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MXPA04006395A - Una formulacion farmaceutica liquida que comprende nicotina para la administracion en la cavidad oral. - Google Patents

Una formulacion farmaceutica liquida que comprende nicotina para la administracion en la cavidad oral.

Info

Publication number
MXPA04006395A
MXPA04006395A MXPA04006395A MXPA04006395A MXPA04006395A MX PA04006395 A MXPA04006395 A MX PA04006395A MX PA04006395 A MXPA04006395 A MX PA04006395A MX PA04006395 A MXPA04006395 A MX PA04006395A MX PA04006395 A MXPA04006395 A MX PA04006395A
Authority
MX
Mexico
Prior art keywords
administration
nicotine
oral cavity
liquid pharmaceutical
pharmaceutical formulation
Prior art date
Application number
MXPA04006395A
Other languages
English (en)
Inventor
Schluter Anette
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20286485&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA04006395(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Publication of MXPA04006395A publication Critical patent/MXPA04006395A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se describe una formulacion farmaceutica que comprende nicotina en cualquier forma para la administracion de la cavidad oral siendo alcalizada por la estabilizacion y/o regulacion del pH. La administracion de preferencia es por aspersion y mas preferiblemente por aspersion bajo la lengua. Un metodo para fabricar dicha formulacion. El uso de dicha formulacion en terapia, tal como terapia para el tratamiento de la adiccion al tabaco.
MXPA04006395A 2001-12-27 2002-12-18 Una formulacion farmaceutica liquida que comprende nicotina para la administracion en la cavidad oral. MXPA04006395A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0104388A SE0104388D0 (sv) 2001-12-27 2001-12-27 New formulation and use and manufacture thereof
PCT/SE2002/002358 WO2003055486A1 (en) 2001-12-27 2002-12-18 A liquid pharmaceutical formulation comprising nicotine for the administration to the oral cavity

Publications (1)

Publication Number Publication Date
MXPA04006395A true MXPA04006395A (es) 2004-10-04

Family

ID=20286485

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04006395A MXPA04006395A (es) 2001-12-27 2002-12-18 Una formulacion farmaceutica liquida que comprende nicotina para la administracion en la cavidad oral.

Country Status (21)

Country Link
EP (2) EP2186507B1 (es)
JP (1) JP5264036B2 (es)
KR (1) KR20040075035A (es)
CN (1) CN1607950B (es)
AT (1) ATE427109T1 (es)
AU (1) AU2002359152B2 (es)
BR (1) BR0215393A (es)
CA (1) CA2471906C (es)
CY (1) CY1109146T1 (es)
DE (1) DE60231835D1 (es)
DK (2) DK1458388T3 (es)
ES (2) ES2537334T3 (es)
IL (1) IL162662A0 (es)
MX (1) MXPA04006395A (es)
NZ (1) NZ533714A (es)
PT (2) PT1458388E (es)
RU (1) RU2279871C2 (es)
SE (1) SE0104388D0 (es)
SI (1) SI1458388T1 (es)
WO (1) WO2003055486A1 (es)
ZA (1) ZA200404964B (es)

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ES2323228T3 (es) 2009-07-09
ES2537334T3 (es) 2015-06-05
JP2005518392A (ja) 2005-06-23
ZA200404964B (en) 2005-11-30
AU2002359152A1 (en) 2003-07-15
PT1458388E (pt) 2009-05-15
KR20040075035A (ko) 2004-08-26
EP2186507A2 (en) 2010-05-19
CA2471906A1 (en) 2003-07-10
CN1607950A (zh) 2005-04-20
DK1458388T3 (da) 2009-07-13
DK2186507T3 (en) 2015-06-15
IL162662A0 (en) 2005-11-20
EP2186507B1 (en) 2015-04-01
EP1458388A1 (en) 2004-09-22
RU2279871C2 (ru) 2006-07-20
SI1458388T1 (sl) 2009-08-31
PT2186507E (pt) 2015-06-24
JP5264036B2 (ja) 2013-08-14
BR0215393A (pt) 2004-12-07
NZ533714A (en) 2005-04-29
CA2471906C (en) 2012-10-16
AU2002359152B2 (en) 2006-11-09
CY1109146T1 (el) 2014-07-02
CN1607950B (zh) 2010-04-14
SE0104388D0 (sv) 2001-12-27
EP1458388B1 (en) 2009-04-01
DE60231835D1 (de) 2009-05-14
RU2004119434A (ru) 2005-04-20
WO2003055486A1 (en) 2003-07-10
EP2186507A3 (en) 2011-08-10

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