-fluoro-4-bromophenoxycarbonyl group, 4-chloro-3-fluorophenoxycarbonyl group, 2, 3, 4-trichlorophenoxycarbonyl group , 2,4,6-triclorofenoxicarbonilo group, 4-isopropilfenoxicarbonilo group, 4-n-butilfenoxicarbonilo group, 2,4-dimethylphenoxycarbonyl group, 2, 3-dimethylphenoxycarbonyl group, 2, ß-dimethylphenoxycarbonyl group, 3,5- dimethylphenoxycarbonyl, group 2, 5-dimethylphenoxycarbonyl, 2,6-dimetoxifenoxicarbonilo group 2, 4, 6-trimetilfenoxicarbonilo, 3,5- ditrifluorometilfenoxicarbonilo group, group 4-n-butoxifenoxicarbonilo, group 2, 4-dimetoxifenoxicarbonilo, group 2, 3-dimetoxifenoxicarbonilo, group , group or 3, 5-dimethoxyphenoxycarbonyl, 2,5-dimethoxyphenoxycarbonyl group, 3,5-ditrifluoromethoxy-phenoxycarbonyl group, 3-chloro-4-methoxyphenoxycarbonyl group, 2-chloro-4-trifluoromethoxyphenoxycarbonyl group, 3-methyl-4-methyl group. fluorophenoxycarbonyl, 4-bromo-3-trifluoromethylphenoxycarbonyl group, 2-trifluoromethylphenoxycarbonyl group, 3-trifluoromethylphenoxycarbonyl group, 4-trifluoromethylphenoxycarbonyl group, 2-pentafluoroethylphenoxycarbonyl group, 3-pentafluoroethylphenoxycarbonyl group, 4-pentafluoroethylphenoxycarbonyl group, 2-methoxyphenoxycarbonyl group, group 3 -metoxifenoxicarbonilo group, 4-methoxyphenoxycarbonyl group, 2-etoxifenoxicarbonilo group, 3-etoxifenoxicarbonilo group, 4-etoxifenoxicarbonilo group, 4-n-propoxifenoxicarbonilo group, 4-tert-butoxifenoxicarbonilo group, 4-n-butoxifenoxicarbonilo, 2,3-dimetoxifenoxicarbonilo , group 3, 4, 5-trimethoxyphenoxycarbonyl, 4-n-pentoxyphenoxycarbonyl group, 4-n-hexyloxyphenoxycarbonyl group, 2-trifluoromethoxyphenoxycarbonyl group, group or 3-trifluoromethoxyphenoxycarbonyl, 4-trifluoromethoxyphenoxycarbonyl group, 2-pentafluoroethoxyphenoxycarbonyl group, 3-pentafluoroethoxyphenoxycarbonyl group, 4-pentafluoroethoxyphenoxycarbonyl group or the like. A Cl-Cß alkyl group substituted with Cl-Cβ alkoxy is a group consisting of a Cl-Cß alkyl group and a Cl-Cß alkoxy group, both as described above, examples of which include a methoxymethyl group, group 2 methoxyethyl group, 3-methoxypropyl group, 4-methoxybutyl group, 5-methoxypentyl group, 6-methoxyhexyl, ethoxymethyl group, 2-ethoxyethyl group, 3-ethoxypropyl group, 2-isopropoxyethyl group, tert-butoxymethyl, pentyloxymethyl group, hexyloxymethyl group , 2- (tert-butoxy) ethyl group, 3- (tert-butoxy) propyl group, 6- (tert-butoxy) hexyl group, 4- (tert-butoxy) butyl group or the like. A C2-C6 alkenyl group includes a vinyl group, 2-propenyl group, 3-butenyl group, 2-butenyl group, 4-pentenyl group, 3-pentenyl group, 5-hexenyl group, 4-hexenyl group, 3-hexenyl group or similar. A C 2 -C 6 alkanoyl group substituted with Cl-Cβ alkoxy is a group consisting of a Cl-Cß alkyl group and a C 2 -C β alkanoyl group, both as described above, examples of which include a 2-methoxyacetyl group, 2-32β group methoxypropionyl, 3-methoxypropionyl group, 4-methoxybutyl group, 5-methoxypentanoyl group, 6-methoxyhexanoyl group, 2-ethoxyacetyl group, 2-ethoxypropionyl group, 3-ethoxypropionyl group, 2-isopropoxypropionyl group, 2- (tert-butoxy) group acetyl, 2-pentyloxyacetyl group, 2-hexyloxyacetyl group, 2- (tert-butoxy) propionyl group, 3- (tert-butoxy) propionyl group, 6- (tert-butoxy) hexanoyl group, 4- (tert-butoxy) group butyl or similar. A Cl-Cß alkyl group substituted with C3-C8 cycloalkyl is a group consisting of a cyclic alkyl group containing 3 to 8 carbon atoms and an alkyl group containing 1 to 6 carbon atoms, eg, of which one group cyclopropylmethyl, 2-cyclopropylethyl group, 3-cyclopropylpropyl group, 4-cyclopropylbutyl group, 5-cyclopropylpentyl group, β-cyclopropylhexyl group, cyclobutylmethyl group, 2-cyclobutylethyl group, 3-cyclobutylpropyl group, 4-cyclobutylbutyl group, 5-cyclobutylpentyl group, 6-cyclobutylhexyl group, cyclopentylmethyl group, 2-cyclopentylethyl group, 3-cyclopentylpropyl group, 4-cyclopentylbutyl group, 5-cyclopentylpentyl group, 6-cyclopentylhexyl group, cyclohexylmethyl group, 2-cyclohexylethyl group, 3-cyclohexylpropyl group, group 4 cyclohexyl butyl, 5-cyclohexylpentyl group, 6-cyclohexylhexyl group, cycloheptylmethyl group, 2-cycloheptylethyl group, 3-cycloheptylpropyl group, 4-cycloheptylbutyl group, 5-cyclohep group tilpentyl, 6-cycloheptylhexyl group, cyclooctylmethyl group, 2-cyclooctylethyl group, 3-cyclooctylpropyl group, 4-cyclooctylbutyl group, 5-cyclooctylpentyl group, 6-cyclooctylhexyl group or the like. A C1-C6 alkyl pyridyl group includes a 2-pyridylmethyl group, 2- (3-pyridyl) ethyl group, l- (4-pyridyl) ethyl group, 3- (2-pyridyl) propyl group, 4- (3- group pyridyl) butyl, 5- (4-pyridyl) pentyl group, 6- (2-pyridyl) hexyl group, 2-methyl-3- (3-pyridyl) propyl group, group 1, l-dimethyl-2- (2- pyridyl) ethyl or the like. A C1-C6 imidazolyl alkyl group (wherein, in the imidazole ring, a phenyl group can be substituted) includes a C1-C6 alkyl imidazolyl group (wherein, in the imidazole ring, 1 to 2 phenyl groups can be substituted), for example, a 4-imidazolylmethyl group, 2- (4-imidazolyl) ethyl group, 3- (2-imidazolyl) propyl group, 4- (1-imidazolyl) butyl group, 5- (5-imidazolyl) pentyl group, group 6- (4-imidazolyl) hexyl, group 2, 5-diphenyl-1-imidazolylmethyl, 2-phenyl-4-imidazolylmethyl group, 2- (2-phenyl-4-imidazolyl) ethyl group, 3- (2-phenyl) group -4-imidazolyl) propyl, 4- (2-phenyl-5-imidazolyl) butyl group, 5- (2-phenyl-4-imidazolyl) pentyl group, 6- (2-phenyl-4-imidazolyl) hexyl group or the like . A 1, 2, 3, 4-tetrahydroquinolyl group (wherein, in the 1, 2, 3, 4-tetrahydroquinoline ring, at least one selected from the group consisting of an oxo group and a Cl-C6 alkyl group can be substituted as a substituent) includes a 1, 2, 3, 4-tetrahydroquinolyl group (wherein, in the 1,2,3,4-tetrahydroquinoline ring, 1 to 5 substituents selected from the group consisting of an oxo group and an alkyl group C1-C6 can be substituted), for example, a 1, 2, 3, 4-tetrahydro-l-quinolyl group, 1,2,3,4-tetrahydro-2-quinolyl group, group 1, 2, 3, 4 -tetrahydro-3-quinolyl, group 1, 2, 3, 4-tetrahydro-4-quinolyl, 1,2,3,4-tetrahydro-5-quinolyl group, group 1, 2, 3, 4-tetrahydro-6- quinolyl, group 1, 2, 3, 4-tetrahydro-7-quinolyl, 1,2,3,4-tetrahydro-8-quinolyl group, 2-oxo-l, 2, 3, 4-tetrahydro-l-quinolyl group , group 4-oxo-l, 2, 3, 4-tetrahydro-l-quinolyl, group 2, 4-dioxo-l, 2, 3, 4-tetrahydro-l-quinolyl, group 2-oxo-l, 2, 3, 4-tetrahydro-6-quinolyl, group 2-o xo-l, 2, 3, 4-tetrahydro-4-quinolyl, 2-oxo-l, 2, 3, 4-tetrahydro-7-quinolyl group, 2-oxo-l, 2, 3, 4-tetrahydro- group 8-quinolyl, 2-oxo-l, 2, 3, 4-tetrahydro-5-quinolyl group, 2-oxo-l, 2, 3, 4-tetrahydro-3-quinolyl group, 2-methyl-l, 2 group , 3, 4-tetrahydro-l-quinolyl, 4-ethyl-l group, 2, 3, 4-tetrahydro-l-quinolyl, 2,4-dimethyl-1,2,3,4-tetrahydro-l-quinolyl group, group 1, 5,6-trimethyl-l, 2, 3, 4 -tetrahydro-1-quinolyl, group 1, 4, 5, 6-tetramethyl-2-oxo-1,2,3,4-tetrahydro-l-quinolyl, 1-propyl-l, 2, 3, 4-tetrahydro group -6-quinolyl, 5-n-pentyl-l, 2, 3, 4-tetrahydro-4-quinolyl group, 6-n-hexyl-l, 2, 3, 4-tetrahydro-7-quinolyl group, group 7- tert-butyl-l, 2, 3, 4-tetrahydro-8-quinolyl, 8-n-pentyl-1, 2, 3, 4-tetrahydro-8-quinolyl group, ln-hexyl-2-oxo-1 group, 2, 3, 4-tetrahydro-8-quinolyl, l-methyl-2-oxo-l, 2, 3, 4-tetrahydro-5-quinolyl group, 3-ethyl-2-oxo-l, 2, 3 group, 4-tetrahydro-3-quinolyl or the like. An amino group which may have C 1 -C 6 alkyl groups as a substituent includes an amino group which may have 1 to 2 C 1 -C 6 alkyl groups as a substituent, for example, an amino group, methylamino group, ethylamino group, n-propylamino group , isopropylamino group, n-butylamino group, tert-butylamino group, n-pentylamino group, n-hexylamino group, dimethylamino group, diethylamino group, di-n-propylamino group, di-n-butylamino group, di-n-pentylamino group , di-n-hexylamino group, N-methyl-N-ethylamino group, N-ethyl-Nn-propylamino group, N-methyl-Nn-butylamino group, N-methyl-Nn-hexylamino group or the like. A C1-C6 alkyl group substituted with cyano includes a cyanomethyl group, 2-cyanoethyl group, 1-cyanoethyl group, 3-cyanopropyl group, 4-cyanobutyl group, 5-cyanopentyl group, 6-cyanohexyl group, 2-methyl group -cyanopropyl, group 1, l-dimethyl-2-cyanoethyl or the like. A C 1 -C 6 alkyl group substituted with furyl includes a 2-furylmethyl group, 3-furylmethyl group, 2- (2-furyl) ethyl group, 1- (3-furyl) ethyl group, 3- (2-furyl) propyl group , 3- (3-furyl) propyl group, 4- (2-furyl) butyl group, 4- (3-furyl) butyl group, 5- (2-furyl) pentyl group, 5- (3-furyl) pentyl group , 6- (2-furyl) hexyl group, 6- (3-furyl) hexyl group or the like. A C1-C6 alkyl group substituted with piperazinyl [wherein, in the piperazine ring, at least one phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group Cl-Cβ substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes a Cl alkyl group up to Cβ substituted with piperazinyl [wherein, in the piperazine ring, 1 to 3 phenyl groups as a substituent (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted by halogen can be substituted) can be substituted, eg, a 1-piperazinylmethyl group, 2- (2-piperazinyl) ethyl group, 1- (1-piperazinyl) ethyl group 3- ( 1-piperazinyl) propyl, 4- (1-piperazinyl) butyl group, 5- (2-piperazinyl) pentyl group, 6- (1-piperazinyl) hexyl group, 2- (4-phenyl-1-piperazinyl) ethyl group, 3- (4-phenyl-1-piperazinyl) propyl group, 4- (4-phenyl-1-piperazinyl) butyl group, 5- (4-phenyl-1-piperazinyl) pentyl group, 6- (4-phenyl) group 1-piperazinyl) hexyl, 2- (4- (2-fluorophenyl) -1-piperazinyl) ethyl group, 3- (4- (2-fluorophenyl) -1-piperazinyl) propyl group, group 4- (4- (2 , 3- difluorophenyl) -1-piperazinyl) butyl, 5- (4- (2-fluorophenyl) -1-piperazinyl) pentyl group, β- (4- (4-fluorophenyl) -1-piperazinyl) hexyl group, group 3 - (4- (3-fluorophenyl) -1-piperazinyl) propyl, 4- (4- (3-fluorophenyl) -1-piperazinyl) butyl group, 5- (4- (3-fluorophenyl) -1-piperazinyl) group pentyl, 3- (4- (4- fluorophenyl) -1-piperazinyl) propyl group, 4- (4- (fluorophenyl) group 1-piperazinyl) butyl, 5- (4- (4-fluorophenyl) -1-piperazinyl) pentyl group, 6- (4- (fluorophenyl) -1-piperazinyl) hexyl group, 2- (4- (2, 3) group -dichlorophenyl) -1-piperazinyl) ethyl, 3- (4- (2-chlorophenyl) -1-piperazinyl) propyl group, 4- (4- (2-chlorophenyl) -1-piperazinyl) butyl group 5- ( 4- (2,4-, 6-trichlorophenyl) -1-piperazinyl) pentyl, β- (4- (2-chlorophenyl) -1-piperazinyl) hexyl group, 2- (4- (3-chlorophenyl) -1- group piperazinyl) ethyl, 3- (4- (3-chlorophenyl) -1-piperazinyl) propyl group, 4- (4- (3-chlorophenyl) -1-piperazinyl) butyl group, group 5- (4- (2, 3 , 4, 5, 6-pentafluorophenyl) -1-piperazinyl) pentyl, ß- (4- (3-chloro-4-methylphenyl) -1-piperazinyl) hexyl group, 2- (4- (4-chlorophenyl) - 1-piperazinyl) ethyl, 3- (4- (4-chlorophenyl) -1-piperazinyl) propyl group, 4- (4- (4-chloro-3-methoxyphenyl) -1-piperazinyl) butyl group 5- ( 4- (4-chlorophenyl) -1-piperazinyl) pentyl, 6- (4- (4-chlorophenyl) -1- piperazinyl) hexyl group, 2- (4- (2-methylphenyl) -1- piper azinyl) methyl, 2- (4- (2,4-dimethylphenyl) -1- piperazinyl) methyl group, 2- (4- (2,4,6-trimethylphenyl) -1- piperazinyl) methyl group 2- ( 4- (2-trifluoromethylphenyl) -1- piperazinyl) ethyl, 3- (4- (3,5-ditrifluoromethylphenyl) -1-piperazinyl) propyl group, 4- (4- (2-trifluoromethylphenyl) -1-piperazinyl) group utilo, 5- (4- (2-trifluoromethylphenyl) -1-piperazinyl) pentyl group, 6- (4- (2-trifluoromethylphenyl) -1-piperazinyl) hexyl group, 3- (4- (3-trifluoromethylphenyl) - group 1-piperazinyl) propyl, 4- (4- (3-trifluoromethylphenyl) -1-piperazinyl) butyl group, 5- (4- (3-trifluoromethylphenyl) -1-piperazinyl) pentyl group, 3- (4- (4 -trifluoromethylphenyl) -1-piperazinyl) propyl, 4- (4- (4-trifluoromethylphenyl) -1-piperazinyl) butyl group, 5- (4- (4-trifluoromethylphenyl) -1-piperazinyl) pentyl group 6- ( 4- (4-trifluoromethylphenyl) -1-piperazinyl) hexyl, 2- (4- (3,5-ditrifluoromethoxyphenyl) -1-piperazinyl) ethyl group, 2- (4- (2-methoxyphenyl) -1-piperazinyl) group methyl, gr upo 2- (4- (2,4-dimethoxyphenyl) -1-piperazinyl) methyl, 2- (4- (2,4,6-trimethoxyphenyl) -1-piperazinyl) methyl group, group 3- (4- (2 -trifluoromethoxyphenyl) -1-piperazinyl) propyl, 4- (4- (2-trifluoromethoxyphenyl) -1-piperazinyl) butyl group, 5- (4- (2-trifluoromethoxyphenyl) -1-piperazinyl) pentyl group 6- ( 4- (2-trifluoromethoxyphenyl) -1-piperazinyl) hexyl, 3- (4- (3-trifluoromethoxyphenyl) -1-piperazinyl) propyl group, 4- (4- (3-trifluoromethoxyphenyl) -1- piperazinyl) butyl group, 5- (4- (3-trifluoromethoxyphenyl) -1-piperazinyl) pentyl group, 3- (4- (4-trifluoromethoxyphenyl) -1-piperazinyl) propyl group, 4- (4- (4-trifluoromethoxyphenyl) -1- group piperazinyl) butyl, 5- (4- (4-trifluoromethoxyphenyl) -1-piperazinyl) pentyl group, 6- (4- (4-trifluoromethoxyphenyl) -1-piperazinyl) hexyl group, 2,4-diphenyl-1-piperazinylmethyl group , group (2, 4, 5-triphenyl-1-piperadini) methyl or the like. R9 and R10, R11A and R12A, or R11B and R12B can be linked to each other directly or through a nitrogen, oxygen or sulfur atom, in order to form a 5-7 membered saturated heterocyclic ring group together with the atom of nitrogen adjacent to this. Examples of the 5-7 membered saturated heterocyclic ring group include a pyrrolidinyl group, a piperazyl group, a piperidyl group, a morpholino group, a thiomorpholino group, and a homopiperazinyl group. R9 and R10 can be linked to each other directly or through a nitrogen, oxygen or sulfur atom, in order to form a 1, 2, 3, 4-tetrahydroisoquinolyl group, an isoindolyl group, or the saturated heterocyclic ring of 7 members described above together with the nitrogen atom adjacent to this. In a group or ring, at least one selected from the group consisting of the following groups can be substituted: a halogen atom, a substituted or unsubstituted C 1 -C 6 alkyl group with halogen, a substituted or unsubstituted Cl-Cβ alkoxy group with halogen, a phenyl group [where, in the phenyl ring, at least one selected from the group consisting of a phenyl group, a halogen atom, a substituted or unsubstituted Cl-Cβ alkyl group with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen may be substituted], a benzoyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted by halogen, and a Cl-C alco alkoxy group C C substituted or unsubstituted with halogen can be substituted], a Cl-Cβ pyridyl alkyl group, a C3-C8 cycloalkyl group, a Cl-Cß phenyl alkyl group [wherein, on the phenyl ring, at least one selected from the group consists of a C1-C4 alkylenedioxy group, a halogen atom, a C1-C3 alkyl group substituted or unsubstituted with halogen, and a C1-C3 alkoxy group substituted or unsubstituted with halogen can be substituted], a C1-6 alkyl group Cß piperidyl, a group or piperidyl, a Cl-Cβ phenyl alkoxy group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen can be substituted], a phenoxy group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], an amino group wherein at least one selected from the group consisting of a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted by halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted by halogen can be substituted], a Cl-Cß alkyl group, and a group alqu ilo Cl-Cβ phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a substituted Cl-Cβ alkoxy group or unsubstituted with halogen can be substituted] can be substituted as a substituent, a benzoxazolyl group, a C2-C6 alkenyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), and a benzimidazolyl group. As such substituents, the groups 1 to 3 are selected from the following groups, each of which is described above or below, can be substituted: a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen, a Cl-Cβ alkoxy group substituted or unsubstituted by halogen, a phenyl group [wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a phenyl group, a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted by halogen, and a Cl-Cß alkoxy group substituted or unsubstituted by halogen can be substituted], a benzoyl group [wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] , a Cl-Cβ pyridyl alkyl group, a C3-C8 cycloalkyl group, a Cl-Cβ phenyl alkyl group [wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of C1-C4 alkylenedioxy group, a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted, and in a case where the substituent is a C1-C4 alkylenedioxy group, 1 or 2 groups are preferably substituted], a C1-C3 piperidyl alkyl group, a piperidyl group, a C1-C3 alkoxy phenyl group [wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], a phenoxy group [wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], an amino group wherein 1 or 2 groups selected from the group consisting of a phenyl group [wherein, on the phenyl ring, 1 to 5 groups, and preferable 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], an alkyl group Cl-Cβ, and a Cl-Cβ phenyl alkyl group [wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a substituted Cl-Cβ alkyl group or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted as a substituent, a benzoxazolyl group, a C2-C6 alkenyl group phenyl (wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a straight or branched alkyl group substituted or unsubstituted with halogen containing 1 to ß carbon atoms, and a group a straight or branched lcoxy substituted or unsubstituted with halogen containing 1 to 6 carbon atoms, can be substituted), and a benzimidazolyl group. R11B and R12B can be linked to each other directly or through a nitrogen, oxygen or sulfur atom, to thereby form the 5-7 membered saturated heterocyclic ring described above together with the nitrogen atom adjacent thereto. In a saturated 5-7 membered heterocyclic ring, at least one selected from the group consisting of a Cl-Cβ alkoxycarbonyl group and an amino group [wherein, in the amino group, at least one selected from the group consisting of a group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) and a Cl-Cß alkyl group can be substituted] can be substituted. An example of the substituent may be a group selected from the group consisting of a Cl-Cβ alkoxycarbonyl group and an amino group [wherein, in the amino group, 1 or 2 groups selected from the group consisting of a phenyl group (wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen, and a C1-Cß alkoxy group substituted or not substituted with halogen can be substituted) and a Cl-Cß alkyl group can be substituted], which is described above or below. Such substituents 1 to 3 can be substituted on the heterocyclic ring. The term phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a phenyl group, a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen, and an alkoxy Cl- group Cβ substituted or unsubstituted with halogen can be substituted] is used herein to mean an unsubstituted phenyl group or the phenyl group is defined as above, which comprises 1 to 5 substituents, and preferably 1 to 3 substituents selected from the group consisting of a phenyl group, a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or not substituted with halogen. Examples of the phenyl group may include a phenyl group, a 2-phenylphenyl group, a 3-phenylphenyl group, a 4-phenylphenyl group, a 2,3-diphenylphenyl group, a 2,4,6-triphenylphenyl group, a 2-group. fluorophenyl, 3-fluorophenyl group, a 4-fluorophenyl group, 2-chlorophenyl, a 3-chlorophenyl group, 4-chlorophenyl, 2-bromophenyl group, a 3-bromophenyl 4-bromophenyl group a-iodophenyl 3-iodophenyl 2 iodophenyl 4-difluorophenyl 2,4-group, a group, a group, a 2, 3-difluorophenyl, 3,4-difluorophenyl one group, a 3, 5-difluorophenyl group, a , a 2,6-difluorophenyl group, a 2,3-dichlorophenyl group, a 3,4-dichlorophenyl group, a 3,5-dichlorophenyl group, a 2,4-dichlorophenyl group, a 2,6-dichlorophenyl group, a group 3, 4, 5-trifluorophenyl, a 3, 4, 5-trichlorophenyl group, a 2,4,6-trifluorophenyl group, a 2, 4,6-trichlorophenyl group, a 2-fluoro-4-bromophenyl group, a 4-chloro-3-fluorophenyl group, a 2,3,4-trichlorophenyl group or, a 3, 4, 5-trifluorophenyl group, a 2, 3, 4, 5, 6-pentafluorophenyl group, a 2, 4, 6-trimethylphenyl group, a 4-n-butylphenyl group, a 2, 4 group dimethylphenyl, a 2,3-dimethylphenyl group, a 2,6-dimethylphenyl group, a 3,5-dimethylphenyl group, a 2,5-dimethylphenyl group, a 3,5-ditrifluoromethylphenyl group, a 4-n-butoxyphenyl group, a 2,4-dimethoxyphenyl group, a 2,3-dimethoxyphenyl group, a 2,6-dimethoxyphenyl group, a 3,5-dimethoxyphenyl group, a 2,5-dimethoxyphenyl group, a 2, 4,6-trimethoxyphenyl group, a methoxyphenyl 3-chloro-4-group 3, 5-ditrifluorometoxifenilo, group, a-chloro-4-trifluoromethoxyphenyl 2 methyl-4- 3-fluorophenyl group, a-bromo-3-trifluoromethylphenyl 4 group, 2-methylphenyl, a 3-methylphenyl group, a 4-methylphenyl group, a 2-methyl-3-chlorophenyl group, a 3-methyl-4-chlorophenyl group, a 2-chloro-4-methylphenyl group, a 2-group methyl-3-fluorophenyl, a 2-trifluoromethylphenyl group, a 3-trifluoromethylphenyl group, a 4-t group rifluorometilfenilo a 2-pentafluoroetilfenilo pentafluoroetilfenilo 3-4-isopropylphenyl pentafluoroetilfenilo 2-isopropylphenyl 3-isopropylphenyl 4-tert-butylphenyl 2-group, a group, a group, a group, a group, a group, a group, a 3- tert-butylphenyl, a 4-tert-butylphenyl group, a 2-sec-butylphenyl group, a 3-sec-butylphenyl group, a 4-sec-butylphenyl group, a 2-n-heptafluoropropylphenyl group, a 3-n- group heptafluoropropilfenilo group, a 4-n-heptafluoropropilfenilo group, a 4-n-pentylphenyl group, a 4-n-hexylphenyl group, a 2-methoxyphenyl group, a 3-methoxyphenyl group, a 4-methoxyphenyl group, a 3-chloro- 2-methoxyphenyl, a 2-fluoro-3-methoxyphenyl group, a 2-fluoro-4-methoxyphenyl group, a 2,6-dimethoxyphenyl group, a 2, 3, 4-trifluorophenyl group, a group 2, 4, 6 trifluorophenyl, a 2-trifluoromethoxyphenyl group, a 3-trifluoromethoxyphenyl group, a 4-trifluoromethoxyphenyl group, a 3-fluoro-2-trifluoromethoxyphenyl group, a 2-fluoro-3-trifluoromethoxy group phenyl, a 3-fluoro-4-trifluoromethoxyphenyl group, a 3-chloro-2-trifluoromethoxyphenyl group, a 2-chloro-3-trifluoromethoxyphenyl group, a 3-chloro-4-trifluoromethoxyphenyl group, a 2-pentafluoroethoxyphenyl group, a group 3-pentafluoroetoxifenilo group, a 4-pentafluoroetoxifenilo group, a 3-chloro-2-pentafluoroetoxifenilo group, a 2-chloro-3-pentafluoroetoxifenilo group, a 3-chloro-4-pentafluoroetoxifenilo, 2-isopropoxyphenyl group, a 3- isopropoxyphenyl, a 4-isopropoxyphenyl group, a 2-tert-butoxyphenyl group, a 3-tert-butoxyphenyl group, a 4-tert-butoxyphenyl group, a 2-sec-butoxyphenyl group, a 3-sec-butoxyphenyl group, a group 4-sec-butoxyphenyl, a 2-n-heptafluoropropoxyphenyl group, a 3-n-heptafluoropropoxyphenyl group, a 4-n-heptafluoropropoxyphenyl group, a 4-n-pentoxyphenyl group, and a 4-n-hexyloxyphenyl group. The term C1-C6 alkoxy group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-6 alkoxy group C6 substituted or unsubstituted with halogen can be substituted] is used herein to mean the C 1 -C 6 alkoxy phenyl group defined above, wherein 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-C6 alkoxy group substituted or unsubstituted by halogen, can be substituted. Examples of the C 1 -C 6 alkoxy phenyl group may include a benzyloxy group, a 2-phenylethoxy group, a 3-phenylpropoxy group, a 2-phenylpropoxy group, a 4-phenylbutoxy group, a 5-phenylpentoxy group, a 4-phenylpentoxy group , a 6-phenylhexyloxy group, a 2-fluorobenzyloxy group, a 3-fluorobenzyloxy group, a 4-fluorobenzyloxy group, a 2- (2-fluorophenyl) ethoxy group, a 2- (3-fluorophenyl) ethoxy group, a group 2 - (4-fluorophenyl) ethoxy, a 2-chlorobenzyloxy group, a 3-chlorobenzyloxy group, a 4-chlorobenzyloxy group, a 2-fluoro-4-bromobenzyloxy group, a 4-chloro-3-fluorobenzyloxy group, a 2- group chloro-4-fluorobenzyloxy, a 3,4-dichlorobenzyloxy group, a 3,5-dichlorobenzyloxy group, a 2,3-dichlorobenzyloxy group, a 2, 5-dichlorobenzyloxy group, a 2, 3, 4-trichlorobenzyloxy group, a group 3, 4, 5-trifluorobenzyloxy, a 2, 3, 4, 5, 6-pentafluorobenzyloxy group, a 2,4,6-trichlorobenzyloxy group, a 4-isopropylbenzyloxy group, a 4-n-butylbenzyloxy group, a 4- group methylbenzyloxy, a gru po 2-methylbenzyloxy, 3-methylbenzyloxy group, 2,4-dimethylbenzyloxy one group, a 2, 3-dimethylbenzyloxy group, 2, 6-dimethylbenzyloxy group, a 3, 5-dimethylbenzyloxy group, 2, 5-dimethylbenzyloxy a trimethylbenzyloxy 6-etilbeniloxi 4-isopropylbenzyloxy 4-5-ditrifluorometilbenciloxi isopropoxibenciloxi 4-methoxybenzyloxy 4-group 2, 4, a group, a group, a 3, a group, a 4-n-butoxibenciloxi, a group , a 2-methoxybenzyloxy group, a 3-methoxybenzyloxy group, a 2,4-dimethoxybenzyloxy group, a 2,3-dimethoxybenzyloxy group, a 2,6-dimethoxybenzyloxy group, a 3,5-dimethoxybenzyloxy group, a 2, 5 group -dimetoxibenciloxi a 2,4,6-trimetoxibenciloxi group, a 3, 5-ditrifluorometoxibenciloxi group, a 2-isopropoxibenciloxi group, a 3-chloro-4-methoxybenzyloxy, one-chloro-4-trifluoromethoxybenzyloxy 2 group, 3 -methyl-4-fluorobenzyloxy, a 4-bromo-3-trifluoromethylbenzyloxy group, a 2- (2-chlorophenyl) ethoxy group, a 2- (3-chlorophenyl) ethoxy group, a group 2 - (4-chlorophenyl) ethoxy, un-trifluoromethylbenzyloxy 2 trifluoromethylbenzyloxy 3-trifluoromethylbenzyloxy 4-trifluoromethoxybenzyloxy 2-trifluoromethoxybenzyloxy 3-trifluoromethoxybenzyloxy 4-group, a group, a group, a group, a group, a 2- (2 trifluoromethylphenyl) ethoxy group, 2- (3-trifluoromethylphenyl) ethoxy group, 2- (4-trifluoromethylphenyl) ethoxy, 2- (2-trifluoromethoxyphenyl) ethoxy group, 2- (3-trifluoromethoxyphenyl) ethoxy group, 2- (4-trifluoromethoxyphenyl) ethoxy group, a 3- (2-trifluoromethylphenyl) propoxy group, a 3- (3-trifluoromethylphenyl) propoxy group, a 3- (4-trifluoromethylphenyl) propoxy group, a 3- (2-group trifluoromethylphenyl) propoxy group, 3- (3- trifluoromethoxyphenyl) propoxy group, 3- (4- trifluoromethoxyphenyl) propoxy, 4- (3-trifluoromethylphenyl) butoxy group group, 5- (4-trifluoromethylphenyl) pentoxy group, 4- (4-trifluoromethylphenyl) pentoxy, a 4- (4-trifluoromethoxyphenyl) pentoxy group, a 6- (3-trifluoromethylphenyl) hexyloxy group, a group or 6- (4-trifluoromethylphenyl) hexyloxy, and a 6- (4-trifluoromethoxy-phenyl) -hexyloxy group. The term phenoxy group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C 1 -C 6 alkyl group with halogen, and a substituted or unsubstituted C 1 -C 6 alkoxy group with halogen can be substituted] is used herein to mean an unsubstituted phenoxy group or the phenoxy group is defined as above, which comprises 1 to 5 substituents, and preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted C 1 -C 6 alkyl group, and a substituted or unsubstituted C 1 -C 6 alkoxy group replaced with halogen. Examples of the phenoxy group may include a phenoxy group, a 2-fluorophenoxy group, a 3-fluorophenoxy group, a 4-fluorophenoxy group, a 2-chlorophenoxy group, a 3-chlorophenoxy group, a 4-chlorophenoxy group, a 2-group. -bromophenoxy, a 3-bromophenoxy group, a 4-bromophenoxy group, a 2-iodophenoxy group, a 3-iodophenoxy group, a 4-iodophenoxy group, a 2, 3-difluorophenoxy group, a 3, 4-difluorophenoxy group, a group 3, 5-difluorophenoxy, a 2,4-difluorophenoxy group, a 2,6-difluorophenoxy group, a 2,3-dichlorophenoxy group, a 3,4-dichlorophenoxy group, a 3,5-dichlorophenoxy group, a 2 group , 4-dichlorophenoxy, a 2,6-dichlorophenoxy group, a 3, 4, 5-trifluorophenoxy group, a 3, 4, 5-trichlorophenoxy group, a 2, 4, 6-trifluorophenoxy group, a group 2, 4, 6 -trichlorophenoxy, a 2-fluoro-4-bromophenoxy group, a 4-chloro-3-fluorophenoxy group, a 2,3,4-trichlorophenoxy group, a 3, 4, 5-trifluorophenoxy group, a 2, 3, 4 group , 5, 6-pentafluorophenoxy, a 2, 4, 6-trimethylphenoxy group, a 4-n-but group ilfenoxi, a 2, 4-dimethylphenoxy group, a 2,3-dimethylphenoxy group, a 2,6-dimethylphenoxy group, a 3,5-dimethylphenoxy group, a 2,5-dimethylphenoxy group, a 3,5-ditrifluoromethylphenoxy group, a 4-n-butoxyphenoxy group, a 2,4-dimethoxyphenoxy group, a 2,3-dimethoxyphenoxy group, a 2,6-dimethoxyphenoxy group, a 3, 5-dimethoxyphenoxy group, a 2, 5-dimethoxyphenoxy group, a group 2, 4, 6-trimethoxyphenoxy, a 3, 5-ditrifluoromethoxyphenoxy group, a 3-chloro-4-methoxyphenoxy group, a 2-chloro-4-trifluoromethoxyphenoxy group, a 3-methyl-4-fluorophenoxy group, a 4- group bromo-3-trifluoromethylphenoxy, a 2-methylphenoxy group, a 3-methylphenoxy group, a 4-methylphenoxy group, a 2-methyl-3-chlorophenoxy group, a 3-methyl-4-chlorophenoxy group, a 2-chloro- 4-methylphenoxy, a 2-methyl-3-fluorophenoxy group, a 2-trifluoromethylphenoxy group, a 3-trifluoromethylphenoxy group, a 4-trifluoromethylphenoxy group, a 2-pentafluoroethylphenoxy group, a 3-pentafluoroethylphenoxy group, a 4-pentafluoroethylphenoxy group, one GR upo 2-isopropylphenoxy, a 3-isopropylphenoxy group, a 4-isopropylphenoxy group, a 2-tert-butylphenoxy group, a 3-tert-butylphenoxy group, a 4-tert-butylphenoxy group, a 2-sec-butylphenoxy group, a 3-sec-butylphenoxy group, a 4-sec-butylphenoxy group, a 2-n-heptafluoropropylphenoxy group, a 3-n-heptafluoropropylphenoxy group, a 4-n-heptafluoropropylphenoxy group, a 4-n-pentylphenoxy group, a 4 -n-hexylphenoxy, a 2-methoxyphenoxy group, a 3-methoxyphenoxy group, a 4-methoxyphenoxy group, a 3-chloro-2-methoxyphenoxy group, a 2-fluoro-3-methoxyphenoxy group, a 2-fluoro-4 group -methoxyphenoxy, a 2, 6-dimethoxyphenoxy group, a 2, 3, 4-trifluorophenoxy group, a 2,4,6-trifluorophenoxy group, a 2-trifluoromethoxyphenoxy group, a 3-trifluoromethoxyphenoxy group, a 4-trifluoromethoxyphenoxy group, a 3-fluoro-2-trifluoromethoxyphenoxy group, a 2-fluoro-3-trifluoromethoxyphenoxy group, a 3-fluoro-4-trifluoromethoxyphenoxy group, a 3-chloro-2-trifluoromethoxyphenoxy group, a 2-chloro-3-trifluoromethoxy group noxi, a 3-chloro-4-trifluoromethoxyphenoxy group, a 2-entafluoroethoxyphenoxy group, a 3-pentafluoroethoxyphenoxy group, a 4-pentafluoroethoxyphenoxy group, a 3-chloro-2-pentafluoroethoxyphenoxy group, a 2-chloro-3-pentafluoroethoxyphenoxy group , a 3-chloro-4-pentafluoroethoxyphenoxy group, a 2-isopropoxyphenoxy group, a 3-isopropoxyphenoxy group, a 4-isopropoxyphenoxy group, a 2-tert-butoxyphenoxy group, a 3-tert-butoxyphenoxy group, a 4-tert-group -butoxifenoxi, a 2-sec-butoxyphenoxy group, a 3- sec-butoxyphenoxy group, a 4-sec-butoxyphenoxy group, a 2-n-heptafluoropropoxyphenoxy group, a 3-n-heptafluoropropoxyphenoxy group, a 4-n-heptafluoropropoxyphenoxy group, a 4-n-pentoxyphenoxy group, and a 4-n-hexyloxyphenoxy group. The term C 1 -C 6 alkyl group phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a C 1 -C 4 alkylenedioxy group, a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen , and a substituted or unsubstituted C 1 -C 6 alkoxy group with halogen can be substituted] is used herein to mean a C 1 -C 6 alkyl unsubstituted phenyl group, or a group wherein, on the phenyl ring it is constructed the group, up to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a C1-C4 alkylenedioxy group, a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted C1-C6 alkoxy group or not substituted by halogen can be substituted, with the proviso that, when the substituent is a C1-C4 alkylenedioxy group, 1 to 2 substituents are preferably substituted). Examples of the Cl-Cβ phenyl alkyl group can include a benzyl group, a 1-phenethyl group, a 2-phenethyl group, a 3-phenylpropyl group, a 2-phenylpropyl group, a 4-phenylbutyl group, a 5-phenylpentyl group , a 4-phenylpentyl group, a 6-phenylhexyl group, a 2,3-methylenedioxybenzyl group, a 3,4-methylenedioxybenzyl group, a 2-fluorobenzyl group, a 3-fluorobenzyl group, a 4-fluorobenzyl group, a 2-group -chlorobenzyl, a 3-chlorobenzyl group, a 4-chlorobenzyl group, a 2-bromobenzyl group, a 3-bromobenzyl group, a 4-bromobenzyl group, a 2-iodobenzyl group, a 3-iodobenzyl group, a 4-iodobenzyl group , a 2,3-difluorobenzyl group, a 3,4-difluorobenzyl group, a 3,5-difluorobenzyl group, a 2,4-difluorobenzyl group, a 2,6-difluorobenzyl group, a 2,3-dichlorobenzyl group, a 3,4-dichlorobenzyl group, a 3,5-dichlorobenzyl group, a 2,4-dichlorobenzyl group, a 2,6-dichlorobenzyl group, a 2-fluoro-4-bromobenzyl group, a 4-chloro-3-fluoroben group cyl, a 2, 3, 4-trichlorobenzyl group, a 3, 4, 5-trifluorobenzyl group, a 2, 4,6-trichlorobenzyl group, a 4-isopropylbenzyl group, a 4-n-butylbenzyl group, a 4- group methylbenzyl, a 2-methylbenzyl group, a 3-methylbenzyl group, a 2,4-dimethylbenzyl group, a 2,3-dimethylbenzyl group, a 2,6-dimethylbenzyl group, a 3, 5-dimethylbenzyl group, a group 2, 5- dimethylbenzyl, a 2, 4, 6-trimethylbenzyl group, a 3,5-ditrifluoromethylbenzyl group, a 2,3,4,5,6-pentafluorobenzyl group, a 4-isopropoxybenzyl group, a 4-n-butoxybenzyl group, a 4-methoxybenzyl group, a 2-methoxybenzyl group, a 3-methoxybenzyl group, a 2,4-dimethoxybenzyl group, a 2,3-dimethoxybenzyl group, a 2,6-dimethoxybenzyl group, a 3,5-dimethoxybenzyl group, a 2,5-dimethoxybenzyl group, a 2, 4,6-trimethoxybenzyl group, a 3,5-ditrifluoromethoxybenzyl group, a 2-isopropoxybenzyl group, a 3-chloro-4-methoxybenzyl group, a 2-chloro-4- group trifluoromethoxybenzyl, a 3-methyl-4-fluorobe group ncilo, a 4-bromo-3-trifluoromethylbenzyl group, a 2-trifluoromethylbenzyl group, a 3-trifluoromethylbenzyl group, a 4-trifluoromethylbenzyl group, a 2-pentafluoroethylbenzyl group, a 3-pentafluoroethylbenzyl group, a 4-pentafluoroethylbenzyl group, a group 2-trifluoromethoxybenzyl, a 3-trifluoromethoxybenzyl group, a 4-trifluoromethoxybenzyl group, a 2-pentafluoroethoxybenzyl group, a 3-pentafluoroethoxybenzyl group, a 4-pentafluoroethoxybenzyl group, a 2- (2-trifluoromethylphenyl) ethyl group, a 2- ( 3-trifluoromethylphenyl) ethyl, a 2- (4-trifluoromethylphenyl) ethyl group, m 2- (2-trifluoromethoxyphenyl) ethyl group, a 2- (3-trifluoromethoxyphenyl) ethyl group, a 2- (4-trifluoromethoxyphenyl) ethyl group, a 2- (2-pentafluoroethoxyphenyl) ethyl group, a 2- (3-pentafluoroethoxyphenyl) ethyl group, a 2- (4-pentafluoroethoxyphenyl) ethyl group, a 3- (2-trifluoromethylphenyl) propyl group, a 3- (3-trifluoromethylphenyl) propyl group, a 3- (4-trifluoromethylphenyl) propyl group, a 3- (2-trifluoromethoxyphenyl) propyl group, a 3-group ( 3-trifluoromethoxyphenyl) propyl, a 3- (4-trifluoromethylphenyl) propyl group, a 3- (3-pentafluoroethoxyphenyl) propyl group, a 3- (4-pentafluoroethoxyphenyl) propyl group, a 4- (3-pentafluoroethoxyphenyl) butyl group, a 5- (4-trifluoromethylphenyl) pentyl group, a 4- (4-trifluoromethylphenyl) pentyl group, a 4- (4-trifluoromethoxyphenyl) pentyl group, a 6- (3-trifluoromethylphenyl) hexyl group, a group 6- (4 -trifluoromethylphenyl) hexyl and a 6- (4-trifluoromethoxyphenyl) hexyl group. Examples of the C1-C6 alkyl piperidyl group can include a piperidin-1-ylmethyl group, a piperidin-2-ylethyl group, a piperidin-3-ylpropyl group, a piperidin-4-ylbutyl group, a piperidin-1-ylpentyl group and a piperidin-2-ylhexyl group. An amino group, wherein at least one selected from the group consisting of a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or not substituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted], a C1-C6 alkyl group, and a C1-C6 alkyl group phenyl [wherein, on the phenyl ring, at least one selected of the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], can be substituted as a substituent, can be an amino group wherein 1 6 2 groups selected from the group consisting of a phenyl group [wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a Cl alkyl group -Cβ substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], a Cl-Cß alkyl group, and a Cl-Cβ alkyl phenyl group [wherein, in the phenyl ring , 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can to be replaced], can be replaced as substituents. Examples of the amino group may include an amino group, a methylamino group, a dimethylamino group, an ethylamino group, a diethylamino group, an n-propylamino group, a n-butylane group, an n-pentylamino group, an n-hexylamino group , a phenylamino group, a (4-chlorophenyl) amino group, a group (4-bromophenyl) amino, a (2,4-dichlorophenyl) amino group, a (2,4,6-trichlorophenyl) amino group, a (2,3,4,5,6-pentafluorophenyl) amino group, a group (4-fluorophenyl) amino, a (4-iodophenyl) amino group, a (4-chlorophenyl) amino group, a (3-methylphenyl) amino group, a (2-trifluoromethylphenyl) amino group, a (3-trifluoromethylphenyl) group amino, a group (4-trifluoromethylphenyl) amino, a (3,4-dimethylphenyl) amino group, a (3,4,5-trimethylphenyl) amino group, a (2-methoxyphenyl) amino group, a (4-trifluoromethoxyphenyl) group amino), a group (3-trifluoromethoxyphenyl) amino, a group (3,5-dimethoxyphenyl) amino, a group (2,5-dimethoxyphenyl) amino, a group (2,4,6-trimethoxyphenyl) amino, a group N -methyl-N- (4-trifluoromethylphenyl) amino, a N-ethyl-N- (4-trifluoromethoxyphenyl) amino group, a 1-phenethylamino group, a 2-phenethylamino group, a 3-phenylpropylamino group, a 2-phenylpropylamino group , a 4-phenylbutylamino group, a 5-phenylpentylamino group, a 4-phenylpentylamino group, a group 6- phenylhexylamino, a 2-fluorobenzylamino group, a 3-fluorobenzylamino group, a N-phenyl-N- (4-fluorobenzyl) amino group, a 2-chlorobenzylamino group, a 3-chlorobenzylamino group, 4-chlorobenzylamino group 2 -bromobencilamino, an N-methyl-N- (3-bromobenzyl) amino, 4-bromobenzylamino group, one 3-iodobenzylamino iodobenzylamino-2-iodobenzylamino 4 group, a group, a group, a 2, 3-difluorobenzylamino, a 3, 4-difluorobenzylamino group, a 3,5-difluorobenzylamino group, a 2,4-difluorobenzylamino group, a 2,6-difluorobenzylamino group, a 2,3-dichlorobenzylamino group, a 3,4-dichlorobenzylamino group, a group 3, 5-dichlorobenzylamine, a 2,4-dichlorobenzylamine group, a 2-dichlorobenzylamine group, a 2-fluoro-4-bromobenzylamino group, a 4-chloro-3-fluorobenzylamino group, a group 2, 3, 4- trichlorobenzylamine, a 3, 4, 5-trifluorobenzylamino group, a 2,4,6-trichlorobenzylamino group, a 4-isopropylbenzylamino group, a 4-n-butylbenzylamino group, a 4-m group ethylbenzylamino, a 2-methylbenzylamino group, a 3-methylbenzylamino group, a 2,4-dimethylbenzylamino group, a 2,3-dimethylbenzylamino group, a 2,6-dimethylbenzylamino group, a 3, 5-dimethylbenzylamino group, a group 2, 5- dimethylbenzylamino a-trimetilbencilamino May 6-ditrifluorometilbencilamino-isopropoxybenzylamino 4 group 2, 4, a 3, a 2,3,4,5,6- pentafluorobencilamino group, a group, a 4-n-butoxibencilamino, 1 to 4 methoxybenzylamino group, a-methoxybenzylamino 2 methoxybenzylamino 3-dimethoxy-4-dimethoxybenzyl 3-5-dimethoxybenzylamino group, a group, a 2, a 2, a 2, 6-dimethoxybenzylamino group, a 3, 2,5-dimethoxy one group, 6-trimethoxy-isopropoxybenzylamino 2 chloro-4-methoxybenzylamino 3-chloro-4- 2-group 2, 4, a 3, 5-ditrifluorometoxibencilamino, a group, a group, a group trifluoromethoxybenzylamine, a 3-methyl-4-fluorobenzylamino group, a 4-bromo-3-trifluoromethylbenzylamino group, a 2-trifluoride group oromethylbenzylamino, a 3-trifluoromethylbenzylamino group, a 4-trifluoromethylbenzylamino group, a 2-pentafluoroethylbenzylamino group, a 3-pentafluoroethylbenzylamino group, a 4-pentafluoroethylbenzylamino group, a 2-trifluoro-methoxybenzylamino group, a 3-trifluoromethoxybenzylamino group, a 4-trifluoromethoxybenzylamino group a 2-pentafluoroetoxibencilamino pentafluoroetoxibencilamino 3-group, a 4- pentafluoroetoxibencilamino group, an group 2- (2-trifluoromethylphenyl) ethylamino group, 2- (3-trifluoromethylphenyl) ethylamino, 2- ethylamino group (4-trifluoromethylphenyl) a group 2- (2-trifluoromethoxyphenyl) ethylamino group, 2- (3-trifluoromethoxyphenyl) ethylamino, 2- ethylamino group (4 trifluoromethoxyphenyl) group, 2- (2 pentafluoroetoxifenil) ethylamino, 2- ethylamino group (3 pentafluoroetoxifenil) a 2- (4-pentafluoroethoxyphenyl) ethylamino group, a 3- (2-trifluoromethylphenyl) propylamino group, a 3- (3-trifluoromethylphenyl) propylamino group, a 3- (4-trifluoromethyl) group phenyl) propylamino, a 3- (2-trifluoromethoxyphenyl) propylamino group, a 3- (3-trifluoromethoxyphenyl) propylamino group, a 3- (4-trifluoromethoxyphenyl) propylamino group, a 3- (3-pentafluoroethoxyphenyl) propylamino group, a 3- (3-group 4-pentafluoroetoxifenil) propylamino, 4- (3-pentafluoroetoxifenil) butylamino group, a 5- (4-trifluoromethylphenyl) pentylamino group, a pentylamino group 4- (4-trifluoromethylphenyl) pentylamino group 4- (4-trifluoromethoxyphenyl) a 6- (3-trifluoromethylphenyl) hexylamino group, a 6- (4-trifluoromethylphenyl) hexylamino group, a 6- (4-trifluoromethoxyphenyl) hexylamino group, a N-methyl-N-phenylamino group, a N-methyl- N-benzylamino, and an N-phenyl-N-benzylamino group. Examples of the carbamoyloxy group (wherein, in the amino group, at least one selected from the group consisting of a C1-C6 alkyl group and a phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted) can include carbamoyloxy groups such as a carbamoyloxy group, one phenylcarbamoyloxy group, a 2-fluorofenilcarbamoiloxi fluorofenilcarbamoiloxi 3-fluorofenilcarbamoiloxi 4-clorofenilcarbamoiloxi 2-clorofenilcarbamoiloxi 3-clorofenilcarbamoiloxi 4-bromofenilcarbamoiloxi 2-group, a group, a group, a group, a group, a group, a group, a 3- bromophenylcarbamoyloxy, a 4-bromophenylcarbamoyloxy group, a 2-iodophenylcarbamoyloxy group, a 3-iodophenylcarbamoyloxy group, a 4-iodophenylcarbamoyloxy group, a 2, 3-difluorophenylcarbam group oyloxy group, 3, 4-difluorofenilcarbamoiloxi, a 3,5-difluorofenilcarbamoiloxi, 2,4-difluorofenilcarbamoiloxi group, a 2, ß-difluorofenilcarbamoiloxi, a 2,3-diclorofenilcarbamoiloxi group, a 3,4- diclorofenilcarbamoiloxi group, a 3,5-dichlorophenylcarbamoyloxy group, a 2,4-dichlorophenylcarbamoyloxy group, a 2,6-dichlorophenylcarbamoyloxy group, a 3,4,5-trifluorophenylcarbamoyloxy group, a 2,3,4,5,6-pentafluorophenylcarbamoyloxy group, a group 3,4,5-triclorofenilcarbamoiloxi a 2,4,6-trifluorofenilcarbamoiloxi group, a 2,4,6-triclorofenilcarbamoiloxi group, a 2-metilfenilcarbamoiloxi group, a 3-metilfenilcarbamoiloxi group, a 4-metilfenilcarbamoiloxi a ggrruuppoo 2- methyl-3-clorofenilcarbamoiloxi a metilfenilcarbamoiloxi 2-chloro-4-group, 3-methyl-4-clorofenilcarbamoiloxi, a group, a 2-methyl-3-fluorofenilcarbamoiloxi group, a 2-trifluorometilfenilcarbamoiloxi group, a 3-trifluorometilfenilcarbamoiloxi, a group methylcarbamoyloxy, an eti group lcarbamoiloxi, an n-propylcarbamoyloxy group, an n-butylcarbamoyloxy group, an n-hexilcarbamoiloxi, an n-penilcarbamoiloxi, an N-methyl-N-phenylcarbamoyloxy group, an N, N-dimethylcarbamoyloxy group, an N-methyl- N-ethylcarbamoyloxy, an N- (2-fluorophenyl) -N-methylcarbamoyloxy group, an N- (3-fluorophenyl) -N-methylcarbamoyloxy group, a N- (4-fluorophenyl) -N-methylcarbamoyloxy group, a N- group (2-chlorophenyl) -N-methylcarbamoyloxy, an N- (3-chlorophenyl) -N-methylcarbamoyloxy group, an N- (4-chlorophenyl) -N-methylcarbamoyloxy group, an N- (4-bromophenyl) -N-methylcarbamoyloxy group, an N- (2-iodophenyl) -N-methylcarbamoyloxy group, an N- (3-iodophenyl) -N-methylcarbamoyloxy group, a N- (4-iodophenyl) -N-methylcarbamoyloxy group, a N- (2,3-difluorophenyl) -N group -methylcarbamoyloxy, an N- (3,4-difluorophenyl) -N-methylcarbamoyloxy group, an N- (3,5-difluorophenyl-N-methylcarbamoyloxy group, a N- (2,4-difluorophenyl) -N-methylcarbamoyloxy group, a group N- (2,6-difluorophenyl-N-methylcarbamoyloxy, an N- (2,3-dichlorophenyl-N-methylcarbamoyloxy group, an N- (3,4-dichlorophenyl) -N-methylcarbamoyloxy group, an N- (3,5-dichlorophenyl) -N-methylcarbamoyloxy group, a N- group ( 2,4-dichlorophenyl-N-methylcarbamoyloxy, an N- (2,6-dichlorophenyl) -N-methylcarbamoyloxy group, an N- (3,4,5-trifluorophenyl) -N-methylcarbamoyloxy group, a N- (3) group, 4, 5-trichlorophenyl-N-methylcarbamoyloxy, a N- (2,4,6-trifluorophenyl) -N-methylcarbamoyloxy group, a N- (2,4,6-trichlorophenyl) -N-methylcarbamoyloxy group, a N- group ( 2-methylphenyl-N-methylcarbamoyloxy, an N- (3-methylphenyl-N-methylcarbamoyloxy group, an N- (4-methylphenyl-N-methylcarbamoyloxy, an N- (2-methyl-3-chlorophenyl-N-methylcarbamoyloxy) group , an N- (3-methyl-4-chlorophenyl) -N-methylcarbamoyloxy group, an N- (2-chloro-4-methylphenyl) -N-methylcarbamoyloxy group, a N- (2-methyl-3-fluorophenyl) group - N-methylcarbamoyloxy, an N- (2-trifluoromethylphenyl) -N-methylcarbamoyloxy group, a N- (4-trifluoromethylphenyl) -N-methylcarbamoyloxy group, an N-phenyl-N-phenylcarbamoyloxy group, a N-phenyl-N- group (2-fluorophenyl) carbamoyloxy, an N-phenyl-N- (3-fluorophenyl) carbamoyloxy group, an N-phenyl-N- (4-fluorophenyl) carbamoyloxy group, a N-phenyl-N- (2-chlorophenyl) group Carbamoyloxy, an N-phenyl-N- (3-chlorophenyl) carbamoyloxy group, an N-phenyl-N- (4-chlorophenyl) carbamoyloxy group, a N-phenyl-N- (2 -bromophenyl) carbamoyloxy, an N-phenyl-N- (3-bromophenyl) carbamoyloxy group, an N-phenyl-N- (4-bromophenyl) carbamoyloxy group, an N-phenyl-N- (2-iodophenyl) carbamoyloxy group, an N-phenyl-N- (3-iodophenyl) carbamoyloxy group, an N-phenyl-N- (4-iodophenyl) carbamoyloxy group, m N-phenyl-N- (2,3-difluorophenyl) carbamoyloxy group, a N group -phenyl-N- (3,4-difluorophenyl) carbamoyloxy, an N-phenyl-N- (3,5-difluorophenyl) carbamoyloxy group, an N-phenyl-N- (2,4-difluorophenyl) carbamoyloxy group, a group N-phenyl-N- (2,6-difluorophenyl) carbamoyloxy, an N-phenyl-N- (2,3-dichlorophenyl) carbamoyloxy group, an N-phenyl-N- (3,4-dichlorophenyl) carbamoyloxy group, an N-phenyl-N- (3,5-dichlorophenyl) carbamoyloxy group, an N-phenyl-N- (2,4-dichlorophenyl) carbamoyloxy group, an N-phenyl-N- (2,6-dichlorophenyl) carbamoyloxy group, a N-phenyl-N- (3,4-, 5-trifluorophenyl) carbamoyloxy group, an N-phenyl-N- (3,4,5-trichlorophenyl) carbamoyloxy group, an N-phenyl-N- group (2,4 , 6-trifluorophenyl) carbamoyloxy, an N-phenyl-N- (2, 4, 6-tr group) iclorophenyl) carbamoyloxy, an N-phenyl-N- (2-methylphenyl) carbamoyloxy group, an N-phenyl-N- (3-methylphenyl) carbamoyloxy group, an N-phenyl-N- (4-methylphenyl) carbamoyloxy group, an N-phenyl-N- (2-methyl-3-chlorophenyl) carbamoyloxy group, an N-phenyl-N- (3-methyl-4-chlorophenyl) carbamoyloxy group, an N-phenyl-N- (2-chloro- 4-methylphenyl) -carbamoyloxy, an N-phenyl-N- (2-methyl-3-fluorophenyl) carbamoyloxy group, an N-phenyl-N- (2-trifluoromethylphenyl) carbamoyloxy group, a N-phenyl-N- group ( 3-trifluoromethylphenyl) carbamoyloxy, an N-phenyl-N- (4-trifluoromethylphenyl) carbamoyloxy group, a 2-pentafluoroethylphenylcarbamoyloxy group, a 3-pentafluoroethylphenylcarbamoyloxy group, a 4-pentafluoroethylphenylcarbamoyloxy group, a 2-isopropylphenylcarbamoyloxy group, a 3-isopropylphenylcarbamoyloxy group , a 4-isopropylphenylcarbamoyloxy group, a 1-2-tert-butylphenylcarbamoyloxy group, a group <or 3-tert-butylphenylcarbamoyloxy, a group < or 4 - tert-butylphenylcarbamoyloxy a 2-sec-butylphenylcarbamoyloxy group, a 3-sec-butylphenylcarbamoyloxy group, a 4-sec-butylphenylcarbamoyloxy group, a 2-n- heptafluoropropilfenilcarbamoiloxi, a 3-n- heptafluoropropilfenilcarbamoiloxi, a group 4-n-heptafluoropropilfenilcarbamoiloxi group, a 4-n-pentylphenylcarbamoyloxy a 4-n-hexilfenílcarbamoiloxi group, a 4-group dimetilfenilcarbamoiloxi 2, a 2,4,6-trimetilfenilcarbamoiloxi group, a 3,4-dimetoxifenilcarbamoiloxi group, 3,4,5-trimetoxifenilcarbamoiloxi-metoxifenilcarbamoiloxi 2 metoxifenilcarbamoiloxi 3-4-metoxifenilcarbamoiloxi, a group, a group, a group, un-methoxy-3-clorofenilcarbamoiloxi 2, a-fluoro-3-metoxifenilcarbamoiloxi 2 group, a group 2- fluoro-4-metoxifenilcarbamoiloxi a trifluorofenilcarbamoiloxi 4--trifluorofenilcarbamoiloxi A trifluorometoxifenilcarbamoiloxi 2-trifluorometoxifenilcarb 3-group 2, 6-dimetoxifenilcarbamoiloxi group, 2, 3, a 3, 4, a group, group uunn amoiloxi, 4-trifluorometoxifenilcarbamoiloxi uunn group, 2-pentafluoroetoxifenilcarbamoiloxi uunn group, r \ u mn 3-pentafluoroetoxifenilcarbamoiloxi group, r ^ 4-pentafluoroetoxifenilcarbamoiloxi uann group, 2-isopropoxifenilcarbamoiloxi umn group, a 3- isopropoxifenilcarbamoiloxi, 4- isopropoxifenilcarbamoiloxi group, -tert-butoxifenilcarbamoiloxi 2 group, a 3-tert-butoxifenilcarbamoiloxi a-tert-butoxifenilcarbamoiloxi 4 group, a-sec-butoxifenilcarbamoiloxi 2 group, a 3-sec-butoxifenilcarbamoiloxi group, 4-sec-butoxifenilcarbamoiloxi group, 2 -n-heptafluoropropoxyphenylcarbamoyloxy, a 3-n-heptafluoropropoxyphenylcarbamoyloxy group, a 4-n-heptafluoropropoxyphenylcarbamoyloxy group, a 4-n-pentyloxyphenylcarbamoyloxy group, and a 4-n-hexyloxyphenylcarbamoyloxy group (wherein, in the amino group, 1 or 2 groups selected from the group consisting of a C1-C6 alkyl group and a phenyl group [wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 ha 3 groups selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted). Examples of the C1-C10 alkyl group substituted or unsubstituted by halogen may include: the substituted or unsubstituted C1-C6 alkyl group with halogen described above; C1-C10 alkyl groups such as a heptyl group, an octyl group, a nonyl group, a decyl group, a 7- fluoroheptyl group, a 7,7,6-trifluoroheptyl group, a group 7, 7, 7, 6, 6 , 5, 5-heptafluoroheptilo, a 8-clorooctilo, a 8, 8-dibromooctilo group, 6, 7, 8-trifluorooctilo, a group 8, 8, 8, 7, 7, 6, 6-heptafluorooctilo a group 8,8,8,7,7-pentachlorooctyl, a 9-iodononyl group, a 9,9-dibromononyl group, a 9, 9, 9, 8, 8-pentachlorononyl group, a group 9, 9, 9, 8 , 8, 7, 7-heptafluorononyl, a 10-chlorodecyl group, a 10,10-dibromodecyl group, a 10,10,10,9-tetrachlorodecline group, and a group 10,10,10,9,9,9, 8,8-heptafluorodecyl; and C1-C10 alkyl groups wherein 1 to 7 halogen atoms are substituted. In addition to the phenyl group described above (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted C1-C6 alkoxy group or unsubstituted with halogen can be substituted), examples of the phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a C1-C4 alkylenedioxy group, a cyano group, a phenoxy group, an alkylthio group C1-C6, a C1-C6 alkanoyl group, a phenyl group, a C1-C6 alkyl group phenyl, a halogen atom, a C1-C10 alkyl group substituted or unsubstituted with halogen, and a substituted C1-C10 alkoxy group or unsubstituted with halogen can be substituted] can also include phenyl groups such as a 4-cyanophenyl group, a 3-cyanophenyl group, a 2-cyanophenyl group, a 3, 4-dicyanophenyl group, a 3,4,5-tricyophenyl group, a 4-phenoxyphenyl group, a 3-phenoxyphenyl group, a 2-phenoxyphenyl group, a 3,4-difenoxifenilo, trifonoxifenilo 6-methylthiophenyl 4-methylthiophenyl 3-methylthiophenyl 2-a 2, 4, a group, a group, a group, a 3, -dimetiltiofenilo group, 2, 4, 6- trimetiltiofenilo, 4-acetylphenyl group, 3-acetylphenyl group, a 2-acetylphenyl, 3.4-diacetilfenilo group, a 2, 4, 6-triacetilfenilo, a 4-biphenyl, 3-biphenyl group, one-biphenyl 2 group, a 3, 4-difenilfenilo group, 2, 4, 6-trifenilfenilo group, a 4-heptiloxifenilo group, a 3-octyloxyphenyl group, a 2-noniloxifenilo group, a 4-deciloxifenilo, a group 2,4-diheptiloxifenilo a triheptiloxifenilo 6-group 2, 4, a 4- (7, 7-dicloroheptiloxi) phenyl, 4-benzylphenyl group, a 3-benzylphenyl group, a 2-benzylphenyl group, a 2 , 4-dibenzylphenyl, a group 2, 4 , 6-tribenylphenyl, a 4-octylphenyl group, a 4-heptylphenyl group, a 3-octylphenyl group, a 3- (8,8,8-trifluorooctyl) phenyl group, a 2-nonylphenyl group, a 4-decylphenyl group, 2,4-dioctylphenyl group, a 6-group trioctildifenilo 2, 4, a 4-phenyl-3-chlorophenyl group, 4-phenoxy-3-methylthiophenyl group, a 4-heptyloxy-3-trifluoromethoxyphenyl, a group 4-octyl-2-trifluoromethylphenyl, a 4-benzyl-2-methylphenyl group, a 3,4-ethylenedioxyphenyl group, and a 3,4-methylenedioxyphenyl group [wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of the C1-C4 alkylenedioxy group described above, cyano group, phenoxy group, the C1-C3 alkylthio group described above, the C1-C6 alkanoyl group described above, phenyl group, the C1-6 alkyl group C6 phenyl described above, the halogen atom described above, the substituted or unsubstituted Cl-Cß alkyl group with halogen described above, and the Cl-Cβ sub-alkoxy group The substituted or unsubstituted halogen described above can be substituted (in a case where the substituent is a C1-C4 alkylenedioxy group, 1 or 2 groups are preferably substituted)). Examples of the C1-Cß alkyl group substituted with carbamoyloxy (wherein, in the amino group, at least one selected from the group consisting of a Cl-Cβ alkyl group, a Cl-Cβ alkyl group phenyl, a C3-C8 cycloalkyl group , a naphthyl group, a 2,3-dihydro-lH-indenyl group, a 2,3-dihydrobenzofuryl group, and a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of an alkylenedioxy group C1-C4, a cyano group, a phenoxy group, a C1-C6 alkylthio group, a Cl-Cβ alkanoyl group, a phenyl group, a C1-C6 alkyl group phenyl, a halogen atom, a substituted C1-C10 alkyl group or unsubstituted with halogen, and a C1-C10 alkoxy group substituted or unsubstituted with halogen can be substituted], can be substituted), can include C1-C6 alkyl groups substituted with carbamoyloxy such as a carbamoyloxymethyl group, a 2-carbamoyloxyethyl group , a 1-carbamoyloxyethyl group, a 3-carbamoyloxypropyl group, a Group 4-carbamoiloxibutilo group, a 5-carbamoiloxipentilo group, a 6-carbamoiloxihexilo a fenilcarbamoiloximetilo group, a 2-metilfenilcarbamoiloximetilo group, a 3-metilfenilcarbamoiloximetilo group, a 4-metilfenilcarbamoiloximetilo, a 2,3-dimetilfenilcarbamoiloximetilo group, a 2 , 4-dimethylphenylcarbamoyloxymethyl, a 2,6-dimethylphenylcarbamoyloxymethyl group, a 2,4,6-trimethylphenylcarbamoyloxymethyl group, a 2-trifluoromethylphenylcarbamoyloxymethyl group, a 3-trifluoromethylphenylcarbamoyloxymethyl group, a 4-trifluoromethylphenylcarbamoyloxymethyl group, a 2,3-ditrifluoromethylphenylcarbamoyloxymethyl group, a 2,4-ditrifluoromethylphenylcarbamoyloxymethyl group, a 2,6-ditrifluoromethylphenylcarbamoyloxymethyl group, a 2-pentafluoroethylphenylcarbamoyloxymethyl group, a 3-pentafluoroethylphenylcarbamoyloxymethyl groupGroup, a 4-pentafluoroetilfenilcarbamoiloximetilo group, 2- (n- propylphenyl) carbamoyloxymethyl group, a 3- (n-propylphenyl) carbamoyloxymethyl group, a 4- (n-propylphenyl) carbamoyloxymethyl group, a 2- (phenylcarbamoyloxy) ethyl, one 2- (3-trifluoromethylphenylcarbamoyloxy) ethyl group, a 2- (4-trifluoromethylphenylcarbamoyloxy) ethyl group, a - (2,3-ditrifluoromethylphenylcarbamoyloxy) ethyl group, a - (2,4-ditrifluoromethylphenylcarbamoyloxy) ethyl group, a - (2) group 6-ditrifluorometilfenilcarbamoiloxi) ethyl group, 2- (2-pentafluoroetilfenilcarbamoiloxi) ethyl group, 2- (3-pentafluoroetilfenilcarbamoiloxi) ethyl group, 2- (4-pentafluoroetilfenilcarbamoiloxi) ethyl group, a 3- (phenylcarbamoyloxy) propyl, one group 3- (3-trifluorometilfenilcarbamoiloxi) propyl, 3- (4-trifluorometilfenilcarbamoiloxi) propyl group, a 3- (2,3-ditrifluorometilfenilcarbamoiloxi) propyl group, 3- (2,4-ditrifluorometilfenilcarbamoiloxi) propyl group, 3 - (2,6-ditrifluoromethylphenylcarbamoyloxy) ) -propyl group, 3- (2-pentafluoroetilfenilcarbamoiloxi) propyl, 3- (3-pentafluoroetilfenilcarbamoiloxi) propyl group, a 3- (4-pentafluoroetilfenilcarbamoiloxi) propyl group, a 4- (4-trifluorometilfenilcarbamoiloxi) butyl, one group 5- (4-trifluorometilfenilcarbamoiloxi) pentyl, 6- (4-trifluorometilfenilcarbamoiloxi) hexyl group, a (2-fluorofenilcarbamoiloxi) methyl group, 2- (3- fluorofenilcarbamoiloxi) ethyl group one l- (4 fluorofenilcarbamoiloxi) ethyl group, 3- (2 clorofenilcarbamoiloxi) propyl group, 4- (3 clorofenilcarbamoiloxi) butyl group, 5- (4 clorofenilcarbamoiloxi) pentyl group, 6- (2 bromofenilcarbamoiloxi) hexyl group, (3 bromofenilcarbamoiloxi) methyl, a 2- (4-bromophenylcarbamoyloxy) ethyl group, a 1- (2-iodophenylcarbamoyloxy) ethyl group, a 3- (3-iodophenylcarbamoyloxy) propyl group, a 4- (4-iodophenylcarbamoyloxy) butyl group, a 5 - group 2,3-difluorophenylcarbamoyloxy) pentyl, a 6 - (3,4-difluorophenylcarbamoyloxy) hex group ilo, a group (3,5-difluorophenylcarbamoyloxy) methyl, a 2- (2,4-difluorophenylcarbamoyloxy) ethyl group, a 1- (2,6-difluorophenylcarbamoyloxy) ethyl group, a group 3 - (2,3 -dichlorophenylcarbamoyloxy) propyl, a 4 - (3,4-dichlorophenylcarbamoyloxy) butyl group, a 5- (3,5-dichlorophenylcarbamoyloxy) pentyl group, a 6- (2,4-dichlorophenylcarbamoyloxy) hexyl group, a group (2) , 6-dichlorophenylcarbamoyloxy) methyl, a 2- (3, 4,5-trifluorophenylcarbamoyloxy) ethyl group, a 1- (2,3,4,5,6-pentafluorophenylcarbamoyloxy) ethyl group, a 3- (3,4 group, 5-trichlorophenylcarbamoyloxy) propyl, a 4- (2,4,6-trifluorophenylcarbamoyloxy) butyl group, a 5- (2,4-, 6-trichlorophenylcarbamoyloxy) pentyl group, a (2-methyl-3-chlorophenylcarbamoyloxy) methyl group, a group (3-methyl-4-chlorophenylcarbamoyloxy) methyl, a (2-chloro-4-methylphenylcarbamoyloxy) methyl group, a (2-methyl-3-fluorophenylcarbamoyloxy) methyl group, an ethylcarbamoyloxymethyl group, an n-butylcarbamoyloxymethyl group, a group n-hexilcarbamo iloxymethyl, an n-pentylcarbamoyloxymethyl group, an N-methyl-N-phenylcarbamoyloxymethyl group, a N, N-dimethylcarbamoyloxymethyl group, an N-methyl-N-ethylcarbamoyloxymethyl group, a 2- (N- (2-fluorophenyl) -N group) -methylcarbamoyloxy) ethyl, a 1- (N- (3-fluorophenyl) -N-methylcarbamoyloxy) ethyl group, a 3- (N- (4-fluorophenyl) -N-methylcarbamoyloxy) propyl group, a 4- (N-) group (2-chlorophenyl) -N-methylcarbamoyloxy) butyl, a 5- (N- (3-chlorophenyl) -N-methylcarbamoyloxy) pentyl group, a 6- (N- (4-chlorophenyl) -N-methylcarbamoyloxy) hexyl group, a group (N- (4-bromophenyl) -N-methylcarbamoyloxy) methyl, a 2- (N- (2-iodophenyl) -N-methylcarbamoyloxy) ethyl group, a 1- (N- (3-iodophenyl) -N group -methylcarbamoyloxy) ethyl, a 3- (N- (4-iodophenyl) -N-methylcarbamoyloxy) propyl group, a 4- (N- (2,3-difluorophenyl) -N-methylcarbamoyloxy) butyl group, a group 5- ( N- (3,4-difluorophenyl) -N-methylcarbamoyloxy) pentyl, a 6- (N- (3,5-difluorophenyl) -N-methylcarbamoyloxy) hexyl group, a group (N- (2, 4 -difluorophenyl) -N-methylcarbamoyloxy) methyl, a 2- (N- (2,6-difluorophenyl) -N-methylcarbamoyloxy) ethyl group, a 1- (N- (2,3-dichlorophenyl) -N-methylcarbamoyloxy) ethyl group, a 3- (N-) group (3,4-dichlorophenyl) -N-methylcarbamoyloxy) propyl, a group (N- (3,5-dichlorophenyl) -N-methylcarbamoyloxy) methyl, a group 4- (N- (2,4-dichlorophenyl) -N- methylcarbamoyloxy) butyl group, 5- (N- (2, 6-dichlorophenyl) -N-methylcarbamoyloxy) pentyl group, 6- (N- (3,4, 5-trifluorophenyl) -N-methylcarbamoyloxy) hexyl group (N- (3, 4, 5-trichlorophenyl) -N-methylcarbamoyloxy) methyl, a 2- (N- (2,4,6-trifluorophenyl) -N-methylcarbamoyloxy) ethyl group, a group 1- (N- ( 2,4,6-trichlorophenyl) -N-methylcarbamoyloxy) ethyl, a 3- (N- (2-methylphenyl) -N-methylcarbamoyloxy) propyl group, a 4- (N- (3-methylphenyl) -N-methylcarbamoyloxy group butyl, a 5- (N- (4-methylphenyl) -N-methylcarbamoyloxy) hexyl group, a 6- (N- (2-methyl-3-chlorophenyl) -N-methylcarbamoyloxy) hexyl group, a group (N-) (3-methyl-4-chlorophenyl) -N-methylcarbamoyloxy) methyl, a group 2 - (N- (2-Chloro-4-methylphenyl) -N-methylcarbamoyloxy) ethyl, a 1- (N- (2-methyl-3-fluorophenyl) -N-methylcarbamoyloxy) ethyl group, a 3- (N-) group (2-trifluoromethylphenyl) -N-methylcarbamoyloxy) propyl group, 4- (N- (4-trifluoromethylphenyl) -N-methylcarbamoyloxy) butyl group, 2- (N- (4-trifluoromethylphenyl) -N-methylcarbamoyloxy) ethyl, one group 5- (N-phenyl-N-phenylcarbamoyloxy) pentyl, 6- (N-phenyl-N- (2-fluorophenyl) carbamoyloxy) hexyl group, an (N-phenyl-N- (3-fluorophenyl) carbamoyloxy ethyl), a 2- (N-phenyl-N- (4-fluorophenyl) -carbamoyloxy) ethyl group, a 1- (N-phenyl-N- (2-chlorophenyl) carbamoyloxy) ethyl group, a group 1- (N - phenyl-N- (3-chlorophenyl) carbamoyloxy) ethyl, a 3- (N-phenyl-N- (4-chlorophenyl) carbamoyloxy) propyl group, a 4- (N-phenyl-N- (2-bromophenyl) group) carbamoyloxy) butyl, a 5- (N-phenyl-N- (3-bromophenyl) carbamoyloxy) pentyl group, a 6- (N-phenyl-N- (4-bromophenyl) -carbamoyloxy) hexyl group, a group (N- phenyl-N- (2-iodophenyl) carbamoyloxy) methyl, a 1- (N-Phenyl-N- (3-iodophenyl) carbamoyloxy) ethyl group, a 2- (N-phenyl-N- (4-iodophenyl) carbamoyloxy) ethyl group, a 1- (N-phenyl-N-) group (2, 3-difluorophenyl) carbamoyloxy) ethyl, 3- (N-phenyl-N- (3, 4-difluorophenyl) carbamoyloxy) propyl group, a 4- (N-phenyl-N- (3, 5-difluorophenyl group ) -carbamoyloxy) butyl, a pentyl group 5- (N-phenyl-N- (2, 4-difluorophenyl) carbamoyloxy) group, 6- (N-phenyl-N- (2, 6-difluorophenyl) carbamoyloxy) hexyl, a group (N-phenyl-N- (2,3-dichlorophenyl) carbamoyloxy) methyl, a 2- (N-phenyl-N- (3,4-dichlorophenyl) -carbamoyloxy) ethyl group, a group 1- (N- phenyl-N- (3,5-dichlorophenyl) carbamoyloxy) ethyl, a 3- (N-phenyl-N- (2,4-dichlorophenyl) carbamoyloxy) propyl group, a 4- (N-phenyl-N- (2 , 6-dichlorophenyl) carbamoyloxy) butyl, a 5- (N-phenyl-N- (3,, 5-trifluorophenyl) -carbamoyloxy) pentyl group, a 6- (N-phenyl-N- (3,4,5) group -trichlorophenyl) carbamoyloxy) hexyl, a group (N-phenyl-N- (2,4,6-trifluorophenyl) carbamoyloxy) methyl, a group 2- (N-phenyl-N- (2,4,6-trichlorophenyl) carbamoyloxy) ethyl, a 1- (N-phenyl-N- (2-methylphenyl) -carbamoyloxy) ethyl group, a 3- (N-phenyl-) group N- (3-methylphenyl) carbamoyloxy) propyl, a 4- (N-phenyl-N- (4-methylphenyl) carbamoyloxy) butyl group, a 5- (N-phenyl-N- (2-methyl-3-chlorophenyl) group ) carbamoyloxy) pentyl, a 6- (N-phenyl-N- (3-methyl-4-chlorophenyl) -carbamoyloxy) hexyl group, a group (N-phenyl-N- (2-chloro-4-methylphenyl) carbamoyloxy) methyl, a group (N-phenyl-N- (2-methyl-3-fluorophenyl) carbamoyloxy) methyl, a 2- (N-phenyl-N- (2-trifluoromethylphenyl) -carbamoyloxy) ethyl group, a group 1- ( N-phenyl- N- (3-trifluoromethylphenyl) carbamoyloxy) ethyl, 3- (N- phenyl-N- (4-trifluoromethylphenyl) carbamoyloxy) propyl group, un-isopropilfenilcarbamoiloximetilo 2 isopropilfenilcarbamoiloximetilo 3-group, a group, a 4 - isopropylphenylcarbamoyloxymethyl, a 2-tert-butylphenylcarbamoyloxymethyl group, a 4-n-butylphenylcarbamoyloxymethyl group, a 2-methyl-4-chlorophenylcarbamoyloxymethyl group iloGroup, 3-tert-butilfenilcarbamoiloximetilo group, 4-tert-butilfenilcarbamoiloximetilo a-sec-butilfenilcarbamoiloximetilo 2 group, a 3-sec-butilfenilcarbamoiloximetilo group, 4-sec-butilfenilcarbamoiloximetilo group, a 4-pentilfenilcarbamoiloximetilo group, 4 hexylphenylcarbamoyloxymethyl, a 3,4-dimethoxyphenylcarbamoyloxymethyl group, a 3,4,5-trimethoxyphenylcarbamoyloxymethyl group, a 2-methoxyphenylcarbamoyloxymethyl group, a 3-methoxyphenylcarbamoyloxymethyl group, a 4-methoxyphenylcarbamoyloxymethyl group, a 2-methoxy-3-chlorophenylcarbamoyloxymethyl group, a 2- (2-fluoro-3-methoxyphenylcarbamoyloxy) ethyl group, a 1- (2-fluoro-4-methoxyphenylcarbamoyloxy) ethyl group, a 3- (2,6-dimethoxyphenylcarbamoyloxy) propyl group, a 4- (2, 3) group 4 trifluorofenilcarbamoiloxi) butyl, a pentyl group 5- (3, 4, 5 trifluorofenilcarbamoiloxi) group, 6- (2 trifluorometoxifenilcarbamoiloxi) hexyl group, a 3 trifluorometoxifenilcarbamoiloximetilo, trifluoromethoxy group, 4 fenilcarbamoiloximetilo group, 2- (4 trifluorometoxifenilcarbamoiloxi) ethyl group, 2- (N-methyl N- (4-trifluoromethoxyphenyl) carbamoyloxy) ethyl group, a 3 trifluorometilfenilcarbamoiloximetilo group, a 4 trifluorometilfenilcarbamoiloximetilo a clorofenilcarbamoiloximetilo 3-trifluoromethyl-4-group , a 3,5-ditrifluoromethoxyphenylcarbamoyloxymethyl group, a 2,4-dichlorophenylcarbamoyloxymethyl group, a 2-chlorophenylcarbamoyloxymethyl group, a 3-chlorophenylcarbamoyloxymethyl group, a 4-chlorophenylcarbamoyloxymethyl group, a 3,5-dichlorophenylcarbamoyloxymethyl group, a 3,4-dichlorophenylcarbamoyloxymethyl group 2-fluorofenilcarbamoiloximetilo fluorofenilcarbamoiloximetilo 3-4-pentafluoroetoxifenilcarbamoiloximetilo a group, a group, a 4- fluorofenilcarbamoiloximetilo group, 2- pentafluoroetoxifenilcarbamoiloximetilo, a 3- pentafluoroetoxifenilcarbamoiloximetilo, a group, a 2- isopropoxifenilcarbamoiloximetilo, a 3- isopropoxifenilcarbamoiloximetilo, a 4-isopropoxifenilcarbamoiloximetilo a-butoxifenilcarbamoiloximetilo 2 tert-metoxifenilcarbamoiloximetilo 3-metoxifenilcarbamoiloximetilo 4-etoxifenilcarbamoiloximetilo 4-group, a 4-n-butoxifenilcarbamoiloximetilo, a group, a group, a group, un-tert-butoxifenilcarbamoiloximetilo 3 group, 4-tert-butoxyphenylcarbamoyloxymethyl, a 2-sec-butoxyphenylcarbamoyloxymethyl group, a 3-sec-butoxyphenylcarbamoyloxymethyl group, a 4-sec-butoxyphenylcarbamoyloxymethyl group, a 2-n-heptafluoropropoxyphenylcarbamoyloxymethyl group, a 3-n-heptafluoropropoxyphenylcarbamoyloxymethyl group, a 4- group n-heptafluoropropoxyphenylcarbamoyloxymethyl, a 4-n-pentyloxyphenylcarbamoyloxymethyl group, a 4-n-hexyloxyphenylcarbamoyloxymethyl group, a 4-cyanophenylcarbamoyloxymethyl group, a (N-methyl-N- (3-cyanophenyl) carbamoyloxy) methyl group, a 2-cyano-phenylcarbamoyloxymethyl group, a 3,4-dicyanophenylcarbamoyloxymethyl group, a 3,4,5-tricityphenylcarbamoyloxymethyl group, a group 4- fenoxifenilcarbamoiloximetilo, a group (N-methyl-N- (3- phenoxyphenyl) carbamoyloxy) methyl group, 2- fenoxifenilcarbamoiloximetilo, a group 3,4- difenoxifenilcarbamoiloximetilo group, a 2,4,6-trifenoxifenilcarbamoiloximetilo a metiltiofenilcarbamoiloximetilo group, a group (N-methyl-N- (4-methylthiophenyl) carbamoyloxy) methyl group, a 3-metiltiofenilcarbamoiloximetilo a metiltiofenilcarbamoiloximetilo group 2, a 3,4 dimetiltiofenilcarbamoiloximetilo group, a 2,4,6 trimetiltiofenilcarbamoiloximetilo group, a 4 acetilfenilcarbamoiloximetilo, a 3-acetilfenilcarbamoiloximetilo a group acetilfenilcarbamoiloximetilo 2 ín 3,4-diacetilfenilcarbamoiloximetilo, a group (N-methyl-N- (3, 4-diacetylphenyl) carbamoyloxy) methyl group, a 2,4,6-triacetilfenilcarbamoiloximetilo a 4-biphenylcarbamoyloxymethyl group, a 3-biphenylcarbamoyloxymethyl group, a 2-biphenylcarbamoyloxymethyl group, a group (N-methyl-N- (2-biphenyl) carbamoyloxy) ethyl, a 3,4-diphenyl group rbamoyloxymethylA 2,4,6-trifenilfenilcarbamoiloximetilo group, a 4-n- heptiloxifenilcarbamoiloximetilo, a group (N-methyl-N-4- (n- heptyloxyphenyl) carbamoyloxy) methyl group, a 3-n- octiloxifenilcarbamoiloximetilo group, 2 -n- noniloxifenilcarbamoiloximetilo, a 4-n- deciloxifenilcarbamoiloximetilo, a 2,4-di-n-heptiloxifenilcarbamoiloximetilo group, a 2,4,6-tri-n-heptiloxifenilcarbamoiloximetilo, 4- (1, 1- dicloroheptiloxi) group fenilcarbamoiloximetilo group, a 4 bencilfenilcarbamoiloximetilo, a group (N-methyl-N- (4 benzylphenyl) carbamoyloxy) methyl group, a 3-bencilfenilcarbamoiloximetilo group, a 2-bencilfenilcarbamoiloximetilo, a 2,4-dibencilfenilcarbamoiloximetilo, a 2,4, 6-tribencilfenilcarbamoiloximetilo group, a 4-n-octilfenilcarbamoiloximetilo, a group (N-methyl-N- (4-n-octylphenyl) carbamoyloxy) methyl group, a 3-n-heptilfenilcarbamoiloximetilo group, 2-n-octilfenilcarbamoiloximetilo, a group 3- (8,8,8-trifluorooctyl) phenylcarbamoyloxymethi it, a 4-n-nonylphenylcarbamoyloxymethyl group, a 3-n-decylphenylcarbamoyloxymethyl group, a 2,4-di-n-octylphenylcarbamoyloxymethyl group, a 2,4,6-tri-n-octyldiphenylcarbamoyloxymethyl group, a 4-phenyl- 3-clorofenilcarbamoiloximetilo, a 4-phenoxy-3-metiltiofenilcarbamoiloximetilo group, a 4-n-heptyloxy-3- trifluorometoxifenilcarbamoiloximetilo group, a 4-n-octyl-2- trifluoromethylphenyl-carbamoyloxymethyl group, a 4-benzyl-2-metilfenilcarbamoiloximetilo, 3,4- etilendioxifenilcarbamoiloximetilo group, a 3,4-metilendioxifenilcarbamoiloximetilo a bencilcarbamoiloximetilo group, a 2-feniletilcarbamoiloximetilo a ciclohexilcarbamoiloximetilo group, a 1-naftilcarbamoiloxi ethyl group, a 2-naftilcarbamoiloximetilo group, 5- (2, 3-dihydro-lH-indenyl) carbamoyloxymethyl, a 5- (2,3-dihydrobenzofuryl) carbamoyloxymethyl group, a group (N-methyl-N- (3,4-methylenedioxyphenyl) carbamoyloxy) methyl, a group (N-methyl-N-benzylcarbamoyloxy) methyl, a group (N-methyl-N- (2-phenylethyl) carbamoyloxy) methyl, a group (N-methyl-N-cyclohexylcarbamoyloxy) methyl, a group (N-methyl-N- (1-naphthyl) carbamoyloxy) methyl, a group (N-methyl-N- (2-naphthyl) carbamoyloxy) methyl, a group (N-methyl-N- (5- (2,3-dihydro-lH-indenyl)) - carbamoyloxy) methyl, and a group (N-methyl-N- (2,3-dihydro-5-benzofuryl) carbamoyloxy) methyl (wherein, in the amino group, 1 or 2 groups selected from the following groups can be substituted: a C1-C6 alkyl group, the C1-C6 alkyl group phenyl described above, the C3-C8 cycloalkyl group described above, group naphthyl, group 2, 3-dihydro-lH-indenyl, group 2, 3-dihydrobenzofuryl, and the phenyl group described above [wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consists of a C1-C4 alkylenedioxy group, a cyano group, a phenoxy group, a C1-C6 alkylthio group, a C1-C6 alkanoyl group, a phenyl group, a C1-C6 alkyl group phenyl, a halogen atom, a C1-C10 alkyl group substituted or unsubstituted with halogen, and an alkoxy Cl-ClO group substituted or unsubstituted with halogen can be substituted (in a case where the substituent is a C1-C4 alkylenedioxy group, 1 or 2 groups are preferably substituted))). Examples of the C1-C6 alkyl group substituted with C1-C6 alkanoyl can include an acetylmethyl group, a 2-propionylethyl group, a 1-butyrylethyl group, a 2-acetylethyl group, a 3-acetylpropyl group, a 4-acetylbutyl group, a 4-isobutyrylbutyl group, a 5-pentanoylpentyl group, a 6-acetylhexyl group, a 6-tert-butylcarbonylhexyl group, a 1, 1-dimethyl-2-hexanoylethyl group, and a 2-methyl-3-acetylpropyl group. In addition to the C1-C6 alkyl phenoxy group described above (wherein, in the phenyl ring at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group -C6 substituted or unsubstituted with halogen can be substituted), examples of the C1-C6 alkyl phenoxy group (wherein, in the phenyl ring, at least one selected from the following groups can be substituted: a halogen atom; an alkylenedioxy group C1-C4, a C1-C4 alkoxycarbonyl group, a phenyl group, a phenoxy group, a pyrrolyl group, a benzothiozolyl group, a 1,2,4-triazolyl group, an imidazolyl group, an isoxazolyl group, a benzoxazolyl group; benzotriazolyl group, a cyano group, a nitro group, a C2-C6 alkenyl group, a C1-C6 alkanoyl group, a C1-C6 alkyl group substituted with C1-C6 alkoxycarbonyl, a C1-C6 alkyl group substituted with C1-C6 alkanoyl a group -N (R11B) R12B (wherein R11B and R12 B, which may be identical or different, each represents a hydrogen atom, a C1-C6 alkyl group, a C1-C6 alkanoyl group, or a phenyl group, and R11B and R12B may link to each other adjacent to it directly or through a nitrogen, oxygen or sulfur atom, in order to thereby form a 5-7 membered saturated heterocyclic ring together with the nitrogen atom, wherein, in the heterocyclic ring, at least one selected from the group consisting of a C 1 -C 6 alkoxycarbonyl group and an amino group [wherein, in the amino group, at least one selected from a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted) and a Cl-Cß alkyl group can be substituted] can be substituted); a Cl-Cβ phenyl alkoxy group; an alkyl Cl-Cβ phenyl group; an alkylthio Cl-Cß group; a C3-C8 cycloalkyl group; a Cl-Cß alkyl group substituted or unsubstituted with halogen; and a C1-Cβ alkoxy group substituted or unsubstituted with halogen), May further include alkyl phenoxy Cl-Css such as 3,4-metilendioxifenoximetilo group, a 3,4-etilendioxifenoximetilo group, a 4-etoxicarbonilfenoximetilo group, a 3-metoxicarbonilfenoximetilo group, a 2-etoxicarbonilfenoximetilo, a 2, 4-dietoxicarbonilfenoximetilo a 2,4,6-trietoxicarbonilfenoximetilo metilfenoximetilo 2-ethoxycarbonyl-4-metoxifenoximetilo 2-methoxycarbonyl-4-group, a group, a group, a-methoxycarbonyl-3-metoxifenoximetilo 2 group, a 2- (4 -ethoxycarbonylphenoxy) ethyl, a 4-cyanophenoxymethyl group, a 3-cyanophenoxymethyl group, a 2-cyanophenoxymethyl group, a 2,4-dicyanophenoxymethyl group, a 2, 4,6-tricarophenoxymethyl group, a 2- (4-cyanophenoxy) group ethyl, a 4-nitrophenoxymethyl group, a 3-nitrophenoxymethyl group, a 2-nitrophenoxymethyl group, a 2,4-dinitrophenoxymethyl group, a 2,4,6-trinitrophenoxymethyl group, a 2- (4-nitrophenoxy) ethyl group, a 4-allylphenoxymethyl group, a 3-allylphenoxymethyl group, a 2-allylphene group ximethyl, a 3, 4-diallylphenoxymethyl group, a 3, 4, 5-triallylphenoxymethyl group, a 2- (4-allylphenoxy) ethyl group, a 2- (3-allylphenoxy) ethyl group, a 3-diethylaminophenoxymethyl group, a group 3-anilinophenoxymethyl, a 4-acetylaminophenoxymethyl group, a 2,4,6-tri (diethylamino) phenoxymethyl group, a 2-anilinophenoxymethyl group, a 2,4-diacetylaminophenoxymethyl group, a 2- (3-diethylaminophenoxy) ethyl group, a 2- (3-anilinophenoxy) ethyl group, a 2- (4- (2-acetylethyl) phenoxy) ethyl group, a 4- (2-acetylethyl) phenoxymethyl group, a 3-acetylmethylphenoxymethyl group, a 2- (3-) group acetilpropil) phenoxymethyl, 6-tri (2-acetylethyl) phenoxymethyl group, a 4-metoxicarbonilmetilfenoximetilo group, a 3-etoxicarbonilmetilfenoximetilo, a group 2- di 4-group 2, (2-acetylethyl) phenoxymethyl group, a 2, 4, methoxycarbonylmethylphenoxymethyl, a 2,4-dimethoxycarbonylmethylphenoxymethyl group, a 2,4,6-trimethoxycarbonylmethylphenoxymethyl group, a 2- (4-methoxycarbonylmethylphenoxy) ethyl group, a upo 4-propionilfenoximetilo group, a 4-acetilfenoximetilo group, a 3-propionilfenoximetilo group, a 2-acetilfenoximetilo, a 2, 4-dipropionilfenoximetilo a 2,4,6-triacetilfenoximetilo group, a 2- (4-propionylphenoxy) group ethyl a-bencilfenoximetilo 2 bencilfenoximetilo 3-bencilfenoximetilo 4-5-tribencilfenoximetilo metiltiofenoximetilo four-group, a group, a 2,3-dibencilfenoximetilo group, 3, 4, a group, a 3-methylthiophenoxy ethyl , a 2-methylthiophenoxymethyl group, a 2,4-dimethylthiophenoxymethyl group, a 2,4,6-trimethylthiophenoxymethyl group, a 2- (4-methylthiophenoxy) ethyl group, a 4-cyclopentylphenoxymethyl group, a 3-cyclohexylphenoxymethyl group, a group 4-ciclohexilfenoximetilo cicloheptilfenoximetilo 2-cyclopentyl-6-ciclooctilfenoximetilo 4-, group, a 2,4-diciclopentilfenoximetilo group, a 2, a 2- (4-cyclohexylphenoxy) ethyl group, 2- (4-cyclopentylphenoxy) group ethyl, a 4-n-octyloxyphenoxymethyl group, a 2- (4-n-octyl) group xifenoxi) ethyl, a 4-phenylphenoxymethyl group, a 3-phenylphenoxymethyl group, a 2-phenylphenoxymethyl group, a 2,4-diphenylphenoxymethyl group, a 2,4,6-triphenylphenoxymethyl group, a 2- (4-phenylphenoxy) ethyl group , a 4-phenoxyphenoxymethyl group, a 3-phenoxyphenoxymethyl group, a 2-phenoxyphenoxymethyl group, a 2,4-diphenoxyphenoxymethyl group, a 2,4,6-trifenoxyphenoxymethyl group, a 2- (3-phenoxyphenoxy) ethyl group, a group 4-benzyloxyphenoxymethyl, a 3-benzyloxyphenoxymethyl group, a 2-benzyloxyphenoxymethyl group, a 2,4-dibenzyloxyphenoxymethyl group, a 2,4,6-tribenzyloxyphenoxymethyl group, a 2- (4-benzyloxyphenoxy) ethyl group, a 2, 4 group -dibenzylphenoxymethyl, a 2,4,6-tribenylphenoxymethyl group, a 2- (4-benzylphenoxy) ethyl group, a 4- (1-pyrrolyl) phenoxymethyl group, a 3- (l-pyrrolyl) phenoxymethyl group, a 2- group (1-pyrrolyl) phenoxymethyl, a 2,4-di (1-pyrrolyl) phenoxymethyl group, a 2,4,6-tri (1-pyrrolyl) phenoxymethyl group, a 2- (2-benzothiazole) phenoxymethyl group, a 2- (2-benzothiazolyl) phenoxymethyl group, a 3- (2-benzothiazolyl) phenoxymethyl group, a 2, 4, 6-tri (5-benzothiazolyl) phenoxymethyl group, a 2,4-di (6-benzothiazolyl) phenoxymethyl group, a 4- (11, 2) group , 4-triazolyl) phenoxymethyl, a 3- (ll, 2,4-triazolyl) phenoxymethyl group, a 2- (II, 2,4-triazolyl) phenoxymethyl group, a 4- (3-l, 2,4- triazolyl) phenoxymethyl, a 2 2,, 44-di (5-l, 2,4-triazolyl) phenoxymethyl group, a 2, 4,6-tri (1-1,2,4-triazolyl) phenoxymethyl group, a 4- (5-isoxazolyl) phenoxymethyl group, a 3- (3-isoxazolyl) phenoxymethyl group, a 2- (4-isoxazolyl) phenoxymethyl group, a 2- (5-isoxazolyl) phenoxymethyl group, a 2, 4-di group (5-isoxazolyl) phenoxymethyl, a 2, 4,6-tri (5-isoxazolyl) phenoxymethyl group, a 4- (1-imidazolyl) phenoxymethyl group, a 3- (2-imidazolyl) phenoxymethyl group, a 2- ( 4-imidazolyl) phenoxymethyl, a 2,4-di (1-imidazolyl) phenoxymethyl group, a 2,4,6-tri (1-imidazolyl) phenoxymethyl group, a 4- (l-benzotriazolyl) phenoxymethyl group, a group 3 - (l- benzotriazolyl) phenoxymeth ilo, a 2- (l-benzotriazolyl) phenoxymethyl group, a 2- (l-benzotriazolyl) phenoxymethyl group, a 2,4-di (l-benzotriazolyl) phenoxymethyl group, a 2, 4, 6-tri (1-) group benzotriazolyl) phenoxymethyl, a 4- (6-benzimidazolyl) phenoxymethyl group, a 3- (5-benzimidazolyl) phenoxymethyl group, a 2- (2-benzimidazolyl) phenoxymethyl group, a 2- (l-benzotriazolyl) phenoxymethyl group, a group 2,4-di (2-benzimidazolyl) phenoxymethyl, a 2, -4,6-Jtri (2-benzimidazolyl) phenoxymethyl group, a 1-4- (4-tert-butoxycarbonyl-1-piperazinyl) phenoxymethyl group, a 2- (4- (4- (4- (N- (4-chlorophenyl) -N-methylamino)) -1-piperidyl) phenoxy) ethyl group, a 2- (4- (1-1, 2, 4) group -triazolyl) phenoxy) ethyl, a 2- (2- (5-isoxazolyl) phenoxy) ethyl group, a 2- (2-methoxy-4-allylphenoxy) ethyl group, a 2- (2-fluoro-4-nitrophenoxy) group ) ethyl, a 2- (2-ethoxy-5-allylphenoxy) ethyl group, a 2-fluoro-4-nitrophenoxymethyl group, a 2-methoxy-4-allylphenoxymethyl group, a 2-ethoxy-5-allylphenoxymethyl group, and a 2-methyl-4-ace group tylphenoxymethyl (wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the following groups can be substituted: a halogen atom; the C1-C4 alkylenedioxy group described above; the C1-C6 alkoxycarbonyl group described above; a phenyl group; a phenoxy group; a pyrrolyl group; a benzothiozolyl group; a 1,2,4-triazolyl group; an imidazolyl group; an isoxazolyl group; a benzoxazolyl group; a benzotriazolyl group; a cyano group; a nitro group; the C2-C6 alkenyl group described above; the C1-C6 alkanoyl group described above; the C1-Cß alkyl group substituted with alkoxycarbonyl Cl-Cß described above; the Cl-Cß alkyl group substituted with Cl-Cß alkanoyl described above; a group -N (R11B) R12B (wherein R11B and R12B, which may be identical or different, each represents a hydrogen atom, the Cl-Cß alkyl group described above, the C1-Cβ alkanoyl group described above, or a phenyl group, and the R11B and R12B described above can be linked to each other adjacent to it directly or through a nitrogen, oxygen or sulfur atom, in order to form a 5-7 membered saturated heterocyclic ring together with the atom of nitrogen, wherein, in the heterocyclic ring, 1 to 3 groups selected from the group consisting of a C1-Cβ alkoxycarbonyl group and an amino group [wherein, in the amino group, 1 or 2 groups selected from a phenyl group ( wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group replaced or not replaced co halogen can be substituted) and a Cl-Cß alkyl group can be substituted] can be substituted); the Cl-Cβ phenyl alkoxy group described above; the Cl-Cβ phenyl alkyl group described above; the Cl-Cß alkylthio group described above; the C3-C8 cycloalkyl group described above; the Cl-Cß alkyl group substituted or unsubstituted with halogen described above; and the Cl-ClO alkoxy group substituted or unsubstituted with halogen described above (in a case where the substituent is a C1-C4 alkylenedioxy group, 1 or 2 groups can be substituted)). Examples of lo-C6 tetrahydropyranyloxy can be (2-tetrahydropyranyloxy) ethyl group, a 2- (3-tetrahydropyranyloxy) ethyl group, a l- (4-tetrahydropyranyloxy) ethyl group, a 2- (2-tetrahydropyranyloxy) ethyl group, a 3- (2-tetrahydropyranyloxy) propyl group, a 4- (2-tetrahydropyranyloxy) butyl group, a 4- (3-tetrahydropyranyloxy) butyl group, a 5- (2-tetrahydropyranyloxy) pentyl group, a 6- (2) group -tetrahydropyranyloxy) hexyl, a 6- (2-tetrahydropyranyloxy) hexyl group, a 1, 1-dimethyl-2- (4-tetrahydropyranyloxy) ethyl group, and a 2-methyl-3- (3-tetrahydropyranyloxy) propyl group. Examples of the Cl-Cß alkyl group substituted with Cl-Cβ alkylo furyl (wherein, in the furan ring, at least one C 1 -C 6 alkoxycarbonyl group can be substituted) can include C 1 -C 6 alkyl groups substituted with C 1 -C 6 alkoxy furyl such as a ((2-furyl) methoxy) methyl group, a (2- (3-furyl) ethoxy) ethyl group, a (3- (2-furyl) propoxy) methyl group, a group (2- (3- furyl) propoxy) methyl, a (4- (2-furyl) butoxy) methyl group, a (5- (3-furyl) pentoxy) methyl group, a (4- (2-furyl) pentoxy) methyl group, a group (ß- (3-furyl) hexyloxy) methyl, a 2- ((2-furyl) methoxy) ethyl group, a 1- (2- (3-furyl) ethoxy) ethyl group, a 3- (3- ( 2-furyl) propoxy) propyl, a 4- (2- (3-furyl) propoxy) butyl group, a 5- (4- (2-furyl) butoxy) hexyl group, a 1, 1-dimethyl-2- group (5- (3-furyl) pentoxy) ethyl, a 2-methyl-3- (4- (2-furyl) pentoxy) propyl group, a 2- (β- (3-furyl) hexyloxy) ethyl group, a group ((5-ethoxycarbonyl-2-furyl) methoxy) methyl, a group ((4-met oxycarbonyl-2-furyl) methoxy) methyl, a ((3-propoxycarbonyl-2-furyl) methoxy) methyl group, a ((5-butoxycarbonyl-2-furyl) methoxy) methyl group, a ((4-pentyloxycarbonyl- 2-furyl) methoxy) methyl, a ((3-hexyloxycarbonyl-2-furyl) methoxy) methyl group, a ((3,5-diethoxycarbonyl-2-furyl) methoxy) methyl group, and a group ((3,4 , 5-triethoxycarbonyl-2-furyl) ethoxy) methyl (wherein, in the furan ring, 1 to 3 alkoxycarbonyl Cl-Cß groups can be substituted). Examples of the C3-C8 cycloalkyl Cl-Cβ alkyl group may include a cyclohexylmethyl group, a 2-cyclopropylethyl group, a 1-cyclopentylethyl group, a 3-cyclobutylpropyl group, a 4-cyclohexylbutyl group, a 5- cycloheptylpentyl group, a 6-cyclooctylhexyl group, a 1, l-dimethyl-2-cyclohexylethyl group, and a 2-methyl-3-cyclohexylpropyl group. Examples of the Cl-Cß alkyl group substituted with Cl-Cβ tetrazolyl alkoxy (wherein, in the tetrazole ring, a group selected from the group consisting of the following groups can be substituted: a phenyl group (wherein, in the phenyl ring , at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), an alkyl Cl group -Cβ phenyl, and a Cl-Cβ C3-C8 cycloalkyl alkyl group), can include Cl-Cß alkyl groups substituted with Cl-Cβ tetrazolyl alkoxy such as a group ((5-tetrazolyl) methoxy) methyl, a group (2- (5-tetrazolyl) ethoxy) methyl, a group (3- (5-tetrazolyl) propoxy) ethyl, a (2- (5-tetrazolyl) propoxy) ethyl group, a (4- (5-tetrazolyl) butoxy) methyl group , vm. group (5- (5-tetrazolyl) entoxy) methyl, a group (4- (l-tetrazolyl) pentoxy) methyl, a group (β- (5-tetrazolyl) exoxy) methyl, a group (2- (1-tetrazolyl) ) methoxy) ethyl, an l- (2- (5-tetrazolyl) ethoxy) ethyl group, a 3- (3- (l-tetrazolyl) propoxy) propyl group, a 4- (2- (5-tetrazolyl) propoxy group butyl, a 5- (4- (l-tetrazolyl) butoxy) hexyl group, a 1, l-dimethyl-2- (5- (5-tetrazolyl) pentoxy) ethyl group, a 2-methyl-3- ( 4- (1-tetrazolyl) pentoxy) propyl, a 2- (6- (5-tetrazolyl) hexyloxy) ethyl group, a ((1- (2-phenylethyl) -5-tetrazolyl) methoxy) methyl group, a group ( (l-cyclohexylmethyl-5-tetrazolyl) methoxy) methyl, a group ((5-benzyl-l-tetrazolyl) methoxy) methyl, a ((1-cyclopentylmethyl-5-tetrazolyl) methoxy) ethyl group, (5 - (2-cyclohexylethyl) -1-tetrazolyl) methoxy) methyl, a ((1-benzyl-5-tetrazolyl) methoxy) methyl group, a ((1-cycloheptylmethyl-5-tetrazolyl) methoxy) methyl group, a group ( (1- (3-phenylpropyl) -5-tetrazolyl) methoxy) methyl, a group (l-phen il-5-tetrazolyl) methoxymethyl, a ((1- (4-trifluoromethoxyphenyl) -5-tetrazolyl) methoxymethyl group, a group ((1- (4-trifluoromethylphenyl) -5-tetrazolyl) methoxy) methyl, a ((1- (4-chlorophenyl) -5-tetrazolyl) methoxy) methyl group (wherein, in the tetrazole ring, a group selected from A group consisting of the following groups can be substituted: a phenyl group (wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a straight alkyl group or branched substituted or unsubstituted with halogen containing 1 to 6 carbon atoms, and a straight or branched alkoxy group substituted or unsubstituted with halogen containing 1 to 6 carbon atoms, can be substituted), the alkyl group Cl-Cβ phenyl described above, and the C3-C8 cycloalkyl C1-C3 alkyl group described above). Examples of the Cl-Cß alkyl group substituted with Cl-Cβ isoxazolyl alkoxy (wherein, in the isoxazole ring, at least one Cl-Cß alkyl group can be substituted) can include Cl-Cβ alkyl substituted with Cl-Cβ isoxazolyl alkoxy such as a group ((3-isoxazolyl) methoxy) methyl, a (2- (4-isoxazolyl) ethoxy) ethyl group, a (3- (5-isoxazolyl) propoxy) ethyl group, a (2- (3-isoxazolyl) group ) propoxy) methyl, a (4- (4-isoxazolyl) butoxy) methyl group, a (5- (5-isoxazolyl) pentoxy) methyl group, a (4- (3-isoxazolyl) pentoxyl) methyl group, a group ( 6- (4-isoxazolyl) hexyloxy) methyl, a (2- (5-isoxazolyl) methoxy) ethyl group, n group 1- (2- (3-isoxazolyl) ethoxy) ethyl, a group 3 - (3- (4-isoxazolyl) propoxy) propyl, a 4- (2- (5-isoxazolyl) propoxy) butyl group, a 5- (4- (3-isoxazolyl) butoxy) hexyl group, a 1, 1-dimethyl group -2- (5- (4-isoxazolyl) pentoxy) ethyl, a 2-methyl-3- (4- (5-isoxazolyl) pentoxy) propyl group, a 2- (6- (3-isoxazolyl) hexyloxy) ethyl group , a group ( ( 5-methyl-3-isoxazolyl) methoxy) methyl, a ((4-ethyl-3-isoxazolyl) ethoxy) methyl group, a ((3-n-propyl-4-isoxazolyl) methoxy) methyl group, a qgrruuppoo (( 5-n-butyl-3-isoxazolyl) methoxy) methyl, a ((4-n-pentyl-3-isoxazolyl) methoxy) methyl group, a ((3-n-hexyl-5-isoxazolyl) methoxy) methyl group, a ((4,5-dimethyl-3-isoxazolyl) methoxy) methyl group (wherein, in the isoxazole ring, the C 1 -C 6 alkyl groups to 2 described above can be substituted). Examples of the C1-C6 alkyl group substituted with Cl-Cβ benzothienyl alkoxy (wherein, in the benzothiophene ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen , and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can include C 1 -C 6 alkyl groups substituted with C 1 -C 6 alkoxy benzothienyl such as a ((3-benzothienyl) ethoxy) methyl group, a group (( 2-benzothienyl) ethoxy) methyl, a (3- (4-benzothienyl) propoxy) methyl group, a (2- (5-benzothienyl) ropoxy) methyl group, a (4- (6-benzothienyl) butoxy) ethyl group, a group (5- (7-benzothienyl) pentoxy) methyl, a group (4- (3-benzothienyl) pentoxy) methyl, a group (6- (2-benzothienyl) hexyloxy) methyl, a group 2 - ((4- benzothienyl) methoxy) ethyl, an l- (2- (5-benzothienyl) ethoxy) ethyl group, a 3- (3- (6-benzothienyl) propoxy) propyl group, a 4- (2- (7-benzothienyl) group) propoxy) butyl, a 5- (4- (3-benzothie) group nyl) butoxy) hexyl, a 1, l-dimethyl-2- (5- (3-benzothienyl) pentoxy) ethyl group, a 2-methyl-3- (4- (5-benzothienyl) pentoxy) propyl group, a group 2- (6- (3-benzothienyl) hexyloxy) ethyl, a ((5-methyl-3-benzothienyl) methoxy) methyl group, a ((4-ethyl-3-benzothienyl) methoxy) methyl group, a group (( 5-chloro-3-benzothienyl) methoxy) ethyl, a ((6-methyl-3-benzothienyl) methoxy) methyl group, a ((4-trifluoromethyl-3-benzothienyl) methoxy) methyl group, a group ((3- methoxy-5-benzothienyl) methoxy) methyl, a ((5-trifluoromethoxy-3-benzothienyl) methoxy) methyl group, a ((4,5-dichloro-3-benzothienyl) methoxy) methyl group, a group ((2, 4,5-trifluoro-3-benzothienyl) methoxy) methyl, a group ((4,5-dichloro-2-methyl-3-benzothienyl) methoxy) methyl, and a group ((4,5-dichloro-2-methoxy) 3-benzothienyl) methoxy) methyl (wherein, in the benzothiophene ring, 1 to 3 groups selected from the group consisting of the halogen atom described above, the C1-C6 alkyl group substituted or unsubstituted with halogen above, and the C1-C6 alkoxy group substituted or unsubstituted with halogen described above may be substituted).

Examples of the C1-C6 alkyl group substituted with C1-C6 alkoxy 1,3,4-oxadiazolyl (wherein, in the 1,3,4-oxadiazole ring, a phenyl group can be substituted [where, in the phenyl ring , at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted]) can include alkyl groups C1-C6 substituted with C1-C6 alkoxy 1,3,4-oxadiazolyl such as a group ((2-1, 3, 4-oxadiazolyl) methoxy) methyl, a group (2- (2-1, 3, 4- oxadiazolyl) ethoxy) methyl, a group (3- (2-1, 3,4-oxadiazolyl) propoxy) methyl, a group (2- (2-l, 3,4-oxadiazolyl) propoxy) methyl, a group (4 - (2-l, 3,4-oxadiazolyl) butoxy) methyl, a group (5- (2-l, 3,4-oxadiazolyl) pentoxy) methyl, a group (4- (2-l, 3,4- oxadiazolyl) pentoxy) methyl, a group (6- (2-l, 3,4-oxadiazolyl) hexyloxy) methyl, a group 2 - ((2-l, 3,4-oxadiazolyl) methoxy) ethyl, a group I - (2- (2-l, 3,4-oxadiazolyl) ethoxy) ethyl, a 3- (3- (2-l, 3,4-oxadiazolyl) propoxy) propyl group, a 4- (2- (2 -l, 3,4-oxadiazolyl) propoxy) butyl, a group 5 - ((2-l, 3,4-oxadiazolyl) methoxy) pentyl, a group 6- (4- (2-l, 3,4-oxadiazolyl ) butoxy) hexyl, a 1, l-dimethyl-2- (5- (2- 1, 3, 4-oxadiazolyl) pentoxy) ethyl group, a 2-methyl-3- (4- (2-1, 3) group , 4-oxadiazolyl) pentoxy) propyl, a 2- (6- (2-1, 3, 4-oxadiazolyl) hexyloxy) ethyl group, a group (5- (4-methylphenyl) -2- 1, 3, 4- oxadiazolyl) methoxymethyl, a group (5- (4-chlorophenyl) -2- 1, 3, 4-oxadiazolyl) methoxymethyl, a group (5- (4-trifluoromethylphenyl) -2-1, 3,4-oxadiazolyl) methoxymethyl, a group (5- (4-methoxyphenyl) -2-1, 3, 4-oxadiazolyl) methoxymethyl, a group (5- (4-trifluoromethoxyphenyl) -2,1,4,4-oxadiazolyl) methoxymethyl, a group (5 - (2,4-dichlorophenyl) -2- 1, 3, -oxadiazolyl) methoxymethyl, a group (5- (2,4,6-trimethylphenyl) -2-1, 3,4-oxadiazolyl) methoxymethyl, and a group (5- (2,4-dimethoxyphenyl) -2-1, 3, 4-oxadiazolyl) meto ximethyl (wherein, in the 1,3,4-oxadiazole ring, the phenyl group described above can be substituted [wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted]). Examples of the C1-C6 alkyl group substituted with C2-C6 alkynyloxy can include an ethynyloxymethyl group, a 2-ethynyloxymethyl group, a 2- (2-ethynyloxy) ethyl group, a 1- (2-butynyloxy) ethyl group, a group 2- (3-Butynyloxy) ethyl, a 3- (1-methyl-2-propynyloxy) propyl group, a 4- (2-pentynyloxy) butyl group, a 4- (2-hexynyloxy) butyl group, a 5- group (2-propynyloxy) pentyl, a 6- (2-propynyloxy) hexyl group, a 6- (2-butynyloxy) hexyl group, a 1, 1-dimethyl-2- (2-propynyloxy) ethyl group, and a 2 group -methyl-3- (2-propynyloxy) propyl. Examples of the C 1 -C 6 alkyl group substituted with C 1 -C 6 alkoxy naphthyl may include a (1-naphthyl) methoxymethyl group, a (2- (2-naphthyl) ethoxy) methyl group, a (3- (1-naphthyl) group propoxy) methyl, a (2- (2-naphthyl) propoxy) methyl group, a (4- (1-naphthyl) butoxy) methyl group, a (5- (2-naphthyl) pentoxy) methyl group, a group (4) - (l-naphthyl) pentoxy) methyl, a (6- (1-naphthyl) hexyloxy) methyl group, a 2- ((1-naphthyl) methoxy) ethyl group, an l- (2- (2-naphthyl) group ethoxy) ethyl, a 3- (3- (1-naphthyl) propoxy) propyl group, a 4- (2- (2-naphthyl) propoxy) butyl group, a 5- (4- (l-naphthyl) butoxy) group pentyl, a 6- (5- (2-naphthyl) pentoxy) hexyl group, a 1, l-dimethyl-2- (4- (1-naphthyl) pentoxy) ethyl group, and a 2-methyl-3- group ( 6- (1-naphthyl) hexyloxy) propyl. Examples of the C1-C6 alkyl group substituted with C1-C6 alkoxy 1,2,4-oxadiazolyl [wherein, in the 1,2,4-oxadiazole ring, a phenyl group may be substituted] may include C1-C6 alkyl groups substituted with C 1 -C 6 alkoxy 1,2,4-oxadiazolyl such as a group ((3-1, 2,4-oxadiazolyl) methoxy) methyl, a (2- (5-l, 2,4-oxadiazolyl) ethoxy) methyl group, a (3- (3-l, 2,4-oxadiazolyl) propoxy) methyl group , a group (2- (5-l, 2,4-oxadiazolyl) propoxy) methyl, a group (4- (3-l, 2,4-oxadiazolyl) butoxy) methyl, a group (5- (5-l) , 2,4-oxadiazolyl) pentoxy) methyl, a group (4- (3-l, 2,4-oxadiazolyl) pentoxy) methyl, a group (6- (3-1,2,4-oxadiazolyl) hexyloxy) methyl , a 2 - ((5-l, 2,4-oxadiazolyl) methoxy) ethyl group, a 1-l- (2- (3-l, 2,4-oxadiazolyl) ethoxy) ethyl group, a 3- (3) group - (5-1, 2, 4-oxadiazolyl) propoxy) propyl, a 4- (2- (3-1,2,4-oxadiazolyl) propoxy) butyl group, a group 5- ((3-1.2, 4-oxadiazolyl) methoxy) pentyl, an 6- (4- (5-1,2,4-oxadiazolyl) butoxy) hexyl group, a 1,1-dimethyl-2- (5- (3-1.2, 4-oxadiazolyl) pentoxy) ethyl, a 2-methyl-3- (4- (5-1,2,4-oxadiazolyl) pentoxy) propyl group, a 2- (6- (3-1, 2, 4- oxadiazolyl) hexyloxy) ethyl, a group (5-phenyl-3-1,2,4-oxadiazolyl) methoxymethyl, and a group (3-phenyl-5-1,2,4-oxad) iazolyl) methoxymethyl [wherein, in the 1,2,4-oxadiazole ring, a phenyl group can be substituted]. Examples of the Cl-Cß alkyl group substituted with Cl-Cβ pyridyl alkoxy [wherein, in the pyridine ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen , and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] can include Cl-Cß alkyl groups substituted with Cl-Cβ pyridyl alkoxy such as a (2-pyridyl) methoxymethyl group, a group (2- (3 -pyridyl) ethoxy) methyl, a (3- (4-pyridyl) propoxy) methyl group, a (2- (2-pyridyl) propoxy) methyl group, a (4- (3-pyridyl) butoxy) methyl group, a (5- (4-pyridyl) pentoxy) methyl group, a (4- (2-pyridyl) pentoxy) methyl group, a (6- (3-pyridyl) hexyloxy) methyl group, a (2- (4-pyridyl) group ) methoxy) ethyl, a 1- (2- (2-pyridyl) ethoxy) ethyl group, a 3- (3- (3-pyridyl) propoxy) propyl group, a 4- (2- (4-pyridyl) propoxy group butyl, a 5- ((2-pyridyl) methoxy) pentyl group, a 6- (4- (2-p) group iridyl) butoxy) hexyl, a 1,1-dimethyl-2- (5- (3-pyridyl) pentoxy) ethyl group, a 2-methyl-3- (4- (4-pyridyl) pentoxy) propyl group, a group 2- (6- (2-pyridyl) hexyloxy) ethyl, a group (2-trifluoromethyl-5-pyridyl) methoxymethyl, a group (4-chloro-2-pyridyl) methoxymethyl, a group (3-trif luoromethyl-2) pyridyl) ethoxymethyl, a (2-methoxy-4-pyridyl) methoxymethyl group, a (2-trifluoromethoxy-5-pyridyl) methoxymethyl group, a (2,4-dibromo-3-pyridyl) ethoxymethyl group, a group ( 2, 4, 6-trimethyl-5-pyridyl) methoxymethyl, a (2,4-dimethoxy-5-pyridyl) methoxymethyl group, and a (2,4,6-trifluoro-3-pyridyl) methoxymethyl group [wherein, in the pyridine ring, 1 to 3 groups selected from the group consisting of the halogen atom described above, the substituted or unsubstituted C1-C6 alkyl group with halogen described above, and the substituted or unsubstituted C1-C6 alkoxy group with halogen described above can be replaced]. Examples of the C1-C6 alkyl group substituted with C1-C6 alkoxy thiazolyl [wherein, in the thiazole ring, at least one selected from the group consisting of a phenyl group (wherein, in the phenyl ring, at least one selected from group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) and a lower alkyl group can be substituted], can include C 1 -C 6 alkyl groups substituted with C 1 -C 6 alkoxy thiazolyl such as a (4-thiazolyl) methoxymethyl group, a (2- (2-thiazolyl) ethoxy) methyl group, a (3- (5-thiazolyl) propoxy group) methyl, a (2- (4-thiazolyl) propoxy) methyl group, a (4- (2-thiazolyl) butoxy) methyl group, a (5- (4-thiazolyl) pentoxy) methyl group, a group (4- ( 5-thiazolyl) pentoxy) methyl, a group (6- (4-thiazolyl) hexyloxy) methyl, a group (2- (2-thiazolyl) methoxy) ethyl, a group 1- (2- (5-thiazolyl) ethoxy) ethyl, a 3- (3- (4-thiazolyl) propoxy) propyl group, a 4- (2- (2-thiazolyl) propoxy) butyl group, a 5- ((4-thiazolyl) methoxy) pentyl group, a group 6 - (4- (5-thiazolyl) butoxy) hexyl, a 1, l-dimethyl-2- (5- (4-thiazolyl) pentoxy) ethyl group, a 2-methyl-3- (4- (2-thiazolyl) group ) pentoxy) propyl, a 2- (6- (5-thiazolyl) hexyloxy) ethyl group, a (2- (4-methylphenyl) -4-thiazolyl) ethoxymethyl group, a (2- (4-chlorophenyl) -4- group -thiazolyl) methoxymethyl, a group (2- (4-trifluoromethylphenyl) -4-thiazolyl) methoxymethyl, a group (5- (4-methoxyphenyl) -4-thiazolyl) methoxymethyl, a group (2- (4-trifluoromethoxyphenyl) - 4-thiazolyl) methoxymethyl, a group (5- (2,4-dichlorophenyl) -2- thiazolyl) methoxymethyl, a (4- (2,4-, 6-trimethylphenyl) -2- thiazolyl) ethoxymethyl group, a group (4) - (2,4-dimethoxyphenyl) -2-thiazolyl) methoxymethyl, a (2-methyl-4-thiazolyl) methoxymethyl group, a (2,5-dimethyl-5-thiazolyl) methoxymethyl group, and a (2-phenyl) group -4-methyl-5-thiazolyl) methoxymethyl [wherein, in the thiazole ring, 1 or 2 groups selected from the group consisting of the phenyl group described above (wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C1-C6 alkyl group straight or branched substituted or unsubstituted with halogen containing 1 to 6 carbon atoms, and a straight or branched C 1 -C 6 alkoxy group substituted or unsubstituted with halogen containing 1 to 6 carbon atoms, can be substituted) and a group straight or branched alkyl containing 1 to 6 carbon atoms can be substituted]. Examples of the Cl-Cß alkyl group substituted with Cl-Cβ 1, 2, 3, 4-tetrahydronaphthyl alkoxy [wherein, in the 1, 2, 3, 4-tetrahydronaphthalene ring, at least one Cl-Cß alkyl group can be substituted] may include Cl-Cß alkyl groups substituted with 1, 2, 3, 4-tetrahydronaphthyl C1-C6 alkoxy groups such as a group (6-1, 2, 3, 4-tetrahydronaphthyl) methoxymethyl, a group (2- (2 -1, 2, 3, 4-tetrahydronaphthyl) ethoxy) methyl, a group (3- (3-1, 2, 3, 4-tetrahydronaphthyl) propoxy) methyl, a group (2- (4-1, 2, 3 , 4-tetrahydronaphthyl) propoxy) methyl, a group (4- (5-1, 2, 3, 4-tetrahydronaphthyl) butoxy) methyl, a group (5- (6- 1, 2, 3, 4-tetrahydronaphthyl) pentoxy ) methyl, a group (4- (6- 1, 2, 3, 4-tetrahydronaphthyl) pentoxy) methyl, a group (6- (5- 1, 2, 3, 4-tetrahydronaphthyl) hexyloxy) methyl, a group 2 - ((6- 1, 2, 3, 4-tetrahydronaphthyl) methoxy) ethyl, an l- (2- (6- 1, 2, 3, 4-tetrahydronaphthyl) ethoxy) ethyl group, a 3- (3-) group (5- 1, 2, 3, 4-tetrahydronaphthyl) propoxy) propyl, a group 4 - (2- (5- 1, 2, 3, 4-tetrahydronaphthyl) propoxy) butyl, a 5- (4- (6-1, 2, 3, 4-tetrahydronaphthyl) butoxy) pentyl group, a group 6- ( 5- (5-1, 2, 3, 4-tetrahydronaphthyl) pentoxy) hexyl, a 1,1-dimethyl-2- (4- (6-1, 2,3,4-tetrahydronaphthyl) pentoxy) ethyl group, a 2-methyl-3- (6- (6-1,2,3,4-tetrahydronaphthyl) hexyloxy) propyl group, a group (1,1,4,4-tetramethyl-6-1, 2, 3, 4- tetrahydronaphthyl) methoxymethyl, a group (1,1,4-trimethyl-6-1, 2,3,4-tetrahydronaphthyl) methoxymethyl, a group (1,1-dimethyl-6-1, 2,3,4-tetrahydronaphthyl) methoxymethyl, a (1,1-dimethyl-7-1,2,3,4-tetrahydronaphthyl) methoxymethyl group, a (l-methyl-6-1,2,3,4-tetrahydronaphthyl) methoxymethyl group, a group (1 , 4-dimethyl-6-l, 2, 3, 4-tetrahydronaphthyl) methoxymethyl, a group (1, 1, 4, 4-tetraethyl-6-l, 2, 3, 4-tetrahydronaphthyl) methoxymethyl, a group (1 , l-dimethyl-4-ethyl-6-1, 2, 3, 4-tetrahydronaphthyl) methoxymethyl, a group (1,1-di-n-propyl-6-1, 2, 3, 4-tetrahydronaphthyl) methoxymethyl, a group (4,4-di-n-butyl-6-l, 2, 3, 4-t) etrahydronaphthyl) methoxymethyl, a group (ln-pentyl-6-1, 2, 3, 4-tetrahydronaphthyl) methoxymethyl, a group (1,4-di-n-hexyl-β-1, 2, 3, 4-tetrahydronaphthyl) methoxymethyl, and a group (l-methyl-5-n-propyl-4-ethyl-6-l, 2,3,4-tetrahydronaphthyl) methoxymethyl [wherein, in the 1, 2, 3, 4-tetrahydronaphthalene ring, C 1 -C 4 alkyl groups up to 4 can be substituted]. Examples of the C 1 -C 6 alkyl group substituted with C 1 -C 6 alkoxy carbamoyl [wherein, in the amino group, at least one selected from the group consisting of a C3-C8 cycloalkyl group and a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a group substituted or unsubstituted Cl-Cβ alkyl with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] can include Cl-Cß alkyl groups substituted with C 1 -C 6 alkoxy carbamoyl such as a group carbamoylmethoxymethyl, a 2- (carbamoylethoxy) methyl group, a (3-carbamoylpropoxy) methyl group, a (2-carbamoylpropoxy) methyl group, a (4-carbamoylbutoxy) methyl group, a (5-carbamoylpentoxy) methyl group, a group (4-carbamoylpentoxy) methyl, a (6-carbamoylhexyloxy) methyl group, a (2-carbamoylmethoxy) ethyl group, a 1- (2-carbamoylethoxy) ethyl group, a 3- (3-carbamoylpropoxy) propyl group, a group 4 - (2-carbamoylpropoxy) butyl, a 5- (carbamoylmethoxy) pentyl group, a 4- ( 2- carbamoylpropoxy) butyl, a 6- (4-carbamoylbutoxy) hexyl group, a 1, 1-dimethyl-2- (5-carbamoylpentoxy) ethyl group, a 2-methyl-3- (4-carbamoylpentoxy) propyl group, a 2- (6-carbamoylhexyloxy) ethyl group, a group (N- (4-methylphenyl) carbamoyl) methoxymethyl, a group (N- (4-chlorophenyl) carbamoyl) methoxymethyl, a group (N- (4-trifluoromethylphenyl) carbamoyl) methoxymethyl, a group (N- (4-methoxyphenyl) carbamoyl) methoxymethyl, a group (N- (4-trifluoromethoxyphenyl) carbamoyl) methoxymethyl, a group (N- (2,4-dichlorophenyl) -carbamoyl) methoxymethyl, a group ( N- (2,4-, 6-trimethylphenyl) carbamoyl) methoxymethyl, a (N- (2,4-dimethoxyphenyl) carbamoyl) methoxymethyl group, a (N-cyclohexylcarbamoyl) methoxymethyl group, a (N-cyclopentylcarbamoyl) methoxymethyl group, a group (N-cycloheptylcarbamoyl) methoxymethyl, a group (N-cyclooctylcarbamoyl) methoxymethyl, a group (N-cyclobutylcarbamoyl) methoxymethyl, a group (N-cyclopropylcarbamoyl) methoxymethyl, a group (N-cyclopropyl-N-cyclohexylcarbam oil) methoxymethyl, a group (N, N-dicyclohexylcarbamoyl) methoxymethyl, a group (N-cyclopropyl-N- (4-fluoromethylphenyl) carbamoyl) -methoxymethyl, and a group (N-cyclohexyl-N- (4-fluoromethylphenyl) carbamoyl) ) methoxymethyl (wherein, in the amino group, 1 or 2 groups selected from the group consisting of the C3-C8 cycloalkyl group described above and the phenyl group described above [wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted). Examples of the C 1 -C 6 alkyl group substituted with C 1 -C 6 alkoxy benzofuryl [wherein, in the benzofuran ring, at least one cyano group can be substituted] can include C 1 -C 6 alkyl groups substituted with C 1 -C 6 alkoxy benzofuryl such as a (2-benzofuryl) methoxymethyl group, a (2- (3-benzofuryl) ethoxy) methyl group, a (3- (4-benzofuryl) propoxy) methyl group, a (2- (5-benzofuryl) propoxy) methyl group, a group (4- (6-benzofuryl) butoxy) methyl, a group (5- (7-benzofuryl) pentoxy) methyl, a group (4- (2-benzofuryl) pentoxy) methyl, a group (6- (3- benzofuryl) exyloxy) methyl, a (2- (2-benzofuryl) methoxy) ethyl group, a l- (2- (3-benzofuryl) ethoxy) ethyl group, a 3- (3- (4-benzofuryl) propoxy group) propyl, a 4- (2- (5-benzofuryl) propoxy) butyl group, a 5- (4- (6-benzofuryl) butoxy) pentyl group, a 6- (5- (7-benzofuryl) pentoxy) hexyl group, a 1, 1-dimethyl-2- (4- (2-benzofuryl) pentoxy) ethyl group, a 2-methyl-3- (6- (3-benzofuryl) hexyloxy) propyl group, a group (7-cyano- 2-benzofuryl) methoxymethyl, a (6-cyano-2-benzofuryl) methoxymethyl group, a (5-cyano-2-benzofuryl) methoxymethyl group, a (4-cyano-2-benzofuryl) methoxymethyl group, a group (3- cyano-2-benzofuryl) methoxymethyl, a (2-cyano-5-benzofuryl) methoxymethyl group, a group (6,7-dicyano-2-benzofuryl) methoxymethyl, and a group (3, 4, 5-triciano-2-benzofuryl) methoxymethyl [wherein, in the benzofuran ring, 1 to 3 cyano groups can be substituted]. Examples of the C7-C10 alkoxy group may include an n-heptyloxy group, an n-octyloxy group, an n-nonyloxy group, an n-decyloxy group, a 5-methylhexyloxy group, a 4,4-di ethylpentyloxy group, an 6-methylheptyloxy group, and a 5,5, 5-trimethylpentyloxy group. Examples of the phenoxy group [wherein, in the phenyl ring, at least one selected from the group consisting of a Cl-Cβ phenyl alkoxy group, a C3-C8 cycloalkyl group, a C7-C10 alkoxy group, and a phenoxy group is substituted] may include phenoxy groups such as a 4-benzyloxyphenoxy group, a 4-cyclohexylphenoxy group, a 4-n-octiloxifenoxi, 4-cyclopentylphenoxy group, a 3-phenoxyphenoxy group, a 3-benzyloxyphenoxy group, a 3- cyclohexylphenoxy group, a 3-n-octiloxifenoxi, a 3-cyclopentylphenoxy group, a 4-phenoxyphenoxy group, a 2- benzyloxyphenoxy group, a 2-cyclohexylphenoxy group, a 2-n- heptiloxifenoxi, a 2-cyclopentylphenoxy group, a 2- phenoxyphenoxy, a 4- (2-phenylethoxy) phenoxy group, a 4-cyclooctylphenoxy group, a 4-n-nonyloxyphenoxy group, a 4-cyclopropylphenoxy group, a 2,3-diphenoxyphenoxy group, a 4- (3-) group phenylpropoxy) phenoxy, a 4-cycloheptylphenoxy group, a 4-n-decyloxyphenoxy group, a 4-cyclobutylphenoxy group, a 2, 4, 6-t group rifenoxifenoxi, 4- (4-phenylbutoxy) phenoxy group, a 2, 4-diciclohexilfenoxi, 2,4-di-n-octiloxifenoxi group, a 2, 4, 6-triciclopentilfenoxi, a 3-phenoxy-4 -benciloxifenoxi, 4- (5-phenylpentyloxy) phenoxy group, un-cyclohexyl-3-phenoxyphenoxy group 4, 6-tri-n-octiloxifenoxi group, a 4-cyclopentyl-2-benzyloxyphenoxy group, 2, 4, a group 3-phenoxy-2-cyclohexylphenoxy, 4- (6-phenylhexyloxy) phenoxy group, a group 3,4,5-tribenciloxifenoxi, and a 2, 4-dibenciloxifenoxi, provided that, on the phenyl ring, 1 to 3 groups selected from the group consisting of the C1-C6 alkoxy phenyl group described above, the C3-C8 cycloalkyl group described above, the C7-C10 alkoxy group described above, and the phenoxy group described above, are substituted. Examples of the 2, 3-dihydrobenzofuryloxy group [wherein, in the 2, 3-dihydrobenzofuran ring, at least one oxo group can be substituted] can include 2,3-dihydrobenzofuryloxy groups such as a group (2-, 3-, 4-, 5-, 6- or 7-) 2, 3-dihydrobenzofuryloxy, a 3-oxo-6-2,3-dihydrobenzofuryloxy group, and a 2-oxo-5-2,3-dihydrobenzofuryloxy group, provided that, in the 2,3-dihydrobenzofuran ring, 1 or 2 oxo groups can be substituted. Examples of the benzothiazolyloxy group [wherein, in the benzothiazole ring, at least one Cl-Cß alkyl group can be substituted] can include benzothiazolyloxy groups such as a group (2-, 4-, 5-, 6- or 7-) benzothiazolyloxy a 2-benzothiazolyloxy-methyl-5-benzothiazolyloxy 2-ethyl-5-benzothiazolyloxy 2-n-propyl-5-tert butyl-5-benzothiazolyloxy 2-group, a group, a group, a group, a 2- n-pentyl-5-benzothiazolyloxy, a 2-n-hexyl-5-benzothiazolyloxy group, a 2,5-dimethyl-β-benzothiazolyloxy group, and a 4,5,6-trimethyl-2-benzothiazolyloxy group, provided that, in the benzothiazole ring, the C1-C6 alkoyl groups 1 to 3 described above can be substituted. Examples of the C 1 -C 6 alkoxy furyl group [wherein, in the furan ring, at least one C 1 -C 6 alkoxycarbonyl group can be substituted] can include C 1 -C 6 alkoxy furyl groups such as a (2- or 3-) furylmethoxy group , a 2- ((2- or 3-) furyl) ethoxy group, a l - ((2- or 3-) furyl) ethoxy group, a 3- ((2- or 3-) furyl) propoxy group, a 2- ((2- or 3-) furyl) propoxy group, a 4- ((2- or 3-) furyl) butoxy group, a 5- ((2- or 3-) furyl) pentoxy group, a group 4 - ((2- or 3-) furyl) pentoxy, a 6- ((2- or 3-) furyl) hexyloxy group, a 2-methyl-3- ((2- or 3-) furyl) propoxy group, a group 1, l-dimethyl-2- ((2- or 3-) furyl) ethoxy, a 2-ethoxycarbonyl-5-furylmethoxy group, a 2-ethoxycarbonyl-5-furylmethoxy group, a 2-methoxycarbonyl-4-furylmethoxy group, a 2-propoxycarbonyl-3-furylmethoxy group, a 2-butoxycarbonyl-5-furylmethoxy group, a 2-pentyloxycarbonyl-5-furylmethoxy group, a 2-hexyloxycarbonyl-5-furylmethoxy group , a 2, 3-diethoxycarbonyl-5-furylmethoxy group, and a 2,3,4-trimethoxycarbonyl-5-furylmethoxy group, provided that, in the furan ring, the alkoxycarbonyl Cl-Cß 1 to 3 groups described above may be used. be replaced. Examples of the C1-Cβ-tetrazolyl alkoxy group [wherein, in the tetrazole ring, at least one selected from the group consisting of a Cl-Cß phenyl alkyl group and a Cl-Cβ cycloalkyl C 3 -C 8 alkyl group can be substituted] can include Cl-Cβ tetrazolyl alkoxy groups such as a (1-, 2- or 5-) tetrazolylmethoxy group, a 2 - ((1--, 2- or 5-) tetrazolyl) ethoxy group, a group 1 - ((1- , 2- or 5-) tetrazolyl) ethoxy, a 3 - ((1-, 2- or 5-) tetrazolyl) propoxy group, a 2 - ((1-, 2- or 5-) tetrazolyl) propoxy group, a group 4 - ((1-, 2- or 5-) tetrazolyl) butoxy, a group 5 - ((1-, 2- or 5-) tetrazolyl) pentoxy, a group 4 - ((1-, 2- or 5) -) tetrazolyl) pentoxy, a 6 - ((l-, 2- or 5-) tetrazolyl) hexyloxy group, a 2-methyl-3- ((1-, 2- or 5-) tetrazolyl) propoxy group, a group 1, l-dimethyl-2- ((1-, 2- or 5-) tetrazolyl) ethoxy, a 1- (2-phenylethyl) -5-tetrazolylmethoxy group, a 1-cyclohexylmethyl-5-tetrazolylmethoxy group, a group of -benzyl-l-tetrazolylmethoxy, a 5- (2-cyclopentylethyl) group - 1-tetrazolylmethoxy, a 1-benzyl-5-tetrazolylmethoxy group, a 1- (3-phenylpropyl) -5-tet azolylmethoxy group, a 1- (4-phenylbutyl) -5-tet azolylmethoxy group, a 1- (5-methyl) group phenylpentyl) -5-tetrazolylmethoxy, a 1- (6-phenylhexyl) -5-tetrazolylmethoxy group, a 1-cyclobutylmethyl-5-tetrazolylmethoxy group, a 1- (3-cyclopropylpropyl) -5-tetrazolylmethoxy group, a group 1- (4-cycloheptylbutyl) -5-tetrazolylmethoxy, a 1- (5-cyclooctylpentyl) -5-tetrazolylmethoxy group, and a 1- (6-cyclohexylhexyl) -5-tetrazolylmethoxy group, provided that, in the tetrazole ring, a group selected from the group consisting of the alkyl group C1-C6 phenyl described above and the C3-C8 cycloalkyl C1-C6 alkyl group described above may be substituted. Examples of the C 1 -C 6 alkoxy 1,2,4-oxadiazolyl group [wherein, in the 1, 2, 4-oxadizol ring, a phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted)) can include C1-C6 alkoxy groups 1,2,4-oxadiazolyl such as a group (3- or 5-) 1,2,4-oxadiazolylmethoxy, a 2- ((3- or 5-) 1,2,4-oxadiazolyl) ethoxy group, a l - ((3- or 5-) 1,2,4-oxadiazolyl group) ethoxy, a 3 - ((3- or 5-) I, 2,4-oxadiazolyl) propoxy group, a 2 - ((3- or 5-) I, 2,4-oxadiazolyl) propoxy group, a 4- group ((3- or 5-) l, 2,4-oxadiazolyl) butoxy, a 5 - ((3- or 5-) l, 2,4-oxadiazolyl) pentoxy group, a group 4 - ((3- or 5) -) l, 2,4-oxadiazolyl) pentoxy, a group 6 - ((3- or 5-) l, 2,4-oxadiazolyl) hexyloxy, a group 2-methyl-3- ((3- or 5-) 1,2,4-oxadiazolyl) propoxy, a 1, l-dimethyl-2- ((3- or 5-) 1,2,4-oxadiazolyl) ethoxy group, a 3- (4-tert-butylphenyl) -5-1,2,4-oxadiazolylmethoxy group, a 3-phenyl-5-1,2,4-oxadiazolylmethoxy group, a 3- (4-chlorophenyl) -5-1 group , 2,4-oxadiazolylmethoxy, a group 3- (4-trifluoromethylphenyl) -5-1,2,4-oxadiazolylmethoxy, a 5- (4-trifluoromethoxyphenyl) -3-1,2,4-oxadiazolylmethoxy group, a 5- (4-methoxyphenyl) -3- group 1, 2, 4-oxadiazolylmethoxy, a group - (2,4-Dimethylphenyl) -3-1,2,4-oxadiazolylmethoxy, a 3- (2,4-, 6-trimethylphenyl) -5-1,2,4-oxadiazolylmethoxy group, a 3- (2) group , 4-dimethylphenyl) -5-1, 2,4-oxadiazolylmethoxy, a 5- (2,4,6-trimethoxyphenyl) -3-1,2,4-oxadiazolylmethoxy group, a 3- (2,4-dibromophenyl) group ) -5-1, 2, 4-oxadiazolylmethoxy, a 3- (2,4,6-trifluorophenyl) -5-1,2,4-oxadiazolylmethoxy group, a 3- (3,5-dichlorophenyl) -5- group 1,2,4-oxadiazolylmethoxy, a 3- (2-methyl-5-chlorophenyl) -5-1,2,4-oxadiazolylmethoxy group, a 3- (3-methoxy-5-chlorophenyl) -5-1 group, 2,4-oxadiazolylmethoxy and a 3- (2,3,4,5,6-pentafluorophenyl) -5-1,2, 4-oxadiazolylmethoxy group, provided that, in the 1,2,4-oxadiazole ring , the phenyl group described above can be substituted (wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen, and a substituted C1-Cβ alkoxy group or not substituted with halogen can be substituted). Examples of the C 1 -C 6 alkoxy benzothienyl group [wherein, in the benzothiophene ring, at least one halogen atom can be substituted] can include C 1 -C 6 alkoxy benzothienyl groups such as a group (2-, 3-, 4-, 5-, 6- or 7-) benzothienylmethoxy, a 2- ((2-, 3-, 4-, 5-, 6- or 7-) benzothienyl) ethoxy group, a group l - ((2-, 3- , 4-, 5-, 6- or 7-) benzothienyl) ethoxy, a 3- ((2-, 3-, 4-, 5-, 6- or 7-) benzothienyl) propoxy group, a 2- ( (2-, 3-, 4-, 5-, 6- or 7-) benzothienyl) propoxy, a group 4- ((2-, 3-, 4-, 5-, 6- or 7-) benzothienyl) - butoxy, a group 5- ((2-, 3-, 4-, 5-, 6- or 7-) benzothienyl) pentoxy, a group 4- ((2-, 3-, 4-, 5-, 6- or 7-) benzothienyl) pentoxy, a 6- ((2-, 3-, 4-, 5-, 6- or 7-) benzothienyl) hexyloxy group, a 2-methyl-3- ((2-, 3) group -, 4-, 5-, 6- or 7-) benzothienyl) propoxy, a 1, l-dimethyl-2- ((2-, 3-, 4-, 5-, 6- or 7-) benzothienyl group) ethoxy, a 5-chloro-3-benzothienylmethoxy group, a 4-bromo-2-benzothienylmethoxy group, a β-fluoro-5-benzothienyl group ethoxy, a 7-iodo-4-l, 2,4-oxadiazolylmethoxy group, a 4,5-dichloro-3-benzothienylmethoxy group, and a 3,4,5-trifluoro-2-benzothienylmethoxy group, provided that, in the benzothiophene ring, 1 to 3 halogen atoms can be substituted. Examples of the Cl-Cβ isoxazolyl alkoxy group [wherein, in the isoxazole ring, at least one Cl-Cß alkyl group can be substituted] can include Cl-Cβ isoxazolyl alkoxy groups such as a group (3-, 4- or 5-) isoxazolylmethoxy, a 2- ((3-, 4- or 5-) isoxazolyl) ethoxy group, a group l - ((3-, 4- or 5-) isoxazolyl) ethoxy, a group 3 - ((3-, 4- or 5-) isoxazolyl) propoxy, a 2- ((3-, 4- or 5-) isoxazolyl) propoxy group, a group 4- ((3-, 4- or 5-) isoxazolyl) butoxy, a 5- ((3-, 4- or 5-) isoxazolyl) pentoxy group, a 4- ((3-, 4- or 5-) isoxazolyl) pentoxy group, a group 6- ((3- , 4- or 5-) isoxazolyl) hexyloxy, a group 2-meettiill-33-- (((((33---, r 4- or 5-) isoxazolyl) propoxy, a group 1, l-dimethyl-2 - ((3-, 4- or 5-) isoxazolyl) ethoxy, a group (3,5-dimethyl-4-isoxazolyl) methoxy, a group (3-methyl-5-isoxazolyl) methoxy, a group (4-ethyl) -5-isoxazolyl) methoxy, a group (5-n-propyl-4-isoxazolyl) methoxy, a group (3-tert-butyl-4-isoxazolyl) methoxy, a group (4-n-pentyl-5-isoxazolyl) methoxy, and a group (5-n-hexyl-5-isoxazolyl) methoxy, provided that, in the isoxazole ring, the Cl-Cß 1 or 2 alkyl groups can be substituted.

Examples of the C 1 -C 3, 4, 4-oxadiazolyl alkoxy group [wherein, in the 1,3,4-oxadiazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one alkyl group Cl-Cβ may be substituted)) may include Cl-Cβ 1, 3, 4-oxadiazolyl alkoxy groups such as a 2-1,3,4-oxadiazolylmethoxy group, a 2- (2-1, 3,4 group oxadiazolyl) ethoxy, a 1- (2-1, 3, 4-oxadiazolyl) ethoxy group, a 3- (2-1, 3, 4-oxadiazolyl) propoxy group, a 2- (2-1, 3, 4- oxadiazolyl) propoxy, a 4- (2-1, 3, 4-oxadiazolyl) butoxy group, a 5- (2-1, 3, -oxadiazolyl) pentoxy group, a 4- (2-1, 3, 4- oxadiazolyl) pentoxy, a 6- (2-1, 3, 4-oxadiazolyl) hexyloxy group, a 2-methyl-3- (2-1, 3, 4-isoxazolyl) propoxy group, a group 1,1- dimethyl-2- (2-1, 3, 4-oxadiazolyl) ethoxy, a 2- (4-methylphenyl) -5-1, 3, 4-oxadiazolylmethoxy group, a 3-phenyl-5-1, 3, 4 group -oxadiazolylmethoxy, a 2- (4-ethylphenyl) -5-1, 3, -oxadiazolylmethoxy group, a 3- (4-n-propylphenyl) -5 group -1, 3, 4-oxadiazolylmethoxy, a 3- (4-sec-butylphenyl) -5-1, 3, 4-oxadiazolylmethoxy group, a 3- (4-n-pentylphenyl) -5-1, 3, 4 group - • oxadiazolylmethoxy, a 3- (2,4-dimethylphenyl) -5-1, 3, 4-oxadiazolylmethoxy group, a 3- (2,4-, 6-trimethylphenyl) -5-1, 3, 4-oxadiazolylmethoxy group, a 3- (3-n-hexylphenyl) -5-1, 3, 4-oxadiazolylmethoxy group, a 3- (2-methylphenyl) -5-1, 3, 4-oxadiazolylmethoxy group, and a 3- (3-) group methylphenyl) -5-1, 3, 4-oxadiazolylmethoxy, provided that, in the 1,3,4-oxadiazole ring, a phenyl group can be substituted (wherein, in the phenyl ring, the C1-C6 alkyl groups 1 to 3 described above can be replaced). Examples of the C1-C6 alkoxy naphthyl groups may include a (2- or 3-) naphthylmethoxy group, a 2- ((2- or 3-) aftyl) ethoxy group, a l- ((2- or 3-) group. ) naphthyl) ethoxy, a 3- ((2- or 3-) naphthyl) -propoxy group, a 2- ((2- or 3-) naphthyl) propoxy group, a 4- ((2- or 3-) group) naphthyl) butoxy, a 5- ((2- or 3-) naphthyl) pentoxy group, a 4- ((1- or 2-) naphthyl) pentoxy group, a 6- ((2- or 3-naphthyl) group) hexyloxy, a 2-methyl-3- ((2- or 3-) naphthyl) propoxy group, and a 1,1-dimethyl-2- ((2- or 3-) naphthyl) ethoxy group. Examples of the C1-C6 alkoxy pyridyl group (wherein, in the pyridine ring, at least one C1-C6 alkyl group substituted or unsubstituted with halogen can be substituted) can include C1-C3 pyridyl alkoxy groups such as a group (1 -, 2-, 3- or 4-) pyridylmethoxy, a 2 - ((l-, 2-, 3- or 4-) iridyl) ethoxy group, a group 1 - ((1-, 2-, 3- or 4-) pyridyl) ethoxy, a 3 - ((l-, 2-, 3- or 4-) pyridyl) ropoxy group, a 2 - ((l-, 2-, 3- or 4-) pyridyl) propoxy group , a 4 - ((l-, 2-, 3- or 4-) pyridyl) butoxy group, a 5 - ((1-, 2-, 3- or 4-) pyridyl) pentoxy group, a group 4- ( (1-, 2-, 3- or 4-) pyridyl) pentoxy, a 6 - ((1-, 2-, 3- or 4-) pyridyl) hexyloxy group, a 2-methyl-3- ((1 -, 2-, 3- or 4-) pyridyl) propoxy, a 1, l-dimethyl-2- ((1-, 2-, 3- or 4-) pyridyl) ethoxy group, a 2-trifluoromethyl-5 group -pyridylmethoxy, a 2-methyl-5-pyridylmethoxy group, a 2-ethyl-6-pyridylmethoxy group, a 3-n-propyl-2-pyridylmethoxy group, a 4-n-butyl-5-pyridylmethoxy group, a 3-group -n-pentyl-4-pyridylmethoxy, a 2-n-hexyl-6-pyridylmethoxy group, a 2,3-ditrifluoromethyl-5-pyridylmethoxy group, a 3,4,5-tritrifluoromethyl-2-pyridylmethoxy group, a 2, 4-dimethyl-5-pyridylmethoxy group, and a 3, 4, 5-trimethyl-2-pyridylmethoxy group, provided that, in the pyridine ring, 1 to 3 Cl-Cß alkyl groups substituted or not substituted by halogen can be substituted. Examples of the Cl-Cβ thiazolyl alkoxy group [wherein, in the thiazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted)) can include Cl-Cβ thiazolyl alkoxy groups such as a group (2-, 4- or 5) -) thiazolylmethoxy, a group 2- ((2-, 4- or 5-) thiazolyl) ethoxy, a group l - ((2-, 4- or 5-) thiazolyl) ethoxy, a group 3- ((2-, 4- or 5-) thiazolyl) propoxy, a 2- ((2-, 4- or 5-) thiazolyl) propoxy group, a 4- ((2-, 4- or 5-) thiazolyl) butoxy group, a 5- group ((2-, 4- or 5-) thiazolyl) pentoxy, a 4- ((2-, 4- or 5-) thiazolyl) pentoxy group, a β - ((2-, 4- or 5-) thiazolyl group ) hexyloxy, a 2-methyl-3- ((2-, 4- or 5-) thiazolyl) ropoxy group, a 1, l-dimethyl-2- ((2-, 4- or 5-) thiazolyl) ethoxy group , a 2- (4-trifluoromethylphenyl) -4- thiazolylmethoxy group, a 2-phenyl-4-thiazolylmethoxy group, a 2- (4-chlorophenyl) -4-thiazolylmethoxy group, a 2- (4-trifluoromethylphenyl) -5 group -thiazolylmethoxy, a 2- (4-trifluoromethoxyphenyl) -4-thiazolylmethoxy group, a 5- (4-methoxyphenyl) -3-thiazolylmethoxy group, a b- (2,4-dimethylphenyl) -2-thiazolylmethoxy group, a group 4 - (2,4,6-trimethylphenyl) -2-thiazolylmethoxy, a 2- (2,4-dimethylphenyl) -5-thiazolylmethoxy group, a 2- (2,4,6-trimethoxyphenyl) -4-thiazolylmethoxy group, a group 2- (2 , 4-dibromophenyl) -4-thiazolylmethoxy, a 2- (2,4,6-trifluorophenyl) -5-thiazolylmethoxy group, a 2- (3,5-dichlorophenyl) -4-thiazolylmethoxy group, a 2- (2-group -methyl-5-chlorophenyl) -4-thiazolylmethoxy, a 2- (3-methoxy-5-chlorophenyl) -4-thiazolylmethoxy group, a 2- (2, 3, 4, 5, 6-pentafluorophenyl) -4- group thiazolylmethoxy, and a 2,5-diphenyl-4-thiazolylmethoxy group, provided that, in the thiazole ring, the phenyl groups 1 or 2 described above can be substituted (wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted).

