MXPA05003844A - Compuestos con base de glucosa con afinidad para p-selectina. - Google Patents
Compuestos con base de glucosa con afinidad para p-selectina.Info
- Publication number
- MXPA05003844A MXPA05003844A MXPA05003844A MXPA05003844A MXPA05003844A MX PA05003844 A MXPA05003844 A MX PA05003844A MX PA05003844 A MXPA05003844 A MX PA05003844A MX PA05003844 A MXPA05003844 A MX PA05003844A MX PA05003844 A MXPA05003844 A MX PA05003844A
- Authority
- MX
- Mexico
- Prior art keywords
- selectin
- glucose
- based compounds
- affinity
- relates
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title abstract 3
- 239000008103 glucose Substances 0.000 title abstract 3
- 102000008212 P-Selectin Human genes 0.000 abstract 3
- 108010035766 P-Selectin Proteins 0.000 abstract 3
- 239000000562 conjugate Substances 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Physical Education & Sports Medicine (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invencion se relaciona con ciertos compuestos con base de glucosa que tienen una afinidad para P-selectina. Ademas, la invencion se relaciona con el uso de estos compuestos con base de glucosa para la preparacion de composiciones farmaceuticas para el tratamiento de trastornos asociados con P-selectina, con conjugados, portadores farmaceuticos y sistemas para suministro de farmacos que comprenden los compuestos, y con un metodo para determinar si un compuesto es capaz o no de unirse a P-selectina.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02079232 | 2002-10-11 | ||
| PCT/EP2003/011457 WO2004033473A1 (en) | 2002-10-11 | 2003-10-13 | Glucose-based compounds with affinity to p-selectin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA05003844A true MXPA05003844A (es) | 2005-06-22 |
Family
ID=32088032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA05003844A MXPA05003844A (es) | 2002-10-11 | 2003-10-13 | Compuestos con base de glucosa con afinidad para p-selectina. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7304039B2 (es) |
| EP (1) | EP1549658B1 (es) |
| JP (1) | JP4603888B2 (es) |
| AT (1) | ATE444301T1 (es) |
| AU (1) | AU2003278090A1 (es) |
| BR (1) | BR0315231A (es) |
| CA (1) | CA2501842C (es) |
| DE (1) | DE60329511D1 (es) |
| ES (1) | ES2334220T3 (es) |
| MX (1) | MXPA05003844A (es) |
| WO (1) | WO2004033473A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011127136A1 (en) * | 2010-04-06 | 2011-10-13 | University Of Chicago | Composition and methods related to modification of 5-hydroxymethylcytosine (5-hmc) |
| WO2012019021A1 (en) * | 2010-08-04 | 2012-02-09 | Wisconsin Alumni Research Foundation | Methods and pharmaceutical compositions for treating adverse or deleterious sequellae of traumatic brain injury |
| CN117222433A (zh) * | 2020-10-01 | 2023-12-12 | 密西西比州立大学 | 与磷酸己糖缀合的药物及其制备和使用方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994005314A1 (en) * | 1992-09-08 | 1994-03-17 | Centocor, Inc. | Peptide inhibitors of leukocyte adhesion |
| PL176272B1 (pl) * | 1993-05-14 | 1999-05-31 | Cytel Corp | Analogi sialilowe Le jako inhibitory adhezji komórkowej |
| WO1996009309A1 (en) | 1994-09-20 | 1996-03-28 | Pharmacia & Upjohn Company | The oligosaccharide structure of a ligand for e and p selectin |
| AR008283A1 (es) | 1996-08-08 | 1999-12-29 | Maes Louis | Oligosacaridos modificados, el metodo de preparacion, composiciones farmaceuticas, procedimientos para producir los medicamentos y usos para lamanufactura de un medicamento. |
| AU4700497A (en) * | 1996-08-26 | 1998-03-19 | Novartis Ag | Organic compounds |
| US5830871A (en) | 1996-10-28 | 1998-11-03 | The Scripps Research Institute | Inhibitors of E-, P- and L-selectin binding |
| AU1144799A (en) * | 1997-08-26 | 1999-03-16 | Novartis Ag | Organic compounds |
