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MXPA06000441A - Derivado de 2-acilaminotiazole o sal del mismo. - Google Patents

Derivado de 2-acilaminotiazole o sal del mismo.

Info

Publication number
MXPA06000441A
MXPA06000441A MXPA06000441A MXPA06000441A MXPA06000441A MX PA06000441 A MXPA06000441 A MX PA06000441A MX PA06000441 A MXPA06000441 A MX PA06000441A MX PA06000441 A MXPA06000441 A MX PA06000441A MX PA06000441 A MXPA06000441 A MX PA06000441A
Authority
MX
Mexico
Prior art keywords
salt
acylaminothiazole derivative
acylaminothiazole
derivative
megakaryoblast
Prior art date
Application number
MXPA06000441A
Other languages
English (en)
Inventor
Ken-Ichi Suzuki
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of MXPA06000441A publication Critical patent/MXPA06000441A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Se proporciona un derivado de 2-acilaminotiazole, el cual tiene actividad en incrementar plaquetas con base en excelentes efectos de proliferacion de celulas c-mpl-Ba/F3 de humano y en promover la formacion de colonias de megacarioblastos y que es util para tratar trombocitopenia.
MXPA06000441A 2003-07-17 2004-07-15 Derivado de 2-acilaminotiazole o sal del mismo. MXPA06000441A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003275718 2003-07-17
PCT/JP2004/010440 WO2005007651A1 (ja) 2003-07-17 2004-07-15 ２-アシルアミノチアゾール誘導体又はその塩

Publications (1)

Publication Number Publication Date
MXPA06000441A true MXPA06000441A (es) 2006-04-05

Family

ID=34074565

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA06000441A MXPA06000441A (es) 2003-07-17 2004-07-15 Derivado de 2-acilaminotiazole o sal del mismo.

Country Status (8)