Examples of the Cl-Cβ 1,2,3,4-tetrahydronaphthyl alkoxy group (wherein, in the 1,2,3,4-tetrahydronaphthalene ring, at least one Cl-Cß alkyl group can be substituted) can include alkoxy groups Cl-Cβ 1,2,3,4-tetrahydronaphthyl such as a group (1-, 2-, 5- or 6-) 1, 2, 3, 4-tetrahydronaphthylmethoxy, a group 2 - ((1-, 2- , 5- or β-) 1, 2, 3, 4-tetrahydronaphthyl) ethoxy, a group 1 - ((1-, 2-, 5- or 6-) 1,2,3,4-tetrahydronaphthyl) ethoxy, a group 3 - ((1-, 2-, 5- or 6-) 1, 2, 3, 4-tetrahydronaphthyl) propoxy, a group 2 - ((1-, 2-, 5- or 6-) 1, 2 , 3, 4-tetrahydronaphthyl) propoxy, a 4 - ((l- or 2-) 1, 2, 3, 4-tetrahydronaphthyl) butoxy group, a 5 - ((1-- or 2-) 1, 2, 3 group , 4-tetrahydronaphthyl) pentoxy, a 4 - ((1-, 2-, 5- or β-) 1, 2, 3, 4-tetrahydronaphthyl) pentoxy group, a group 6 - ((1-, 2-, 5 -6-6) 1, 2, 3, 4-tetrahydronaphthyl) hexyloxy, a 2-methyl-3- ((1-, 2-, 5- or 6-) 1, 2, 3, 4-tetrahydronaphthyl) propoxy group , a 1, l-dimethyl-2- ((1-, 2-, 5- or 6-) 1,2, 3,4-tetrahydronaphthyl) ethoxy group, a group (1, 1, 4, 4-tetramethyl-6-1, 2, 3, 4-tetrahydronaphthyl) methoxy, a group (1, 1, 4-trimethyl-β-1,2,3,4-tetrahydronaphthyl) methoxy, a group (1,1-dimethyl-β-1,2,3,4-tetrahydronaphthyl) methoxy, a group (4,4-dimethyl-6-1,2,3,4-tetrahydronaphthyl) methoxy, a group (1-methyl-β-1,2,4,4-tetrahydronaphthyl) methoxy, a group (1,4-dimethyl-β-1, 2, 3, 4-tetrahydronaphthyl) methoxy, one group (1, 1, 4) , 4-tetraethyl-6-1, 2, 3, 4-tetrahydronaphthyl) methoxy, a group (1, 1-dimethyl-4-ethyl-β-1, 2, 3, 4-tetrahydronaphthyl) methoxy, a group (1 , 1-di-n-propyl-6-1, 2, 3, 4-tetrahydronaphthyl) methoxy, a group (4,4-di-n-butyl-6-1, 2, 3, 4-tetrahydronaphthyl) methoxy, a group (1-n-pentyl-6-1, 2, 3, 4-tetrahydronaphthyl) methoxy, a group (1,4-di-n-hexyl-6-1, 2, 3, 4-tetrahydronaphthyl) methoxy, and a group (1-methyl-5-n-propyl-4-ethyl-6-l, 2,3,4-tetrahydronaphthyl) methoxy, provided that, in the 1, 2, 3, 4-tetrahydronaphthalene ring, the C 1 -C 4 alkyl groups up to 4 described above can be substituted. Examples of the Cl-Cβ phenoxy alkoxy group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen, and an alkoxy Cl group) -Cβ substituted or unsubstituted with halogen can be substituted) can include Cl-Cβ phenoxy alkoxy groups such as a phenoxymethoxy group, a 2-phenoxyethoxy group, a 1-phenoxyethoxy group, a 3-phenoxypropoxy group, a 2-phenoxypropoxy group, a 4-phenoxybutoxy group, a 5-phenoxypentoxy group, a 4-phenoxypentoxy group, a 6-phenoxyhexyloxy group, a 2-methyl-3-phenoxypropoxy group, a 1, 1-dimethyl-2-phenoxyethoxy group, a 2-group fluorophenoxymethoxy, a 3-fluorophenoxymethoxy group, a 4-fluorophenoxymethoxy group, a 2- (2-fluorophenoxy) ethoxy group, a 2- (3-fluorophenoxy) ethoxy group, a 2- (4-fluorophenoxy) ethoxy group, a 2-group -chlorophenoxymethoxy, a 3-chlorophenoxymethoxy group, a 4-chlorophenoxymethoxy group, a 2-fluoro-4-bromophenoxymethoxy group, a group 4-chloro-3-fluorophenoxymethoxy, a 2-chloro-4-fluorophenoxymethoxy group, a 3,4-dichlorophenoxymethoxy group, a 3,5-dichlorophenoxymethoxy group, a 2,3-dichlorophenoxymethoxy group, a 2,5-dichlorophenoxymethoxy group , a 2, 3, 4-trichlorophenoxymethoxy group, a 3, 4, 5-trifluorophenoxymethoxy group, a 2,3,4,5,6-pentafluorophenoxymethoxy group, a 2, 4,6-trichlorophenoxymethoxy group, a 4-isopropylphenoxymethoxy group , a 4-n-butylphenoxymethoxy group, a 4-methylphenoxymethoxy group, a 2-methylphenoxymethoxy group, a 3-methylphenoxymethoxy group, a 2,4-dimethylphenoxymethoxy group, a 2,3-dimethylphenoxymethoxy group, a 2,6-dimethylphenoxymethoxy group , a 3,5-dimethylphenoxymethoxy group, a 2,5-dimethylphenoxymethoxy group, a 2,4,6-trimethylphenoxymethoxy group, a 4-ethylphenoxymethoxy group, a 4-isopropylphenoxymethoxy group, a 3,5-ditrifluoromethylphenoxymethoxy group, a 4-group -isopropoxyphenoxymethoxy, a 4-n-butoxyphenoxymethoxy group, a 4-methoxyphenoxymethoxy group, a 2-methoxyphenoxymethoxy group, a 3-methoxy group Noximetoxy, a 2, 4-dimethoxyphenoxymethoxy group, a 2, 3-dimethoxyphenoxymethoxy group, a 2,6-dimethoxyphenoxymethoxy group, a 3,5-dimethoxyphenoxymethoxy group, a 2,5-dimethoxyphenoxymethoxy group, a 2,4,6-trimethoxyphenoxymethoxy group, a 3,5-ditrifluoromethoxyphenoxymethoxy group , a 2-isopropoxyphenoxymethoxy group, a 3-chloro-4-methoxyphenoxymethoxy group, a 2-chloro-4-trifluoromethoxyphenoxymethoxy group, a 3-methyl-4-fluorophenoxymethoxy group, a 4-bromo-3-trifluoromethylphenoxymethoxy group, a group 2 - (2-chlorophenoxy) ethoxy, a 2- (3-chlorophenoxy) ethoxy group, a 2- (4-chlorophenoxy) ethoxy group, a 2-trifluoromethylphenoxymethoxy group, a 3-trifluoromethylphenoxymethoxy group, a 4-trifluoromethylphenoxymethoxy group, a group 2-trifluoromethoxyphenoxymethoxy, a 3-trifluoromethoxyphenoxymethoxy group, a 4-trifluoromethoxyphenoxymethoxy group, a 2- (2-trifluoromethylphenoxy) ethoxy group, a 2- (3-trifluoromethylphenoxy) ethoxy group, a 2- (4-trifluoromethylphenoxy) ethoxy group, a 2- (2-trifluoromethoxyphenoxy) ethoxy group, a 2- (3-trifluoromethoxyphenoxy) ethoxy group, a 2- [4-trifluoromethoxyphenoxy) ethoxy group, a 3- [2-trifluoromethylphenoxy) propoxy group, a 3-3-trifluoromethylphenoxy) propoxy group, a 3-4-trifluoromethylphenoxy) propoxy group, a 3-3-trifluoromethylphenoxy group) propoxy, a 3-3-trifluoromethoxyphenoxy) propoxy group, a 3- (4-trifluoromethoxyphenoxy) propoxy group, a 4- (3-trifluoromethylphenoxy) butoxy group, a 5- (4-trifluoromethylphenoxy) pentoxy group, a 4- ( 4-trifluoromethylphenoxy) pentoxy, a 4- (4- trifluoromethoxyphenoxy) pentoxy group, a 6- (3-trif luoromethyl-enoxy) hexyloxy group, a 6- (4-trifluoromethyl-enoxy) -hexyloxy group, and a 6-group (4-trifluoromethoxy-enoxy) -hexyloxy, provided that, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of the halogen atom described above, the C1-Cβ alkyl group substituted or not substituted with halogen described above, and the C1-Cβ alkoxy group substituted or unsubstituted with halogen described above can be replaced. Examples of the Cl-Cβ carbamoyl alkoxy group [wherein, in the amino group, at least one selected from the group consisting of a C3-C8 cycloalkyl group and a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] can include C1 alkoxy groups -C6 carbamoyl such as a carbamoylmethoxy group, a 2-carbamoylethoxy group, a 3-carbamoylpropoxy group, a 2-carbamoylpropoxy group, a 4-carbamoylbutoxy group, a 5-carbamoylpentoxy group, a 4-carbamoylpentoxy group, a 6-group carbamoilhexiloxi a-methyl-3-carbamoylpropoxy 2 group, a 1, 1-dimethyl-2-carbamoylethoxy group, a (N- (4-methylphenyl) carbamoyl) methoxy group, (N- (4-clorof enyl) carbamoyl ) methoxy, a group (N- (4-trifluoromethylphenyl) carbamoyl) methoxy, a group po (N- (4-methoxyphenyl) carbamoyl) methoxy, a group (N- (4- trifluoromethoxyphenyl) carbamoyl) methoxy, a group (N- (2,4-dichlorophenyl) carbamoyl) methoxy, a group (N - (2, 4, 6- trimethylphenyl) carbamoyl) methoxy group, a (N- (2, 4-dimethoxyphenyl) carbamoyl) methoxy group, a (N-cyclohexylcarbamoyl) methoxy group, a (N-cyclopentylcarbamoyl) methoxy group, a (N-cicloheptilcarbamoil) methoxy group, a (N-ciclooctilcarbamoil) methoxy group, a (N-cyclobutylcarbamoyl) methoxy group, a (N-cyclopropylcarbamoyl) methoxy group, a (N-cyclopropyl-N-cyclohexylcarbamoyl) ethoxy group, a ( N, N-dicyclohexylcarbamoyl) ethoxy, a group (N-cyclopropyl-N- (4-f luoromethylphenyl) carbamoyl) ethoxy, and a group (N-cyclohexyl-N- (4-f luoromethylphenyl) carbamoyl) methoxy, with such that, in the amino group, 1 or 2 groups selected from the group consisting of the C3-C8 cycloalkyl group described above and the phenyl group described above (wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be replaced. Examples of the C 1 -C 6 alkoxy benzofuryl group (wherein, in the benzofuran ring, at least one cyano group can be substituted) can include Cl-Cβ benzofuryl alkyl group such as a (2-benzofuryl) methoxy group, a group 2 - (3-benzofuryl) ethoxy, a 3- (4-benzofuryl) propoxy group, a 2- (5-benzofuryl) propoxy group, a 4- (6-benzofuryl) butoxy group, a 5- (7-benzofuryl) group pentoxy, a 4- (2-benzofuryl) pentoxy group, a 6- (3-benzofuryl) hexyloxy group, a 2- (2-benzofuryl) methoxy group, a 1-l-dimethyl-2- (2-benzofuryl) group ethoxy, a 2-methyl-3- (3-benzofuryl) propoxy group, a (7-cyano-2-benzofuryl) methoxy group, a (6-cyano-2-benzofuryl) methoxy group, a (5-cyano- 2-benzofuryl) methoxy, a group (4-cyano-2-benzofuryl) methoxy, a group (3-cyano-2-benzofuryl) methoxy, a group (2-cyano-5-benzofuryl) methoxy, and a group (6 , 7-dicyano-2-benzofuryl) methoxy, a group (3,4,5-tricyano-2-benzofuryl) methoxy, provided that, in the benzofuran ring, 1 to 3 cyano groups can be r replaced. Examples of the Cl-c-naphthyloxy alkyl group (wherein, in the naphthalene ring, at least one Cl-Cβ alkoxy group can be substituted) can include C1-Cß-naphthyloxy alkyl groups such as a (1- or 2-) naphthyloxymethyl group , a 2 - ((l- or 2-) naphthyloxy) ethyl group, a 1 - ((1- or 2-) naphthyloxy) ethyl group, a 3- ((1- or 2-) naphthyloxy) propyl group, a group 2 - ((1- or 2-) naphthyloxy) butyl, a 5 - ((1- or 2-) naphthyloxy) pentyl group, a 4 - ((1-- or 2-) naphthyloxy) pentyl group, a group 6 - ((1- or 2-) naphthyloxy) hexyl, a 2-methyl-3 - ((1- or 2-) naphthyloxy) propyl group, a 1, 1-dimethyl-2- ((1- or 2- ) naphthyloxy) ethyl, a 2- (4-methoxy-1-naphthyloxy) ethyl group, a (4-methoxy-1-naphthyloxy) methyl group, a 2- (3-ethoxy-1-naphthyloxy) ethyl group, a group 2-n-propoxy-1-naphthyloxymethyl, a 5-tert-butoxy-2-naphthyloxymethyl group, a 6-n-pentyloxy-3-naphthyloxymethyl group, a 7-n-hexyloxy-4-naphthyloxymethyl group, a 2- group (2,4-dimethoxy-l-naphthyloxy) ethyl, and a 2- (1, 2, 3, 4-tetramethoxy-5) group -naphthyloxy) ethyl, provided that, in the naphthalene ring, the C 1 -C 4 alkoxy groups described above can be substituted. Examples of the Cl-Cβ benzothiazolyloxy alkyl group (wherein, in the benzothiazole ring, at least one Cl-Cß alkyl group can be substituted) can include Cl-Cβ benzothiazolyloxy alkyl groups such as a group (2-, 4-5 -, 6- or 7-) benzothiazolyloxymethyl, a 2- ((2-, 4-, 5-, 6- or 7-) benzothiazolyloxy) ethyl group, a group l - ((2-, 4-, 5-, 6- or 7-) benzothiazolyloxy) ethyl, a 3- ((2-, 4-, 5-, 6- or 7-) benzothiazolyloxy) propyl group, a 2- ((2-, 4-, 5-, 6- or 1-) benzothiazolyloxy) propyl, a 4- ((2-, 4-, 5-, 6- or 7-) benzothiazolyloxy) -butyl group, a group 5- ((2-, 4-, 5- 6-, 7- or 7-) -enotothiazolyloxy) pentyl, a 4- ((2-, 4-, 5-, 6- or 7-) -enotothiazolyloxy) pentyl group, a group 6- ((2-, 4-, 5- , 6- or 7-) benzothiazolyloxy) hexyl, a 2-methyl-3- ((2-, 4-, 5-, 6- or 7-) benzothiazolyloxy) propyl group, a 1, 1-dimethyl-2- group ((2-, 4-, 5-, 6- or 7-) benzothiazolyloxy) ethyl, a 2- (2-methyl-5-benzothiazolyloxy) ethyl group, a (2-methyl-5-benzothiazolyloxy) methyl group, a 2- (4-ethyl-6-benzothiazolyloxy) ethyl group, a (2-n-propyl-4-benzothiazolyloxy) methyl group, a (5-tert-butyl-6-benzothiazolyloxy) methyl group, a group (6-) n-pentyl-7-benzothiazolyloxy) methyl, a (7-n-hexyl-5-benzothiazolyloxy) ethyl group, a 2- (2,4-dimethyl-5-benzothiazolyloxy) ethyl group, and a 2- (2, 4,5-trimethyl-7-benzothiazolyloxy) ethyl, provided that, in the benzothiazole ring, the C 1 -C 3 alkyl groups described above can be substituted. Examples of the Cl-Cβ quinolyloxy alkyl group (wherein, in the quinoline ring, at least one Cl-Cß alkyl group can be substituted) can include Cl-Cβ quinolyloxy alkyl group such as a group (2-, 3-, 4-, 5-, 6-, 7- or 8-) quinolyloxymethyl, a 2- ((2-, 3-, 4-, 5-, 6-, 7- or 8-) quinolyloxy group) ethyl, a group l - ((2-, 3-, 4-, 5-, 6-, 7- or 8-) quinolyoxy) ethyl, a group 3- ((2-, 3-, 4-, 5- , 6-, 7- or 8-) quinolyloxy) ropyl, a group 2- ((2-, 3-, 4-, 5-, 6-, 7- or 8-) quinolyloxy) propyl, a group 4- ( (2-, 3-, 4-, 5-, 6-, 7- or 8-) quinolyloxy) butyl, a group 5- ((2-, 3-, 4-, 5-, 6-, 7- 8-) quinolyloxy) pentyl, a group 4- ((2-, 3-, 4-, 5-, 6-, 7- or 8-) quinolyloxy) pentyl, a group 6- ((2-, 3-, 4-, 5-, 6-, 7- or 8-) quinolyloxy) hexyl, a 2-methyl-3- ((2-, 3-, 4-, 5-, 6-, 7- or 8-) group) quinolyloxy) propyl, a 1, l-dimethyl-2- ((2-, 3-, 4-, 5-, 6-, 7- or 8-) quinolyloxy) ethyl group, a 2-methyl-8-quinolyloxymethyl group , a group (3-ethyl-7-quinolyloxy) methyl, a group (4-n-propyl-6-quinolyloxy) methyl, a group (5-n-butyl-4-quinolyloxy) methyl, a group (6-n) -hexyl-5-quinolyloxy) methyl, a group (2-methyl-7-quinolyloxy) methyl, a group (7-n-pentyl-6-quinol iloxy) ethyl, a group (8-methyl-2-quinolyloxymethyl), a (2,4-dimethyl-8-quinolyloxy) methyl group, and a (5,6,7-trimethyl-2-quinolyloxy) methyl group, with such that, in the quinoline ring, the C1-C6 alkyl groups up to 3 described above can be substituted. Examples of the C1-C6 alkyl group 2,3-dihydrobenzofuryloxy (wherein, in the 2,3-dihydrobenzofuran ring, at least one selected from the group consisting of a Cl-Cß alkyl group and an oxo group can be substituted) can include Cl-Cß alkyl groups 2, 3-dihydrobenzofuryloxy such as a group (2-, 3-, 4-, -, 6- or 7-) 2, 3-dihydrobenzofuryloxymethyl, a 2- ((2-, 3-, 4-, 5-, 6- or 7-) 2, 3-dihydrobenzofuryloxy) ethyl group, a group - ((2-, 3-, 4-, 5-, 6- or 7-) 2,3-dihydrobenzofuryloxy) ethyl, a group 3- ((2-, 3-, 4-, 5-, 6- 7-) 2, 3-dihydrobenzofuryloxy) propyl, a 2- ((2-, 3-, 4-, 5-, 6- or 7-) 2, 3-dihydrobenzofuryloxy) propyl group, a group 4 - ((2 -, 3-, 4-, 5-, 6- or 7-) 2,3-dihydrobenzofuryloxy) butyl, a group 5- ((2-, 3-, 4-, 5-, 6- or 7-) 2 , 3-dihydrobenzofuryloxy) pentyl, a group 4- ((2-, 3-, 4-, 5-, 6- or 7-) 2, 3-dihydrobenzofuryloxy) pentyl, a group 6 - ((2-, 3- , 4-, 5-, ß- or 7-) 2,3- dihydrobenzofuryloxy) hexyl, a 2-methyl-3- ((2-, 3-, 4-, 5-, 6- or 7-) 2 group , 3-dihydrobenzofuryloxy) propyl, a 1, l-dimethyl-2- ((2-, 3-, 4-, 5-, 6- or 7-) 2,3- dihydrobenzofuryloxy) ethyl group, a 2- ( 2, 2-dimethyl-7-2, 3-dihydrobenzofuryloxy) ethyl, a group (2,2-dimethyl-7-2, 3-dihydrobenzofuryloxy) ethyl, a group 2- (3-ethyl-6-2, 3- dihydrobenzofuryloxy) ethyl, a group (4-n-propyl-5-2, 3-dihydrobenzofuryloxy) methyl, a group (5-tert-butyl-6-2, 3-dihydrobenzofuryloxy) methyl, a group (6-n-pentyl-7-2, 3-dihydrobenzofuryloxy) methyl, a group (7-n-hexyl-5-2, 3-dihydrobenzofuryloxy) methyl, a 2- (2,4-dimethyl-5-2, 3-dihydrobenzofuryloxy) ethyl group, a 2- group (2,2,3-trimethyl-7-2, 3-dihydrobenzofuryloxy) ethyl, a group (2-oxo-5-2, 3-dihydrobenzofuryloxy) methyl, a group (3-oxo-6-2, 3-dihydrobenzofuryloxy) ) methyl, and a group (2-oxo-3-methyl-5-2, 3-dihydrobenzofuryloxy) methyl, provided, in the ring 2, 3-dihydrobenzofuran, 1 to 3 groups selected from the group consisting of the group Cl-Cß alkyl described above and an oxo group can be substituted. Examples of the Cl-Cβ 1,2,3,4-tetrahydronaphthyloxy alkyl group (wherein, in the 1,2,3,4-tetrahydronaphthalene ring, at least one oxo group can be substituted) can include Cl-Cß alkyl group 1,2,3,4-tetrahydronaphthyloxy such as a group (1-, 2-, 5- or 6-) 1, 2, 3, 4-tetrahydronaphthloxymethyl, a group 2 - ((1-, 2-, 5- or 6-) 1, 2, 3, 4-tetrahydronaphthyloxy) ethyl, a group 1 - ((1-, 2-, 5- or β-) 1,2,3,4-tetrahydronaphthyloxy) ethyl, a group 3- ((l-, 2-, 5- or 6-) 1, 2, 3, 4-tetrahydronaphthyloxy) propyl, a group 2 - ((1-, 2-, 5- or 6-) 1, 2, 3, 4-tetrahydronaphthyloxy) propyl, a 4- ((1-, 2-, 5- or 6-) 1, 2, 3, 4-tetrahydronaphthyloxy) butyl group, a 5 - ((1-, 2-, 5- or 6-) 1, 2, 3, 4-tetrahydronaphthyloxy) pentyl, a 4 - ((l- or 2-) 1, 2, 3, 4-tetrahydronaphthyloxy) pentyl group, a group 6 - ((1- or 2) -) 1, 2, 3, 4-tetrahydronaphthyloxy) hexyl a group, a 2-methyl-3- ((1-, 2-, 5- or 6-) 1,2,3,4-tetrahydronaphthyloxy) propyl group, a group 1, l-dimethyl-2- ((1-, 2-, 5- or 6-) 1, 2 , 3,4-tetrahydronaphthyloxy) ethyl, a group (l-oxo- (2-, 5- or 6-) 1, 2, 3, 4-tetrahydronaphthyloxy) methyl, a group (1,4-dioxo- (2- , 5- or 6-) 1, 2, 3, 4-tetrahydronaphthyloxy) methyl, and a 1,2,4-trioxo- (3-, 5-, β-, 7- or 8-) 1, 2 group, 3,4-tetrahydronaphthyloxy) methyl, provided that, in ring 1, 2, 3, 4-tetrahydronaphthalene, 1 to 3 oxo groups can be substituted. Examples of the Cl-Cß 2, 3-dihydro-lH-indenyloxy alkyl group (wherein, in the 2, 3-dihydro-lH-indene ring, at least one oxo group can be substituted) can include Cl-Cß alkyl groups 2, 3-dihydro-lH-indenyloxy such as a group (1-, 2-, 4- or 5-) 2, 3-dihydro-lH-indenyloxymethyl, a group 2 - ((1-, 2-, 4- or 5-) 2, 3-dihydro-lH-indenyloxy) ethyl, a group 1 - ((1-, 2-, 4- or 5-) 2, 3-dihydro-lH-indenyloxy) ethyl, a group 3- ((l-, 2-, 4- or 5-) 2, 3-dihydro-lH-indenyloxy) propyl, a group 2 - ((1-, 2-, 4- or 5-) 2, 3-dihydro- lH-indenyloxy) propyl, a 4 - ((l-, 2-, 4- or 5-) 2, 3-dihydro-iH-indenyloxy) butyl group, a 5 - ((1-, 2-, 4- or 5-) 2, 3-dihydro-lH-indenyloxy) pentyl, a group 4 - ((1-, 2-, 4- or 5-) 2, 3-dihydro-lH-indenyloxy) pentyl, a group 6- ((l-, 2-, 4- or 5-) 2, 3-dihydro-lH-indenyloxy) hexyl, a 2-methyl-3- ((1-, 2-, 4- or 5-) 2 group, 3-dihydro-lH-indenyloxy) propyl, a 1,1-dimethyl-2- ((1-, 2-, 4- or 5-) 2, 3-dihydro-lH-indenyloxy) ethyl group, a group (l-oxo- (2-, 3-, 4-, 5-, 6- or 7 ~) 2, 3-dihydro-lH-indenyloxy) methyl, and a group (1,3-dioxo- (2-, 4- or 5-) 2, 3-dihydro-lH-indenyloxy) methyl, provided that, in the 2, 3-dihydro-lH-indene ring, 1 or 2 oxo groups can be substituted. Examples of the Cl-Cß benzoxathiolanyloxy alkyl group (wherein, in the benzoxathiolane ring, at least one oxo group can be substituted) it can include Cl-Cβ benzoxathiolanyloxy alkyl groups such as a (2-, 4-, 5-, 6- or 7-) benzoxathiolanyloxymethyl group, a group 2- ((2-, 4-, 5-, 6- or 7-) benzoxathiolanyloxy) ethyl, a group l - ((2-, 4-, 5-, 6- or 7-) benzoxathiolanyloxy) ethyl, a group 3- ((2-, 4-, 5-, 6- or 7-) benzoxathiolanyloxy) -propyl, a 2 - ((2-, 4-, 5-, 6- or 7-) benzoxathiolanyloxy) propyl group , a 4- ((2-, 4-, 5-, 6- or 7-) benzoxathiolanyloxy) butyl group, a 5- ((2-, 4-, 5-, β- or 7-) benzoxathiolanyloxy) pentyl group , a group 4 - ((2-, 4-, 5-, 6- or 7-) benzoxathiolanyloxy) pentyl, a group 6 - ((2-, 4-, 5-, 6- or 7-) benzoxathiolanyloxy) hexyl , a 2-methyl-3- ((2-, 4-, 5-, 6- or 7-) benzoxathiolanyloxy) -propyl group, a 1, 1-dimethyl-2- ((2-, 4-, -, 6- or 7-) benzoxathiolanyloxy) ethyl, and a group (2-oxo- (4-, 5-, 6- or 7-) benzoxathiolarnyloxy) -methyl, provided that, in the benzoxathiolane ring, a group oxo pued e to be replaced. Examples of the Cl-Cβ isoquinolyloxy alkyl group can include a group (1-, 3-, 4-, 5-, 6-, 7- or 8-) isoquinolyloxymethyl, a group 2 - ((1-, 3-4) -, 5-, 6-, 7- or 8-) isoquinolyloxy) ethyl, a group 1- ((1-, 3-, 4-, 5-, 6-, 7- or 8-) isoquinolyloxy) ethyl, a Group 3- ((1-, 3-, 4-, 5-, 6-, 7- or 8-) isoquinolyloxy) propyl, a group 2 - ((1-, 3-, 4-, 5-, β- , 7- or 8-) isoquinolyloxy) propyl, a group 4 - ((1-, 3-, 4-, 5-, 6-, 7- or 8-) isoquinolyloxy) butyl, a group 5 - ((1- , 3-, 4-, 5-, 6-, 7- or 8-) isoquinolyloxy) pentyl, a group 4 - ((I-, 3-, 4-, 5-, 6-, 7- or 8- isoquinolyloxy) pentyl, a group 6 - ((1-, 3-, 4-, 5-, 6-, 7- or 8-) isoquinolyloxy) hexyl, a group 2-methyl-3- ((1-, 3 -, 4-, 5-, 6-, 7- or 8-) isoquinolyloxy) propyl, and a group 1, l-dimethyl-2- ((1-, 3-, 4-, 5-, β-, 7 - or 8-) isoquinolyloxy) ethyl. Examples of the Cl-Cβ pyridyloxy alkyl group may include a (2-, 3- or 4-) pyridyloxymethyl group, a 2 - ((2-, 3- or 4-) pyridyloxy) ethyl group, a group l - (( 2-, 3- or 4-) pyridyloxy) ethyl, a 3- ((2-, 3- or 4-) pyridyloxy) propyl group, a 2- ((2-, 3- or 4-) pyridyloxy) propyl group , a 4- ((2-, 3- or 4-) pyridyloxy) butyl group, a 5- ((2-, 3- or 4-) pyridyloxy) pentyl group, a group 4- ((2-, 3- or 4-) pyridyloxy) pentyl, a 6- ((2-, 3- or 4-) pyridyloxy) hexyl group, a 2-methyl-3- ((2-, 3- or 4-) pyridyloxy) propyl group, and a 1, 1-dimethyl-2- ((2-, 3- or 4-) pyridyloxy) ethyl group. Examples of the C1-C6 alkyl dibenzofuryloxy group may include a (1-, 2-, 3- or 4-) dibenzofuryloxyethyl group, a group 2 - ((1-, 2-, 3-, 4-, 5- , 6-, 7- or 8-) dibenzofuryloxy) ethyl, a group 1 - ((1-, 2-, 3- or 4-) dibenzofuryloxy) ethyl, a group 3 - ((1-, 2-, 3- or 4-) dibenzofuryloxy) propyl, a 2 - ((l-, 2-, 3- or 4-) dibenzofuryloxy) propyl group, a 4 - ((l-, 2-, 3- or 4-) dibenzofuryloxy group) butyl, a 5 - ((l-, 2-, 3- or 4-) dibenzofuryloxy) pentyl group, a 4 - ((l-, 2-, 3- or 4-) dibenzofuryloxy) pentyl group, a group 6- ((1-, 2-, 3- or 4-) dibenzofuryloxy) hexyl, a 2-methyl-3- ((1-, 2-, 3- or 4-) dibenzofuryloxy) propyl group, and a group 1, -dimethyl-2- ((1-, 2-, 3- or 4-) dibenzofuryloxy) ethyl. Examples of the Cl-Cβ 2 H-1-benzopyranyloxy alkyl group (wherein, in the 2H-1-benzopyran ring, at least one oxo group can be substituted) can include Cl-C 2 H-1-benzopyranyloxy alkyl groups such as a group (2-, 3-, 4-, 5-, 6-, 7- or 8-) 2H-l-benzopyranyloxymethyl, a group 2- ((2-, 3-, 4-, 5-, 6-, 7- or 8-) 2H-l-benzopyranyloxy) ethyl, a group l - ((2-, 3-, 4-, 5-, β-, 7- or 8-) 2H-l-benzopyranyloxy) ethyl, a group 3- ((2-, 3-, 4-, 5-, 6-, 7- or 8-) 2H-l-benzopyranyloxy) propyl, a group 2 - ((2-, 3-, 4-5 -, 6-, 7- or 8-) 2H-l-benzopyranyloxy) propyl, a group 4- ((2-, 3-, 4-, 5-, 6-, 7- or 8-) 2H-l- benzopyranyloxy) butyl, a group 5- ((2-, 3-, 4-, 5-, 6-, 7- or 8-) 2H-l-benzopyranyloxy) pentyl, a group 4- ((2-, 3- , 4-, 5-, 6-, 7- or 8-) 2H-l-benzopyranyloxy) pentyl, a group 6- ((2-, 3-, 4-, 5-, 6-, 7- or 8- ) 2H-l-benzopyranyloxy) hexyl, a 2-methyl-3- ((2-, 3-, 4-, 5-, 6-, 7- or 8-) 2H-l-benzopyranyloxy) propyl, a group 1, l-dimethyl-2- ((2-, 3-, 4-, 5- , 6-, 7- or 8-) 2H-l-benzopyranyloxy) ethyl, and a group (2-oxo- (3-, 4-, 5-, 6-, 7- or 8-) 2H-l-benzopyranyloxy ) methyl, provided that, in the 2H-1-benzopyran ring, an oxo group can be substituted. Examples of the C 1 -C 6 alkyl benzoisoxazolyloxy group can include a group (3-, 4-, 5-, 6- or 7-) benzoisoxazolyloxymethyl, a group 2 - ((3-, 4-, 5-, 6- or 7) -) benzoisoxazolyloxy) ethyl, a group l - ((3-, 4-, 5-, 6- or 7-) benzoisoxazoliloxi) ethyl, a group 3- ((3-, 4-, 5-, 6- or 7 -) benzoisoxazolyloxy) propyl, a 2- ((3-, 4-, 5-, 6- or 7-) benzoisoxazolyloxy) propyl group, a group 4- ((3-, 4-, 5-, 6- or 7) -) benzoisoxazolyloxy) butyl, a 5- ((3-, 4-, 5-, 6- or 7-) benzoisoxazolyloxy) pentyl group, a group 4- ((3-, 4-, 5-, 6- or 7) -) benzoisoxazolyloxy) -pentyl, a 6- ((3-, 4-, 5-, 6- or 7-) benzoisoxazolyloxy) hexyl group, a 2-methyl-3- ((3-, 4-, 5- , 6- or 7-) benzoisoxazolyloxy) propyl, and a 1, 1-dimethyl-2 - ((3-, 4-, 5-, 6- or 7-) benzoisoxazolyloxy) ethyl group. Examples of the C 1 -C 6 alkyl group benzofurazayloxy may include a (4- or 5-) benzofurazanyloxymethyl group, a 2- ((4- or 5-) benzofurazayloxy) ethyl group, a l- ((4- or 5) group. -) benzof urazaniloxy) ethyl, a group 3 - ((4- or 5-) benzofurazayloxy) propyl, a group 2 - ((4- or 5-) benzofurazayloxy) propyl, a group 4 - ((4- or 5-) benzofurazayloxy) butyl, a 5 - ((4- or 5-) benzofurazayloxy) pentyl group, a 4 - ((4- or 5-) benzofurazayloxy) pentyl group, a group 6 - ((4- or 5-) benzofurazayloxy) hexyl, m group 2-methyl-3 - ((4- or 5-) benzofurazayloxy) propyl, and a group 1, l-dimethyl-2- ((4- or 5-) benzof urazanyloxy) ethyl. Examples of the Cl-Cβ quinoxalyloxy alkyl group may include a (2-, 5- or 6-) quinoxalyloxymethyl group, a 2- ((2-, 5- or 6-) quinoxalyloxy) ethyl group, a group l- (( 2-, 5- or 6-) quinoxalyloxy) ethyl, a 3- ((2-, 5- or 6-) quinoxalyloxy) propyl group, a 2- ((2-, 5- or 6-) quinoxalyloxy) propyl group , a 4- ((2-, 5- or 6-) quinoxalyloxy) butyl group, a 5- ((2-, 5- or 6-) quinoxalyloxy) pentyl group, a group 4- ((2-, 5- or 6-) quinoxalyloxy) pentyl, a 6- ((2-, 5- or 6-) quinoxalyloxy) hexyl group, a 2-methyl-3- ((2-, 5- or 6-) quinoxalyloxy) propyl group, and a 1, 1-dimethyl-2- ((2-, 5- or 6-) quinoxalyloxy) ethyl group. The examples of the C2-C10 alkenyl group phenyl [wherein, in the phenyl ring, at least one selected from the following groups can be substituted: a halogen atom, a C1-C4 alkylenedioxy group, a C1-C6 alkylthio group, a benzoyl group, a cyano group, a nitro group, a C2-C6 alkanoyloxy group, an amino group which may have C1-C6 alkyl groups as a substituent, a hydroxyl group, a C1-C6 alkoxy phenyl group, a phenoxy group, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cß alkoxy group substituted or unsubstituted with halogen), may include the C2-C6 alkenyl group phenyl described above (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), as well as alkenyl groups containing up to 10 carb atoms ono and having 1 to 3 double bonds, wherein, in the C2-C10 alkenyl group, 1 or 2 phenyl groups can be substituted, such as a 2-n-pentyl-3-phenyl-2-propenyl group, a group 9-phenyl-2-nonenyl, a 10-phenyl-2-decenyl group, a 8-phenyl-1,3-octadienyl group, a 9-phenyl-1,3,5-nonatrienyl group, a group 10-2, 4, β-decatrienyl, a 3- (4-methylthiophenyl) -2-propenyl group, a 3- (3-methylthiophenyl) -2-propenyl group, a 3- (2-methylthiophenyl) -2-propenyl group, a group 3- (3, 4-dimethylthiophenyl) -2-propenyl, a 3- (3,4,5-trimethylthiophenyl) -2-propenyl group, a 3- (4-benzoyl) -2-propenyl group, a 3- group (3-benzoyl) -2-propenyl, a 3- (2-benzoyl) -2-propenyl group, a 3- (3,4-dibenzoyl) -2-propenyl group, a 3- (2, 4, 6) group -tribenzoyl) -2-propenyl, a 3- (4-cyanophenyl) -2-propenyl group, a 3- (3-cyanophenyl) -2-propenyl group, a 3- (2-cyanophenyl) -2-propenyl group, a 3- (3,4-dicyanophenyl) -2-propenyl group, a 3- (2,4,6-tricono-phenyl) -2-propenyl group, a 3- (4-acetyloxyphenyl) -2-propenyl group, a 3- (4-acetyloxy-3-methoxyphenyl) -2-propenyl group, a 3- (3-acetyloxyphenyl) -2-propenyl group, a 3- group (2-acetyloxyphenyl) -2-propenyl, a 3- (3,4-diacetyloxyphenyl) -2-propenyl group, a 3- (2,4,6-triacetyloxyphenyl) -2-propenyl group, a 3- (4) group -dimethylaminophenyl) -2-propenyl, a 3- (4-dimethylaminophenyl) -2-propenyl group, a 3- (3-methylaminophenyl) -2-propenyl group, a 3- (2- (N-methyl-N- ethylamino) phenyl) -2-propenyl, a 3- (2,4-dimethylaminophenyl) -2-propenyl group, a 3- (2,4,6-tri (dimethylamino) phenyl) -2-propenyl group, a group 3 - (2-hydroxyphenyl) -2-propenyl, a 3- (3-hydroxyphenyl) -2-propenyl group, a 3- (4-hydroxyphenyl) -2-propenyl group, a 3- (3,5-dimethyl-) group 4-hydroxyphenyl) -2-propenyl, a 3- (3-methoxy-4-hydroxyphenyl) -2-propenyl group, a 3- (2-hydroxyphenyl) -2-propenyl group, a 3- (4-benzyloxyphenyl) group -2-propenyl, a 3- (4-benzyloxyphenyl) -2-propenyl group, a 3- (2-benzyloxy) group nil) -2-propenyl, a 3- (2,4,6-tribenzyloxyphenyl) -2-propenyl group, a 3- (3,4-dibenzyloxyphenyl) -2-propenyl group, a 3- (4-phenoxyphenyl) group -2-propenyl, a 3- (3-phenoxyphenyl) -2-propenyl group, a 3- (2-phenoxyphenyl) -2-propenyl group, a 3- (2,4-diphenoxyphenyl) -2-propenyl group, a 3- (2,4,6-trifenoxyphenyl) -2-propenyl group, a 3- (3,4-methylenedioxyphenyl) -2-propenyl group, a 3- (2,3-ethylenedioxyphenyl) -2-propenyl group, and a 3- (3,4-ethylenedioxyphenyl) -2-propenyl group. The C2-C10 alkenyl group phenyl above includes both a trans form and a cis form. In the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the following groups can be substituted: a halogen atom, the C1-C4 alkylenedioxy group described above, the C1-C6 alkylthio group described above, benzoyl group, cyano group, nitro group, the C2-C6 alkanoyloxy group described above, the amino group described above which may have a C1-C6 alkyl group as a substituent, hydroxyl group, the C1-C6 alkoxy phenyl group described above , phenoxy group, the substituted or unsubstituted C1-C6 alkyl group with halogen described above, and the substituted or unsubstituted C1-C6 alkoxy group with halogen described above. In a case where the substituent is a C1-C4 alkylenedioxy group, 1 or 2 groups are preferably substituted on the phenyl ring. Examples of the C2-C6 alkenyl group naphthyl may include alkenyl groups containing 2 to 6 carbon atoms and having 1 to 3 double bonds, wherein a naphthyl group is substituted, such as a 2- (1- or 2-) ) naphthylvinyl, a 3- (l- or 2-) naphthyl-2-propenyl group, a 3- (l- or 2-) naphthyl-2-methyl-2-propenyl group, a 4- (l- or 2) group -) naphthyl-2-butenyl, a 4- (l- or 2-) naphthyl-3-butenyl group, a 4- (l- or 2-) naphthyl-1,3-butadienyl group, a 5- (1 group - or 2-) naphthyl-1,3-pentadienyl, a 6- (l- or 2-) naphthyl-3-hexadienyl group, a 6- (l- or 2-) naphthyl-2-hexenyl group, a group 5 - (1-) 2- naphthyl-2-pentenyl, and a 6- (1-- or 2-) naphthyl-1,3,5-hexadienyl group. The above C2-Cβ naphthyl alkenyl group includes both a trans form and a cis form. Examples of the C2-C6 benzothienyl alkenyl group may include alkenyl groups containing 2 to 6 carbon atoms and having 1 to 3 double bonds, wherein a benzothienyl group is substituted, such as a 2- (2-, 3-) group -, 4-, 5-, 6- or 7-) benzothienylvinyl, a 3- (2-, 3-, 4-, 5-, 6- or 7-) benzothienyl-2-propenyl group, a group 3- ( 2-, 3-, 4-, 5-, 6- or 7-) benzothienyl-2-methyl-2-propenyl, a group 4- (2-, 3-, 4-, 5-, 6- or 7- ) benzothienyl-2-butenyl, a 4- (2-, 3-, 4-, 5-, 6- or 7-) benzothienyl-3-butenyl group, a group 4- (2-, 3-, 4-, 5-, ß- or 7-) benzothienyl-1,3-butadienyl, a 5- (2-, 3-, 4-, 5-, ß- or 7-) benzothienyl-1,3-pentadienyl group, a group 6- (2-, 3-, 4-, 5-, 6- or 7-) benzothienyl-l, 3-hexadienyl, a group 6- (2-, 3-, 4-, 5-, β- or 7 -) benzothienyl-2-hexenyl, a 5- (2-, 3-, 4-, 5-, 6- or 7-) benzothienyl-2-pentenyl group, and a β- (2-, 3-, 4-) group -, 5-, 6- or 7-) benzothienyl-1,3,5-hexatrienyl. The above C2-C6 benzothienyl alkenyl group includes both a trans form and a cis form. Examples of the C2-C6 alkenyl group benzothiazolyl [wherein, in the benzothiazole ring, at least one Cl-Cß alkyl group can be substituted] can include alkenyl groups containing 2 to 6 carbon atoms and having 1 to 3 double bonds , wherein a benzothiazolyl group is substituted, such as a 2- (2-, 4-, 5-, 6- or 7-) benzothiazolylvinyl group, a 3- (2-, 4-, 5-, 6- 7-) benzothiazolyl-2-propenyl, a 3- (2-, 4-, 5-, 6- or 7-) benzothiazolyl-2-methyl-2-propenyl group, a group 4- (2-, 4-, 5-, 6- or 7-) benzothiazolyl-2-butenyl, a 4- (2-, 4-, 5-, 6- or 7-) benzothiazolyl-3-butenyl group, a 4- (2-, 4- group -, 5-, ß- or 7-) benzothiazolyl-1,3-butadienyl, a 5- (2-, 4-, 5-, 6- or 7-) benzothiazolyl-1,3-pentadienyl group, a group 6 - (2-, 4-, 5-, 6- or 7-) benzothiazolyl-1,3-hexadienyl, a 6- (2-, 4-, 5-, 6- or 7-) benzothiazolyl-2-hexenyl group , a 5- (2-, 4-, 5-, 6- or 7-) benzothiazolyl-2-pentenyl group, a 6- (2-, 4-, 5-, 6- or 7-) benzothiazole group il-l, 3, 5-hexadienyl, a 3- (2-methyl-5-benzothiazolyl) -2-propenyl group, a 3- (2-ethyl-4-benzothiazol) -2-propenyl group, a 3- group (2-n-propyl-6-benzothiazolyl) -2-propenyl, a 3- (2-n-butyl-7-benzothiazolyl) -2-propenyl group, a 3- (4-n-pentyl-5-benzothiazolyl group ) -2-propenyl, a 3- (5-n-hexyl-2-benzothiazolyl) -2-propenyl group, a 3- (2,4-dimethyl-5-benzothiazolyl) -2-propenyl group, and a group 3 - (2, 4, 5-trimethyl-7-benzothiazolyl) -2-propenyl. The above C2-C6 alkenyl benzothiazolyl group includes both a trans form and a cis form. Examples of the C1-C6 alkyl group phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a piperidinyl group (wherein, in the piperidine ring, at least one phenoxy group can be substituted [wherein, in the phenyl ring, at least one selected from the group consisting of one atom of halogen, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-C6 alkoxy group substituted or unsubstituted by halogen can be substituted]) and a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-C6 alkoxy group substituted or unsubstituted by halogen can be substituted) is substituted], can include C1 alkyl groups -C6 phenyl such as a 4- (1-piperidyl) benzyl group, a 2,4-di (4-piperidyl) benzyl group, a 2, 4,6-tri (2-piperidyl) benzyl group, a 4- group (4- (4-trifluoromethoxyphenoxy) -1-piperidyl) benzyl, a 4- (4- (4-trifluoromethyl) group enoxi) -1-piperidyl) benzyl, a 4- (4- (4-chlorophenoxy) -1-piperidyl) benzyl group, a 4- (4- (3,4-di (trifluoromethoxy) phenoxy) -1-piperidyl group ) benzyl, a 4- (4- (2,4,6-tri (trifluoromethyl) phenoxy) -1-piperidyl) benzyl group, a 4- (4- (2,4-dichlorophenoxy) -1-piperidyl) benzyl group , a 4- (4- (2,4,6-trifluorophenoxy) -1-piperidyl) benzyl group, a 3- (2,4-diphenoxy-3-piperidyl) benzyl group, a 2- (1, 2, 3-Triphenoxy-4-piperidyl) benzyl, a 4- (4-trifluoromethoxyphenoxy) benzyl group, a 4- (4-trifluoromethylphenoxy) benzyl group, a 4- (4-chlorophenoxy) benzyl group, a 4- (2 group, 4-dichlorophenoxy) benzyl, a 4- (3,4,5-trifluorophenoxy) benzyl group, a 4- (3-methylphenoxy) benzyl group, a 4- (2-methoxyphenoxy) benzyl group, a 4- (2 group, 4-dimethylphenoxy) benzyl, a 4- (3,4-dimethoxyphenoxy) benzyl group, a 4- (2,4,6-trimethylphenoxy) benzyl group, a 4- (3,4,5-trimethoxyphenoxy) benzyl group, a Group 2, 4-diphenoxybenzyl, a 2, 4,6-trifenoxibenzyl group, yu n 2-phenoxy-4- (1-piperidyl) benzyl group [wherein, in the phenyl ring, 1 to 3 groups selected from the group consisting of the piperidinyl group described above (wherein, in the piperidine ring, 1 to 3 groups Phenoxy can be substituted [wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-6 alkoxy group C6 substituted or unsubstituted with halogen can be substituted]) and the phenoxy group described above (wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) are substituted]. Examples of the Cl-Cβ-biphenyl alkyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen, and an alkoxy Cl group -Cβ substituted or unsubstituted with halogen can be substituted] can include Cl-Cß alkyl groups in which 2 phenyl groups are substituted [wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consists of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], such as a diphenylmethyl group, a group 2, 2- diphenylethyl, a 1, 1-diphenylethyl group, a 3, 3-diphenylpropyl group, a 2,3-diphenylpropyl group, a 4,4-diphenylbutyl group, a 5,5-diphenylpentyl group, a 4,5-diphenylpentyl group, a 6,6-diphenylhexyl group, a 2-methyl-3,3-diphenyl group propyl, a 1, 1-dimethyl-2,2-diphenylethyl group, a di (4-chlorophenyl) methyl group, a di (4-trifluoromethoxyphenyl) methyl group, a di (4-trifluoromethylphenyl) methyl group, a di ( 3-methoxyphenyl) methyl, a di (2,4-dichlorophenyl) methyl group, a di (2-methylphenyl) methyl group, a di (2,4,6-trifluorophenyl) methyl group, a di (3, 4) group dimethoxyphenyl) methyl, a di (2,4,6-trimethoxyphenyl) methyl group, a di (3,4-dimethylphenyl) methyl group, a di (2,4,6-trimethylphenyl) methyl group, and a l- group ( 4-trifluoromethoxyphenyl) -1- (4-chlorophenyl) methyl. Examples of the phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a C1-C4 alkylenedioxy group, a phenyl group, a C1-C6 alkoxycarbonyl group, a hydroxyl group, and a phenoxy group ( wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted), substituted] may include phenyl groups such as a 4-biphenyl, a 4-tert-butoxycarbonylphenyl group, a 4-ethoxycarbonylphenyl group, a 2-biphenyl group, a 4-hydroxyphenyl group, a 4- (4-) group chlorophenoxy) phenyl, a 2,3-ethylenedioxyphenyl group, a 3-biphenyl group, a 3-tert-butoxycarbonylphenyl group, a 3-methoxycarbonylphenyl group, a 2,4-diphenylphenyl group, a 3-hydroxyphenyl group, a 4- group (4-trifluoromethoxyphenoxy) phenyl, a 2,3-methylenedioxyphenyl group, a group 2, 4, 6 triphenyl, a 2-tert-butoxycarbonyl-f-enyl group, a 2-propoxycarbonyl-f-enyl group, a 2-n-pentyloxy-enyl group, a 2-hydroxy-enyl group, a 4- (4-trifluoromethyl-enoxy) -phenyl group, a group 3 , 4-ethylenedioxyphenyl, a 2, 4,6-trihydroxyphenyl group, a 4-n-hexyloxycarbonylfamilyl group, a 2,4-diethoxycarbonylphenyl group, a 2-biphenyl group, a 3, 4-dihydroxyphenyl group, a 4- (2, 4-di chlorofenoxi) phenyl group, a 3- (2, 4, ß-trif luorofenoxi) phenyl group, a 2, 4,6-trietoxycarbonylfyl group, a 3- (2-methyl) group enoxi) phenyl, a 4- (3-methyl-enoxy) -phenyl group, a 2- (4-methyl-enoxy) -phenyl group, a 3- (2,3-dimethyl-enoxy) -phenyl group, a 4- (2, 4) group , 5-trimethyl-enoxy) phenyl, a 3- (2-methoxy-enoxy) -phenyl group, a 4- (3-methoxy-enoxy) -phenyl group, a 2- (4-methoxyphenoxy) phenyl group, a 3- (3,4-dimethoxy enoxi) phenyl group, a 4 - (2, 4, 6- t rimet oxifenoxi) phenyl group, a 2- group phenoxy-4-ethoxycarbonylphenyl, and a 2-phenyl-3-f-enoxyphenyl group [wherein, in the phenyl ring, 1 to 3 groups selected from the group consisting of the C1-C4 alkylenedioxy group described above, the phenyl group described above , the C1-C6 alkoxycarbonyl group described above, hydroxyl group, and the phenoxy group described above (wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen can be substituted), are substituted].

Examples of the benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom and a C1-C6 alkyl group can be substituted] can include benzofuryl groups such as a group (2-, 3-, 4-, 5-, 6- or 7-) benzofuryl, a 5-chloro-7-benzofuryl group, a 5-methyl-7-benzofuryl group, a 4-iodo-6-benzofuryl group, a 6-chloro group -ethyl-7-benzofuryl, a 6-bromo-5-benzofuryl group, a 7-n-propyl-4-benzofuryl group, a 7-fluoro-2-benzofuryl group, a 4-n-butyl-2-benzofuryl group , a 2, 5-dichloro-7-benzofuryl group, a 5,6-dimethyl-7-benzofuryl group, a 3, 5,6- trifluoro-2-benzofuryl group, a 3, 4, 5-trimethyl-3 group benzofuryl, a 5-chloro-4-methyl-7-benzofuryl group, and a 5-methyl-3-fluoro-8-benzofuryl group, provided that, in the benzofuran ring, 1 to 3 groups selected from the group consists of the halogen atom described above and the C1-C6 alkyl group described above may be substituted. Examples of the benzothiazolinyl group [wherein, in the benzothiazoline ring, at least one oxo group can be substituted] can include benzothiazolinyl group such as a (2-, 4-, 5-, 6- or 7-) benzothiazolyl group and a 2-oxo-6-benzothiazolyl group, provided that, in the benzothiazoline ring, an oxo group can be substituted. Examples of the benzothienyl group [wherein, in the benzothiophene ring, at least one halogen atom can be substituted] can include benzothienyl groups such as a group (2-, 3-, 4-, 5-, 6- or 7-) benzothienyl, a 5- fluoro-4-benzothienyl group, a 6-fluoro-2-benzothienyl group, a 2-chloro-3-benzothienyl group, a 3-bromo-6-benzothienyl group, a 4-iodo-5 group benzothienyl, a 2, 4,6-trichloro-7-benzothienyl group, and a 4,5-difluoro-2-benzothienyl group, provided that, in the benzothiophene ring, 1 to 3 halogen atoms can be substituted. Examples of the 1, 2, 3, 4-tetrahydroquinolyl group (wherein, in ring 1, 2, 3, -tetrahydroquinoline, at least one selected from the group consisting of an oxo group and a Cl-Cß alkyl group can be substituted) may include 1, 2, 3, 4-tetrahydroquinolyl groups such as a group (1-, 2-, 3-, 4-, 5-, 6-, 7- or 8-) 1, 2, 3, 4 -tetrahydroquinolyl, a 2-oxo- (l-, 3-, 4-, 5-, 6-, 7- or 8-) l, 2,3,4-tetrahydroquinolyl group, a 2, 4-dioxo- group ( 1-, 3-, 5-, 6-, 7- or 8-) 1, 2, 3, 4-tetrahydroquinolyl, a 3-oxo- (l-, 2-, 4-, 5-, 6-, 7- or 8-) 1, 2, 3, 4-tetrahydroquinolyl, a l-methyl-2-oxo-5-l, 2,3,4-tetrahydroquinolyl group, a 2-methyl-1-1.2 group, 3,4-tetrahydroquinolyl, a 3-ethyl-2-l, 2,3,4-tetrahydroquinolyl group, a 4-n-propyl-3-l, 2,3,4-tetrahydroquinolyl group, a 5-n- group butyl-4-1,2,3,4-tetrahydroquinolyl, a 6-n-pentyl-5-l, 2,3,4-tetrahydroquinolyl group, a 7-n-hexyl-β-l, 2,3 group 4-tetrahydroquinolyl, a group 8-methyl-7-l, 2,3,4-tetrahydroquinolyl, a g 4,6-dimethyl-5-1, 2, 3, 4-tetrahydroquinolyl, and a 5,6,7-trimethyl-4-1, 2, 3, 4-tetrahydroquinolyl group, provided, in the ring 1, 2, 3, 4-tetrahydroquinoline, 1 to 3 groups selected from the group consisting of an oxo group and Cl-Cß alkyl group described above can be substituted. Examples of the 1,2-dihydrohydroquinolyl group (wherein, in the 1,2-dihydrohydroquinoline ring, at least one oxo group can be substituted) can include 1,2-dihydrohydroquinolyl groups such as a group (1-, 2-, 3-, 4-, 5-, ß-, 7- or 8-) 1, 2-dihydrohydroquinolyl and a 2-oxo- (l-, 3-, 4-, 5-, 6-, 7- or 8- group -) 1,2-dihydrohydroquinolyl, provided that, in the 1,2-dihydrohydroquinoline ring, an oxo group can be substituted. Examples of the 1, 2, 3, 4-tetrahydro-quinazolinyl group [wherein, in the 1, 2, 3, 4-tetrahydroquinazoline ring, at least one selected from the group consisting of an oxo group and an alkyl group Cl- Cβ can be substituted] can include 1,2,3,4-tetrahydroquinazolinyl groups such as a group (1-, 2-, 3-, 4-, 5-, β-, 7- or 8-) 1, 2, 3,4-tetrahydroquinazolinyl, a 2-oxo- (l-, 3-, 4-, 5-, 6-, 7- or 8-) 1,2,3,4-tetrahydroquinazolinyl group, a 4-oxo- (1-- 2) group -, 3-, 5-, 6-, 7- or 8-) l, 2,3,4-tetrahydroquinazolinyl, a 2,4-dioxo- (l-, 3-, 5-, β-, 7- or 8-) 1, 2,3,4-tetrahydroquinazolinyl, a l-methyl-2,4-dioxo- (3-, 5-, 6-, 7- or 8-) 1,2,3- tetrahydroquinazolinyl, a 3-ethyl-2,4-dioxo- (1-, 5-, 6-, 7- or 8-) 1,2,3,4-tetrahydroquinazolinyl group, a 1, 3-dimethyl-2 group, 4-dioxo- (5-, 6-, 7- or 8-) 1,2,3,4-tetrahydroquinazolinyl, an ln-propyl-5-methyl-2-oxo- (3-, 4-, β- , 7- or 8-) 1, 2, 3, 4-tetrahydroquinazolinyl, an ln-butyl-β-methyl-4-oxo- (2-, 3-, 5-, 7- or 8-) 1, 2 group , 3, 4- tetrahydroquinazolinyl, an ln-pentyl-7-methyl-2-oxo- (3-, 4-, 5-, 6- or 8-) 1, 2, 3, 4-tetrahydroquinazolinyl group, and a group ln-hexyl-8-methyl-2,4-dioxo- (3-, 5-, 6- or 7-) 1, 2, 3, 4-tetrahydroquinazolinyl, provided that, in ring 1, 2, 3 , 4-tetrahydroquinazoline, 1 to 4 groups selected from the group consisting of of an oxo group and the Cl-Cß alkyl group described above can be substituted. Examples of the benzothienyl substituted Cl-Cß alkyl group [wherein, in the benzothiophene ring, at least one halogen atom can be substituted] can include benzothienyl substituted Cl-Cß alkyl groups such as a 2-benzothienylmethyl group, a 3-benzothienylmethyl group, a 4-benzothienylmethyl group, a 5-benzothienylmethyl group, a 6-benzothienylmethyl group, a 7-benzothienylmethyl group, a 2- (2-benzothienyl) ethyl group, a 3- (2-benzothienyl) propyl group , a 4- (2-benzothienyl) butyl group, a 5- (2-benzothienyl) -tyl group, a 6- (2-benzothienyl) hexyl group, a 5-chloro-3-benzothienylmethyl group, a group 3, 4- dibromo-2-benzothienylmethyl, and a 4, 5,6-trichloro-2-benzothienylmethyl group, provided that, in the benzothiophene ring, 1 to 3 halogen atoms can be substituted]. Examples of the C1-Cß alkyl group substituted with naphthyl may include a 1-naphthylmethyl group, a 2-naphthylmethyl group, a 2- (1-naphthyl) ethyl group, a l- (2-naphthyl) ethyl group, a 3- (1-naphthyl) propyl group, a 3- (2-naphthyl) propyl group, a 4- (1-naphthyl) butyl group, a 4- (2-naphthyl) butyl group, a 5- (1) group -naphthyl) pentyl, a 5- (2-naphthyl) pentyl group, a 6- (l-naphthyl) hexyl group, and a β- (2-naphthyl) hexyl group. Examples of the pyridyl substituted Cl-Cβ alkyl group [wherein, in the pyrridine ring, at least one halogen atom can be substituted] can include C1-Cβ alkyl groups substituted with pyridyl such as a 2-pyridylmethyl group, a group 3-pyridylmethyl, a 4-pyridylmethyl group, a 2- (2-pyridyl) ethyl group, a 2- (3-pyridyl) ethyl group, a 2- (4-pyridyl) ethyl group, a 3- (2-) group pyridyl) propyl, a 3- (3-pyridyl) propyl group, a 3- (4-pyridyl) propyl group, a 4- (2-pyridyl) utilo group, a 4- (3-pyridyl) utilo group, a group 4- (4-pyridyl) butyl, a 5- (2-pyridyl) pentyl group, a 5- (3-pyridyl) pentyl group, a 5- (4-pyridyl) pentyl group, a 6- (2-pyridyl) group ) hexyl, a 6- (3-pyridyl) hexyl group, a 6- (4-pyridyl) hexyl group, a 2-chloro-3-pyridylmethyl group, a 3-bromo-2-pyridylmethyl group, a 4-fluoro group -2-pyridylmethyl, a 2- (2-chloro-4-pyridyl) ethyl group, a 2- (3-chloro-5-pyridyl) ethyl group, a 2- (4-iodo-3-pyridyl) ethyl group , a 3- (2-bromo-5-pyridyl) propyl group, a 3- (3-fluoro-4-pyridyl) propyl group, a 3- (4-chloro-2-pyridyl) propyl group, a 4- group (2-iodo-5-pyridyl) butyl, a 4- (3-bromo-5-pyridyl) butyl group, a 4- (4-chloro-3-pyridyl) butyl group, a 5- (2-chloro) group 5- pyridyl) pentyl, a 5- (3-fluoro-2-pyridyl) pentyl group, a 5- (4-bromo-2-pyridyl) pentyl group, a 6- (2-chloro-5-pyridyl) hexyl group , a 6- (3-fluoro-4-pyridyl) hexyl group, a 6- (4-bromo-2-pyridyl) hexyl group, a (2,6-dichloro-4-pyridyl) methyl group, and a group ( 2, 3, 4-trichloro-6-pyridyl) methyl, provided that, in the pyridine ring, 1 to 3 halogen atoms can be substituted as substituents. Examples of the C 1 -C 6 alkyl group substituted with furyl [wherein, in the furan ring, at least one nitro group can be substituted] can include C 1 -C 6 alkyl groups substituted with furyl such as a 2-furylmethyl group, a 3-furylmethyl group, a 2- (2-furyl) ethyl group, a 3- (2-furyl) propyl group, a 3- (3-furyl) propyl group, a 4- (2-furyl) butyl group, a 4- (3-furyl) butyl group, a 5- (2) group -furyl) pentyl, a 5- (3-furyl) pentyl group, a 6- (2-furyl) hexyl group, a 6- (3-furyl) hexyl group, a 5-nitro-2-furylmethyl group, a group 5-Nitro-3-furylmethyl, a 2- (5-nitro-2-furyl) ethyl group, a 3- (5-nitro-2-furyl) propyl group, a 4- (5-nitro-2-furyl) group Butyl, a 4- (5-nitro-3-furyl) butyl group, a 5- (5-nitro-2-furyl) pentyl group, a group - (5-nitro-3-furyl) pentyl, a 6- (5-nitro-2-furyl) hexyl group, a 6- (5-nitro-3-furyl) hexyl group, a group (4, 5-dinitro-2-furyl) ethyl, and a (2,4,5-trinitro-3-furyl) methyl group, provided that, in the furan ring, 1 to 3 nitro groups can be substituted as substituents Examples of the thienyl substituted C1-C6 alkyl group [wherein, in the thiophene ring, at least one halogen atom can be substituted] can include Cl-Cß alkyl groups substituted with thienyl such as a 2-thienylmethyl group, a group 3-thienylmethyl, a 2- (2-thienyl) ethyl group, a 3- (2-thienyl) propyl group, a 3- (3-thienyl) propyl group, a 4- (2-thienyl) butyl group, a group 4- (3-thienyl) butyl, a 5- (2-thienyl) pentyl group, a 5- (3-thienyl) pentyl group, a 6- (2-thienyl) hexyl group, a 6- (3-thienyl group hexyl, a 5-chloro-2-thienylmethyl group, a 5-chloro-3-thienylmethyl group, a 2- (4-bromo-2-thienyl) ethyl group, a 3- (3-fluoro-2-thienyl) group ) propyl, a 4- (5-iodo-2-thienyl) butyl group, a 4- (4-chloro-3-thienyl) butyl group, a 5- (3-chloro-2-thienyl) pentyl group, a group 5- (2-chloro-3-thienyl) pentyl, a 6- (3-chloro-2-thienyl) hexyl group, a 6- (5-chloro-3-thienyl) hexyl group, a group (4, 5) dichloro-2-thienyl) methyl, and a group (2, 4, 5-trichloro-3) -thienyl) methyl, provided that, in the thiophene ring, 1 to 3 halogen atoms can be substituted as substituents. Examples of the phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom and a C 1 -C 6 alkyl group substituted or unsubstituted with halogen can be substituted) can include a phenyl group, a 2-fluorophenyl group, a 3-fluorophenyl group, a 4-fluorophenyl group, a 2-chlorophenyl group, a 3-chlorophenyl group, a 4-chlorophenyl group, a 2-bromophenyl group, a 3-bromophenyl group, a group 4-bromophenyl, a 2-iodophenyl group, a 3-iodophenyl group, a 4-iodophenyl group, a 2,3-difluorophenyl group, a 3,4-difluorophenyl group, a 3, 5-difluorophenyl group, a group 2, 4-difluorophenyl, a 2,6-difluorophenyl group, a 2,3-dichlorophenyl group, a 3,4-dichlorophenyl group, a 3,5-dichlorophenyl group, a 2,4-dichlorophenyl group, a 2,6- group dichlorophenyl, a 3, 4, 5-trifluorophenyl group, a 3, 4, 5-trichlorophenyl group, a 2,4,6-trifluorophenyl group, a 2, 4,6-trichlorophenyl group, a 2-fluoro-4- group bromof enyl, a 4-chloro-3-fluorophenyl group, a 2,3,4-trichlorophenyl group, a 3, 4, 5-trifluorophenyl group, a 2, 3, 4, 5, 6-pentafluorophenyl group, a group 2, 4,6-trimethylphenyl, a 4-n-butylphenyl group, a 2-dimethylphenyl group, a 2,3-dimethylphenyl group, a 2,6-dimethylphenyl group, a 3,5-dimethylphenyl group, a 2, 5 group -dimethylphenyl, a 3,5-ditrifluoromethylphenyl group, a 3-methyl-4-fluorophenyl group, a 4-bromo-3-trifluoromethylphenyl group, a 2-methylphenyl group, a 3-methylphenyl group, a 4-methylphenyl group, a 2-methyl-3-chlorophenyl group, a 3-methyl-4-chlorophenyl group, a 2-chloro-4-methylphenyl group, a 2-methyl-3-fluorophenyl group, a 2-trifluoromethylphenyl group, a 3-trifluoromethylphenyl group , a 4-trifluoromethylphenyl group, a 2-pentafluoroethylphenyl group, a 3-pentafluoroethylphenyl group, a 4-pentafluoroethylphenyl group, a 2-isopropylphenyl group, a 3-isopropylphenyl group, a 4-isopropylphenyl group, a 2-tert-butylphenyl group , a 3-tert-butylfe group nyl, a 4- tert-butylphenyl group, a 2-sec-butylphenyl group, a 3-sec-butylphenyl group, a 4-sec-butylphenyl group, a 2-n-heptafluoropropylphenyl group, a 3-n-heptafluoropropylphenyl group, a 4-n-heptafluoropropylphenyl group, a 4-n-pentylphenyl group, a 4-n-hexylphenyl group, a 2,3,4-trifluorophenyl group, and a 2,4,6-trifluorophenyl group. Examples of the thiazolyl-substituted C1-C6 alkyl group [wherein, in the thiazole ring, at least one selected from the group consisting of a C1-C6 alkyl group and a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom and a C1-C6 alkyl group substituted or unsubstituted with halogen can be substituted) can be substituted] can include thiazolyl substituted C1-C6 alkyl groups such as a group 4 -thiazolylmethyl, a 5-thiazolylmethyl group, a 2-methyl-4-thiazolylmethyl group, a 2-methyl-5-thiazolylmethyl group, a 2,5-dimethyl-4-thiazolylmethyl group, a 2, 4-dimethyl-5 group -thiazolylmethyl, a 2-methyl-5-phenyl-4-thiazolylmethyl group, a 2-methyl-4-phenyl-5-thiazolylmethyl group, a 2-phenyl-4-thiazolylmethyl group, a 2-phenyl-5-thiazolylmethyl group , a 2-phenyl-5-methyl-4-thiazolylmethyl group, a 2-phenyl-4-methyl-5-thiazolylmethyl group, a 2-methyl-5- (2-fluorophenyl) -4-thiazolylmethyl group, a group 2 -methyl-4- (2-fluorophenyl) -5-thiazolylmethyl, a 2- (2-chlorophenyl) -4-thiazolylmethyl group, a 2- (2-bromophenyl) -5- thiazolylmethyl group, a 2- (2-) group fluorophenyl) -5-methyl-4-thiazolylmethyl, a 2- (2-fluorophenyl) -4-m group ethyl-5-thiazolylmethyl, a 2-methyl-5- (3-iodophenyl) -4-thiazolylmethyl group, a 2-methyl-4- (3-fluorophenyl) -5-thiazolylmethyl group, a '2- (2, 3-difluorophenyl) -4-thiazolylmethyl, a 2- (3-fluorophenyl) -5-thiazolylmethyl group, a 2- (3-fluorophenyl) -5-methyl-4-thiazolylmethyl group, a 2- (3-fluorophenyl) group) -4-methyl-5-thiazolylmethyl, a 2-methyl-5- (2,4,6-trichlorophenyl) -4-thiazolylmethyl group, a 2-methyl-4- (2, 3, 4, 5, 6- pentafluorophenyl) -5-thiazolylmethyl, a 2- (4-fluorophenyl) -4-thiazolylmethyl group, a 4- (2-fluorophenyl) -5-thiazolylmethyl group, a 2- (4-fluorophenyl) -5-methyl-4 group -thiazolylmethyl, a 2- (4-fluorophenyl) -4-methyl-5-thiazolylmethyl group, a 2-methyl-5- (2-chlorophenyl) -4-thiazolylmethyl group, a 2-methyl-4- (2-) group chlorophenyl) -5-thiazolylmethyl, a 2- (2-chlorophenyl) -4-thiazolylmethyl group, a 2- (2-chlorophenyl) -5-thiazolylmethyl group, a 2- (2-chlorophenyl) -5-methyl-4 group -thiazolylmethyl, a 2- (2-chlorophenyl) -4-methyl-5-thiazolylmethyl group, a 2- group methyl-5- (3-chlorophenyl) -4-thiazolylmethyl, a 2-methyl-4- (3-chlorophenyl) -5-thiazolylmethyl group, a 2- (3-chlorophenyl) -4-thiazolylmethyl group, a 2- group (2-fluorophenyl) -5-thiazolylmethyl, a 2- (3-chlorophenyl) -5-methyl-4-thiazolylmethyl group, a 2- (3-chlorophenyl) -4-methyl-5-thiazolylmethyl group, a 2- group methyl-5- (4-chlorophenyl) -4-thiazolylmethyl, a 2-methyl-4- (4-chlorophenyl) -5-thiazolylmethyl group, a 2- (4-chlorophenyl) -4- thiazolylmethyl group, a 2- group (4-chlorophenyl) -5-thiazolylmethyl, a 2- (4-chlorophenyl) -5-methyl-4-thiazolylmethyl group, a 2- (4-chlorophenyl) -4-methyl-5-thiazolylmethyl group, a 2- group (2- thiazolyl) ethyl, a 2- (4-thiazolyl) ethyl group, a 2- (5-thiazolyl) ethyl group, a 2- (2-methyl-4-thiazolyl) ethyl group, a 2- (2) group -methyl-5-thiazolyl) ethyl, a 2- (2,5-dimethyl-4-thiazolyl) ethyl group, a 2- (2,4-dimethyl-5-thiazolyl) ethyl group, a 2- (2-) group methyl-5-phenyl-4-thiazolyl) ethyl, a 2- (2-methyl-4-phenyl-5-thiazolyl) ethyl group, a 2- (2-phenyl-4-thiaz) group olyl) ethyl, a 2- (2-phenyl-5-thiazolyl) ethyl group, a 2- (2-phenyl-5-methyl-4-thiazolyl) ethyl group, a 3- (2-thiazolyl) propyl group, a 2- (4-thiazolyl) propyl group, a 3- (5-thiazolyl) propyl group, a 3- (2-methyl-4-thiazolyl) propyl group, a 2- (2-methyl-5-thiazolyl) propyl group , a 3- (2,5-dimethyl-4-thiazolyl) propyl group, a 3- (2,4-dimethyl-5-thiazolyl) propyl group, a 3- (2-methyl-5-phenyl-4-) group thiazolyl) propyl, a 3- (2-methyl-4-phenyl-5-thiazolyl) propyl group, a 2- (2-phenyl-4-thiazolyl) propyl group, a 3- (3-phenyl-5-thiazolyl group ) propyl, a 3- (2-phenyl-5-methyl-4-thiazolyl) propyl group, a 4- (2-thiazolyl) butyl group, a 4- (4-thiazolyl) butyl group, a 3- (5) group -thiazolyl) butyl, a 4- (2-methyl-4-thiazolyl) butyl group, a 4- (2-methyl-5-thiazolyl) butyl group, a 4- (2,5-dimethyl-4-thiazolyl group) butyl, a 4- (2,4-dimethyl-5-thiazolyl) butyl group, a 4- (2-methyl-5-phenyl-4-thiazolyl) butyl group, a 4- (2-methyl-4-phenyl) group - 5-thiazolyl) butyl, a group 4- (2-phenyl-4-thiazolyl) butyl, a 4- (4-phenyl-5-thiazolyl) butyl group, a 4- (2-phenyl-5-methyl-4-thiazolyl) butyl group, a 5- (2-thiazolyl) pentyl group, a 5- group (4-thiazolyl) pentyl, a 5- (5-thiazolyl) pentyl group, a 5- (2-methyl-4-thiazolyl) pentyl group, a 5- (2-methyl-5-thiazolyl) pentyl group, a group 5- (2,5-dimethyl-4-thiazolyl) pentyl, a 5- (2,4-dimethyl-5-thiazolyl) pentyl group, a 5- (2-methyl-5-phenyl-4-thiazolyl) pentyl group , a 5- (2-methyl-4-phenyl-5-thiazolyl) pentyl group, a 5- (2-phenyl-4-thiazolyl) pentyl group, a 5- (4-phenyl-5-thiazolyl) pentyl group, a 5- (2-phenyl-5-methyl-4-thiazolyl) pentyl group, a 6- (2-thiazolyl) hexyl group, a 6- (4-thiazolyl) hexyl group, a 6- (5-thiazolyl) group hexyl, a 6- (2-methyl-4-thiazolyl) hexyl group, a 6- (2-methyl-5-thiazolyl) hexyl group, a 6- (2,5-dimethyl-4-thiazolyl) hexyl group, a 6- (2, 4-dimethyl-5-thiazolyl) hexyl group, a 6- (2-methyl-5-phenyl-4-thiazolyl) hexyl group, a 6- (2-methyl-4-phenyl-5-) group thiazolyl) hexyl, a group 6- (2-phenyl-4-) thiazolyl) hexyl, a β- (4-phenyl-5-thiazolyl) hexyl group, a 6- (2-phenyl-5-methyl-4-thiazolyl) hexyl group, a 2- (2,3-dimethylphenyl) - group 4-thiazolylmethyl, a 2- (3-methylphenyl) -5-thiazolylmethyl group, a 2- (3-trifluoromethylphenyl) -5-methyl-4-thiazolylmethyl group, a 2- (3-ethylphenyl) -4-methyl- group 5- thiazolylmethyl, a 2- (2-trifluoroethylphenyl) -4-methyl-5-thiazolylmethyl group, and a 2-methyl-5- (2,4,6-trimethylphenyl) -4-thiazolylmethyl group, provided that in the thiazole ring, 1 or 2 groups selected from the group consisting of a Cl-Cß alkyl group and a phenyl group (wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of of a halogen atom and a Cl-Cß alkyl group substituted or unsubstituted with halogen can be substituted) can be substituted. Examples of the tetrazolyl substituted Cl-Cß alkyl group [wherein, in the tetrazole ring, at least one Cl-Cβ alkyl group can be substituted] can include Cl-Cß alkyl groups substituted with tetrazolyl such as a 5- (1H) group. ) -tetrazolylmethyl, a 2- (5- (lH) -tetrazolyl) ethyl group, a 1- (5- (1H) -tetrazolyl) ethyl group, a 3- (5- (IH) -tetrazolyl) propyl group, a 4- (5- (lH) -tetrazolyl) butyl group, a 5- (5- (IH) -tetrazolyl) pentyl group, a 6- (5- (IH) -tetrazolyl) hexyl group, a 2-methyl- group 3- (5- (1H) -tetrazolyl) propyl, a 1, 1-dimethyl-2- (5- (1H) -tetrazolyl) ethyl group, a 1-methyl-5- (1H) -tetrazolylmethyl group, a group l-ethyl-5- (lH) -tetrazolylmethyl, a 1-n-propyl-5- (lH) -tetrazolylmethyl group, an ln-butyl-5- (lH) -tetrazolylmethyl group, an ln-pentyl-5- group (1H) -tetrazolylmethyl, an ln-hexyl-5- (lH) -tetrazolylmethyl group, a 2- (l-methyl-5- (1H) -tetrazolyl) ethyl group, a 2- (l-ethyl-5-) group (ÍH) - tetrazolyl) ethyl, or n group 2- (ln-propyl-5- (lH) -tetrazolyl) ethyl, a 2- (ln-butyl-5- (lH) -tetrazolyl) ethyl group, a 2- (ln-pentyl-5- ( 1H) -tetrazolyl) ethyl, and a 2- (ln-hexyl-5- (IH) -tetrazolyl) ethyl group, provided that, in the tetrazole ring, a C 1 -C 6 alkyl group can be substituted. Examples of the C 1 -C 6 alkyl group substituted with isoxazolyl [wherein, in the isoxazole ring, at least one C 1 -C 6 alkyl group can be substituted] can include C 1 -C 6 alkyl groups substituted with isoxazolyl such as a group (3-, 4- or 5-isoxazolyl) methyl, a 2- (3-, 4- or 5-isoxazolyl) ethyl group, a l- (3-, 4- or 5-isoxazolyl) ethyl group, a 3- (3-) group , 4- or 5-isoxazolyl) propyl, a 4- (3-, 4- or 5-isoxazolyl) butyl group, a 5- (3-, 4- or 5-isoxazolyl) pentyl group, a group 6- (3 -, 4- or 5-isoxazolyl) hexyl, a 3-methyl-2- (3-, 4- or 5-isoxazolyl) propyl group, a 1, 1-dimethyl-2- (3-, 4- or 5-group) -isoxazolyl) ethyl, a (3-methyl-4-isoxazolyl) methyl group, a (4-ethyl-3-isoxazolyl) methyl group, a (5-n-propyl-3-isoxazolyl) methyl group, a group (4 -n-butyl-5-isoxazolyl) methyl, a (5-n-pentyl-3-isoxazolyl) methyl group, a (3-n-hexyl-4-isoxazolyl) methyl group, a (3,4-dimethyl-5-isoxazolyl) methyl group, a 2- (3-methyl-4-isoxazolyl) ethyl group, an l- (4-ethyl-3-isoxazolyl) ethyl group, a 3- group (5-n-propyl-3-isoxazolyl) propyl, a 4- (4-n-butyl-5-isoxazolyl) butyl group, a 5- (5-n-pentyl-3-isoxazolyl) pentyl group, a group 6 - (3-n-hexyl-4- isoxazolyl) hexyl, and a 2- (3,4-dimethyl-5-isoxazolyl) ethyl group, provided that, in the isoxazole ring, 1 or 2 C1-C6 alkyl groups they can be replaced. Examples of the C1-C6 alkyl group substituted with 1,2,4-oxadiazolyl [wherein, in the 1,2,4-oxadiazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, a C 1 -C 6 alkyl group can be substituted)) can include C 1 -C 6 alkyl groups substituted with 1,2,4-oxadiazolyl such as a (3- or 5-) 1,2-oxadiazolylmethyl group, a 2 - (group 3- 5) l, 2,4-oxadiazolyl) ethyl, a group l - ((3- 5) l, 2,4-oxadiazolyl) ethyl, a group 3 - ((3- 5) l, 2 , 4-oxadiazolyl) propyl, a 4 - ((3- or 5-) l, 2,4-oxadiazolyl) butyl group, a 5 - ((3- or 5-) l, 2,4-oxadiazolyl) pentyl group , a group 6 - ((3- or 5-) l, 2,4-oxadiazolyl) -yl, a 3-methyl-2- ((3 -5) l, 2,4-oxadiazolyl) propyl group, a group 1 , l-dimethyl-2- ((3- or 5-) 1,2,4-oxadiazolyl) ethyl, a group (3-phenyl-5-l, 2,4-oxadiazolyl) methyl, a group (5-phenyl) -3-1, 2,4-oxadiazolyl) methyl, a group (3- (3-methylphenyl) -5-1,2,4-oxadiazolyl) methyl, a group (5- (3,4-dimethylphenyl) -3 -1, 2, 4-oxadiazolyl) methyl, a gru po (3- (2,4,6-trimethylphenyl) -5-1,2,4-oxadiazolyl) methyl, a group (5- (2-ethylphenyl) -3-1,2, 4- oxadiazolyl) methyl, a 2- ((3-n-propylphenyl) -5-1,2-4-oxadiazolyl) ethyl group, a 1- (5- (4-n-butylphenyl) -3-1,2-4-oxadiazolyl) ethyl group , a 3- (3- (3-n-pentylphenyl) -5-1,2-4-oxadiazolyl) propyl group, a 4- (5- (5-n-hexylphenyl) -3-1, 2, 4 group oxadiazolyl) butyl, a 5- (3- (3-ethyl-4-methylphenyl) -5- 1, 2,4-oxadiazolyl) pentyl group, and a 6- (5- (2-methylphenyl) -3- group) 1,2,4-oxadiazolyl) hexyl, provided that, in the 1,2,4-oxadiazole ring, a phenyl group can be substituted, provided that (wherein, in the phenyl ring, 1 to 3 groups C1-C6 alkyl can be substituted). Examples of C1-C6 alkyl group substituted with benzofurazanyl may include 4-benzofurazanilmetilo, 5-benzofurazanilmetilo, 6-benzofurazanilmetilo, 7-benzofurazanilmetilo, 1- (4-benzofurazanyl) ethyl, 2- (5-benzofurazanyl) ethyl, 3- ( 6-benzofurazanyl) propyl, 4- (7-benzofurazanyl) butyl, 5- (4-benzofurazanyl) pentyl, 6- (5-benzofurazanyl) hexyl, 2-methyl-3- (6-benzofurazanyl) propyl, and 1, l -dimethyl-2- (7-benzofurazanyl) ethyl. The phenylamino group [wherein a C1-C6 can be substituted in the N position phenylamino group, and wherein, on the phenyl ring phenylamino group, at least a C1-C6 unsubstituted or substituted by halogen may to be substituted] can be an unsubstituted phenylamino group (alias: anilino group), or a phenylamino group in which the substituted or unsubstituted C1-C6 alkoxy groups with halogen 1 to 3 defined above are substituted. Examples of the phenylamino group may include a phenylamino group, a 2-methoxyphenylamino methoxyphenylamino 3-methoxyphenylamino 4-ethoxyphenylamino 3-group, a group, a group, a 2- ethoxyphenylamino a group, 4- ethoxyphenylamino group, a 4 -n-propoxyphenylamino, a 4-tert-butoxyphenylamino group, a group. 4-n-butoxifenilamino a-trifluoromethoxy 2 trifluoromethoxy 3--trifluoromethoxy 4-pentafluoroetoxifenilamino 2-dimethoxyphenylamino 3 group, a group, a group, a group, a 3-pentafluoroetoxifenilamino group, a 2, a 3, 4, 5-trimetoxifenilamino a group N-phenyl-N-methylamino 5-ditrifluorometoxifenilamino group 4-n-pentiloxifenilamino group, a 4-n-hexiloxifenilamino, a group 3, an N- (2-methoxyphenyl) -N- ethylamino, an N- (3-methoxyphenyl) -Nn-propylamino group, a N- (4-methoxyphenyl) -N-butylamino group, a N- (2-ethoxyphenyl) -Nn-pentylamino group, an N- (3-ethoxyphenyl) -N-hexylamino group, a N- (4-ethoxyphenyl) -N-methylamino group, a N- (4-n-propoxyphenyl) -N-ethylamino group, a N- group ( 4-tert-butoxyphenyl) -N-propylamino, an N- (4-n-butoxyphenyl) -N-butylamino group, an N- (2-trifluoromethoxyphenyl) -N-pentylamino group, a N- (3-trifluoromethoxyphenyl) group -N-hexylamino, an N- (4-trifluoromethoxyphenyl) -N-methylamino group, a N- (2-pentafluoroethoxyphenyl) -N-ethylamino group, a N- (3-pentafluoroethoxyphenyl) -N-propylamino group, a N group - (2,3-dimethoxyphenyl) -N-methylamino, an N- (3,4,5-trimethoxyphenyl) -N-methylamino group, an N- (4-n-pentyloxyphenyl) -N-methylamino group, a N group - (4-n-hexyloxyphenyl) -N-methylamino, and a N- (3,5-ditrifluoromethoxyphenyl) -N-methylamino group. Examples of the phenoxy group (wherein, in the phenyl ring, a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen can be substituted) can include phenoxy groups such as a phenoxy group, a 2-methoxyphenoxy group, a 3- group methoxyphenoxy, a 4-methoxyphenoxy group, a 4-isopropoxyphenoxy group, a 4-n-butoxyphenoxy group, a 2,4-dimethoxyphenoxy group, a 2,3-dimethoxyphenoxy group, a 2, 3, 4, 5, 6 group pentamethoxyphenoxy, a 3, 5-dimethoxyphenoxy group, a 2,5-dimethoxyphenoxy group, a 2, 4,6-trimethoxyphenoxy group, a 3, 5-di (trifluoromethoxy) phenoxy group, a 4-methoxy-3-trifluoromethoxyphenoxy group, a 2,6-dimethoxyphenoxy group, a 2-trifluoromethoxyphenoxy group, a 3-trifluoromethoxyphenoxy group, a 4-trifluoromethoxyphenoxy group, a 2,3-di (trifluoromethoxy) phenoxy group, a 2,4-di (trifluoromethoxy) phenoxy group, a 2-pentafluoroethoxyphenoxy group, a 3-pentafluoroethoxyphenoxy group, a 4-pentafluoroethoxyphenoxy group, a 2-isopropoxyphenoxy group, a 3-isopropoxyphenoxy group, a rupo 4-isopropoxyphenoxy, a 2- tert-butoxyphenoxy group, a 3-tert-butoxyphenoxy group, a 4-tert-butoxyphenoxy group, a 2-sec-butoxyphenoxy group, a 3- sec-butoxyphenoxy group, a 4-sec group -butoxifenoxi, a 4-n-hexyloxyphenoxy group, a 2-n-heptafluoropropoxyphenoxy group, a 3-n-heptafluoropropoxyphenoxy group, and a 4-n-heptafluoropropoxyphenoxy group, provided that, on the phenyl ring, 1 to 5 groups , and preferably 1 to 3 groups selected from the group consisting of C1-C6 alkoxy groups substituted or unsubstituted with halogen can be substituted. Examples of the amino group (wherein, in the amino group, at least one selected from the group consisting of a C1-C6 alkyl group and a phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted as a substituent) can include amino groups such as a amino group, a methylamino group, a dimethylamino group, an ethylamino group, a diethylamino group, an n-propylamino group, an n-butylamino group, an n-pentylamino group, a 3-n-hexylamino group, a phenylamino group, an (4-chlorophenyl) amino group, a (4-bromophenyl) amino group, a (2,4-dichlorophenyl) amino group, a (2,4,6-trichlorophenyl) amino group, a group (2,3,4, 5,6-pentafluorophenyl) amino, a (4-fluorophenyl) amino group, a (4-iodophenyl) amino group, a (4-chlorophenyl) amino group, a group or (3-methylphenyl) amino, a (4-trifluoromethylphenyl) amino group, a (4-trifluoromethylphenyl) amino group, a 3- (4-trifluoromethylphenyl) amino group, a (3,4-dimethylphenyl) amino group, a group (3, 4, 5-trimethylphenyl) amino, a (2-methoxyphenyl) amino group, a (4-trifluoromethoxyphenyl) amino group, a 3- (4-trifluoromethoxyphenyl) amino group, a (3,5-dimethoxyphenyl) amino group , a (2,5-dimethoxyphenyl) amino group, a (2,4,6-trimethoxyphenyl) amino group, an N-methyl-N- (4-trifluoromethylphenyl) amino group, and an N-ethyl-N- group ( 4-trifluoromethoxyphenyl) amino, provided that, in the amino group, 1 6 2 groups selected from the group consisting of a C1-C6 alkyl group and a phenyl group [wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted C1-C6 alkoxy group or not substituted with halogen can be substituted] can be substituted as substituents. Examples of the piperidyl group [wherein, in the piperidine ring, at least one selected from the group consisting of a phenoxy group (wherein, in the phenyl ring, a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen can be substituted as a substituent) and an amino group (wherein, at the amino group, at least one selected from the group consisting of a Cl-Cß alkyl group and a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted as a substituent) can be substituted] , may include piperidyl groups such as a 2-piperidyl group, a 3-piperidyl group, a 4-piperidyl group, a 2,4-diamino-1-piperidyl group, a 2, 6-triamino-1-piperidyl group, a 4-amino-3-phenoxy-1-piperidyl group, a 4-faith group noxy-2-amino-1-piperidyl, a 2-amino-1-piperidyl group, a 3-amino-1-piperidyl group, a 4-amino-1-piperidyl group, a 4-methylamino-1-piperidyl group, a 4-ethylamino-1-piperidyl group, a 4-n-propylamino-1-piperidyl group, a 4-dimethylamino-1-piperidyl group, a 4-diethylamino-1-piperidyl group, a 4-di-n-group propylamino-1-piperidyl, a 4-phenylamino-1-piperidyl group, a 4- (N-phenyl-N-methylamino) -1-piperidyl group, a 4- (2-flurophenylamino) -1-piperidyl group, a group 4- (3-flurophenylamino) -1-piperidyl, a 4- (4-flurophenylamino) -1-piperidyl group, a 4- (2-chlorophenylamino) -1-piperidyl group, a 4- (2,3-chlorophenylamino group ) -1-piperidyl, a 4- (4-chlorophenylamino) -1-? Iperidyl group, a 4- (2, 3-dichlorophenylamino) -1-piperidyl group, a 4- (2,4,6-trifluorophenylamino) group -1-piperidyl, a 4- (2,4-dichlorophenylamino) -1-piperidyl group, a 4- (3,4-dichlorophenylamino) -1-piperidyl group, a 4- (3,5-dichlorophenylamino) -1 group -piperidyl, a group 4- (2 , 3, 4, 5, 6-pentafluorophenylamino) -1-piperidyl, a 4- (2-trifluoromethylphenylamino) -1-piperidyl group, a 4- (2-methylphenylamino) -1-piperidyl group, a 4- (2-group , 3-dimethylphenylamino) -1-piperidyl, a 4- (2-trifluoromethylphenylamino) -1-piperidyl group, a 4- (2,4,6-trimethylphenylamino) -1-piperidyl group, a 4- (4-trifluoromethylphenylamino group ) -1-piperidyl, an 4- (2-pentafluoroethylphenylamino) -1-piperidyl group, a 4- (3-pentafluoroethylphenylamino) -1-piperidyl group, a 4- (4-pentafluoroethylphenylamino) -1-piperidyl group, a group 4- (2-trifluoromethoxyphenylamino) -1-piperidyl, a 4- (2-methoxyphenylamino) -1-piperidyl group, a 4- (2,3-dimethoxyphenylamino) -1-piperidyl group, a 4- (2, 4) group , 6-trimethoxyphenylamino) -1-piperidyl, a 4- (N-methyl-N- (2,4,6-trimethoxyphenylamino)) -1-piperidyl group, a 4- (N-methyl-N- (3, 4-dimethylphenylamino)) -1-piperidyl, a 4- (3-trifluoromethoxyphenylamino) -1-piperidyl group, a 4- (4-trifluoromethoxyphenylamino) -1-piperidyl group, a 4- (2-pentafluoroethoxyphenylamino) -1-piperidyl group, a 4- (3-pentafluoroethoxyphenylamino) -1-piperidyl group, a 4- (4-pentafluoroethoxyphenylamino) -1-piperidyl group, a 4- (2-fluorophenylamino group ) -1-piperidyl, a 4- (3-fluorophenylamino) -1-piperidyl group, a 4- (4-fluorophenylamino) -1-piperidyl group, a 4-phenoxy-1-piperidyl group, a group 2, 4- diphenoxy-1-piperidyl, a 2,4,6-triphenoxy-1-piperidyl group, a 4- (2-methoxyphenoxy) -1-piperidyl group, a 1- (3-methoxyphenoxy) -4-piperidyl group, a group 1- (4-methoxyphenoxy) -4-piperidyl, a 2- (2-ethoxyphenoxy) -3-piperidyl group, a 3- (3-ethoxyphenoxy) -4-piperidyl group, a 4- (4-ethoxyphenoxy) group - 5-piperidyl, a 3- (4-n-propoxyphenoxy) -2-piperidyl group, a 2- (4-tert-butoxyphenoxy) -1-piperidyl group, a 1- (4-n-butoxyphenoxy) -2-piperidyl group, a 2- (2-trifluoromethoxyphenoxy) -3-piperidyl group, a 3- (3-trifluoromethoxyphenoxy) -4-piperidyl group, a 4- (4-trifluoromethoxyphenoxy) -3-piperidyl group, a 3- (2-pentafluoroethoxyphenoxy) group -2-piperidyl, a 6- (3-pentafluoroethoxyphenoxy) -1-piperidyl group, a l- (2,3-dimethoxyphenoxy) -4-piperidyl group, a 4- (3,4,5-trimethoxyphenoxy) -1 group -piperidyl, a 4- (4-n-pentyloxyphenoxy) group, and a 4- (4-n-hexyloxyphenoxy) -1-piperidyl group, provided that, in the piperidine ring, 1 to 3 groups selected from the group consists of a phenoxy group (wherein, in the phenyl ring, 1 to 5, and preferably 1 to 3 C 1 -C 6 alkoxy groups substituted or unsubstituted with halogen can be substituted as substituents) and an amino group (wherein, in the amino group, 1 or 2 groups selected from the group consisting of an alkaline group uilo C1-C6 and a phenyl group [wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] can be substituted as substituents) can be substituted. Examples of the piperazinyl group [wherein, in the piperazine ring, at least one selected from the following groups can be substituted: a C1-C6 alkoxycarbonyl group, a C1-C6 alkyl phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted), a C2- alkenyl group C6 phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted), and a benzoyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and an alkoxy group Cl-Cß su substituted or unsubstituted with halogen can be substituted)), can include piperazinyl groups such as a (1-, 2- or 3-) piperazinyl group, a 4-tert-butoxycarbonyl-1-piperazinyl group, a 4-ethoxycarbonyl group 1-piperazinyl, a 4-methoxycarbonyl-1-piperazinyl group, a 2,4-dimethoxycarbonyl-1-piperazinyl group, a 2,4,6-triethoxycarbonyl-1-piperazinyl group, a 4- (4-trifluoromethoxybenzyl) - group 1-piperazinyl, a 4- (4-chlorobenzyl) -1-piperazinyl group, a 4- (4-methoxybenzyl) -1-piperazinyl group, a 4- (4-bromobenzyl) -1-piperazinyl group, a 4- group (4-methylbenzyl) -1-piperazinyl, a 4- (2,4-dichlorobenzyl) -1-piperazinyl group, a 4- (3,4-dimethoxybenzyl) -1-piperazinyl group, a 4- (2, 4) group , 6-trifluorobenzyl) -1-piperazinyl, a 4- (3,4-dimethylbenzyl) -1-piperazinyl group, a 4- (2,4,6-trimethoxybenzyl) -1-piperazinyl group, a 4- (2-group , 4,6-trimethylbenzyl) -1-piperazinyl, a 4- (4-iodobenzyl) -1-piperazinyl group, a 4- (4-trifluoromethyl) group benzyl) -1-piperazinyl, a 4- (3,4-dichlorobenzyl) -1-piperazinyl group, a 4- (3- (4-trifluoromethylphenyl) -2-propenyl) -1-piperazinyl group, a 4- ( 3- (4-trifluoromethylphenyl) -2-propenyl) -1-piperazinyl, a 4- (4-trifluoromethylbenzoyl) -1-piperazinyl group, a 4- (3- (4-chlorophenyl) -2-propenyl) -1 group -piperazinyl, a 4- (3- (4-methylphenyl) -2-propenyl) -1-piperazinyl group, a 4- (3- (4-methoxyphenyl) -2-propenyl) -1-piperazinyl group, a group 4 - (3- (3,4-dimethylphenyl) -2-propenyl) -1-piperazinyl, a 4- (3- (3,4-dimethoxyphenyl) -2-propenyl) -1-piperazinyl group, a group 4- ( 3- (3, 4,5-trimethylphenyl) -2-propenyl) -1-piperazinyl, a 4- (3- (3, 4, 5-trimethoxyphenyl) -2-propenyl) -1-piperazinyl group, a 4- (3- (3,4-dichlorophenyl) -2-propenyl) -1-piperazinyl group , a 4- (3- (2,4,6-trifluorophenyl) -2-propenyl) -1-piperazinyl group, a 4- (3- (4-iodophenyl) -2-propenyl) -1-piperazinyl group, a 4- (3- (3-Bromophenyl) -2-propenyl) -1-piperazinyl group, a 4- (4-fluorobenzyl) -1-piperazinyl group, a 4- (4-methylbenzoyl) -1-piperazinyl group, a 4- (4-methoxybenzoyl) -1-piperazinyl group, a 4- (3,4-dimethylbenzoyl-l-piperazinyl group, a 4- (2,4-dimethylbenzoyl-l-piperazinyl group, a 4- (3 group, 4, 5-trimethylbenzoyl-l-piperazinyl, a 4- (2,4,6-trimethoxybenzoyl-1-piperazinyl group, a 4- (4-chlorobenzoyl) -1-piperazinyl group, a 4- (2, 4, 6-trifluorobenzoyl) -1-piperazinyl, a 4- (4-bromobenzoyl) -1-piperazinyl group, a 4- (4-iodobenzoyl) -1-piperazinyl group, a 4- (3,4-dichlorobenzoyl) -1 group -piperazinyl, a 4- (4-fluorobenzoyl) -1-piperazinyl group, a 4-benzyl-3- (3-phenyl-2-prop) group enyl) -1-piperazinyl, and a 4-benzoyl-3, 5-dibenzyl-1-piperazinyl group, provided that, in the piperazine ring, 1 to 3 groups selected from the following groups can be substituted: the group C 1 -C 6 alkoxycarbonyl described above, the C 1 -C 6 alkyl phenyl group described above (wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), the C2-C6 alkenyl group phenyl described above (which is unsubstituted, or which is composed of 1 or 2 phenyl groups, wherein 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can to be substituted, and alkenyl groups containing 2 to 6 carbon atoms and having 1 to 3 double bonds), and the benzoyl group described above (wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted). Examples of the homopiperazinyl group [wherein, in the homopiperazine ring, at least one selected from the group consisting of a C1-C6 alkoxycarbonyl group and a C1-C6 alkyl phenyl group (wherein, in the phenyl ring, at least one selected of the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] can include homopiperazinyl groups such as a group (1-, 2-, 3-, 4-, 5-, 6- or 7-) homopiperazinyl, a 3, 4-dibenzyl-l-homopiperazinyl group, a 2,7-dibenzyl-1-homopiperazinyl group, a 2, 3, 4-tribencyl-l-homopiperazinyl group, a 2, 4,6-tribenyl-l-homopiperazinyl group, a 4-benzyl-l-homopiperazinyl group, a 4- (2-phenethyl) -l- group homopiperazinyl, a 4- (3-phenylpropyl) -1-homopiperazinyl group, a 4- (4-phenylbutyl) -1-homopiperazinyl group, a 4- (5-phenylpentyl) -1-homopiperazinyl group , a 4- (6-phenylhexyl) -1-homopiperazinyl group, a 4- (2-fluorobenzyl) -1-homopiperazinyl group, a 4- (3-fluorobenzyl) -1-homopiperazinyl group, a 4- (4-) group fluorobenzyl) -1-homopiperazinyl, a 4- (2-chlorobenzyl) -1-homopiperazinyl group, a 4- (3-chlorobenzyl) -1-homopiperazinyl group, a 4- (4-chlorobenzyl) -1-homopiperazinyl group, a 4- (2, 3-dichlorobenzyl) -1-homopiperazinyl group, a 4- (2,4-dichlorobenzyl) -1-homopiperazinyl group, a 4- (3,4-dichlorobenzyl) -1-homopiperazinyl group, a group 4 - (3,5-dichlorobenzyl) -1-homopiperazinyl, n group 4 4-- (3, 4, 5-trichlorobenzyl) -1- homopiperazinyl, a group 4- (2, 3, 4, 5, 6-pentafluorobenzyl -1- homopiperazinyl, a 4- (2-trifluoromethylbenzyl group -1-homopiperazinyl, a 4- (3-trifluoromethylbenzyl-1-homopiperazinyl group, a 4- (4-trifluoromethylbenzyl-1-homopiperazinyl group, a 4- (4-methylbenzyl-1-homopiperazinyl, a 4- (3-group , -dimethylbenzyl-1-homopiperazinyl, a 4- (2,4,6-trimethylbenzyl-1-homopiperazinyl group, a 4- (2-pentafluoroethylbenzyl-1-homopiperazinyl, a 4- (3-pentafluoroethylbenzyl-1-homopiperazinyl) group , a 4- (4-pentafluoroethylbenzyl-1-homopiperazinyl group, a 4- (2-trifluoromethoxybenzyl] -1-homopiperazinyl group, a 4- (3-trifluoromethoxybenzyl] -1-homopiperazinyl group, a 4- (4-trifluoromethoxybenzyl) group; -1-homopiperazinyl, a 4- (4-methoxybenzyl] -1-homopiperazinyl group, a 4- (3,4-dimethoxybenzyl) -1-homopiperazinyl group, a 4- (2,4,6-trimethoxybenzyl) group; -homopiperazinyl, a 4- (2-pentafluoroethoxybenzyl) -1-homopiperazinyl group, a 4- (3-pentafluoroethoxybenzyl) -1-homopiperazinyl group, a 4- (4-pentafluoroethoxybenzyl) -1-homopiperazinyl group, a 4- ( 2- (4-trifluoromethoxyphenyl) ethyl) -1-homopiperazinyl, a 4- (3- (4-trifluoromethoxyphenyl) propyl) -1-homopiperazinyl group, a 4- (4- (4-trifluoromethoxyphenyl) butyl) -1- group homopiperazinyl, a 4- (5- (4-trifluoromethoxyphenyl) pentyl) -1-homopiperazinyl group, a 4- (6- (4-trifluoromethoxyphenyl) hexyl) -1- homopiperazinyl group, a 4- (2- (4- trifluoromethylphenyl) ethyl) -1-homopiperazinyl, a 4- (3- (4-trifluoromethylphenyl) propyl) -1-homopiperazinyl group, a 4- (4- (4-trifluoromethylphenyl) butyl) -1-homopiperazinyl group, a group 4 - (5- (4-trifluoromethylphenyl) pentyl) -1-homopiperazinyl, a group 4- (6- (4-trifluoromethylphenyl) hexyl) -1-homopiperazinyl, a 4-tert-butoxycarbonyl- (1-, 2-, 3-, 5-, 6- or 7-) homopiperazinyl group, a 4-methoxycarbonyl group ( 1-, 2-, 3-, 5-, 6- or 7-) homopiperazinyl, and a 4-ethoxycarbonylcarbonyl (1-, 2-, 3-, 5-, 6- or 7-) homopiperazinyl group, provided that, in the homopiperazine ring, 1 to 3 groups selected from the group consisting of the C1-C6 alkoxycarbonyl group described above and a C1-C6 alkyl phenyl group (wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted. Examples of the phenyl group substituted with phenoxy (wherein, in the phenyl ring, at least one Cl-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can include phenyl groups substituted with phenoxy such as a 2-phenoxyphenyl group, a 2,3-difenoxifenyl group, a 2, 4,6-trifenoxifenyl group, a 3- (2-methoxyphenoxy) phenyl group, a 4- (3-methoxyphenoxy) phenyl group, a 2- ( 4-methoxyphenoxy) phenyl, a 3- (4-isopropoxy-enoxy) phenyl group, a 4- (4-n-butoxy-enoxy) phenyl group, a 2- (2,4-dimethoxy-enoxy) phenyl group, a 3-group - (2, 3-dimethoxy-enoxi) phenyl, a group 4- (2,3,4,5,6-pentamethoxyphenoxy) phenyl, a 2- (3,5-dimethoxy-enoxy) phenyl group, a 3- (2,5-dimethoxy-enoxy) phenyl group, a group 4 - . 4 - (2, 4, 6-t rimet oxy phenoxy) phenyl, a 2 - (3,5-di (trifluoromethoxy) phenoxy) phenyl group, a 3- (4-methoxy-3-trifluoromethoxyphenoxy) phenyl group, a 4- (2,6-dimethoxy-enoxi) phenyl group, a 2- (2-trif luoromethoxy-enoxy) phenyl group, a 3- (3-t rif loromethoxy-enoxi) phenyl group, a 4- (4-trif luoromethoxy-enoxi) group ) phenyl, a 2- (2,3-di (trifluoromethoxy) phenoxy) phenyl group, a 3- (2,4-di (trifluoromethoxy) phenoxy) phenyl group, a 4- (2-pentafluoroethoxyphenoxy) phenyl group, a 2- (3-pentaf luoroethoxy-enoxi) phenyl group, a 3- (4-pentafluoroethoxyphenoxy) phenyl group, a 4- (2-isopropoxy-enoxy) phenyl group, im 2- (3-isopropoxy-enoxy) phenyl group, im 3-group - (4-isopropoxy-enoxi) phenyl, a 4- (2-tert-butoxy-enoxi) phenyl group, a 2- (3-tert-butoxy-enoxi) phenyl group, a 3- (4-tert-butoxy-phenoxy) -phenyl group , a 4- (2-sec-butoxifenoxi) phenyl group, a 3- (3-sec-butoxifenoxi) phenyl group, a 4- (4-sec-butoxifenoxi) phenyl group, a 2- (4-) group n-hexyl oxyphenoxy) phenyl, a 3- (2-n-heptafluoropropoxyphenoxy) phenyl group, a 4- (3-n-heptafluoropropoxyphenoxy) phenyl group, and a 2- (4-n-heptafluoropropoxyphenoxy) phenyl group, provided that, in the phenyl ring, 1 to 5, and preferably 1 to 3 C 1 -C 6 alkoxy groups substituted or unsubstituted with halogen can be substituted. Examples of the phenoxy group [wherein, on the phenyl ring, at least one selected from the group consisting of a C1-C6 alkoxy group substituted or unsubstituted by halogen and a phenyl group substituted by phenoxy (wherein, on the phenyl ring , at least one C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] can include phenoxy groups such as a phenoxy group, a 2-methoxyphenoxy group, a 3-methoxyphenoxy group, a 4-methoxyphenoxy group , a 4-isopropoxyphenoxy group, a 4-n-butoxyphenoxy group, a 2,4-dimethoxyphenoxy group, a 2,3-dimethoxyphenoxy group, a 2, 3, 4, 5, 6-pentamethoxyphenoxy group, a 3, 5 group -methoxyphenoxy, a 2, 5-dimethoxyphenoxy group, a 2, 4,6-trimethoxyphenoxy group, a 3, 5-di (trifluoromethoxy) phenoxy group, a 4-methoxy-3-trifluoromethoxyphenoxy group, a 2,6-dimethoxyphenoxy group , a 2-trifluoromethoxyphenoxy group, a 3-trifluoromethoxyphenoxy group, a 4-trifluoromethoxyphenoxy group, a 2,3-di (trifluoromethazine group oxy) phenoxy, a 2,4-di (trifluoromethoxy) phenoxy group, a 2-pentafluoroethoxyphenoxy group, a 3-pentafluoroethoxyphenoxy group, a 4-pentafluoroethoxyphenoxy group, a 2-isopropoxyphenoxy group, a 3-isopropoxyphenoxy group, a 4- group isopropoxyphenoxy, a 2- tert-butoxyfenoxy group, a 3-tert-butoxyphenoxy group, a 4- tert-butoxyphenoxy group, a 2-sec-butoxyphenoxy group, a 3- sec-butoxyphenoxy group, a 4-sec-butoxyphenoxy group, a 4-n-hexyloxyphenoxy group, a 2-n-heptafluoropropoxyphenoxy group, a 3-n-heptafluoropropoxyphenoxy group, a 4-n-heptafluoropropoxyphenoxy group, a 2- (2-phenoxyphenyl) phenoxy group, a 2, 3-di group (2-phenoxyphenyl) phenoxy, a 2,3-di (2-phenoxyphenyl) -4-methoxyphenoxy group, a 2,4-dimethoxy-3- (3-phenoxyphenyl) phenoxy group, a 3- (2, 3-) group diphenoxyphenyl) phenoxy, a 4- (2,4-b-triphenoxyphenyl) phenoxy group, a 2- (3- (2-methoxyphenoxy) phenyl) phenoxy group, a 3- (4- (3-methoxyphenoxy) phenyl) phenoxy group , a group 4- (2- (4-methoxyphenoxy) phenyl) phenoxy, a group 2- (3- (4-isop) opoxyphenoxy) phenyl) phenoxy, a 3- (4- (4-n-butoxyphenoxy) phenyl) phenoxy group, a 4- (2- (2,4-dimethoxyphenoxy) phenyl) phenoxy group, a 2- (3- ( 2,3-dimethoxyphenoxy) phenyl) phenoxy, a 3- (4- (2, 3, 4, 5, 6-pentamethoxyphenoxy) phenyl) phenoxy group, a 4- (2- (3,5-dimethoxyphenoxy) phenyl group) phenoxy, a 2- (3- (2,5-dimethoxyphenoxy) phenyl) phenoxy group, a 3- (4- (2,4,6-trimethoxyphenoxy) phenyl) phenoxy group, a 4- (2- (3, 5- di (trifluoromethoxy) phenoxy) phenyl) phenoxy, a 2- (3- (4-methoxy-3-trifluoromethoxyphenoxy) phenyl) phenoxy group, a 3- (4- (2,6-dimethoxyphenoxy) phenyl) phenoxy group, a 4- (2- (2-trifluoromethoxyphenoxy) phenyl) phenoxy group, a 2- (3- (3-trifluoromethoxyphenoxy) phenyl) phenoxy group , a group 3- (4- (4-trifluoromethoxyphenoxy) phenyl) phenoxy, a group 4- (2- (2,3-di (trifluoromethoxy) phenoxy) phenyl) phenoxy, a group 2- (3- (2,4 -di (trifluoromethoxy) phenoxy) phenyl) phenoxy, a 3- (4- (2-pentafluoroethoxyphenoxy) phenyl) phenoxy group, a 4- (2- (3-pentafluoroethoxyphenoxy) phenyl) phenoxy group, a 2- (3-) group (4-pentafluoroethoxyphenoxy) phenyl) phenoxy, a 3- (4- (2-isopropoxyphenoxy) phenyl) phenoxy group, a 4- (2- (3-isopropoxyphenoxy) phenyl) phenoxy group, a 2- (3- (4 -isopropoxyphenoxy) phenyl) phenoxy, a 3- (2- (2-tert-butoxyphenoxy) phenyl) phenoxy group, a 4- (2- (3-tert-butoxyphenoxy) phenyl) phenoxy group, a 2- (3-) group (4-tert-butoxyphenoxy) phenyl) phenoxy, a 3- (4- (2-sec-butoxyphenoxy) phenyl) phenoxy group, a 2- (2- (3-sec-butoxyphenoxy) phenyl) phenoxy group, a group 2 - (3- (4-sec-butoxyphenoxy) phenyl) phenoxy, a group 4- (2- (4-n- hexyloxyphenoxy) phenyl) phenoxy, a 2- (3- (2-n-heptafluoropropoxyphenoxy) phenyl) phenoxy group, a 3- (4- (3-n-heptafluoropropoxyphenoxy) phenyl) phenoxy group, and a 4- (2-) group (4-n-heptafluoropropoxyphenoxy) phenyl) phenoxy, provided that, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a Cl-Cβ alkoxy group substituted or unsubstituted with halogen and a phenyl group substituted with phenoxy (wherein, in the phenyl ring, 1 to 5, and preferably 1 to 3 Cl-Cβ alkoxy groups substituted or unsubstituted with halogen can be substituted) can be substituted. Examples of the homopiperazinyl group (wherein, in the homopiperazine ring, at least one selected from the following groups can be substituted: a C1-Cβ alkoxycarbonyl group, a C1-C3 alkyl phenyl group [wherein, in the phenyl ring, less one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], a phenyl group [wherein , in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] , a Cl-Cβ phenyl alkoxycarbonyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted by halogen, and a group at Cl-Cβ coxy substituted or unsubstituted by halogen can be substituted], a phenylcarbamoyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or not substituted with halogen, and a C1-Cß alkoxy group substituted or unsubstituted with halogen can be substituted], a C2-C6 alkenyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of one atom of halogen, a Cl-Cβ alkyl group substituted or not substituted by halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted by halogen can be substituted], and a benzoyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted]), can include homopiperated groups zinyl such as a group (1-, 2-, 3-, 4-, 5-, 6- or 7-) homopiperazinyl, a 4-tert-butoxycarbonyl-1-homopiperazinyl group, a 4-ethoxycarbonyl-1-homopiperazinyl group , a 4-methoxycarbonyl-l-homopiperazinyl group, a 2,4-dimethoxycarbonyl-l-homopiperazinyl group, a 2,4,6-triethoxycarbonyl-l-homopiperazinyl group, a 4- (4-trifluoromethoxybenzyl) -1-homopiperazinyl group , a 4- (4-chlorobenzyl) -1-homopiperazinyl group, a 4- (4-methoxybenzyl) -1-homopiperazinyl group, a 4- (4-bromobenzyl) -1-homopiperazinyl group, a 4- (4-methylbenzyl) -1- homopiperazinyl group, a 4- (2 group, 4-dichlorobenzyl) -1- homopiperazinyl, a 4- (3,4-dimethoxybenzyl) -1- homopiperazinyl group, a 4- (2,4,6-trifluorobenzyl) -1-homopiperazinyl group, a 4- (3 group, 4-dimethylbenzyl) -1-homopiperazinyl, a 4- (2,4,6-trimethoxybenzyl) -1-homopiperazinyl group, a 4- (2,4,6-trimethylbenzyl) -1-homopiperazinyl group, a 4- ( 4-iodobenzyl) -1-homopiperazinyl, a 4- (4-trifluoromethylbenzyl) -1-homopiperazinyl group, a 4- (3,4-dichlorobenzyl) -1-homopiperazinyl group, a 4- (3- (4-trifluoromethylphenyl) group ) -2-propenyl) -1-homopiperazinyl, a 4- (3- (4-trifluoromethylphenyl) -2-propenyl) -1-homopiperazinyl group, a 4- (4-trifluoromethylbenzoyl) -1-homopiperazinyl group, a group 4 - (3- (4-chlorophenyl) -2-propenyl) -1-homopiperazinyl, a 4- (3- (4-methylphenyl) -2-propenyl) -1-homopiperazinyl group, a 4- group (3- (4-methoxyphenyl) -2-propenyl) -1-homopiperazinyl, a group 4- (3- (3, 4-dimethylphenyl) -2-propenyl) -1-homopiperazinyl, a 4- (3- (3,4-dimethyloxyphenyl) -2-propenyl) -1-homopiperazinyl group, a 4- group (3- (3, 4, 5-trimethylphenyl) -2-propenyl) -1-homopiperazinyl, a 4- (3- (3,4,5-trimethoxyphenyl) -2-propenyl) -1-homopiperazinyl group, a group 4- (3- (3,4-dichlorophenyl) -2-propenyl) -1-homopiperazinyl, a 4- (3- (2,4,6-trifluorophenyl) -2-propenyl) -1-homopiperazinyl group, a group 4- (3- (4-iodophenyl) -2-propenyl) -1-homopiperazinyl, a 4- (3- (3-bromophenyl) -2-propenyl) -1- homopiperazinyl group, a 4- (4-fluorobenzyl group -1-homopiperazinyl, a 4- (4-methylbenzoyl-1-homopiperazinyl, a 4- (4-methoxybenzoyl-1-homopiperazinyl, a 4- (3,4-dimethylbenzoyl-1-homopiperazinyl, a 4- group (2,4-dimethoxybenzoyl-1-homopiperazinyl, a 4- (3,4-trimethylbenzoyl-1-homopiperazinyl) group, a 4- (2,4-, 6-trimethoxybenzoyl-1-homopiperazinyl group, a 4- ( 4-chlorobenzoyl-1-homopiperazinyl, a group 4- (2, 4, 6-tr ifluorobenzoyl-1-homopiperazinyl, a 4- (4-bromobenzoyl-1-homopiperazinyl, a 4- (4-iodobenzoyl-1-homopiperazinyl, a 4- (3,4-dichlorobenzoyl-1-homopiperazinyl, a group 4 - (4-fluorobenzoyl-1-homopiperazinyl, a 4-benzyl-3- (3-phenyl-2-propenyl-1-homopiperazinyl, a 4-benzoyl-3, 5-dibenzyl-l homopiperazinyl group, a group 2, 7-dibenzyl-4-phenyl homopiperazinyl, a 4- (4-trifluoromethylphenyl) -1 homopiperazinyl group, a 4- (4-trifluoromethoxyphenyl) -1 homopiperazinyl group, a 4- (4-chlorophenyl) -1 homopiperazinyl group, a group 4- (4-methoxyphenyl) -1 homopiperazinyl, a 4- (4-methylphenyl) -1 homopiperazinyl group, a 4- (2,4-dimethoxyphenyl) -1 homopiperazinyl group, a 4- (2,4-dimethylphenyl) group -1 homopiperazinyl, a 4- (2,4,6-trimethoxyphenyl) -1-homopiperazinyl group, a 4- (2,4-, 6-trimethylphenyl) -1- homopiperazinyl group, a 4- (3,4-dichlorophenyl) group ) -1- homopiperazinyl, a 4- (2,4,6,6-trifluorophenyl) -1- homopiperazinyl group, a 4- (4-bromophenyl) -1- homopiperazinyl group, a 4- (4-iodophenyl) -1-homopiperazinyl group, a 4- (4-fluorophenyl) -1-homopiperazinyl group, a 4- (4-trifluoromethoxybenzyloxycarbonyl) group -1-homopiperazinyl, a 4- (4-chlorobenzyloxycarbonyl) -1-homopiperazinyl group, a 4- (4-methoxybenzyloxycarbonyl) -1-homopiperazinyl group, a 4- (4-bromobenzyloxycarbonyl) -1-homopiperazinyl group, a group 4 - (4-methylbenzyloxycarbonyl) -1-homopiperazinyl, a 4- (2,4-dichlorobenzyloxycarbonyl) -1-homopiperazinyl group, a 4- (3,4-dimethoxybenzyloxycarbonyl) -1-homopiperazinyl group, a group 4- (2, 4, β-trifluorobenzyloxycarbonyl) -1-homopiperazinyl, a 4- (3,4-dimethylbenzyloxycarbonyl) -1-homopiperazinyl group, a 4- (2,4,6-trimethoxybenzyloxycarbonyl) -1-homopiperazinyl group, a group 4- ( 2,4,6-trimethylbenzyloxycarbonyl) -1-homopiperazinyl, a 4- (4-iodobenzyloxycarbonyl) -1-homopiperazinyl group, a 4- (4-trifluoromethylbenzyloxycarbonyl) -1-homopiperazinyl group, a 4- ( 3,4-dichlorobenzyloxycarbonyl) -1-homopiperazinyl, a 4- (4-trifluoromethoxyphenylcarbamoyl) -1-homopiperazinyl group, a 4- (4-chlorophenylcarbamoyl) -1-homopiperazinyl group, a 4- (4-methoxyphenylcarbamoyl) -1 group -homopiperazinyl, a 4- (4-bromophenylcarbamoyl) -1-homopiperazinyl group, a 4- (4-methylphenylcarbamoyl) -1-homopiperazinyl group, a 4- (2,4-dichlorophenylcarbamoyl) -1-homopiperazinyl group, a group 4 - (3,4-dimethoxyphenylcarbamoyl) -1-homopiperazinyl, a 4- (2,4,6-trifluorophenylcarbamoyl) -1-homopiperazinyl group, a 4- (3,4-dimethylphenylcarbamoyl) -1-homopiperazinyl group, a group 4 - (2, 4, 6-trimethoxyphenylcarbamoyl) -1-homopiperazinyl, a group 4- (2, 4, 6-trimethylphenylcarbamoyl) -1-homopiperazinyl, a group 4- (4-iodophenylcarbamoyl) -1-homopiperazinyl, a 4- (4-trifluoromethylphenylcarbamoyl) -1-homopiperazinyl group, a group 3, -di (phenylcarbamoyl) -1-homopiperazinyl, a group 4- (2- (4- trifluoromethylphenyl) ethyl) -1-homopiperazinyl, and a 4- (3- (4-trifluoromethylphenyl) propyl) -1-homopiperazinyl group, provided that, in the homopiperazine ring, 1 to 3 groups selected from the following groups can be substituted: the C 1 -C 6 alkoxycarbonyl group described above, the C 1 -C 6 alkyl phenyl group described above [wherein, in the phenyl ring , 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can to be substituted], the phenyl group described above [wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], the alkoxycarbonyl Cl-Cβ phenyl group described above [wherein, in the phenyl ring, 1 to 5 groups, and preferably and 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], the phenylcarbamoyl group described above [wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and an alkoxy group C1-C6 substituted or unsubstituted with halogen can be substituted], the C2-C6 alkenyl group phenyl described above [which is unsubstituted, or which is composed of 1 or 2 phenyl groups, wherein 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted, and alkenyl groups containing 2 to 6 carbon atoms and having 1 to 3 double bonds), and the benzoyl group described above [wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected of the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted]. Examples of the 1, 2, 3, 4-tetrahydroisoquinolyl group (wherein, in the 1, 2, 3, 4-tetrahydroisoquinoline ring, at least one amino group can be substituted [wherein, in the amino group, at least one selected from the group consisting of a Cl-Cβ alkyl phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) and a Cl-Cß alkyl group can be substituted]), can include 1, 2, 3, 4-tetrahydroisoquinolyl groups such as a 1,2,3 group , 4-tetrahydrod-, 2-, 3-, 4-, 5-, 6-, 7- or 8-) isoquinolyl, a group 4, β-diamino-1,2,3,4-tetrahydro-2-isoquinolyl , a 4, 6, 7-triamino-l, 2, 3, 4-tetrahydro-2-isoquinolyl group, a 7- (N-methyl-N- (4-trifluoromethoxybenzyl) amino) -1,2,3 group, 4-tetrahydro-2-isoquinolyl, a 6- (4-trifluoromethoxyphenoxy) -1, 2 group , 3,4-tetrahydro-2-isoquinolyl, a 7- (N-methyl-N- (4-trifluoromethylbenzyl) amino) -1,2,3,4-tetrahydro-2-isoquinolyl group, a group 7- (N -methyl-N- (4-chlorobenzyl) amino) -1, 2, 3, 4-tetrahydro-2-isoquinolyl, a group 7- (N- (4-chlorobenzyl) amino) -1, 2,3, 4- tetrahydro-2-isoquinolyl, a 7- (N-methyl-N- (2,4,6-tri (trifluoromethoxy) benzyl) amino) -1,2,3,4-tetrahydro-2-isoquinolyl group, a group 7 - (N-methyl-N- (2,4-di (trifluoromethyl) benzyl) amino) -1,2,3,4-tetrahydro-2-isoquinolyl and a group 7- (N-methyl-N- (2 , 3-diiodobenzyl) amino) -1,2,3, 4-tetrahydro-2-isoquinolyl, provided that, in ring 1, 2, 3, 4-tetrahydroisoquinoline, 1 to 3 amino groups can be substituted [wherein, in the amino group, 1 to 2 groups selected from the group consisting of the Cl-alkyl group C phenyl described above (wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted by halogen can be substituted) and the C 1 -C 6 alkyl group described above can be substituted]. Examples of the oxazolyl group (wherein, in the oxazole ring, at least one selected from the following groups can be substituted: a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted], a C1-C6 alkyl group, and a piperidyl group [wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a group Cl-Cβ alkoxy substituted or unsubstituted by halogen can be substituted))), can include oxazolyl groups such as a (2-, 4- or 5-) oxazolyl group, a 4- (4-chlorophenyl) -2-oxazolyl group , a 4- (4-trifluoromethoxyphenyl) -2-oxazolyl group, a g 2- (4-trifluoromethylphenyl) -4-oxazolyl group, a 4- (4-trifluoromethylphenyl) -2-oxazolyl group, a 2- (4-trifluoromethoxyphenyl) -4-oxazolyl group, a 4- (3, 4-) group dichlorophenyl) -2-oxazolyl, a 5- (4-bromophenyl) -2-oxazolyl group, a 4- (4-fluorophenyl) -2-oxazolyl group, a 5- (4-iodophenyl) -2-oxazolyl group, a 2- (2,4,6-trifluorophenyl) -4-oxazolyl group, a 4- (4-methylphenyl) -2-oxazolyl group, a 4- (3-methoxyphenyl) -2-oxazolyl group, a 2- ( 3,4-dimethylphenyl) -5-oxazolyl, a 4- (2,4-dimethoxyphenyl) -2-oxazolyl group, a 4- (2,4,6-trimethylphenyl) -2-oxazolyl group, a 4- ( 3, 4, 5-trimethoxyphenyl) -2-oxazolyl, a 4,5-diphenyl-2-oxazolyl group, a 2,4-diphenyl-5-oxazolyl group, and a 4-methyl-5- (4- ( 4-trifluoromethoxyphenoxy) - (1-, 2- or 3-) piperidyl) -2-oxazolyl, provided that, in the oxazole ring, 1 or 2 groups selected from the following groups can be substituted: a phenyl group [in where, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], the alkyl group Cl-Cß described above, and the piperidyl group described below [wherein, in the piperidine ring, 1 to 3 phenoxy group can be substituted (wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected of the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted)). Examples of the isoindolinyl group (wherein, in the isoindoline ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and a substituted C1-Cβ alkoxy group or unsubstituted with halogen can be substituted) can include isoindolinyl groups such as a group (1-, 2-, 4- or 5-) isoindolinyl, a 4-chloro- (1-, 2-, 3-, 5-, 6- or 7-) -isoindolinyl, a 4-trifluoromethyl- (1-, 2-, 3-, 5-, ß- or 7-) -isoindolinyl group, a 4-trifluoromethoxy- (1-, 2-, 3-, 5-, ß- or 7 -) - isoindolinyl, a 5-methyl- (l-, 2-, 3-, 4-, 6- or 7 -) - isoindolinyl group, a 4-methoxy- group ( 1-, 2-, 3-, 5-, 6- or 7-) isoindolinyl, a 3, 4-difluoro- (1-, 2-, 5-, ß- or 7-) isoindolinyl group, a 4, 5, 6-trichloro (1-, 2-, 3- or 7-) isoindolinyl group , a 4, 5-dimethyl (1-, 2-, 3-, β- or 7-) isoindolinyl group, a 4, 5, 6-trimethyl- (1-, 2-, 3- or 7-) isoindolinyl group, a 4, 5-dimethoxy (1-, 2-, 3-, 6- or 7-) isoindolinyl group, a 4,5,6-trimethoxy (1-, 2-, 3- or 7-) isoindolinyl group, and a 1, 1-dimethyl-5-bromo- (2, 3-, 4-, 6- or 7-) isoindolinyl group, provided that, in the isoindoline ring, 1 to 3 groups selected from the group consisting of Halogen atom described above, the substituted or unsubstituted C 1 -C 6 alkyl group described above, and the substituted or unsubstituted C 1 -C 6 alkoxy group with halogen described above may be substituted. Examples of the piperazinyl group [wherein, in the piperazine ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1 -C6 substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted)) can include piperazinyl groups such as a (1-, 2- or 3-) piperazinyl group, a group 4 phenyl-1-piperazinyl, a 2,4-diphenyl-1-piperazinyl group, a 2,4,5-triphenyl-l-piperazinyl group, a 4- (4-trifluoromethoxyphenyl) -1- piperazinyl group, a group 4 - (4-trifluoromethylphenyl) -1-piperazinyl, a (4-chlorophenyl-1-piperazinyl) methyl group, a 4- (2,4-dichlorophenyl) -1-piperazinyl group, a group 4- (2,4,6 -trifluorophenyl) -1-pi? erazinyl, a 2,4-di (trifluoromethyl) phenyl-1-piperazinyl group, and a 2,4,6-tri (trifluoromethoxy) phenyl-1-piperazinyl group, provided that, in the piperazine ring, the phenyl groups 1 to 3 described above can be substituted (wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a substituted C 1 -C 6 alkyl group or not substituted by halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted). Examples of the thiazolyl group (wherein, in the thiazole ring, at least one selected from the following groups can be substituted: a Cl-Cβ phenoxy alkyl group [wherein, in the phenyl ring, at least one selected from the group consisting of of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted]; a phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen it can be replaced]; a C1-C3 alkyl phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted]; a group - (W?) or NR3A32 [where Wi I are the same as described above, and R31 and R32, which may be identical or different, each represents a hydrogen atom, Cl-Cß alkyl group, phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can to be substituted), or Cl-Cβ alkyl phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted by halogen, and a group Cl-Cβ alkoxy substituted or unsubstituted with halogen can be substituted)); a piperazinyl group [wherein, in the piperazine ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group) substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted)); a piperidyl group [wherein, in the piperidine ring, at least one selected from the group consisting of a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group Cl-Cβ substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) and a Cl-Cβ phenyl alkyl group can be substituted]; and a phenoxy group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and a substituted C1-Cβ alkoxy group or not substituted with halogen can be substituted]), can include thiazolyl groups such as a (2-, 4- or 5-) thiazolyl group, a 2- ((4-fluoromethoxyphenoxy) methyl) -4-thiazolyl group, a 4- group ((4-fluoromethoxyphenoxy) methyl) -2-thiazolyl, a 2- ((4-fluoromethylphenoxy) methyl) -4-thiazolyl group, a 2- ((4-chlorophenoxy) methyl) -4-thiazolyl group, a group 2 - ((3-methoxyphenoxy) methyl) -4-thiazolyl, a 2 - ((2-methylphenoxy) methyl) -5-thiazolyl group, a 2 - ((2,4-dimethoxyphenoxy) methyl) -5-thiazolyl group, a 2 - ((3,4-dimethylphenoxy) methyl) -4-thiazolyl group, a 5- ((2,4,6-trimethoxyphenoxy) methyl) -2-thiazolyl group, a 2- ((3,4, 5-trimethylphenoxy) methyl) -4-thiazolyl, a 2- ((2,4,6-trifluorophenoxy) methyl) -4-thiazolyl group, a 4- ((3,4-dichlorophene noxy) methyl) -2-thiazolyl, a 2- ((4-bromophenoxy) methyl) -4-thiazolyl group, a 2- ((4-iodophenoxy) methyl) -4-thiazolyl group, a group 4 - ((4 Fluorophenoxy) methyl) -2-thiazolyl, a 2,5-diphenoxymethyl-4-thiazolyl group, a 4,5-diphenoxymethyl-2-thiazolyl group, a 2- (4-fluorophenyl) -4-thiazolyl group, a group 4- (4-fluorophenyl) -2-thiazolyl, a 2- (4-chlorophenyl) -4-thiazolyl group, a 4- (4-chlorophenyl) -2-thiazolyl group, a 2- (4-trifluoromethylphenyl) - group 4-thiazolyl, a 2- (4-trifluoromethoxyphenyl) -4-thiazolyl group, a 4- (4-trifluoromethylphenyl) -2-thiazolyl group, a 4- (4-trifluoromethoxyphenyl) -2-thiazolyl group, a 2- group (3,4-dichlorophenyl) -4-thiazolyl, a 4- (3,4-dichlorophenyl) -2-thiazolyl group, a 4- (2,4,6-trifluorophenyl) -2-thiazolyl group, a 5- group (4-bromophenyl) -2-thiazolyl, a 5- (4-fluorophenyl) -4-thiazolyl group, a 2- (4-iodophenyl) -5-thiazolyl group, a 2- (4-methylphenyl) -4-thiazolyl group, a 2- (4-methoxyphenyl) -4-thiazolyl group, a 2- (2, 4-dimethylphenyl) -5-thiazolyl, a 4- (3,4-dimethoxyphenyl) -2-thiazolyl group, a 4- (2,4,6-trimethylphenyl) -5-thiazolyl group, a group 5- (3, 4,5-trimethoxyphenyl) -4-thiazolyl, a 2,4-diphenyl-5-thiazolyl group, a 4,5-diphenyl-2-thiazolyl group, a 2-phenyl-5-phenoxymethyl-4-thiazolyl group, a 2- (4-fluorobenzyl) -4-thiazolyl group, a 2- (4-chlorobenzyl) -4-thiazolyl group, a 2- (4-trifluoromethylbenzyl) -4-thiazolyl group, a 2- (4-trifluoromethoxybenzyl) group -4-thiazolyl, a 2- (3,4-dichlorobenzyl) -4-thiazolyl group, a 4- (2,4-, 6-trifluorobenzyl) -2-thiazolyl group, a 5- (4-bromobenzyl) -2 group -thiazolyl, a 5- (4-fluorobenzyl) -4-thiazolyl group, a 2- (4-iodobenzyl) -5-thiazolyl group, a 2- (4-methylbenzyl) -4-thiazolyl group, a 2- ( 4-methoxybenzyl) -4-thiazolyl, a 2- (2,4-dimethylbenzyl) -5-thiazolyl group, a 4- (3,4-dimet) group oxybenzyl) -2-thiazolyl, a 4- (2,4,6-trimethylbenzyl) -5-thiazolyl group, a 5- (3,4,5-trimethoxybenzyl) -4-thiazolyl group, a 2,4-dibenzyl group -5-thiazolyl, a 4,5-dibenzyl-2-thiazolyl group, a 2-benzyl-5-phenoxymethyl-4-thiazolyl group, a 4- (4-chlorobenzyl) amino-2-thiazolyl group, a 4- group (4-trifluoromethoxybenzyl) amino-2-thiazolyl, a 4- (4-trifluoromethylbenzyl) amino-2-thiazolyl group, a 4- (N-methyl-N- (4-chlorobenzyl) amino) -2-thiazolyl group, a 4- (N-methyl-N- (4-trifluoromethoxybenzyl) amino) -2-thiazolyl group, a 4- (N-methyl-N- (4-trifluoromethylbenzyl) amino) -2-thiazolyl group, a 4- ( 4-chlorophenyl) amino-2-thiazolyl, a 4- (4-trifluoro-ethoxyphenyl) amino-2-thiazolyl group, a 4- (4-trifluoromethylphenyl) amino-2-thiazolyl group, a 4- (N-methyl- N- (4-chlorophenyl) amino) -2-thiazolyl, a 4- (N-methyl-N- (4-trifluoromethoxyphenyl) amino) -2-thiazolyl group, a 4- (N-methyl-N- (4 -trifluoromethylphenyl) amino) -2-thiazolyl, a 4- (4-chlorobenzyl) aminomethyl-2- group thiazolyl, a 4- (4-trifluoromethoxybenzyl) aminomethyl-2-thiazolyl group, a 4- (4-trifluoromethylbenzyl) aminomethyl-2-thiazolyl group, a 4- (N-methyl-N- (4-chlorobenzyl) aminomethyl) group -2-thiazolyl, a 4- (N-methyl-N- (4-trifluoromethoxybenzyl) aminomethyl) -2-thiazolyl group, a 4- (N-methyl-N- (4-trifluoromethylbenzyl) aminomethyl) -2-thiazolyl group , a 4- (4-chlorophenyl) aminomethyl-2-thiazolyl group, a 4- (4-trifluoromethoxyphenyl) aminomethyl-2-thiazolyl group, a 4- (4-trifluoromethylphenyl) aminomethyl-2-thiazolyl group, a 4- group (N-methyl-N- (4-chlorophenyl) aminomethyl) -2-thiazolyl, a 4- (N-methyl-N- (4-trifluoromethoxyphenyl) aminomethyl) -2-thiazolyl group, a 4- (N-methyl) group -N- (4-trifluoromethylphenyl) aminomethyl) -2-thiazolyl, a 4- (4-bromobenzyl) amino-2-thiazolyl group, a 4- (4-methoxybenzyl) amino-2-thiazolyl group, a group 4- ( 4-methylbenzyl) amino-2-thiazolyl, a 4- (N-methyl-N- (3,4-dichlorobenzyl) amino) -2-thiazolyl group, a 4- (N-methyl-N- (2, 4 -dimethoxybenzyl) amino) -2-thiazolyl, a 4- (N-methyl-N- (3,4-dimethylbenzyl) amino) -2-thiazolyl group, a 4- (4-bromophenyl) amino-2-thiazolyl group, a 4- ( 4-methoxyphenyl) amino-2-thiazolyl, a 4- (4-methylphenyl) amino-2-thiazolyl group, a 4- (N-methyl-N- (3,4-dichlorophenyl) amino) -2-thiazolyl group, a 4- (N-methyl-N- (3, 4-dimethoxyphenyl) amino) -2-thiazolyl group, a 4- (N-methyl-N- (2,4-dimethylphenyl) amino) -2-thiazolyl group, a 4- (4-bromobenzyl) aminomethyl-2-thiazolyl group, a 4- (4-naethoxybenzyl) aminomethyl-2-thiazolyl group, a 4- (4-methylbenzyl) aminomethyl-2-thiazolyl group, a 4- ( N-methyl-N- (3,4-dichlorobenzyl) aminomethyl) -2-thiazolyl, a 4- (N-methyl-N- (4-methoxybenzyl) aminomethyl) -2-thiazolyl group, a 4- (N-) group methyl-N- (3,4-dimethylbenzyl) aminomethyl) -2-thiazolyl, a 4- (4-bromophenyl) aminomethyl-2-thiazolyl group, a 4- (4-methoxyphenyl) aminomethyl-2-thiazolyl group, 4- (4-methylphenyl) aminomethyl-2-thiazolyl, a 4- (N-methyl-N- (3,4-dichlorophenyl) aminomethyl) -2-thiazolyl group, a g rupo 4- (N-methyl-N- (2, 4-dimethoxyphenyl) minomethyl) -2-thiazolyl, a group 4- (N-methyl-N- (3,4-dimethylphenyl) aminomethyl) -2-thiazolyl, a 4- (4-fluorobenzyl) amino-2-thiazolyl group, a 4- (2,4,6-trimethoxybenzyl) group amino-2-thiazolyl, a 4- (3,4,5-trimethylbenzyl) amino-2-thiazolyl group, a 4- (N-methyl-N- (4-iodobenzyl) amino) -2-thiazolyl group, a 4- (N-methyl-N- (2,4,6-trifluorobenzyl) amino) -2-thiazolyl group, a 4- (N-methyl-N- (4-iodobenzyl) amino) -2-thiazolyl group, a 4- (4-fluorophenyl) amino-2-thiazolyl group, a 4- (2,4,6-trimethoxyphenyl) amino-2-thiazolyl group, a 4- (3,4,5-trimethylphenyl) amino-2- group thiazolyl, a 4- (N-methyl-N- (4-iodophenyl) amino) -2-thiazolyl group, a 4- (N-methyl-N- (2,4,6-trifluorophenyl) amino group) -2- thiazolyl, a 4- (4-fluorobenzyl) aminomethyl-2-thiazolyl group, a 4- (3,4,6-trimethoxybenzyl) aminomethyl-2-thiazolyl group, a 4- (2,4,6-trimethylbenzyl) aminomethyl group -2-thiazolyl, a 4- (N-methyl-N- (4-iodobenzyl) aminomethyl) -2-thiazolyl group, a 4- (N-methyl-N- (2,4,6-trifluorobenzyl) aminomethyl group) -2-tiazoli lo, a 4- (4-fluorophenyl) aminomethyl-2-thiazolyl group, a 4- (2,4,6-trimethoxyphenyl) aminomethyl-2-thiazolyl group, a 4- (3,4,5-trimethylphenyl) aminomethyl group -2-thiazolyl, a 4- (N-methyl-N- (4-iodophenyl) aminomethyl) -2-thiazolyl group, a 4- (N-methyl-N- (2,4,6-trifluorophenyl) aminomethyl) group -2-thiazolyl, a 4- (N-methyl-N- (4-trifluoromethylphenyl) aminomethyl) -2-thiazolyl group, a 4- (4-trifluoromethoxyphenoxy) -2-thiazolyl group, a 4- (4-trifluoromethylphenoxy) group ) -2-thiazolyl, a 4- (4-chlorophenoxy) -2-thiazolyl group, a 4- (3,4-dichlorophenoxy) -2-thiazolyl group, a 4- (4-methoxyphenoxy) -2-thiazolyl group, a 4- (4-methylphenoxy) -2-thiazolyl group, a 4- (3,4-dimethoxyphenoxy) -2-thiazolyl group, a 5- (2,4-dimethylphenoxy) -4-thiazolyl group, a 4- group (2,4,6-trimethoxyphenoxy) -5-thiazolyl, a 4- (3,4-trimethylphenoxy) -2-thiazolyl group, a 4- (4-fluorophenoxy) -2-thiazolyl group, a 2- group (4-bromophenoxy) -5-thiazolyl, a 2- (4-iodophenoxy) -4-thiazolyl group, a group 5- (2,4,6-trifluorophenoxy) -2-thiazolyl, a 4- (4- (4-trifluoromethylphenyl) -1-piperazinyl) -2-thiazolyl group, a 4- (4- (4-trifluoromethoxyphenyl) group) -1-piperazinyl) -2-thiazolyl, a 4- (4- (4-chlorophenyl) -1-piperazinyl) -2-thiazolyl group, a 4- (4- (4-trifluoromethylphenoxy) -1-piperazinyl) - 2-thiazolyl, a 4- (4- (4-trifluoromethoxyphenoxy) -1-piperazinyl) -2-thiazolyl group, a 4- (4- (4-chlorophenoxy) -1-piperazinyl) -2-thiazolyl group, a group 5- (3, 4-diphenyl-1-piperazinyl) -2-thiazolyl, a 2- (3,4,5-triphenyl-l-piperazinyl) -4-thiazolyl group, a 5- (3, 4, 5) group -trifenoxi-1-piperazinyl) -4-thiazolyl, a 4- (3,4-diphenoxy-1-piperazinyl) -5-thiazolyl group, a 4- (4- (4-trifluoromethoxy-phenyl) -1-piperazinyl) group - 5-phenoxy-2-thiazolyl, a 4- (4- (4-trifluoromethoxyphenoxy) -1-piperazinyl) -5-phenoxy-2-thiazolyl group, a 4-phenyl-2-thiazolyl group, a 2-phenyl- group 4-thiazolyl, and a 2- (4-benzyl- (1-, 2- or 3-) piperidyl) - (4- or 5-) thiazolyl group, provided that, in the thiazole ring, 1 or 2 groups selected from the following groups can be substituted: the Cl-Cβ phenoxy alkyl group described above [wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a C 1-7 alkoxy group Cß substituted or unsubstituted with halogen can be substituted]; the phenyl group described above [wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted]; the Cl-Cβ phenyl alkyl group described above [wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted]; a group - (Wi) or NR31R32 [where Wi I are the same as described above, and R31 and R32, which may be identical or different, each represents a hydrogen atom, the C1-C6 alkyl group described above, the phenyl group described above (wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), or the Cl-Cβ phenyl alkyl group described above (wherein, in the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group which consists of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted)); the piperazinyl group described above [wherein, in the piperazine ring, at least 1 to 3 phenyl groups can be substituted (wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-Cβ alkoxy group substituted or unsubstituted by halogen can be substituted)); the piperidyl group described above [wherein, in the piperidine ring, 1 to 3 groups selected from the group consisting of a phenoxy group (wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group which consists of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) and the Cl-Cβ phenyl alkyl group described above can be replaced]; and a phenoxy group [wherein, on the phenyl ring, 1 to 5 groups, and preferably 1 to 3 groups selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted]. A Cl-Cß alkyl group substituted with naphthyl (wherein, in the naphthalene ring, at least one Cl-Cβ alkoxy group can be substituted) includes, in addition to Cl-Cß alkyl group substituted with naphthyl as described above, an alkyl group Cl-Cβ naphthyl (wherein, in the naphthalene ring, 1 to 4 Cl-Cβ alkoxy groups can be substituted), for example, an example 2- (6-methoxy-2-naphthyl) methyl, group (4-methoxy) 1-naphthyl) methyl, 2- (4-methoxy-1-naphthyl) ethyl group, (4-methoxy-1-naphthyl) methyl group, 2- (3-ethoxy-1-naphthyl) ethyl group, 2-n group -propoxy-l-naphthylmethyl, 5-tert-butoxy-2-naphthyl methyl group, 6-n-pentyloxy-3-naphthylmethyl group, 7- n-hexyloxy-4-naphthylmethyl group, 2- (2,4-dimethoxy) group -l-naphthyloxy) ethyl, 2- (1, 1, 4, 4-tetramethoxy-5-naphthioloxy) ethyl group or the like. An imidazolyl group (wherein, in the imidazole ring, at least one selected from the group consisting of a halogen atom and a nitro group can be substituted) includes an imidazolyl group (wherein, on the imidazole ring, 1 to 3 substituents selected from the group consisting "of a halogen atom and a nitro group can be substituted), for example, a (1-, 2-, 4- or 5-) imidazolyl group, 2-chloro-4-nitro- group ( l- or 5-) imidazolyl, 2-bromo- (1 -, 4 or 5) imidazolyl group, 4-fluoro- (1, 2 or 5) imidazolyl group, 2, 5-dichloro group (1 - or 4-) imidazolyl, group 2, 4, 5-trichloro-1-imidazolyl, 2-nitro- (1 -, 4 or 5) imidazolyl group, 4-nitro- group (1, 2 or 5) -) imidazolyl, group 2, 5-dinitro- (1- or 4-) imidazolyl, group 2, 4, 5-trinitro-1-imidazolyl or the like. A C 1 -C 3 alkyl group phenyl (wherein, on the phenyl ring) , at least one selected from the group consisting of a benzofuryl group, a halogen atom, a Cl-Cß alkyl group either substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) includes, in addition to a Cl-Cβ phenyl alkyl group as described above (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cβ phenyl alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl portion (wherein in the phenyl ring, 1 to 5 preferably 1 to 3 substituents selected from the group consisting of a benzofuryl group, a halogen atom, a substituted or unsubstituted C 1 -C 6 alkyl group with halogen and a substituted or unsubstituted C 1 -C 6 alkoxy group halogen can be substituted), for example, a group 4- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) benzyl, group 2- ((2-, 3-, 4- , 5-, 6- or 7-) benzofuryl) benzyl, group 3- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) benzyl , group 2, 4-di ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) benzyl, group 2, 4, 6-tri ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) benzyl, 2-trifluoromethyl-4- (2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) benzyl group 3-trifluoromethoxy-4- group (2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) benzyl, group 4-chloro-3- (2-, 3-, 4-, 5-, 6- or 7-) benzofuril ) benzyl or similar. A Cl-Cß furyl alkyl group [wherein, in the furan ring, at least one phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group) substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes a Cl-Cß furyl alkyl group having a straight or branched alkyl group containing 1 to ß atoms of carbon in the alkyl moiety [wherein, in the furan ring, 1 to 3 phenyl groups as described above (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of one atom of halogen, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), for example, a (2- or 3-) furylmethyl group can be substituted) , group l - ((2- or 3-) furyl) ethyl, 2- ((2- or 3-) furyl) ethyl group, 3- ((2- or 3-) furyl) propyl group, 2- (2 - or 3-) furyl) propyl, group 4- ((2-or 3-) furyl) butyl, 5- ((2- or 3-) furyl) pentyl, group 4- ((2- or 3-) furyl ) pentyl, group 6- ((2- or 3-) furyl) hexyl, 1,1-dimethyl-2- ((2- or 3-) furyl) ethyl, group 2-methyl-3- ((2- or 3-) furyl) propyl, 2- (4-chlorophenyl) - (3-, 4- or 5-) furylmethyl group 2- (2-chloro-5-trifluoromethylphenyl) - (3-, 4- or 5-) ) furylmethyl, 2- (4-trifluoromethoxyphenyl) - (3-, 4- or 5-) furylmethyl group, 2- (2,4-dichlorophenyl) - (3-, 4- or 5-) furylmethyl group 2- group (2,4,6-trifluorophenyl) - (3-, 4- or 5-) furylmethyl, 2- (4-methylphenyl) - (3-, 4- or 5-) furylmethyl group 2- (4-methoxyphenyl) ) - (3-, 4- or 5-) furylmethyl, 2- (2,4-dimethylphenyl) - (3-, 4- or 5-) furylmethyl group, 2- (3,4-dimethoxyphenyl) - (3) group -, 4- or 5-) furylmethyl, 2- (2, 4, 6-trimethylphenyl) - (3-, 4- or 5-) furylmethyl group, 2- (3,4,5-trimethoxyphenyl) group ) - (3-, 4- or 5-) furylmethyl, 2,4-diphenyl (3- or 5-) furylmethyl group, 2, 4, 5-triphenyl-3-furylmethyl group or the like. A C 1 -C 6 alkyl pyridyl group [wherein, in the pyridine ring, at least one selected from the group consisting of a furyl group and a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes, in addition to a C1-C6 alkyl pyridyl group as described above, a C 1 -C 6 alkyl pyridyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl moiety [wherein, in the pyridine ring, 1 to 3 substituents selected from the group consisting of a furyl group and a phenyl group as described above (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from group consisting of a benzofuryl group, a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted], for example, a 3- (2- or 3-) furyl- (2-, 4-, 5- or 6-) pyridylmethyl group, 2- (4-trifluoromethoxyphenyl) - (3-, 4-, 5- or 6-) group pyridylmethyl, 2- (4-trifluoromethylphenyl) - (3-, 4-, 5- or 6-) pyridylmethyl group, 2- (4-methoxyphenyl) - (3-, 4-, 5- or 6-) pyridylmethyl group, 2- (4-methylphenyl) - (3-, 4-, 5- or 6-) pyridylmethyl group, 2- (3-chloro-4-fluorophenyl) - (3-, 4-, 5- or 6-) group pyridylmethyl, 2- (2,4-dimethoxyphenyl) - (3-, 4-, 5- or 6-) pyridylmethyl group 2- (3, 4, 5-trimethoxyphenyl) - (3-, 4-, 5- or 6-) pyridylmethyl, 2- (2,4-dimethylphenyl) - (3-, 4-, 5- or 6-) pyridyl methyl group 2- (2, 4, 6-trimethylphenyl) - (3-, 4-, 5- or 6-) pyridylmethyl, 2- (2, 4, β-trichlorophenyl) - (3-, 4-, 5- or 6-) group ) pyridylmethyl, 2- (3-chloro-4-trifluoromethoxyphenyl) - (3-, 4-, 5- or 6-) pyridylmethyl, group 2, 4-di (2- or 3-) furyl (5- or 6) -) pyridylmethyl, group 2, 4,6-triphenyl (3- or 5-) pyridylmethyl, 2-furyl-5-phenyl (3-, 4- or 6-) pyridylmethyl group or the like. A C 1 -C 6 alkyl benzothienyl group (wherein, in the benzothiophene ring, at least one halogen atom can be substituted) includes a C 1 -C 6 alkyl group substituted with benzothienyl which can be substituted by 1 to 3 halogen atoms in the ring benzofuran, for example, a 2-benzothienylmethyl group, 1- (2-benzothienyl) ethyl group, 2- (4-benzothienyl) ethyl group, 3- (5-benzothienyl) propyl group, 4- (6-benzothienyl) butyl group , 5- (7-benzothienyl) pentyl group, 6- (2-benzothienyl) hexyl group, 4-fluoro-2-benzothienylmethyl group, 5-fluoro-2-benzothienylmethyl group, 6-fluoro-2-benzothienylmethyl group, group 7 -fluoro-2 ~ benzothienylmethyl, 4-chloro-2-benzothienylmethyl group, 5-chloro-2-benzothienylmethyl group, 6-chloro-2-benzothienylmethyl group, 7-chloro-2-benzothienylmethyl group, 4-bromo-2- group benzothienylmethyl, 5-bromo-2-benzothienylmethyl group, 6-bromo-2-benzothienylmethyl group, 7-bromo-2-benzothienylmethyl group, 4-iodo-2-benzothienylmethyl group, 5-iodo-2-benzothien group ilmethyl, 6-iodo-2-benzothienylmethyl group, 7-iodo-2-benzothienylmethyl group, 4-fluoro-3-benzothienylmethyl group, 5-fluoro-3-benzothienylmethyl group, 6-fluoro-3-benzothienylmethyl group, group 7 fluoro-3-benzothienylmethyl, 4-chloro-3-benzothienylmethyl group, 5-chloro-3-benzothienylmethyl group, 6-chloro-3-benzothienylmethyl group, 7-chloro-3-benzothienylmethyl group, 4-bromo-3-benzothienylmethyl group , 5-bromo-3-benzothienylmethyl group, 6-bromo-3-benzothienylmethyl group, 7-bromo-3-benzothienylmethyl group, 4-iodo-3-benzothienylmethyl group, 5-iodo-3-benzothienylmethyl group, 6-iodo group -3-benzothienylmethyl, 7-iodo-3-benzothienylmethyl group, 2- (4-fluoro-2-benzothienyl) ethyl group, 2- (5-fluoro-2-benzothienyl) ethyl group, 2- (6-fluoro-) group 2-benzothienyl) ethyl, 2- (7-fluoro-2-benzothienyl) ethyl group, 2- (4-chloro-2-benzothienyl) ethyl group, 2- (5-chloro-2-benzothienyl) ethyl group 2 - (6-chloro-2-benzothienyl) ethyl, 2- (7-chloro-2-benzothienyl) ethyl group, 2- (4-fluoro-3-benzothienyl) group m ethyl, 2- (5-fluoro-3-benzothienyl) methyl group, 2- (6-fluoro-3-benzothienyl) ethyl group, 2- (7-fluoro-3-benzothienyl) ethyl group, 2- (4- group chloro-3-benzothienyl) ethyl, 2- (5-chloro-3-benzothienyl) ethyl group, 2- (6-chloro-3-benzothienyl) ethyl group, 2- (7-chloro-3-benzothienyl) ethyl group, 2- (4-fluoro-2-benzothienyl) ethyl group, 6- (5-fluoro-2-benzothienyl) hexyl group, 6- (6-fluoro-2-benzothienyl) hexyl group, 6- (7-fluoro-) group 2-benzothienyl) exoyl, 6- (4-chloro-2-benzothienyl) hexyl group, 6- (5-chloro-2-benzothienyl) hexyl group, 6- (6-chloro-2-benzothienyl) hexyl group, 6- (7-chloro-2-benzothienyl) hexyl group, 6- (4-fluoro-3-benzothienyl) methyl group, 6- (5-fluoro) group -3-benzothienyl) hexyl, 6- (6-fluoro-3-benzothienyl) hexyl group, 6- (7-fluoro-3-benzothienyl) hexyl group, 6- (4-chloro-3-benzothienyl) hexyl group, group 6- (5-chloro-3-benzothienyl) hexyl, 6- (6-chloro-3-benzothienyl) hexyl group, 6- (7-chloro-3-benzothienyl) hexyl group, (2, 4-dibromo-3) group benzothienyl) methyl, group (4,5,6-trichloro-3-benzothienyl) methyl or the like. A C2-C6 alkenyl benzofuryl group (wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a substituted C1-C6 alkoxy group or unsubstituted with halogen can be substituted) includes a benzofuryl group, which is a group consisting of a benzofuryl group substituted or unsubstituted by 1 to 3 substituents selected from the group consisting of a halogen atom, an alkyl group Cl- Cβ substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, and a straight or branched alkenyl group containing 2 to 6 carbon atoms and having 1 to 3 double bonds s. The C2-C6 alkenyl group benzofuryl includes both trans and cis forms. The C2-C6 alkenyl benzofuryl group includes 2- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) vinyl, group 3- ((2-, 3-, 4-, 5) -, 6- or 7-) benzofuryl) -2-propenyl, group 3- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) -2-methyl-2-propenyl, group 4- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) -2-butenyl, group 4- ((2-, 3-, 4-, 5-, 6- or 7) -) benzofuryl) -3-butenyl, group 4- ((2-, 3-, 4-, 5-, ß- or 7-) benzofuryl) -1,3-butadiyl, group 5- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) -1, 3, 5-hexatrienyl, group 6- ((2-, 3-, 4-, 5-, ß- or 7-) benzofuryl ) -1,3-hexadienyl, group 3- (6-trif luoromethyl) 2- (2-, 3-, 4-, 5- or 7-) benzofuryl) -2-propenyl, group 3- (5-trifluoromethoxy) (2-, 3-, 4-, 5- or 7-) benzofuryl) -2-propenyl, group 3- (7-chloro- (2-, 3-, 4-, 5- or 7-) benzofuryl) - 2-propenyl, 3- (2, 6-dimethyl- (3-, 4-, 5- or 7-) benzofuryl) -2-propenyl group, 3- (3, β-dimethoxy (2-, 3-, 4-, 5- or 7-) benzofuryl) -2-propenyl, group 3- (4,5, ß-trimethyl (2-, 3- or 7-) benzofuryl) -2 -pro penyl, group 3- (3, 5, 6-trimethoxy (2-, 4- or 7-) benzofuryl) -2-propenyl, group 3- (3-chloro-6-trifluoromethyl (2-, 3-, 4- , 5- or 7-) benzofuryl) -2-propenyl or the like.