| EP1288222A1 (en) | 2001-09-03 | 2003-03-05 | Yamanouchi Europe B.V. | Peptidic compounds selectively binding to P-selectin |
| JP4563806B2 (ja) | 2002-08-09 | 2010-10-13 | アステラス ファルマ ユーロープ ベスローテン フェンノートシャップ | Ｐ−セレクチンに対する結合性化合物 |
-
2003
- 2003-10-13 AT AT03769400T patent/ATE444301T1/de not_active IP Right Cessation
- 2003-10-13 AU AU2003278090A patent/AU2003278090A1/en not_active Abandoned
- 2003-10-13 CA CA2501842A patent/CA2501842C/en not_active Expired - Fee Related
- 2003-10-13 EP EP03769400A patent/EP1549658B1/en not_active Expired - Lifetime
- 2003-10-13 BR BR0315231-6A patent/BR0315231A/pt not_active IP Right Cessation
- 2003-10-13 WO PCT/EP2003/011457 patent/WO2004033473A1/en not_active Ceased
- 2003-10-13 MX MXPA05003844A patent/MXPA05003844A/es unknown
- 2003-10-13 DE DE60329511T patent/DE60329511D1/de not_active Expired - Lifetime
- 2003-10-13 US US10/530,601 patent/US7304039B2/en not_active Expired - Fee Related
- 2003-10-13 JP JP2004542495A patent/JP4603888B2/ja not_active Expired - Fee Related
- 2003-10-13 ES ES03769400T patent/ES2334220T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006503876A (ja) | 2006-02-02 |
| ES2334220T3 (es) | 2010-03-08 |
| ATE444301T1 (de) | 2009-10-15 |
| US20050261207A1 (en) | 2005-11-24 |
| CA2501842C (en) | 2012-07-17 |
| EP1549658A1 (en) | 2005-07-06 |
| DE60329511D1 (de) | 2009-11-12 |
| AU2003278090A1 (en) | 2004-05-04 |
| JP4603888B2 (ja) | 2010-12-22 |
| CA2501842A1 (en) | 2004-04-22 |
| WO2004033473A1 (en) | 2004-04-22 |
| US7304039B2 (en) | 2007-12-04 |
| BR0315231A (pt) | 2005-08-23 |
| EP1549658B1 (en) | 2009-09-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MXPA03007837A (es) | Composiciones para suministrar bisfosfonatos. | |
| UA96449C2 (en) | Stable laquinimod preparations | |
| MXPA04004842A (es) | Inhibidores de 11-(-hidroxiesteroide deshidrogenasa de tipo 1. | |
| MXPA04004837A (es) | Inhibidores de 11-??-hidroxiesteroide deshidrogenasa de tipo 1. | |
| PL370111A1 (en) | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | |
| ATE339406T1 (de) | Chinazoline verbindungen als heilmittel | |
| MXPA04004567A (es) | Compuestos y composiciones de fenoxi amina para adminstrar agentes activos. | |
| CY1111470T1 (el) | Νεες φαρμακευτικες συνθεσεις που περιεχουν φλιβανσερινη πολυμορφη α | |
| MY145074A (en) | Thiazolidin-4-one derivatives | |
| MXPA03007857A (es) | Compuestos y composiciones para entregar agentes activos. | |
| TW200621737A (en) | 2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof | |
| UA96302C2 (en) | Solid dosage form comprising 2-ethoxy-1-{[2'-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl]methyl}-1h-benzimidazole-7-carboxylic acid | |
| WO2001003649A3 (en) | Compositions and methods for the treatment of parkinson's disease | |
| IL164974A0 (en) | Novel compounds and their use | |
| NZ547587A (en) | Pharmaceutical compositions and methods for insulin treatment | |
| IL157226A0 (en) | Composition and method for potentiating drugs | |
| WO2005117895A8 (en) | Compositions comprising meloxicam | |
| WO2004087880A3 (en) | Compounds and their use to treat diabetes and related disorders | |
| MXPA03005980A (es) | Composiciones para administracion nasal de insulina. | |
| WO2008008882A3 (en) | Glucocorticoid receptor modulator and methods of use | |
| WO2003035080A3 (en) | A process for the preparation of pharmaceutical compositions for topical delivery of cyclooxygenase-2 enzyme inhibitors | |
| WO2004073615A8 (en) | Deazaflavin compounds and methods of use thereof | |
| WO2004006830A3 (en) | Use of ccn protein family members for the treatment of disorder associated to an altered calcium and/or sodium flux | |
| MXPA05003844A (es) | Compuestos con base de glucosa con afinidad para p-selectina. | |
| PL1699468T3 (pl) | Środek farmaceutyczny zawierający kompleks cynk-hialuronian do leczenia stwardnienia rozsianego |