Country Link
US (1) US7361658B2 (es)
EP (1) EP1647553A4 (es)
JP (1) JP4324791B2 (es)
KR (1) KR100907317B1 (es)
CN (1) CN1835948B (es)
CA (1) CA2529686C (es)
MX (1) MXPA06000441A (es)
WO (1) WO2005007651A1 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1466912T3 (da) 2002-01-18 2013-07-01 Astellas Pharma Inc 2-acylaminothiazolderivat eller salt deraf
JP4774995B2 (ja) * 2005-01-12 2011-09-21 アステラス製薬株式会社 アシルアミノチアゾール誘導体を有効成分とする医薬組成物
WO2007046867A2 (en) * 2005-05-19 2007-04-26 Xenon Pharmaceuticals Inc. Piperidine derivatives and their uses as therapeutic agents
WO2007036769A1 (en) * 2005-07-05 2007-04-05 Pfizer Products Inc. Aminothiazole derivatives as agonists of the thrombopoietin receptor
WO2007004038A1 (en) * 2005-07-05 2007-01-11 Pfizer Products Inc. Aminothiazole derivatives as agonists of the thrombopoietin receptor
US20070203153A1 (en) * 2005-11-08 2007-08-30 Astellas Pharma Inc. Compositions and methods for treating thrombocytopenia
JP2010500361A (ja) * 2006-08-08 2010-01-07 アカークス，インコーポレーテッド ヒトの血小板レベルを増加させるための組成物および方法
RU2476429C2 (ru) 2007-07-31 2013-02-27 Сионоги Энд Ко., Лтд. Фармацевтическая композиция, содержащая оптически активное соединение, обладающее активностью агониста рецептора тромбопоэтина, и промежуточное соединение для этого
RU2490257C2 (ru) * 2008-05-30 2013-08-20 Такеда Фармасьютикал Компани Лимитед Гетероциклическое соединение
US20110166112A1 (en) * 2009-08-14 2011-07-07 Eisai, Inc. Method for stimulating platelet production
CN104039761A (zh) 2011-11-14 2014-09-10 利亘制药公司 与粒细胞集落刺激因子受体相关的方法和组合物
BR112014012056B1 (pt) * 2011-11-18 2021-12-14 Heptares Therapeutics Limited Compostos agonistas do receptor m1 muscarínico, composição farmacêutica compreendendo os ditos compostos e uso dos mesmos para tratar um distúrbio cognitivo ou psicótico ou para tratamento ou diminuição da severidade da dor aguda, crônica, neuropática ou inflamatória
TWI647227B (zh) * 2013-02-28 2019-01-11 日商安斯泰來製藥股份有限公司 ２－醯胺噻唑衍生物或其鹽
WO2014150252A1 (en) 2013-03-15 2014-09-25 Ligand Pharmaceuticals Incorporated Methods of treatment associated with the granulocyte colony-stimulating factor receptor
GB201404922D0 (en) 2014-03-19 2014-04-30 Heptares Therapeutics Ltd Pharmaceutical compounds
HUE043496T2 (hu) * 2014-06-06 2019-08-28 Astellas Pharma Inc 2-aminotiazol származék hólyag/húgyúti betegségek megelõzésében vagy kezelésében történõ alkalmazásra
CN106573928B (zh) * 2014-08-26 2020-04-14 安斯泰来制药株式会社 2-氨基噻唑衍生物或其盐
GB201513743D0 (en) 2015-08-03 2015-09-16 Heptares Therapeutics Ltd Muscarinic agonists
GB201519352D0 (en) 2015-11-02 2015-12-16 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201617454D0 (en) 2016-10-14 2016-11-30 Heptares Therapeutics Limited Pharmaceutical compounds
GB201810239D0 (en) 2018-06-22 2018-08-08 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201819961D0 (en) 2018-12-07 2019-01-23 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201819960D0 (en) 2018-12-07 2019-01-23 Heptares Therapeutics Ltd Pharmaceutical compounds
GB202020191D0 (en) 2020-12-18 2021-02-03 Heptares Therapeutics Ltd Pharmaceutical compounds
IL298475A (en) * 2020-06-09 2023-01-01 Anima Biotech Inc Collagen-1 translation inhibitors and methods of their use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256675A (en) 1989-08-07 1993-10-26 Fujisawa Pharmaceutical Co., Ltd. Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same
TW205041B (es) * 1989-08-07 1993-05-01 Fujisawa Pharmaceutical Co
FR2677356B1 (fr) * 1991-06-05 1995-03-17 Sanofi Sa Derives heterocycliques d'acylamino-2 thiazoles-5 substitues, leur preparation et compositions pharmaceutiques en contenant.
AU6023300A (en) * 1999-07-26 2001-02-13 Shionogi & Co., Ltd. Drug compositions exhibiting thrombopoietin agonism
TWI284639B (en) 2000-01-24 2007-08-01 Shionogi & Co A compound having thrombopoietin receptor agonistic effect
JPWO2002062775A1 (ja) * 2001-02-02 2004-06-10 山之内製薬株式会社 ２−アシルアミノチアゾール誘導体又はその塩
DK1466912T3 (da) * 2002-01-18 2013-07-01 Astellas Pharma Inc 2-acylaminothiazolderivat eller salt deraf

Also Published As

Publication number Publication date
JP2005047905A (ja) 2005-02-24
CN1835948A (zh) 2006-09-20
KR20060039908A (ko) 2006-05-09
WO2005007651A1 (ja) 2005-01-27
US20060194844A1 (en) 2006-08-31
CA2529686A1 (en) 2005-01-27
EP1647553A1 (en) 2006-04-19
CA2529686C (en) 2010-06-15
CN1835948B (zh) 2010-05-26
EP1647553A4 (en) 2008-12-31
KR100907317B1 (ko) 2009-07-13
US7361658B2 (en) 2008-04-22
JP4324791B2 (ja) 2009-09-02

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