A thiazolyl group [wherein, in the thiazole ring, at least one phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group) with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes a thiazolyl group [wherein, in the thiazole ring, 1 to 2 phenyl groups as described above (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted C 1 -C 6 alkyl group with halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen can can be substituted), for example, a (2-, 4- or 5-) thiazolyl group, 4-phenyl- (2- or 5-) thiazolyl group, 2-phenyl- (4- or 5-) group ) thiazolyl, 5-phenyl- (2- or 4-) thiazolyl group, 2, 5-diphenyl-4-thiazolyl group, 2,4-diphenyl-5-thiazolyl, 2- (4-trifluoromethylphenyl) - (4- or 5-) thiazolyl group, 2- (4-trifluoromethoxy-phenyl) - (4- or 5-) thiazolyl group, 2- group (4-chlorophenyl) - (4- or 5-) thiazolyl, 2- (3-chloro-4-trifluoromethylphenyl) - (4- or 5-) thiazolyl group, 2- (4-methylphenyl) - (4- 5-) thiazolyl, 2- (2,4-dimethylphenyl) - (4- or 5-) thiazolyl group, 2- (3,4,6-trimethylphenyl) - (4- or 5-) thiazolyl group, 2- group (4-methoxyphenyl) - (4- or 5-) thiazolyl, 2- (2,4-dimethoxyphenyl) - (4- or 5-) thiazolyl group, 2- (3, 6-trimethoxyphenyl) - (4-) group or 5-) thiazolyl, 2- (2,4-dichlorophenyl) - (4- or 5-) thiazolyl group, 2- (3,4-, 6-trifluorophenyl) - (4- or 5-) thiazolyl group or the like. An isoindolinyloxy group [wherein, in the isoindoline ring, at least one selected from the group consisting of a Cl-Cβ alkoxycarbonyl group, Cl-Cβ alkyl phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a benzofuryl group, a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted or unsubstituted Cl-Cβ alkoxy group with halogen can be substituted), a C2-C6 alkenyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C3 alkyl group substituted or unsubstituted with halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen can be substituted), a C 1 -C 6 alkyl furyl group [wherein, in the furan ring, at least one phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted], a C1-6 alkyl group C6 pyridyl [e n wherein, in the pyridine ring, at least one selected from the group consisting of a furyl group and a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a benzofuryl group, a halogen atom , a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted], a Cl-Cß benzofuryl alkyl group (wherein, in the benzofuran ring , at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl- alkyl group Cβ benzothienyl (wherein, in the benzothiophene ring, at least one halogen atom can be substituted), a C 2 -C 6 alkenyl benzofuryl group (wherein, in the benzofuryl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a thiazolyl group [wherein, in the thiazole ring, at least one phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen can be substituted) can be substituted] and a Cl-Cβ phenoxy alkyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a group substituted or unsubstituted Cl-Cβ alkyl with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes an isoindolinyloxy group [wherein, in the isoindoline ring, 1 to 3 substituents selected from a group consisting of a straight or branched C 1 -C 6 alkoxycarbonyl group containing 1 to 6 carbon atoms as described above, a C 1 -C 3 alkyl phenyl group having a straight or branched alkyl group in the group alkyl moiety as described above (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a benzofuryl group, a halogen atom, a substituted or unsubstituted Cl-Cβ alkyl group with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted), a C2-C6 alkenyl group phenyl having a straight or branched alkenyl group containing 2 to 6 carbon atoms in the alkenyl portion and having 1 to 3 double bonds as described above, and includes both trans and cis forms (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, an alkyl group Cl-Cβ substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cß furyl alkyl group having a straight or branched alkyl group Figure imgf000014_0001 wherein the filo ring contains 1 to 6 carbon atoms in the alkyl portion as described above [wherein, in the furan ring, 1 to 3 phenyl groups (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted], an alkyl group Cl- Cβ pyridyl having a straight or branched alkyl group containing 1 to β carbon atoms in the alkyl moiety as described above [wherein, in the pyridine ring, 1 to 3 substituents selected from the group consisting of a furyl group and a phenyl group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a benzofuryl group, a halogen atom, a substituted Cl-Cβ alkyl group or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted], a Cl-Cß benzofuryl alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl portion as described above (wherein, in the benzofuran ring, 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and an alkoxy Cl group -Cβ substituted or unsubstituted with halogen can be substituted), a Cl-Cβ benzothienyl alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl portion as described above (wherein, in the benzothiophene ring, 1 to 3 halogen atoms can be substituted), a C2-C6 alkenyl benzofuryl group having a straight or branched alkenyl group containing 2 to ß atoms of carbon in the alkenyl portion and having 1 to 3 double bonds as described above, and includes both trans and cis forms (wherein, in the benzofuran ring, 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and an alkoxy Cl group Cβ substituted or unsubstituted with halogen can be substituted), a thiazolyl group as described above [wherein, in the thiazole ring, 1 to 2 phenyl groups (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] and an alkyl Cl group -Cß phenoxy having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl moiety as described above (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 su bitumen selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted, for example, a group (1-, 2-, 3- or 4-) isoindolinyloxy, a 1-tert-butoxycarbonyl- (2-, 3- or 4-) isoindolinyloxy group, a group 1- (2- (4-chlorophenyl) - ( 3-, 4- or 5-) furylmethyl) - (2-, 3- or 4-) isoindolinyloxy, a group 1- (2- (2-chloro-5-trifluoromethylphenyl) - (3-, 4- or 5- ) furylmethyl) - (2-, 3- or 4-) isoindolinyloxy, a 1- (3-trifluoromethyl-4-chlorobenzyl) - (2-, 3- or 4-) isoindolinyloxy group, a group l- (4- ( (2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) benzyl) - (2-, 3- or 4-) isoindolinyloxy, a group l- (3 - ((2- or 3- ) furyl) - (2-, 4-, 5- or 6-) pyridylmethyl) - (2-, 3- or 4-) isoindolinyloxy, a group 1- (2- (4-trifluoromethoxyphenyl) - (3-, 4) -, 5- or 6-) pyridylmethyl) - (2-, 3- or 4-) isoindolinyloxy, a group 1- (2- (3-chloro-4-fluor ofenyl) - (3-, 4-, 5- or 6-) pyridylmethyl) - (2-, 3- or 4-) isoindolinyloxy, a group 1- (6-trifluoromethyl (2-, 3-, 4-, 5 - or 7-) benzofurylmethyl) - (2-, 3- or 4-) isoindolinyloxy, a group 1- (5-chloro- (2-, 3-, 4-, 6- or 7-) benzothienylmethyl) - (2 -, 3- or 4-) isoindolinyloxy, a 1- (6-chloro (2-, 3-, 4-, 5-, or 7-) benzofurylmethyl) - (2-, 3- or 4-) isoindolinyloxy group, a 1- (5-trifluoromethoxy (2-, 3-, 4-, 6- or 7-) benzofurylmethyl) - (2-, 3- or 4-) isoindolinyloxy group, an l- (3- (6-trifluoromethyl) group (2-, 3-, 4-, 5- or 7-) benzofuryl) -2-propenyl) - (2-, 3- or 4-) isoindolinyloxy, a group 1- (5-chloro- (2-, 3 -, 4-, 6- or 7-) benzofurylmethyl) - (2-, 3- or 4-) isoindolinyloxy, a 1- (2- (4-trifluoromethylphenyl) - (4- or 5-) thiazolylmethyl) - (2- , 3- or 4-) isoindolinyloxy, an l- (2- (4-trifluoromethoxyphenoxy) ethyl) - (2-, 3- or 4-) isoindolinyloxy group, a 1,3-diethoxycarbonyl- (2- or 4-) group Isoindolinyloxy, a group 2-Phenoxymethyl-4- ((2-, 3-, 4-, 5-, 6- or 7-) benzofurylmethyl) - (1-, 3-, 5-, 6- or 7-) isoindolinyloxy, a group 2 - ((2- or 3-) furylmethyl) -4,5-dimethoxycarbonyl- (1-, 3-, 6- or 7-) isoindolinyloxy or the like. A benzothiazolidinyloxy group [wherein, in the benzothiazolidine ring, at least one selected from the group consisting of an oxo group and a C1-C6 alkyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of of a halogen atom, a substituted or unsubstituted C1-C6 alkyl group with halogen and a substituted or unsubstituted C1-C6 alkoxy group with halogen can be substituted) can be substituted] includes a benzothiazolidinyloxy group [wherein, in the ring benzothiazolidine, 1 to 3 substituents selected from the group consisting of an oxo group and a C1-C6 alkyl group phenyl having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl portion as described above (in where, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted C1-C6 alkyl group with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted, for example, a (2-, 3-, 4-, 5-, 6- or 7-) benzothiazolidinyloxy group, a group 3 (4-trifluoromethoxybenzyl) -2-oxo- (4-, 5-, 6- or 7-) benzothiazolidinyloxy, a 3- (4-trifluoromethylbenzyl) - (2-, 4-, 5-, 6- 7-) benzothiazolidinyloxy, a 3- (4-chlorobenzyl) - (2-, 4-, 5-, 6- or 7-) benzothiazolidinyloxy group, a 3- (4-methylbenzyl) - (2-, 4-, 5-, 6- or 7-) benzothiazolidinyloxy, a 3- (3,4-dimethylbenzyl) - (2-, 4-, 5-, 6- or 7-) benzothiazolidinyloxy group, a group 3- (2, 4, 6-trimethylbenzyl) - (2-, 4-, 5-, 6- or 7-) benzothiazolidinyloxy, a 3- (4-methoxybenzyl) - (2-, 4-, 5-, ß- or 7-) benzothiazolidinyloxy group , a 3- (3,4-dimethoxybenzyl) - (2-, 4-, 5-, 6- or 7-) benzothiazolidinyloxy group, a 3- (3,4-trimethoxybenzyl) - (2-4) group -, 5-, 6- or 7-) benzothiazolidinyloxy, a 3- (4-fluorobenzyl) - (2-, 4-, 5-6- or 7-) benzothiazolidinyloxy group, a group 3 - (3, 4-dichlorobenzyl) - (2-, 4-, 5-, 6- or 7-) benzothiazolidinyloxy, a 3- (2,4,6-trifluorobenzyl) - (2-, 4-, 5-) group , 6- or 7-) benzothiazolidinyloxy, a 2-oxo- (2-, 4-, 5-, 6- or 7-) benzothiazolidinyloxy group, a 2,3-dibenzyl group (4-, 5-, 6- or 7-) benzothiazolidinyloxy, a 2, 3, 5-tribenzyl (4-, 5-, 6- or 7-) benzothiazolidinyloxy group or the like. An indolyloxy group [wherein, in the indole ring, at least one C1-C6 alkyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group) substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes an indolyloxy group [wherein, in the indole ring, 1 to 3 C1-C6 alkyl groups phenyl which has a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl portion as described above (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of one atom of halogen, a C1-C6 alkyl group substituted or unsubstituted by halogen and a C1-C6 alkoxy group substituted or unsubstituted by halogen can be substituted), for example, a group (1-, 2-, 3) can be substituted -, 4-, 5-, 6- or 7-) indole Ilyloxy, an l- (4-trifluoromethoxybenzyl) - (2-, 3-, 4-, 5-, 6- or 7-) indolyloxy group, a 1- (4-trifluoromethylbenzyl) - (2-, 3-, 4-, 5-, 6- or 7-) indolyloxy, a group 1- (4-chlorobenzyl) - (2-, 3-, 4-, 5-, 6- or 7-) indolyloxy, a group 2- (4-methylbenzyl) - (1-, 3-, 4 -, 5-, 6- or 7-) indolyloxy, a 3- (3,4-dimethylbenzyl) - (1-, 2-, 4-, 5-, 6- or 7-) indolyloxy group, a 4- group (2, 4, 6-trimethylbenzyl) - (1-, 2-, 3-, 5-, 6- or 7-) indolyloxy, a 5- (4-methoxybenzyl) - (1-, 2-, 3-) group , 4-, 6- or 7-) indolyloxy, a group ß- (3,4-dimethoxybenzyl) - (1-, 2-, 3-, 4-, 5- or 7-) indolyloxy, a group 7- ( 3, 4, 5-trimethoxybenzyl) - (1-, 2-, 3-, 4-, 5- or 6-) indolyloxy, a 1- (4-fluorobenzyl) - (2-, 3-, 4-, 5-, 6- or 7-) indolyloxy, a 1- (3,4-dichlorobenzyl) - (2-, 3-, 4-, -, 6- or 7-) indolyloxy, a 1- (2,4,6-trifluorobenzyl) - (2-, 3-, 4-, 5-, 6- or 7-) indolyloxy group, a group 1, 3-dibenzyl (2-, 4-, 5-, 6- or 7-) indolyloxy, a 1,3,5-tribenzyl (2-, 4-, 6- or 7-) indolyloxy group or the like. A pyrrolidinyl group [wherein, in the pyrrolidine ring, at least one amino group (wherein, in the amino group, at least one selected from the group consisting of a C1-C6 alkyl group and a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted ) is substituted] includes a pyrrolidinyl group [wherein, on the pyrrolidine ring, 1 to 3 amino groups (wherein, at the amino group, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of an alkyl group C1 -C6 as described above and a phenyl group as described above (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted by halogen can be substituted) can be substituted) are, for example, substituted by a 3- (N-methyl-N- (3,4-dichlorophenyl) amino) - (1-) group , 2-, 4- or 5-) pyrrolidinyl, a 3-amino- (l-, 2-, 4- or 5-) pyrrolidinyl group, a 2, 3-diamino- group (1-, 4- or 5-) ) pyrrolidinyl, a 2, 3, 5-triamino- (1- or 4-) pyrrolidinyl group, a 3- (N-methyl-N- (4-methylphenyl) amino) - (1-, 2-, 4-) group or 5-) pyrrolidinyl, a 3- (N-ethyl-N- (3-methoxyphenyl) amino) - (1-, 2-, 4- or 5-) pyrrolidinyl group, a group 3- (N- (4-trifluoromethylphenyl) amino) - (1-, 2-, 4- or 5-) pyrrolidinyl, a group 3- (N- (4-trifluoromethoxyphenyl) amino) - (1-, 2-, 4- or 5-) pyrrolidinyl, a 3- (N-methyl-N- (3,4-, 5-trifluorophenyl) amino) - (1-, 2-, 4- or 5-) pyrrolidinyl group, a 3- group (N-methyl-N- (3-chloro-4-trifluoromethylphenyl) amino) - (1-, 2-, 4- or 5-) pyrrolidinyl, a 3- (N-phenylamino) - (1-, 2-) group , 4- or 5-) pyrrolidinyl, a 3-methylamino- (1-, 2-, 4- or 5-) pyrrolidinyl group, a 3-methylamino (1-, 2-, 4- or 5-) pyrrolidinyl group or Similar. An indolinyl group (wherein, in the indoline ring, at least one halogen atom can be substituted) includes an indolinyl group (wherein, in the indoline ring, 1 to 3 halogen atoms can be substituted), for example, a group (1-, 2-, 3-, 4-, 5-, 6- or 7-) indolinyl, a group 5-bromo ~ (l-, 2-, 3-, 4-, ß- or 7-) indolinyl, a 4-chloro- (1-, 2-, 3-, 5-, 6- or 7-) indolinyl group, a 6-fluoro- (1-, 2-, 3-, 4-, 5- or 7-) indolinyl, a 5, 7-dichloro- (1-, 2-, 3-, 4- or 6-) indolinyl group, a 3, 5, 6-trifluoro- (1-, 2-, 4- -7-) indolinyl or the like. An indolinyloxy group [wherein, in the indoline ring, at least one selected from the group consisting of a Cl-Cß phenyl alkyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom , a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted) and an oxo group can be substituted] includes an indolinyloxy group [wherein, in the indoline ring , 1 to 3 substituents selected from the group consisting of a Cl-Cß phenyl alkyl group having a straight or branched alkyl group containing 1 to β carbon atoms in the alkyl moiety as described above (wherein, in the ring phenyl, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted Cl-Cβ alkoxy group or not substituted with halogen can be substituted) and an oxo group can be substituted], for example, a (1-, 2-, 3-, 4-, 5-, 6- or 7-) indolinyloxy group, a 1- (4-trifluoromethoxybenzyl) -2, 3- dioxo (l-, 2-, 3-, 4-, 5-, 6- or 7-) indolinyloxy group, a 1- (4-trifluoromethoxybenzyl) - 2-oxo (3-, 4-, 5-, 6- or 7-) indoliniloxy, a 1- (4-trifluoromethylbenzyl) - (2-, 3-, 4-, 5-, 6- or 7-) group indolinyloxy, a 1- (4-chlorobenzyl) - (2-, 3-, 4-, 5-, 6- or 7-) indolinyloxy group, a 3- (4-methylbenzyl) - (1-, 2-, 4-, 5-, 6- or 7-) indolinyloxy, a 4- (3,4-dimethylbenzyl) - (1-, 2-, 3-, 5-, 6- or 7-) indolinyloxy group, a group 2 - (2, 4, 6-trimethylbenzyl) - (1-, 3-, 4-, 5-, 6- or 7-) indolinyloxy, a 5- (4-methoxybenzyl) - (1-, 2-, 3) group -, 4-, 6- or 7-) indolinyloxy, a 6- (3,4-dimethoxybenzyl) - (1-, 2-, 3-, 4-, 5- or 7-) indolinyloxy group, a group 7- (3,4,5-trimethoxybenzyl) - (1-, 2-, 3-, 4-, 5-6-6) indolinyloxy, a 1- (4-fluorobenzyl) - (2-, 3-, 4-, 5-, 6- or 7-) indolinyloxy, a 1- (3,4-dichlorobenzyl) - (2-, 3-, 4-, 5-, 6- or 7-) indolinyloxy group, a group 1- (2 , 4, 6-trifluorobenzyl) - (2-, 3-, 4-, 5-, 6- or 7-) indolinyloxy, a 2-oxo- (l-, 3-, 4-, 5-, 6-, or 7-) indolinyloxy group, a 1,3-dibenzyl group (2-, 4-, 5-, 6- or 7-) indolinyloxy, a 1,5,6-tribenzyl (1-, 2-, 3-, 4- or 7-) indolinyloxy group, a 2,3-dioxo group (1-, 4-, 5-6) - or 7-) indolinyloxy or the like. A pyrrolyl group [wherein, in the pyrrole ring, at least one selected from the group consisting of a C1-C6 alkyl group and a C1-C6 alkyl group phenyl (wherein, in the phenyl ring, at least one selected from the group which consists of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes a pyrrolyl group [wherein, in the pyrrole ring, 1 to 3 substituents selected from the group consisting of a Cl-Cß alkyl group as described above and a Cl-Cβ phenyl alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the of alkyl as described above (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halo Oxygen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted can be substituted), for example, a (1-, 2- or 3-) pyrrolyl group, a 1- (4-trifluoromethoxybenzyl) - ( 2- or 3-) pyrrolyl, a 1- (4-trifluoromethylbenzyl) - (2- or 3-) pyrrolyl group, a 1- (4-chlorobenzyl) - (2- or 3-) pyrrolyl group, a group l- (4-methoxybenzyl) - (2- or 3-) pyrrolyl, a 1- (4-methylbenzyl) - (2- or 3-) pyrrolyl group, a 1- (3,4-dimethoxybenzyl) - (2-) group 3-) pyrrolyl, a 1- (2,4,6-trimethoxybenzyl) - (2- or 3-) pyrrolyl group, a 1- (3,4-dimethylbenzyl) - (2- or 3-) pyrrolyl group, a Group 1- (2,4,6-trimethylbenzyl) - (2- or 3-pyrrolyl), a 1- (2,4,6-trifluorobenzyl) - (2- or 3-pyrrolyl) group 1- ( 2,6-dichlorobenzyl) - (2- or 3-pyrrolyl), a 1-benzyl- (2- or 3-pyrrolyl) group, a 1,2-dibenzyl- (3-, 4- or 5-) pyrrolyl group , a 1, 2, 4-tribenyl- (3- or 5-) pyrrolyl group, a 2- (3-chloro-4-trifluoromethoxybenzyl) - (1 group -, 3-, 4- or 5-) pyrrolyl, a l-methyl- (2- or 3-) pyrrolyl group, a 1-ethyl- (2- or 3-) pyrrolyl group, a 1-n-propyl group - (2- or 3-) pyrrolyl, a 1-n-butyl- (2- or 3-) pyrrolyl group, a group 1-n-pentyl- (2- or 3-pyrrolyl, l-hexyl- (2- or 3-pyrrolyl, a 1,3-dimethyl- (2-, 4- or -5) pyrrolyl group, a group 1,3,4-trimethyl- (2- or 5-) pyrrolyl, a group l-benzyl-3-methyl- (2-, 4- or 5-) pyrrolyl or the like. A phenylthio group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) includes a phenylthio group unsubstituted or having 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen as defined above, examples of which include a phenylthio group, a 2-fluorophenylthio group, a 3-fluorophenylthio group, a 4-fluorophenylthio group, a 2-chlorophenylthio group, a 3-group chlorophenylthio, a 4-chlorophenylthio group, a 2-bromophenylthio group, a 3-bromophenylthio group, a 4-bromophenyl group, a 2-iodophenylthio group, a 3-iodophenylthio group, a 4-iodophenylthio group, a 2, 3 group ~ difluorophenyl thio, a 3,4-difluorophenyl group, a 3, 5-difluorophenylthio group, a 2,4-difluorophenylthio group, a 2,6-difluorophenylthio group, a 2,3-dichlorophenylthio group, a 3,4-dichlorophenylthio group, a 3, 5-dichlorophenylthio group, a 2-dichlorophenylthio group, a 2,6-dichlorophenylthio group, a 3, 4, 5-trifluorophenylthio group, a 3, 4, 5-trichlorophenylthio group, a 2,4,6 group -trifluorophenylthio, a 2, 4,6-trichlorophenylthio group, a 2-fluoro-4-bromophenylthio group, a 4-chloro-3-fluorophenylthio group, a 2, 3, 4-trichlorophenylthio group, a 2,3,4-group , 5,6-pentafluorophenylthio, a 2, 4, 6-trimethylphenylthio group, a 4-n-butylphenylthio group, a 2,4-dimethylphenylthio group, a 2, 3-dimethylphenylthio group, a 2, 6-dimethylphenylthio group, a group 3, 5-dimethylphenylthio, a 2, 5-dimethylphenylthio group, a 3, 5-ditrifluoromethylphenylthio group, a 4-n-butoxyphenylthio group, a 2,4-dimethoxyphenylthio group, a 2,3-dimethoxyphenylthio group, a 2 group , 6-dimethoxyphenylthio, a 3, 5-dimethoxyphenylthio group, a 2, 5-dime group Toxyphenylthio, a 2, 4,6-trimethoxyphenylthio group, a 3,5-ditrifluoromethoxyphenylthio group, a 3-chloro-4-methoxyphenylthio group, a 2-chloro-4-trifluoromethoxyphenylthio group, a 3-methyl-4-fluorophenylthio group, a 4-bromo-3-trifluoromethylphenylthio group, a 2-methylphenylthio group, a 3-methylphenylthio group, a 4-methylphenylthio group, a 2-methyl-3-chlorophenylthio group, a 3-methyl-4-chlorophenylthio group, a group 2-Chloro-4-methylphenylthio, a 2-methyl-3-fluorophenylthio group, a 2-trifluoromethylphenylthio group, a 3-trifluoromethylphenylthio group, a 4-trifluoromethylphenylthio group, a 2-pentafluoroethylphenylthio group, a 3-pentafluoroethylphenylthio group, a group 4-pentafluoroethylphenylthio, a 2-isopropylphenylthio group, a 3-isopropylphenylthio group, a 4-isopropylphenylthio group, a 2-tert-butylphenylthio group, a 3-tert-butylphenylthio group, a 4-tert-butylphenylthio group, a 2- group sec-butylphenylthio, a 3-sec-butylphenylthio group, a 4-sec-butylphenylthio group, a 2-n-hepafluoropropylphenylthio group, a 3-n group heptafluoropropylphenylthio, a 4-n-heptafluoropropylphenylthio group, a 4-pentylphenylthio group, a 4-hexylphenylthio group, a 2-methoxyphenylthio group, a 3-methoxyphenylthio group, a 4-methoxyphenylthio group, a 3-chloro-2-methoxyphenylthio group , a 2-fluoro-3-methoxyphenylthio group, a 2-fluoro-4-methoxyphenylthio group, a 2,3,4-trifluorophenylthio group, a 2-trifluoromethoxyphenylthio group, a 3-trifluoromethoxyphenylthio group, a 4-trifluoromethoxyphenylthio group, a 3-fluoro-2-trifluoromethoxyphenylthio group, a 2-fluoro-3-trifluoromethoxyphenylthio group, a 3-fluoro-4-trifluoromethoxyphenylthio group, a 3-chloro-2-trifluoromethoxyphenylthio group, a 2-chloro-3 group -trifluoromethoxy-phenylthio, a 3-chloro-4-trifluoromethoxyphenylthio group, a 2-pentafluoroethoxyphenylthio group, a 3-pentafluoroethoxyphenylthio groupGroup, a 4-pentafluoroetoxifeniltio group, a 3-chloro-2-pentafluoroetoxifeniltio group, a 2-chloro-3-pentafluoroetoxifeniltio group, a 3-chloro-4-pentafluoroetoxifeniltio group, a 2-isopropoxifeniltio group, a 3-isopropoxifeniltio a 4-isopropoxyphenylthio group, a 2-tert-butoxyphenylthio group, a 3-tert-butoxyphenylthio group, a 4-tert-butoxyphenylthio group, a 2-sec-butoxyphenylthio group, a 3-sec-butoxyphenylthio group, a 4-sec group -butoxifeniltio, 2-n-heptafluoropropoxifeniltio heptafluoropropoxifeniltío 3-n-heptafluoropropoxifeniltio 4-n-group, a group, a group, a 4-n-pentoxifeniltio group, a 4-n-hexiloxifeniltio or similar. A piperazinyl group [wherein, in the piperazine ring, at least one selected from the group consisting of a C1-C3 alkyl phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted), a phenyl group [wherein, in the phenyl ring, at least one selected from the group which consists of a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a substituted C1-C6 alkoxy group or not substituted by halogen can be substituted), a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted] and a C2- alkenyl group C6 phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen may be substituted] may be substituted] includes, in addition to a piperazinyl group as described above [wherein, in the piperazinyl ring, at least one Cl-Cß phenyl alkyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a piperazinyl group [in where, in the piperazine ring, 1 to 3 substituents selected from the group consisting of a Cl-Cβ phenyl alkyl group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group upo consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted), a phenyl group [wherein, in the phenyl ring , 1 to 5 preferably 1 to 3 substituents selected from the group consisting of a phenoxy group as described above (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom , a substituted or unsubstituted C1-C6 alkyl group with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted), a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted by halogen can be substituted] and a C2-C6 alkenyl group phenyl having a straight or branched alkenyl group containing 2 to 6 carbon atoms in the alkenyl portion and having 1 to 3 double bonds as described later, and includes both trans and cis forms [wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen and a C1-C6 alkoxy group substituted or unsubstituted by halogen can be substituted] can be substituted], for example, a 4- (3- (4-trifluoromethylphenyl) -2-propenyl) - (1-, 2- or 3-) piperazinyl group, a 4- (4-methoxyphenyl) - (1-, 2-) group or 3-) piperazinyl, a 4- (3,4-dimethylphenyl) - (1-, 2- or 3-) piperazinyl group, a 4- (4-fluorophenyl) - (1-, 2- or 3-) group piperazinyl, a 4- (4-trifluoromethylphenyl) - (1-, 2- or 3-) piperazinyl group, a 4- (4-methylphenyl) - (1-, 2- or 3-) piperazinyl group, a 4- group (3,4-dichlorophenyl) - (1-, 2- or 3-) piperazinyl, a 4- (4-trifluoromethoxyphenyl) - (1-, 2- or 3-) piperazinyl group, a 4- (4- ( 4-chlorophenoxy) phenyl) - (1-, 2- or 3-) piperazinyl or the like. A C 1 -C 6 alkyl naphthyl group includes a naphthylalkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl portion, for example, a ((1- or 2) naphthyl) methyl group, a group 1 - ((1- or 2-) naphthyl) ethyl, a group 2 - ((1-) 2- naphthyl) ethyl, a group 3 - ((1-) 2-) naphthyl) propyl, a group 2 - ((1-) 2- (naphthyl) propyl, a 4 - ((1-) 2- naphthyl) -butyl group, a 5 - ((1-) 2- naphthyl) pentyl group, a 4- ( (I- or 2-) naphthyl) pentyl, a 6 - ((1-) 2- naphthyl) hexyl group, a 2-methyl-3- ((1- or 2-) naphthyl) propyl group, a group 1 , l-dimethyl-2- ((1- or 2-) naphthyl) ethyl or the like. A piperazinyl group [wherein, in the piperazine ring, at least one selected from the group consisting of a C1-C6 alkoxycarbonyl group, a C1-C6 alkyl furyl group [wherein, in the furan ring, at least one phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted], a C 1 -C 6 alkyl pyridyl group [wherein, in the pyridine ring, at least one selected from the group consisting of a furyl group and a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), an alkyl Cl group can be substituted -Cß benzothienil or (wherein, in the benzothiophene ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can to be substituted), a C2-C6 alkenyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C3 alkyl group substituted or unsubstituted with halogen and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen can be substituted), a Cl-Cβ alkyl benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], a C2-C6 alkenyl benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consists of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted], a Cl-Cβ thiazolyl alkyl group [wherein, in the thiazole ring, at least one phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted by halogen can be substituted), a Cl-Cβ phenoxy alkyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-alkyl group) Cß substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted), an alkyl Cl-Cβ indolyl group (wherein, in the indole ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) and a Cl-Cβ phenyl alkyl group (wherein, on the phenyl ring, at least one selected from the group consisting of benzofuryl group, a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes, in addition to a piperazinyl group as described above [wherein, in the piperazine ring, at least a C1-C3 alkyl phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a benzofuryl group, a halogen atom, a C1-C3 alkyl group substituted or unsubstituted by halogen, and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen can be substituted) can be substituted], a piperazinyl group which can be substituted in the piperazine ring by 1 to 3 substituents selected from the group consisting of a Cl-Cß alkoxycarbonyl group as described later, a Cl-Cß furyl alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl moiety as described later [wherein, in the furan ring, 1 to 3 phenyl groups (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted Cl-Cβ alkyl group or unsubstituted with halogen can be substituted) can be substituted], a Cl-Cβ pyridyl alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the n of alkyl as described later [wherein, in the pyridine ring, 1 to 3 substituents selected from the group consisting of a furyl group and a phenyl group (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted], an alkyl group Cl-Cβ benzothienyl having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl moiety as described later (wherein, in the benzothiophene ring, 1 to 3 substituents selected from the group consisting of halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a C2-C6 alkenyl group which has a straight or branched alkenyl group containing 2 to 6 carbon atoms in the alkenyl portion and having 1 to 3 double bonds as described later, and includes both trans and cis forms (wherein, in the ring phenyl, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted ), a Cl-Cβ benzofuryl alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl portion as described later [wherein, in the benzofuran ring, 1 to 3 substituents selected from a group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted], a group C2-C6 alkenyl benzofuryl having a straight or branched alkenyl group having a straight or branched alkenyl group containing 2 to 6 carbon atoms and having 1 to 3 double bonds in the alkenyl portion as described later, and includes both trans and cis forms [wherein, in the benzofuran ring, 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and an alkoxy Cl- group C C substituted or unsubstituted with halogen can be substituted], a Cl-Cβ thiazolyl alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl portion as described later [wherein, in the thiazole ring, 1 or 2 phenyl groups (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted], a Cl-Cβ phenoxy alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl moiety as described later (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), an alkyl Cl-Cβ indolyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl portion as described later (wherein, in the indole ring, 1 to 3 substituents selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a substituted or unsubstituted Cl-Cβ alkoxy group halogen can be substituted) and a Cl-Cβ phenyl alkyl group as described later (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a benzofuryl ring, a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), for example, a 4-tert-butoxycarbonyl group - (1-, 2- or 3-) piperazinyl, a group 4- (4- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) benzyl) - (1-, 2 - or 3-) piperazinyl, a group 4- (3- ((2- or 3-) furyl) pyridyl) methyl) - (1-, 2- or 3-) piperazinyl, a group 4- (2- (4 -trifluoromethoxyphenyl) pyridylmethyl) - (1-, 2- or 3-) piperazinyl, a 4- (2- (3-chloro-4-fluorophenyl) pyridylmethyl) - (1-, 2- or 3-) piperazinyl group, a 4- (5-trifluoromethyl (2-, 3-, 4-, 6- or 7-) benzofurylmethyl) - (1-, 2- or 3-) piperazinyl, a 4- (6-trifluoromethyl- (2- , 3-, 4-, 5- or 7-) benzofurylmethyl) - (1-, 2- or 3-) piperazinyl, a group 4- (5-chloro (2-, 3-, 4-, 6- or 7 -) benzothienylmethyl) - (1-, 2-, or 3-) piperazinyl, a 4- (6-chloro (2-, 3-, 4-, 5- or 7-) benzofurylmethyl) - (1-, 2) group - or 3-) piperazinyl, a 4- (5-trifluoromethoxy (2-, 3-, 4-, 6- or 7-) benzofurylmethyl) - (1-, 2- or 3-) piperazinyl group, a group 4- ( 3- (4-trifluoromethylphenyl) -2-propenyl) - (1-, 2- or 3-) piperazinyl, a 4- (3- (3,4-dichlorophenyl) -2-propenyl) - (1-, 2) group - or 3-) piperazinyl, 4- (3- (4-chlorophenyl) -2-propenyl) - (1-, 2- or 3-) piperazinyl, a 4- (3- (6-trifluoromethyl (2-, 3-, 4-, 5- or 7-) benzofuryl) -2-propenyl) - (1-, 2- or 3-) piperazinyl, a group 4- (3- (5-chloro (2-, 3-, 4-, 5- or 7-) benzofuryl)) -2-propenyl) - (1-, 2- or 3-) piperazinyl, a group 4- (5-chloro (2-, 3-, 4-, 6- or 7-) benzofurylmethyl) - (1-, 2- or 3-) piperazinyl, a 4- (2- (4-trifluoromethylphenyl) - (4- or 5-) thiazolylmethyl) - (1-, 2- or 3- -) piperazinyl, a 4- (2- (4-trifluoromethoxyphenoxy) ethyl) - (1-, 2- or 3-) piperazinyl group, a 4- (3- (4-trifluoromethoxyphenyl) -2-propenyl) - ( 1-, 2- or 3-) piperazinyl, a 4- (5-trifluoromethoxy (1-, 2-, 3-, 4-, 6- or 7-) indolylmethyl group) - (1-, 2- or 3-) piperazinyl, a 4- (2- (4-chlorophenyl) - (3-, 4- or 5-) furylmethyl) - (1-) group, 2- or 3-) piperazinyl, a 4- (2- (2-chloro-5-trifluoromethylphenyl) - (3-, 4- or 5-) furylmethyl) - (1-, 2- or 3-) piperazinyl group or similar. A C 1 -C 6 alkyl benzothienyl group (wherein, in the benzothiophene ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen and a substituted Cl-Cβ alkyl group or unsubstituted with halogen can be substituted) includes a Cl-Cβ benzothienyl alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl moiety (wherein, in the benzothiophene ring, 1 to 3 substituents selected from the group consisting of a Cl-Cß alkoxy group substituted or unsubstituted by halogen and a Cl-Cß alkyl group substituted or unsubstituted by halogen can be substituted), for example, a group ((2-, 3-, 4-, 5-, 6- or 7-) benzothienyl) methyl, a group l - ((2-, 3-, 4-, 5-, 6- or 7-) benzothienyl) ethyl, a group 2- (( 2-, 3-, 4-, 5-, 6- or 7-) benzothienyl) ethyl, a 3- ((2-, 3-, 4-, 5-, 6- or 7-) benzothienyl) propyl group, a group 2- ((2-, 3- , 4-, 5-, 6- or 7-) benzothienyl) propyl, a group 4- ((2-, 3-, 4-, 5-, 6- or 7-) benzothienyl) butyl, a group 5- ( (2-, 3-, 4-, 5-, 6- or 7-) benzothienyl) pentyl, a 4- ((2-, 3-, 4-, 5-, 6- or 7-) benzothienyl) pentyl group , a group 6- ((2-, 3-, 4-, 5-, 6- or 7-) benzothienyl) hexyl, a group 2-methyl-3- ((2-, 3-, 4-, 5- 6- or 7-) benzothienyl) propyl, a 1, l-dimethyl-2- ((2-, 3-, 4-, 5-, 6- or 7-) benzothienyl) ethyl group, a 5-chloro- (2-, 3-, 4-, ß- or 7-) benzothienylmethyl, a 5-methyl- (2-, 3-, 4-, 6- or 7-) benzothienylmethyl group, a 5-methoxy- (2 -, 3-, 4-, ß- or 7-) benzothienylmethyl, a 5-trifluoromethyl- (2-, 3-, 4-, 6- or 7-) benzothienylmethyl group, a 5-trifluoromethoxy- (2-, 3-, 4-, 6- or 7-) benzothienylmethyl, a 5,6-dichloro- (2-, 3-, 4- or 7-) benzothienylmethyl group, a 4, 5, ß-trifluoro- (2- , 3- or 7-) benzothienylmethyl, a 5-chloro-6-trifluoromethoxy- (2-, 3-, 4- or 7-) benzothienylmethyl group, a 2, 5-dimethyl- (3-, 4-, 6- - or 7-) benzothienylmethyl, a 2, 5, 6-trimethyl- (3-, 4-, 6- or 7-) benzothienylmethyl group or the like. A Cl-Cβ thiazolyl alkyl group [wherein, in the thiazole ring, at least one phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group) substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes a Cl-Cβ thiazolyl alkyl group a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl portion [wherein, in the thiazole ring, 1 to 2 phenyl groups as described above (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom , a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted, for example, a group ((2-, 4- or 5- thiazolyl) methyl, a graph upo l - ((2-, 4- or 5-) thiazolyl) ethyl, a group 2- ((2-, 4- or 5-) thiazolyl) ethyl, a group 3- ((2-, 4- or 5) -) thiazolyl) propyl, a 2- ((2-, 4- or 5-) thiazolyl) propyl group, a 4- ((2-, 4- or 5-) thiazolyl) butyl group, a group 5- (( 2-, 4- or 5-) thiazolyl) pentyl, a 4- ((2-, 4- or 5-) thiazolyl) pentyl group, a 6- ((2-, 4- or 5-) thiazolyl) hexyl group , a 2-methyl-3- ((2-, 4- or 5-) thiazolyl) propyl group, a 1, 1-dimethyl-2- ((2-, 4- or 5-) thiazolyl) ethyl group, a 2- (4-trifluoromethylphenyl) - (4- or 5-) thiazolylmethyl group, a 2- (4-trifluoromethylphenyl) - (4- or 5-) thiazolylmethyl group, a 2- (4-trifluoromethoxyphenyl) - (4-) group or 5-) thiazolylmethyl, a 4- (3-methylphenyl) - (2- or 5-) thiazolylmethyl group, a 5- (2-methoxyphenyl) - (2- or 5-) thiazolylmethyl group, a group 4- (4 -chlorophenyl) - (2- or 5-) thiazolylmethyl, a 2- (2-, 4-dimethylphenyl) - (4- or 5-) thiazolylmethyl group, a 2- (2,4-, 6-trimethylphenyl) - (4- or 5-) thiazolylmethyl group, a 2- group (3, 4-dimethoxyphenyl) - (4- or 5-) thiazolylmethyl, a 2- (3,4-trimethoxyphenyl) - (4- or 5-) thiazolylmethyl group, a 2- (3-chloro-4) group -trifluoromethylphenyl) - (4- or 5-) thiazolylmethyl, a 4- (3,4-dichlorophenyl) - (2- or 5-) thiazolylmethyl group, a 2- (3,4-, 6-trifluorophenyl) - (4-trifluorophenyl) group - or 5-) thiazolylmethyl, a 2, 4-diphenyl (4- or 5-) thiazolylmethyl group or the like. An indolyl C1-C6 alkyl group (wherein, in the indole ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a substituted C1-C6 alkoxy group or unsubstituted with halogen can be substituted) includes a C 1 -C 6 indolyl alkyl group having a straight or branched alkyl group containing 1 to β carbon atoms in the alkyl moiety (wherein, in the indole ring, 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), for example, a group ((1 -, 2-, 3-, 4-, 5-, 6-or 7-) indolyl) methyl, a group 1 - ((1-, 2-, 3-, 4-, 5-, 6- or 7- ) indolyl) ethyl, a group 2 - ((l-, 2-, 3-, 4-, 5-, 6- or 7-) indolyl) ethyl, a group 3 - ((1-, 2-, 3- , 4-, 5-, 6- or 7-) indolyl) propyl, a group 2 - ((1-, 2-, 3-, 4-, 5-, 6- or 7-) indolyl) propyl, a group 4 - ((l-, 2-, 3-, 4-, 5-, 6- or 7-) indolyl) butyl, a group 5 - ((l-, 2-, 3-, 4-, 5-, 6- or 7-) indolyl) pentyl, a group 4- (l-, 2-, 3-, 4-, 5- , 6- or 7-) indolyl) pentyl, a group 6 - ((l-, 2-, 3-, 4-, 5-, 6- or 7-) indolyl) hexyl, a 2-methyl-3- group ((1-, 2-, 3-, 4-, 5-, 6- or 7-) indolyl) propyl, a group 1, l-dimethyl-2- ((1-, 2-, 3-, 4- , 5-, 6- or 7-) indolyl) ethyl, a 2-trifluoromethyl- (1-, 3-, 4-, 5-, 6- or 7-) indolylmethyl group, a 5-trifluoromethyl- (1-) group , 2-, 3-, 4-, 6- or 7-) indolylmethyl, a 2-trifluoromethoxy- (1-, 3-, 4-, 5-, 6- or 7-) indolylmethyl group, a 4-methyl group - (l-, 2-, 3-, 5-, 6- or 7-) indolylmethyl, a 5-methoxy- (1-, 2-, 3-, 4-, 6- or 7-) indolylmethyl group, a group 4-chloro- (l-, 2-, 3-, 5-, 6- or 7-) indolylmethyl, a group 2, 4-dimethyl- (1-, 3-, 5-, 6- or 7-) indolylmethyl, a 2, 4, 6-trimethyl- (1-, 3-, 5- or 7-) indolylmethyl group, a 3, 4-dimethoxy- (1-, 2-, 5-, 6- or 7-) group indolylmethyl, a 3, 4, 5-trimethoxy- (1-, 2-, 6- or 7-) indolylmethyl group, a 3-chloro-4-trifluoromethyl- (1-, 2-, 5-, 6- or 7-) group ) indolylmethyl, a 3, 4-dichloro- (1-, 2-, 5-, 6- or 7-) indolylmethyl group, a group 3, 4, 6-trifluoro- (1-, 2-, 5- or 7) -) indolylmethyl, a 5-trifluoromethoxy- (1-, 2-, 3-, 4-, 6- or 7-) indolylmethyl group, a 5-trifluoromethoxy-6-chloro- (1-, 2-, 3-) group , 4- or 7-) indolylmethyl, a 1,3-dimethyl-5-fluoro- (2-, 4-, 6- or 7-) indolylmethyl group or the like. A C 1 -C 6 alkyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a benzofuryl group, a halogen atom, a substituted or unsubstituted C 1 -C 6 alkyl group, and an alkoxy group C 1 -C 6 substituted or unsubstituted with halogen can be substituted) includes, in addition to a C 1 -C 6 alkyl phenyl group as described above (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom , a C1-C6 alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted), a Cl-Cß phenyl alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl portion (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a benzofuryl group, a halogen atom, a Cl-Cß alkyl group either unsubstituted or substituted by halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), for example, a group 4- ((2-, 3-, 4-, 5-, ß- or 7-) benzofuryl) benzyl, a group 2- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) benzyl, a 3- ((2-, 3-, 4-, 5-, ß- or 7-) benzofuryl) benzyl group, a 3, 4-di ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) benzyl, a 2, 4, 6-tri ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl group) benzyl, a 3-chloro-4- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) benzyl group or the like. A C 1 -C 6 alkyl group phenyl [wherein, in the phenyl group, at least one phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group) substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes a Cl-Cβ phenyl alkyl group having a straight or branched alkyl group containing 1 to ß atoms of carbon in the alkyl portion [wherein, in the phenyl ring, 1 to 3 phenyl groups as described above (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of one atom of halogen, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), for example, a 4-phenylbenzyl group, a group 3 fenilbenc ilo, a 2-phenylbenzyl group, a 2,4-diphenylbenzyl group, a 2,4,6-triphenylbenyl group, a 4- (4-trifluoromethoxyphenyl) benzyl group, a 2- (3-trifluoromethylphenyl) benzyl group, a group 4- (2-fluorophenyl) benzyl, a 3- (4-chlorophenyl) benzyl group, a 4- (4-methoxyphenyl) benzyl group, a 3- (4-ethylphenyl) benzyl group, a 2- (3, 4) group -methoxyphenyl) benzyl, a 4- (3,4-dimethylphenyl) benzyl group, a 3- (3,4,6-trimethoxyphenyl) benzyl group, a 2- (2,4,5-trimethylphenyl) benzyl group, a group 4- (3,4-dichlorophenyl) benzyl, a 2- (2,4-, 6-trifluorophenyl) benzyl group, a 4- (3-chloro-4-trifluoromethoxyphenyl) benzyl group, a 2- (4- (2) group - fluorophenyl) phenyl) ethyl, a 3- (2- (3,4-dimethoxyphenyl) phenyl) propyl group, a 4- (2- (2,4,5-trimethylphenyl) phenyl) butyl group, a group 5- ( 4- (3-chloro-4-trifluoromethoxyphenyl) phenyl) pentyl, a 6- (2- (3-trifluoromethylphenyl) phenyl) hexyl group, a l- (4- (4-trifluoromethoxyphenyl) phenyl) ethyl group or the like. A phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C 1 -C 6 alkyl group with halogen and a substituted or unsubstituted C 1 -C 6 alkoxy group halogen is substituted) includes is a phenoxy group having 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen as defined above, examples of which include a 2-fluorophenoxy group, a 3-fluorophenoxy group, a 4-fluorophenoxy group, a 2-chlorophenoxy group, a 3-chlorophenoxy group, a 4- group chlorophenoxy, a 2-bromophenoxy group, a 3-bromophenoxy group, a 4-bromophenoxy group, a 2-iodophenoxy group, a 3-iodophenoxy group, a 4-iodophenoxy group, a 2,3-difluorophenoxy group, a group 3, 4-difluorophenoxy, a 3, 5-difluorophenoxy group, a Group 2, 4-difluorophenoxy, a 2, 6-difluorophenoxy group, a 2,3-dichlorophenoxy group, a 3,4-dichlorophenoxy group, a 3,5-dichlorophenoxy group, a 2,4-dichlorophenoxy group, a 2 group , 6-dichlorophenoxy, a 3, 4, 5-trifluorophenoxy group, a 3, 4, 5-trichlorophenoxy group, a 2, 4,6-trifluorophenoxy group, a 2, 4,6-trichlorophenoxy group, a 2-fluoro group -4-bromophenoxy, a 4-chloro-3-fluorophenoxy group, a 2,3,4-trichlorophenoxy group, a 3, 4, 5-trifluorophenoxy group, a 2, 3, 4, 5, 6-pentafluorophenoxy group, a Group 2, 4, 6-trimethylphenoxy, a 4-n-butylphenoxy group, a 2,4-dimethylphenoxy group, a 2,3-dimethylphenoxy group, a 2 group, 6-dimethylphenoxy, a 3, 5-dimethylphenoxy group, a 2,5-dimethyl phenoxy group, a 3, 5-ditrifluoromethylphenoxy group, a 4-n-butoxyphenoxy group, a 2,4-dimethoxyphenoxy group, a group 2, 3-dimethoxyphenoxy, a 2, 6-dimethoxyphenoxy group, a 3,5-dimethoxyphenoxy group, a 2,5-dimethoxyphenoxy group, a 2, 4,6-trimethoxyphenoxy group, a 3, 5-ditrifluoromethoxyphenoxy group, a 3- group chloro-4-methoxyphenoxy, a 2-chloro-4-trifluoromethoxyphenoxy group, a 3-methyl-4-fluorophenoxy group, a 4-bromo-3-trifluoromethylphenoxy group, a 2-methylphenoxy group, a 3-ethylphenoxy group, a group 4-methylphenoxy, a 2-methyl-3-chlorophenoxy group, a 3-methyl-4-chlorophenoxy group, a 2-chloro-4-methylphenoxy group, a 2-methyl-3-fluorophenoxy group, a 2-trifluoromethylphenoxy group, a 3-trifluoromethylphenoxy group, a 4-trifluoromethylphenoxy group, a 2-pentafluoroethylphenoxy group, a 3-pentafluoroethylphenoxy group, a 4-pentaf luoroethyl-enoxy group, a 2-isopropyl-enoxy group, a 3-isopropyl-enoxy group, a 4-group isopropi lf enoxi, a 2-tert-butyl-enoxy group, a 3-tert-butyl-enoxy group, a 4-tert-butyl-enoxy group, a 2-sec-butylphenoxy group, a 3-sec-butylphenoxy group, a 4- group sec-butílf enoxi, a group 2-n-heptaf luoropropilf enoxi, a group 3-n-heptaf luoropropilf enoxi, a group -n-heptaf luoropropilf enoxi, a group 4-n-pentyl-enoxi, a group 4-n-hexylf enoxi, a 2-methoxy group, a 3-methoxy group, a 4-methoxy group, a 3-chloro-2-methoxy group, a 2-fluoro-3-methoxyphenoxy group, a 2-fluoro group 4-methoxyphenoxy, a 2, 6-dimethoxy-enoxi group, a 2, 3, 4-trif luorofenoxi group, a 2, 4, 6-trif luorofenoxi group, a 2-trif luoromethoxyif enoxi group, a 3-trif group luoromethoxif enoxi, a group 4-trif luoromethoxif enoxi, a group 3-fluoro-2-trif luoromethoxifenoxi, a group 2-fluoro-3-trif luoromethoxifenoxi, a group 3-f luoro-4-trif luoromethoxif enoxi, a group 3-chloro-2-t rif luoromethoxif enoxi, a group 2-chloro-3-trif luoromethoxif enoxi, a group 3 -chloro-4-trifluoromethoxyphenoxy, a 2-pentaf luoroethoxy-enoxi group, a 3-pentaf luoroethoxy-enoxi group, a 4-pentaf luoroethoxy-enoxi group, a 3-chloro-2-pentaf-luoroethoxy-enoxi group, a 2-chloro-3 group -pentaf luoroethoxy enoxi, a 3-chloro-4-pentaf luoroethoxy-enoxi group, a 2-isopropoxy-enoxi group, a 3-isopropoxy-enoxi group, a 4-isopropoxy-enoxi group, a 2-tert-butoxy-enoxi group, a 3-group -tert-butoxif enoxí, a group 4-tert-butoxifenoxi, a group 2-sec-butoxifenoxi, a group 3-sec-butoxifenoxi, a group 4- sec-butoxifenoxi, a group 2-n-heptafluoropropoxifenoxi, a group 3- n-heptafluoropropoxyphenoxy, a 4-n-heptafluoropropoxyphenoxy group, a 4-n-pentoxyphenoxy group, a 4-n-hexyloxyphenoxy group or the like. A C1-C6 alkyl phenyl group [wherein, on the phenyl ring, at least one phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group) substituted or unsubstituted with halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen is substituted) is substituted] includes a C 1 -C 6 alkyl group phenyl having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl portion [wherein, on the phenyl ring, 1 to 3 phenoxy groups as described above (wherein, on the phenyl ring, 1 to 3 substituents selected from the group consisting of a halogen atom, an alkyl group C1 -C6 substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen are substituted) are substituted], for example, a 4- (4-trifluoromethoxyphenyl) benzyl group, a 2, 4-di group ( 4-trifluoromethoxyphenyl) benzyl , a 2- (3-trifluoromethylphenoxy) benzyl group, a 4- (2-fluorophenoxy) benzyl group, a 2, 4,6-tri (2-fluorophenoxy) benzyl group, a 3- (4-chlorophenoxy) benzyl group, a 4- (4-methoxyphenoxy) benzyl group, a 3- (4-methylphenoxy) benzyl group, a 2- (3,4-dimethoxyphenoxy) benzyl group, a 4- (3, -dimethylphenoxy) benzyl group, a 3- (3,4,6-trimethoxyphenoxy) benzyl group, a 2- (2,4,5-trimethylphenoxy) benzyl group, a 4- (3 group, -dichlorophenoxy) benzyl, a 2- (2,4-, 6-trifluorophenoxy) benzyl group, a 4- (3-chloro-4-trifluoromethoxyphenoxy) benzyl group, a 2- (4- (2-fluorophenoxy) phenyl) ethyl group , a 3- (2- (3,4-dimethoxyphenoxy) phenyl) propyl group, a 4- (2- (2,4,5-trimethylphenoxy) phenyl) butyl group, a 5- (4- (3-chloro) group -4-trifluoromethoxyphenoxy) phenyl) pentyl, a 6- (2- (3-trifluoromethylphenoxy) phenyl) hexyl group, an l- (4- (4-trifluoromethoxyphenoxy) phenyl) ethyl group or the like. A thiazolyl group (wherein, in the thiazole ring, at least one phenyl group can be substituted) includes a thiazolyl group (wherein, in the thiazole ring, 1 or 2 phenyl groups can be substituted), for example, a group (2-, 4- or 5-) thiazolyl, a 2-phenyl- (4- or 5-) thiazolyl group, a 4-phenyl- (2- or 5-) thiazolyl group, a 5-phenyl- (2) group - or 4-) thiazolyl, a 2,5-diphenyl-4-thiazolyl group, a 2,4-diphenyl-5-thiazolyl group, a 4,5-diphenyl-2-thiazolyl group. A Cl-Cβ phenoxy alkyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom , a Cl-Cß alkyl group substituted or unsubstituted by halogen and a Cl-Cß alkoxy group substituted or unsubstituted by halogen can be substituted), a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted by halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) includes, in addition to a Cl-Cβ phenoxy alkyl group as described above (which can be substituted by at least one selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted by halogen and a Cl-Cß alkoxy group substituted or unsubstituted by halogen), a Cl-Cß phenoxy alkyl group having a straight or branched alkyl group containing 1 ha to 6 carbon atoms in the alkyl moiety (wherein, in the phenyl ring, 1 to 3 substituents selected from the group consisting of a phenyl group as described above (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted), a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted), for example, a 4-phenylphenoxymethyl group, a 3-phenylphenoxymethyl group, a 2-phenylphenoxymethyl group , a 2, 4-diphenylphenoxymethyl group, a group 2,4,6-triphenylphenoxymethyl, a 4- (4-trifluoromethoxyphenyl) phenoxymethyl group, or a 2- (3-trifluoromethylphenyl) phenoxymethyl group, a 4- (2-fluorophenyl) phenoxymethyl group, a 3- (4- chlorophenyl) phenoxymethyl, a 4- (4-methoxyphenyl) phenoxymethyl group, a 3- (4-methylphenyl) phenoxymethyl group, a 2- (3,4-methoxyphenyl) phenoxymethyl group, a 4- (3,4-dimethylphenyl) group Phenoxymethyl, a 3- (3,4,6-trimethoxyphenyl) phenoxymethyl group, a 2- (2,4,5-trimethylphenyl) phenoxymethyl group, a 4- (3,4-dichlorophenyl) phenoxymethyl group, a group 2 - (2,4,6-trifluorophenyl) phenoxymethyl, a 4- (α-chloro-4-trifluoromethoxyphenyl) phenoxymethyl group, a 2- (4-phenylphenoxy) ethyl group, a 2- (4- ( 2-fluorophenyl) phenoxy) ethyl, a 3- (2- (3,4-dimethoxyphenyl) phenoxy) propyl group, a 4- (2- (2,4,5-trimethylphenyl) phenoxy) butyl group, a 5- group (4- (3-chloro-4-trifluoromethoxyphenyl) phenoxy) pentyl, a 6- (2- (3-trifluoromethylphenyl) phenoxy) hexyl group, a 2- (4- (4-trifluoromethylphenyl) phenoxy group) ethyl, a 2- (4- (4-trifluoromethoxyphenyl) phenoxy) ethyl group or the like. A piperidyl group [wherein, in the piperidine ring, at least one selected from the group consisting of a phenoxy group (on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group) substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) and a Cl-Cß phenyl alkyl group can be substituted] includes, in addition the piperidyl group described above, a piperidyl group [wherein , in the piperidine ring, at least one phenoxy group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen and an alkoxy group Cl-Cβ substituted or not substituted by halogen can be substituted) can be substituted], a piperidyl group [where, in the piperidine ring, 1 to 3 substituents selected from the group consisting of a phenoxy group as described above (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, an alkyl group Cl-Cβ substituted or unsubstituted with halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen can be substituted) and a C 1 -C 6 alkyl group phenyl can be substituted], for example, a 4-benzyl group (1 -, 2- or 3-) piperidyl, a 3-benzyl- (1-, 2-, 4-, 5- or 6-) piperidyl group, a 2-benzyl- group (1-, 3-, 4-, 5- or β-) piperidyl, a 2, 4-dibenzyl- (1-, 3-, 5- or 6-) piperidyl group, a 2, 3, -tribenzyl- (1-, 5- or 6-) group piperidyl, a 4-phenoxy-3-benzyl- (1-, 2-, 5- or 6-) piperidyl group or the like. A Cl-Cβ benzofuryl alkyl group (wherein, in the benzofuran ring, at least one Cl-Cß alkyl group substituted or unsubstituted with halogen can be substituted) includes a Cl-Cβ benzofuryl alkyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl portion (wherein, in the benzofuran ring, 1 to 3 Cl-Cß alkyl groups substituted or unsubstituted with halogen can be substituted), for example, a group ((2- , 3-, 4-, 5-, 6- or 7-) benzofuryl) methyl, a group l - ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) ethyl, a group 2- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) ethyl, a group 3- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) propyl, a group 2- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) propyl, a group 4- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) butyl, a group 5 - ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) pentyl, a group 4- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) pentyl, a group 6- ((2-, 3-, 4-, 5-, 6- or 7-) ben zofuryl) hexyl, a 2-methyl-3- ((2-, 3-, 4-, 5-, 6- or 7-) benzofuryl) propyl group, a 1, 1-dimethyl-2- ((2- , 3-, 4-, 5-, 6- or 7-) benzofuryl) ethyl, a 2-trifluoromethyl- (3-, 4-, 5-, 6- or 7-) benzofurylmethyl group, a 5-trifluoromethyl- (2-, 3-, 4-, 6- or 7-) benzofurylmethyl, a 4-? T? Ethyl- (2-, 3-, 5-, 6- or 7-) benzofurylmethyl group, a group 2, 4 -dimethyl- (3-, 5-, 6- or 7-) benzofurylmethyl, a 2, 4, 6-trimethyl- (3-, 5- or 7-) benzofurylmethyl group, a 4-trifluoromethyl- (2-, 3-, 5-, 6- or 7-) benzofurylmethyl, a 6-trifluoromethyl- (2-, 3-, 4-, 5- or 7-) benzofurylmethyl group or the like. A C1-C6 alkyl piperidylcarbonyl group [wherein, in the piperidine ring, at least one phenoxy group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group) substituted or unsubstituted with halogen and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes a C 1 -C 6 alkyl piperidylcarbonyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms carbon in the alkyl moiety (wherein, in the piperidine ring 1 to 3 phenoxy groups as described above) (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of one atom of halogen, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) is substituted, for example, a group (4-phenoxy-1-piperi) dilcarbonyl) methyl, a 2- (3-phenoxy-2-piperidylcarbonyl) ethyl group, a 3- (2-phenoxy-3-piperidylcarbonyl) propyl group, a 4- (l-phenoxy-4-piperidylcarbonyl) butyl group, a 5- (4-phenoxy-1-piperidylcarbonyl) pentyl group, a 6- (1-phenoxy-2-piperidylcarbonyl) hexyl group, a 1- (4-trifluoromethoxyphenoxy) -4-piperidylcarbonylmethyl group, a 4- (4-) group trifluoromethoxyphenoxy) -1-piperidylcarbonylmethyl, a 4- (4-trifluoromethylphenoxy) -1-piperidylcarbonylmethyl group, a 4- (3-methoxyphenoxy) -1-piperidylcarbonylmethyl group, a 1- (2-methylphenoxy) -4-piperidylcarbonylmethyl group, a 4- (4-chlorophenoxy) -1-piperidylcarbonylmethyl group, a 4- (3,4-di (trifluoromethoxy) phenoxy) -1-piperidylcarbonylmethyl group, a 4- (2,4-, 6-tri (trifluoromethyl) phenoxy) -1-piperidylcarbonyl ethyl group, a 4- (3) group , 4-dimethylphenoxy) -1-piperidylcarbonylmethyl, a 4- (2,4,6-trimethoxyphenoxy) -4-piperidylcarbonylmethyl group, a 2- (3,4-dichlorophenoxy) -1-piperidylcarbonylmethyl group, a 3- (2-group , 4,6-tribromophenoxy) -1-piperidylcarbonylmethyl, a (1, 2, 6-trifenoxy-4-piperidylcarbonyl) methyl group, a (2,4-diphenoxy-1-piperidylcarbonyl) ethyl group or the like. A C 1 -C 6 alkyl oxazolyl group [wherein, in the oxazole ring, at least one phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group) substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes a C 1 -C 6 alkyl oxazolyl group having a straight or branched alkyl group containing 1 to 6 carbon atoms carbon in the alkyl moiety [wherein, in the oxazole ring, 1 or 2 phenyl groups as described above (wherein, in the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consisting of one atom of halogen, a Cl-Cβ alkyl group substituted or unsubstituted by halogen and a Cl-Cβ alkoxy group substituted or unsubstituted by halogen can be substituted), for example, a group ((2-, 4- or 5-) oxazolyl) methyl, a group l - ((2-, 4- or 5-) oxazolyl) ethyl, a group 2- ((2-, 4- or 5-) oxazolyl) ethyl, a group 3- ((2-, 4- or 5-) oxazolyl) propyl, a 2- ((2-, 4- or 5-) oxazolyl) propyl group, a 4- ((2-, 4- or 5-) oxazolyl) butyl group, a 5- ( (2-, 4- or 5-) oxazolyl) pentyl, a 4- ((2-, 4- or 5-) oxazolyl) pentyl group, a 6- ((2-, 4- or 5-) oxazolyl group) hexyl, a 2-methyl-3 - ((2-, 4- or 5-) oxazolyl) propyl group, a 1, 1-dimethyl-2- ((2-, 4- or 5-) oxazolyl) ethyl group, a 4- (4-trifluoromethoxyphenyl) - (2- or 5-) oxazolylmethyl group, a 4- (4-chlorophenyl) - (2- or 5-) oxazolylmethyl group, a 4- (4-trifluoromethylphenyl) - (2 group - or 5-) oxazolylmethyl, a 4- (4-methylphenyl) - (2- or 5-) oxazolylmethyl group, a 4- (4-methoxyphenyl) - (2- or 5-) oxazolylmethyl group, a 4- ( 2,4-dichlorophenyl) - (2- or 5-) oxazolylmethyl, a 4- (2,4-, 6-trifluorophenyl) - (2- or 5-) oxazolylmethyl group, a 2- (3,4-dimethylphenyl) group - (4- or 5-) oxazolylmethyl, a group 5- (3, 4, 6-trimeti) lphenyl) - (2- or 4-) oxazolylmethyl, a 2- (3,4-dimethoxyphenyl) - (4- or 5-) oxazolylmethyl group, a 4- (2,4-b-trimethoxyphenyl) - (2-) group or 5-) oxazolylmethyl, a 4- (3-chloro-4-trifluoromethoxyphenyl) - (2- or 5-) oxazolylmethyl group, a 2,4-diphenyl-5-oxazolylmethyl group, a 4,5-diphenyl-2 group -oxazolylmethyl, a 2, 5-diphenyl-5-oxazolylmethyl group or the like. An isooxazolyl group [wherein, in the isooxazoline ring, at least one phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or not substituted with halogen and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen can be substituted) can be substituted] includes an isooxazolyl group [wherein, in the isooxazoline ring, 1 or 2 phenyl groups as described above (wherein, in the phenyl ring, up to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cß alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted], eg, a (3-, 4- or 5-) isooxazolyl group, a 3-phenyl- (4- or 5-) isooxazolyl group, a 4-phenyl- (3- or 5-) isooxazolyl group, a 5-phenyl- (3- or 4-) isooxazolyl group, a 3, 4-diphenyl-5-isooxazolyl group, a 3, 5-diphenyl-4-isooxazolyl group, a 4,5-diphenyl-3-isooxazolyl group , a 3- (4-trifluorophenyl) - (4- or 5-) isooxazolyl group, a 4- (4-chlorophenyl) - (3- or 5-) isooxazolyl group, a 3- (4-trifluoromethylphenyl) - ( 4- or 5- isooxazolyl, a 4- (4-methylphenyl) - (3- or 5-) isooxazolyl group, a 3- (4-methoxyphenyl) - (4- or 5-) isooxazolyl group, a 4- (2, 4-) group dichlorophenyl) - (3- or 5-) isooxazolyl, a 3- (2,4-, 6-trifluorophenyl) - (4- or 5-) isooxazolyl group, a 3- (3,4-diphenylmethyl) - (4-) group or 5-) isooxazolyl, a 5- (3,4-trimethylphenyl) - (3- or 4-) isooxazolyl group, a 3- (3,4-dimethoxyphenyl) - (4- or 5-) isooxazolyl group, a 4- (2, 4, ß-trimethoxyphenyl) - (3 or 5) isooxazolyl group, a 3- (3-chloro-4-trifluoromethoxyphenyl) - (4- or 5-) isooxazolyl group or the like. A benzooxazolyl group (wherein, in the benzooxazole ring, at least one halogen atom can be substituted) includes a benzooxazolyl group (wherein, in the benzooxazole ring, 1 to 3 halogen atoms can be substituted), for example , a group (2-, 4-, 5-, 6- or 7-) benzooxazolyl, a 5-chloro- (2-, 4-, 6- or 7-) benzooxazolyl group, a 6-chloro- (2) group -, 4-, 5- or 7-) benzooxazolyl, a 5-fluoro (2-, 4-, 6- or 7-) benzooxazolyl group, a 6-bromo- (2-, 4-, 5- or 7-group) -) benzooxazolyl, a 5-iodo- (2-, 4-, 6- or 7-) benzooxazolyl group, a group 5, β-dichloro- (2-, 4- or 7-) benzooxazolyl, a group 4, 5 , ß-trifluoro- (2- or 7-) benzooxazolyl, a 5-fluoro-6-chloro- (2-, 4- or 7-) benzooxazolyl group or the like. A benzoimidazolyl group [wherein, in the benzoimidazole ring, at least one selected from the group consisting of a halogen atom and a Cl-Cβ phenyl alkyl group (wherein, in the phenyl ring, at least one selected from the group consisting of of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes a benzoimidazolyl group [wherein, in the ring benzoimidazole, 1 to 3 substituents selected from the group consisting of a halogen atom and a Cl-Cβ phenyl alkyl group as described above (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consists of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be subs for example, a (2-, 4-, 5-, 6- or 7-) benzoimidazolyl group, a 1- (4-trifluoromethoxybenzyl) -5,6-dichloro- (2-, 4- or 7-substituted) group. -) benzoimidazolyl, a 5-chloro- (l-, 2-, 4-, 6- or 7-) benzoimidazolyl group, a 6-chloro- (l-, 2-, 4-, 5- or 7-) group benzoimidazolyl, a 5-f luoro- (1-, 2-, 4-, 6- or 7-) benzoimidazolyl group, a 6-bromo- (1 ~, 2-, 4-, 5- or 7-) benzoimidazolyl group , a 5-iodo- (l-, 2-, 4-, ß- or 7-) benzoimidazolyl group, a group 5, β-dichloro- (1-, 2-, 4- or 7-) benzoimidazolyl, a group 4, 5, 6-trifluoro- (1-, 2- or 7-) benzoimidazolyl, a 5-f luoro-6-chloro- (1-, 2-, 4- or 7-) benzoimidazolyl group, a group 1 -benzyl- (2-, 4-, 5-, 6- or 7-) benzoimidazolyl, a group 1- (4-trifluoromethylbenzyl) - (2-, 4-, 5-, 6- or 7-) benzoimidazolyl, a 1- (4-chlorobenzyl) - (2-, 4-, 5-, ß- or 7-) benzoimidazolyl group, a group 1- (3- methylbenzyl) - (2-, 4-, 5-, 6- or 7-) benzoimidazolyl, a 1- (2-methoxybenzyl) - (2-, 4-, 5-, 6- or 7-) benzoimidazolyl group, a Group 1- (3, 4-dimethylbenzyl) - (2-, 4-, 5-, 6- or 7-) benzoimidazolyl, a group l- (2,4,6-trimethylbenzyl) - (2-, 4-, 5-, 6- or 7-) benzoimidazolyl, a 1- (3,4-dimethoxybenzyl) - (2-, 4-, 5-, 6- or 7-) benzoimidazolyl group, a group 1- (2,4, 5-trimethoxybenzyl) - (2-, 4-, 5-, 6- or 7-) benzoimidazolyl, a 1- (3,4-dichlorobenzyl) - (2-, 4-, 5-, 6- or 7- ) benzoimidazolyl, a 1- (2,4,6-trifluorobenzyl) - (2-, 4-, 5-, 6- or 7-) benzoimidazolyl group, a 1- (3-chloro-4-trifluoromethylbenzyl) - (2-, 4-, 5-, 6- or 7-) benzoimidazolyl, a group (1, 5-benzyl- (2-, 4-, 6- or 7-) benzoimidazolyl, a group 1,5,6- tribencyl- (2-, 4- or 7-) benzoimidazolyl, or the like. An imidazolyl group [wherein, on the imidazole ring, at least one group f enyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can to be substituted) is substituted] includes an imidazolyl group [wherein, on the imidazole ring, 1 or 2 phenyl groups as described above (wherein, on the phenyl ring, 1 to 5, preferably 1 to 3 substituents selected from the group consists of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) are substituted], for example, a 2-f-enyl group (4- or 5-) imidazolyl, a 4-f-enyl- (2- or 5-) imidazolyl group, a 2,4-difyl enyl-5-imidazolyl group, a 2,4-diphenyl-5-imidazolyl group, a 4, 5-diphenyl-2-imidazolyl group, a 2- (4-trifluoromethoxy-enyl) - (4- or 5-) imidazolium group lo, a 2- (4-trif luorofenyl) - (4- or 5-) imidazolyl group, a 4- (4-chlorophenyl) - (2- or 5-) imidazolyl group, a 4- (4-trif) group luoromethylphenyl) - (2- or 5-) imidazolyl, a 4- (4-methylf-enyl) -2-imidazolyl group, a 2- (4-methoxy-enyl) - (4- or 5-) imidazolyl group, a 4- (2,4-dichlorophenyl) - (2- or 5-) imidazolyl group, a 2- (2,4-, β-trifluorophenyl) - (4- or 5-) imidazolyl group, a 2- (3, 4-diphenylmethyl) - (4- or 5-) imidazolyl, a 5- (3,4, 6-trimethylphenyl) - (2- or 4-) A-idazolyl group, a 2- (3,4-dimethoxyphenyl) group ) - (4- or 5-) imidazolyl, a 4- (2,4,6-trimethoxyphenyl) - (2- or 5-) imidazolyl group, a 5- (3-chloro-4-trifluoromethoxy-enyl) - ( 2- or 4-) imidazolyl or the like.

A phenylsulphinyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C 1 -C 6 alkyl group with halogen and a substituted or unsubstituted C 1 -C 4 alkoxy group halogen can be substituted) is an unsubstituted phenylsulfinyl group or having 1 to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen and an alkoxy group Cl-Cβ substituted or unsubstituted with halogen as defined above, examples of which include a phenylsulfinyl group, a 2-fluorophenylsulfinyl group, a 3-fluorophenylsulfinyl group, a 4-fluorophenylsulfinyl group, a 2-chlorophenylsulfinyl group, a 3-group -chlorophenylsulfinyl, a 4-chlorophenylsulfinyl group, a 2-bromophenylsulfinyl group, a 3-bromophenylsulfinyl group, a 4-bromophenylsulfinyl group, a 2-iodophenylsulfinyl group, a 3-yodofenilsulfinilo group, a 4-yodofenilsulfinilo group, a 2, 3-difluorofenilsulfinilo, 3.4-difluorofenilsulfinilo group, a 3, 5-difluorofenilsulfinilo, a 2, 4-difluorofenilsulfinilo, a 2,6-difluorofenilsulfinilo group , a 2,3-dichlorophenylsulfinyl group, a 3,4-dichlorophenylsulfinyl group, a 3,5-dichlorophenylsulfinyl group, a 2,4-dichlorophenylsulfinyl group, a 2,6-dichlorophenylsulfinyl group, a 3,4,5-trifluorophenylsulfinyl group , a 3,4,5-trichlorophenylsulfinyl group, a 2,4,6-trifluorophenylsulfinyl group, a 2,4,6-trichlorophenylsulfinyl group, a 2-fluoro-4-bromophenylsulfinyl group, a 4-chloro-3 group fluorophenylsulfinyl, a 2, 3, 4-trichlorophenylsulfinyl group, a 2,3,4,5,6-pentafluorophenylsulfinyl group, a 2,4,6-trimethylphenylsulfinyl group, a 4-n-butylphenylsulfinyl group, a group 2, 4- dimethylphenylsulfinyl, a 2,3-dimethylphenylsulfinyl group, a 2,6-dimethylphenylsulfinyl group, a 3,5-dimethylphenylsulphinyl group, a 2,5-group - dimetilfenilsulfinilo, 3,5-ditrifluorometilfenilsulfinilo group, a 4-n-butoxifenilsulfinilo group, 2, 4-dimetoxifenilsulfinilo, a 2, 3-dimetoxifenilsulfinilo, a 2,6-dimetoxifenilsulfinilo group, a 3, 5-dimetoxifenilsulfinilo a ditrifluorometoxifenilsulfinilo 3,5-chloro-4-metoxifenilsulfinilo 3-chloro-4-trifluorometoxifenilsulfinilo 2-group 2, 5-dimetoxifenilsulfinilo a 2,4,6-trimetoxifenilsulfinilo group, a group, a group, a group, a 3 -methyl-4-fluorophenylsulfinyl, a 4-bromo-3-trifluoromethylphenylsulfinyl group, a 2-methylphenylsulfinyl group, a 3-methylphenylsulfinyl group, a 4-methylphenylsulfinyl group, a 2-methyl-3-chlorophenylsulfinyl group, a 3-methyl group -4-clorofenilsulfinilo-chloro-4-methylphenylsulfinyl 2, a group, a-methyl-3-fluorofenilsulfinilo 2, a 2-trifluorometilfenilsulfinilo group, a 3- trifluorometilfenilsulfinilo, m 4-trifluorometilfenilsulfinilo group, m group, 2-pentafluoroetilfenilsulfinilo group, a 3-pentaf group Luoroethylphenylsulfinyl, a 4-pentafluoroethylphenylsulfinyl group, a 2-isopropylphenylsulfinyl group, a 3-isopropylphenylsulfinyl group, a 4-isopropylphenylsulfinyl group, a 2-tert-butylphenylsulfinyl group, a 3-tert-butylphenylsulfinyl group, a 4-tert-butylphenylsulfinyl group, un-sec-butilfenilsulfinilo 2 group, a 3-sec-butilfenilsulfinilo group, 4-sec-butilfenilsulfinilo group, 2-n-heptafluoropropilfenilsulfinilo a-n-heptafluoropropilfenilsulfinilo 3 group, a 4-n-heptafluoropropilfenilsulfinilo, a group 4-n-pentilfenilsulfinilo group, a 4-n-hexilfenilsulfinilo group, a 2-metoxifenilsulfinilo group, a 3-metoxifenilsulfinilo group, a 4-metoxifenilsulfinilo group, a 3-chloro-2-metoxifenilsulfinilo group, a 2-fluoro-3- methoxyphenylsulfinyl, a 2-fluoro-4-methoxyphenylsulfinyl group, a 2,3,4-trifluorophenylsulfinyl group, a 2-trifluoromethoxyphenylsulfinyl group, a 3- trifluoromethoxyphenylsulfinyl group, a 4-trifluoromethoxyphenylsulfinyl group, a group or 3-fluoro-2-trifluoromethoxy-phenylsulfinyl, a 2-fluoro-3-trifluoromethoxyphenylsulfinyl group, a 3-fluoro-4-trifluoromethoxyphenylsulfinyl group, a 3-chloro-2-trifluoromethoxyphenylsulfinyl group, a 2-chloro-3-trifluoromethoxyphenylsulfinyl group, a 3-chloro-4-trifluoromethoxyphenylsulfinyl group a-pentafluoroetoxifenilsulfinilo 2 pentafluoroetoxifenilsulfinilo 3-pentafluoroetoxifenilsulfinilo 4-chloro-pentafluoroetoxifenilsulfinilo 3--2-chloro-3-pentafluoroetoxifenilsulfinilo 2-chloro-4-pentafluoroetoxifenilsulfinilo 3-group, an group, an group, an group, an group, an group, 2-isopropoxyphenylsulfinyl group, a 3-isopropoxyphenylsulfinyl group, a 4-isopropoxyphenylsulfinyl group, a 2-tert-butoxyphenylsulfinyl group, a 3-tert-butoxyphenylsulfinyl group, a 4-tert-butoxyphenylsulfinyl group, a 2-sec-butoxyphenylsulfinyl group, a 3-sec-butoxyphenylsulfinyl group, a 4-sec-butoxyphenylsulfinyl group, a 2-n-heptafluoropropoxyphenylsulfinyl group, a 3-n-heptafluoropropoxyphenylsulfinyl group, a 4-n-heptafluoropropoxife group nylsulfinyl, a 4-n-pentoxyphenylsulfinyl group, a 4-n-hexyloxyphenylsulfinyl group or the like.

A C1-C6 alkyl pyridyl group [wherein, in the pyridyl ring, at least one phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-alkyl group C6 substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] includes, in addition to a Cl-Cβ pyridyl alkyl group as described above, a Cl-Cß alkyl group pyridyl having a straight or branched alkyl group containing 1 to 6 carbon atoms in the alkyl moiety [wherein, in the pyridine ring, 1 to 3 phenyl groups as described above (wherein, in the phenyl ring, to 5, preferably 1 to 3 substituents selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen can be substituted) p it can be substituted], for example, a 2- (4-trifluoromethoxyphenyl) - (3-, 4-, 5- or 6-) pyridylmethyl group, a 2- (4-trif luoromethylphenyl) - (3- , 4-, 5- or 6-) pyridylmethyl, a 2- (4-methoxyphenyl) - (3-, 4-, 5- or 6-) pyridylmethyl group, a 2- (4-methylphenyl) - (3 -, 4-, 5- or 6-) pyridylmethyl, a 2- (3-chloro-4-f luorofenyl) - (3-, 4-, 5- or 6-) pyridylmethyl group, a group 2- (2 , -dimethoxyphenyl) - (3-, 4-, 5- or 6-) pyridylmethyl, a 2- (3,4-, 5-trimethoxyphenyl) - (3-, 4-, 5- or 6-) pyridylmethyl group, a group 2 - (2,4-dimethylphenyl) - (3-, 4-, 5- or 6-) pyridylmethyl, a 2- (2,4-, 6-trimethylphenyl) - (3-, 4-, 5- or 6-) group ) pyridylmethyl, a 2- (2,4,6-trichlorophenyl) - (3-, 4-, 5- or 6-) pyridylmethyl group, a 2- (3-chloro-4-trifluoromethoxyphenyl) - (3-, 4-, 5- or 6-) pyridylmethyl, a 2, 4, 6-triphenyl- (3- or 5-) pyridylmethyl group, a 2,5-diphenyl- (3-, 4- or 6-) pyridylmethyl group or Similar. A 4H-1, 3-benzodioxinyl group (wherein, in the 4H-1, 3-benzodioxine ring, at least one halogen atom can be substituted) includes a 4H-1,3-benzodioxinyl group (wherein, in the ring 4H-1, 3-benzodioxine, 1 to 4 halogen atoms can be substituted), for example, a group (2-, 4-, 5-, 6-, 7- or 8-) 4H-1, 3- benzodioxinyl, a 2,2,4,4-tetrafluoro- (5-, 6-, 7- or 8-) 4H-1,3-benzodioxinyl group, a 2-chloro- (2-, 4-, 5-) group , 6-, 7- or 8-) 4H-1, 3-benzodioxinil, a 4-bromo- (2-, 4-, 5-, 6-, 7- or 8-) 4H-1,3-benzodioxinyl group , a 2, 4-dichloro- (2-, 4-, 5-, 6-, 7- or 8-) 4H-1, 3-benzodioxinyl group, a 2, 4, 6-trifluoro- (2-, 4-, 5-, 7- or 8-) 4H-1, 3-benzodioxinyl or the like. The methods for preparing the compounds of the present invention are explained in detail below.

Reaction scheme 1 (2) (4a) (1) wherein R1, R2 and n are the same as above, and X1 represents a halogen atom or nitro group. According to the reaction scheme 1, the compound of the present invention represented by the general formula (1) is produced by reacting a 4-nitroimidazole compound represented by the general formula (2) with an epoxy compound represented by the formula (3a) in the presence or absence of a basic compound to obtain a compound represented by the general formula (4a), and then subjecting the obtained compound to a ring-closure reaction. The molar ratio of the compound of the general formula (2) to the compound of the general formula (3a) can generally be between 1: 0.5 and 1: 5, and preferably between 1: 0.5 and 1: 3. Known compounds can be widely used as a basic compound in the present. Examples of such a basic compound include inorganic basic compounds such as a metal hydride, metal alcoholate, hydroxide, carbonate or hydrogen carbonate, and organic basic compounds such as acetate. Specific examples of a metal hydride include sodium hydride and potassium hydride. Specific examples of a metal alcoholate include sodium methoxide, sodium ethoxide and potassium tert-butoxide. Specific examples of a hydroxide include sodium hydroxide and potassium hydroxide. Specific examples of a carbonate include sodium carbonate and potassium carbonate. Specific examples of a hydrogen carbonate include sodium hydrogen carbonate and potassium hydrogen carbonate. In addition to the above compounds, sodium amide and the like may also be included in the inorganic basic compounds. Specific examples of acetate include sodium acetate and potassium acetate. In addition to these compounds, specific examples of organic basic compounds include triethylamine, trimethylamine, diisopropylethylamine, pyridine, dimethylaniline, 1-methylpyrrolidine, N-methylmorpholine, 1,5-diazabicyclo- [4.3.0] noneno-5 (DBN), 1 , 8-diazabicyclo [5.4.0] undecene-7 (DBU), and 1,4-diazabicyclo [2.2.2] octane (DABCO). The molar ratio of the above basic compound to the compound of the general formula (2) can be generally between 0.1: 1 and 2: 1, preferably between 0.1: 1 and 1: 1, and more preferably between 0.1: 1 and 0.5: 1 The reaction of the compound of the general formula (2) with the compound of the general formula (3a) is generally carried out in an appropriate solvent. Common solvents can be widely used as the above solvent, since this does not inhibit the reaction. Examples of such a solvent include polar aprotic solvents such as dimethylformamide (DMF), dimethyl sulfoxide (DMSO) or acetonitrile, ketone solvents such as acetone or methyl ethyl ketone, hydrocarbon solvents such as benzene, toluene, xylene, tetralin or liquid paraffin, alcohol such as methanol, ethanol, isopropanol, n-butanol or tert-butanol, ether solvents such as tetrahydrofuran (THF), dioxane, dipropyl ether, diethyl ether or diglyme, ester solvents such as ethyl acetate or methyl acetate , and mixed solvents thereof. It can contain water in these solvents. The reaction of the compound of the general formula (2) with the compound of the general formula (3a) is carried out, for example, as follows: The compound of the general formula (2) is dissolved in a reaction solvent, and While stirring, a basic compound is added to the mixture cooled on ice or to room temperature (30 ° C). Subsequently, the mixture is stirred at room temperature up to 80 ° C for 30 minutes up to 1 hour, and the compound of the general formula (3a) is then added thereto. Subsequently, the mixture is further stirred generally at room temperature to 100 ° C, and preferably 50 ° C to 80 ° C, generally for 30 minutes to 60 hours, and preferably for 1 to 50 hours. The compound (2) used as a starting material is known. The compound (3a) which includes a novel compound, and a method for producing the compound will be explained later. The compound of the present invention represented by the general formula (1) is produced by subjecting the compound represented by the general formula (4a) to a ring closure reaction. The ring closure reaction is carried out by dissolving the above obtained compound represented by the general formula (4a) in a reaction solvent and then adding a basic compound thereto followed by stirring. In the present, as a reaction solvent and a basic compound, the same reaction solvent and the same basic compound as used in the above reaction of the compound of the general formula (2) can be used with the compound of the general formula ( 3a). The molar ratio of the basic compound to the compound of the general formula (4a) is generally equal to 1: 1 or higher, preferably between 1: 1 and 5: 1, and more preferably between 1: 1 and 2: 1. The temperature Reaction for the ring closure reaction is generally from 0 ° C to 150 ° C, preferably room temperature up to 120 ° C, and more preferably 50 ° C to 100 ° C. The reaction time is usually 30 minutes up to 48 hours, preferably 1 to 24 hours, and more preferably 1 to 12 hours. In the present invention, the reaction mixture can be directly subjected to the following ring-closure reaction without isolating the compound of the general formula (4a) generated as a result of the reaction of the compound of the general formula (2) with the compound of the general formula (3a). For example, the compound of the general formula (2) is reacted with the compound of the general formula (3a) at room temperature up to 80 ° C, and subsequently, a basic compound is added to the obtained reaction mixture followed by stirring at 50 ° C to 100 ° C. Otherwise, after the compound of the general formula (2) is reacted with the compound of the general formula (3a) at room temperature up to 80 ° C, the obtained reaction mixture is concentrated, and the residue is dissolved in a superior boiling solvent. Subsequently, a basic compound is added to the obtained solution followed by stirring at 50 ° C to 100 ° C, so that a compound of interest represented by the general formula (1) is produced. Alternatively, in the reaction of the compound of the general formula (2) with the compound of the general formula (3a), a basic compound is used at a molar ratio of the basic compound to the compound (2) which is between 0.9: 1 and 2. : 1. The stirring is carried out at 50 ° C to 100 ° C, so that the reaction of the compound of the general formula (2) with the compound of the general formula (3a) is carried out in a simple process to produce a compound of interest represented by the general formula (1). Reaction scheme 2 (3b) (4c) (1w) wherein X1 is the same as above, R1A represents a hydrogen atom or an alkyl group Cl-6 and R2A represents a group of (a) to (y) as defined above. Accordingly with the reaction scheme 2, the compound of the present invention represented by the general formula (lw) is produced by reacting a compound represented by the general formula (3b) with a compound represented by the general formula (5) or a salt thereof, so that a compound represented by the general formula (4c) is obtained, and then subjecting the obtained compound represented by the general formula (4c) to a ring-closing reaction, in the presence of a basic compound . The compound (3b) is new, and a method for producing the compound will be explained later (reaction scheme 6). In addition, the compound (5) includes a novel compound. An example of the methods for producing the above compound will be described later in Reference Example 2. The molar ratio of the compound of the general formula (3b) to the compound of the general formula (5) may generally be between 1: 0.5. and 1: 5, and preferably between 1: 0.5 and 1: 2. The reaction of the compound of the general formula (3b) with the compound of the general formula (5) is carried out in the presence of a basic compound in a solvent appropriate. As a basic compound and a reaction solvent, the same basic compound and the same reaction solvent as used in the above reaction of the compound of the general formula (2) can be used with the compound of the general formula (3a) The molar ratio of the basic compound to the compound of the general formula (3b) is generally a catalytic amount, preferably between 0.1: 1 and 3: 1, and more preferably between 0.1: 1 and 2: 1. The salt of the compound (5) it can be used instead of using the compound (5) and a basic compound. Examples of such a salt include alkali metal salts such as a sodium salt or a potassium salt of the compound (5).

The reaction of the compound of the general formula (3b) with the compound of the general formula (5) is carried out, generally at room temperature up to 150 ° C, preferably at room temperature up to 120 ° C, and more preferably at room temperature up to 80 ° C. The reaction time is generally 10 minutes up to 48 hours, preferably 10 minutes up to 24 hours, and more preferably 10 minutes up to 2 hours. The compound of the present invention represented by the general formula (lw) is produced by subjecting the compound represented by the general formula (4c) to a ring closure reaction. The ring-closing reaction is carried out by dissolving the above-obtained compound represented by the general formula (4c) in a reaction solvent and then adding a basic compound thereto followed by stirring at a certain temperature. In the present, as a reaction solvent and a basic compound, the same reaction solvent and the same basic compound as used in the above reaction of the compound of the general formula (3b) can be used with the compound of the general formula ( 5) . The molar ratio of the basic compound to the compound of the general formula (4c) is generally equal to 1: 1 or higher, preferably between 1: 1 and 5: 1, and more preferably between 1: 1 and 2: 1.

The reaction temperature for the ring closure reaction is generally 0 ° C to 150 ° C, preferably room temperature to 120 ° C, and more preferably 50 ° C to 100 ° C. The reaction time is generally 10 minutes up to 48 hours, preferably 10 minutes up to 24 hours, and more preferably 20 minutes up to 4 hours. In the present invention, the reaction mixture can be directly subjected to the following ring-closure reaction without isolating the compound of the general formula (4c) generated as a result of the reaction of the compound of the general formula (3b) with the compound of the general formula (5), so that a compound of interest is produced which is the compound of the present invention represented by the general formula (lw). If a basic compound is used for the compound (5) a molar ratio of equal to 1: 1 or higher and the reaction is carried out at 50 ° C to 100 ° C, the compound of the present invention represented by the General formula (lw) can be produced in a simple process without isolating an intermediate (4c). In the case of using the alkali metal salt (for example, a sodium salt or a potassium salt) of the compound (5), it is thought that it may be the same.

Reaction scheme 3 (6) (1w) where R, 1A, R and n are the same as above, and R 15 represents an alkylsulfonyl Cl-6 group, or a benzenesulfonyl group which may be substituted Cl-6 alkyl group in the benzene ring. Here, an alkylsulfonyl Cl-6 group is a group consisting of an alkyl group having 1 to 6 carbon atoms and a sulfonyl group, and an example of an alkylsulfonyl group Cl-6 includes a methanesulfonyl group, an ethanesulfonyl group , propansulfonyl group, butanesulfonyl group, pentanesulfonyl group, hexansulfonyl group and the like. Examples of a benzenesulfonyl group which may be substituted Cl-6 alkyl group in the benzene ring include a benzenesulfonyl group which may have 1 to 3 Cl-6 alkyl groups in the benzene ring, such as a benzenesulfonyl group, o-group toluenesulfonyl, m-toluenesulfonyl group, p-toluenesulfonyl group, 2-ethylbenzenesulfonyl group, 3-ethylbenzenesulfonyl group, 4-ethylbenzenesulfonyl group, 2-propyl-benzenesulfonyl group, 3-propylbenzenesulfonyl group, 4-propylbenzenesulfonyl group, 2, 3-dimethyl group -benzenesulfonyl, group 2, 4-dimethylbenzenesulfonyl, group 2, 4,6-trimethylbenzenesulfonyl and the like. The reaction of the compound (6) with the compound represented by the general formula (5) is carried out in an appropriate solvent in the presence of a basic compound. Any known solvent can be used herein, since it does not inhibit the present reaction. Examples of such a solvent include water, polar aprotic solvents such as DMF, DMSO or acetonitrile, hydrocarbon solvents such as benzene, toluene, xylene, tetralin, liquid paraffin or cyclohexane, alcohol solvents such as ethanol, isopropanol, n-butanol or tert-butanol, ether solvents such as THF, dioxane, dipropyl ether, diethyl ether or diglyme, ethyl acetate, acetone, and mixed solvents thereof. As a basic compound, the same basic compound as used in the above reaction of the compound of the general formula (2) can be used with the compound of the general formula (3a). The molar ratio of the basic compound to the compound (6) is generally equal to 1: 1 or higher, preferably between 1: 1 and 5: 1, and more preferably between 1: 1 and 2: 1. The molar ratio of the compound represented by the general formula (5) the compound (6) can generally be equal to 1: 1 or higher, preferably between 0.9: 1 and 2: 1, and more preferably between 0.9: 1 and 1.5: 1. The reaction temperature it is generally room temperature up to 150 ° C, preferably room temperature up to 100 ° C, and more preferably 60 ° C up to 100 ° C. The reaction time is generally 10 minutes up to 24 hours, preferably 10 minutes up to 12 hours, and more preferably 20 minutes up to 7 hours. Next, the methods for preparing the starting materials and intermediates to obtain the compounds of the present invention are explained. Reaction scheme 4 (6) wherein R1A, R15 and n are the same as above, R16 represents a Cl-6-alkoxy Cl-6 alkoxy group or a Cl-6 alkanoyloxy group, and X2 represents a halogen atom. A compound of the general formula (8) is produced by the hydrolysis of a compound of the general formula (7).

The hydrolysis of the compound (7) is carried out under acidic conditions. The hydrolysis is carried out, for example, by suspending or dissolving the compound (7) in an appropriate solvent, and adding acid to the obtained solution followed by stirring at 0 ° C to 120 ° C. An example of a solvent used may include water, alcohol solvents such as methanol, ethanol, isopropanol or ethylene glycol, acetonitrile, acetone, toluene, DMF, DMSO, acetic acid, trifluoroacetic acid, and mixed solvents thereof. Examples of the acid used may include organic acids such as trifluoroacetic acid or acetic acid, and inorganic acids such as hydrochloric acid, bromic acid, hydrobromic acid or sulfuric acid. Organic acids such as trifluoroacetic acid or acetic acid can also be used as reaction solvents. The reaction temperature is generally 0 ° C to 120 ° C, preferably room temperature to 100 ° C, and more preferably room temperature to 80 ° C. The reaction time is generally 30 minutes up to 24 hours, preferably 30 minutes up to 12 hours, and more preferably 1 up to 8 hours.

The hydrolysis of the compound (7) can be carried out under a basic condition. The hydrolysis is carried out, for example, by suspending or dissolving the compound (7) in an appropriate solvent, and adding base to the obtained solution followed by stirring at 0 ° C to 120 ° C. An example of a solvent used may include water, alcohol solvents such as methanol, ethanol, isopropanol or ethylene glycol, and mixed solvents thereof. Examples of the base used may include alkali metal hydroxides such as sodium hydroxide or potassium hydroxide, alkali metal carbonates such as sodium carbonate or potassium carbonate, and acetates such as sodium acetate. The reaction temperature is generally 0 ° C to 120 ° C, preferably room temperature to 100 ° C, and more preferably room temperature to 80 ° C. The reaction time is generally 30 minutes up to 24 hours, preferably 30 minutes up to 12 hours, and more preferably 1 up to 8 hours. For the reaction of the compound (8) with the compound (9), the reaction conditions for the common sulfonylation reaction of the alcohol can be widely applied. For example, the compound (8) is dissolved in an appropriate solvent, and the compound (9) is added to the solution obtained in the presence of a basic compound followed by stirring at 0 ° C to 150 ° C, so that the compound (6) can be obtained. Any known solvent can be used herein, since it does not inhibit the sulfonylation reaction. Examples of such a solvent include halogenated hydrocarbon solvents such as methylene chloride or chloroform, polar aprotic solvents such as DMF, DMSO or acetonitrile, aromatic hydrocarbon solvents such as benzene, toluene or xylene, hydrocarbon solvents such as tetralin, liquid paraffin. or cyclohexane, ether solvents such as THF, dioxane, dipropyl ether, diethyl ether 0 diglyme, ethyl acetate, acetone, and mixed solvents thereof. The compound (9) is used to the compound (8) at a molar ratio of generally equal to 1: 1 or higher, preferably between 1: 1 and 2: 1, and more preferably between 1: 1 and 1.1: 1. a basic compound, the same basic compound as used in the above reaction of the compound of the general formula (2) can be used with the compound of the general formula (3a). The molar ratio of the basic compound to the compound (8) is generally equal to 1: 1 or higher, preferably between 1: 1 and 5: 1, and more preferably between 1: 1 and 2: 1. In the present sulfonylation reaction, 4-dimethylaminopyridine, 4- (1-pyrrolidinyl) pyridine or the like can be used as a catalyst. The reaction temperature is generally 0 ° C to 150 ° C, preferably 0 ° C to 100 ° C, and more preferably 0 ° C to 60 ° C. The reaction time is generally 30 minutes up to 48 hours, preferably 1 up to 24 hours, and more preferably 1 up to 4 hours.

Reaction scheme 5 (4b) (10) (4c) wherein R1A, R2A, R15, X1 and n are the same as above. The reaction to carry from the compound (4b) into a compound (10) is carried out, for example, under the same reaction conditions for the reaction to carry from the compound (8) to the compound (6) as shown in the reaction scheme 4. The reaction to carry from the compound (10) into the compound (4c) is carried out, for example, under the same reaction conditions for the reaction to carry from the compound (6) to the compound ( Iw) as shown in the reaction scheme 3.

Reaction scheme 6 (3b) (10a) wherein R1A, R15 and X1 are the same as above. The reaction to carry from a compound (10a) into a compound (3b) is carried out in an appropriate solvent in the presence of a basic compound. Any solvent can be widely used herein, since it does not inhibit the reaction. Examples of such solvent may include polar aprotic solvents such as DMSO or acetonitrile, hydrocarbon solvents such as benzene, toluene, xylene, tetralin or liquid paraffin, halogenated hydrocarbon solvents such as methylene chloride, chloroform or dichloroethane, ether solvents such as THF, dioxane, dipropyl ether, diethyl ether or diglyme, acetone , ethyl acetate, and mixed solvents thereof. The same basic compound as used in the reaction of the compound represented by the general formula above (2) with the compound represented by the general formula above (3a) can be used herein. The molar ratio of a basic compound to the compound (10a) can generally be equal to 1: 1 or higher, preferably between 1: 1 and 5: 1, and more preferably between 1: 1 and 2: 1. The reaction temperature for this reaction it is generally 0 ° C to 150 ° C, preferably 0 ° C to 100 ° C, and more preferably 0 ° C to 60 ° C. The reaction time is generally 30 minutes up to 48 hours, preferably 1 up to 24 hours, and more preferably 1 up to 4 hours. Reaction scheme 7 (11) (3a) (12) where R1, R2 and n are the same as above. The reaction for carrying from a compound (11) into a compound (3a) is carried out, for example, by treating the compound (11) with trimethylsulfoxonium iodide in a suitable solvent in the presence of a basic compound. Any solvent can be widely used herein, since it does not inhibit the reaction. Examples of such a solvent may include polar aprotic solvents such as DMSO or acetonitrile, hydrocarbon solvents such as benzene, toluene, xylene, -tetralin or liquid paraffin, ether solvents such as THF, dioxane, dipropyl ether, diethyl ether or diglyme , and mixed solvents thereof.

Examples of a basic compound may include sodium hydride, sodium amide, alcoholate metals such as sodium methoxide, sodium ethoxide or potassium tert-butoxide. The molar ratio of a basic compound to the compound (11) can generally be equal to 1: 1 or higher, preferably between 1: 1 and 3: 1, and more preferably between 1: 1 and 1.5: 1. In addition, the molar ratio of trimethylsulfoxonium iodide to the compound (11) ) can generally be equal to 1: 1 or higher, preferably between 1: 1 and 3: 1, and more preferably between 1: 1 and 1.5: 1. The reaction temperature for this reaction is generally 0 ° C to 80 ° C, preferably 10 ° C to 50 ° C, and more preferably 20 ° C to 35 ° C. The reaction time is generally 1 to 24 hours, preferably 1 to 12 hours, and more preferably 1 to 4 hours. The reaction to carry from a compound (12) to the compound (3a) is carried out, for example, by treating the compound (12) with peroxide in an appropriate solvent. Any reaction solvent can be widely used herein, since it does not inhibit the reaction. Examples of such solvents may include water, alcohol solvents such as methanol or ethanol, polar aprotic solvents such as DMF, DMSO or acetonitrile, hydrocarbon solvents such as benzene, toluene, xylene, tetralin, liquid paraffin or cyclohexane, halogenated solvents of hydrocarbons such as methylene chloride, chloroform or dichloroethane, ether solvents such as THF, dioxane, dipropyl ether, diethyl ether or diglyme, and mixed solvents thereof. Examples of peroxide include metachloroperbenzoic acid (mCPBA), perbenzoic acid, peracetic acid and hydrogen peroxide. The molar ratio of peroxide to compound (12) can be generally between 1: 1 and 2: 1, preferably between 1: 1 and 1.5: 1, and more preferably between 1: 1 and 1.3: 1. The reaction temperature for this reaction is generally 0 ° C to 80 ° C, preferably 0 ° C to 50 ° C, and more preferably 20 ° C to 35 ° C. The reaction time is generally 10 minutes up to 24 hours, preferably 1 up to 12 hours, and more preferably 1 up to 8 hours. For example, one type of the compounds (3a) is optically active, the compound (12) is produced as follows. Such an optically active compound (3a) can be produced by what is called Sharpless epoxidation. That is, the compound can be produced by epoxidation with cumene hydroperoxide or tert-butyl hydroperoxide, in the coexistence of Ti (0-iso-C3H7) and optically active C1-C6 alkyl tartarate such as diethyl tartarate (form D- or L-) as a catalyst, instead of using a peroxide in the above reaction to carry the compound (12) to the compound (3a). Any solvent can be widely used herein, since it does not inhibit the reaction. Examples of such solvent may include polar aprotic solvents such as acetonitrile, hydrocarbon solvents such as benzene, toluene, xylene, tetralin, liquid paraffin or cyclohexane, halogenated hydrocarbon solvents such as methylene chloride, chloroform or dichloroethane, ether solvents such as THF, dioxane, dipropyl ether, diethyl ether or diglyme, and mixed solvents thereof. The molar ratio of cumene hydroperoxide or tert-butyl hydroperoxide to compound (6) can generally be between 0.1: 1 and 2: 1, preferably between 0.1: 1 and 1.5: 1, and more preferably between 0.1: 1 and 1: 1. The molar ratio of Ti (0-iso-C3H) to compound (12) may be generally between 0.1: 1 and 2: 1, preferably between 0.1: 1 and 1.5: 1, and more preferably between 0.1: 1 and eleven.

The molar ratio of optically active Cl-Cß tartarate (form D- or L-) to compound (12) can generally be between 1: 1 and 2: 1, preferably between 1: 1 and 1.5: 1, and more preferably between 1: 1 and 1.3: 1.

The reaction temperature for this reaction is generally -50 ° C to 30 ° C, preferably -20 ° C to 20 ° C, and more preferably -20 ° C to 5 ° C. The reaction time is generally 1 to 48 hours, preferably 4 to 24 hours, and more preferably 4 to 12 hours.

Reaction scheme 8 (13) (3c) wherein R1A, R2A, R15 and n are the same as above. The reaction to carry from a compound (13) into a compound (3c) is carried out, for example, under the same reaction conditions for the reaction to carry the compound (ß) to the compound (lw) as shown in the reaction scheme 3.

Reaction scheme 9 (where R1A, X, n,, W and o are the same as above.

R7a represents a hydrogen atom, hydroxyl group, Cl-β alkoxy group or phenyl group (which can be substituted with halogen atom (s) in the phenyl ring). The dotted line in the piperidine ring represents a bond that can be a double bond. When the dotted line is a double bond, a hydroxyl group must be replaced in the piperidine ring. RSa represents a tetrahydropyranyl group. R17 represents a Cl-6 alkyl group or phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen, and Cl-alkoxy group) 6 substituted or unsubstituted with halogen in the phenyl ring). M represents an alkali metal such as sodium, potassium, etc.). The reaction for carrying from a compound (14) into a compound (15) is carried out in the presence or absence of a suitable solvent in the presence of an acid. Any solvent can be widely used herein, as long as it does not affect the reaction. Examples of such solvents may include water, halogenated hydrocarbons such as dichloromethane, chloroform or carbon tetrachloride, lower alcohols such as methanol, ethanol or isopropanol, ketones such as acetone or methyl ethyl ketone, ethers such as dioxane, tetrahydrofuran, ethylene glycol monomethyl ether or ethylene glycol dimethyl ether, aliphatic acids such as formic acid or acetic acid, in mixed solvents thereof. Examples of such acid may include, for example, mineral acids such as hydrochloric acid, sulfuric acid or hydrobromic acid, organic acids such as formic acid, trifluoroacetic acid or acetic acid, or aromatic sulfonic acids such as p-pyridinium p-toluenesulfonic acid, p-toluenesulfonic acid or the like. Although the amount of such acid used can be broadly selected from a wide range without any particular limitation, this can generally be from about 0.1-10 moles up to 1 mole of the compound used (14), preferably from about 0.1-2 moles. The suitable reaction procedure is generally from about 0-200 ° C, preferably room temperature to about 150 ° C, and is generally completed about 0.5-50 hours. The reaction of the compound (15) with the compound (16) or (17) can be carried out in the presence or absence of a basic compound, preferably in the absence of a suitable inert solvent or without any solvent. Examples of a basic compound used herein include, for example, organic bases such as triethylamine, trimethylamine, pyridine, dimethylaniline, N-ethyldiisopropylamine, dimethylaminopyridine, N-methylmorpholine, 1,5-diazabicyclo [4.3.0] noneno-5 (DBN), 1,8-diazabicyclo [5.4.0] undecene-7 (DBU) or 1,4-diazabicyclo [2.2.2] octane (DABCO), and organic bases including carbonates such as sodium carbonate, potassium carbonate , sodium hydrogen carbonate or potassium hydrogen carbonate, metal hydroxides such as sodium hydroxide, potassium hydroxide or calcium hydroxide, potassium hydride, sodium hydride, potassium, sodium, sodium amide, metal alcoholates such as sodium methylate or sodium ethylate, or the like. Examples of a solvent used include, for example, halogenated hydrocarbons such as chloroform, dichloromethane, dichloroethane or carbon tetrachloride, aromatic hydrocarbons such as benzene, toluene or xylene, ethers such as diethyl ether, diisopropyl ether, tetrahydrofuran or dimethoxyethane, such esters such as methyl acetate, ethyl acetate or isopropyl acetate, alcohols such as methanol, ethanol, isopropanol, propanol, butanol, 3-methoxy-1-butanol, ethyl cellosolve or methyl cellosolve, and polar aprotic solvents such as acetonitrile, pyridine, acetone, water, N, N-dimethylacetamide, N, N-dimethylformamide, dimethylsulfoxide or hexamethylphosphoric triamide or mixed solvents thereof. The molar ratio of the compound (16) or (17) to the compound (15) can generally be between about 1: 1 and 5: 1 each, preferably between about 1: 1 and 3: 1. The reaction is generally carried out at a temperature of about 0-200 ° C, preferably room temperature to about 150 ° C, generally for about 5 minutes to 30 hours required. In the reaction system, boron compounds such as boron trifluoride etherate complex and halogenated copper compounds such as copper (I) chloride may be added. In the reaction of the compound (15) with the compound (17), this proceeds sale when an organic acid such as trifluoroacetic acid is added in the reaction system.

Reaction scheme 10 (where R1A, X, n, m, W, R7a, X2 and I are the same as above.) Two Ws in the general formulas (le) to (Ig) may be the same or different, R9a represents a hydrogen atom) R10a represents a hydrogen atom; the Cl-6 alkyl group which may have a hydroxyl group as a substituent; alkanoyl group Cl-6; alkoxycarbonyl group Cl-6; phenyl, alkoxycarbonyl group Cl-6 (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-6 alkyl group with halogen and substituted or non-substituted Cl-6 alkoxy group) substituted with halogen, as a substituent on the phenyl ring); phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen, Cl-6 alkoxy group substituted or unsubstituted with halogen, amino group which may have a group selected from the group consisting of an alkanoyl Cl-6 group and Cl-6 alkyl group as a substituent, alkoxycarbonyl Cl-6 group, phenyl group, phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen, can be substituted), aminosulfonyl group, group 1,2 , 3,4-tetrahydroquinolyl (which can be substituted with at least one oxo group as a substituent on the 1,2,3,4-tetrahydroquinoline ring), alkylsulfonyl group Cl-6, C 3-8 cycloalkyl group, nitro group, group cyano, alkylthio Cl-6 group, phenylsu group lfonyl (which can be substituted with at least one selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen, as a substituent in the phenyl ring), hydroxyl group-substituted Cl-6 alkyl group and a group: (wherein Wi represents an alkylene group Cl-6, R "L and R represent an alkoxy Cl-6 group which may be the same or different) may be substituted), an alkyl group Cl-6 phenyl (wherein, in the phenyl ring at least one selected from the group consisting of an alkylene dioxy Cl-4 group, phenyl group (which may be substituted with at least one selected from the group consisting of a halogen atom, substituted or unsubstituted C1-alkyl group) substituted with halogen, Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl ring), the group -N (R11) R12A (R11A and R12A represents a hydrogen atom, Cl-6 alkyl group or phenyl group which can be be the same or different, and R11A and R12A can be combined with one another in conjunction with an adjacent nitrogen atom through a nitrogen atom, oxygen atom or sulfur atom or not through these to form a saturated heterocycle of 5 to 7 members), phenoxy group (which can be substituted with at least one selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen, Cl-β alkoxy group substituted or unsubstituted with halogen on the phenyl ring), alkoxy phenyl Cl- group 6, Cl-6 alkoxy group substituted with an amino group which may have a Cl-6 alkyl group as a substituent, halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen, and Cl-10 alkoxy group substituted or not substituted with halogen, can be substituted as a substituent); benzofuryl alkyl group Cl-β (which can be substituted with at least one selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen, Cl-6 alkoxy group substituted or unsubstituted with halogen in the benzofuran ring); phenylsulfonyl group (which can be substituted with at least one selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen, Cl-6 alkoxy group substituted or unsubstituted with halogen and alkylene dioxy Cl-4 group in the phenyl ring); phenoxydicarbonyl group (which can be substituted with at least one selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen, as a substituent in the phenyl ring); alkenyl phenyl group C2-6 (which can be substituted with at least one selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl ring); Cl-6 alkyl group substituted with Cl-6 alkoxy; C2-6 alkenyl group; C2-6 alkanoyl group substituted with Cl-6 alkoxy; Cl-6 alkyl group substituted with C3-8 cycloalkyl; alkyl group Cl-6 phenoxy (which can be substituted with at least one selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl ring); benzoyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl ring); phenylcarbamoyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-β alkyl group with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl ring); pyridyl group; Cl-6 alkyl pyridyl group; Cl-6-imidazolyl alkyl group; group 1, 2, 3, 4-tetrahydroquinolyl (which can be substituted with at least one group selected from the group consisting of an oxo group and Cl-6 alkyl group as a substituent on the 1,2,3,4-tetrahydroquinoline ring ); quinolyl group; indolyl group; amino group which may have a Cl-6 alkyl group as a substituent; indazolyl group; naphthyl group; C3-8 cycloalkyl group; Cl-6 alkyl group substituted with amino which may have a Cl-6 alkyl group as a substituent; Cl-6 alkyl group substituted with the cyano group; Cl-6 alkyl group with the furyl group; group: (wherein RR has a phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and alkoxy group Cl-6 substituted or unsubstituted with halogen, as a substituent on the phenyl ring)); or Cl-6 alkyl group substituted with piperazinyl (which can be substituted with at least one phenyl group (which can be substituted with at least one selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and alkoxy group Cl-6 substituted or unsubstituted with halogen on the phenyl ring) as a substituent on the piperazine ring).

R9b represents a hydrogen atom; Cl-6 alkyl group which may have a hydroxy group as a substituent; phenyl group (which can be substituted with at least one selected from the group consisting of an alkylene dioxy Cl-4 group, phenyl group (which can be substituted with at least one selected from the group consisting of a halogen atom, Cl-alkyl group) 6 substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted by halogen in the phenyl group), the group '-N (R11A) R12A (R11A and R12A represents a hydrogen atom, Cl-6 alkyl group or phenyl group which may be the same or different, and R11A and R12A may each be combined together with an adjacent nitrogen atom through a nitrogen atom, oxygen atom or sulfur atom or not through them to form a saturated heterocycle of 5 to 7 members), phenoxy group (which can be substituted with at least one selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and substituted Cl-6 alkoxy group)or unsubstituted with halogen in the phenyl ring), Cl-6 alkoxy phenyl group, Cl-6 alkoxy group substituted with amino which may have a Cl-6 alkyl group as a substituent, a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-10 alkoxy group substituted or unsubstituted with halogen, as a substituent on the phenyl ring); alkyl Cl-6 phenyl group (which may be substituted with at least one selected from the group consisting of an alkylene dioxy Cl-4 group, phenyl group (which may be substituted with at least one selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted by halogen and Cl-6 alkoxy group substituted or unsubstituted by halogen on the phenyl ring), the group -N (R11A) R12A (R11A and R12A represents a hydrogen atom, alkyl group Cl-6 or phenyl group which may be the same or different, and R11A and R12A may be combined with each other together with an adjacent nitrogen atom through a nitrogen atom, oxygen atom or sulfur atom or not through of them to form a saturated 5- to 7-membered heterocycle), phenoxy group (which can be substituted with at least one selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and alkoxy group)Cl-6 substituted or unsubstituted with halogen on the phenyl ring), Cl-6 alkoxy phenyl group, Cl-6 alkoxy group substituted with amino which may have a Cl-6 alkyl group as a substituent, halogen atom, alkyl group Cl-6 substituted or unsubstituted with halogen and Cl-10 alkoxy group substituted or unsubstituted with halogen, as a substituent on the phenyl ring); benzofuryl (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen, Cl-6 alkoxy group substituted or unsubstituted with halogen in the ring of benzofuran); alkyl group Cl-6 benzofuryl (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-6 alkyl group with halogen and substituted or unsubstituted Cl-6 alkoxy group with halogen in the benzofuran ring); Cl-6 alkyl group substituted with Cl-6 alkoxy; Cl-6 alkyl group substituted with C3-8 cycloalkyl; C3-8 cycloalkyl group; Cl-6 alkyl phenoxy group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-6 alkyl group with halogen and substituted or unsubstituted Cl-6 alkoxy group with halogen, as a substituent on the phenyl ring); pyridyl group; Cl-6 alkyl pyridyl group; imidazolyl group; Cl-6-imidazolyl alkyl group; Cl-6 alkyl group substituted with amino which may have a Cl-6 alkyl group as a substituent; Cl-6 alkyl group substituted with cyano; Cl-6 alkyl group substituted with furyl; Furyl group; piperazinyl group (which can be substituted with at least one phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and alkoxy group) Cl-6 substituted or unsubstituted with halogen on the phenyl ring) as a substituent on the piperazine ring); or Cl-6 alkyl group substituted with piperazinyl (which can be substituted with at least one phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted Cl-6 alkyl group or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen on the phenyl ring) as a substituent on the piperazine ring). R9c represents a Cl-6 alkyl group which may have a hydroxy group as a substituent; alkoxycarbonyl group Cl-6; alkoxycarbonyl Cl-6 phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-6 alkyl group with halogen and substituted or unsubstituted Cl-6 alkoxy group with halogen, as a substituent on the phenyl group); phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen, Cl-6 alkoxy group substituted or unsubstituted with halogen, group amino which can have a group from the group consisting of an alkanoyl group Cl-6 and alkyl group Cl-6 as a substituent, alkoxycarbonyl group Cl-6, phenyl group, phenoxy group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-6 alkyl group with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen, as a substituent on the phenyl ring), aminosulfonyl group, group 1 , 2, 3, 4-tetrahydroquinolyl (which can be substituted with at least one oxo group as a substituent on the 1, 2, 3, 4-tetrahydroquinoline ring), alkylsulfonyl Cl-6 group, C3-8 cycloalkyl group, nitro group , group cia no, alkylthio group Cl-6, phenylsulfonyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen, as a substituent on the phenyl ring), a Cl-6 alkyl group substituted with a hydroxyl group and a group: (wherein Wi represents an alkylene group Cl-6, and R11 and R12 represent a Cl-6 alkoxy group which may be the same or different)); an alkyl Cl-6 phenyl group (which can be substituted with at least one of the groups selected from the group consisting of an alkylene dioxy Cl-4 group, phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl ring), the group -N (R11A) R12A (R11A and R12A represents a hydrogen atom, Cl-6 alkyl group or phenyl group which may be the same or different, and R and R may be combined with each other together with an adjacent nitrogen atom through a nitrogen atom, oxygen atom or sulfur atom or not through them to form a 5- to 7-membered saturated heterocycle), phenoxy group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, alkyl group Cl -6 replaced or not substituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl ring), phenyl Cl-6 alkoxy group, amino-substituted Cl-6 alkoxy group which may have an Cl-6 alkyl group as a substituent, halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-10 alkoxy group substituted or unsubstituted with halogen, as a substituent on the phenyl ring); alkyl group Cl-6 benzofuryl (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-6 alkyl group with halogen and substituted or unsubstituted Cl-6 alkoxy group with halogen in the benzofuran ring); phenylsulfonyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen, Cl-6 alkoxy group substituted or unsubstituted with halogen and group alkylene dioxy Cl-4 substituted or unsubstituted with halogen in the phenyl ring); C2-6 alkenyl group phenyl (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-6 alkyl group with halogen and substituted or unsubstituted Cl-6 alkoxy group with halogen in the phenyl ring); Cl-6 alkyl group substituted with Cl-β alkoxy; C2-6 alkenyl group; Cl-6 alkyl group substituted with the C3-8 cycloalkyl group; alkyl group Cl-6 phenoxy (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-6 alkyl group with halogen and substituted or unsubstituted Cl-6 alkoxy group with halogen in the phenyl ring); pyridyl group; Cl-6 alkyl pyridyl group; Cl-6-imidazolyl alkyl group; Group 1, 2, 3, 4-tetrahydroquinolyl (which can be substituted with at least one group selected from the group consisting of an oxo group and Cl-6 alkyl group as a substituent on the 1,2,3,4-tetrahydroquinoline ring); quinolyl group; indolyl group; indazolyl group; naphthyl group; C3-8 cycloalkyl group; Cl-6 alkyl group substituted with amino which may have a Cl-6 alkyl group as a substituent; Cl-6 alkyl group substituted with cyano; Cl-6 alkyl group substituted with furyl; group: (wherein RR has a phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and substituted Cl-6 alkoxy group or not substituted with halogen, as a substituent on the phenyl ring)); or Cl-6 alkyl group substituted with piperazinyl (which can be substituted with at least one phenyl group (which can be substituted with at least one selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted by halogen on the phenyl ring) as a substituent on the piperazine ring). R9d represents a Cl-6 alkanoyl group; phenoxydicarbonyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-6 alkyl group with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl group); C2-6 alkanoyl group substituted with Cl-6 alkoxy or benzoyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and group Cl-6 alkoxy substituted or unsubstituted with halogen in the phenyl ring). R9e represents a phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl group). R18 represents a hydrogen atom or Cl-6 alkyl group. The dotted line in the piperidine ring represents a bond that can be a double bond. When the dotted line is a double bond, a group - (W) or NR9aR10a, group- (W) or N (CHR18R9b) R10a, group- (W) or NR9cR10a, group- (W) or NR9dR10 or group- (W) or N (CONHR9e ) R10a must be replaced. The total number of carbons of CHR18R9b builds the group -N (R10a) CHR18R9b in the general formula (Id) must not exceed 6. The reaction of the compound (lc) with the compound (16) is carried out in the presence of an agent reducer without a solvent or in a suitable solvent.

The molar ratio of the compound (16) to the compound (1c) can be generally at least 1: 1, preferably 1: 1 to a large excess. Examples of the solvents used in the reaction may include, for example, water, lower alcohols such as methanol, ethanol, isopropanol, butanol, tert-butanol or ethylene glycol, acetonitrile, aliphatic acids such as formic acid, acetic acid or trifluoroacetic acid. , ethers such as diethyl ether, tetrahydrofuran, dioxane, monoglyme or diglyme, aromatic hydrocarbons such as benzene, toluene or xylene, halogenated hydrocarbons such as dichloromethane, dichloroethane, chloroform, carbon tetrachloride or mixed solvents thereof, or the like. Examples of the reducing agents may include, for example, formic acid, alkali metal formats such as sodium formate, reducing agents such as sodium borohydride, sodium cyano borohydride, sodium triacetoxyborohydride, lithium aluminum hydride or mixtures thereof. reducing agents thereof, catalytic hydrogen reducing agents such as black palladium, palladium-carbon, platinum oxide, black platinum or Raney nickel, or the like. When formic acid and alkali metal formates are used as a reducing agent, the reaction temperature is generally appropriate from about room temperature to 200 ° C, preferably from about 50-150 ° C, and the reaction is completed in around 10 minutes to 10 hours. The molar ratio of formic acid to compound (le) can be large excess. Also, when a reducing agent was used, the reaction temperature is generally appropriate at -80-100 ° C, preferably at -80-70 ° C, and the reaction was completed in about 30 minutes to 100 hours. The molar ratio of the reducing agent to the compound (1c) can generally be between about 1: 1 and 20: 1, preferably between about 1: 1 and 6: 1. Particularly, when the lithium aluminum hydride is used as a reducing agent, the use of ethers such as diethyl ether, tetrahydrofuran, dioxane, monoglyme or diglyme and aromatic hydrocarbons such as benzene, toluene or xylene is preferred. Amines such as trimethylamine, triethylamine or N-ethyldiisopropylamine and molecular sieves such as 3A molecular sieve (MS-3A), 4A molecular sieve (MS-4A) or the like can be added in the reaction system. In addition, when the catalytic hydrogen reducing agents were used, the reaction can be carried out generally in a hydrogen atmosphere from about ordinary pressure to 20 atm, preferably from about ordinary pressure to 10 atm or in the presence of donor agents. hydrogen such as formic acid, ammonium formate, exo cycle or hydrazine hydrate, generally at a temperature of about -30-100 ° C, preferably around 0-60 ° C, and the reaction is generally completed from about 1 hour. -12 hours. The catalytic hydrogen reducing agents can generally be used in an amount of about 0.1-40% by weight based on the compound (lc), and preferably about 1-20% by weight. The reaction of the compound (Ic) with the compound (17) is generally conducted in an appropriate solvent in the presence or absence of a basic compound. Examples of an inerter solvent may include, for example, aromatic hydrocarbons such as benzene, toluene or xylene, ethers such as diethyl ether, tetrahydrofuran, dioxane, monoglyme or diglyme, halogenated hydrocarbons such as dichloromethane, dichloroethane, chloroform or carbon tetrachloride, lower alcohols such as methanol, ethanol, isopropanol, butanol, tert-butanol or ethylene glycol, aliphatic acids such as acetic acid, esters such as ethyl acetate or methyl acetate, ketones such as acetone or methylethyl ketone, acetonitrile, pyridine, dimethisulfoxide , N, N-dimethylformamide, hexamethylphosphoric triamide or mixed solvents thereof. The basic compounds can include, for example, carbonates such as sodium carbonate, potassium carbonate, sodium acid carbonate, potassium hydrogen carbonate or cesium carbonate, metal hydroxides such as sodium hydroxide, potassium hydroxide or calcium hydroxide, sodium hydride, hydride of potassium, potassium, sodium, sodium amide, metal alcoholates such as sodium methylate, sodium ethylate or sodium n-butoxide, organic bases such as pyridine, imidazole, N-ethyldiisopropylamine, dimethylaminopyridine, triethylamine, trimethylamine, dimethylaniline, N-methylmorpholine, 1,5-diazabicyclo [4.3.0] noneno-5 (DBN), 1,8-diazabicyclo [5.4.0] undecene-7 (DBU) or 1, -diazabicyclo [2.2.2] octane (DABCO) ) or a mixture thereof. The basic compounds can be used in molar ratio to the compound (le) of at least 1: 1, preferably between 1: 1 and 10: 1. The compound (17) is used in the molar ratio to the compound (le) of at least 1: 1, preferably between 1: 1 and 10: 1. The reaction is generally carried out at 0-200 ° C, preferably around 0-150 ° C, and is generally completed about 5 minutes to 80 hours. Alkali metal halides such as sodium iodide or potassium iodide may be added or the phase transfer catalysts may be added in the reaction system.

Examples of the phase transfer catalysts herein may include, for example, catalysts such as tetrabutylammonium chloride, tetrabutylammonium bromide, tetrabutylammonium fluoride, tetrabutylammonium iodide, tetrabutylammonium hydroxide, tetrabutylammonium acid sulfate, tributylammonium chloride, tributylbenzylammonium chloride, tetrapentylammonium chloride, tetrapentylammonium bromide, tetrahexylammonium chloride, benzyldimethyloctylammonium chloride, methyltrihexylammonium chloride, benzyldimethyloctadecanemmonium chloride, methyltridecanylammonium chloride, benzyltripropylammonium chloride, benzyltriethylammonium chloride, phenyltriethylammonium chloride, tetraethylammonium chloride or tetramethylammonium, substituted quaternary ammonium salts with groups selected from the group consisting of straight or branched chain Cl-18 alkyl group, a Cl-6 alkyl group phenyl and phenyl group, phosphonium salts substituted with alkylaryl groups, straight-chain or branched Cl-18 such as tetrabutylphosphonium chloride or substituted pyridinium salts with straight or branched chain Cl-8 alkyl group such as 1-dodecanylpyridinium chloride. The phase transfer catalysts can generally be used in the molar ratio to the compound (le) of between 0.1: 1 and 1: 1, preferably between 0.1: 1 and 0.5: 1.

The reaction of the compound (lc) with the compound (18) is by a method wherein the compound (lc) and carboxylic acid of the compound (18) are reacted with usual amide coupling generation reactions. The conditions for a known amide bond formation reaction can be broadly applied herein. Examples of such amide bond formation reaction include (a) mixed acid anhydride method, which is, a method for reacting the carboxylic acid (18) with alkyl haloformate to obtain a mixture of acid anhydride and reacting the acid anhydride with amine (lc), (b) the active ester method, which is, a method for converting the carboxylic acid (18) to an active ester such as p-nitrophenyl ester, N-hydroxy succinic acid imide ester or 1-hydroxybenzotriazole ester, or active amide such as benzoxazolin-2-thione, and then reacting this with amine (lc), (c) carbodiimide method, that is, a method for carrying out the reaction of condensation of the carboxylic acid (18) with amine (lc) in the presence of an activator such as dicyclohexylcarbodiimide, l- (3-dimethylaminopropyl) -3-ethylcarbodiimide (WSC) or carbonyldiimidazole, and (d) other methods include a method for converting acid carboxylic (18) in carboxylic anhydride by using a dehydrator such as acetic anhydride and reacting the carboxylic anhydride with amine (le), a method of reacting carboxylic acid ester (18) and lower alcohol with amine (le) at high pressure and elevated temperature, and a method for reacting the acid halide of the carboxylic acid (18), that is, carboxylic acid halide, with amine (le). The acid anhydride mixture used in (a) a method of mixing the acid anhydride as described above is obtained by a common Schotten-Baumann reaction. The acid anhydride mixture is reacted with amine (le) generally without being subject to isolation, so that the compound of the present invention represented by the general formula (lf) is produced. The reaction above Schotten-Baumann is carried out in the presence of a basic compound. The compounds that are commonly used by the Schotten-Baumann reaction can be used herein as basic compounds. Examples of such basic compounds include: organic bases such as triethylamine, trimethylamine, pyridine, dimethylaniline, N-ethyldiisopropylamine, dimethylaminopyridine, N-methylmorpholine, 1,5-diazabicyclo [4.3.0] noneno-5 (DBN), 1.8 -diazabicyclo [5.4.0] undecene-7 (DBU) or 1,4-diazabicyclo [2.2.2] octane (DABCO); the inorganic bases include carbonates such as sodium carbonate, potassium carbonate, sodium acid carbonate or potassium acid carbonate, metal hydroxides such as sodium hydroxide, potassium hydroxide or calcium hydroxide, potassium hydride, sodium hydride, potassium, sodium, sodium amide, and alcoholate metals such as sodium methylate or sodium ethylate. The reaction is carried out generally at -20 ° C to 100 ° C, and preferably at 0 ° C to 50 ° C. The reaction time is generally 5 minutes up to 10 hours, and preferably 5 minutes up to 2 hours. The reaction of the obtained mixture of acid anhydride with amine (le) is generally carried out at -20 ° C to 150 ° C, and preferably at 10 ° C to 50 ° C. The reaction time is generally 5 minutes up to 10 hours, and preferably 5 minutes up to 5 hours. The mixed acid anhydride method is generally carried out in a solvent. Any solvent that is commonly used by the mixed acid anhydride method can be used herein. Examples of such a solvent include halogenated hydrocarbons such as chloroform, dichloromethane, dichloroethane or carbon tetrachloride, aromatic hydrocarbons such as benzene, toluene or xylene, ethers such as diethyl ether, diisopropyl ether, tetrahydrofuran or dimethoxyethane, esters such as methyl acetate, ethyl acetate or isopropyl acetate, polar aprotic solvents such as N, N-dimethylacetamide, N, N-dimethylformamide, dimethylsulfoxide or hexamethylphosphoric acid triamide, and mixed solvents thereof. Examples of alkyl haloformate used by the mixed acid anhydride method include methyl chloroformate, methyl bromoformate, ethyl chloroformate, ethyl bromoformate, and isobutyl chloroformate. The molar ratio between the carboxylic acid (18), alkyl haloformate and amine (le) may generally be equal to 1: 1. Each of alkyl haloformate and carboxylic acid (18) can also be used for the amine (le) with the molar range between 1: 1 and 1.5: 1. The above method (c) involves the condensation reaction in the presence of the above activator which is carried out in an appropriate solvent in the presence or absence of a basic compound. As a solvent and a basic compound used herein, any solvent used in the carboxylic acid halide reaction with amine (lc) described above in (d) other methods can be used. The molar ratio of the activator to the compound (lc) can be at least equal to 1: 1, and preferably between 1: 1 and 5: 1. When WSC is used as an activator, the reaction advantageously proceeds if the 1-hydroxybenzotriazole is added in the reaction system.

