MXPA06001974A - Novel sulfenamide oxides. - Google Patents
Novel sulfenamide oxides.Info
- Publication number
- MXPA06001974A MXPA06001974A MXPA06001974A MXPA06001974A MXPA06001974A MX PA06001974 A MXPA06001974 A MX PA06001974A MX PA06001974 A MXPA06001974 A MX PA06001974A MX PA06001974 A MXPA06001974 A MX PA06001974A MX PA06001974 A MXPA06001974 A MX PA06001974A
- Authority
- MX
- Mexico
- Prior art keywords
- sulfenamide
- disclosed
- compounds
- oxides
- general formula
- Prior art date
Links
- QAZLUNIWYYOJPC-UHFFFAOYSA-M sulfenamide Chemical compound [Cl-].COC1=C(C)C=[N+]2C3=NC4=CC=C(OC)C=C4N3SCC2=C1C QAZLUNIWYYOJPC-UHFFFAOYSA-M 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Sulfenamide oxide compounds of general formula (I) are disclosed wherein A, R1, R2, X1, X1aCO, X2, X2aCO, X3, X3aCO, X4, X4aCO, X5 and X5aCO define a variety of variables and wherein q is 0 or 1 and p is 1 or 2. The compounds disclosed in the examples are galactofuranosyl and glucofuranosyl sulfenamide oxide compounds wherein the variable A is oxygen. Methods of synthesis of compounds of general formula (I), pharmaceutical compositions containing them and methods of using them to treat patients suffering a microbial infection are also disclosed.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2003904500A AU2003904500A0 (en) | 2003-08-21 | Novel compounds II | |
| AU2003904501A AU2003904501A0 (en) | 2003-08-21 | Novel compounds III | |
| PCT/AU2004/001110 WO2005019236A1 (en) | 2003-08-21 | 2004-08-20 | Novel sulfenamide oxides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA06001974A true MXPA06001974A (en) | 2006-05-31 |
Family
ID=34218927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA06001974A MXPA06001974A (en) | 2003-08-21 | 2004-08-20 | Novel sulfenamide oxides. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1664071A1 (en) |
| JP (1) | JP2007502778A (en) |
| BR (1) | BRPI0413682A (en) |
| CA (1) | CA2535800A1 (en) |
| MX (1) | MXPA06001974A (en) |
| RU (1) | RU2006108577A (en) |
| WO (1) | WO2005019236A1 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7601716B2 (en) | 2006-05-01 | 2009-10-13 | Cephalon, Inc. | Pyridopyrazines and derivatives thereof as ALK and c-Met inhibitors |
| EP2370451B1 (en) | 2008-12-02 | 2016-11-16 | Wave Life Sciences Japan, Inc. | Method for the synthesis of phosphorus atom modified nucleic acids |
| KR101885383B1 (en) | 2009-07-06 | 2018-08-03 | 웨이브 라이프 사이언시스 리미티드 | Novel nucleic acid prodrugs and methods of use thereof |
| US10428019B2 (en) | 2010-09-24 | 2019-10-01 | Wave Life Sciences Ltd. | Chiral auxiliaries |
| EP2734208B1 (en) | 2011-07-19 | 2017-03-01 | Wave Life Sciences Ltd. | Methods for the synthesis of functionalized nucleic acids |
| PL2872485T3 (en) | 2012-07-13 | 2021-05-31 | Wave Life Sciences Ltd. | Asymmetric auxiliary group |
| EP4137572A1 (en) | 2014-01-16 | 2023-02-22 | Wave Life Sciences Ltd. | Chiral design |
| CA3033867A1 (en) | 2016-08-17 | 2018-02-22 | Solstice Biologics, Ltd. | Polynucleotide constructs |
| EP3645546A4 (en) | 2017-06-30 | 2021-12-01 | Solstice Biologics, Ltd. | CHIRAL PHOSPHORAMIDITE AIDS AND METHOD FOR THEIR USE |
| UY38979A (en) | 2019-12-06 | 2021-07-30 | Vertex Pharma | TETRAHYDROFURANS REPLACED AS SODIUM CHANNEL MODULATORS |
| BR112022024071A2 (en) | 2020-05-27 | 2022-12-20 | Axial Therapeutics Inc | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND THEIR USES |
| TW202313593A (en) | 2021-06-04 | 2023-04-01 | 美商維泰克斯製藥公司 | N-(hydroxyalkyl (hetero)aryl) tetrahydrofuran carboxamides as modulators of sodium channels |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1646513A (en) * | 2002-02-22 | 2005-07-27 | 格里菲斯大学 | An antimicrobial agent |
-
2004
- 2004-08-20 RU RU2006108577/04A patent/RU2006108577A/en not_active Application Discontinuation
- 2004-08-20 MX MXPA06001974A patent/MXPA06001974A/en not_active Application Discontinuation
- 2004-08-20 CA CA002535800A patent/CA2535800A1/en not_active Abandoned
- 2004-08-20 JP JP2006523486A patent/JP2007502778A/en active Pending
- 2004-08-20 EP EP04761147A patent/EP1664071A1/en not_active Withdrawn
- 2004-08-20 WO PCT/AU2004/001110 patent/WO2005019236A1/en not_active Ceased
- 2004-08-20 BR BRPI0413682-9A patent/BRPI0413682A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2535800A1 (en) | 2005-03-03 |
| RU2006108577A (en) | 2007-09-27 |
| WO2005019236A1 (en) | 2005-03-03 |
| EP1664071A1 (en) | 2006-06-07 |
| JP2007502778A (en) | 2007-02-15 |
| BRPI0413682A (en) | 2006-10-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |