MXPA05014089A - Composiciones farmaceuticas que comprenden sustancias inhibidoras de la recaptura de noradrenalina, dopamina y serotonina, combinadas con un aminoacido para el tratamiento de la obesidad y sobrepeso. - Google Patents
Composiciones farmaceuticas que comprenden sustancias inhibidoras de la recaptura de noradrenalina, dopamina y serotonina, combinadas con un aminoacido para el tratamiento de la obesidad y sobrepeso.Info
- Publication number
- MXPA05014089A MXPA05014089A MXPA05014089A MXPA05014089A MXPA05014089A MX PA05014089 A MXPA05014089 A MX PA05014089A MX PA05014089 A MXPA05014089 A MX PA05014089A MX PA05014089 A MXPA05014089 A MX PA05014089A MX PA05014089 A MXPA05014089 A MX PA05014089A
- Authority
- MX
- Mexico
- Prior art keywords
- noradrenaline
- reuptake
- overweight
- serotonin
- dopamine
- Prior art date
Links
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 title abstract 6
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 title abstract 6
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 title abstract 3
- 208000008589 Obesity Diseases 0.000 title abstract 3
- 206010033307 Overweight Diseases 0.000 title abstract 3
- 150000001413 amino acids Chemical class 0.000 title abstract 3
- 229960003638 dopamine Drugs 0.000 title abstract 3
- 229960002748 norepinephrine Drugs 0.000 title abstract 3
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 title abstract 3
- 235000020824 obesity Nutrition 0.000 title abstract 3
- 229940076279 serotonin Drugs 0.000 title abstract 3
- 239000000126 substance Substances 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- UNAANXDKBXWMLN-UHFFFAOYSA-N sibutramine Chemical compound C=1C=C(Cl)C=CC=1C1(C(N(C)C)CC(C)C)CCC1 UNAANXDKBXWMLN-UHFFFAOYSA-N 0.000 abstract 1
- 229960004425 sibutramine Drugs 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Child & Adolescent Psychology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invencion esta relacionada con la industria farmaceutica en general y con la industria farmaceutica productora de medicamentos para el control de la obesidad y el sobrepeso. Mas especificamente se trata de una composicion formada por una sustancia inhibidora de la recaptura de Noradrenalina, Dopamina y Serotonina y un Aminoacido. La composicion se caracteriza en que dicha combinacion o asociacion consiste de una sustancia seleccionada inhibidor de la recaptura de Noradrenalina, Dopamina y Serotonina conocida como Sibutramina y un Aminoacido conocido L-Carnitina; los cuales producen un producto con efecto sinergico para el tratamiento de la obesidad y el sobrepeso, con menores efectos secundarios.
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MXPA05014089A MXPA05014089A (es) | 2005-12-20 | 2005-12-20 | Composiciones farmaceuticas que comprenden sustancias inhibidoras de la recaptura de noradrenalina, dopamina y serotonina, combinadas con un aminoacido para el tratamiento de la obesidad y sobrepeso. |
| EP06783800A EP1964555A1 (en) | 2005-12-20 | 2006-07-12 | Pharmaceutical compositions containing substances that inhibit the reuptake of noradrenaline, dopamine and serotonin, which are combined with an amino acid for the treatment of obesity and overweight |
| PCT/MX2006/000070 WO2007073133A1 (es) | 2005-12-20 | 2006-07-12 | Composiciones farmaceuticas que comprenden sustancias inhibidoras de la recaptura de noradrenalina, dopamina y serotonina, combinadas con un aminoácido para el tratamiento de la obesidad y sobrepeso |
| BRPI0620104-0A BRPI0620104A2 (pt) | 2005-12-20 | 2006-07-12 | composições farmacêuticas que contém as substáncias que inibem a reabsorção da noradrenalina, dopamina e da serotonina, que são combinados com um aminoácido para o tratamento da obesidade e do excesso de peso |
| EC2008008568A ECSP088568A (es) | 2005-12-20 | 2008-06-20 | Composiciones farmacéuticas que comprenden sustancias inhibidoras de la recaptura de noradrenalina, dopamina y serotonina, combinadas con un aminoácido para el tratamiento de la obesidad y sobrepeso |
| CR10109A CR10109A (es) | 2005-12-20 | 2008-06-23 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MXPA05014089A MXPA05014089A (es) | 2005-12-20 | 2005-12-20 | Composiciones farmaceuticas que comprenden sustancias inhibidoras de la recaptura de noradrenalina, dopamina y serotonina, combinadas con un aminoacido para el tratamiento de la obesidad y sobrepeso. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA05014089A true MXPA05014089A (es) | 2007-06-20 |
Family
ID=38188838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA05014089A MXPA05014089A (es) | 2005-12-20 | 2005-12-20 | Composiciones farmaceuticas que comprenden sustancias inhibidoras de la recaptura de noradrenalina, dopamina y serotonina, combinadas con un aminoacido para el tratamiento de la obesidad y sobrepeso. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1964555A1 (es) |
| BR (1) | BRPI0620104A2 (es) |
| CR (1) | CR10109A (es) |
| EC (1) | ECSP088568A (es) |
| MX (1) | MXPA05014089A (es) |
| WO (1) | WO2007073133A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101555214B (zh) | 2008-04-08 | 2012-07-11 | 北京嘉事联博医药科技有限公司 | 苯基环丁基酰胺衍生物及其光学异构体、制备方法和用途 |
| KR101007927B1 (ko) | 2008-12-24 | 2011-01-14 | 주식회사 셀트리온제약 | 시부트라민-ｌ-카르니틴 다이술폰산염, 이의 제조방법 및 이를 포함하는 약제학적 조성물 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6426096B1 (en) * | 1997-12-10 | 2002-07-30 | Paolina Galvao | Anorexigenic composition |
| IT1307278B1 (it) * | 1999-11-18 | 2001-10-30 | Sigma Tau Healthscience Spa | Composizione per la prevenzione e/o il trattamento di disturbi dovutiad un alterato metabolismo dei lipidi, che comprende propionil |
-
2005
- 2005-12-20 MX MXPA05014089A patent/MXPA05014089A/es active IP Right Grant
-
2006
- 2006-07-12 EP EP06783800A patent/EP1964555A1/en not_active Withdrawn
- 2006-07-12 WO PCT/MX2006/000070 patent/WO2007073133A1/es not_active Ceased
- 2006-07-12 BR BRPI0620104-0A patent/BRPI0620104A2/pt not_active IP Right Cessation
-
2008
- 2008-06-20 EC EC2008008568A patent/ECSP088568A/es unknown
- 2008-06-23 CR CR10109A patent/CR10109A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ECSP088568A (es) | 2008-07-30 |
| EP1964555A1 (en) | 2008-09-03 |
| CR10109A (es) | 2008-08-06 |
| WO2007073133A1 (es) | 2007-06-28 |
| BRPI0620104A2 (pt) | 2011-11-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or assignment | ||
| FG | Grant or registration | ||
| GD | Licence granted | ||
| GB | Transfer or assignment | ||
| GD | Licence granted |