The reaction is carried out generally at -20 ° C to 180 ° C, and preferably at 0 ° C to 150 ° C. The reaction time is generally 5 minutes to 90 hours. When the method which reacts the halide of the carboxylic acid acid with amine (le) is adapted from (d) other methods described above, the reaction is carried out in the presence of a basic compound in an appropriate solvent. Known basic compounds can be widely used herein. For example, any basic compound used in the Schotten-Baumann reaction above can be used. Examples of the solvent used may include alcohols such as methanol, ethanol, isopropanol, propanol, butanol, 3-methoxy-1-butanol, ethyl cellosolve or methyl cellosolve, acetonitrile, pyridine, acetone, water, as well as solvents used for the method of mixed acid anhydride from above. The molar ratio of amine (le) to the carboxylic acid halide is not particularly limited, but it can be appropriately selected from a wide range. The molar ratio of these compounds can generally be at least equal to 1: 1, and preferably between 1: 1 and 1: 5.

The reaction is generally carried out at -20 ° C to 180 ° C, and preferably at 0 ° C to 150 ° C. The reaction time is generally 5 minutes to 50 hours. The above amide bond formation reaction can also be carried out by reacting the carboxylic acid (18) with amine (lc) in the presence of a phosphorus condensing agent such as diphenylphosphinic chloride, phenyl-N-phenyl phosphoramide chloridate , diethyl chlorophosphate, diethyl cyanophosphate, diphenyl phosphate azide, or bis (2-oxo-3-oxazolidinyl) fofinic chloride. This reaction is carried out in the presence of a solvent and a basic compound which is used by the above method which reacts the carboxylic acid halide with amine (lc), generally at -20 ° C to 150 ° C, and preferably from 0 ° C to 100 ° C. The reaction time is generally 5 minutes up to 30 hours. Each condensing agent and carboxylic acid (18) is used to the amine (1c) at a molar ratio of at least equal to 1: 1, and preferably between 1: 1 and 2: 1. The reaction of the compound (lc) with the compound (19) can be carried out under the same conditions by the reaction of the compound (15) with the compound (16) or (17) represented by the reaction scheme 9 above.

Reaction scheme 11 (wherein R1A, X, n, m, W, R7a, R9, R10 and I are the same as above R6b represents an alkoxycarbonyl Cl-6 group The dotted line in the piperidine ring represents a bond which may be a bond double When the dotted line is a double bond, a group R6b, COOH or -CON R9R10 must be replaced.).

The compound (21) is produced by hydrolyzing the compound (20). The hydrolysis reaction is conducted in an appropriate solvent or without a solvent in the presence of an acid or basic compound. The solvent used may include, for example, water, lower alcohols such as methanol, ethanol, isopropanol or tert-butanol, ketones such as acetone or methylethyl ketone, ethers such as diethyl ether, dioxane, tetrahydrofuran, monoglyme or diglyme, aliphatic acids such as acetic acid or formic acid, esters such as ethyl acetate or methyl acetate, halogenated hydrocarbons such as chloroform, dichloromethane, dichloroethane or carbon tetrachloride, dimethyl sulfoxide, N, N-dimethylformamide, hexamethylphosphoric triamide or mixed solvents thereof. The acid may include, for example, mineral acids such as hydrochloric acid, sulfuric acid or hydrobromic acid, organic acids such as formic acid, acetic acid, trifluoroacetic acid, or sulfonic acids such as p-toluenesulfonic acid. The basic compound may include, for example, carbonates such as sodium carbonate, potassium carbonate, sodium acid carbonate or potassium acid carbonate, metal hydroxides such as sodium hydroxide, potassium hydroxide, calcium hydroxide or hydroxide lithium, or similar.

The acid or basic compound is used in molar ratio to compound (20) of at least 1: 1, and preferably between 1: 1 and 10: 1, or it can be used in a large excess as a reaction solvent. The reaction generally proceeds at about 0-200 ° C, preferably around 0-150 ° C and is generally completed around 10 minutes up to 30 hours. After the hydrolysis treatment described above, an additional treatment may be carried out in about 1-30 minutes usually at 0-100 ° C, preferably at room temperature to about 70 ° C in an appropriate solvent in the presence of a basic compound to complete the reaction. A solvent and basic compound used herein may use any solvent and basic compound which is used in the method wherein the halide of the carboxylic acid is reacted with the amine (le) of the method (d) between the reactions of the compound ( lc) with the compound (18) in the reaction scheme described above. The reaction of the compound (21) with the compound (22) is carried out under the reaction conditions similar to those of the reaction of the compound (le) with the compound (18) in the reaction scheme 10 described above. The quantity of the carboxylic acid (18) is based on the amine (lc) in the reaction scheme described above, while the amount of the amine (22) is based on the carboxylic acid (18) in the present reaction.

Reaction scheme 12 ¥ (23) (wherein R1A, n, X, m, W, o, X2, R4 and R5 are the same as above.) The reaction of a compound (li) with a compound (23) is carried out under the reaction conditions similar to those of the reaction of the compound (le) with the compound (17) in the reaction scheme described above 10.

Diagram of reaction 13 (wherein R1A, n, R18, X, m, W, or, R4 and X2 are the same as above.) R6aa represents an alkoxycarbonyl group Cl-6. R6bb represents: a Cl-6 alkyl group; phenyl group (which can be substituted with at least one of the groups selected from the group consisting of an alkylene dioxy Cl-4 group, cyano group, nitro group, amino group which can have a Cl-6 alkyl group as a substituent, sulfonyl group substituted with amino which can have a Cl-6 alkyl group as a substituent, alkoxycarbonyl Cl-6 group, alkylthio Cl-6 group, phenoxy group, phenyl C 1-6 alkoxy group, pyrrolidinyl group (which can be substituted with at least one group oxo in the pyrrolidine ring), imidazolyl group, isooxazolyl group, oxazolyl group, Cl-6 alkyl group phenyl, phenyl group, Cl-6 alkyl group, which can be a Cl-6 alkyl group as a substituent, alkoxy Cl group -6-pyrrolidinyl, halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl ring); alkoxycarbonyl Cl-6 phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-6 alkyl group with halogen and substituted or unsubstituted Cl-6 alkoxy group with halogen in the phenyl ring); alkyl group Cl-6 benzofuryl (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-6 alkyl group with halogen and substituted or unsubstituted Cl-6 alkoxy group with halogen in the benzofuran ring); C2-6 alkenyl benzofuryl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-6 alkyl group with halogen and substituted or unsubstituted Cl-6 alkoxy group with halogen in the benzofuran ring); alkyl group Cl-6 phenoxy (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-6 alkyl group with halogen and substituted or unsubstituted Cl-6 alkoxy group with halogen in the phenyl ring); alkyl Cl-6 thiazolyl group (which can be substituted with at least one phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted by halogen on the phenyl ring) on the thiazole ring); Cl-6 alkyl group phenyl (which can be substituted with at least one phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted by halogen on the phenyl ring), halogen atom, Cl-6 alkyl group substituted or unsubstituted by halogen and Cl-6 alkoxy group substituted or unsubstituted by halogen on the ring of phenyl); alkyl group Cl-6 pyridyl (which can be substituted with at least one phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted by halogen on the phenyl ring) on the pyridine ring); alkoxycarbonyl group Cl-6; benzothienyl group; alkyl group Cl-6 benzothienyl (which can be substituted with at least one halogen atom in the benzothiophene ring); alkyl Cl-6 indolyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-β alkyl group with halogen and substituted or unsubstituted Cl-6 alkoxy group with halogen in the indole ring); 4H-1, 3-benzodioxinyl group (wherein, in the 4H-1, 3-benzodioxine ring, at least one halogen atom can be substituted); naphthyl group; quinolyl group; benzothiazolyl group (which can be substituted with at least one Cl-6 alkyl group in the benzothiazole ring); 2,3-dihydro-lH-indenyl group (which can be substituted with at least one oxo group in the 2,3-dihydro-lH-indan ring); 9H-fluorenyl group or C2-6 alkenyl group phenyl (which may be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen, and Cl-alkoxy group) 6 substituted or unsubstituted with halogen in the phenyl ring). R6c represents a benzoyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl ring), halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl ring). R6d represents: a hydrogen atom; phenyl group (which may be substituted with at least one of the groups selected from a phenyl group (which may be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted C1-6 alkyl group) substituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl ring), a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl ring); alkyl group Cl-6 benzofuryl (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-6 alkyl group with halogen and substituted or unsubstituted Cl-6 alkoxy group with halogen in the benzofuran ring); benzofuryl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the benzofuran ring); alkyl group Cl-6 phenoxy (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-6 alkyl group with halogen and substituted or unsubstituted Cl-6 alkoxy group with halogen in the phenyl ring); alkyl Cl-6 thiazolyl group (which can be substituted with at least one phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted by halogen on the phenyl ring) on the thiazole ring); thiazolyl group (which can be substituted with at least one phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and alkoxy group) Cl-6 substituted or unsubstituted with halogen in the phenyl ring) in the thiazole ring); alkyl Cl-6 phenyl group (which can be substituted with at least one of the groups selected from a phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-alkyl group) 6 substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl ring), halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or not substituted with halogen in the phenyl ring); alkyl group Cl-6 pyridyl (which can be substituted with at least one phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted by halogen on the phenyl ring) on the pyridine ring); alkyl Cl-6 benzothienyl group (at least one halogen atom can be substituted on the benzothiophene ring); alkyl group Cl-6 indolyl (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, substituted or unsubstituted Cl-6 alkyl group with halogen and substituted or unsubstituted Cl-6 alkoxy group with halogen in the indole ring); pyridyl group (which can be substituted with at least one phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and alkoxy group) Cl-6 substituted or unsubstituted with halogen in the phenyl ring) in the pyridine ring); benzothienyl group (at least one halogen atom can be substituted in the benzothiophene ring); or indolyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the ring of indole).

R58 represents a phenyl group (which can be substituted with at least one of the groups selected from the group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl ring). The total number of carbons of the group -CHR18R6d in the general formula (lo) should not exceed 6. The reaction to carry from a compound (lk) to a compound (11) is carried out under the reaction conditions similar to those of the reaction to be carried from the compound (20) to the compound (21) in the reaction scheme described above 11. A reaction of the compound (11) with a compound (24) is carried out under the reaction conditions similar to those of the reaction of the compound (le) with the compound (17) in the reaction scheme described above 10. A reaction of the compound (11) with a compound (25) is carried out under the reaction conditions similar to those of the reaction of the compound (lc) with the compound (18) in the reaction scheme described above 10. A reaction of the compound (11) with a compound (26) is carried out under the reaction conditions similar to those of the reaction of the compound (le) with the compound (16 ) in the reaction scheme described above 10. A reaction of the compound (11) with a compound (27) is carried out under the reaction conditions similar to those of the reaction of the compound (lc) with the compound (19) in the reaction scheme described above 10. Reaction scheme 14 Rdf0H (26) (wherein R1A, n, X, m, W, o and R4 are the same as above.) R6f represents an alkyl group Cl-6 or alkyl group Cl-6 phenyl (which can be substituted with at least one of the groups selected from group consisting of a halogen atom, Cl-6 alkyl group substituted or unsubstituted with halogen and Cl-6 alkoxy group substituted or unsubstituted with halogen in the phenyl ring).) The reaction of a compound (Iq) with the compound (26) is conducted in an appropriate solvent in the presence of a condensing agent.

The solvents used herein may use any solvent which is used in the method wherein the carboxylic acid halide is reacted with the amine (lc) of the other methods (d) of the reactions of the compound (lc) with the compound (18) in the reaction scheme described above 10. A condensing agent may include, for example, N, N'-carbonyldiimidazole or the like. The molar ratio of the compound (26) and the condensing agent uses the compound (Iq) by at least, preferably between about 1: 1 and 2: 1. The reaction is carried out generally at 0-150 ° C, preferably around 0-100 ° C and is completed around 1-30 hours. Reaction scheme 15 (wherein R1A, n, X, m, W, or, R9 and R10 are the same as above.) A reaction of the compound (27) with a compound (28) is carried out under similar reaction conditions to those of the reaction of the compound (lc) with the compound (16) in the reaction scheme described above 10. Reaction scheme 16 R * e0H (29) (where R1A, n, X, m, W, o, R, 7 / aa and R, 1J "0uaa are the same as above.) Two Ws in the general formulas (lt) - (lv) can be the same or R9f represents an alkoxycarbonyl Cl-6 group The dotted line in the piperidine ring represents a bond that can be a double bond When the dotted line is a double bond, a group - (W) or NR9fR10, group - (W ) oNHR10a or group - (W) or NR10a (COOR9g) must be replaced R9g represents an alkyl group Cl-6 or alkyl group Cl-6 phenyl (which can be substituted with at least one of the groups selected from the group consisting of halogen atom, Cl-6 alkyl group substituted or unsubstituted by halogen and Cl-6 alkoxy group substituted or unsubstituted by halogen on the phenyl ring). The reaction to carry the compound (It) to the compound (lu) is carried out under reaction conditions similar to those of the reaction to bring from the compound (20) to the compound (21) in the reaction scheme described above 11. A reaction of the compound (lu) with the compound (29) is carried out under reaction conditions similar to those of the reaction of the compound (lq) with the compound (26) in the reaction scheme described above 14. starting compound (14) in reaction scheme 9 and the starting compound (20) in the reaction scheme 11 are new compounds. These compounds are easily manufactured, for example, in consequence to reaction schemes 1 to 3 above using the corresponding starting materials. The compounds (final compounds) represented by the general formula (1) of the present invention and intermediates obtained in the reaction scheme described above include stereoisomers and optical isomers. Each objective compound obtained in the reaction scheme described above can be isolated and purified from the reaction mixture, for example, by crude reaction products isolated by isolation operations such as filtration, concentration and extraction after cooling, followed by purification operations. such as column chromatography and recrystallization. The compound of the present invention includes a pharmaceutically acceptable salt of the compounds of the formula (1) . Examples of such salts include inorganic salts such as hydrochloride, hydrobromide, nitrate, sulfate or phosphate, and organic salts such as methanesulfonate, p-toluensufonato, acetate, citrate, tartrate, maleate, fumarate, malate or lactate. Next, a medical preparation contains the compound of the present invention as an active ingredient is explained. The above medical preparation is obtained by preparing the compound of the present invention in the form of a common medical preparation. This is prepared using commonly used diluents or excipients such as fillers, blowing agents, binders, wetting agents, disintegrators, surfactants or lubricants.

Such a medical preparation can be selected from various forms, depending on the therapeutic purposes. Typically examples of a preparation include tablets, pills, powders, liquids, suspensions, emulsions, granules, capsules, suppositories, and injections (liquid, suspension, etc.). Known carriers can be widely used to make the medical preparation in the form of a tablet. . Examples of such carriers include excipients such as lactose, sucrose, sodium chloride, glucose, urea, starch, calcium carbonate, kaolin or crystalline cellulose; binders such as water, ethanol, propanol, simple syrup, glucose solution, starch solution, gelatin solution, carboxymethyl cellulose, sealer, methyl cellulose, potassium phosphate or polyvinyl pyrrolidone; disintegrators such as dry starch, sodium alginate, agar powder, laminaran powder, sodium hydrogencarbonate, calcium carbonate, fatty acid ester of polyoxyethylene sorbitan, sodium lauryl sulfate, monoglycerol stearate, starch or lactose; disintegration controllers such as sucrose, stearin, cocoa butter or hydrogenated oil; enhancers absorption such as quaternary ammonium base or sodium lauryl sulfate, humectants such as glycerin or starch, adsorbents such as starch, lactose, kaolin, bentonite or colloidal silica, and lubricantas such as purified talc, stearate, boric acid powder or polyethylene glycol. However, such tablets may be prepared as tablets with tablet common coated, such as a tablet coated with sugar coated tablet, gelatin tablet with enteric coating, film-coated tablet, tablet with double coated or coated tablet multilayer. Known carriers can be widely used to make the medical preparation in a pill form. Examples of such carriers include excipients such as glucose, lactose, starch, cacao butter, hydrogenated vegetable oil, kaolin or talca, linkers such as gum arabic powder, tragacanth powder, gelatin or ethanol, and disintegrators such as laminaran or agar . Known carriers can be widely used to make the medical preparation in suppository form. Examples of such carriers include polyethylene glycol, cocoa butter, higher alcohol, higher alcohol esters, gelatin, and semisynthetic glyceride. In a case where the medical preparation is prepared as an injection such as a liquid, emulsion or suspension, these solutions are preferably sterilized and prepared to render the blood isotonic. Known diluents can be widely used to make the medical preparation in the form of a liquid, emulsion or suspension. Examples of such a diluent include water, ethanol, propylene glycol, ethoxylated isostearyl alcohol, polyoxylated isostearyl alcohol and polyoxyethylene sorbitan fatty acid ester. However, in the case of using the medical preparation as an injection, a certain amount of common salts, glucose or glycerin which is sufficient to prepare an isotonic solution can be added to the medical preparation. Otherwise, a common solubilizing agent, buffer, softening agent or the like can also be added for medical preparation. In addition, a coloring agent, preservative, perfume, flavoring, softening agent or other pharmaceuticals may also be added thereto, if necessary. The amount of the compound of the present invention contains in the medical preparation that is not particularly limited, but may be appropriately selected from a wide range. Generally, 1 to 70% by weight of the compound of the present invention is preferably contained in the medical preparation. The method for administering the medical preparation of the present invention is not particularly limited. This is administered depending on various forms of preparation, patient's age, sex, disease conditions or other conditions. For example, where the medical preparation adopts a tablet, pill, liquid, suspension, emulsion, granule or capsule form, this is administered orally. In the case of an injection, this may be administered intravenously, simply or in combination with a commonly auxiliary fluid such as glucose or amino acid. However, if necessary, this can simply be administered intramuscularly, intradermally, subcutaneously or intraperitoneally. In the case of a suppository, this can be administered intrarectally. The dose of the above medical preparation can be appropriately selected depending on the use, age of the patient, level of disease or other conditions. Generally from 0.01 to 100 mg, preferably 0.1 to 50 mg per kg of the body weight of the medical preparation is administered once or divided into several times per day. Since the above dose is altered depending on several conditions, the lower dose than the above range may be sufficient in some cases, or the higher dose than the above range may be required in other cases. The compound of the present invention has a specific effect against mycobacterium tuberculosis such as fast-acid bacteria (Mycobacterium, fasting bacteria, atypical acid). The compound of the present invention has an excellent effect with multidrug-resistant Mycobacterium tuberculosis. The compound of the present invention has an antimicrobial action against anaerobic bacteria.

The compound of the present invention not only shows the activities described above in vitro, but also expresses the above activities in oral administration. The compound of the present invention does not induce diarrhea, which is induced by known antimicrobial agents having a broad spectrum for the common bacterium such as Gram-positive bacteria or Gram-negative bacteria. In addition, this has fewer adverse reactions than existing agents. Consequently, this can be a medical preparation, which can be administered for a long time. The compound of the present invention can be distributed in the tissues of the lung, the upper organ that is infected by acid-assisting bacteria and these properties such as sustained efficacy or excellent safety. Consequently, a superior therapeutic effect can be expected from the compound. When compared to existing antitubercular agents, the compound of the present invention shows a strong bactericidal action even towards cytozoic bacteria such as mycobacterium tuberculosis present in a human macrophage. As a result, the reduction of the rate of occurrence of tuberculosis and the performance of short-term chemotherapy is allowed. This therefore expects that the compound of the present invention is also used as a superior preventive agent administered by an infection mixed with HIV and tuberculosis, which is conceived to be a serious problem. EXAMPLES Formulation Examples, Text Examples, Examples Reference and Examples will be described below. Formulation Example 1 100 g of a compound of the invention, 40 g of Avicel (trade name, manufactured by Asahi Kasei Corporation), 30 g of corn starch and 2 g of magnesium stearate were mixed and ground and then formed into tablets with a sugar-coated plate of RIO mm. A film coating agent containing 10 g of TC-5 (trade name, hydroxypropyl methylcellulose, manufactured by Shin-Etsu Chemical Co., Ltd.), 3 g of polyethylene glycol 6000, 40 g of castor oil and an amount Suitable ethanol is used to coat the obtained tablets, providing a film-coated tablet having the composition described above. Reference Example 1 Preparation of 1- (4- (tetrahydropyran-2-yloxy) phenyl) -4- (N- (4-chlorophenyl) -N-methylamino) piperidine 4- (N- (4-chlorophenyl) -N -methylamino) -piperidine (2.52 g, 11.22 mmol), 2- (4-bromophenoxy) tetrahydropyran (2.89 g, 11.22 mmol), palladium acetate (50 mg, 0.22 mmol), (S) - (-) -2, 2-bis (diphenylphosphino) -1, 1-binaphthyl (BINAP) (212 mg, 0.34 mmol) and sodium tert-butoxy (1.51 g, 15.71 mmol) were refluxed with heating in toluene (30 ml) under a Nitrogen atmosphere for 3 hours. Ethyl acetate and water were added to the reaction solution and stirred, then the resulting precipitate was removed by filtration through Celite, then the filtrate was extracted with ethyl acetate. The organic phase was washed with saturated brine, dried over magnesium sulfate, and then filtered. After the resulting filtrate was concentrated under reduced pressure, the residue was purified by silica gel column chromatography (n-hexane / ethyl acetate = 20/1) to provide 1- (4- (tetrahydropyran-2-yloxy) ) phenyl) -4- (N- (4-chlorophenyl) -N-methylamino) piperidine (1.33 g, yield 30%) as a light yellow powder. A-NMR (CDC13) dppm: 1.50 - 2.04 (10H, m), 2.68 - 2.80 (2H, m), 2.78 (3H, s), 3.50 - 3.70 (4H, m), 3.85 - 4.03 (H, m) , 5.31 (ÍH, t, J = 5.7 Hz), 6.72 (2H, d, J = 9.1 Hz), 6.90 (2H, d, J = 9.2 Hz), 6.98 (2H, d, J = 9.2 Hz), 7.17 (2H, d, J = 9.1 Hz). Reference Example 2 Preparation of 4- (4- (N- (4-chlorophenyl) -N-methylamino) piperidin-1-yl) phenol 1- (4- (Tetrahydropyran-2-yloxy) phenyl) -4- ( N- (4-chlorophenyl) -N-methylamino) piperidine (1.33 g, 3.32 mmol) was suspended in ethanol (80 ml). To this mix, pyridinium p-toluenesulfonate (0.25 g, 1 mmol) was added and then stirred at 70 ° C for 8 hours. The ethanol was removed under reduced pressure, then to this residue, methylene chloride and a saturated aqueous sodium hydrogen carbonate solution were added and stirred. This was extracted with methylene chloride, dried over magnesium sulfate and then filtered. After the resulting filtrate was concentrated under reduced pressure, methyl chloride and n-hexane were added to the residue and the resulting precipitate was filtered to provide 4- (4- (N- (4-chlorophenyl) -N-methylamino) piperidin-1-yl) phenol (922.5 mg, 88% yield) as a light pink powder. A-NMR (CDC13) dppm: 1.79 - 2.04 (4H, m), 2.67 - 2.79 (2H, m), 2.79 (3H, s), 3.56 - 3.68 (2H, m), 4.48 (HH, s), 6.69 - 6.80 (4H, m), 6.85 - 6.92 (2H, m), 7.14 - 7.21 (2H, m). The following compounds were prepared similarly to Reference Example 1 and 2. In the following table, Ph means a phenyl group or phenylene group. Reference Example 3 (4-Chlorophenyl) - (4-hydroxyphenyl) methanone O-methyloxime MS: 261 (M +). Reference Example 4 (4-Hydroxyphenyl) - (4-trifluoromethylphenyl) methanone O-methyloxime MS: 295 (M +).

[Table 1 ] reference example R1 'H NMR or EM? NMR (CDCI3) d 1.79 -1.89 (2H, m), 2.01 -2.08 (2H, m), 2.77-2.87 (2H, m), 3.33-3.41 (2H, m) , 3.53-3.56 (2H, m), 4.59 (2H, s), -CH, CfiHc 4.63 (1 H, brs), 6.74 (2H, d, J = 9.0Hz), 6.87 (2H, d, J = 9.0 Hz), 7.27-7.36 (5H, m). 'H NMR (CDCl 3) d 1.76-1.90 (2H, m), 2.00-2.10 (2H, m), 2.84 (2H, m), 3.33-3.42 (2H, m), 3.51-3.60 (1H, m), 4.53 (1 H, brs), 4.63 (2H, s), 6.74 (2H, 4-CF3OPhCH, d, J = 9.0Hz), 6.87 (2H, d, J = 9.0Hz), 7.48 (2H, d, J = 8.1Hz), 7.60 (2H, d, J = 8.2Hz). iHRMN (CDCI3) d 1.71 - 1.93 (2H, m), 1.95-2.15 (2H, m), 2.71-2.93 (2H, m), 3.26-3.46 (2H, m), 3.46-3.63 (1H, m), 4.50 (1 H, s), 4.57 (2H, s), 6.74 (2H, 4-CF, PhCH, -d, J = 9.0Hz), 6.87 (2H, d, J = 8.9Hz), 7.19 (2H, d, J = 8.5Hz), 7.39 (2H, d, J = 8.4Hz) . ? NMR (CDCl 3) d 1.69-1.9K2H, m), 1.95-2.14 (2H, m), 2.72-2.90 (2H, m), 3.26-3.44 (2H, m), 3.44-3.63 (1H, m), 4.46 (1 H.ampiio | s), 8 4-CIPhCH, 4.54 (2H, s), 6.74 (2H, d, J = 9.0Hz), 6.87 (2H, dt J = 9.0Hz), 7.20-7.33 (4H, m). • H NMR (CDCI3) d 1.71 - 1.93 (2H, m), 1.93-2.18 (2H, m), 2.70-2.93 (2H, m), 3.22-3.45 (2H, m), 3.45-3.65 (1 H, m), 4.52 (2H, s), 3,4-CI, PhCH, - 4.85 (1 H, brs), 6.73 (2H, d, J = 9.0Hz), 6.82 (2H, d, J = 9.0 Hz), 7.19 (1 H, dd, J = 8.2 Hz, 2.0 Hz), 7.41 (1 H, d, J = 8.2 Hz), 7.46 (1 H, d, J = 1.9 Hz). 10 4-CF3OPh (CH2) 2- E: 381 (M +) 11 4-GF3OPhCH = CHCH2-EM :: 393 (M +) 12 4-CF3OPh (CH2) 3- ¿M :: 395 (+) [Table 2] Reference example "-; ... R2 RMN OR EM? RM (GDCIJ) d 1.79-2.0 ^ 4K.m), 2.β7-2r792H. M, 13 ~ GiPh ~ "OHa ZM ß, 3,5S-3-? DC2Ht m), 4.4BUH, s? ß.ßS-ß.ßO4H, m), ß.eS-ßd2CZH, MX 7.14-72K2H. MX 1if NMR (CDCIj) 51.5 &- 1.72 (2 », mX Z \ fr tfí & tí, m), 2.77- &8SÍZH, mX M4-2.§nm, mi 3.92Í? H ,, á, J *? 4rlz? 14 4-CF-, Pfr 4.86 (1 H s? 6.53-BJ3 (2H.) .6.72-6.79C2H, m). S.85-6.92 (2tf, m) r 7.3S ~ 7.42 (2H, rpX SH NMR ÍCDCÜ 51.26-2.48 <3Hr m), 2J1-2, SO (SH, m > fifteen - . 15 - € H ^? 3.36-3.5SÍ2H, m \ Mñ (r a), B.65- & YES2H, mX 8.79-6.91 (H, mX 7J5-7.43 (5H.m? »H RMN IQ GQ 1. 1.34-1, 7 (2H. RoX? .98-2.11Í2H, ro? W -ClP C - -H 2 I-2 4C3H, mj, 3, tS-3 7ím, 2HX 3.82 (211, ßX ß? ß-ß / WZH, mX 6.79-6 2Í2H, m 7.09-7.4í { 4H, itiX jH NMR { GD € Ij) 81.34-1 JB € (2H. M.}., 1.89-2.1? (2Hr m), 17 aA-C? HCür -H z -zm, mi 3? - &54í2H, mX am & a, «x ßJSs-waeH, mX 6, &0-6.? > X2H. ), 7.1f-7.23 < 1 HOUR. i JafiOHz), 1.33-7.42 (1 H, d J = B.2Hí &7.43-7.50Í1H. d.J = Z0H¡-X SH NMR {CDCPj tS 1.40 - 1 8 (2Hr mX t .87 -2.12 (2K, m), 2, §0-2, SG (3H, m? 3.3fl-3.5S {2¡i pó, 3.92 (2HP s), SJ6-6.B0Í2H, IS -CFaPhCHs- -H mX 6¿f ß.93C2H, mi). ? .47 (2H, or, < J = S, 2Har 7.58C2H, AJ = 8.1Hz). 5K NMR < CDO,) * 1.45- 1.lQ (mt mX 1.ßß-2.16 (2Ht mX £ 4ß-2¿33H, m), 3¿3-3¿7 (2H.X 48B &H, sX tJ, 82- &? s (gH, Í9 4 ~ GF3GPr, GHr -H mX e, 80-Í 3í2Hc mX 7.17C2H, d, JatMHzX '7 (2H, 4 J = 8.5Hz). SK NMR (GDOy 61.83-1.69Í2Ü), Z, 13-Z19CZH, m), 2.75-2.3S < 2íi ps 3.37-3.S1. { 3H,? I 3.63 (1 M "dr J = 7.86Hfe? 4-CH4OPl? - -H 4.4SC1H, s), ßw53-6.ß1 (2'l.mX 6.72-8.80Í2H.m), B, g @ -0. & 2Í2B, p »X 7, QT ~ 7.05 (2H, ra). ! H NMR (OOCIa) 3 1.52-1, ß8C2H, m), 2.13-2. tSCH roX 2.75-2.86Í2H, «iX 3.35-3.56 (4 ^ m), 4ß9 (1H, brsX 21 4-CIPfr -H 6.51 ~ 6.5 & {.2H r mX 6.7G-6.79 (2H, \ 8.85- 8 3 (2B.mX 7.10-7.1BÍ2H r mX 23 4-GHaOP - -CHj EM:; ggß¡M +) 24 4-GFsPrr-MS: 39tMM +) 25 4 ~ CFiP CKí- -GßH5 EM = 42"M + > 28 (CH ^ COCO- -HE: 29Z (NI *) 27 (GHs > $ COCO- -C_H_ EM :! 320CM * -) [Tabl] Example of or EM reference R1 NMR 28 -C8HS MS: 267 (M +) 1 H NMR (CDCl 3) d 1.48-1.63 (2H, m), 1.87-1.98 (3H, m), 29 4-CF3OPhO- 2.62-2.72 (2H, m), 3.51-3.57 (2H, m), 3.83 (2H, d, J = 5.88Hz), 4.50 (1H, brs), 6.73-6.78 (2H, m), 6.84-6.91 (4H, m), 7.12- 7.16 (2H, m). 1H RN (CDC! 3) d 1.36-1.90 (5H, m), 2.56-2.68 (2H, m), 30 4-CF3OPhCH20- 3.38 (2H, d, J = 6.31Hz), 3.44-3.53 (2H, m ), 4.51 (2H, s), '4.66 (1H, brs), 6.70-6.77 (2H, m), 6.83-6.89 (2H, m), 7.17- 7.21 (2H, m), 7.34-7.39 (2H, m). 31 4-CF3OPh- EIV1: 351 (M +) 'H NMR (CDCl3) d1.31 -1.86 (5H, m), 2.43-2.77 (4H, m), 32 4-CF3Ph- 3.34-3.58 (2H, m) , 4.57 (1 H, brs), 6.66-6.80 (2H, m), 6.80-6.92 (2H, m), 7.28 (2H, d, J = 7.7Hz), 7.55 (2H, d, J = 8.1Hz) . 33 4-CIPh-MS: 301 (M +) 34 3.4-CI2Ph-MS: 335 (M +) 1H RN (CDCy d 1.34-1.51 (2H, m), 1.68-1.90 (3H, m), 35 4- CIPhCH20- 2.56-2.67 (2H, m), 3.36 (2H, d, J = 6.36Hz), 3.46-3.52 (2H, m), 4.43 (1 H, s), 4.48 (2H, s), 6.71-6.78 (2H, m), 6.83-6.89 (2H, m), 7.27-7.34 (4H, m) .H NMR (CDCI3) d 1.37-1.54 (2H, m), 1.68-1.90 (3H, m), 2.57- 2.68 (2H, m), 3.39 (2H, d, J = 6.29Hz), 3.46-3.52 (2H, m), 36 4-CF3PhCH20- 4.57 (2H, s), 5.28 (1 H, s), 6.67- 6.74 (2H, m), 6.83-6.89 (2H, m), 7.43-7.47 (2H, m), 7.58-7.62 (2H, m) .1H NMR (CDC! 3) d 1.48-1.63 (2H, m) , 1.86-1.98 (3H, m), 37 4-CIPhO- 2.61-2.71 (2H, m), 3.51-3.56 {2H, m), 3.82 (2H, d, J = 5.95Hz), 4.49 (1 H, s), 6.73-6.91 (6H, m),? .19-7.25 (2H, m). 'H NMR (CDCI3) d1.38- 1.54 (2H, m? 1.64-1.79 (1 Hm), 1.89 (2H, d, J = 12.9Hz), 2.62 (2H, dt, J = 1.99, 11.98Hz), 3.11 (2H, t, J = 6.27Hz), 3.52 (2H, d, J = 11.98Hz), 4.00- 38 4-CF3PhNH- 4.18 (1H, brm), 4.46 (1H, brs), 4.39-4.55 (1H , brs), 6.60 (2H, d, J = 8.56Hz), 6.75 (2H, d, J = 8.89Hz), 6.87 (2H, d, J = 8.89Hz), 7.40 (2H, d, J = 8.56Hz) ) 1H NMR (CDCI3) d1.37-A57 <; 2H, m), 1.61 -1.77 (1H, m), 1.79-1.97 (2H, m), 2.52-2.70 (2H, m), 3.04 (2H, d, J = 6.70Hz), 39 4-CIPhNH-3.51 (2H, d, J = 11.98Hz), 3.76-4.76 (2H, br), 6.48-6.58 (2H, m), 6.71-6.81 (2H, m), 6.83-6.92 (2H, m), 7.08-7.17 (2H, m) 1HRIVIN (CDCI3) 61.37-1.81 (4H, m), 1.90 (2H, d, J = 6.20Hz), 2.63 (2H, t, -M11.68Hz), 3.05 ( 2H, d, J = 6.66Hz), 3.52 (2H, d, 40 4-CF3OPhNH- J = 11.99Hz), 3.69-4.07 (1H, br), 4.18-4.74 (1H, br), 6.49-6.63 (2H , m), 6.67-6.82 (2H, m), 6.87 (2H, d, J = 8.64Hz), 7.03 (2H, d, J = 8.64Hz) 1H NMR (DMSO) d 1.35-1.45 (2H, m) , 1.68-1.80 (3H, m), 2.46-2.56 (2H, m), 3.40-3.46 (2H, m), 4.00 (2H, d, J = 5.90Hz), 41 4-CJP NHC02-6.66-6.65 ( 2H, m), 6.67-6.81 (2H, m), 7.31-7.35 (2H, m), 7.45-7.51 (2H, m). 8.78 (1 H, s), 9.79 (1 H, s).

[Table 4] Example of referential R1 2 NMR? NMR (CDGIJ) < 53.58C1H. brs), 3J8CZH, d, J = 5.7HzX 4.24Í1H, 42 -H 4-GF3GPhCH = GHGHsr br? .31C1H, A, J = 15.9, 5.7Hz} , S.57-8 £. { 3H, X 6.β9- &73 (2H.m). 7.13-7.16C2H, mX 7.3SA3SÍ2M, m [Table 5] Reference example 111 RL NMR? RM CCDC) d 1.21 - 1.3SC2H n .1.46 &H. sX 1.94-2.Q8Í2H. mX Z7M.0OC2H, brmX 3.08-3, Míri Four. Five - . 45 -H br), 3L27-3.3SY1 * H. l «X *" J37-4, Z2 {2R brX 4.2S- 8 (Ht b R5D- & 58 & amp. 1 mX 6, S6-8.75C2H. m) SH NMR & 1.44- 1 9Í2H, ml 2? W.?, J = 11.54Hz). Z.92-3-.03Í2H, mX 3,? 4-3,32í1H, brsX 'H NMR (GPQL,) ff 1.75-1.83Í4H, bf¿ > , "CHa Z - £. (< m 3.37-3, §S" B, 3 9-3.82Í2H, ml 4.36 (1 H, áX 6.63.-6 6H,), 7.15-7.?3И ? B, m) H NMR (COGIs) 51.72-1.9K4H. m 2.72Í3B, sX [Table 6] Reference example R1 NMR 1 H NMR (CDCl 3) d 3 SC 2 H, a), 4 6 (1 H, s) t 52 4-CF 3 Pb-6 J 5-6.79 2 2 H, ra), 7.01-7. T 6 2 2 H, m), 7.2- 7.Z9 (2H, m? 7.51-7.54C2H, m 53 4-ClPh-1H NMR (GDCy 53.87C3H, br? X 6.74-6.78I2H, mX 7.01-7.CNf (2H, mX 7.07-7.1 OtOH, tn). 7.22-7.26 (2 m).

[Table 7] Example of 1H RMW (CDOTÍ) < 5 1.B &-2.G2Í2B, num, 2J97-2 8? 2B. m > , - you f ~ ^^ __ -O & rjg.4. 21H. n? &4t-3.59 (ZH.mj¡, 44t-4.50HH,. -F .74J1H s), $ M-e m, m¡. $ .n ~? mm, F F 7.12-7.17CZH.m 7.40-7.4SÍ4H ,? > ). 7. 53 ~ 7.7 £ ífiH, ni), 8.53 (1 you, s). eo S 4.73 (1 Hs>, @ LBB- € .93 { 2H, «i), 7, l7-7.Zgí? H.p? ?? 3-7.5S &MI. m), [Table 8] [Table 9] [Table 10] Example of Rl R2 NMR reference 67 -H-CDC13; 1.37-1.66 (5H, m), CF3OPhCH20 (CH2) 2- 1.75-1.81 (2H, m), 2.55-2.65 (2H, m), 3.44-3.50 (2H, m), 3.55 (2H, t, J = 6.3Hz), 4.44 (lH, s), 4.50 (2H, s), 6.72-6.78 (2H, m), 6.83-6.89 (2H, m), 7.18-7.22 (2H, m), 7.35-7.39 (2H , m) 8 -H 4-FPhNH-CDC13; 1.51-1.66 (2H, m), 2.13-2.18 (2H, m), 2.74-2.85 (2H, m), 3.30-3.50 (4H, m), 4.50 (lH, s), 6.53-6.61 (2H, m ), 6.73-6.78 (2H, m), 6.85-6.94 (4H, m) 9 -H 4-CF3OPhNHCH2- CDC13; 7.03 (2H, d, J = 8.6Hz), 6.87 (2H, d, J = 8.6Hz ), 6.82-6.67 (2H, m), 6.63-6.49 (2H,), 4.74-4.18 (HI, br), 4.07-3.69 (1H, br), 3.53 (2H, d, J = 12.0Hz), 3.05 (2H, d, J = 6.7Hz), 2.63 (2H, t, J = 6.7Hz), 1.90 (2H, d, J = 12.4Hz), 1.81-1.37 (3H, m) Example of Rl R2 NMR reference 70 -H 4-ClPhNHCH2- CDC13; 7.17-7.08 (2H, m), 6.92-6.83 (2H, m), 6.81-6.71 (2H, m), 6.58-6.48 (2H,), 4.76-3.76 (2H, br ), 3.51 (2H, d, J = 12.0Hz), 3.04 (2H, d, J = 6.7Hz), 2.70-2.52 (2H, m), 1.88 (2H, d, J = 12.3Hz), 1.77- 1.61 (1H, m), 1.57-1.37 (2H,) 1 -H-3,5-Cl2PhNH-CDC13; 1.48-1.64 (2H, m), 2.05-2.19 (2H, m), 2.71-2.88 (2H, m), 3.21-3.48 (3H, m), 3.75 (1H, d, J = 8.0Hz), 4.71 ( ÍH, bs), 6.46 (2H, d, J = 1.8Hz) 2 -H 4-n-C3H7-PhNH-CDC13; 0.94 (3H, t, J = 7.3Hz), 1.45-1.71 (4H, m), 2.05-2.21 (2H, m.), 2.47 (2H, t, J = 7.3Hz), 2.64-2.83 (2H, m ), 3.29-3.52 (3H, m), 4.83 (ÍH, br), 6 [Table 11] [Table 12] [Table 14] [Table 15] Example of RL EM reference 95 409 (M +) 96 410 (M +) 97 408 (M +) 98 261 (M +) -Cl ^ 99 387 (M +) [Table 17] [Table 18] [Table 19] [Table 20] [Table 21] Example 1 Preparation of (R) -2-methyl-6-nitro-2- (2- (4- (4-trifluoromethoxybenzyl) -piperazin-1-yl) benzothiazol-6-yloxymethyl) -2,3-dihydroimidazo [2 , 1-b] oxazole The (R) -2-Chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole (51 mg, 0.23 mmol) and 6-hydroxy-2- (4 - (4-trifluoromethoxybenzyl) -piperazine-1-yl) -benzothiazole (80 mg, 0.20 mmol) were dissolved in DMF (5 ml). To this mixture, sodium hydride (10 mg, 0.25 mmol) was added and stirred at 60 ° C for 1.5 hours. After allowing it to stand at room temperature, water was added to the reaction solution and extracted with ethyl acetate. The combined organic layer was washed with water and saturated brine, then dried over magnesium sulfate. This was filtered and then the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (n-hexane: ethyl acetate = 1: 3-ethyl acetate) and recrystallized from ethanol to provide (R) -2-methyl-6-nitro-2 - (2- (4- (4-trifluoromethoxybenzyl) ~ piperazin-1-yl) benzothiazol-6-yloxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole (40 mg, yield 33%) as crystals of colorless powder. Melting point: 205.6-207.4 ° C. Example 2 Preparation of (R) -2-methyl-6-nitro-2- (2- (4- (4-trifluoromethoxyphenoxy) piperidin-1-yl) pyridine-5-oxy) methyl-2,3-dihydroimidazo [2, 1-b] oxazole 5-Hydroxy-2- (4- (4-trifluoromethoxy) -phenoxy) piperidin-1-yl) pyridine (0.67 g, 1. 9 mmol) and (R) - 2-Chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole (0.51 g, 2.4 mmol) was dissolved in CMF (6.7 mL). To this mixture, sodium hydride (91 mg, 2.3 mmol) was added and stirred at 50-55 ° C for 1 hour. Water was added to the reaction solution and extracted with methylene chloride. The organic layer was washed with saturated brine, dried over magnesium sulfate and then filtered under suction. The resulting filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (methylene chloride / ethyl acetate = 10/0, 9/1, 8/2), and further crystallized from methylene chloride / diisopropyl ether / ethyl acetate. ethyl to afford (R) -2-methyl-6-nitro-2- (2- (4- (4-trifluoromethoxyphenoxy) piperidin-1-yl) pyridine-5-oxy) methyl-2,3-dihydro-imidazo [ 2, 1-b] oxazole (0.30 g, 29% yield) as a light yellow powder. A-NMR (CDC13) dppm: 1.77 (3H, s), 1.80 - 1.94 (2H, m), 1.94 - 2.17 (2H, m), 3.21 - 3.44 (2H,), 3.67 - 3.89 (2H, m), 3.96 - 4.11 (2H, m), 4.19 (HH, d, J = 10.4 Hz), 4.36 - 4.59 (2H, m), 6.65 (HH, d, J = 9.2 Hz), 6.83 - 6.97 (2H, m) , 7.02 - 7.20 (3H, m), 7.56 (HH, s), 7.87 (HH, d, J = 3.0 Hz). The following compounds were prepared similarly to Example 2 described above. In the following table, Ph means a phenyl group or phenylene group. Example 3 (R) -2- (4- (4- (N- (4-chlorophenyl) -N-methylamino) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydro- imidazo [2, 1-b] oxazole Melting point: 173. 7-175. 1 C . Example 4 (R) -2-methyl-6-nitro-2- (4- (4- (4-trifluoromethoxybenzyl) piperidin-1-yl) phenoxymethyl) -2, 3-dihydroimidazo [2, 1-b] oxazole A-NMR (CDCl 3) dppm: 1.23-1.52 (2H,), 1.52-1.66 (3H, m), 1.66-1.89 (3H, m), 2.43-2.70 (4H, m), 3.50 (2H, d, J = 12.1 Hz), 3.91 - 4.09 (2H, m), 4.16 (HH, d, J = 10.1 Hz), 4.48 (HH, d, J = 10.2 Hz), 6. 66-6.81 (2H, m), 6.81-6.95 (2H, m), 7.05-7.23 (4H, m), 7. 54 (1H, s). Melting point: 210.9-212.4 ° C. [a] D = -9.0 ° (concentration: 1.0, CHC13). Example 5 (R) -2- (4- (4- (3,4-dichlorobenzyl) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole A-NMR (CDC13) dppm: 1.24-1.52 (2H, m), 1.52-1.64 (4H, m), 1.64-1.73 (1H,), 1. 73 - 1.87 (4H,), 2.38 - 2.68 (4H, m), 3.49 (2H, d, J = 12. 1 Hz), 3.91 - 4.09 (2H, m), 4.16 (1H, d, J = 10.2 Hz), 4. 49 (ÍH, d, J = 10.2 Hz), 6.67 - 6.81 (2H, m), 6.81 - 6.92 (2H, m), 6.94 - 7.07 (HH, m), 7.25 (HH, s), 7.35 (HH, d, J = 8.2 Hz), 7.55 (1H, s). Melting point: 180.0-181.2 ° C. [] D = -8.5 ° (concentration: 1.0, CHC13). Example 6 (R) -6-nitro-2- (4- (4- (4-trifluoromethoxybenzyloxymethyl) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole Melting point: 140.4-141.7 ° C.

Example 7 (R) -2-Methyl-6-nitro-2- (4- (4- (4-trifluoromethylbenzyloxymethyl) -piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole Melting point: 172.3-172.9 ° C. Example 8 (R) -2-Methyl-6-nitro-2- (4- (4- (3- (4-trifluoromethyphenyl) -2-propenyl) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [ 2, 1-b] oxazole Melting point: 199.7-202 ° C. Example 9 (R) -2-Methyl-6-nitro-2- (4- (4- (2- (4-trifluoromethoxyphenoxy) ethyl) piperazin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1 -b] oxazole Melting point: 194.8-195.6 ° C. Example 10 (R) -2- (4- (4- (N- (4-chlorophenyl) -N-ethylamino) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [ 2, 1-b] oxazole Melting point: 121.4-125 ° C. Example 11 (R) -2- (4- (4- (N-ethyl-N- (4-trifluoromethoxyphenyl) amino) piperidin-l-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole Melting point: 122.5-122.8 ° C.

Example 12 (R) -2- (4- (4- (N-ethyl-N- (4-trifluoromethylphenyl) -amino) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2, 3- dihydroimidazo [2, 1-b] oxazole Melting point: 105-108.5 ° C. Example 13 (R) -2- (4- (4- (5-chlorobenzofuran-2-ylmethyl) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1- b] oxazole Melting point: 210.6-211.6 ° C. Example 14 (R) -2-Methyl-6-nitro-2- (2- (4- (4-trifluoromethoxybenzyl) piperidin-1-yl) benzothiazol-6-yloxymethyl) -2,3-dihydroimidazo [2, 1- b] oxazole Melting point: 203.9-205.2 ° C. Example 15 2-Methyl-6-nitro-2- (4- (4- (4-trifluoromethoxybenzyl) -piperidine-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole Melting point: 180.9-182.7 ° C. Example 16 2- (4- (4- (3,4-Dichlorobenzyl) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo- [2, 1-b] oxazole fusion: 191.4-192.1 ° C.

Example 17 2- (4- (4- (N- (4-chlorophenyl) -N-methylamino) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo- [2, 1 -b] oxazole Melting point: 137.6-141.5 ° C. Example 18 (R) -2- (4- (4- (N- (4-chlorophenyl) -N-methylamino) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [ 2, 1-b] oxazole, 4-toluenesulfonate. Melting point: 212.6-21 .1 ° C. Example 19 (R) -2- (4- (4- (N- (4-chlorophenyl) -N-methylamino) -piperidine-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole, methanesulfonate. Melting point: 171.2-172.8 ° C. Example 20 (R) -2- (4- (4- (N- (4-chlorophenyl) -N-methylamino) -piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole, hydrochloride. Melting point: 170.0-173.7 ° C. Example 21 2-Methyl-6-nitro-2- (4- (4- (4-trifluoromethoxybenzyloxy-methyl) piperidin-1-yl) phenoxymethyl) -2, 3-dihydroimidazo [2, 1-b] oxazole Melting point : 153 1-153. 7 ° C.

EXAMPLE 22 1- (4- (2-Methyl-6-nitro-2, 3-dihydroimidazo [2, 1-b] oxazol-2-ylmethoxy) phenyl) piperidin-4-ylmethyl ester of (R) - (4 -chlorophenyl) carbamic Melting point: 211.6-212.3 ° C (decomposed). Example 23 2-Methyl-6-nitro-2- (4 - (4 - (4-trifluoromethylbenzyloxymethyl) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole Melting point: 138.7 -13.5 ° C. [Table 22] Example Rl t £ l [Table 23] Example 1 Rl R2 p.f. ' aO 2§ -H -B 210.9 - • 213.S 33 -. 33 -Oi -CI 193.9 - • 202.0 [Table 24] Example: R2 F E3 P-f-'C) 34 -Ig ^ ~ - -CH, -Ci 1737-75.1" -. 35 -CH3 -H "CF3 178.4- 181.1 düc 3ß -CHS -CH3"GF3 135.0-137.5 37"CH ^ ~ H ~ 0CF3 195.4- 197.8 dec 38 ™ GH3 -GHj -OCF 158.1 -158.8 3S ~ c? S -H "Cl 187.0-189.5 40 -. 40 -CH, - CHgOHg -Cl 121.4-125.0 41 -. 41 -cu ~ CH-íCH | j -CFa 105.0- 108.5 42 -. 42 -OH, 4-OF hGHg- -H 1925- 195.3 43 ~ G í $ -GH ^ CHjOH -CF * 147.3 - 14S.5 44 -. 44 -CH3 -CHüCHjOCI-fs -CF, 89.5 - 93.4 45 -CHa -CaH? -CF, 103.4 - 107.9 46 -. 46 -OH4 -G4H3"Cl 122.1-124.0 47 -0Ha CHaOCHaOO- ~ CF3 124.7 - 127.0 48 -. 48 -OHj -CH¿- < * ¡Io -CaHs-GFi 157.8-160.4 49 -. 49 -CH3 -C4HS -GFa 117.8-120.2 fifty - . 50 -CHa "CaHe -0CF5 122.5-122.8 51 A -CHS -OGFj 154.0 - 157.3 dec 52 -. 52 -H -CjHs -CF3 172.0-174.2 53 -. 53 -H -OH, -CF3 180.4-190.8 54 -. 54 -H -H -CFa 170.2-180.7 5S -H -CHa -Cl 203.6 -2Q4 dec [Table 25] Example K R3 p.f. fe) or'H NMR 56 -H ~ H -H 215.S- 217.2 57 -H -K -Cl 211.7 -21 Al S8 -K -01 -Ot 1S9.S- 204.0 sa ~ H -M -CF, 213 , 5-8165 50 -H -H -OCF, 21? .6- 218.4 SI -CH3 ~ H -Cl 195.4-139.1 62"" CH3 -H -OGFj 204.8 -UO? .Í? 63 -OH, -H -H 206.I -20S.S 5; H? -Oi -Cl 132.1 - 1 * 5.7 is HH -CF, 199..Í -202.0 m "COCH3 -H -Cl lSft.S-117. <S S7 -CFiOPhCHs- -H -OCF, 115.4-1174? RMN (DMSO) d W2-t, S7 (aH, rn), ltt {3H, fara) t S 5S-g, ??? H, mJ 3.52 (21-1, d, J = lZ. 4Mz), 4? 50H, 4 68 -COCH, "Cl -01 Js] ijaMz) .4.t7 {2H. £ .5, 4.35Í.1H. ÍÍ, J * 109He), 4Jjt { 2H . tes), ß, ßa- «91 { 4H,»), 7.1 i -7.28 (1 H. m, 7.35-7.61 (3H, m), aoKIH, s.) 69 -GOÍGtHc -H - GF- 137.0-1400 70 ~ GO? C? H, -H -CF5 TS9.9- 162.a TI -C¡Ha -H -CFí Í32.S- 138.7 [Table 26] Example m R2 R3 Pf- = C) 72 -CHb -HOHOH) aC? CO- 250.7-254.0 73 -CH3 -H 4-CIPhCHUOCO- 232.0-257.5 74 -CH, -OjH, (CH ^ COCO- 165.0 -167.2 75"a;! -M -CF, PK0H ^ - U3f .2 - 163.5 76 ~ CHa -H 4-CF, Ph < CHl), - 194.9-196.7 77 ~ Críj -H 4 ~ CFJPhCH = CHCHJ- 212.3-214.7 t.sub.f -CHa -CH, 4-CFaPhiCHi.). 2- 144.0 79 -CH, -CH, 4-CF, Ph.GW, 3-172.2 -173-80 -CHS -CU, 4-CF5rf » hOH = CHCH-212.4-214.5 eo 81"" CH3-CH, 4-CFaCFhGHí.CH, QGC ~ 2Q5, S-208.0 ag? o? s -H 4-ClPhCHiOCO- 232.0-237.5 ec S5 - CH, -CH3 4-GlPflCHtGOQ ~ 201.O - 203.7 34 -OH, -OH, 4-0F5 «? CHOOCG- 201.0 - 203.5 [Table 27] O- N w [Table 28] [Table 29] Example R1 R2 R3 P-f- fC) O? NMR 121 -H 4-CIPh- ~ OsHs 217.6- 21 S.4 dec 122 -OH, 4-CIPh- ~ 0, H, 22 = 9.3-223.0 dec 12S -H 4-CF3OPh- -C2HS 221.8- & dec 124 -OHa 4-CF, OPJ1- -C? Z45.1 - 247.3 dec 1H NMR (CDCIJ) d 1.2i3HI.J = 7.01Hz), 191 ~ t, S8 (4H, ni), 2.β2-2.8 (2R m) .3.37C2H, q. Js7.01 Hz, 3 4-3.89 (3H, m), 4.30-4.51. { 4H, m), 125 -H 4-GF3Pb ~ "CZHS 5.5B-5.69C1H, m), 6.74 ~ S.79 (2H. \ 0 0-d 5 (2H, m), 6, ®a-7. Q4C2H,> 7.42-7 ^ 2 (6H. Rn) .I2? -CHS 4-CFjPh- -Cj.Hs 2S1.β - 253.S rie-ß [Table 30] Example Rt p.f. CC) or? RMN 127 -H 237.7 - 239.6 CH, «F 229.G - 230.5 d 128 "H NMR ÍOMSÜ) £ 1.7TC3K s> 421i1H d, J = 11.03Hz), 4.34Í2H, s), - ° - - 0- F 4.40 (1 H. d, J = 11.03Hz), 6. SSÍ2B, dJ = 8.44Hz), 7.1O-7.20C8H.ro), 7.42 (2H, .J = S.44HzJr 7.57-7.72C8H, 130 m). S.22C1H, sX ~ ° ™ ™ 0-f-F 218.0 - 221.0 dec 131 [Table 31] [Table 32] 141 -. 141-CHS-CHs 4-CIPhCHlt0CQ-132,4-t35, Q 1 2 -CHj -OHs 4-CF, PhCHi? CO-143 -cn3 -e 4-CF, PJ? CH-CHCH? - 1ß0.f- t637 -CHj -CfH5 4-QFjOPÍ 125.2-128.1 145 -OH? - CHj 4-CFjOPh- 197 -13 &.2 4-C "Pfrr 190.S-183 47 -CH., Jl -CFaOf = h- 45,6-14 &3 3 -QH5 -K 4-CfPi? - 163.3-167.3 4i -CHj. -H 4-CF1OPhOÍ-QHí > í ~ f «XSM431 00 - OHj - OHj (OH¿0000 ~ 153.6-154 51 -CH» -H 4-CFaOPhCHj- 181.7 - 183.0 32 -CPhCHi- 1S3,7-T8ß.B-Cplj-H 4-GF, PhCHr 173.0-175.3-GH |] -H 4-Q? Pi? QH? OOO- 125.2 - 127.6 35- CH] - H 4-CF3OPhCHjOCO "120.5 - 124 56 -CHa -1-1 4-CFsPhCHOC - 103.5 - 107.3 'T NMR (GOGIj) í 1.4S-1.S2 (2li m),? .76Í3R e), 2 .DB-2.21Í2H. ra), 2 0-3.0S &H, m) .3.35-3.47C1H, m). 3 OR-3.S3J1R, m} "3 8-40SÍ2H, m > , 4.16ÍÍH, d. 157 -CH, -H 4-CFrph- ü = O.20Hsú, 4.50 (1H, d, J * 2QH-d, < 3.53- &G5 £ 2H.m), S 9- &77Í2H , i 6.ga-6 3í2Ht mi 7.43-7.51Í2R r «X 7 5Í1H, s) 'H NMR (CDCSJ) d 1.20-1.37 (21-1, m> 1.46 (SH, s), 1.7 (X3H , BJ.1.94-2.07 (211 fcrm), 2.77-3.01 (214. brm). 15B -CH, -H tCH ^ OOCO- 3-23-3.41 (2Hr fame), 3.94-4.1 4H. m} "4.Í4C1H, á, j! = 10.t9Hí? 4.49 (1 H.4 J-tQ.15H? 3, 6.50-ß.5a (2H, my ßJ67-676 (2Hli (, 755í1HI «) 159 -OHj ~ GH5 4-OFj.OPhGG-1S9. 2- 132.0 ISO -OHj -GHj 4-CFjOPhHHGO-179.0-182.5 [Table 33] Example Rl 2 R3 p-í ro 161 ~ ÜH3 -GHa 0-Hf V-Ct 158.9-460.4 182 -. 182 -CHa -GHa 143.0-146.5 163 -. 163 -GH3 -CH3 163.9-166.3 164 ~ CHa -H / Ar l "J 161.7-165.4 165 -. 165 -CH3 -H (L kv 185.7-188.8 [Table 34] Example Rl m R3 p.f. C) O! H NMR 'H RMH. { GBCy é¡ 1.B2-1.73C2H. m), 1 3-1.67Í5H, m),? J96-2.12Í2H. m > . 2.77Í.3H. s), 2.S6-3.03 2H,), 168 -OH, 4-CP5Q «1- -CH, &38-3.6 £ 3H, m > . 4.-Q0-4.13Í2H, m% 4.23C1H, d, J = l0¡.1H¿? 4.50 (1 H, d J = 10.2 HzX 6.67-6.?4 (2H.m), 6.7fr »d.g4 (2K, m, 7.Q2-7.10ÍZH,« tí.7.18-7.25Í2H, ml 7.56 (1 H, s) $ 7-CN, 4-CF, OÍ * CH, ÜCO- -GH 3 130.9-1 & 2: 168 -CH, 4-CFSÜP »? GHí- '-CH 143.1-145.7 169 - CHa 4-GF5OPhOO- -CHj 178.8-183.7> H NMR (COCÍ,) d U4-1Ü ?. {SH.m 2.SO-2.es (2H. W?), 2.68-2.83 (2 », m), 2.97 <3H, s, 3.42-3.56 (2H, mX 3.87-4.17 <4H.m \ 29 (1 H, t *, J = 10.3H? X 4.50 (1 H, * 170 -CH3 4-CF &OPI.NHCO- -CH, d = 10.2Hz? 4.55-4.66 (1 H, ml 8.46-TJS {tH, hrX &84-6.93C2H, mX 7.1Q-7.18l2H, m), 7.37-7.44 (2H, m), 7.4a-7.57 (2H.m..7.S8 (1Hr s) [Table 35] Example MS (MH.). Í7ß -0 442 179 YYktA * fj 492 [Table 36] Example Rl EM (+1) 180 \ // ff 476 84 J 451 [Table 37] Example Rl EM ÍM + 1) m ^ ¿? 499 You have "0.1? M 470 m H 450 [Table 38] Example Rl EM ÍM + t) (SS 450 F 200 -AF 201 4m [Table 39] Example R1 R2 R3 R4 RS Rβ R7 -EJ-1? íl 202 -. 202 -CKj -H -H -H -Cl -H -H 484 203 -. 203 -CH.3 -CHj -H -H -Cl -H -H 49S 20 -Hj -H -H -HCl -Cl -H 618 205 -CH3 -H -H -HQ0? S -H kl 534 206 c? 3 • H -H -CFg -HCF3 -K see 207 CB3 -H •• H -H -CiH »506 208 -CH3 -H -H -H -H -H 450 209 -CH3 -H -M -H -OCH, -H 480 210 -H -H -H -CI 484 211 -CB3 -H -H ^ H -H CE -H 484 2 2 -Hg? - H -CHj ^ H -K 464 213 -CH 3 -H -H -OCHj -OCH 3 -OCH 5 -H 540 214 - 3 -H-H -H -OCR. -H 534 215 -CH3 -K -H -H -F -H ~ H 468 216 -H -H -H 493 217 -CH »-H -H -H -OCJHÍ -H -H 494 2? S • CHj -H -H ^ H -CgHs -H -H 478 in -CH3 -H -H -H -H -CO2G2H5 -H 522 not -CH3 -H -H -H -H -OCF3 534 221- CH3 -H -H -H -H -OCH F- 516 223 »CHj -H -H -H -OCeHj -H -H 542 224 OH3 -H -H -H -H -Of -CJ 51 $ • ¿JJ- -CH3 -H -H -Cl- Cl -Cl 51a 226 «CHa -H -Cl- -CI -H 518 227 -H -H -cr -Cl -Cl 552 228 -CH3 -H-CH, -H-CH 3 -H -CH 3 225 -CH 3 -H -H -OCH a -Cl -H 514 230 -CH 3 -H -H -H • CFa -H a 552 231 'CH 4" H »F • F -F -F -F 540 232 -" GH $ -H -H • H ~ UQ - -H 495 233 • CHg: -H -H -H -CH -H -H 475 23 -CH3- H -H -H -SCH3 -H -H 496 235 -CH3 -CK3? «H -Oi? Cl -H 532 236 -CHj -CHj -H -H -0CF3 -H -H 543 237 -GHa -CH3 -H -H 'C? * H -H 520 238 -CH3"CH -j -H • H -H -H-464 [Table 40] Example m R2 .JüL, R4 R5 m R7 EM (M-H) 23S -CH3 -CH3 * H * H -HCl 498 240 -GH $ -CH3 -H -H -Cl -H 4913 241 «CH? «CH3 -H -H-CHs -H -H 47fi 242 -CBg -CH3 -H -OCH3 -OCH3 -OCH3 -H 554 243 -GH3" CHS -H -H -OCF3 -H 54S 244 -CHj -CHj -H -H -F -H -H mz 2 5 -CHs -CHa -H -H -N (CH¿) s -H »H i 246 -CHa 'CHa -H» H -OC2Hs -K -H 508 247 -CHa ~? -H -H -CjHs -H -H 492: 248"CHg -CH3 -H -H ^ HCOCHa -H -H 521 243 -CHa -CHj -H -H -H 536 2S0» CHa * CHa -H -H -H -0CF3 548 251 -CHa -CHj -H -H -H -OGHFa §30 252 -CH3 -VHJ -H -H -Cl -H • OCF3 S82 253 -ÜH3 -CHa -H -H .QG_H5 Í -H SSS 2S4 -CH3 -CH3 -H -H -H -Cl -Ci 538 255 • CH3 -CHa -H -H -Cl -H -Cf 533 25ÉÍ "CHg -CHa -H -Cl -H -Cl «H 532 257 -CH3" CHj -H * H -Cl -Cl- to 586 2SS -CH3 -CH -H -H «QCHj -Cl -H 52ÉS 253" CH3"CH3 -H -H -SGH_ -H -H 510 [Table 41] Example R1 R3 EM &M) "I read" 4-C! PhCHa- ~~ * "~" 493 261 -CH3 -CHgGgHs -H 464 - Ha a-ciPi ?? H £ - -H 495 2S3 -CH3 3-CÍPhCHj- -H 493 264 -CH3 4-CH3PhÚH2- * CH3 492 285 -CH3 3,4,5-fGHiObPhCHj- -CH, 568 26S -Ctf3 -CHIC ^ MS -CH2CHZN. { CH3- '535 267 «CH3 4-CHaOF, hCH? -H -4498 -CH3 4-CIP (? GH8- -CHs 512 aes -CH. 4-FPhCHr -H 482 270 • CH3 3, (CH3.0) 2p CHs. -H 524 271 -CH3 -GHjcCHpQCHa -CH? CHgOCH3 490 272 -CH3 (QaHsJsNíCHds- -C_Hg 501 273 -CHS-cIclo-CjH) -H-4S4 274 -CH3 4-GEPf? (CH2Jr -H 512 276 -CH3 -CHr cycle .CßHt1 -H 470 [Table 42] Example Rl R2 R3 EM ÍM-t-I) 278 -CH. "X I X \\>) -CH3 522 278 -. 278 -CH3 - -H 454 [Table 43] Example R1 R2 R3 EM (M + l) [Table 44] Example R1 R2 R3 EM (M * 1) [Table 45] Example Rl R2 EM (fvf-í-Í) [Table 46] Example Rf R2 EM (M + D [Table 47] Example R1 p.fifC) [Table 48] Example Rl RZ P ffo a 'H R H _ ~ Í03 -CHj:? JF | 0Ph-' -QÜCH, I4ftí? = - 14B-1 30 -CHJ. 4-CF, 0Ph- 1I0Ü-119J, 305-CÍIJ. -CF? QFh- -Ci -f- -306 -cu * 4-CiP /] - -OH * 1418-1461 am -GH-, 15 4-1S5.Ü 'HRMN í CDCf j) di Hr 1 Í-EHL , fartp > , 1.67-1 6H, fcrp ?, 2.13C1.5H, ß), 3.201.5H. ñ 2.46-2.7J2Í2H, teitl 3.12-3.23 (1 H, ÍJÍW >, W3 -Ctf ^ 4-CFjQPhGLij- -cogfH? 3,27 ~ 3.3B¡! ÍH, fcprA 3.S4-3.63Í2H, hm # g .SM.TfóH,). H, .2dC "H. S? -5, íf, 43 (lH, * J = 1015Hz>.".} S (1H, s ?, 463Í1H, e), BI ??? 6534X. Bprpt. 7.12-7j3Q {4ft «&7 B (W, ß) 353 -? 4-CFjOPh- • H iBt. * - 182.5 310 -CH. 4-CfPl? - -H 177 * - J7B, f 311 ' € at, 4-CF, PI * Í- -H 164.7 -fß5? 312 -CB $ 4 ~ GF, 0PhCH, - -ty - 163: 4-165.2 313 -CHj 4-CF3OPhOHa- "vFfj 180.5 -ISP B 31 £ -Clf, 4-qiPifcchj- 169 - 170.6 315 -CH., -i-CFjPl-CTJl- * CH; 166.7 -1 «7.G 316" CHj í-CF, 0P CHr -H JE3S- € l 7.E 317 -cüj -H 163.8 -1fl @, 3 31 S -CH? -5-OFIPISCMÍ- -H IST.ß-l'fiQ.B? RMN ícpcy i,:? & < * i , IH, brm), 1.60-1, mm, \ 2.46-2 6C2H, birft 3.0CK -, * Mf2H, brml 3 -3. H G? Í3S, 3.97-4. & 3Í2IÍ p? Í, 4.17ÍIH. 319 -. 319 -CH »-i-CFjCFhGH, - (cii ^ coca- < f" J = l «.12Hr.}., 43S-4S5 { * Ir m), £ .70-8.Sl% 2H, J?), Β, 8i-β, S5ZH. IR) ii xsatzH, m > , T ^ O-Í.SiíSH, «& 7.50 (1 H, s)? NMR (O??? 11.25-1.54"11H.bmr 1, S £ M.B4áH, rp), 2A3-lBB & bír bpp), 3.00-3. £ 2 (2H, braa 3.51 (2H, 4 3, 3B «4 £ I6 £ 2H. 320 -OH, 4-DIPCHIT rCJUcCOGO- niM.17r.1H.d, JslOLlCHz? 34-4.46Í2H bm? 4,49.1 H, i Jfcia.l * Mz), & 7fi2H2, d.D = 8. &1HX8H8, 93HH.brm) .79-7.21 (7q. Bpp.),? .2BlH, iU ^ .2flIk .55l1H, 8) ? MN (CDCip 1.31-1.B7Í 11 HL mi K 1.6I-1.SISÍSH.M. HS-Í72Í2H.bínl 3? S-3.aaí2H bren), 3.52Í2H, 4 J "JítGaHz) .3.Í5 -Ü-4.QSÍ2H, ra ?, Mi - & 4-SF, Pl) Q, H, - (QMJÍGQQO-4I7? 1H, A g £ M »» > I 44I- .5t (3H, ml S YES = K d, J = 8 HzJ. € .SS- S.SeiM f * tn) .7,? &-7,43í2H, brm.}, 7.S51H.y, 3L5ÍK2H. < t4 = 7. »5Hd [Table 49] Plí J axis Rí R2 m R4 is Rd EM. { M + l) 322"- -Mg -H-H -H-CHa 490 323 • CH, ^ H • H -CHa -H 490 324 -CHg ^ H 1« H • H .OCF3 sso 325 - CHg -p -H -H -DCFa -H sso 32β • CH3> H -H -F -t -CHs 508 er • CH3 -H • H • Cl -CFa -H 57 $ gg &-CHa -H -H * GH8 -H -H 4§0 323 -CHg -H -H -C (CH3.}. -H -H 332 331 -CH3 -Cl -H -H -H Cf S44 332 -GH3 -H -C ) -H -c? -H 344 333 -CHa -H -H -SC »* -H -H 52S 33» CM3 -H -H -COCBHS -H -H S80 SSS -GH5 -H • H -F -CFa * H 5S2 age -CHa -H -H -H • <5Fi -F 5ßñ 337 -CH3 -H -H -C? -H- to 544 ass -CHa -H -Cl -H -H • to S44 ass - CHg-H -Cl -H -Ct-l STB 34Q • CHa -C? -H -Cl -Cf -H 578 341 »CHj -Ct • H.« • H -Gl 57B 942 -CHa -H -H- OCHa -H -H sm 343 '? G -H -H -H -H -N0_- 521 344 -CHo -H -K "Cl -Gl • H 544 345 -CHJ -H -H -Cl -H -H 510 34B ^ OH ^ * H -H-H-H 510 347 -CH3 »H -HCN -H -H 501 84 $ -CK3 -H -H -H -CH -H 50Í 349« CH3 -H • H -H -Cl -Cl 544 350 -Ha HH -H -OCCCHa -OCpj -H 564 3S? "Cr" rl -H -H02 -H -H sat 352 -CH3 -H -H -NfCHsfe -H -H 519 ßS3 -CH $ M • p -H "" H -OH 4S2 [Table 50] Example 81 RE m R4 m R6 EM. { +1) 354 -. 354 -CHS -H OGH5, -OH -H 552 sm "CH ^ * H -OH-OCHa -H sgg 356 -OH3 -H -H • CgHjj • * H -H 504 357 -CHa -H -H- G & H13 -H • H? 35B -CH3 -H -H-OCHaCsHs -H -H 582 359 -CH »-H -H -OCsHs -H -H 568 381 -CHg -H * H« OC6Hlg -H • H a? a 362 -GH3 -H -H «OCFg -H • H S80 [Table 51] Example R | ft $ EM (MH) 365 ^ IV! ^ C O * "367 -CHS?% ^ 4S0 378 -. 378 -CHA. ^ S3ÍI [Table 52] Example JQ R2 EM (M + l) 374 -. 374 -CH, ^ OJ- ^ 547 376 -. 376 -CH3 52.7 [Table 53] 379 -. 379 -H -O-CH, 165.4-168.5 [Table 54] Example R3 R RB 7"-Oh -H -H -Cl" -C1"-H 122-124 3 @ 3 -CHj -CHj -H 'Cl -H -Cl -H 16B.5-167 SS4 -CH3 -H -H -H -CaH? -H -H 3B5 -CH3 OH3 -H -H -Cjl-fy -H -M 19B-1T9 -CHj -H -H -H -F -H -H? U a- isa, ? 3S7 -CH, -CH, • H • H -F -H -H 175.7-177.4 358 -GH3 -H -H-4-GF3DPÉ1O- -thi -H 167.4- 17D.2 -CH3 -CHa- H -H 4-CFsOPf5? -H-H 167.4-170. »390 -CHj -K -H -a -Cf -rt * H [Table 55] Example Rl R2 R3 E4 R5 R6 R7 P-f. (° C) 391 -. 391 -CH3 -CH2CH2OH -H -H -CF3 -H -H 114.5-117.3 392 -. 392 -CH3 -CH3 -F -H -CF3 -H -H 197.5-199.2 393 -. 393 -CH3 -CH3 -CF3 -H -H -H -H 189.6-190.2 394 -. 394 -CH3 -CH3 -Cl -Cl -HH -H 176.9-178.2 395 -. 395 -CH3 -CH3 -Cl -H -ClH -H 181.6-182.4 396 -. 396 -CH3 -CH3 -H -CF3 -H -CF3 -H 193.8-195.3 397 -. 397 -H-CH3 -H -H -CF3 -H -H 167.7-169.0 [Table 56] Example, R1 g m BS R7 EM (ívM) 399 -. 399 -CH 3 -CH 2 H2CH -H -H -H * H 517 399 -CH 3 - ^ ii. -Cl -H -H -HCl ßSß 400 'GHa "CjHg -H -H -CHpHfe -H -H 534 401 -. 401-CHg -CZH ^ -H -H ~ C§H; -H -t 568 402 -. 402 -GH $ -OH »-H -H -Q? HS -H -H SDd 403 -CHa -CHj -H -H -QC Ks -H -H 570 404 * CH3 -CHa -H -H -OC? 2 EHS -H -M 534 405"GHa • CH, • H -H -OC.H17 -H -K 606 408 -CH ^ -CHj -H -H -Níci-y? -H -H S21 407 -. 407 -CH3 -CH3 -H -H -C Hs -H -H S34 4¡JB -CH3 -CHa. -B -H -CHJ¡CH (CHs to -H -H 534 409 -CHa -CHa -H -H -N CfiHgJa -H -H S4S 410 «CH3 'CHj -H -H -OCH (CHa) to -H -H 5363 41.sup.-CH.sub.CH -CH, -H -H -OC (CH.sub.H -H.sub.44.sub.44.sub.44 -CH.sub.3 ~CH.sub.H -H -OtOH.sub.HCH.sub.H -H.sub.19.sub.49 -13.sub.3 -CH.sub.3 -CH.sub.3 -H- NiC.sub.4 H.sub.9. s -H -H ees [Table 57] Example Rl R2 R3 p.f. (° C) 414 -. 414-CH3 (CH3) 3COCO- -CH3 415 -H (CH3) 3COCO- -CH3 416 -CH3 4-CJPh- 4-CIPh- 40.3 -40.7 417 -. 417 -CH3 4-CF3Ph- 4-CF3Ph- 104.0 - 108.0 418 -. 418 -CH3 4-CIPh- 4-CF3Ph- 419 -CH3 4-CF3PhCH2- -CH3 420 -H 4-CF3PhCH2- -CH3 167.7 - 169.0 422 -. 422 -CH3 HO -CH3 207.4-210.0 427 -. 427 -H-CHa 219.6-221.1 [Table 58] -CH3 432 -CH3 A aCFs 194.2-196.0 -CH3 433 -H - CrCFs 174.0-175.3 [Table 59] Example Rl R2? 3 ___ JEM ÍM + J) 434 -CH3 / ~? _ "CHS 547 435 -. 435 -CH * / ^ r _ -CH3 561 [Table 60] Example Rl R2 B3 E4 R5 B6 p.f. (° C) 439 -H -H -OCF3 -H -H 160.5 - 164.0 440 -. 440 -CH3 -H -OCF3 -H -H -H 187.4-189.8 441 -. 441 -H -H -OCF3 -H -H -H 153.7-156.3 442 -. 442 -CH3 -OCF3 -H -H -H -H 205.8-208.5 443 -. 443 -H -H -H -H -HOCF3 155.9-159.0 [Table 61] kkA 0? > A M1-R.3 or R2 Example Rl K2 3 p-f tcfe _ 444 -. 444 -CHa 4-CFaÜPh- -COCH3 148.6-149.1 445 -. 445 -CHa 4-CF30Ph- -CaH5 116.8 -11 &2 446 -. 446 -CHa 4'CF3OP - »CH? 135.6- 140-9 447 -. 447 -CH3 4-ClPÍ «CHs 141.6-145.1 448 * CH $ - «FaFhs- -CHa 151.4-156.0 449 -. 449 -CHa 4-CftOPhCHr * CCCH3 450 -CH »4-DF? OPII-» H 181.9-1B2.5 451 -. 451 -CHs 4-ClPH- -H m.é ~? M.i 452 -. 452 -CHa 4-CFsP5- -H 164.7-165.8 453 -. 453 -. 453 -CH5 4 «Gi GPtiGH" Q? 163.9-165.2 454 • CH 4-CFaOP? .CHr -CHa 180.5 '1 BOJ 455"• CHs 4- PhCHa- -CHa 169.5 - 170. © 453 -CHa 4-Cp3P CH ^ -CHj 166.7-167.5 457 -. 457 -CH3 4-CFa0Pí? CH -H 163.9-167.6 4S & -CHj 4-CIPhGHr -H 163.B-I6 & 459 -. 459 -CHJ 4-CF3PhCH2- -H 157? -160? 4m-CHa 4-CFa0PhCH2- (CK &COCO-481-CHs 4-CIPhCH. (CHdiCOCO-462-Gti% 4-CF3PhCH {CH5.}. 3C CC-463 -CHa -CF3OPhCHsOCC -OH 4S4 GH3 4 -CF3OP CO- -CH3 48S «CHa 4-CFaQFf? NHCO- -CH3 [Table 62] Example Rt R2 R3 p. 46β-CHa-CHS tGH¡fcCOCO. 159.8-161.0 46? -CHa-CHa 4-CFaOPhCQ- "4.3-155.6 463 -CHa -CHb 4.CF5OPhNHCO- 143.7-149.3489 -CHa -CBs 4-CF5OPf CH2CCO- f 39.7-1 0.B 4-70 > CHf -CH5 4-CF30PílCH3- 134.7-157.0 [Table 63] Example R3 R4 Rd EM ÍM + t > 472"CHj -H -H -CHÍCH 2 -H * H 521 473 -. 473 -Ha -H -CFa "H -H -H 547 474 -. 474 - £ i »p3 ~ H -H -CJCHsJa -H -H 533 475 -. 475 -CHJ -H -H -CN -H 504 476 -. 476 -CHi -tí -H * CßHs -H -H 555 477 -. 477 - Hs -OCFa -H -H -H -H 583 47B »CHj» H • CHa -KH -H 493 470 -. 470 -CH3 -H -H -OCFa -H -H 563 480 -. 480 -Ha -H -Gl -H -H -H13 4S1 -CH3 -H -H -F -H -K 437 as «CHj« H -OCH3 -H -H-539 4 «3 'CHg -H -Cl-CI -H -H 547 484 -. 484 -CHs "CFg -M H -H -H 547 485 -. 485 -CHj -H • OOeHft -H -H -H 571 4Bβ "CHa» H -H -SCH¿ -H -H 525 487 -CHs -H -CCF9 -H H 563 41"-CH 3 -Ci -H -F -H -H 531 4B3 • CHa "H- 1 -H -Cl -H 547 490 -CHj -Gl -Cl -thi -HM 547 431 -CHa -H" CH, "H -CH3; -H 507 492 -CHa -ClH- H - -H 547 4S3- -CH $ -H -Hc -Hj -H • H 507 494 -CH3 -H -H -Cl -H -H 513 ß5 -CHa -H -H • CF, • H -H 547 4S # • CHj -H -H -CHa -H -H 493 4? 7 -CHs -H -H -H -H 470 [Table 64] [Table 65] Example Rí RZ ña 4 m EM IM + t) 499 -. 499 -CK3 -H -H -OCHa -H -H 4S5 5Q0 -CHa -H -H -OOHa -OCH, -H 525 501 -. 501 -CHa -H -H -H -H 465 sea -Qr -H -H -H -H -Cl 49? 509 -. 509 -CHj -H -H -H-! -H 499 504 -. 504 -CH, - * H -H -O -H -H 93 505 -. 505 -CH3 - »-a -CE -H -H 533 506 OHa -H -H -CH, -H -H 479 587 -. 587 -CHa -CH to -H • CH »-H -H 493 508 -. 508 -Ha -H -H • F -H -H 483 SOS? -CHa -H -H «CQAHc -H -H 537 510 -. 510 -CHa -H -H * CN -H 490 511 ~ CH3 -H -H «- CF» 533 512 -CH3 -H • H * H -CFS -H 533 513 -GHg -H • H -CFa - H -H 533 514 -CH3 -H • H -OCFa -H -H 549 515 -CH8 -H - -HH-OCH. { CHJa 523 51 © -CHS • H -H -CHa -H -CQtCj.H5 551 517 • CHj -H -H -OCH3 -H -COíCHs 553 61ß • CH, -H -H -Br -H -F 561 Sl? -OH -H -CHa «H -H -F 497 520 -CHa -H -H 'C3H? -H -H 507 5S1 -CH3 -H -H -Cl -F -H 517 522 -CH3 44 -H -NCfe? .F 528 523 -CH3 -M > H -CH2C H = CHa • H -OCH3 535 5S4 -CH3H • H -H • N. { C? HS5 * -H 536 525 -CH, -H-CH CHCHstds) -H -H -OCÍH6 543 526 • CHj -H -H-CHÍCHs). -H -H 507 527 -CHa -H -tí > CH? CH COCHs -H -H 53S 528 -CH3 -H • H -H -MHC ^ Hs -H 556 523 -CH3 -H -H -CHaCCfeCH, -H • H 537 530 -CH3 -H -H -OCH3 - H -Ct 529 [Table 66] Example m R2 R4 R5 m EM (MH) sm - Ha -H -H -COjCHa -H S23 532 -CHa -H -H -COC = HS -H -H 521 S33 • CHj • H «H -COCHa • H -CHT 521 534 -. 534 -CHa -H -H -NHCOCHa -H -H 523 53S -CHs -H -CHa -CH3 -CH3 • H SD7 SSß • CHs -H -H • H -H -CHaC ^ Hs S55 537 -Ha -H- OCH3 -rt -H -C02CHa 553 535 * CHs • H -H »-H, -H * H 5 * 1 539 -CHa -H -H -H -2-BENZTI ^ ZOLILO 59S 540" CHs • H -H -1 PIRRIL0 -H -H 530 541 -CHs -H -H -CgHs -H -H 541 542 -CHa -H -H -OCRaC • H -H 571 S4S ^ CH ^ -H -H -CHgCgHs -H -H 555 544 -CHa -H -H -cycle "^ 5 ^ H -H -H47 545- • CHs • H" H "(xy -f;? • H -H s S46 -GHa -H -H- cycfo-CsHa. -H -H 533 547 -CHa • H -H -H • QC &Ha. -H 557 54 © «CHa + ¡« H -H -H 549 [Table 67] Example Rl R2 R3 R4 fid R6 ^ 1 ^ 549 -H "H -M" Cl -H -t 198.13 -20-2.5 550 -H -H -HCFs -H -H 197.0 -200.9 [Table 68] Example ñí Z R3 R4 R5 Rß EM if.íi-1} S5í -CHa -H -H üJ * -H -H 532 55-? -CH3 -H -H -H "? S32 553 -. 553 -CHi -H "H» Ñ -H -H 531 554 -. 554 -CHS -H -H -CHa -H - N JW ^ 596 H-. SSS -CHS -H -H -H -H 582 O GH ^ 55a -CHa -H -H _1 ~ ?? - ACHa -H ° H 649 N Y ^ 0 CH3 [Table 69] Example < R1 R2 R3 4 R5 R6 R7 EM (M + 1) 5S 7 -CH 3 -H -H -H -H -H 505 558 -CHa -H -Cl -H -H -H 542 559 -OH 3 -H -H -H -HCi -ty 542 560 -CH3 • H -H • H • CI -H • H 542 Sßt -CHa -H -OCHa -H -H -H -H SSS 562 -CH3 -H -H -H -H -OCH: i -H 538 563 -CHa -H -H 4 * -Cl -Cl -H 576 S64 -CH, • H -ty • Cl -H -Cl -H 576 565 -CHj -H- H -CF3 -H -H-575 5 ß -CH3 -H-H -CP3 -H-57β SS7 -GHj -H -H > H -OGFj -H -H 592 sßa -CHa -H -CH3 • H -H -H -H 522 563 -CH3 -H -H -CHa -H -H -H 533 570 -CH3 -H -H -H- CH 3 -H -H 522 57t -CHa -H -P * H -H * K -H 526 572 -CHa 1 -H • F • H -H • H 526 573 -CH ^ -H -H -H -F ~ H -H 526 574 -CHa -H -H -Cl -H -Cl 57 @ 575 -CHa -H -tH -HCN -H -H 533 57β -GHj -H -H «CFU -H • CFs -H 644 577 «CHa -H -H? -Cl -CFa -H 610 57S -CH3 -H -H -H -OC ^. { s -H -H 600 57S OH3 -H -H • HGQH * -H -H 552 580 -CHj -H -H -CHH -H -H 554 581 -Ha -H -B -H -COCHj 44 -H aso 582 -CHa ^ H -H -H -CHtCHafc • H -H 550 584 «CH3 • H -H • H -Cl -H-CHa 556 585 -CHa -H -tí • M • OC« H9 • H -H 580 586 -CHa • H -H -H -CßH3 -H -H 584 587 -CHa -H -H -H -C-CHjJj -H ffH 564 56 < 3 -CHa -H -? • you -OC7H? S -H -H 622 SW - Ha -H -H -OCHFj -H • H 574 590 -CH3 • H -H • H • CUjCßHs -H -H 59S -CHa -H -H- H -CdH (7 -H -H 620 [Table 70] Example R1 R2 R3 EM (-? - 1) 592"GHj" CHgOjHs • H 522 5 # 3 * CHj "(CHí) gC§H? S • H me 594 -CHs - cycle-GsHii -H S14 [Table 71] Example Rt Fí2 EM íM * t) 6O0 -CHa A% A ^ or Sa9 ß «2 -CHs JOQ 51 S 9 603 -QHa? * Yes? A \ 521 A ^ A- 604 -. 604 -cH - U 522 eos -cf ^ H "* 63S 60S -CH3 = 0 S3 & or 615 -. 615 -CH. V [Table 72] Example R1 J 8_ EM ft.H-1) 612 -CH3 si-,. 535 $ iS -CH3 L 4Í® 616 -. 616 -CHa x S33 O "O [Table 73] Example Rl R2 EM fluH-1) 323 -CH3 517 SSS -CH; XX > YES5 627 -. 627 -CH3 V .O ^ p 629 -. 629 -CKa - > : N 5S? A3 [Table 74] Example Ri RZ EM W-1) 533 -. 533 -CHa < ? ß- (^ 5ßt 63a -CH, H ^ KF 83d 640 -CH3 jf - ^ _ ^ ™ CI ggs [Table 75] Example R1 R2 EM ÍM + J) 543 -. 543 -CHs Jt 528 H O [Table 76] Example Rl E2 P-f. (° C) 646 -CH3 4-CF3OPhCH2- 204.8-206.7 647 -CH3 4-CF3PhCH2- 198.0-199.2 648 -CH3 4-ClPhCH2- 197.6-198.2 649 -CH3 4-CIPhNHCO- 212.7-213.3 650 -CH3 4-CIPhN (CH3) CO- 189.4-191.6 651 -CH3 4-ClPhN (C2Hs) CO-168.6-171.6 652 -CH3 4-CF3PhNHCO- 216.2 - 217.1 dec 653 -. 653 -CH3 4-CF3OPhNHCO- 218.3 - 218.5 dec 654 -. 654 -H 4-CF3PhNHCO- 179.9-180.7 655 -H 4-CF3OP NHCO- 187.6-189.8 656 -CH3 4-CF3PhN (CH3) CO- 195.8-199.1 657 -CH3 4-CF3OPhN (CH3) CO- 181.0 - 184.2 658 -H 4-CF3PhN (CH3) CO- 148.7-151.8 659 -H 4-CF3OPhN (CH3) CO- 150.1-152.6 [Table 77] Example Rl R2 P.f. (° C) 666 -. 666 -H - - - ° -CF3 248-250 dec 668 -. 668 -H ~ N N- ~ CF3 259-260.5 669 -H - -0-F 248.5-250 670 -CH3 -N N Q-CF3 269-271 dec 671 -. 671 -CH3 -0-Q-F 274-276 dec [Table 78] Example R1 p.f. DC) S75 -H - N J-N-C ~? 8065-268 879- -H CFsOFh. { CH2k- ßm -H CF3OPfs (CH3) [Table 79] Example R1 R2 EM '. { M + D 6M -CH-, _ß 's eaa -OH * -O A S75 eas -CHa. Cl 60-5 Cl 686 ^ CHs 'Table 80] Example m Rl R3 E C) CF SBS -CH_- -H '^ - ^ ^ f * S-2QZ? ? »-H -H"?] F ^ «0.0- 151.9 [Table 81] Example Rl E2 p.f. (° C) 691 -CH3 (CH3) 3COCO- 261.0-266.3 dec 692 -. 692 -CH3 -H 693 -CH3 4-CF3OPhCH2-238.2 ~ 240.3 dec. 694 -. 694 -CH3 4-C! P CH2- 247.8 ~ 248.5 dec. 695 -. 695 -CH3 4-CF3PhCH2- 247.7-248.4 dec 696 -. 696 -CH3 4-CF3PhCH = CHCH2- 221.0-226.0 697 -CH3 4-CF3OPhCO- 248.0-252.0 698 -CH3 3,4-CI2PhCH2- 222.6-225.1 dec. 699 -. 699 -CH3 4-FPhCH2- 247.7-249.5 700 -H (CH3) 3COCO- 250 dec 701 -. 701 -H 4-CF3OPhCH2- 200 dec 702 -. 702 -H 4-CF3P CH2- 200 dec 703 -. 703 -H 4-CIPhCH2- 200 dec [Table 82] Example Rl R2 P-f.CC) 704 -CH3 4-CIPh- 250 dec. 705 -CH3 4-CF3Ph- 266.2-271.2 dec 706 -. 706 -CH3 4-CF3OPh- 286.4-288.2 dec 707 -. 707 -H 4-CIPh- 708 -H 4-CF3Ph- 250 dec [Table 83] Example Rl 2 A ^ 71 ß -CU, (CH? C? CO- 717 -CHa 4-CIPhCHa- 150.3-1 S3.9 719 -Ct 4-CF8OFt? CH2- 1130.6-153.5 720 -CHs 4-CFgPh- 1515.6 -155.1 721 -CHa 4-CFaOPIl- 134.0-137.9 722 -CHa -CIPh- 140.7-151.2 723 -CH3 4-CF ^ OPhCHapCO- 90.2-93.0 724 -CH3 -CF? PilGHa0G0- 86.7-89.0 725 -CH3 CEPhCH ^ OCO- 109.0-113.3 72 »-CHa -CIP MHCO- 72β -CH5 4-CF3PiNHC0> 208.5-212.0? M .CH, CF3Ph (CHd. 149-5 - 154.0 m" CH * * ********* Cdiolorohydrate) 732 -CHj 4-ClPf? CO- 733 -CHa 4-CFsPhCO- 734 -CHS 4-CF, 0PhC0- [Table 84] Example Rl R2 P-f- O 736 -. 736 -CH,? NM, ^ 0J CF, 199.6-200.1 .CF, 737 -CH, / ° -0 133.8-136.2 738 -. 738 -CH, ^ crxx? -CF3 184.9-185.9 739 -. 739 -CH, XTTX -CF, 193.9-195.9 740 -. 740 -CH,? Xt? CF, 215.5-217.4 742 -. 742 -H ^ -N ^ ^^ ci 215.0-215.9 [Table 85] Example Rt R2 p.f.

[Table 86] 756 -. 756 -CH, -CH3 ^ -0- ° ^ 172.5-175.2 [Table 87] 761 -. 761 -CH3 -H -H ~~ ~ c * -H -H 248.8-251.5 762 -CH3 - -HH --HH -H -H 218.4-221.0 763 -. 763 -CH3 -H -H -H -H 145.6-147.8 764 -. 764 -CH3 -H -H ^ H, -H -H 241.2-242.5 765 -. 765 -CH 3 -H -H -O -H -H 766 -CH 3 -H -H -cac '-H -H 767 -CH 3 -H -H -ce "3 -H -H [Table 88] [Table 89] Example Rl R2 p.f.m 778 -. 778 -CH; 175.7-178.0 & [Table 90] Example Rl R2 R3 P.f. (° C) 783 -. 783 -CH3 -CH3 - -N0- ° - "dCF3 130.6-133.7 784 -. 784 -CH3 -CH3 - - -oCHCF3 146.6-147.6 788 -. 788 -CH, -CH 141-142 [Table 91] Example R1 f? G [Table 92] 798 -. 798 -CH3? and 132 - 133 802 -. 802 -CH3 ^ c oa0'cFs 123.8-125.3 [Table 93] [Table 94] Example Rl R2 R3 p.f.fCÍ _. SOS -CUj,? 4-CFs? Ph- 1S2.0-1B4.2. 810 -H -H -CFaOPI? - 148.9-148.7 [Table 95] Example Rl R2 p.f. (° C) 811 -CH3 4-CF3Ph- 226.0 - 227.6 Table 96] Example Rl R2. Cc 812 -CH3 4-CF3OPh- 209.0-212.0 813 -H 4-CF3OPh- 208.0-210.9 [Table 97] Example Rl 2 P-f- (° C) 814 -CH3-CgH5 195.0-196.5 815 -H -C8HS 232 dec 816 -. 816 -CH34-FPh- 209.0-209.5 817 -H 4-FPh- 228.0-231.0 818 -CH34-ClPh- 213.0-216.0 819 -H 4-ClPh- 243.0-246.0 dec 820 -. 820 -CH34-CF3Ph- 208.0-209.0 821 -H 4-CF3Ph- 208.0-211.0 822 -CH34-CF3OP - 203.0-204.9 823 -H 4-CF3OPh- 218.0-219.4 824 -CH33.4-C! 2Ph- 220.0- 221.0 825 -H 3,4-CtPh- 210.5-212.0 826 -CH3-NHC6H5 827 -H -NHC6H5 828 -CH34-CIPhCH2- 196-197.5 829 -H 4-CIPhCH2- 830 -CH34-CF3OPhCH2- 831 -H 4- CF3OPhCHz- [Table 98] Example The E2 H / = \ 840 -H; N-CHF: 841 -CH3 to- ^ ~ ^ -0-CF3 [Table 99] Example The E2 H3Q / == \ 843 -CH3 - N-¿-O 846 -CH3 -y ^ - ^ 221.4-223.6 848 -. 848 -CH3 -0 - ^^ - O-CF3 851 -. 851 -H ^ -0- [Table 100] Example Rl? £ 2 P.f. (° C) 852 -CH3 -C6H5 182.0-183.0 853 -H -C6H5 257.0-259.0 854 -CH3 4-CIPh- 202.3-205.2 855 -H 4-CIPh- 231.0-233.5 dec 856 -. 856 -Way 4-FPh- 230.5-233.0 857 -H 4-FPh- 215.0-217.5 858 -CH3 4-CF3Ph- 229.0-232.0 859 -H 4-CF3Ph- 179.0-182.0 860 -CH3 4-CF3OPh- 274.0-176.0 861 -H 4-CF3OPh- 185-188 862 -CH3 3,4-Cl2Ph- 206-208.5 863 -H 3,4-C! 2Ph- 190-193 864 -CH3 4-CF3OPhOCH2- 201.3-202.2 865 -H 4 -CF3OPhOCH2- 191.5-194.5 [Table 101] Example R2 p.f. t «3 CF, 867« CH3 LJOG * to 109.8-112.7 [Table 102] [Table 103] Example Rt Ra -f. fC) «71-CH5 -CgH5 249.3-250.0 872 -CHs 4-CIPh- 257.6-256.2 873 H -CbHs 248.2 -252.1 dec -H 4-ClPh- [Table 104] Example R1 R2 [Table 105] Example R1 R2 P-f- f C) S76 * CHj -CgH ^ 221.2-222.1 877 -CH5 4-CIPh- 229.6- 232.1 87S -H -CSHS 246-2-247.0 S7 & -H 4-CIPh- 260.4-260.9 [Table 106] Example Rl R2 R3 PfCC) 880 -CH3 -H -CßH5 144.0-146.3 881 -CH3 -H 4-CIPh- 1910-193.9 dec 882 -H -H -CSHS 883 -H -H 4-CIPh- 161.0-165.0 dec 884 -CH3 -CH3 -C6HS 121.0-126.1 dec 885 -CH3 -CH3 4-CIPh- 215.0-217.5 dec 886 -H -CH3 -C6HS 218.0-219.1 dec 887 -H -CH3 4-CIPh- 183.0-186.6 dec [Table 107] Example R R2 p.f. TO that -CHa 4 - ?? hC t? Ao.9-iB3.? 869 * CHs 4-CFaOphCHí- 1 Si .1-154,1 [Table 108] Example The E2 P.f. (° C) 890 -. 890-CH3, NCG ° uCFí 166.7-169.2 891 -. 891 -H X ° Cp3 139.8-141.6 894 -. 894 -CH3) X? A 197.0-199.3 895 -. 895 -H xracl 177.9-179.3 896 -. 896 -CH3 XX ^ 199.6-201.2 3 898 -. 898 -CH3 ¿s > «L0-CF3 210.9-212.0 899 -. 899 -H 188.0-190.0 [Table 109] Example Rl R2 p * CQ 900 -CH3 4-CIPh-238- -239 901 -CH3 4-CF3OP-199- -200 902 -CH3 4-CIP CH2- 199- -200 903 -CH3 4-CF3OPhCH2- 172- - 173 [Table 110] Example Rl R2 P-f. fC) -CHa 4-CIP ?? - 175.5- 176.5 90S -CHa 4-GFaGFh- 122.5-124 d? C [Table 111] Example R2 Cl ifif -CHs Q ^ - se? -H AyCr SOS 'CHs AyCr0'1 809 -. 809 -H A, £ * 1Q -CHS OO ^ 912 -. 912 -CHS / HQ-Q CF « £ H -CH, _! ~ ° - CF3 »" -H? ^ [Table 112] Example Rl 2 R3 m B5 Rβ EM (MH) 91S -CHj -tí -tí -CsHt, -H -H 526 919 -CHj -tí -H (CH3JaCOGO- 9S © -CHs • tí ^ H • COaCsHs -H -H 522 9S1 -CHj -CGHs -K -H -H -H 5! = 6 SS2 -CH. • H • H • OH -H -H 923 -CHj -H -t- -CJPfcQ- 576 [Table 113] Example R1 R2 EM (MH) [Table 114] Example Rl R2 E (M + 1) [Table 115] Example RI R2 R3 R4 m E CMÍ-13 943 -CHa -H -H OCHgCgHg -H -H 571 943 -CHS -H -K • cy or-CßH-p ^ H -H S47 944 -CHj -H? "QCgHfjr • H -H 593 945 CHS -H H • cyc [? - C3H§ -H -H 533 940 -CHS -H -H • H -OCeH s," H 557 [Table 116] Example fil R2 mm RB EM (* -1) 947 'CHa -H -H -Cl- tí -H 513 94S -OH; I. «1 -B -H -tí S13 S4ß -CH, 41 1 -CHtCHj) í -rt -t S21 351 -CH.J -H -H -C (CH:, b ^ H -ty 95 &-CHj -H -H -CF, -H ~ H 547 853- -CHJ -H -H- CH3 -H -H 493 954 »CHb -H • H -CM -H -H 504 SS &-CH, • H -H -O &Hs -H -H S5S 05B -CHJ -0CF3 • H -H -H- H be as? -CHs -H-CH3 • H • H -H sa ase -CHg -H -H -OCFg • H »HJ 563 855 -CHs -H -Cl -H -H -H 513 860 * CH > • M • H -F -H -H 497 so -CH ^ ^ H • OCH, • H -H -H SÜ9 &-CHs -H -Cl • Cl »H -B 547« is -CHj -GFj -H • H -H -H 547 ees -CHS +1 -OCÍJHJ 41 • H -H 571 9S -CMa -H -H -SCH;, -H -H 525 967 • CHa -H -ty -H -H -H 479 888 • GM-, -H- CF3 -H -H -H 5T3 sm -GH, -aH • F +1 -H S3I sm -CHg -H -Cl 41 -Cl -H 547 &71 -CHs- a -Ci 41 -tí • H 547 87 £ -CH3 -y "CH? 41 -CH3 -H S07 &7% -GiHg - -H -H • Cl -H S47 374 -CH3 - l -H -CsHs • H -H 60? [Table 117] Example RI Rg EM £ M- 977 -. 977-CH: 567 9B2 -CH-,. (CH? WH »507 - [Table 118] Example R2 EM M-Í * 1} 9S? »CB3 MM ^ S9S 990 -. 990 -OH, H h- - * 0 * S9Q [Table 119] Example R1 Rg R3 m ps Rfi EM flVH BSS - Hs -CHj -H -H • OCFa »H • H be daß -CHS -CHJ -H -HCF, -H -H S4§ 997 «CHs OH *» H 41"• CN • H * H 503 SS3 -CH3 -CHJ -H -H -N04 -M -H W? 9S9 -CHa • CHJ. • H • H • NtCHJa • H • H 521 IODO -CH8 -CH -GCF, -H -H -H -H £ 26 1001 -. 1001 -FHI, -CHi -H -OCf -H -H -H 59S icoa -CH3 -CHi -H -H -SCfeN < CH, ¡) »-H -H s 1003 -. 1003 -CHs "CHJ. -H -H • O ÍBJ -H • H 5SQ 1004 -. 1004 -CH., -GH, -H ~ C ^ -H -H -H 546 1005 ^ CHa • CHJ -H -C -01 -H -H 5 «5 «OS -CHs -cu, -H -H -CHp -H -H 492 1O07 -CHa -CHj -H -H -e-a- a -H -H S34 1008 -. 1008 -CH3 -CH? -CF, -H -H -H ^ H S4ß 0013 -CHS -OH $ -Cl -ct -H -H -H46 »-CH, -CHj -H -H -SCH3 -H -H 524 1011 -. 1011 -CHj -CHa -H -tt -CH. { CHak -H -H 520? O? A -CHj -H -H -OCsHt -H -H 570 t013 -CHj -CHa -H -H -OOJHJS -H -H 573 1014 -. 1014 -CH5"CMa -B 41 - jHu • H • H 562 «.15 -CHs -CHJ -H -H -OCH Hs -H -H S84 1016 -. 1016 -CHj • CHa • Cl -11 • Cl • H • H 54 © 1017 -. 1017 -CHj -CHa -tí -Cl -Cí -H - saa 1018 -. 1018 -CHs • CBa • Cl -H -H -tt -t 512 1019 -. 1019 -CHj -CHJ -H -H -OCH5 -H -H sos @ 3 »€ H -CH -tt -Cl -0 -H -H 546 icex -CH, -GHa -H -H -OCHFÍ -H -H 544 1G22 -CHj -CH ^ -H¡ - & -H -H SSQ 1G23 -CH, -GH. 41 • H 41 41 561 0 laña -CHa -CHS -H -CH3 -Cl -H -H 58S 1D25 -CHj -OH. -H -H Ai -H -H 54S [Table 120] Example R1 R2 R3 R4 is R8 R7 EM (M + 1 > 1027 -. 1027 -CHS -CH3 4f .H -O1 -H -H 1028 -. 1028 -CH3 -CH3 -H ~ H -CHaCcHis -H -H «is 1029 -. 1029 -CH3"CHs -H -H -H -ty 591 1030 -. 1030 -CHs - Ha -H »H Q- - ^ -H 1031 -. 1031 -CHS -CH # -H -CJ -H -H -H 51 to 103 * 5. -CH9 -CHa -H -H -CgHj -H -H 554 [Table 121] Example R1 2 R3 EM (frM) 1034 -. 1034 -CHa -CH. xo 536 10S & -CH3 -CHa iTj ^ 522 1040 -. 1040 -CH3 -CH5 or 529 , 4, -CH, -CH »56S [Table 122] Exemplary FH ra R5 EM ÍM + D 1042 'CHj • H • H -H • OCH. • H 500 ÍS43 -CH, -H -H -OCH5 -H -H 5Ú9 1044 -. 1044 -CHj -H -OCHs -OCHJ -H -t 539 1045 • CHJ • H • H 41 41 41 479- 1046 -CHT • a • H • H • H • H if a 1047 -. 1047 -CHT -H -Ci -H -H -H 513 * 15 -CH ,, -B -H -Ct -H -H 513 toso -CH. -H -H -CHj -H -t 493 test -CH, -H -H -cu, -H SO? 1052 -. 1052 -CHj -tt • H -F -H -Hr 1053 -. 1053 -CH. + f • H -CC iCiH »41 4i 551 10S4 -CH, -H -H -C4 41 • H S04 1055 -. 1055 -. 1055 -. 1055 -CHj: -CF5, -H -H -H-547 105S -CH, • H -CF3 • H • H -H 547 IOS? -QH3 -H -H -CF. -H -H S47 1055 -C "-OCF; -H -H -H -H = 63 101 © - W? • tt • OCFs • H -H -H 10ßS -CHa -O or -H -H ^ S4ß 10É3 -OH, -OCHfCHife -H -H • H • H 537 1064 -. 1064 -CHj -F -H -H -CH3 -H 5Í1 W $ »CHj -H -F -Cf -H -H .CHs -F -B -N06 -H -H S? 2 1067 -. 1067 -CHr -OCH • H -CHi HhtS i -H -H 1064 »CH3 41 • Kt iHík -H -H 1069 -CH_ -OCA -H -HCH * .CHCH, (cia -H [Table 123] Elemplß | 2. R3 _ _ R5 JFS5 IMftWQ 1070"CH" "-H-1-CHiCH") »1 -H 1071 -CH» 43 41 H; HfC? CH 1 41 107 ?. -CHf -H -NHGiH, 41 -H -H 1073 -CHj 41 -H -GH * C0ÍCKÍ -H 41 10f? 4 -CHj * C1 -H .Coilj "H 41 107S -CU, 4t 41 -COCaHj * H 4? í? m -CHj, -H -CH3 -Cfk -GHJ -H? < J? 7 -CHs -t? -H 'CHj -H -H toso • CHj • H 41 • OOH • Hs -H 41 58 $ 1C € £ • CHj * $ **] 41 -.cycle »C * H», * f 41 561 IOSS -CHj -H -H 'QC its -H -H S§7 \ ÜM -CHJ -H 41 • CÍCl? .CsHs 41 -K «10B5 * CMI -tt -OCA 4 • H 171 1055 -OHj -B -H • Ch! • H -H 583 [Table 124] Example RÍ EM < M *?) Wm -QHa I 529 [Table 125] Example R1 Rí n -CH, X Example 1098 (R) -2-methyl-2- (4- (N-methyl-N- (l-methylpiperidin-4-yl) amino) phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1- b] oxazole Example 1099 (4-trifluoromethoxyphenyl) amide of (R) -4- (1- (4- (2-methyl-6-nitro-2,3-dihydro-imidazo [2, 1-b] oxazole -2 -ylmethoxy) phenyl) -3- (4-trifluoromethoxy-enyl) ureido) -piperidine-1-carboxylic acid Example 1100 6-Nitro-2- (4- (4- (4-trifluoromethylbenzyloxymethyl) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole Melting point: 140.2-141.7 ° C.

Example 1101 (R) -2-methyl-6-nitro-2- (4- (4- (tetrahydropyran-2-yloxymethyl) piperidin-1-yl) phenoxymethyl) -2, 3-dihydroimidazo [2, 1-b] oxazole Melting point: 217.6-218.6 ° C.

Example 1102 (R) -2-methyl-6-nitro-2- (4- (4- (hydroxymethyl) piperidin-1-yl) phenoxymethyl) -2, 3-dihydroimidazo [2, 1-b] oxazole Example 1103 2-methyl-6-nitro-2- (4- (4- (4-trifluoromethoxyphenoxy) piperidin-1-yl) benzyl) -2,3-dihydroimidazo [2, 1-b] oxazole Melting point: 184.9 -186.8 ° C.

Example 1104 (R) -2-methyl-6-nitro-2- (4- (4- (4-trifluoromethoxyphenyl) carbamoyloxymethylpiperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole Melting point: 211. 6 ° C-212. 0 ° C (decomposition) Example 1105 (R) -2- (4- (4- (biphenyl-4-yloxymethyl) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b ] oxazole Melting point: 245 ° C (decomposed) Example 1106 (R) -2- (1-Benzyl-2- (4- (4-trifluoromethoxybenzyl) piperazin-1-yl) -lH-benzimidazol-5-yloxymethyl) -2 -methyl-6-nitro-2, 3-dihydroimidazo [2, 1-b] oxazole Melting point: 101.3 ° C-104.0 ° C Example 1107 (R) -2-methyl-6-nitro-2- (4- (4- (4-trifluoromethoxybenzyl) piperidin-1-ylmethyl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole Melting point: 172.5 ° C-174.1 ° C Example 1108 2- (4- (4 - (N-Methyl-tert-butoxycarbonylamino) piperidin-1-ylmethyl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole Melting point: 138.5 ° C-141.9 ° C Example 1109 (R) -2- (4 '- (4-tert-butoxycarbonyl-1,4-diazepan-1-yl) biphenyl-4-yloxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole Melting point: 213.8 ° C-215.7 ° C Example 1110 (R) -2- (4'- (4-tert-butoxycarbonyl-l, 4-diazepan-l-yl) biphenyl-4-yloxymethyl) -6-nitro -2, 3-dihydroimidazo [2, 1-b] oxazole Melting point: 235.5 ° C-237.5 ° C Example 1111 (S) -2-methyl-2- (N-methyl-N- (4- (N- methyl-N- (4-trifluoromethyl-acyl) amino) benzyl) aminomethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole Melting point: 153.5 ° C-154.5 ° C Example 1112 (R) -2-methyl-6-nitro-2- (4- (2-oxo-2- (4- (4-trif luoromethoxy-enoxy) piperidin-1-yl) ethylaminocarbonyl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole Melting point: 186.9 ° C -189.5 ° C Example 1113 2-methyl-6-nitro-2- (2- (4- (4-trifluoromethoxybenzyl) piperazinyl) benzothiazol-6-yloxymethyl) -2, 3-dihydroimidazo [2, 1-b] oxazole Melting point: 172.6 ° C-174.6 ° C Example 1114 2- (4- (4- (4-chlorophenoxymethyl) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2 , 1-b] oxazole Melting point: 190.0 ° C-190.4 ° C Example 1115 2- (4- (4- (4-chlorophenoxymethyl) piperidin-1-yl) phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole Melting point: 191.2A-192.5 ° C Example 1116 6-Nitro-2- (4- (4- (4-trifluoromethoxybenzyl) piperidin-1-yl) phenoxymethyl) -2, 3- dihydroimidazo [2, 1-b] oxazole Melting point: 132.7 ° C-135.0 ° C Example 1117 2-methyl-6-nitro-2- (4- (4- (4-trifluoromethoxycinnamyl) piperazin-1-yl) phenoxymethyl ) -2, 3-dihydroimidazo [2, 1-b] oxazole Melting point: 181.1 ° C-182.2 ° C [Table 126] Example R1 R2 R3 R4 R5 R6 P.f. (0C) 1118 -CH 3 -H -H -Br -H -H 207.1-208.9 1119 -CH 3 -H -H -Cl -Cl -H 204.7-206.4 1120 -CH 3 -H -H -CH 3 -H -H 210.4- 211.9 1121 -CH3 -H -H -OCF3 -H -H 213.0-214.9 1122 -CH3 -H -H -Cl -H -H 198.6-201.2 1123 -H -H -HF3 -H -H 172.1-174.7 1124 -H -H -HCl -H -H 179.6-181.5 1125 -H -H -Cl -Cl 41 -H 189.1-190.7 1126 -H -H -H -Br -H -H 202.6-204.4 1127 -CH3- H -H-OCH3 -H -H 218.5-220.6 1128 -H -H -OCF3 -H -H 181.1-182.7 1129 -CH3 -H -Cl -H "H -H 195 dec 1130 -CH3 -H -CF3 -H -CF3 -H 183 dec 1131 -CH3 -H -CF3 -Cl -H -H 196.1-197.4 1132 -CH3 -H -CF3 -F -H -H 210.5 dec 1133 -CH3 -Cl -Cl -H -H -H 212 dec [Table 127] Example R1 R2 R3 R4 R5 R6 Pf- (° C) 1134 -H -H -H 4-CIPH -H 245-248 1135 -CH3 -H -H 4-CIPh- -H -H 241.7-243.5 1136 -CH3 -H -H -CßHs -H -H 254.6-258.0 1137 -H -H -H 4-CIPh? -H-184.7-187.9 1138 -CH3 -H -H 4-CIPh? -H 179.2-181.8 1139 -H -H -HCBH5 -H -H 256.0-258.2 [Table 128] Example 1 R2 R3 R4 R5 R6? NMR 1140 -CHa -H -H 4-CF3Ph- -H -H 'HRiyiNi-CDCI; ») d 1.75 (3H, s), 2.52- 2.74 (4H, m), 2.99-3.22 (4H, m), 3.62 (2H, S), 3.92-4.09 (2H, m), 4.17 (1H, dlJ = 10.2Hz), 4.48 (1H, dIJ = 10.2Hz), 6.66-6.82 (2H, m), 6.82-6.94 (2H , m), 7.43 (2H, d, J = 8.2Hz) I7.50-7.61 (3HIm), 7.69 (4H, s). 1141 -CH3 -H-4-CF3OPh-H-1HRryiN (CDCl3) d 1.76 (3H, s), 2.49- 2.74 (4H, m), 2.97-3.22. { 4H, m), 3.61 (2H, s), 3.89-4.10 (2H, m), 4.17 (1H, d, J = 10.2Hz), 4.49 (1H, d, J = 10.2Hz), 6.68-6.81 ( 2H, m), 6.81-6.95 (2H, m), 7.28 (2H, d, J = 8.6Hz), 7.43 (2H, d, J = 8.2Hz), 7.48- 7.67 (5H, m). 1142 -H -H -H 4-CFaPh- -HH 1HRMN (CDC! 3) d 2.51-2.76 (4H, m), 3.00-3.24 (4H, m), 3.62 (2H, s), 4.14- 4.53 (4H, m), 5.47-5.68 (1H, m), 6.68-6.97 (4H, m), 7.44 (2H, d, J = 8.2Hz), 7.51-7.62 (3H, m), 7.62-7.80 (4H , m). 1143 -H -H -H 4-CF3OPh- H -H 'HRMN (CDCI3) d 2.53-2.73 (4H, m), 3.02-3.21 (4H, m), 3.57 (2H, s), 4.15-4.50 (4H , m), 5.49-5.66 (1 H, m), 6.72-6.95 (4H, m), 7.28 (2H, d, J = 2Q.1Hz), 7.43 (2H, d, J = 8.2Hz), 7.52 ( 2H, d, J = 8.3Hz), 7.56-7.67 (3H,).

[Table 129] Example »R1 R2 P-f, (° c) 1144 -. 1144 -CH3 4-CIPhCOCH2- 211 ^ 212 1145 -. 1145 -CH3 4-CF3PhCOCH2- 197-198 1146 -. 1146-CHg (CH3) 3COCONH- 254.1-255.9 1147 -. 1147 -CHg 4-CF3OP COCH2- 200-202 1148 -. 1148 -CH3 4-CF3PhCH2N (CH3) - 201.1-203.7 1149 -. 1149-CHg 4-CF3OP CH2N (CH3) -. 208.9-210.3 1150 -. 1150 -CH3 4-CIPhNHCH2CH2- 172-173 1151 -. 1151 -CH3 4-CF3? PhNHCH2CH2- 161-162 1152 -. 1152 -CH3 4-CIPhN (CH3) CHzCH2- 179-180 1153 -. 1153 -CH3 4-CIP CH2N (CH3) - 204.8-205.5 1154 -. 1154 -CH3 4-CF3? PhN (CH3) CH2CH2- 141-142.5 1155 -. 1155 -CH3 4-CF3PhNHCH2CH2 »- 159-160 1156 -. 1156 -CH3 4-CF3PhN (CH3) CH2CH2- 177-178 1157 -. 1157 -CHg PhC = CCH2- 186.0-189.0 [Table 130] [Table 131] [Table 132] Example < D R1 F12 R3 R4 R5 R6 R7 P.f. (° C) 1175 -CH 3 -CH 3 -CF 3 -H -CF 3 -H -H 176.7-178.3 1176 1 -CH 3 -CF 3 -H -CF 3 -H -H 135.7-137.6 1177 -CH 3 -CH 3 -H -H 4- CF3Ph- -H -H 226.0-229.3 1178 -CH3 -CH3 -H -H 4-CIPh- -H -H 244.2-246.9 1179 -CH3 -CH3 -H 41 4-CIPhO- -H -H 189.5-194.1 1180- CH3 -CH3 -H-4-CF3OPhO- -H -H 200.0-203.5 1181 -H -CH3 -H -H 4-CIPh- -H -H 237.4-239.0 1182 44 -CH3 -H -H 4-CF3OPh- -H -H 215.8-218.7 1183 -H -H -H 4-CF3OPh- -H -H 233.7-235.8 1184 -CH, -H -H -CBHS -H -H 241.2-243.7 1185 -CH3- CH3 -H -H -C6HS -H -H 227.2-229.5 1186 -H -CH3 -H -H -CgHs -H -H 229.8-231.7 1187 -H -H -H -H -CaHs -H -H 248.4 -253.6 [Table 133] Example R1 R2 R3 R4 R5 R6 R7? NMR 1188-CH 3 -H-4-CF 3OP-H-1 H NMR (CDCl 3) d 1.65-2.06 (7H, CH3 m), 2.26 (3H, s), 2.47-2.77 (3H, m), 3.51-3.72 (4H, m), 3.92-4.09 (2H, m), 4.17 (1H, d, J = 10.2Hz) , 4.49 (1 H, d, J = 10.2Hz), 6.66-6.82 (2H, m), 6.82-6.97 (2H, m), 7.27 (2H, d, J = 6.9Hz), 7.40 (2H, d, J = 8.2Hz), 7.46-7.66 (5H,). 1189 -H-CH3 -H -H 4-CF3Ph- -H -H 1 H NMR (CDCl 3) d 1.70-2.06 (4H, m), 2.30 (3H, s), 2.44-2.78 (3H, s), 3.48 -3.75 (4H, m), 4.17-4.53 (4H, m), 5.48-5.70 (1H, m), 6.71-6.85 (2H, m), 6.85-6.98 (2H, m), 7.42. { 2H, d, J = 8.2Hz), 7.51- .61 (3H, m). 7.72 (4H, s).

[Table 134] 1191 -. 1191 -CH3 -H 185.0- 188.8 [Table 135] Example R1 R2 P-f-fC) 1192 -CH3 -CH3 252-255 dec. 1193 -CH3 4-CF3PhCH = CHCH2- 232-234 1194 -CH3 4-CIPhCH * = CHCH2-231-232 1195 -CH3 4-CF3OPhCH = CHCH2-228-230 [Table 136] Example R1 R2 R3 D.f.fC) 1196 -CH3 4-CF3Ph- -CH3 188-195 dec. 1197 -H 4-CF3Ph- -CH3 172-174 1198 -CHg 4-CF3OPh- -C2HS 196.5-198 1199 -CH3 4-CIPh- -C2H5 184.5-186.5 1200 -CH3 -CH3 -CH3 250-252 [Table 137] EiempIo R2 R3 R4 R5 R6 o.f, (° C) 1201 -. 1201 -H -H -H 4-CF3Ph- -H -H 196.0-198.2 1202 -. 1202 -CH3 -H -H 4-CF3OP - -H -H 229.4-230.1 1203 -. 1203 -H -H -H 4-CFgOPh- -H -H 185.7-187.2 1204 -. 1204 -CH3 -H -H 4-CÍPh- -H -H 248.9-250.0 1205 -. 1205 -H -H -H 4-CIPh- -H -H 236.2-238.8 1206 -. 1206 -CH3 -H -H -C6HS -H -H 224.2-227.4 1207 -. 1207 -H -H -H -C6H5 -H -H 235.8-237.4 [Table 138] Example R1 R2 R3 R4 R5 R6? RN 1208 -CH, -H -H 4-CF3Ph- -H -H 1 H NMR (CDCl 3) d 1.30-1.54 (2H, m), 1.58-1.98 (6H, m), 2.44-2.72 (4H,), 3.36 - 3.62 (2H, m), 3.91-4.08 (2H, m), 4.16 (1H, d, J = 10.2Hz), 4.48 (1H, d, J = 10.3Hz), 6.66-6.81 (2H, m ), 6.81-6.94 (2H, m), 7.18-7.32 (2H, m), 7.44-7.59 (3H, m), 7.61-7.75 (4H, m).

[Table 139] Example R1 R2 P.f- C) 1209 -CH3 -CH2OCH3 194.0-195.6 1210 -CH3 -H 216.8-218.4 dec. 1211 -H-CH2OCH3 150.0-151.2 [Table 140] Example R1 R2 p.f, (C) 1212 -CH3 -CH2OCH2OCH3 208.7-210.7 1213 -CH3 -CH2OH 171.0-173.8 1215 -. 1215-CH3 CH3 166.0-166.9 1216 -. 1216-CH3 CH3 196.9-200.3 [Table 141] R1 R2 p.f. DC) 1217 -. 1217 -CH3 3,4-Cl2PhCH = CHCH2- 202.4-203.5 1218 -. 1218 -CH3 4-C] PhCH = CHCH2- 196.0-199.4 1222 -. 1222-CH3 192.2-195.3 'xvO ° & 1223 -CH3 182.2-183.5 ^ OjO "1224 -CH3 219.6-221.9 H ^ [Table 142] Example R1 R2 R3 P-f. (° C) 1225 -CHa - -CwH? i3 203.4-205.0 1226 -. 1226 -CH3 -CHa 187.7-190.0 1227 -. 1227 -H-CHa 213.1-214.5 1228 -. 1228 -H -CH, 212.6-214.4 1229 -. 1229 -H-CH3 206.5-207.7 [Table 143] Example R1 R2 R3? NMR 1230 -H-CH3 CH, 1HR N (CDCl3) d 1.46 (9H, s), 1.54-CH, 1.84 (4H, m), 2.57-2.85 (6H, m), 3.39- ~ "¿H 3.65 ( 1 H, m), 4.04-4.52 (7H, m), 5.49- 5.67 (1 H,), 6.69-6.86 (4H, m), 7.58 (1 H, s).

[Table 144] Example R1 R2 P.f- CC) 1231 -CHg 4-CF3OPhCH2- 164.6-167.5 1232 -CHa 4-CF3OPhCH * = CHCH, -155.8-158.5 [Table 145] Example R1 R2 P.f. (° C) 1233 -CH3 4-CIPhS- 182.8-184.6 1234 -CH3 4-CF3OPhS- 147.2-150.0 1235 -CH3 4-CIPhSO2- 223.5-224.9 1236 -CH3 4-CF3OPhSO- 128.0-130.7 1237 -CH3 4-CF3OPhSO2 - 171.2-174.1 [Table 146] 1239 -. 1239 -CH3 -H 231.4-234.1 1240 -. 1240 -CH3 -CH3 133.9-134.9 [Table 147] [Table 148] 1245 -. 1245 -CH3 265.0-266.5 AVO-CI 1249 -. 1249 -CH3 178.1-179.6 1250 -CH3 190.0-191.5 1251 -CH3 -too 175 dec ^ [Table 149] 1256 -. 1256 -CHa 206.4-209.7 [Table 150] [Table 151] 1262 -. 1262-CH3 158.8-161.4 S * [Table 152] [Table 153] 1271 -. 1271 -H rc v 198.8-200.9 1273 -. 1273-CHg -Cl 182.2-184.7 1276 -. 1276 -CH3 237.9-239.9 [Table 154] [Table 155] Example R1 R2 p.f. (C) 1280 -CH3 4-CF3PhCH2- 201.2-202.0 1281 -. 1281 -CH3 4-CIP CH2- 194.4-195.7 1282 -. 1282 -CH3 4-CF3PhCH = CHCH2- 184.2-186.7 1283 -. 1283 -CH3 4-CF3OP - 256.1-258.7 1284 -. 1284 -H 4-CFgOPh- 254.6-255.6 1285 -. 1285-CHg 4-CF3Ph- 270.6-271.6 1286 -. 1286 -H 4-CFgPh- 256.8-259.5 [Table 156] Example R1 R2 P.f. (° C) 1287 -CH3 4-CF3OP O- 223.8-225.6 1288 -. 1288 -CH3 4-CF3OPhCH2- 168.3-171.2 1289 -. 1289 -CH3 4-CIPhN (C2H5) - 119.9-122.0 1290 -. 1290 -H 4-CF3PhO- 199.7-202.0 1291 -. 1291 -CH3 4-CIP N (CH3) - 147.8-150.7 1292 -. 1292 -H 4-CIPhN (CH3) - 128.4-130.9 [Table 157] 1294 -. 1294 -CH3 - 210.2-211.4 1296 -. 1296 -CH3 143.2-145.1"^ [Table 158] Example R1 R2 p.f. (° C) 1297 -CH3 4-CF3Ph- 252.5-255.6 1298 -. 1298 -CH3 4-CF3OPh- 242.7-243.1 1299 -. 1299 -H 4-CF3OPh- 1300 -CHa 136.6-139.0 .O L0 1301 -. 1301 -CH3 rc M 138.6-141.3 1304 -. 1304 -CH3 196.8-199.3 1305 -. 1305 -H C 1H, * 176.4-179.4 crxx [Table 159] Example R1 R2 p.f.rc) 1306 -CH3 4-CF3OPhCH2- 151.1-154.1 1307 -CH3 4-CIPhCH2- 180.9-183.1 1308 -CH3 4-CF3OPh- 190.4-192.8 [Table 160] 1310 -. 1310 -CH3 225.4-226.9 1311 -. 1311 -H 188.5-191.0 -O or »[Table 161] 1313 -. 1313 -CH3 132.4-134.7 [Table 162] Example R1 R2 p.f. (° C) 1314 -CH3 4-CF3PhCH = CHCH2- 152-153 1315 -. 1315 -CH3 4- (4-CF3OP O) PhCH2- 127.4-129.2 1316 -. 1316 -CH3 4-CF3OPhO (CH2) 2- 121.6-122.2 1317 -. 1317 -CH3 4-CIP O (CH2) 2- 121.8 dec 1318 -. 1318 -CH3 3,4-CI2PhO (CH2) 2- 96.5-98.2 [Table 163] [Table 164] 1326 -. 1326 -CH3 229.4-232.0 [Table 165] ExampleRI R2 R3 R4 R5 R6 EM (M + 1) 1328 -. 1328 -CH 3 -H -H -OCHg -Cl -H 543 1329 -CH 3 -H -H -CHg -CH 3 -H 507 1330 -CH 3 -H -H -OCH CgH 5 -H -H 585 1331 -CH 3 -CH 3 -H -CHg -H-CH3 521 1332 -CH3 -CHg -H-CH3 -CHg -H 521 1333 -CH3 -H -H -CH = CHC6H5 (trans) -H -H 581 [Table 166] Example R1 R2 EM (M + D 1334 -CH3 480 1338 -. 1338 -CH3 co 523 1341 -. 1341 -CH3 to 480 [Table 167] [Table 168] Example DR1 R2 E (+1) 1345 -. 1345 -CH3 4-CH3OPh- 578 1346 -CH3 4-CIP-582 1347 -CH3 3,4-Cl2ph- 616 1348 -CH3 4-CF3Ph- 616 1349 -CH3 4-CF3OPh- 632 1350 -CH3 4-ClPhCHa- 596 1351 -CH3 4-CF3PhCH2- 630 1352 -CH3 4-CH3PhCH2- 576 1353 -CH3 4-CF3OPhCH2- 646 1354 -CH3 3-CH3OPhCH2-592 1355 -CH3 3, ^ yshCH 630 [Table 169] Example R1 R2 EM (M + 1) 1356 -CH3 4-CIPh- 567 1357 -CH3 4-CH3OPh- 563 1358 -CH3 4-CF3Ph- 601 1359 -CH3 4-CH3Ph- 547 1360 -CH3 3,4-ClaPh- 601 1361 -CH3 4-CF3OPh- 617 [Table 170] Example R1 R2 E (+1) 1362 -. 1362 -CH3 4-CH3OP-592 1363 -CH3 4-CIPh- 596 1364 -CH3 3,4-CI2Ph- 630 1365 -CH3 4-CH3Ph- 576 1366 -CH3 4-CF3Ph- 630 1367 -CH3 4-CIP CH2- 610 1368 -CH3 4-CF3PhCH2- 644 1369 -CH3 4-CF3OPhCH2- 660 1370 -CH3 3-CH3OPhCH2- 606 1371 -CH3 3,4-CI2PhCH2- 644 [Table 171] Example R1 R2 E (+1) 1372 -CH3 4-CIP-581 1373 -CH3 4-CF3Ph- 615 1374 -CH3 4-CH3Ph- 561 1375 -CH3 3,4-CI2Ph- 615 1376 -CH3 4-CF3OPh- 631 [Table 172] Example R1 R2 R3 EM (M + 1) 1377 -CH3 -CH3 4-CF3OPh- 645 1378 -CH3 -CH3 4-CF3Ph- 629 1379 -CH3 -CH3 4-CH3Ph- 575 1380 -CH3 -CH3 3,4-Cl2Ph - 629 [Table 173] 1383 -. 1383 -CH, -CH «3 643 [Table 174] -CH3 -CH3 572 CL -CH3 -CH3 538 ^ ya [Table 175] 1395 -. 1395 -CH3 - C / Hl-lg 568? " [Table 176] Example R1 R2 EM (M + 1) 1403 -CH3 4-CF3PhCH = CHCH2-545 1404 -CH3 3,4-CI2P CH = CHCH2-545 1405 -CH3 4-CIPhCH = CHCH2- 511 1406 -CH3 4-CF3OPhCH = CHCH2 - 561 1407 -CH3 4-CF3OPhO (CH2) 2- 565 1410 551 a 1412 -. 1412 -CH3 518 -a [Table 177] [Table 178] Example R1 R2 EM (M + 1) 1425 -CH, 507 1429 -. 1429 -CH, 474 1434 -. 1434 -CHa 497 rt a [Table 179] 1438 -. 1438-Cl Cl 481 s- & 1440 -. 1440-CHg 521 [Table 180] Example > R1 R2 R3 R4 R5 R6 EM (M + 1) 1441 -. 1441 -CHg -H -H -OCHg -H -H 517 1442 -CHg -H -H -CH3 -CH3 -H 515 1443 -CH3 -H -H -F -H -H 505 1444"CHg -H -H- CF3 -H -H 555 1445 -CHg -H -H -CHg -H -H 501 1446 -CHg -H -H -Cl -Cl -H 555 1447 -CHg -H -H "OCFg -H -H 571 1448 - CHg -H -H 4-CJPhO- -H -H 613 [Table 181] Example R1 R2 EM (+1) 1449 -CH3 4-CH3OP-516 1450 -CH3 3,4-CI2PhCH2- 568 1451 -CH3 3,4-Cl2PhCH20- 584 1452 -CH3 4-CH3P CH20- 530 1453 -CH3 4-CF3OPhCH20-600 1454 -CH3 4-C! PhCH20- 550 [Table 182] Example 1463 (R) -2- (4- (4- (4-chlorophenyl) oxazol-2-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole 1.73 g (7.9 mmol) of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole, 1.80 g (6.6 mmol) of 4- (4- (4- chlorophenyl) oxazol-2-yl) phenol, and 0.42 g (2.0 mmol) of potassium phosphate were suspended in 15 ml of ethanol, and the mixture was heated under reflux with stirring for 3 hours under an argon atmosphere. The reaction solution was concentrated, and dichloromethane was then added to the residue to precipitate a non-soluble product, which was then completely filtered. The filtrate was concentrated, and the residue was dissolved in 20 ml of DMF to give a solution. 0.29 g (7.3 mmol) of 60% sodium hydride was added to the solution while cooled by ice, and the obtained mixture was stirred for 6 hours. After the solvent was removed under reduced pressure, and 100 ml of acetone and 10 ml of silica gel were added to the residue, followed by concentration. The residue was purified by silica gel column chromatography (dichloromethane: methanol = 50: 1 to 30: 1), and the resulting product was crystallized from a mixed solvent consisting of dichloromethane and ethanol. The resulting product was then recrystallized from a mixed solvent consisting of acetone and water to obtain 1.15 g (yield: 38%) of light brown powders, (R) -2- (4- (4- (4- chlorophenyl) oxazol-2-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 248.8 ° C-251.5 ° C Example 1464 6- ((R) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazol-2-ylmethoxy) -2- ( 4- (4-trifluoromethoxybenzyl) iperidin-1-yl) quinoline 0.65 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-i idazole, 1.00 g of 6 -hydroxy-2- (4- (4-trifluoromethoxybenzyl) piperidin-1-yl) quinoline, and 0.16 g of potassium phosphate were suspended in 10 ml of ethanol, and the mixture was heated under reflux with stirring for 4 hours in a argon atmosphere. The reaction solution was concentrated, and the residue was purified by silica gel column chromatography (from hexane: ethyl acetate = 1: 3 to ethyl acetate). The resulting product was concentrated, the residue was then dissolved in DMF (10 ml), and 99 mg of sodium hydride was then added thereto. The mixture was stirred at room temperature for 1 hour. Subsequently, water was added to the reaction solution and the extraction was repeated then carried out with ethyl acetate. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then dried over sodium sulfate. The sodium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (hexane: ethyl acetate from 1: 1 to 1: 3). The resulting product was recrystallized from ethanol to obtain 0.57 g (yield: 36%) of light yellow powder crystals, 6- ((R) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazol-2-ylmethoxy) -2- (4- (4-trifluoromethoxybenzyl) piperidin-1-yl) quinoline. Melting point: 184.9 ° C-185.9 ° C Example 1465 6- ((R) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazol-2-ylmethoxy) -2- (4- (4-trifluoromethoxybenzylidene) piperidin-1-yl) quinoline 0.66 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) ) -4-nitro-lH-imidazole, 0.94 g of 6-hydroxy-2- (4- (4-trifluoromethoxybenzylidene) -piperidin-1-yl) quinoline, and 0.15 g of potassium phosphate were suspended in 10 ml of ethanol , and the mixture was heated under reflux with stirring for 6 hours in an argon atmosphere. The reaction solution was concentrated, and the residue was purified by silica gel column chromatography (from hexane: ethyl acetate = 1: 3 to ethyl acetate). The resulting product was concentrated, the residue was then dissolved in DMF (10 ml), and 99 mg of sodium hydride was then added thereto. The mixture was stirred at room temperature for 3 hours. Subsequently, ethyl acetate was added to the reaction solution, and the mixture was then concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: methanol = 50: 1). The resulting product was recrystallized from ethanol to obtain 1.37 g (yield: 51%) of yellow powder crystals, 6- ((R) -2-methyl-6-nitro-2,3-dihydroimidazo [2.1] -b] oxazol-2-ylmethoxy) -2- (4- (4-trifluoromethoxybenzylidene) piperidin-1-yl) quinoline. Melting point: 193.9A-195.9 ° C Example 1466 (R) -2-Methyl-6-nitro-2- (6- (4- (4-trifluoromethoxyphenoxy) piperidin-1-yl) naphthalene-2-yloxymethyl) - 2, 3-dihydroimidazo [2, 1-b] oxazole 2.12 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole, 3.02 g of 6- ( 4- (4-trifluoromethoxyphenoxy) piperidin-1-yl) naphthalene-2-ol, and 0.48 g of potassium phosphate were suspended in 30 ml of ethanol, and the mixture was heated under reflux with stirring for 6 hours in an atmosphere of nitrogen. Subsequently, water was added to the reaction solution, and the repeat extraction was carried out with dichloromethane. The combined organic layer was washed with a saturated aqueous solution of sodium chloride and then dried over anhydrous magnesium sulfate, followed by concentration. The residue was purified by silica gel column chromatography (from hexane: ethyl acetate = 1: 3 to ethyl acetate). The resulting product was concentrated to obtain 2.73 g of yellow powders. The obtained powders were dissolved in DMF (27 ml), and 0.21 g of sodium hydride was then added thereto, followed by stirring at room temperature for 2.5 hours. Subsequently, a saturated aqueous solution of sodium chloride was added to the reaction solution, and the extraction was repeated then carried out with dichloromethane. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then dried over anhydrous magnesium sulfate. The magnesium sulfate was filtered, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate = 4: 1). The resulting product was recrystallized from a mixed solvent consisting of dichloromethane, ethyl acetate, and diisopropyl ether to obtain 1.05 g (yield: 24%) of light yellow powder crystals, (R) -2-methyl- 6-Nitro-2- (6- (4- (4-trifluoromethoxyphenoxy) piperidin-1-yl) naphthalene-2-yloxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 204.8 ° C-207.9 ° C Example 1467 (R) -2-methyl-6-nitro-2- (4- (4- (4-trifluoromethoxybenzyloxy) piperidin-1-yl) phenoxymethyl) -2, 3 -dihydroimidazo [2, 1-b] oxazole 0.305 g of 4- (4- (4-trifluoromethoxybenzyloxy) piperidin-1-yl) phenol was dissolved in DMF (5 ml), and 10 mg of sodium hydride was added thereto , followed by stirring at 70 ° C to 80 ° C for 20 minutes. Subsequently, 0.252 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole was added to the reaction solution while cooled by ice, followed by stirring at 70 ° C at 80 ° C for 20 minutes. Subsequently, the reaction solution was cooled to room temperature. Water was added to the reaction solution, and the repeat extraction was carried out with ethyl acetate. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then dried over sodium sulfate. The sodium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (from hexane: ethyl acetate = 1: 3 to ethyl acetate). The resulting product was recrystallized from a mixed solvent consisting of dichloromethane and ethyl acetate to obtain 88 mg (26.7%) of colorless powder crystals, (R) -2-methyl-6-nitro-2- (4- (4- (4-trifluoromethoxybenzyloxy) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 214.3 ° C-217.7 ° C Example 1468 (R) -2-methyl-6-nitro-2- (4- (4- (4-trifluoromethylbenzyloxy) piperidin-1-yl) phenoxymethyl) -2, 3 -dihydroimidazo [2, 1-b] oxazole 0.217 g of 4- (4- (4-trifluoromethylbenzyloxy) piperidin-1-yl) phenol was dissolved in DMF (5 ml), and 27 mg of sodium hydride was added thereto , followed by stirring at 70 ° C to 80 ° C for 20 minutes. Subsequently, 0.188 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole was added to the reaction solution while cooling by ice, followed by stirring at 70 ° C at 80 ° C for 20 minutes. Subsequently, the reaction solution was cooled to room temperature. Water was added to the reaction solution, and the repeat extraction was carried out with ethyl acetate. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then dried over sodium sulfate. The sodium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (from hexane: ethyl acetate = 1: 3 to ethyl acetate). The resulting product was recrystallized from a mixed solvent consisting of dichloromethane and ethyl acetate to obtain 88 mg (26.7%) of light yellow powder, (R) -2-methyl-6-nitro-2- (4 - (4- (4-trifluoromethylbenzyloxy) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 217.4 ° C-219.7 ° C Example 1469 (R) -2-methyl-6-nitro-2- (4- (4- (4-trifluoromethoxybenzyl) piperidin-1-yl) phenoxymethyl) -2, 3 -dihydroimidazo [2, 1-b] oxazole 8.41 g of 4- (4- (4-trifluoromethoxybenzyl) piperidin-1-yl) phenol was dissolved in DMF (84 ml), and 1.05 g of sodium hydride was added thereto , followed by stirring at 70 ° C to 80 ° C for 20 minutes. Subsequently, 7.29 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole was added to the reaction solution while cooling by ice, followed by stirring at 70 ° C at 80 ° C for 20 minutes. Subsequently, the reaction solution was cooled to room temperature. Water was added to the reaction solution, and the repeat extraction was carried out with ethyl acetate. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then dried over sodium sulfate. The sodium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate = 9: 1). The resulting product was recrystallized from a mixed solvent consisting of dichloromethane and ethyl acetate to obtain 4.65 g (36.5%) of light yellow powders, (R) -2-methyl-6-nitro-2- (4 - (4- (4-trifluoromethoxybenzyl) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. A-NMR (CDC13) dppm 1.23-1.52 (2H, m), 1.52-1.66 (3H, m), 1.66-1.89 (3H,), 2.43-2.70 (4H, m), 3.50 (2H, d, J = 12.1 Hz), 3.91-4.09 (2H,), 4.16 (HH, d, J = 10.1 Hz), 4.48 (HH, d, J = 10.2 Hz), 6.66-6.81 (2H, m), 6.81-6.95 (2H) , m), 7.05-7.23 (4H, m), 7.54 (1H, s) Melting point: 210.9 ° C-212.4 ° C (a) D = -9.0 deg. (c = 1.0, CHC13) Example 1470 (R) -2- (4- (4- (4-chlorobenzyl) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2, 3-dihydroimidazo [2, 1-b] oxazole 1.036 g of 4- (4- (4-chlorobenzyl) piperidin-1-yl) phenol was dissolved in DMF (5 ml), and 151 mg of sodium hydride was added to it, followed by stirring at 70 ° C to 80 ° C for 20 minutes. Subsequently, 1.04 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole was added to the reaction solution while cooling by ice, followed by stirring at 70 ° C at 80 ° C for 20 minutes. Subsequently, the reaction solution was cooled to room temperature. Water was added to the reaction solution, and the repeat extraction was carried out with ethyl acetate. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then dried over sodium sulfate. The sodium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (from hexane: ethyl acetate = 1: 3 to ethyl acetate). The resulting product was recrystallized from a mixed solvent consisting of dichloromethane and ethyl acetate to obtain 0.286 g (17.3%) of light yellow powder crystals, (R) -2- (4- (4- (4 -chlorobenzyl) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 207.1 ° C-211.2 ° C Example 1471 (R) -2-methyl-6-nitro-2- (4- (4- (4-trifluoromethoxycinnamyloxy) piperidin-1-yl) phenoxymethyl) -2, 3 -dihydroimidazo [2, 1-b] oxazole 2.21 g of 4- (4- (4-trifluoromethoxycinnamyloxy) piperidin-1-yl) phenol was dissolved in DMF (22 ml), and 0.247 g of sodium hydride was added thereto , followed by stirring at 70 ° C to 80 ° C for 20 minutes. Subsequently, 1.71 g of (R) -2-chloro-1- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole was added to the reaction solution while cooling by ice, followed by stirring at 70 ° C at 80 ° C for 20 minutes. Subsequently, the reaction solution was cooled to room temperature. Water was added to the reaction solution, and the repeat extraction was carried out with ethyl acetate. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then dried over anhydrous magnesium sulfate. The magnesium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate - 9: 1). The resulting product was recrystallized from a mixed solvent consisting of dichloromethane and ethyl acetate to obtain 0.70 g (21.7%) of light yellow powder crystals, (R) -2-methyl-6-nitro-2- (4- (4- (-trifluoromethoxycinnamyloxy) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 213.7 ° C-217.4 ° C Example 1472 (R) -6-nitro-2- (4- (4- (4-trifluoromethoxybenzyloxy) piperidin-1-yl) phenoxymethyl) -2, 3-dihydroimidazo [2 , 1-b] oxazole 4.60 g of 4- (4- (4-trifluoromethoxybenzyloxy) piperidin-1-yl) phenol was dissolved in DMF (46 ml), and 0.55 g of sodium hydride was added thereto, followed by stirring at 70 ° C to 80 ° C for 20 minutes. Subsequently, 3.57 g of (R) -2-chloro-l-oxiranylmethyl-4-nitro-lH-imidazole was added to the reaction solution while cooled by ice, followed by stirring at 70 ° C to 80 ° C for 20 minutes. minutes Subsequently, the reaction solution was cooled to room temperature. Water was added to the reaction solution, and the repeat extraction was carried out with ethyl acetate. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then dried over sodium sulfate. The sodium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate from 9: 1 to 6: 4).

The resulting product was recrystallized from a mixed solvent consisting of dichloromethane and ethyl acetate to obtain 0.99 g (14.8%) of light yellow powder crystals, (R) -6-nitro-2- (4- ( 4- (4-trifluoromethoxybenzyloxy) iperidin-1-yl) phenoxymethyl) -2, 3-dihydroimidazo [2, 1-b] oxazole. Melting point: 188.3A-189.4 ° C Example 1473 (R) -2-methyl-6-nitro-2- (4- (4- (2- (4-trifluoromethoxyphenyl) ethyl) piperidin-1-yl) phenoxymethyl) -2, 3-dihydroimidazo [2, 1-b] oxazole 1.01 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole and 1.36 g of 4- (4- (2- (4-trifluoromethoxyphenyl) ethyl) piperidin-1-yl) phenol were dissolved in DMF (14 ml), and 0.18 g of sodium hydride was added thereto, followed by stirring at 50 ° C for 1 hour. hour. Subsequently, the reaction solution was cooled to room temperature. Water was added to the reaction solution, and the repeat extraction was carried out with ethyl acetate. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then dried over sodium sulfate. The sodium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate from 9: 1 to 8: 2). The resulting product was recrystallized from a mixed solvent consisting of dichloromethane, ethyl acetate, and diisopropyl ether to obtain 0.70 g (34.4%) of light yellow powder crystals, (R) -2-methyl-6- nitro-2- (4- (4- (2- (4-trifluoromethoxyphenyl) ethyl) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 239.4 ° C-241.3 ° C Example 1474 (R) -2-methyl-6-nitro-2- (6- (4- (4-trifluoromethoxyphenoxy) piperidin-1-yl) pyridin-3-yloxymethyl) -2, 3-dihydroimidazo [2, 1-b] oxazole 0.51 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole and 0.67 g of 3- hydroxy-6- (4- (4-trifluoromethoxyphenoxy) piperidin-1-yl) pyridine were dissolved in DMF (6.7 ml), and 91 mg of sodium hydride was added thereto, followed by stirring at 50 ° C for 1 hour . Subsequently, the reaction solution was cooled to room temperature. Water was added to the reaction solution, and the repeat extraction was carried out with ethyl acetate. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then dried over anhydrous magnesium sulfate. The magnesium sulfate was filtered, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate from 9: 1 to 8: 2). The resulting product was recrystallized from a mixed solvent consisting of dichloromethane, ethyl acetate, and diisopropyl ether to obtain 296 mg (29.1%) of light yellow colored powder crystals, (R) -2-methyl-6- nitro-2- (6- (4- (4-trifluoromethoxyphenoxy) piperidin-1-yl) pyridin-3-yloxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 185.9 ° C-186.7 ° C Example 1475 (R) -6-Nitro-2- (4- (4- (4-trifluoromethoxybenzyl) piperidin-1-yl) phenoxymethyl) -2, 3-dihydroimidazo [2 , 1-b] oxazole 0.72 g of (R) -2-chloro-l-oxiranylmethyl-4-nitro-lH-imidazole and 1.00 g of 4- (4- (4-trifluoromethoxybenzyl) piperidin-1-yl) phenol dissolved in DMF (10 ml), and 0.14 g of sodium hydride was added thereto, followed by stirring at 50 ° C for 1 hour. Subsequently, the reaction solution was cooled to room temperature. Water was added to the reaction solution, and the repeat extraction was carried out with ethyl acetate. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then dried over anhydrous magnesium sulfate. The magnesium sulfate was filtered, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate from 9: 1 to 7: 3). The resulting product was recrystallized from a mixed solvent consisting of dichloromethane, ethyl acetate, and diisopropyl ether to obtain 0.20 g (13.7%) of light yellow powder crystals, (R) -6-nitro-2- (4- (4- (4-trifluoromethoxybenzyl) piperidin-1- il) phenoxymethyl) -2, 3-dihydroimidazo [2, 1-b] oxazole. Melting point: 160.5 ° C-164.0 ° C Example 1476 (R) -2-methyl-6-nitro-2- (4- (4- (4-trifluoromethoxyphenyl) -1,4-diazepan-1-yl) phenoxymethyl ) -2, 3-dihydroimidazo [2, 1-b] oxazole 2.21 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole and 2.86 g of 4 - (4- (4-trifluoromethoxy-phenyl) -1,4-diazepane-1-yl) phenol were dissolved in DMF (29 ml), and 0.39 g of sodium hydride was added thereto, followed by stirring at 50 ° C. 1 hour. Subsequently, the reaction solution was cooled to room temperature. Water was added to the reaction solution, and the repeat extraction was carried out with dichloromethane. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then concentrated. The residue was purified by silica gel column chromatography (from hexane: ethyl acetate = 1: 3 to ethyl acetate). The resulting product was then recrystallized from isopropyl alcohol to obtain 720 mg (16.6%) of red powders, (R) -2-methyl-6-nitro-2- (4- (4- (4-trifluoromethoxyphenyl) - 1,4-diazepan-1-yl) phenoxymethyl) -2,3-dihydroxy idazo [2, 1-b] oxazole. Melting point: 134.0 ° C-137.9 ° C Example 1477 (R) -2-methyl-2- (4- (4- (N-methyl-N- (2-fluoro-4-trifluoromethylbenzyl) amino) piperidin-Ail Phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole 0.80 g of (R) -2-methyl-2- (4- (4- (N-methyl-N-tert-butoxycarbonyl) ino) piperidin-1-yl) phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole was dissolved in 2 ml of trifluoroacetic acid and 2 ml of dichloromethane, followed by stirring at room temperature for 15 minutes. hours. Subsequently, the reaction solution was concentrated under reduced pressure, and then 2 ml of dichloromethane and 2 ml of triethylamine were added thereto. The mixture was stirred at room temperature for 5 minutes, and this was then concentrated under reduced pressure. The residue was dissolved in 8 ml of dichloroethane, and then, 0.63 g of 2-fluoro-4-trifluoromethylbenzaldehyde and 0.70 g of sodium triacetoxyborohydride were added thereto while being cooled by ice. The mixture was warmed to room temperature, and the mixture was then stirred for 24 hours. Subsequently, an aqueous solution of potassium carbonate and dichloromethane were added to the reaction solution. The mixture was stirred, and then extracted with dichloromethane. The organic layer was dried over magnesium sulfate, and then filtered. The obtained filtrate was concentrated under reduced pressure. The residue was purified by column chromatography on silica gel (dichloromethane: methanol = 9: 1). The resulting product was then crystallized from ethyl acetate to obtain 0.48 g (yield: 51.8%) of light yellow powders, (R) -2-methyl-2- (4- (4- (N-methyl- N- (2-fluoro-4-trifluoromethylbenzyl) amino) piperidin-1-yl) phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 197.5 ° C-199.2 ° C. Example 1478 (R) -2-methyl-2- (4- (4- (N-methyl-N- (2-trifluoromethylbenzyl) amino) iperidin-1-yl) phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole 0.80 g of (R) -2-methyl-2- (4- (4- (N-methyl-N-tert-butoxycarbonylamino) piperidin-1-yl) phenoxymethyl) -6-nitro -2,3-dihydroimidazo [2, 1-b] oxazole was dissolved in 2 ml of trifluoroacetic acid and 2 ml of dichloromethane, followed by stirring at room temperature for 15 hours. Subsequently, the reaction solution was concentrated under reduced pressure, and then, 2 ml of dichloromethane and 2 ml of triethylamine were added thereto. The mixture was stirred at room temperature for 5 minutes, and this was then concentrated under reduced pressure. The residue was dissolved in 8 ml of dichloroethane, and then, 0.57 g of 2-trifluoromethylbenzaldehyde and 0.70 g of sodium triacetoxyborohydride were added thereto while being cooled by ice. The mixture was heated to room temperature, and the mixture was then stirred for 24 hours. Subsequently, an aqueous solution of potassium carbonate and dichloromethane were added to the reaction solution. The mixture was stirred, and then extracted with dichloromethane. The organic layer was dried over magnesium sulfate, and then filtered. The obtained filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: methanol = 9: 1). The resulting product was then crystallized from ethyl acetate to obtain 0.47 g (yield: 52.4%) of light yellow powders, (R) -2-methyl-2- (4- (4- (N-methyl- N- (2-trifluoromethylbenzyl) amino) -piperidin-1-yl) phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 18.6 ° C-190.2 ° C Example 1479 (R) -2-methyl-2- (4- (4- (N-methyl-N- (3,5-bistrifluoromethylbenzyl) amino) piperidin-1 -yl) phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole 0.80 g of (R) -2-methyl-2- (4- (4- (N-ethyl-N-tert -butoxycarbonylamino) piperidin-1-yl) phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole was dissolved in 2 ml of trifluoroacetic acid and 2 ml of dichloromethane, followed by stirring at room temperature during 15 hours. Subsequently, the reaction solution was concentrated under reduced pressure, and then, 2 ml of dichloromethane and 2 ml of triethylamine were added thereto. The mixture was stirred at room temperature for 5 minutes, and this was then concentrated under reduced pressure. The residue was dissolved in 8 ml of dichloroethane, and then, 0.79 g of 3,5-bistrifluoromethylbenzaldehyde and 0.70 g of sodium triacetoxyborohydride were added thereto while being cooled by ice. The mixture was warmed to room temperature, and the mixture was then stirred for 19 hours. Subsequently, an aqueous solution of potassium carbonate and dichloromethane were added to the reaction solution. The mixture was stirred, and then extracted with dichloromethane. The organic layer was dried over magnesium sulfate, and then filtered. The obtained filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: methanol = 9: 1). The resulting product was then crystallized from ethyl acetate to obtain 0.55 g (yield: 54.9%) of light yellow powders, (R) -2-methyl-2- (4- (4- (N-methyl- N- (3,5-bistrifluoromethylbenzyl) amino) piperidin-1-yl) phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 193.8 ° C-195.3 ° C.

Example 1480 (R) -2-methyl-6-nitro-2- (4- (4- (3-trifluoromethoxybenzyl) piperidin-1-yl) phenoxymethyl) -2, 3-dihydroimidazo [2, 1-b] oxazole 1.21 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole and 1. 56 g of 4- (4- (3-trifluoromethoxybenzyl) piperidine- 1-yl) phenol were dissolved in DMF (16 ml), and 0.21 g of sodium hydride was then added thereto, followed by stirring at 50 ° C for 1 hour. Subsequently, the reaction solution was cooled to room temperature. Water was added to the reaction solution, and the mixture was then extracted repeatedly with dichloromethane. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then dried over anhydrous sodium sulfate. The sodium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate from 9: 1 to 8: 2). The resulting product was recrystallized from a mixed solvent consisting of dichloromethane, ethyl acetate, and diisopropyl ether to obtain 0. 80 g (33.8%) of light yellow powder crystals, (R) -2-methyl-6-nitro-2- (4- (4- (3-trifluoromethoxybenzyl) piperidin-1-yl) phenoxymethyl ) -2, 3-dihydroimidazo [2, 1-b] oxazole. Melting point: 187. 4 ° C-189. 8 ° C Example 1481 (R) -2-methyl-2- (4- (4- (N-methyl-N- (5-chlorobenzofuran-2-ylmethyl) amino) piperidin-1-yl) phenoxymethyl) -6- nitro-2, 3-dihydroimidazo [2, 1-b] oxazole 0.80 g of (R) -2-methyl-2- (4- (4- (N-methyl-N-tert-butoxycarbonylamino) piperidin-1-yl Phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole was dissolved in 2 ml of trifluoroacetic acid and 2 ml of dichloromethane, followed by stirring at room temperature for 15 hours. Subsequently, the reaction solution was concentrated under reduced pressure, and then, 2 ml of dichloromethane and 2 ml of triethylamine were added thereto. The mixture was stirred at room temperature for 5 minutes, and this was then concentrated under reduced pressure. The residue was dissolved in 8 ml of dichloroethane, and then, 0.59 g of 5-chlorobenzofuran-2-carbaldehyde and 0.70 g of sodium triacetoxyborohydride were added thereto while being cooled by ice. The mixture was warmed to room temperature, and the mixture was then stirred for 22 hours. Subsequently, an aqueous solution of potassium carbonate and dichloromethane were added to the reaction solution. The mixture was stirred, and then extracted with dichloromethane. The organic layer was dried over magnesium sulfate, and then filtered. The obtained filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: methanol = 9: 1). The resulting product was then crystallized from acetone to obtain 0.65 g (yield: 66.5%) of yellow powders, (R) -2-methyl-2- (4- (4- (N-methyl-N- ( 5-chlorobenzofuran-2-ylmethyl) amino) piperidin-1-yl) phenoxymethyl) -6-nitro-2, 3-dihydroimidazo [2, 1-b] oxazole. Melting point: 207. 4A-210. 0 ° C Example 1482 (R) -2-methyl-6-nitro-2- (6- (4- (4-trifluoromethoxybenzyl) iperidin-1-yl) pyridin-3-yloxymethyl) -2,3-dihydroimidazo [2 , 1-b] oxazole 2.63 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole and 3.41 g of 3-hydroxy-6- (4- ( 4-trifluoromethoxybenzyl) piperidin-1-yl) pyridine were dissolved in DMF (6.7 ml), and 0.46 g of sodium hydride was then added thereto, followed by stirring at 50 ° C for 1.5 hour. Subsequently, the reaction solution was cooled to room temperature. Water was added to the reaction solution, and the mixture was then extracted repeatedly with dichloromethane. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then dried over anhydrous magnesium sulfate. The magnesium sulfate was filtered, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate from 9: 1 to 6: 4). The resulting product was recrystallized from a mixed solvent consisting of ethyl acetate and diisopropyl ether to obtain 1.46 g (28.3%) of light yellow powder crystals., (R) -2-methyl-6-nitro-2- (6- (4- (4-trifluoromethoxybenzyl) piperidin-1-yl) pyridin-3-yloxymethyl) -2, 3-dihydroimidazo [2, 1-b ] oxazole Melting point: 200. 1 ° C-202.9 ° C Example 1483 (R) -6-nitro-2- (4- (4- (2- (4-trifluoromethoxyphenyl) ethyl) piperidin-1-yl) phenoxymethyl) - 2,3-dihydroimidazo [2, 1-b] oxazole 0.75 g of (R) -2-chloro-l-oxiranylmethyl-4-nitro-lH-imidazole and 1.07 g of 4- (4- (2- (4- trifluoromethoxyphenyl) ethyl) piperidin-1-yl) phenol were dissolved in DMF (11 ml), and 0.14 g of sodium hydride was then added thereto, followed by stirring at 50 ° C for 1 hour. Subsequently, the reaction solution was cooled to room temperature. Water was added to the reaction solution, and the mixture was then extracted repeatedly with dichloromethane. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then dried over magnesium sulfate. The magnesium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate from 9: 1 to 6: 4). The resulting product was recrystallized from a mixed solvent consisting of dichloromethane and diisopropyl ether to obtain 0.31 g (19.8%) of light yellow powder crystals, (R) -6-nitro-2- (4- (4 - (2- (4-trifluoromethoxyphenyl) ethyl) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 208.9 ° C-211.7 ° C Example 1484 (R) -2-methyl-2- (4- (4- (N-methyl-N- (4-trifluoromethoxycinnamyl) amino) piperidin-1-yl) phenoxymethyl ) -6-nitro-2, 3-dihydroimidazo [2, 1-b] oxazole 2.76 g of (R) -2-methyl-2- (4- (4- (N-methyl-N-tert-butoxy carbonyl amino ) piperidin-1-yl) phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole was dissolved in 5 ml of trifluoroacetic acid and 10 ml of dichloromethane, followed by stirring at room temperature for 0. 5 hours . Subsequently, the reaction solution was concentrated under reduced pressure, and then, 10 ml of dichloromethane and 10 ml of N, N-dimethylethylamine were added thereto. The mixture was stirred at room temperature for 10 minutes, and this was then concentrated under reduced pressure. The residue was dissolved in 30 ml of dichloroethane, and 1.43 g of 4-trif luoromethoxycinnamaldehyde and 1.78 g of sodium triacetoxyborohydride were then added thereto while being cooled by ice. The mixture was warmed to room temperature, followed by stirring overnight. Subsequently, an aqueous solution of potassium carbonate and dichloromethane were added to the reaction solution. The mixture was stirred, and then extracted with dichloromethane. The organic layer was dried over magnesium sulfate, and then filtered. The obtained filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: acetone from 5: 1 to 1: 1). The resulting product was then recrystallized from an aqueous acetone to obtain 1.976 g (yield: 58.9%) of light yellow powders, (R) -2-methyl-2- (4- (4- (N-methyl- N- (4-trifluoromethoxycinnamyl) amino) piperidin-1-yl) phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 213.0 ° C-214.9 ° C Example 1485 (R) -2- (4- (4- (3, 4-dichlorocinnamyl) piperazin-1-yl) phenoxymethyl) -2-methyl-6-nitro -2, 3-dihydroimidazo [2, 1-b] oxazole 2.76 g of (R) -2-methyl-2- (4- (4-tert-butoxycarbonyl piperazin-1-yl) phenoxymethyl) -6-nitro-2 , 3-dihydroimidazo [2, 1-b] oxazole was dissolved in 5 ml of trifluoroacetic acid and 10 ml of dichloromethane, followed by stirring at room temperature for 0.5 hour. Subsequently, the reaction solution was concentrated under reduced pressure, and then, 10 ml of dichloromethane and 10 ml of N, N-dimethylethylamine were added thereto. The mixture was stirred at room temperature for 5 minutes, and this was then concentrated under reduced pressure. The residue was dissolved in 30 ml of dichloroethane, and 1.33 g of 3,4-dichlorocinamyl aldehyde and 1.78 g of sodium triacetoxyborohydride were then added thereto. The mixture was stirred at room temperature overnight. Later, an aqueous solution of potassium carbonate and dichloromethane were added to the reaction solution. The mixture was stirred, and then extracted with dichloromethane. The organic layer was dried over magnesium sulfate, and then filtered. The obtained filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: acetone from 5: 1 to 1: 1). The resulting product was then crystallized from a mixed solvent consisting of dichloromethane and ethyl acetate to obtain 2,243 g (yield: 68.7%) of light yellow powders, (R) -2- (4- (4- ( 3, 4-dichlorocinnamyl) piperazin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 204.7 ° C-206.4 ° C Example 1486 (R) -2-methyl-2- (4- (N-methyl-N- (1- (4-trifluoromethoxyphenyl) piperidin-4-ylmethyl) amino) phenoxymethyl ) -6-nitro-2, 3-dihydroimidazo [2, 1-b] oxazole 0.408 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-i idazole and 0.57 g of 4- (N-methyl-N- (1- (4-trifluoromethoxyphenyl) piperidin-4-ylmethyl) amino) phenol were dissolved in 6 ml of DMF, and 72 mg of sodium hydride was then added thereto. , followed by stirring at 50 ° C at 60 ° C for 2 hours. Subsequently, the reaction solution was cooled to room temperature. Water was added to the reaction solution, and the mixture was then extracted repeatedly with ethyl acetate. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then dried over magnesium sulfate. The magnesium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (from hexane: ethyl acetate = 1: 3 to dichloromethane: ethyl acetate = 1: 1). The resulting product was recrystallized from an aqueous acetone to obtain 0.130 g (yield: 15.4%) of orange powder crystals, (R) -2-methyl-2- (4- (N-methyl-N- ( 1- (4-trifluoromethoxyphenyl) piperidin-4-ylmethyl) amino) phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 172.5 ° C-175.2 ° C Example 1487 (R) -2-methyl-2- (4- (N-methyl-N- (1- (4-trifluoromethoxyphenyl) piperidin-4-ylmethyl) amino) phenoxymethyl ) -6-nitro-2, 3-dihydroimidazo [2, 1-b] oxazole 0.131 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-i idazole and 0.177 g of 4- (N-methyl-N- (1- (4-trifluoromethoxyphenyl) piperidin-4-yl) amino) phenol were dissolved in 4 ml of DMF, and 23 mg of sodium hydride was then added thereto. , followed by stirring at 50 ° C at 60 ° C for 2 hours. Subsequently, the reaction solution was cooled to room temperature. Water was added to the reaction solution, and the mixture was then extracted repeatedly with ethyl acetate. The combined organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and then dried over magnesium sulfate. The magnesium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (from hexane: ethyl acetate = 1: 3 to dichloromethane: ethyl acetate = 1: 1). The resulting product was recrystallized from an aqueous acetone to obtain 93 mg (yield: 35%) of light yellow powder crystals, (R) -2-methyl-2- (4- (N-methyl-N- (1- (4-trifluoromethoxyphenyl) piperidin-4-yl) amino) phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 137.9 ° C-139.2 ° C Example 1488 (R) -2-methyl-6-nitro-2- (4- (1- (2- (4-trifluoromethylphenyl) thiazol-4-ylmethyl) piperidin-4 -yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole 0.300 g of (R) -2-methyl-6-nitro-2- (4- (l-tert-butoxycarbonylpiperidin-4-yl) phenoxymethyl) -2,3-dihydroimidazo [2,1-b] oxazole was added to 1 ml of trifluoroacetic acid and 1 ml of dichloromethane, followed by stirring at room temperature for 1 hour. Subsequently, the reaction solution was concentrated under reduced pressure, the residue was then dissolved in 1 ml of dichloromethane, and 1 ml of triethylamine was then added thereto. The mixture was stirred at room temperature for 5 minutes, and this was then concentrated under reduced pressure. The residue was dissolved in 5 ml of methanol, and then, 0.219 g of 2- (4-trifluoromethylphenyl) thiazole-4-carbaldehyde, 82 mg of sodium cyanotriborohydrate, and 0.5 ml of acetic acid were added thereto while cooled by ice. The obtained mixture was stirred at room temperature for 3 days. Subsequently, a saturated aqueous solution of sodium bicarbonate was added thereto. The mixture was stirred, extracted with ethyl acetate, and then washed with a saturated aqueous solution of sodium chloride. The organic layer was dried over magnesium sulfate, and then concentrated under reduced pressure. The residue was purified by silica gel column chromatography (from dichloromethane: acetone = 3: 1 to dichloromethane: methanol = 20: 1). The resulting product was then recrystallized from an aqueous acetone to obtain 65 mg (yield: 16.6%) of white powders, (R) -2-methyl-6-nitro-2- (4- (1- (2 - (4-trifluoromethylphenyl) thiazol-4-ylmethyl) piperidin-4-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 194.6 ° C-196.4 ° C Example 1489 (R) -2-methyl-6-nitro-2- (4- (1- (4-trifluoromethylcinnamyl) piperidin-4-yl) phenoxymethyl) -2, 3 - dihydroimidazo [2, 1-b] oxazole 0.300 g of (R) -2-methyl-6-nitro-2- (4- (1-tert-butoxycarbonylpiperidin-4-yl) phenoxymethyl) -2, 3-dihydroimidazo [ 2, 1-b] oxazole was added to 1 ml of trifluoroacetic acid and 1 ml of dichloromethane, followed by stirring at room temperature for 1 hour. Subsequently, the reaction solution was concentrated under reduced pressure, the residue was then dissolved in 1 ml of dichloromethane, and 1 ml of triethylamine was then added thereto. The mixture was stirred at room temperature for 5 minutes, and this was then concentrated under reduced pressure. The residue was dissolved in 5 ml of methanol, and then, 0.170 g of 4-trifluoromethylcinnamaldehyde, 82 mg of sodium cyanotriborohydrate, and 0.5 ml of acetic acid were added thereto while being cooled by ice. Subsequently, the obtained mixture was stirred at room temperature for 3 days. A saturated aqueous solution of sodium bicarbonate was added thereto. The mixture was stirred, extracted with ethyl acetate, and then washed with a saturated aqueous solution of sodium chloride. The organic layer was dried over magnesium sulfate, and then concentrated under reduced pressure. The residue was purified by silica gel column chromatography (from dichloromethane: acetone = 3: 1 to dichloromethane: methanol = 20: 1). The resulting product was then recrystallized from an aqueous acetone to obtain 66 mg (yield: 18.6%) of white powders, (R) -2-methyl-6-nitro-2- (4- (1- (4 -trifluoromethylcinyl) piperidin-4-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 185.9 ° C-187.1 ° C. Example 1490 (R) -2-methyl-6-nitro-2- (4- (4- (2- (4-trifluoromethoxyphenoxy) ethyl) piperazin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1 -b] oxazole 0.300 g of (R) -2-methyl-6-nitro-2- (4- (4-tert-butoxycarbonylpiperazin-1-yl) phenoxymethyl) -2, 3-dihydroimidazo [2, 1-b] oxazole was added to 3 ml of trifluoroacetic acid and 3 ml of dichloromethane, followed by stirring at room temperature for 2 hours. Subsequently, the reaction solution was concentrated under reduced pressure, the residue was then dissolved in 3 ml of dichloromethane, and 3 ml of triethylamine was then added thereto. The mixture was stirred at room temperature for 10 minutes, and this was then concentrated under reduced pressure. The residue was dissolved in 5 ml of methanol, and then, 0.170 g of 4-trifluoromethoxyphenoxyacetaldehyde, 82 mg of sodium cyanotriborohydrate, and 0.1 ml of acetic acid were added thereto while being cooled by ice.

Subsequently, the obtained mixture was stirred at room temperature overnight. A saturated aqueous solution of sodium bicarbonate was added thereto. The mixture was stirred, extracted with ethyl acetate, and then washed with a saturated aqueous solution of sodium chloride. The organic layer was dried over magnesium sulfate, and then concentrated under reduced pressure. The residue was purified by silica gel column chromatography (from dichloromethane: acetone = 3: 1 to dichloromethane: methanol = 20: 1). The resulting product was then recrystallized from an aqueous acetone to obtain 157 mg (yield: 42.7%) of white powders, (R) -2-methyl-6-nitro-2- (4- (4- (2 - (4-trifluoromethoxyphenoxy) ethyl) piperazinyl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 194.8 ° C-195.6 ° C Example 1491 (R) -2-methyl-6-nitro-2- (4- (4- (4-trifluoromethyl-acyl) -piperazin-1-yl) phenoxymethyl) -2, 3 -dihydroimidazo [2, 1-b] oxazole 0.300 g of (R) -2-methyl-6-nitro-2- (4- (4-tert-butoxycarbonylpiperazin-1-yl) phenoxymethyl) -2, 3-dihydroimidazo [ 2, 1-b] oxazole was added to 3 ml of trifluoroacetic acid and 3 ml of dichloromethane, followed by stirring at room temperature for 1 hour. Subsequently, the reaction solution was concentrated under reduced pressure, the residue was then dissolved in 3 ml of dichloromethane, and 3 ml of triethylamine was then added thereto. The mixture was stirred at room temperature for 5 minutes, and this was then concentrated under reduced pressure. The residue was dissolved in 5 ml of methanol, and then, 0.170 g of 4-trifluoromethyl-amylaldehyde, 82 mg of sodium cyanotriborohydrate, and 0.1 ml of acetic acid were added thereto while being cooled by ice. The obtained mixture was stirred at room temperature for 3 days. Subsequently, a saturated aqueous solution of sodium bicarbonate was added thereto. The mixture was stirred, extracted with ethyl acetate, and then washed with a saturated aqueous solution of sodium chloride. The organic layer was dried over magnesium sulfate, and then concentrated under reduced pressure. The residue was purified by silica gel column chromatography (from dichloromethane: acetone = 3: 1 to dichloromethane: methanol = 20: 1). The resulting product was then recrystallized from an aqueous acetone to obtain 66 mg (yield: 18.6%) of light yellow powders, (R) -2-methyl-6-nitro-2- (4- (4- ( 4-trifluoromethylcinyl) piperazin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 199.7 ° C-202.0 ° C Example 1492 (R) -2-methyl-6-nitro-2- (4- (4- (2- (4-trifluoromethylphenyl) thiazol-4-ylmethyl) piperazine-1 -yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole 0.300 g of (R) -2-methyl-6-nitro-2- (4- (4-tert-butoxycarbonylpiperazin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole was added to 3 ml of trifluoroacetic acid and 3 ml of dichloromethane, followed by stirring at room temperature for 2 hours. Subsequently, the reaction solution was concentrated under reduced pressure. The residue was dissolved in 3 ml of dichloromethane, and 3 ml of triethylamine was then added thereto. The mixture was stirred at room temperature for 10 minutes, and then concentrated under reduced pressure. The residue was dissolved in 5 ml of methanol, and then, 0.218 g of 2- (4-trifluoromethylphenyl) thiazole-4-carbaldehyde, 82 mg of sodium cyanotriborohydrate, and 0.5 ml of acetic acid were added thereto while cooling by ice. The mixture was stirred at room temperature overnight. Subsequently, a saturated aqueous solution of sodium bicarbonate was added thereto. The mixture was stirred, then extracted with ethyl acetate, and then washed with a saturated aqueous solution of sodium chloride. The organic layer was dried over magnesium sulfate, and then concentrated under reduced pressure. The residue was purified by silica gel column chromatography (from dichloromethane: acetone = 3: 1 to dichloromethane: methanol = 20: 1). The resulting product was then crystallized from an aqueous acetone to obtain 0.167 g (yield: 42.6%) of white powders., (R) -2-methyl-6-nitro-2- (4- (4- (2- (4-trifluoromethyl) enyl) thiazol-4-ylmethyl) piperazin-1-yl) phenoxymethyl) -2, 3- dihydroimidazo [2, 1-b] oxazole. Melting point: 210. OA-212. 1 ° C Example 1493 (R) -2- (4- (4- (N- (4-chlorophenyl) -N-methylamino) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2, 3-dihydroimidazo [2, 1-b] oxazole 776 mg of 4- (4- (N- (4-chlorophenyl) -N-methylamino) piperidin-1-yl) phenol was dissolved in 10 ml of DMF, and 108 mg of sodium hydride was then added thereto, followed by stirring at 70 ° C to 80 ° C for 10 minutes. Subsequently, the reaction solution was cooled by ice, and 746 mg of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole was then added thereto, followed by stirring at 70 ° C to 80 ° C for 20 minutes. Subsequently, the reaction solution was cooled to room temperature. Ice water was added to the reaction solution, the mixture was then stirred, and the insoluble precipitate was then removed by filtration. The filtrate was dissolved in dichloromethane, washed with a saturated aqueous solution of sodium chloride, and then dried over magnesium sulfate. The magnesium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate = 10: 1). The resulting product was then recrystallized from a mixed solvent consisting of dichloromethane and ethyl acetate to obtain 485 mg (yield: 39.8%) of white powder crystals, (R) -2- (4- (4- (N- (4-chlorophenyl) -N-methylamino) iperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 173.7 ° C-175.1 ° C Example 1494 (R) -2-methyl-6-nitro-2- (4- (4- (4-trifluoromethylphenoxymethyl) piperidin-1-yl) phenoxymethyl) -2, 3 -dihydroimidazo [2, 1-b] oxazole 574 mg of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-i idazole and 844 mg of 4- (4- (4-trifluoromethylphenoxymethyl) piperidin-1-yl) phenol were heated at 140 ° C, followed by stirring for 4 hours. Subsequently, the mixture was cooled to room temperature, and the mixture was then purified by silica gel column chromatography (hexane: ethyl acetate = 1: 3). After the end of the concentration, the residue was dissolved in 10 ml of DMF. 174 mg of sodium tert-butoxide was added thereto while cooled by ice, and the mixture was then stirred at room temperature for 2 hours. Subsequently, the solvent was removed under reduced pressure, and then, 100 ml of acetone and 10 ml of silica gel were added to the residue, followed by concentration. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate from 10: 1 to 1: 1). The resulting product was then recrystallized from a mixed solvent consisting of dichloromethane and ethyl acetate to obtain 1.15 g (yield: 38%) of white powders, (R) -2-methyl-6-nitro-2- (4- (4- (4-trifluoromethylphenoxymethyl) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 223.2 ° C-225.2 ° C (dec.) Example 1495 (R) -2-methyl-6-nitro-2- (4- (4- (4-trifluoromethylbenzyloxymethyl) piperidin-1-yl) phenoxymethyl) - 2, 3-dihydroimidazo [2, 1-b] oxazole 2.48 g of 4- (4- (4-trifluoromethylbenzyloxymethyl) piperidin-1-yl) phenol was dissolved in 30 ml of DMF, and 312 mg of sodium hydride was then added. added thereto, followed by stirring at 70 ° C to 80 ° C for 10 minutes. Subsequently, the reaction solution was cooled by ice, and 2.07 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-ylidazole was then added thereto, followed by stirring at 70 ° C to 80 ° C for 20 minutes. Subsequently, the reaction solution was cooled to room temperature. Ice water was added to the reaction solution, the mixture was then stirred, and the insoluble precipitate was then removed by filtration. The filtrate was dissolved in dichloromethane, washed with a saturated aqueous solution of sodium chloride, and then dried over magnesium sulfate. The magnesium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate = 10: 1). The resulting product was then recrystallized from ethyl acetate to obtain 1.66 g (yield: 44.7%) of white powder crystals, (R) -2-methyl-6-nitro-2- (4- (4- ( 4-trifluoromethylbenzyloxymethyl) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 172.3A-172.9 ° C Example 1496 (R) -2-methyl-6-nitro-2- (4- (4- (4-chloromethylphenoxymethyl) piperidin-1-yl) phenoxymethyl) -2, 3- dihydroimidazo [2, 1-b] oxazole 1.09 g of 4 ~ (4- (4-chloromethylphenoxymethyl) piperidin-1-yl) phenol was dissolved in 20 ml of DMF, and 158 mg of sodium hydride was then added thereto, followed by stirring at 70 ° C to 80 ° C for 20 minutes. Subsequently, the reaction solution was cooled by ice, and 1.04 g of (R) -2-chloro-l- (2-methyl-2-oxyranylmethyl) -4-nitro-lH-imidazole was then added thereto, followed by stirring at 60 ° C for 30 minutes. Subsequently, the reaction solution was cooled to room temperature. Ice water was added to the reaction solution, the mixture was then stirred, and the insoluble precipitate was then removed by filtration. The filtrate was dissolved in dichloromethane, washed with a saturated aqueous solution of sodium chloride, and then dried over magnesium sulfate. The magnesium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: methanol = 20: 1). The resulting product was then recrystallized from ethyl acetate to obtain 744 mg (yield: 43.5%) of light yellow powder crystals, (R) -2-methyl-6-nitro-2- (4- (4- (4-chloromethylphenoxymethyl) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 140.4 ° C-141.7 ° C Example 1497 (R) -6-Nitro-2- (4- (4- (4-trifluoromethylphenoxymethyl) piperidin-1-yl) phenoxymethyl) -2, 3-dihydroimidazo [2 , 1-b] oxazole 1.22 g of 4- (4- (4-trifluoromethylphenoxymethyl) piperidin-1-yl) phenol was dissolved in 15 ml of DMF, and 196 mg of sodium hydride was then added thereto, followed by stirring at 70 ° C to 80 ° C for 30 minutes. Subsequently, the reaction solution was cooled by ice, and 1.57 g of (R) -2-chloro-l-oxiranylmethyl-4-nitro-lH-imidazole was then added thereto, followed by stirring at 80 ° C for 20 minutes. . Subsequently, the reaction solution was cooled to room temperature. Ice water was added to the reaction solution, the mixture was then stirred, and the insoluble precipitate was then removed by filtration. The filtrate was dissolved in dichloromethane, washed with a saturated aqueous solution of sodium chloride, and then dried over magnesium sulfate. The magnesium sulfate was filtered, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: methanol = 20: 1). The resulting product was then recrystallized from ethyl acetate to obtain 505 mg (yield: 22.1%) of white powder crystals, (R) -6-nitro-2- (4- (4- (4-trifluoromethyl) enoxymethyl) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 175. 0 ° C-180 ° C Example 1498 (R) -2- (4'- (4- (4-chlorobenzyl) piperazin-1-yl) biphenyl-4-yloxymethyl) -2-methyl-6-nitro-2 , 3-dihydroimidazo [2, 1-b] oxazole 850 mg of (R) -2-methyl-2- (4'- (4-tert-butoxycarbonylpiperazin-1-yl) biphenyl-4-yloxymethyl) -6-nitro -2,3-dihydroimidazo [2, 1-b] oxazole was dissolved in 10 ml of trifluoroacetic acid and 5 ml of dichloromethane, followed by stirring at room temperature overnight. Subsequently, the reaction solution was concentrated under reduced pressure, and then, 6 ml of dichloromethane and 6 ml of triethylamine were added thereto. The mixture was stirred at room temperature for 5 minutes, and this was then concentrated under reduced pressure. The residue was dissolved in 10 ml of DMF, and then, 444.2 mg of 4-chlorobenzaldehyde and 672 mg of sodium triacetoxyborohydride were added thereto while being cooled by ice, followed by stirring at room temperature overnight. Subsequently, a solution of aqueous sodium bicarbonate and ethyl acetate were added to the reaction solution, the mixture was stirred, and the insoluble precipitate was removed by filtration. The filtrate was washed with water and ethyl acetate, and then dried to obtain 730 mg (yield: 51.8%) of light yellow powders, (R) -2- (4'- (4- (4-chlorobenzyl) piperazin-lyl) biphenyl-4-yloxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 247.8 ° C-248.5 ° C (decomposed) Example 1499 (R) -2-methyl-6-nitro-2- (4 '- (4- (4-trifluoromethyl-benzyl) piperazin-1-yl) biphenyl- 4-yloxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole 790 mg of (R) -2-methyl-2- (4 '- (4-tert-butoxycarbonylpiperazin-1-yl) bifenyl-4 -yloxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole was dissolved in 10 ml of trifluoroacetic acid and 5 ml of dichloromethane, followed by stirring at room temperature overnight. Subsequently, the reaction solution was concentrated under reduced pressure, and then, 6 ml of dichloromethane and 6 ml of triethylamine were added thereto. The mixture was stirred at room temperature for 5 minutes, and this was then concentrated under reduced pressure. The residue was dissolved in 15 ml of DMF, and then, 0.4 ml of 4-trifluoromethylbenzaldehyde and 625 mg of sodium triacetoxyborohydride were added thereto while cooling by ice, followed by stirring at room temperature overnight. Subsequently, water was added to the reaction solution, the mixture was stirred, and the insoluble precipitate was removed by filtration. The filtrate was washed with water and then dissolved in dichloromethane. The obtained solution was washed with a saturated aqueous solution of sodium chloride, and then dried over sodium sulfate. The sodium sulfate was filtered, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: methanol = 20: 1). The resulting product was then recrystallized from a mixed solvent consisting of dichloromethane and ethyl acetate to obtain 585 mg (yield: 60.5%) of light yellow powder, (R) -2-methyl-6-nitro-2 - (4'- (4- (4-trifluoromethylbenzyl) piperazin-1-yl) biphenyl-4-yloxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 247.7 ° C-248.4 ° C (decomposition) Example 1500 (R) -2-methyl-6-nitro-2- (4- (4- (2- (4-trifluoromethoxybenzyloxy) ethyl) piperidin-1- il) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole 959 mg of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole and 1.24 g of 4- (4- (2- (4-trifluoromethoxybenzyloxy) ethyl) piperidin-1-yl) phenol were dissolved in 20 ml of DMF, and 176 mg of sodium hydride was then added thereto, followed by stirring at 55 ° C. ° C for 1 hour. Subsequently, the temperature of the reaction solution was cooled to room temperature. Ice water was added to the reaction solution, the mixture was then stirred, and the insoluble precipitate was then removed by filtration. The filtrate was dissolved in dichloromethane, washed with a saturated aqueous solution of sodium chloride, and then dried over esium sulfate. The esium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate = 10: 1). The resulting product was then recrystallized from a mixed solvent consisting of dichloromethane and ethyl acetate to obtain 562 mg (yield: 28.8%) of white powder crystals, (R) -2-methyl-6-nitro- 2- (4- (4- (2- (4-trifluoromethoxybenzyloxy) ethyl) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole.

Melting point: 204. 8 ° C-206. 7 ° C Example 1501 (R) -2-methyl-6-nitro-2- (4- (4- (2- (4-trifluoromethylbenzyloxy) ethyl) piperidin-1-yl) phenoxymethyl) -2, 3-dihydroimidazo [2, 1-b] oxazole 741 mg of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole and 1.00 g of 4- (4- (2- (4-trifluoromethylbenzyloxy) ethyl) piperidin-1-yl) phenol were dissolved in 10 ml of DMF, and 136 mg of sodium hydride was then added thereto, followed by stirring at 55 ° C for 1 hour. Subsequently, the reaction solution was cooled to room temperature. Ice water was added to the reaction solution, the mixture was then stirred, and the insoluble precipitate was then removed by filtration. The filtrate was dissolved in dichloromethane, washed with a saturated aqueous solution of sodium chloride, and then dried over esium sulfate. The esium sulfate was filtered, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate = 10: 1). The resulting product was then recrystallized from a mixed solvent consisting of dichloromethane and ethyl acetate to obtain 548 mg (yield: 37.3%) of white powder crystals, (R) -2-methyl-6-nitro- 2- (4- (4- (2- (4-trifluoromethylbenzyloxy) ethyl) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole.

Melting point: 198 0 ° C-199. 2 ° C Example 1502 (R) -2- (4- (4- (2- (4-chlorobenzyloxy) ethyl) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole 900 mg of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole and 1.10 g of 4- (4- (2- (4-chlorobenzyloxy) ethyl) piperidin-1-yl) phenol were dissolved in 10 ml of DMF, and 165 mg of sodium hydride was then added thereto, followed by stirring at 55 ° C for 1 hour. Subsequently, the reaction solution was cooled to room temperature. Ice water was added to the reaction solution, the mixture was then stirred, and the insoluble precipitate was then removed by filtration. The filtrate was dissolved in dichloromethane, washed with a saturated aqueous solution of sodium chloride, and then dried over esium sulfate. The esium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate = 10: 1). The resulting product was then recrystallized from a mixed solvent consisting of dichloromethane and ethyl acetate to obtain 548 mg (yield: 37.3%) of white powder crystals, '(R) -2- (4- (4 - (2- (4-chlorobenzyloxy) ethyl) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 197.6 ° C-198.2 ° C Example 1503 (R) -2-methyl-6-nitro-2- (4- (4- (4- (4- (4-trifluoromethoxyphenoxy) piperidin-1-yl) benzyl) piperazin-lyl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole 350 mg of (R) -2-methyl-2- (4- (4-tert-butoxycarbonylpiperazin-1-yl) phenoxymethyl) ) -6-nitro-2, 3-dihydroimidazo [2, 1-b] oxazole was dissolved in 10 ml of trifluoroacetic acid, followed by stirring at room temperature for 5 hours. Subsequently, the reaction solution was concentrated under reduced pressure, and then, 2 ml of dichloromethane and 2 ml of triethylamine were added thereto. The mixture was stirred at room temperature for 5 minutes, and this was then concentrated under reduced pressure. The residue was dissolved in 10 ml of dichloroethane, and then, 278 mg of 4- (4- (4-trifluoromethoxyphenoxy) piperidin-1-yl) benzaldehyde and 242 mg of sodium triacetoxyborohydride were added thereto while cooled by ice, followed by stirring at room temperature overnight. Subsequently, a solution of aqueous sodium bicarbonate was added to the reaction solution, and then extracted with dichloromethane. The extract was washed with a saturated aqueous solution of sodium chloride, and then dried over magnesium sulfate.

The magnesium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: ethyl acetate = 10: 1). The resulting product was then recrystallized from a mixed solvent consisting of dichloromethane and diisopropyl ether to obtain 295 mg (yield: 55%) of light yellow powders, (R) -2-methyl-6-nitro-2- (4- (4- (4- (4- (4-trifluoromethoxyphenoxy) piperidin-1-yl) benzyl) piperazin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 198.2 ° C-201.4 ° C Example 1504 (R) -2- (4 '- (4- (3,4-dichlorobenzyl) piperazin-1-yl) biphenyl-4-yloxymethyl) -2-methyl- 6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole 350 mg of (R) -2-methyl-2- (4'- (4-tert-butoxycarbonylpiperazin-1-yl) biphenyl-4-yloxymethyl) ) -6-nitro-2, 3-dihydroimidazo [2, 1-b] oxazole was dissolved in 10 ml of trifluoroacetic acid, followed by stirring at room temperature for 5 hours. Subsequently, the reaction solution was concentrated under reduced pressure, and then, 2 ml of dichloromethane and 2 ml of triethylamine were added thereto. The mixture was stirred at room temperature for 5 minutes, and this was then concentrated under reduced pressure. The residue was dissolved in 10 ml of dichloroethane, and then, 278 mg of 3,4-dichlorobenzaldehyde and 242 mg of sodium triacetoxyborohydride were added thereto while being cooled by ice, followed by stirring at room temperature overnight, Subsequently, Water was added to the reaction solution, the mixture was stirred, and the insoluble precipitate was removed by filtration. The filtrate was dissolved in dichloromethane. The solution was washed with a saturated aqueous solution of sodium chloride, and then dried over magnesium sulfate. The magnesium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: methanol = 20: 1) to obtain 252 mg (yield: 41.1%) of light yellow powder, (R) -2- (4'- (4 - (3,4-dichlorobenzyl) piperazin-1-yl) biphenyl-4-yloxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 222.6 ° C-225.1 ° C (decomposition) Example 1505 (R) -2-methyl-6-nitro-2- (4- (4- (4- (4-trifluoromethoxyphenoxy) phenylamino) piperidin-1- il) phenoxymethyl) -2, 3-dihydroimidazo [2, 1-b] oxazole 376 mg of 4- (4-trifluoromethoxyphenoxy) aniline and 453 mg of sodium triacetoxyborohydride were added to a solution of dichloroethane (10 ml) containing 400 mg of (R) - 2-methyl-6-nitro-2- (4- (4-oxopiperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. The mixture was stirred at room temperature overnight. Subsequently, a saturated aqueous solution of sodium bicarbonate was added to the reaction solution, followed by repeated extraction with dichloromethane. The organic layer was dried over magnesium sulfate, and this was then filtered. The filtrate was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (dichloromethane: methanol = 20: 1). The resulting product was recrystallized from a mixed solvent consisting of dichloromethane and diisopropyl ether to obtain 650 mg (yield: 83.2%) of white powders, (R) -2-methyl-6-nitro-2- (4 - (4- (4- (4-trifluoromethoxyphenoxy) phenylamino) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 198.6 ° C-201.1 ° C (decomposition) Example 1506 (R) -2-methyl-6-nitro-2- (4- (4- (N-methyl-N- (3- (4-trifluoromethoxyphenoxy) ) propyl) amino) piperidin-1-yl) phenoxymethyl) -2, 3-dihydroimidazo [2, 1-b] oxazole 237 mg of (R) -2-methyl-6-nitro-2- (4- (4- (3- (4-trifluoromethoxyphenoxy) propylamino) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole was dissolved in a mixed solvent consisting of 10 ml of dichloromethane and 10 ml of methanol . Subsequently, 0.15 ml of an aqueous solution of 30% formaldehyde, 71.4 mg of sodium cyanotriborohydrate, and 0.01 ml of acetic acid were added to the mixture, followed by stirring at room temperature overnight. Subsequently, a saturated aqueous solution of sodium bicarbonate was added to the reaction solution, followed by repeated extraction with dichloromethane. The organic layer was dried over magnesium sulfate, and this was then filtered. The filtrate was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (dichloromethane: methanol = 20: 1). The resulting product was recrystallized from a mixed solvent consisting of dichloromethane and diisopropyl ether to obtain 215 mg (yield: 88.7%) of yellow fine powders, (R) -2-methyl-6-nitro-2- ( 4- (4- (N-methyl-N- (3- (4-trifluoromethoxyphenoxy) propyl) amino) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 167 4 ° C-170. 2 ° C Example 1507 (R) -2- (4- (4- (3,4-dichlorophenylamino) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole 628 mg of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole and 750 mg of 4- (4- (3,4-dichlorophenylamino ) piperidin-1-yl) phenol were dissolved in 10 ml of DMF, and then, 117 mg of sodium hydride was then added thereto, followed by stirring at 60 ° C for 20 minutes. Subsequently, the reaction solution was cooled to room temperature. Water was added to the reaction solution, and the insoluble precipitate was then removed by filtration. The filtrate was dissolved in dichloromethane, washed with a saturated aqueous solution of sodium chloride, and then dried over magnesium sulfate. The magnesium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (from dichloromethane: ethyl acetate = 9: 1 to 8: 2). The resulting product was then recrystallized from a mixed solvent consisting of dichloromethane and diisopropyl ether to obtain 441 mg (yield: 39%) of light yellow powder crystals, (R) -2- (4- (4- (3,4-dichlorophenylamino) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro -2, 3-dihydroimidazo [2, 1-b] oxazole. Melting point: 146 ° C-147. 4 ° C Example 1508 (R) -2-methyl-6-nitro-2- (4- (4- (N-methyl-N- (2- (4-trifluoromethoxyphenoxy) ethyl) amino) piperidin-1-yl ) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole 200 mg of (R) -2-methyl-6-nitro-2- (4- (4- (2- (4-trifluoromethoxyphenoxy) ethylamino) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole was dissolved in a mixed solvent consisting of 2 ml of dichloromethane and 2 ml of methanol. After 0.13 ml of an aqueous solution of 30% formaldehyde, 65 mg of sodium cyanotriborohydrate, and 0.07 ml of acetic acid were added to the mixture, followed by stirring at room temperature overnight. Subsequently, a saturated aqueous solution of sodium bicarbonate was added to the reaction solution, followed by repeated extraction with dichloromethane. The organic layer was dried over magnesium sulfate, and this was then filtered. The filtrate was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (dichloromethane: methanol = 20: 1). The resulting product was recrystallized from a mixed solvent consisting of dichloromethane and diisopropyl ether to obtain 155 mg (yield: 75.7%) of white powders, (R) -2-methyl-6-nitro-2- (4 - (4- (N-methyl-N- (2- (4-trifluoromethoxyphenoxy) ethyl) amino) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 185.7 ° C-187.7 ° C Example 1509 (R) -2 ~ methyl-6-nitro-2- (4- (4- (4- (4-trifluoromethoxyphenyl) piperazin-1-yl) piperidin-1 -yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole 145 mg of 1-trifluoromethoxyphenylpiperazine, 273 mg of sodium triacetoxyborohydride, and 0.061 ml of acetic acid were added to a solution of acetonitrile (15 ml) containing 200 mg of (R) -2-methyl-6-nitro-2- (4- (4-oxopiperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole, followed by stirring at room temperature for 11 days. Subsequently, a saturated aqueous solution of sodium bicarbonate was added to the reaction solution, followed by repeated extraction with dichloromethane. The organic layer was dried over magnesium sulfate, and this was then filtered. The filtrate was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (dichloromethane: methanol = 20: 1). The resulting product was recrystallized from isopropyl alcohol to obtain 143 mg (yield: 44.2%) of white powders, (R) -2-methyl-6-nitro-2- (4- (4- (4- (4 -trifluoromethoxyphenyl) piperazin-lyl) piperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 279 ° C-281 ° C Example 1510 (R) -2- (4- (4- (3,5-dichlorophenylamino) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2 , 3-dihydroimidazo [2,1-b] oxazole 1.82 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole and 2.02 g of 4- (4 - (3,5-dichlorophenylamino) piperidin-1-yl) phenol were dissolved in 20 ml of DMF, and then, 264 mg of sodium hydride was added thereto, followed by stirring at 60 ° C for 20 minutes. Subsequently, the reaction solution was cooled to room temperature. Water and ethyl acetate were added to the reaction solution, the mixture was stirred, and the insoluble precipitate was then removed by filtration. The filtrate was dissolved in dichloromethane, washed with a saturated aqueous solution of sodium chloride, and then dried over magnesium sulfate. The magnesium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (from dichloromethane: ethyl acetate = 9: 1 to dichloromethane: methanol = 20: 1). The resulting product was then recrystallized from a mixed solvent consisting of ethyl acetate and diethyl ether to obtain 1.19 g (yield: 38%) of light yellow powder crystals., (R) -2- (4- (4- (3,5-dichlorophenylamino) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2,1-b] oxazole . Melting point: 122 ° C-124 ° C Example 1511 (R) -2- (4- (4- (4- (4-chlorophenyl) piperazin-1-yl) piperidin-1-yl) phenoxymethyl) -2- methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole 10 ml of a 20% aqueous sodium carbonate solution was added an aqueous solution (10 ml) containing 290 mg of dichlorohydrate 1- (4-chlorophenyl) piperazine, and Subsequently, ultrasonic waves are applied to the mixture. The resulting product was extracted with dichloromethane, and dried over sodium sulfate. Subsequently, the solvent was removed under reduced pressure. The residue was dissolved in 15 ml of dichloroethane. Subsequently, 200 mg of (R) -2-methyl-6-nitro-2- (4- (4-oxopiperidin-1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole, 341 ml of sodium triacetoxyborohydride, and 0.092 ml of acetic acid were added to the mixture, followed by stirring at room temperature for 24 hours. Subsequently, a 20% aqueous sodium carbonate solution was added to the reaction solution, and the mixture was then concentrated under reduced pressure. Water was added to the residue, and the insoluble precipitate was collected by filtration. The precipitate was washed with water and then dried. The resulting product was then recrystallized from isopropyl alcohol to obtain 232 mg (yield: 78.1%) of light yellow powders, (R) -2- (4- (4- (4- (4-chlorophenyl) piperazine-1 -yl) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 247 ° C-249 ° C Example 1512 (R) -2-methyl-2- (4- (4- (4- (N-methyl-N- (4-chlorophenyl) amino) piperidin-1- il) piperidin-1-yl) phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole 241 mg of 4- (N-methyl-N- (4-chlorophenyl) amino) piperidine, 341 mg of sodium triacetoxyborohydride, and 0.092 ml of acetic acid were added to a dichloroethane solution (15 ml) containing 200 mg of (R) -2-methyl-6-nitro-2- (4- (4-oxopiperidin- 1-yl) phenoxymethyl) -2,3-dihydroimidazo [2,1-b] oxazole. The mixture was stirred at room temperature for 20 hours. Subsequently, a 20% aqueous sodium carbonate solution was added to the reaction solution, followed by repeated extraction with dichloromethane. The organic layer was dried over sodium sulfate, and this was then filtered. The filtrate was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (dichloromethane: methanol = 20: 1). The resulting product was then recrystallized from a mixed solvent consisting of dichloromethane and diethyl ether to obtain 105 mg (yield: 33.6%) of white powders, (R) -2-methyl-2- (4- (4 - (4- (N-methyl-N- (4-chlorophenyl) amino) piperidin-1-yl) piperidin-1-yl) phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole . Melting point: 230.8 ° C-232 ° C Example 1513 (R) -2-methyl-2- (4- (4- (4- (N-methyl-N- (4-trifluoromethoxyphenyl) amino) piperidin-1- il) piperidin-1-yl) phenoxymethyl) -6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole 283 mg of 4- (N-methyl-N- (4-trifluoromethoxyphenyl) amino) piperidine, 328 mg of sodium triacetoxyborohydride, and 0.089 ml of acetic acid were added to a solution of dichloroethane (15 ml) containing 192 mg of (R) -2-methyl-6-nitro-2- (4- (4-oxopiperidin- 1-yl) phenoxymethyl) -2,3-dihydroimidazo [2, 1-b] oxazole, followed by stirring at room temperature for 14 hours. Subsequently, a 20% aqueous sodium carbonate solution was added to the reaction solution, followed by repeated extraction with dichloromethane. The organic layer was dried over sodium sulfate, and this was then filtered. The filtrate was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (dichloromethane: methanol = 20: 1). The resulting product was recrystallized from a mixed solvent consisting of dichloromethane and diethyl ether to obtain 153 mg (yield: 47.1%) of yellow powders., (R) -2-methyl-2- (4- (4- (4- (N-methyl-N- (4-trifluoromethoxyphenyl) amino) piperidin-1-yl) piperidin-1-yl) phenoxymethyl) -6 -nitro-2, 3-dihydroimidazo [2, 1-b] oxazole. Melting point: 196 ° C-197 ° C Example 1514 (R) -2- (4- (4- (4-propylphenylamino) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2, 3 -dihydroimidazo [2, 1-b] oxazole 1.86 g of (R) -2-chloro-l- (2-methyl-2-oxiranylmethyl) -4-nitro-lH-imidazole and 1.9 g of 4- (4- ( 4-propylphenylamino) piperidin-1-yl) phenol were dissolved in 20 ml of DMF, and then, 269 mg of sodium hydride was then added thereto, followed by stirring at 50 ° C for 2 hours. Subsequently, the reaction solution was cooled to room temperature. Water and ethyl acetate were added thereto, the mixture was stirred, and the insoluble precipitate was then removed by filtration. The filtrate was dissolved in dichloromethane, washed with a saturated aqueous solution of sodium chloride, and then dried over magnesium sulfate. The magnesium sulfate was filtered off completely, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (from dichloromethane: ethyl acetate = 9: 1 to dichloromethane: methanol = 20: 1). The resulting product was then recrystallized from a mixed solvent consisting of ethyl acetate and diisopropyl ether to obtain 660 mg (yield: 21.9%) of light yellow powder crystals, (R) -2- (4- ( 4- (4-propylphenylamino) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 222 ° C-223 ° C Example 1515 (R) -2- (4- (4- (N-methyl-N- (4-propylphenyl) amino) piperidin-1-yl) phenoxymethyl) -2- methyl-6-nitro-2, 3-dihydroimidazo [2, 1-b] oxazole 300 mg of (R) -2- (4- (4- (4-propylphenylamino) piperidin-1-yl) phenoxymethyl) -2- Methyl-6-nitro-2,3-dihydroimidazo [2,1-b] oxazole was dissolved in a mixed solvent consisting of 4 ml of dichloromethane and 4 ml of methanol. Subsequently, 0.14 ml of an aqueous solution of 30% formaldehyde, 115 mg of sodium cyanotriborohydrate, and 0.1 ml of acetic acid were added to the mixture, followed by stirring at room temperature overnight. Subsequently, a 20% aqueous sodium carbonate solution was added to the reaction solution, followed by repeated extraction with dichloromethane. The organic layer was dried over magnesium sulfate, and this was then filtered. The filtrate was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (dichloromethane: methanol = 40: 1). The resulting product was recrystallized from a mixed solvent consisting of ethyl acetate and diisopropyl ether to obtain 258 mg (yield: 83.6%) of fine yellow powders, (R) -2- (4- (4- ( N-methyl-N- (4-propylphenyl) amino) piperidin-1-yl) phenoxymethyl) -2-methyl-6-nitro-2,3-dihydroimidazo [2, 1-b] oxazole. Melting point: 198 ° C-199 ° C Test Example 1 Antibacterial test (agar plate dilution method) The minimum inhibitory concentration of 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole obtained in sample 129 against M ^ _ tuberculosis H37Rv in a medium 7H11 (BBL Co.) was determined. A bacterial suspension of the strain used was previously prepared by culturing the bacteria in 7H9 medium (BBL Co.) Followed by calculation of viable cell quantity and cryopreservation at -80 ° C. The final viable cell amount of the preparation was approximately 10 6 CFU / ml. A 5- μL portion of the bacterial suspension was added to a 7H11 agar medium containing the test compound, cultured at 37 ° C for 14 days, and then tested to measure the maximum inhibitory concentration. The maximum inhibitory concentration against M. tuberculosis H37Rv was 0.0015 μg / mL. Test Example 2 Antibacterial test (agar plate dilution method) For the test compounds shown in the following table, the minimum inhibitory concentration against M. tuberculosis Kurono in 7H11 medium (BBL Co.) was determined. A bacterial suspension of the strain was prepared previously by culturing the bacteria in 7H9 medium (BBL Co.) Followed by calculating the viable cell quantity and cryopreservation at -80 ° C. The final viable cell amount of the preparation was approximately 106 CFU / mL. A 5-μL portion of the bacterial suspension was added to a 7H11 agar medium containing a test compound, it was cultivated at 37 ° C for 14 days, and then it was tested to measure the minimum inhibitory concentration. The results are shown in Table 183 below.

[Table 183] Minimum inhibitory concentration Test compound (μg / l) Compound of example 1 0.2 Compound of example 8 0.006 Compound of example 9 0.012 Compound of example 30 0.003 Compound of example 31 0.003 Compound of example 34 0.024 Compound of example 86 0.006 Compound of Example 88 0.024 Compound of example 99 0.0015 Compound of example 102 0.0015 Compound of example 105 0.012 Compound of example 107 0.024 Compound of example 108 0.0015 Compound of example 109 0.024 Compound of example 115 0.003 Compound of example 132 0.003 Compound of example 134 0.006 Compound of Example 145 0.024 Compound of example 178 0.024 Compound of example 185 0.024 Compound of example 211 0.024 Compound of example 214 0.024 Compound of example 222 0.024 Compound of example 225 0.024 Compound of example 230 0.012 Compound of example 240 0.024 Compound of example 324 0.024 Compound of Example 325 0.012 Compound of the example what 326 < 0.012 Compound of example 327 0.012 Compound of example 330 0.012 Compound of example 331 0.024 Compound of example 335 0.012 Compound of example 336 0.024 Compound of example 337 < 0.12 Compound of Example 338 0.024 (Continued) Minimum Inhibitory Concentration Test compound (μg / ml) Compound of example 339 0.006 Compound of example 340 0.024 Compound of example 341 0.006 Compound of example 344 0.006 Compound of example 345 0.012 Compound of example 346 0.024 Compound of example 349 O.012 Compound of example 349 0.012 Compound of example 359 0.012 Compound of example 362 0.012 Compound of example 368 0.024 Compound of example 369 0.006 Compound of example 370 0.012 Compound of example 371 0.006 Compound of example 373 0.012 Compound of example 377 0.024 Compound of example 382 0.024 Compound of example 384 0.024 Compound of Example 385 0.024 Compound of Example 388 0.012 Compound of Example 389 0.012 Compound of Example 390 0.012 Compound of Example 392 < 0.008 Compound of example 393 0.024 Compound of example 396 0.012 Compound of example 408 0.024 Compound of example 422 0.024 Compound of example 426 0.024 Compound of example 439 0.39 Compound of example 440 0.05 Compound of example 471 0.024 Compound of example 473 0.024 Compound of example 480 0.024 Compound of example 483 0.024 Compound of example 487 0.024 Compound of example 488 0.024 (Continued) Minimum inhibitory concentration Test compound (μg / ml) Compound of example 508 0.05 Compound of example 519 0.024 Compound of example 530 0.012 Compound of example 602 0.024 Compound of example 612 0.024 Compound of example 614 0.024 Compound of example 646 0.012 Compound of example 647 0.024 Compound of example 648 0.024 Compound of example 660 0.024 Compound of example 663 0.05 Compound of example 664 0.024 Compound of example 665 0.024 Compound of example 679 0.024 Compound of example 694 0.1 Compound of example 695 0.024 Compound of example 698 0.012 Compound of example 721 0.024 Compound of example 738 0.003 Compound of example 739 0.012 Compound of example 756 0.05 Compound of example 761 0.78 Compound of example 768 0.012 Compound of example 753 0.024 Compound of example 780 0.006 It is noted that in relation to this date, the best method known by the applicant to carry out the aforementioned invention, is that which is clear from the present description of the invention.

Claims (35)

Claims: Having described the invention as above, the content of the following claims is claimed as property.

1. A 2,3-dihydroimidazo [2, 1-b] oxazole compound represented by the following general formula (I), an optically active form thereof, or a pharmacologically acceptable salt thereof: characterized in that R1 represents a hydrogen atom or a C6-C6 alkyl group, R1 and ~ (CH2) nR2 can be linked together with carbon atoms adjacent thereto, so as to form a spiro ring represented by the general formula (30): wherein RRR represents a piperidyl group [wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)], and R2 represents a group described in any of the following (a) to (y): ( a) a phenyl group (wherein, in the phenyl ring, at least one piperidyl group can be substituted [wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]); (b) a benzothiazolyloxy group (wherein, in the benzothiazole ring, at least one selected from the group consisting of the following (b-1) to (b-5) can be substituted: (b-1) a phenyl group [ wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can to be substituted], (b-2) a piperazinyl group [wherein, in the piperazine ring, at least one selected from the group consisting of a C1-C6 alkyl group phenyl (wherein, in the phenyl group, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a C2-C6 alkenyl group, phenyl (wherein, in the phenyl group, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), and a phenyl group (wherein, in the phenyl group, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), can be substituted] , (b-3) a piperidyl group [wherein, in the piperidine ring, at least one selected from the group consisting of an amino group (wherein, in the amino group, at least one selected from the group consisting of a group phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen , can be replaced] and a group C1-C6 alkyl can be substituted), a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), and a C1-C6 alkyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a group C1-C6 alkyl substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be 'substituted), a pyrrolyl group [, wherein, in the pyrrole ring, at least one selected from the group consists of a C1-C6 alkyl group and a C1-C6 alkyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted) can be substituted], and (b-5) a phenylthio group (wherein, on the phenyl ring, at least one selected from the group consists of a halogen atom, a C1-C6 alkyl group substituted or not substituted by halogen, and a C1-C6 alkoxy group substituted or not substituted by halogen, can be substituted)); (c) a quinolyloxy group (wherein, in the quinoline ring, at least one selected from the group consisting of the following (c-1) to (c-4) can be substituted: (c-1) a halogen atom , (c-2) a phenoxy group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and an alkoxy C1 group -C6 substituted or unsubstituted with halogen, can be substituted], (c-3) a piperazinyl group [wherein, in the piperazine ring, at least one selected from the group consisting of a C1-C6 alkyl group phenyl (in where, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C1-C6 alkyl group with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a phenyl group [wherein, on the phenyl ring, at least one group selected from the group consists of a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a substituted C1-C6 alkoxy group or not substituted by halogen, can be substituted), a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-C6 alkoxy group substituted or unsubstituted by halogen, can be substituted], and a group C2-C6 alkenyl phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted C1-C6 alkoxy group or not substituted by halogen, can be substituted], and can be substituted], and (c-4) a piperidyl group [wherein, in the piperidine ring, at least one selected from the following group can be substituted: an amino group (wherein , in the amino group, at least one selected from the group consisting of a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-C6 alkoxy group -C6 substituted or unsubstituted with halogen, can be substituted] and a C1-C6 alkyl group can be substituted); a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C 1 -C 6 alkyl group, and a substituted or unsubstituted C 1 -C 6 alkoxy group with halogen, it can be replaced); a C 1 -C 6 alkyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a C 1 -C 4 alkylenedioxy group, a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted); a C 1 -C 6 alkoxy phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or not substituted with halogen, can be substituted); a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, it can be replaced); a C 1 -C 6 alkyl naphthyl group; and a C1-C6 alkylidene group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-6 alkoxy group C6 substituted or unsubstituted with halogen, can be replaced)]); (d) a pyridyloxy group (wherein, in the pyridine ring, at least one selected from the group consisting of the following (d-1) and (d-2) can be substituted: (d-1) a piperidyl group [ where, in the piperidine ring, at least one selected from the group consisting of a phenoxy group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or not substituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a C1-C6 alkyl group substituted with C1-C6 alkoxy phenyl (wherein, on the phenyl ring, at least one selected from the a group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a C1-C6 alkyl phenoxy group (in where, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C 1 -C 6 alkyl group with halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen, can be replaced), and a group C 1 -C 6 alkyl phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted by halogen, and a substituted C 1 -C 6 alkoxy group or not replaced with halogen, can be replaced), can be replaced]; and (d-2) a piperazinyl group [wherein, in the piperazine ring, at least one selected from the group consisting of a C1-C6 alkoxycarbonyl group, a C1-C6 alkyl furyl group [wherein, in the furan ring , at least one phenyl group can be substituted (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and an alkoxy group C1 -C6 substituted or unsubstituted with halogen, can be substituted)], a C1-C6 alkyl pyridyl group [wherein, in the pyridine ring, at least one selected from the group consisting of a furyl group and a phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)], a C1-C6 alkyl group benzothienyl (wherein, in the benzothiophene ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen , may be substituted), a C2-C6 alkenyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a C 1 -C 6 alkyl benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a group C 1 -C 6 alkyl substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen, can be substituted], a C 2 -C 6 alkenyl benzofuryl group [wherein, in the benzofuran ring, at least one selected of the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], a C1-C6 alkyl thiazolyl group [in where, in the thiazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen , and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)], a C1-C6 alkyl phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom , a C 1 -C 6 alkyl group substituted or not substituted by halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted by halogen, can be substituted), a C 1 -C 6 alkyl indolyl group (wherein, in the indole ring, minus one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), and a C1-C6 alkyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a benzofuryl group, a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be replaced) can be replaced]); (e) a 1, 2, 3, 4-tetrahydroquinolyoxy group (wherein, in the 1, 2, 3, 4-tetrahydroquinoline ring, at least one selected from the group consisting of an oxo group, a phenyl group [wherein , in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted ], and a C1-C6 alkyl group phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and an alkoxy group C1-C6 substituted or not substituted with halogen, can be replaced], can be replaced); (f) a 1, 2, 3, 4-tetrahydronaphthyloxy group (wherein, in the 1, 2, 3, 4-tetrahydronaphthalene ring, at least one oxo group can be substituted); (g) a 2H-chromenoxide group (wherein, in the 2H-chromene ring, at least one oxo group can be substituted); (h) a naphthyloxy group (wherein, in the naphthalene ring, at least one piperidyl group can be substituted [wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, in the phenyl ring, less one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]); (i) a 1,2,3,4-tetrahydroisoquinolyoxy group (wherein, in the 1, 2, 3, 4-tetrahydroisoquinoline ring, at least one selected from the group consisting of a C1-C6 alkoxycarbonyl group, an alkyl group C1-C6 phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be substituted], and a phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], can be substituted); (j) a group -NR22R23 (wherein R22 represents a hydrogen atom or a C1-C6 alkyl group, and R23 represents at least one selected from the following (j-1) to (j-5): (j-1) ) a phenyl group [wherein, in the phenyl ring, at least one piperidyl group is substituted (wherein, in the piperidine ring, at least one phenoxy group can be substituted [wherein, in the phenyl ring, at least one selected of the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted])], (j-2) a C 1 -C 6 alkyl group phenyl [wherein, in the phenyl ring, at least one group selected from the group consisting of a piperidyl group (wherein, in the piperidine ring, a phenoxy group is substituted [wherein, in the phenyl ring , at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or not substituted substituted with halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen, can be substituted]) and a group -NR R (wherein R represents a hydrogen atom or C 1 -C 6 alkyl group, and R 25 represents a group C2-C6 alkenyl phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted C1-C6 alkoxy group or not substituted by halogen, it can be substituted]), substituted], (j-3) a C1-C6 alkyl piperidyl group [wherein, in the piperidine ring, at least one phenyl group is substituted (wherein, in the ring phenyl, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)], ( j-4) a thiazolyl group [where, in the thiazole ring, at least s a group selected from the group consisting of a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a C1-C6 alkyl piperazinyl group (wherein, in the piperazine ring, at least one phenyl group can be substituted [wherein, in the phenyl ring , at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted]), and C1-C6 alkyl piperidyl group (wherein, in the piperidine ring, at least one phenoxy group can be substituted [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1 -C6 substituted or not substi With the halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted]), can be substituted], and (j-5) a C2-C6 alkenyl group phenyl (wherein, in the phenyl ring , at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)); (k) a benzoxazolyloxy group (wherein, in the benzoxazole ring, at least one selected from the group consisting of a piperazinyl group [wherein, in the piperazine ring, at least one selected from the group consisting of an alkyl group C1 -C6 phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, can be substituted), and a C2-C6 alkenyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a piperidyl group can be substituted (wherein, in the piperidine ring, at least one selected from the group consisting of an alkyl group C1-C6 phenyl [in don of, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted] and an amino group [wherein, in the amino group, at least one selected from the group consisting of a C1-C6 alkyl group and a phenyl group (wherein, in the phenyl ring, at least one selected from the group consists of an atom of 17 halogen, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted) can be substituted] can be substituted), and a phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted] , can be replaced); (1) a benzoimidazolyloxy group (wherein, in the benzoimidazole ring, at least one selected from the group consisting of a C1-C6 alkyl group, a phenyl group [wherein, in the phenyl ring, at least one selected from the group consists of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], a piperidyl group [where, in the piperidine ring , at least one phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen and a substituted C1-C6 alkoxy group or not substituted by halogen can be substituted), a piperazinyl group [wherein, in the piperazine ring, at least one C1-C6 alkyl group phenyl (wherein, on the phenyl ring, at least one selected from the group which consists of an atom of halogen, a C1-C6 alkyl group substituted or unsubstituted with halogen and a C1-C6 alkoxy group substituted or unsubstituted with halogen can be substituted) can be substituted] and a C1-C6 alkyl group phenyl [wherein, in the ring phenyl, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted by halogen, can be substituted], can be replaced); (m) a 1, 2, 3, 4-tetrahydroisoquinolyl group (wherein, in the 1, 2, 3, 4-tetrahydroisoquinoline ring, at least one selected from the group consisting of the following (m-1) and (m-2) can be substituted: (ml) an amino group [wherein, in the amino group, at least one selected from the group consisting of a C1-C6 alkyl group, a phenyl group (wherein, in the ring phenyl, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), and a C1-C6 alkyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom , a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), and can be substituted] and (m-2) a phenoxy group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted] ); (n) a piperidyl group (wherein, in the piperidine ring, at least one selected from the group consisting of the following (n-1) to (n-4) can be substituted: (n-1) a phenyl group [ wherein, in the phenyl ring, at least one group -NR R is substituted (wherein R represents a hydrogen atom or C1-C6 alkyl group, and R27 represents a phenyl group [wherein, at the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted])], (n-2) ) a group -W? NR28R29 [wherein x represents a C1-C6 alkylene group, R28 represents a hydrogen atom or C1-C6 alkyl group, and R29 represents a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and an alkoxy group C 1 -C 6 substituted or unsubstituted with halogen, can be substituted), (n-3) a C 1 -C 6 alkoxy group in which two phenyl groups are substituted [wherein, in the phenyl ring, at least one selected from the group consists of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], and (n-4) a C1-6 alkyl group C6 phenyl [wherein, in the phenyl group ring, at least one phenyl group is substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted C1-C6 alkyl group) or not substituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]); (o) a piperazinyl group (wherein, in the piperazine ring, at least one selected from the following group is substituted: a C1-C6 alkyl group in which two phenyl groups are substituted [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], a C1-C6 alkyl group phenyl [wherein, in the phenyl ring, at least one phenoxy group is substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C1-C6 alkyl group) with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, is substituted)], a thiazolyl group (wherein, in the thiazole ring, at least one phenyl group can be substituted), a C1-C6 alkyl group phenoxy (where, in the ring phenyl, at least one selected from the group consisting of a phenyl group (wherein, on the phenyl ring, halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be substituted), a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a C 2 alkenyl group -C6 phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, is substituted], and an imidazolyl group [wherein, in the imidazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom , a group alqui C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]); (p) a thiazolyl C1-C6 alkoxy group (wherein, in the thiazole ring, at least one type selected from the group consisting of the following (p-1) to (p-5) can be substituted: (p-1) ) a C1-C6 alkyl phenoxy group [where, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted ], (p-2) an anilino C1-C6 alkyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted by halogen, can be substituted], (p-3) a C1-C6 alkyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-C6 alkoxy group substituted or unsubstituted by halogen, can be substituted], (p-4) a C1-C6 alkyl piperazinyl group [in where, in the piperazine ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), and (p-5) a C1-C6 alkyl piperidyl group [wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, in the phenyl ring, at least one selected from the a group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]); (q) an 8-azabicyclo [3.2.1] octyl group (wherein, in the 8-azabicyclo [3, 2, 1] octane ring, at least one phenoxy group can be substituted [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted]); (r) a group represented by the following chemical formula (31): [wherein X represents a halogen atom, or a C 1 -C 6 alkyl group substituted with amino which can have a C 1 -C 6 alkyl group as a substituent, m represents an integer between 0 and 3, and R 3 represents a group described in any of the following (i) through (xxii): (i) a group - (W) or -NR4R5 (wherein W represents a group -CO- or a C1-C6 alkylene group, or represents 0 or 1, R4 represents a hydrogen atom, a C1-C6 alkyl group, or a phenylcarbamoyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], and R5 represents: a C1-C6 alkoxycarbonyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of one atom of halogen, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-6 alkoxy group C6 substituted or unsubstituted with halogen, can be replaced]; a C2-C6 alkenylcarbonyl phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be replaced]; a C2-C6 alkenyl group phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be replaced]; a C1-C6 alkyl piperidyl group [wherein, in the piperidine ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]; a C1-C6 alkyl group phenyl (wherein, on the phenyl ring, at least one phenyl group is substituted (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1 -C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)); a C 1 -C 6 alkyl benzofuryl group (wherein, in the benzofuran ring, at least one C 1 -C 6 alkyl group substituted or unsubstituted with halogen can be substituted); a C1-C6 alkyl group piperidinylcarbonyl [wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted); or a group represented by the following chemical formula (32): wherein R6 represents: a C1-C6 alkyl group; a phenyl group (wherein, on the phenyl ring, at least one selected from the following group can be substituted: a C1-C4 alkylenedioxy group, a cyano group, a nitro group, an amino group which can have a C1-C6 alkyl group as a substituent, an amino-substituted sulfonyl group which may have a C1-C6 alkyl group as a substituent, a C1-C6 alkoxycarbonyl group, a C1-C6 alkylthio group, a phenoxy group, a C1-C6 alkoxy phenyl group, a pyrrolidinyl group [wherein, in the pyrrolidine ring, at least one oxo group can be substituted], an imidazolyl group, an isoxazolyl group, an oxazolyl group, a C1-C6 alkyl group phenyl, a phenyl group, a C1-6 alkyl group C6 amino which may have a C1-C6 alkyl group as a substituent, a C1-C6 alkoxy pyrrolidinyl group, a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted C1-C6 alkoxy group or not replaced with halogen); a C 1 -C 6 alkoxycarbonyl phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted by halogen, and a C 1 -C 6 alkoxy group substituted or not substituted with halogen, can be substituted); a C 1 -C 6 alkyl benzofuryl group (wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or not substituted with halogen, can be substituted); a C2-C6 alkenyl benzofuryl group (wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be substituted); a C1-C6 alkyl phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be substituted); a C 1 -C 6 alkyl thiazolyl group (wherein, in the thiazole ring, at least one phenyl group can be substituted [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted]); a C 1 -C 6 alkyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a phenyl group (wherein, on the phenyl ring, a halogen atom, a substituted C 1 -C 6 alkyl group or not substituted by halogen, and a C1-C6 alkoxy group substituted or unsubstituted by halogen, can be substituted), a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a substituted C1-C6 alkoxy group or not substituted with halogen, can be substituted]; a C 1 -C 6 alkyl pyridyl group [wherein, in the pyridine ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]; a C1-C6 alkoxycarbonyl group; a benzoyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C 1 -C 6 alkyl group, and a substituted or unsubstituted C 1 -C 6 alkoxy group with halogen, it can be replaced); a phenylcarbamoyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, it can be replaced); a C 1 -C 6 alkyl benzothienyl group (wherein, in the benzothiophene ring, at least one halogen atom can be substituted); an indolyl C1-C6 alkyl group (wherein, in the indole ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be substituted); a 4H-1, 3-benzodioxinyl group (wherein, in the 4H-1, 3-benzodioxine ring, at least one halogen atom can be substituted); benzothienyl group; a naphthyl group; a quinolyl group; a benzothiazolyl group (wherein, in the benzothiazole ring, at least one C1-C6 alkyl group can be substituted); a 2, 3-dihydro-lH-indenyl group (wherein, in the 2, 3-dihydro-lH-indan ring, at least one oxo group can be substituted); or a 9H-fluorenyl group or C2-C6 alkenyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)); (ii) a group represented by the following chemical formula (33): (where W and I are the same as above, a dotted line represents that the lcan be a double bond, and when the dotted line represents a double bond, this means that only R8 is substituted, R7 represents a hydrogen atom, group hydroxyl, C1-C6 alkoxy group, or phenyl group [wherein, in the phenyl ring, halogen can be substituted]; and R8 represents a group described in any of the following (1) to (63): (1) a group C 1 -C 6 alkyl substituted with C 1 -C 6 alkoxy phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a C 1 -C 4 alkylenedioxy group, a halogen atom, a cyano group, a phenyl group, a C1-C6 alkoxy group phenyl, a C2-C6 alkenyl group phenyl, a phenoxy group, a C1-C6 alkylthio group, a C1-C6 alkoyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, it can be substituted); (2) a C 1 -C 6 alkoxy phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a cyano group, a phenyl group, a C1-C6 alkoxycarbonyl group, a phenoxy group, a C1-C6 alkylthio group, a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-C6 alkoxy group substituted or unsubstituted by halogen, can be substituted); (3) a C2-C6 alkenyloxy phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and an alkoxy group C1-C6 substituted or unsubstituted with halogen, can be substituted); (4) a group - (W) O-NRA10 (where W and I are the same as above, and R9 and R10 each identically or differently represent: a hydrogen atom; a C1-C6 alkyl group which may have a group hydroxyl as a substituent, a C1-C6 alkanoyl group, a C1-C6 alkoxycarbonyl group, a C1-C6 alkoxycarbonyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted by halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted by halogen, can be substituted]; a phenyl group [in the phenyl ring, at least one selected from the following group can be substituted as a substituent: a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, a C1-C6 alkoxy group substituted or unsubstituted by halogen, an amino group which may have, as a substituent, a group selected from the group consisting of group consisting of a gru for C 1 -C 6 alkanoyl and a C 1 -C 6 alkyl group, a C 1 -C 6 alkoxycarbonyl group, a phenyl group, a phenoxy group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted by halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted by halogen, can be substituted), an aminosulfonyl group, a 1, 2, 3, 4-tetrahydroquinolyl group (wherein , in ring 1, 2, 3, 4-tetrahydroquinoline, at least one oxo group can be substituted as a substituent), a C1-C6 alkylsulfonyl group, a C3-C8 cycloalkyl group, a nitro group, a cyano group, a C1-C6 alkylthio group, a phenylsulfonyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and an alkoxy group C1 -C6 substituted or unsubstituted with halogen, can be substituted), a C1-alkyl group -C6 substituted with hydroxyl group, and a group represented by the following chemical formula (34): (wherein i represents a C1-C6 alkylene group, and R11 and R12 each identically or differently represent a C1-C6 alkoxy group)]; a C 1 -C 6 alkyl group phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a C 1 -C 4 alkylenedioxy group, a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be substituted), a group -N (R11A) R12A (wherein R11A and R12A each identically or differently represent a hydrogen atom, C1-C6 alkyl group, or phenyl group, and R11A and R12A can be linked one to the other together with nitrogen atoms adjacent to it directly or through nitrogen, oxygen or sulfur atoms, so that they form a 5-7 membered saturated heterocyclic ring), a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), an alkoxy C1 group -C6 phenyl, a C1-C6 alkoxy group substituted with amino group which may have a C1-C6 alkyl group as a substituent, a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted substituted with halogen, can be replaced as a substituent]; a C 1 -C 6 alkyl benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or not substituted with halogen, can be replaced]; a phenylsulfonyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, and a C1-C4 alkylenedioxy can be substituted]; a phenoxycarbonyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, it can be replaced]; a C2-C6 alkenyl group phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be replaced]; a C1-C6 alkyl group substituted with C1-C6 alkoxy; a C2-C6 alkenyl group; a C2-C6 alkanoyl group substituted with C1-C6 alkoxy; a C1-C6 alkyl group substituted with C3-C8 cycloalkyl; a C 1 -C 6 alkyl phenoxy group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or not substituted with halogen, can be replaced]; a benzoyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, it can be replaced]; a phenylcarbamoyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, it can be replaced]; a pyridyl group; a C1-C6 alkyl pyridyl group; a C1-C6 alkyl imdazolyl group; a 1, 2, 3, 4-tetrahydroquinolyl group [wherein, in the 1, 2, 3, 4-tetrahydroquinoline ring, at least one selected from the group consisting of an oxo group and a C1-C6 alkyl group can be substituted as a substituent]; a quinolyl group; an indolyl group; an amino group which may have a C1-C6 alkyl group as a substituent; an indazolyl group; a naphthyl group; a C3-C8 cycloalkyl group; a C 1 -C 6 alkyl group substituted with amino which may have a C 1 -C 6 alkyl group as a substituent; a C 1 -C 6 alkyl group substituted with cyano; a C 1 -C 6 alkyl group substituted with furyl; a group of the formula (35) (wherein RR represents a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and an alkoxy group C1-C6 substituted or unsubstituted with halogen, can be substituted)); or a C1-C6 alkyl group substituted with piperazinyl [wherein, in the piperazine ring, at least one phenyl group can be substituted as a substituent (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)], in addition, R9 and R10 can be linked to each thereof either directly or through nitrogen atoms, oxygen or sulfur, so that they form a 1,2,3,4-tetrahydroisoquinolyl group, isoindolyl group, or saturated 5-7 membered heterocyclic ring, wherein, in the heterocyclic ring, at least one selected from the following group can be substituted: a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, a C1-C6 alkoxy group substituted or unsubstituted by halogen, a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a phenyl group, a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], a benzoyl group [in Where, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], a C1-C6 alkyl pyridyl group, a C3-C8 cycloalkyl group, a C1-C6 alkyl phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a C1-C4 alkylenedioxy group, an halogen, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-C6 alkoxy group substituted or unsubstituted by halogen, can be substituted], a C1-C6 alkyl piperidyl group, a piperidyl group, an alkoxy C1 group -C6 phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, it can be replaced], a phenoxy group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], an amino group wherein at least one selected from the group consisting of a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], a C1-C6 alkyl group, and a C1-C6 alkyl phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted], can be replaced as a subs is a benzoxazolyl group, a C2-C6 alkenyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), and a benzoimidazolyl group); (5) a C 1 -C 6 alkyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be substituted), a C 1 -C 6 alkyl group substituted or unsubstituted with halogen, and a C 1 -C 6 alkoxy group substituted or unsubstituted with halogen, can be substituted); (6) a carbamoyloxy group (wherein, in the amino group, at least one selected from the group consisting of a C1-C6 alkyl group and a phenyl group [wherein, on the phenyl ring, at least one selected from the group consists of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted] can be substituted); (7) a C1-C6 alkyl group substituted with carbamoyloxy (wherein, in the amino group, at least one selected from the group consisting of a C1-C6 alkyl group, a C1-C6 alkyl group 90! phenyl, a C3-C8 cycloalkyl group, a naphthyl group, a 2,3-dihydro-lH-indenyl group, a 2,3-dihydrobenzofuryl group, and a phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a C1-C4 alkylenedioxy group, a cyano group, a phenoxy group, a C1-C6 alkylthio group, a C1-C6 alkanoyl group, a phenyl group , a C1-C6 alkyl group phenyl, a halogen atom, a Cl-ClO alkyl group substituted or unsubstituted with halogen, and an alkoxy group Cl-ClO substituted or unsubstituted with halogen, can be replaced], can be substituted); (8) a C 1 -C 6 alkyl phenoxy group (wherein, on the phenyl ring, at least one selected from the following group can be substituted: a halogen atom, a C 1 -C 4 alkylenedioxy group, a C 1 -C 6 alkoxycarbonyl group; phenyl group, a phenoxy group, a pyrrolyl group, a benzothiazolyl group, a 1,2,4-triazolyl group, an imidazolyl group, an isoxazolyl group, a benzoxazolyl group, a benzotriazolyl group, a cyano group, a nitro group, a C2-C6 alkenyl group, a C1-C6 alkanoyl group, a C1-C6 alkyl group substituted with C1-C6 alkoxycarbonyl, a C1-C6 alkyl group substituted with C1-C6 alkanoyl, a group -N (R11B) R12B (wherein R11B and R12B each identically or differently represent a hydrogen atom, C1-C6 alkyl group, C1-C6 alkanoyl group, or phenyl group, and R11B and R12B can be linked together with nitrogen atoms adjacent thereto directly or through of nitrogen, oxygen or sulfur atoms, so that they form an anil the 5-7 membered saturated heterocyclic, wherein, in the heterocyclic ring, at least one selected from the group consisting of a C1-C6 alkoxycarbonyl group and an amino group [wherein, in the amino group, at least one selected from a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, it can be substituted) and a C 1 -C 6 alkyl group can be substituted] can be substituted); a C 1 -C 6 alkoxy phenyl group; a C1-C6 alkyl group phenyl; a C1-C6 alkylthio group; a C3-C8 cycloalkyl group; a C1-C6 alkyl group substituted or unsubstituted with halogen; and a Cl-ClO alkoxy group substituted or unsubstituted with halogen); (9) a C 1 -C 6 alkyl tetrahydropyranyloxy group; (10) a C 1 -C 6 alkyl group substituted with hydroxyl; (11) a C 1 -C 6 alkyl group substituted with C 1 -C 6 alkoxy furyl (wherein, in the furan ring, at least one C 1 -C 6 alkoxycarbonyl group can be substituted); (12) a C1-C6 alkyl group substituted with C1-6 alkoxy tetrazolyl (wherein, in the tetrazole ring, at least one selected from the group consisting of a phenyl group (wherein, in the phenyl ring, at least one selected of the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), a C1-C6 alkyl group phenyl, and a C1-C6 alkyl group, C3-C8 cycloalkyl, can be substituted); (13) a C 1 -C 6 alkyl group substituted with C 1 -C 6 alkoxy isoxazolyl (wherein, in the isoxazole ring, at least one C 1 -C 6 alkyl group can be substituted); (14) a C 1 -C 6 alkyl group substituted with benzothienyl Cl-C 6 alkoxy (wherein, in the benzothiophene ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted); (15) a C1-C6 alkyl group substituted with C1-C6 alkoxy, 1,3,4-oxadiazolyl (wherein, in the 1,3,4-oxadiazole ring, a phenyl group can be substituted [wherein, in the ring phenyl, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted]); (16) a C1-C6 alkyl group substituted with C2-C6 alkynyloxy; (17) a C1-C6 alkyl group substituted with C1-C6 alkoxy naphthyl; (18) a C1-C6 alkyl group substituted with Cl-Cβ 1,2,4-oxadiazolyl alkoxy [wherein, in the 1,2,4-oxadiazole ring, a phenyl group can be substituted]; (19) a Cl-Cß alkyl group substituted with Cl-C 6 alkoxy pyridyl [wherein, in the pyridine ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted]; (20) a C1-C6 alkyl group substituted with Cl-Cβ thiazolyl alkoxy [wherein, in the thiazole ring, at least one selected from the group consisting of a phenyl group (wherein, in the phenyl ring, at least one selected of the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted) and a Cl-Cß alkyl group can be substituted. replaced]; (21) a Cl-Cß alkyl group substituted with Cl-Cβ 1,2,3,4-tetrahydronaphthyl alkoxy [wherein, in the 1,2,3,4-tetrahydronaphthalene ring, at least one Cl-Cß alkyl group can be to be replaced]; (22) a Cl-Cß alkyl group substituted with Cl-Cβ carbamoyl alkoxy [wherein, in the amino group, at least one selected from the group consisting of a C3-C8 cycloalkyl group and a phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted) can be replaced]; (23) a Cl-Cß alkyl group substituted with Cl-Cβ-benzofuryl alkoxy [wherein, in the benzofuran ring, at least one cyano group can be substituted]; (24) a C 1 -C 6 alkyl benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a C 1 -C 6 alkyl group substituted or unsubstituted with halogen, and an alkoxy group C1-C6 substituted or unsubstituted with halogen, can be substituted]; (25) a phenoxy group [wherein, on the phenyl ring, at least one selected from the group consisting of a C1-C6 alkoxy phenyl group, a C3-C8 cycloalkyl group, a C7-C10 alkoxy group, and a phenoxy group , is replaced]; (26) a naphthyloxy group; (27) a 2, 3-dihydrobenzofuryloxy group [wherein, in the 2, 3-dihydrobenzofuran ring, at least one oxo group can be substituted]; (28) a benzothiazolyloxy group [wherein, in the benzothiazole ring, at least one C1-C6 alkyl group can be substituted]; (29) a 1, 2, 3, 4-tetrahydronaphthyloxy group [wherein, in the 1, 2, 3, 4-tetrahydronaphthalene ring, at least one oxo group can be substituted]; (30) a dibenzofuryloxy group; (31) a quinolyloxy group; (32) a Cl-Cβ alkoxy furyl group [wherein, in the furan ring, at least one Cl-Cβ alkoxycarbonyl group can be substituted]; (33) a Cl-Cβ tetrazolyl alkoxy group [wherein, in the tetrazole ring, at least one selected from the group consisting of a Cl-Cβ alkyl phenyl group and a Cl-Cβ C3-C8 cycloalkyl alkyl group can be substituted]; (34) a 1,2-, 4,4-oxadiazolyl C1-C 1 alkoxy group [wherein, in the 1,2,4-oxadiazole ring, a phenyl group can be substituted (wherein, in the phenyl ring, at least one selected of the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted)]; (35) a Cl-Cβ benzothienyl alkoxy group [wherein, in the benzothiophene ring, at least one halogen atom can be substituted]; (36) a C 1 -C 6 alkoxy isoxazolyl group [wherein, in the isoxazole ring, at least one Cl-Cß alkyl group can be substituted]; (37) a Cl-Cβ 1, 3, 4-oxadiazolyl alkoxy group [wherein, in the 1,3,4-oxadiazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least a C1-C6 alkyl group can be substituted)]; (38) a C1-C6 alkoxy naphthyl group; (39) a C1-C6 alkoxy pyridyl group (wherein, in the pyridine ring, at least one C1-C6 alkyl group substituted or unsubstituted with halogen can be substituted); (40) a thiazolyl C1-C6 alkoxy group [wherein, in the thiazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]; (41) a 1, 2, 3, 4-tetrahydronaphthyl C1-C6 alkoxy group (wherein, in the 1, 2, 3, 4-tetrahydronaphthalene ring, at least one C1-C6 alkyl group can be substituted); (42) a C1-C6 alkoxy phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and an alkoxy group C1-C6 substituted or unsubstituted with halogen, can be substituted); (43) a Cl-Cβ carbamoyl alkoxy group [wherein, at the amino group, at least one selected from the group consisting of a C3-C8 cycloalkyl group and a phenyl group (wherein, at the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted) can be substituted]; (44) a C 1 -C 6 alkoxybenzofuryl group (wherein, in the benzofuran ring, at least one cyano group can be substituted); (45) an alkyl Cl-Cβ naphthyloxy group (wherein, in the naphthalene ring, at least one Cl-Cβ alkoxy group can be substituted); (46) a C 1 -C 6 alkyl benzothiazolyloxy group (wherein, in the benzothiazole ring, at least one C 1 -C 6 alkyl group can be substituted); (47) a C1-C6 alkyl quiniloxy group (wherein, in the quinoline ring, at least one C1-C6 alkyl group can be substituted); (48) a C1-C6 alkyl 2,3-dihydrobenzofyloxy group (wherein, in the 2, 3-dihydrobenzofuran ring, at least one selected from the group consisting of a C1-C6 alkyl group and an oxo group can be substituted ); (49) a C1-C6 alkyl group 1, 2, 3, 4-tetrahydronaphthyloxy (wherein, in ring 1, 2, 3, 4-tetrahydronaphthalene, at least one oxo group can be substituted); (50) a 2,3-dihydro-lH-indenyloxy C 1 -C 6 alkyl group (wherein, in the 2, 3-dihydro-1 H-indene ring, at least one oxo group can be substituted); (51) a C 1 -C 6 alkyl benzoxathiolanyloxy group (wherein, in the benzoxathiolane ring, at least one oxo group can be substituted); (52) an alkyl Cl-Cβ isoquinolyloxy group; (53) a Cl-Cβ pyridyloxy alkyl group; (54) a Cl-Cβ dibenzofuryloxy alkyl group; (55) a Cl-C 2 H-1-benzopyranyloxy alkyl group (wherein, in the 2 H-1-benzopyran ring, at least one oxo group can be substituted); (56) a C 1 -C 6 alkyl benzoisoxazolyloxy group; (57) a C 1 -C 6 alkyl group benzofurazanyloxy; (58) a C 1 -C 6 alkyl quinoxalyloxy group; (59) a C 1 -C 6 alkyl group substituted with Cl-Cβ alkoxy Cl-Cβ alkoxy; (60) a Cl-Cß alkyl group substituted with Cl-Cβ-thienyl alkoxy (wherein, in the thiophene ring, at least one halogen atom can be substituted); (61) a C1-C6 alkyl group substituted with C2-C6 alkenyloxy phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C3 alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted); (62) a C1-C6 alkyl group substituted with C1-C6 alkoxy quinolyl; and (63) a Cl-Cß alkyl group substituted with Cl-Cβ piperidylcarbonyl alkoxy, and in addition, R7 and R8 together can form a group = C (R29) (R30), wherein R29 and R30 each identically or differently represent a hydrogen atom, Cl-Cß alkyl group, or phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or not substituted by halogen, can be substituted]); (iii) a group represented by the following chemical formula (36): (where Wi I is the same as above, and R, 13 represents: a 2, 3-dihydro-lH-indenyl group, a benzothienyl group, a C2-C10 alkenyl group phenyl [wherein, on the phenyl ring, less one selected from the group consisting of a halogen atom, a C1-C4 alkylenedioxy group, a C1-C6 alkylthio group, a benzoyl group, a cyano group, a nitro group, a C2-C6 alkanoyloxy group, an amino group may have a C1-C6 alkyl group as a substituent, a hydroxyl group, a C1-C6 alkoxy phenyl group, a phenoxy group, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted C1-C6 alkoxy group or not substituted by halogen, it can be substituted], a C2-C6 alkenyl group naphthyl, a C1-C6 alkyl benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a group Cl-Cß alkyl substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or non-substituted with halogen, can be replaced]; a C2-C6 alkenyl benzothienyl group; a C2-C6 alkenyl benzothiazolyl group [wherein, in the benzothiazole ring, at least one C1-C6 alkyl group can be substituted]; a C1-C6 alkyl phenyl group [wherein, in the phenyl ring, at least one selected from the following group is substituted: a piperidinyl group (in the piperidine ring, at least one phenoxy group can be substituted [wherein, in the ring phenyl, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted]), a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, is substituted), and a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted by halogen, and an alkoxy group Cl-Cß substi whether or not substituted with halogen, can be substituted)]; a Cl-Cβ-biphenyl alkyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or not substituted with halogen, can be replaced]; a Cl-Cβ benzoyl alkyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or not substituted with halogen, can be replaced]; an amino group wherein at least one selected from the following group can be substituted: a Cl-Cß alkyl group, a Cl-Cβ alkoxycarbonyl group, and a Cl-Cβ phenyl alkyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and an alkoxy Cl group) -Cβ substituted or unsubstituted with halogen, can be substituted), a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted]; a Cl-Cß amino alkyl group wherein at least one selected from the group consisting of a Cl-Cß alkyl group and a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom , a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted) can be substituted; a C2-C6 alkenyl benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group replaced or not substituted with halogen, can be replaced]; a piperidyl group [wherein, in the piperidine ring, at least one C2-C6 alkenyl phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]; a C1-C6 alkyl group substituted with ferrocene; an alkyl Cl-Cβ indolyl group (wherein, in the indole ring, at least one halogen atom can be substituted); a C2-C6 alkynyl group phenyl; a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a C1-C4 alkylenedioxy group, a phenyl group, a C1-Cβ alkoxycarbonyl group, a hydroxyl group, and a phenoxy group (wherein , in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted ), is replaced]; a benzofuryl group [wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom and a Cl-Cß alkyl group can be substituted]; a benzothiazolinyl group [wherein, in the benzothiazoline ring, at least one oxo group can be substituted]; a benzothienyl group [wherein, in the benzothiophene ring, at least one halogen atom can be substituted]; a naphthyl group; a 1, 2, 3, 4-tetrahydroquinolyl group [wherein, in the 1, 2, 3, 4-tetrahydroquinoline ring, at least one selected from the group consisting of an oxo group and a Cl-Cß alkyl group can be substituted ]; a benzoisoxazolyl group; a 2, 3-dihydrobenzofuryl group; a 1,2-dihydroquinolyl group [wherein, in the 1,2-dihydroquinoline ring, at least one oxo group can be substituted]; a 1, 2, 3, 4-tetrahydroquinazolinyl group [wherein, in the 1, 2, 3, 4-tetrahydroquinazoline ring, at least one selected from the group consisting of an oxo group and a Cl-Cß alkyl group can be substituted ]; a benzocycloheptyl group; a Cl-Cβ phenoxy alkyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or not substituted with halogen, can be replaced]; a Cl-Cß alkyl group substituted with benzothienyl [wherein, in the benzothiophene ring, at least one halogen atom can be substituted]; a Cl-Cß alkyl group substituted with naphthyl (wherein, in the naphthalene ring, at least one Cl-Cβ alkoxy group can be substituted); a Cl-Cß alkyl group substituted with pyridyl [wherein, in the pyridine ring, at least one halogen atom can be substituted]; a C 1 -C 3 alkyl group substituted with furyl [wherein, in the furan ring, at least one nitro group can be substituted]; a Cl-Cß alkyl group substituted with thienyl [wherein, in the thiophene ring, at least one halogen atom can be substituted]; a thiazolyl-substituted Cl-Cß alkyl group [wherein, in the thiazole ring, at least one selected from the group consisting of a Cl-Cß alkyl group and a phenyl group (wherein, in the phenyl ring, at least one selected of the group consisting of a halogen atom and a Cl-Cß alkyl group substituted or unsubstituted with halogen can be substituted) can be substituted]; a Cl-Cβ alkyl group substituted with tetrazolyl [wherein, in the tetrazole ring, at least one Cl-Cß alkyl group can be substituted]; a Cl-Cß alkyl group substituted with isoxazolyl [wherein, in the isoxazole ring, at least one Cl-Cß alkyl group can be substituted]; a C 1 -C 2 alkyl group substituted with 1,2,4-oxadiazolyl [wherein, in the 1,2,4-oxadiazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, an alkyl group Cl-Cß can be replaced)]; or a Cl-Cß alkyl group substituted with benzofurazole); (iv) a group represented by the following chemical formula (37): (wherein R 14 represents: a phenylamino group [wherein, at the N-position of the phenylamino group, a Cl-Cß alkyl group can be substituted, and on the phenyl ring of the phenylamino group, at least one substituted Cl-Cβ alkoxy group or not substituted by halogen can be substituted], a piperidyl group [wherein, in the piperidine ring, at least one selected from the group consisting of a phenoxy group (wherein, on the phenyl ring, a substituted C1-Cβ alkoxy group or not substituted by halogen can be substituted) and an amino group (wherein, at the amino group, at least one selected from the group consisting of a Cl-Cß alkyl group and a phenyl group [wherein, on the phenyl ring, less one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted] can be substituted as a substituent ) can be your b) a piperazinyl group [wherein, in the piperazine ring, at least one selected from the following group can be substituted: a C1-C6 alkoxycarbonyl group, a C1-C6 alkyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), a C2 alkenyl group -C6 phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, can be substituted), and a benzoyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C1-C6 alkyl group with halogen, and a C1-C6 alkoxy group sub not substituted by halogen, it can be replaced)]; a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-Cβ alkoxy group with halogen, it can be replaced); a homopiperazinyl group [wherein, in the homopiperazine ring, at least one selected from the group consisting of a C1-Cβ alkoxycarbonyl group and a C1-C3 alkyl phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted) can be substituted]; or a phenoxy group [wherein, on the phenyl ring, at least one selected from the group consisting of a C1-Cß alkoxy group substituted or unsubstituted by halogen and a phenyl group substituted by phenoxy (wherein, on the phenyl ring, at least one C1-Cß alkoxy group substituted or unsubstituted with halogen can be substituted), can be substituted]); (v) a group represented by the following chemical formula (38): (where R13 is the same as the previous one, and a dotted line represents that the link can be a double bond); (vi) a homopiperazinyl group (wherein, in the homopiperazine ring, at least one selected from the following group can be substituted: a Cl-Cβ alkoxycarbonyl group, a Cl-Cβ alkyl phenyl group [wherein, in the phenyl ring, less one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted]; a phenyl group [in where, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cß alkyl group substituted or unsubstituted with halogen, and a C1-Cß alkoxy group substituted or unsubstituted with halogen, can be replaced]; an alkoxycarbonyl Cl-Cβ phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or not substituted with halogen, can be replaced]; a phenylcarbamoyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, it can be replaced]; a C2-C6 alkenyl group phenyl [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be replaced]; and a benzoyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or not substituted with halogen, can be replaced]); (vii) a group represented by the following chemical formula (39): N-R19 -i (39) R20 (wherein R19 represents a C1-C6 alkoxy group, and R20 represents a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or not substituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted]); (viii) a -CHR20R21 group (wherein R20 is the same as the above, and R21 represents an amino group which may have a C1-C6 alkyl group as a substituent); (ix) a 1,2,3,4-tetrahydroisoquinolyl group (wherein, in the 1, 2, 3, 4-tetrahydroisoquinoline ring, at least one amino group can be substituted [where, in the amino group, at least one selected from the group consisting of a C1-C6 alkyl group phenyl (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted) and a Cl-Cß alkyl group can be substituted]); (x) an oxazolyl group (wherein, in the oxazole ring, at least one selected from the following group can be substituted: a phenyl group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted], a Cl-Cß alkyl group, and a piperidyl group [wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]); (xi) an isoindolinyl group (wherein, in the isoindoline ring, at least one selected from the group consisting of a halogen atom, a C1-Cβ alkyl group substituted or unsubstituted with halogen, and a substituted C1-Cβ alkoxy group or not substituted with halogen, can be substituted); (xii) a thiazolyl group (wherein, in the thiazole ring, at least one selected from the following group can be substituted: a Cl-Cβ phenoxy alkyl group [wherein, in the phenyl ring, at least one selected from the group consisting of of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted]; a phenyl group [wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, may be substituted]; -Cβ phenyl [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted or unsubstituted C1-C6 alkoxy group with halogen, it can be your bitumen], a group - (Wi) or NR31R32 [where Wi I are the same as above, and R31 and R32 each identically or differently represent a hydrogen atom, C1-C6 alkyl group, phenyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), or Cl-Cß alkyl phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a substituted Cl-Cβ alkoxy group or not substituted with halogen, can be substituted)]; a piperazinyl group [wherein, in the piperazine ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group) substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]; a piperidyl group [wherein, in the piperidine ring, at least one selected from the group consisting of a phenoxy group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted) and a C1-C6 alkyl group phenyl can be substituted]; and a phenoxy group [wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted C 1 -C 6 alkyl group, and a substituted or unsubstituted C 1 -C 6 alkoxy group substituted with halogen, can be replaced]); (xiii) a C1-C6 alkyl group substituted with hydroxyl group; (xiv) a C 1 -C 6 alkyl oxazolyl group [wherein, in the oxazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted)]; (xv) an isoxazolyl group [wherein, in the isoxazoline ring, at least one phenyl ring can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group Cl -Cβ substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted)]; (xvi) a benzoxazolyl group (wherein, in the benzoxazole ring, at least one halogen atom can be substituted); (xvii) a phenylthio group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a substituted C1-C6 alkoxy group or not substituted with halogen, can be substituted); (xviii) a benzoimidazolyl group [wherein, in the benzoimidazole ring, at least one selected from the group consisting of a halogen atom and a Cl-Cβ phenyl alkyl group (wherein, in the phenyl ring, at least one selected from the group a group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted) can be substituted]; (xiv) a pyrrolidinyl group [wherein, in the pyrrolidine ring, at least one amino group is substituted (wherein, in the amino group, at least one selected from the group consisting of a Cl-Cß alkyl group and a phenyl group) (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can be replaced) can be replaced)]; (xx) a phenylsulfonyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a substituted Cl-Cβ alkoxy group or not substituted with halogen, can be substituted); (xxi) an imidazolyl group [wherein, on the imidazole ring, at least one phenyl group is substituted (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group Cl- Cβ substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted)]; and (xxii) a phenylsulphinyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or not substituted with halogen, can be replaced)]; (s) an imidazolyl group (wherein, in the imidazole ring, at least one selected from the group consisting of a halogen atom and a nitro group can be substituted); (t) an isoindolinyloxy group [wherein, in the isoindoline ring, at least one selected from the following group can be substituted: a Cl-Cβ alkoxycarbonyl group, a Cl-Cβ alkyl phenyl group (wherein, in the phenyl ring, less one selected from the group consisting of a benzofuryl group, a halogen atom, a substituted or unsubstituted Cl-Cß alkyl group with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), a C2-C6 alkenyl group phenyl (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a substituted Cl-Cß alkoxy group or unsubstituted with halogen, can be substituted), a Cl-Cß furyl alkyl group [wherein, in the furan ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group which consists of an atom of halogen, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted)], a Cl-Cβ pyridyl alkyl group [wherein, in the pyridine ring , at least one selected from the group consisting of a furyl group and a phenyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom, a substituted or unsubstituted Cl-Cβ alkyl group) with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), a C 1 -C 6 alkyl benzofuryl group (wherein, in the benzofuran ring, at least one selected from the group consisting of of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted by halogen, and a C1-C6 alkoxy group substituted or unsubstituted by halogen, can be substituted), a C1-C6 alkyl benzothienyl group (wherein, in the benzothiofe ring no, at least one halogen atom can be substituted), a C2-C6 alkenyl benzofuryl group (wherein, in the benzofuran ring, at least one selected from the group consisting of a halogen atom, a substituted Cl-Cß alkyl group or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted), a thiazolyl group [wherein, in the thiazole ring, at least one phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a C1-Cß alkoxy group substituted or unsubstituted with halogen, can be substituted), and a Cl-Cß phenoxy alkyl group (wherein, on the phenyl ring, at least one selected from the group consisting of a halogen atom , a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted)]; (u) a benzothiazolidinyloxy group [wherein, in the benzothiazolidine ring, at least one selected from the group consisting of an oxo group and a C1-C6 alkyl group phenyl (wherein, in the phenyl ring, at least one selected from the group which consists of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a C1-C6 alkoxy group substituted or unsubstituted with halogen, can be substituted), can be substituted]; (v) an indolyloxy group [wherein, in the indole ring, at least one C1-C6 alkyl phenyl group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a C1-C6 alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted)]; (w) a pyrrolidinyl group [wherein, in the pyrrolidine ring, at least one amino group is substituted (wherein, in the amino group, at least one selected from the group consisting of a C1-C6 alkyl group and a phenyl group) (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cß alkyl group substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can be replaced) can be replaced)]; (x) an indolinyl group (wherein, in the indoline ring, at least one halogen atom can be substituted); and (y) an indolinyloxy group [wherein, in the indoline ring, at least one selected from the group consisting of a Cl-Cß phenyl alkyl group (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, a Cl-Cβ alkyl group substituted or unsubstituted with halogen, and a Cl-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted) and an oxo group can be substituted].

2. The 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 1, characterized in that R2 represents a group described in any of (a) to (c), (e) to (h), (j) to (q), and (s) to (y).

3. The compound 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 1, characterized in that R2 represents the group described in (d).

4. The 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 1, characterized in that R2 represents the group described in ( i).

5. The compound 2, 3-dihydro-6-nitroimidazo [2, 1-b] oxazole, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 1, characterized in that R2 represents the group described in (r). H.H.

The 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 1, characterized in that R1 represents a hydrogen atom.

7. The compound 2, 3-dihydro-6-nitroimidazo [2, 1-b] oxazole, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 1, characterized in that R1 represents an alkyl group Cl-Cß.

8. The compound 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 1, characterized in that R1 and - (CH2 ) nR2 can be linked to each other to form a spiro ring together with the carbon atom adjacent thereto, represented by the following formula (30): wherein RRR represents a piperidyl group [wherein, in the piperidine ring, at least one phenoxy group can be substituted (wherein, in the phenyl ring, at least one selected from the group consisting of a halogen atom, an alkyl group C1-C6 substituted or unsubstituted with halogen, and a C1-Cβ alkoxy group substituted or unsubstituted with halogen, can be substituted)].

9. The compound 2,3-dihydro-6-nitroimidazo [2, lb] oxazole, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (i).

10. The compound 2, 3-dihydro-β-nitroimidazo [2, lb] oxazole, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (ii). eleven .

The 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (iii).

12. The 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (iv).

13. The compound 2, 3-dihydro-6-nitroimidazo [2, 1-b] oxazole, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (v).

14. The 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (vi).

15. The 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (vii).

16. The compound 2, 3-dihydro-6-nitroimidazo [2, 1-b] oxazole, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (viii).

17. The compound 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (ix).

18. The 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (x).

19. The compound 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (xi).

20. The 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (xii).

21. The compound 2, 3-dihydro-6-nitroimidazo [2, 1-b] oxazole, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (xiii).

22. The 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmtically acceptable salt thereof according to claim 6, characterized in that R3 represents the group described in (xiv).

23. The 2,3-dihydro-β-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmtically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (xv).

24. The compound 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole, an optically active form thereof, or a pharmtically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (xvi).

25. The 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmtically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (xvii).

26. The compound 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole, an optically active form thereof, or a pharmtically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (xviii).

27. The 2,3-dihydro-β-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmtically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (xix).

28. The 2,3-dihydro-β-nitroimidazo [2, 1-b] oxazole compound, an optically active form thereof, or a pharmtically acceptable salt thereof according to claim 6 or 7, characterized in that R3 represents the group described in (xx).

29. The compound 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole, an optically active form thereof, or a pharmtically acceptable salt thereof according to claim 6, characterized in that R represents the group described in (xxi).

30. The compound 2, 3-dihydro-6-nitroimidazo [2, 1-b] oxazole, an optically active form thereof, or a pharmtically acceptable salt thereof according to claim ß or 7, characterized in that R represents the group described in (xxii).

31. The compound 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole or a pharmtically acceptable salt thereof according to claim 1, characterized in that it is selected from the group consisting of: 2-methyl-6 -nitro-2-. { 4- [4- (4- trifluoromethylbenzyloxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-β-nitro-2-. { 4- [4- (4-trifluoromethylbenzyloxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethylbenzyloxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2-. { 4- [4- (4-chlorophenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-β-nitro-2-. { 4- [4- (4-chlorophenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-β-nitro-2-. { 4- [4- (4-chlorophenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethyl-cinnamyl) piperazinyl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethylancinamyl) piperazin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-β-nitro-2-. { 4- [4- (4-trifluoromethylancinamyl) piperazin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethoxycinnamyl) piperazinyl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-β-nitro-2-. { 4- [4- (4-trifluoromethoxycinnamyl) piperazin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethoxycinnamyl) piperazin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethylphenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethylphenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethylphenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroiraidazo [2, 1-b] oxazole, 6-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyloxy) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -6-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyloxy) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -β-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyloxy) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 6-nitro-2-. { 4- [4- (4-trifluoromethoxyphenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -6-nitro-2-. { 4- [4- (4-trifluoromethoxyphenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -β-nitro-2-. { 4- [4- (4-trifluoromethoxyphenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 6-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -6-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -6-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [4- (4-trifluoromethoxybenzyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2- [4-. { 4- [4- (4-trifluoromethylphenyl) iperazin-1-yl] piperidin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2- [4-. { 4- [4- (4-trifluoromethylphenyl) piperazin-1-yl] piperidin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2- [4-. { 4- [4- (4-trifluoromethylphenyl) piperazin-1-yl] piperidin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2- [4-. { 4- [4- (4-trifluoromethoxyphenoxy) benzyl] piperazin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-β-nitro-2- [4-. { 4- [4- (4-trifluoromethoxyphenoxy) benzyl] piperazin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2- [4-. { 4- [4- (4-trifluoromethoxyphenoxy) benzyl] piperazin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, 6-nitro-2- [4-. { 4- [3- (4-trifluoromethoxyphenyl) propyl] iperidin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, (R) -6-nitro-2- [4-. { 4- [3- (4-trifluoromethoxyphenyl) propyl] piperidin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, (S) -6-nitre-2- [4-. { 4- [3- (4-trifluoromethoxyphenyl) propyl] piperidin-1-yl} phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-β-nitro-2-. { 4- [2- (4-trifluoromethoxyphenyl) oxazol-4-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2-. { 4- [2- (4-trifluoromethoxyphenyl) oxazol-4-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [2- (4-trifluoromethoxyphenyl) oxazol-4-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 6-nitro-2-. { 4- [4- (4-chlorophenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -6-nitro-2-. { 4- [4- (4-chlorophenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -6-nitro-2-. { 4- [4- (4-chlorophenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2-. { 4- [4- (5-trifluoromethylbenzofuran-2-yl) methylpiperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2-. { 4- [4- (5-trifluoromethylbenzofuran-2-yl) methylpiperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [4- (5-trifluoromethylbenzofuran-2-yl) methylpiperidin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2-. { 4- [2- (4-chlorophenyl) oxazol-4-yl] phenoxy ethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2-. { 4- [2- (4-chlorophenyl) oxazol-4-yl] phenoxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-6-nitro-2-. { 4- [2- (4-chlorophenyl) oxazol-4-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 6-nitro-2-. { 4- [4- (4-trif luoromethyl-phenoxymethyl) piperidin-1-yl] phenoxymethyl} -2, 3-dihydroxy? Idazo [2, 1-b] oxazole, (R) -6-nitro-2-. { 4- [4- (4-trif luoromethyl-phenoxymethyl) piperidin-1-yl] -f-enoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -6-nitro-2-. { 4- [4- (4-trif luoromethyl-phenoxymethyl) -peridin-1-yl] -f-enoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-β-nitro-2-. { 4- [4- (4-Bromokinamyl) piperazin-lyl] f-enoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2-. { 4- [4- (4-Bromokinamyl) piperazinyl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, (S) -2-methyl-β-nitro-2-. { 4- [4- (4-Bromokinamyl) piperazin-1-yl] phenoxymethyl} -2, 3-dihydroimidazo [2, 1-b] oxazole, 2-methyl-6-nitro-2- [2- (4-trif luoromethoxyphenyl) -1, 2, 3, 4-tetrahydroisoquinolin-6-yloxymethyl] -2, 3-dihydroimidazo [2, 1-b] oxazole, (R) -2-methyl-6-nitro-2- [2- (4-trif luoromethoxy-enyl) -1, 2, 3, 4-tetrahydroisoquinolin- 6-yloxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole, and (S) -2-methyl-6-nitro-2- [2- (4-trif luoromethoxy-enyl) -1, 2, 3 , 4-tetrahydroisoquinolin-6-yloxymethyl] -2,3-dihydroimidazo [2, 1-b] oxazole.

32 An antitubercular agent, characterized in that it comprises 2,3-dihydro-6-nitroimidazo [2, 1-b] oxazole, an optically active form thereof, or a pharmaceutically acceptable salt thereof according to claim 1.

33. A method for producing a compound represented by the general formula (1) (wherein R1, R2, and n have the same definitions as described in claim 1), characterized in that it comprises: a reaction of a 4-nitroimidazole compound represented by the following general formula (2): (wherein Xi represents a halogen atom or a nitro group), with an epoxy compound represented by the following general formula (3a): (wherein R1, R2 and n have the same definitions as described in claim 1), to obtain a compound represented by the following general formula (4a): (wherein R1, R2 and n have the same definitions as described in claim 1, and X1 represents a halogen atom or a nitro group); and a rear ring closure of the obtained compound represented by the above general formula (4a). 3. 4 .

A method for producing a compound represented by the following general formula (lw): (wherein R 1 * represents a hydrogen atom, or a Cl-Cß alkyl group, R ^ represents a group described in any of (a) to (y) in accordance with claim 1, and n represents an integer between 0 and 6 ), characterized in that it comprises: a reaction of a compound represented by the following general formula (3b): (wherein R1A is the same as described above, and X1 represents a halogen atom or nitro group), with a compound R2AH (5) or a salt thereof (wherein R2A represents a group described in one of any of ( a) to (y) according to claim 1), to obtain a compound represented by the following general formula (4c): (wherein R1 has the same definition as described in claim 1, R2A represents a group described in one of any of (a) through (and) as defined in claim 1, and X1 represents a halogen atom or a nitro group); and a rear ring closure of the obtained compound represented by the above general formula (4c).

35. A method for producing a compound represented by the following general formula (lw): (wherein R1A, R2a, and n have the same definitions as described in claim 34), characterized in that it comprises: a reaction of a compound represented by the following general formula (6): (wherein R and n have the same definitions as described in claim 34, and R 15 represents an alkylsulfonyl Cl-Cβ group or a benzenesulfonyl group in which a Cl-Cß alkyl group can be substituted), with a compound R2AH (5) or a salt thereof (wherein R2A represents a group described in one of any of (a) to (y) in accordance with claim 1).