MXPA03010737A - Aril-8-azabiciclo(3.2.1) octanos para tratamiento de depresion. - Google Patents
Aril-8-azabiciclo(3.2.1) octanos para tratamiento de depresion.Info
- Publication number
- MXPA03010737A MXPA03010737A MXPA03010737A MXPA03010737A MXPA03010737A MX PA03010737 A MXPA03010737 A MX PA03010737A MX PA03010737 A MXPA03010737 A MX PA03010737A MX PA03010737 A MXPA03010737 A MX PA03010737A MX PA03010737 A MXPA03010737 A MX PA03010737A
- Authority
- MX
- Mexico
- Prior art keywords
- depression
- octanes
- azabicyclo
- aryl
- treatment
- Prior art date
Links
- 208000020401 Depressive disease Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 238000009472 formulation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
La presente invencion se refiere a compuestos de la formula (I), donde A, X, n, Ar1 y Ar2 estan definidas como en esta solicitud. Los compuestos pueden emplearse para tratar depresion. La invencion incluye tambien formulaciones conteniendo estos compuestos y procedimientos para preparar y usar compuestos inventivos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29356301P | 2001-05-25 | 2001-05-25 | |
| PCT/US2002/016008 WO2002096906A1 (en) | 2001-05-25 | 2002-05-20 | Aryl-8-azabicyclo[3.2.1]octanes for the treatment of depression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA03010737A true MXPA03010737A (es) | 2004-03-02 |
Family
ID=23129588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA03010737A MXPA03010737A (es) | 2001-05-25 | 2002-05-20 | Aril-8-azabiciclo(3.2.1) octanos para tratamiento de depresion. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6632824B2 (es) |
| EP (1) | EP1390364B1 (es) |
| JP (1) | JP2004533459A (es) |
| CN (1) | CN100408575C (es) |
| AR (1) | AR035898A1 (es) |
| AT (1) | ATE277924T1 (es) |
| BR (1) | BR0209995A (es) |
| CA (1) | CA2446532A1 (es) |
| DE (1) | DE60201440T2 (es) |
| DK (1) | DK1390364T3 (es) |
| ES (1) | ES2227468T3 (es) |
| MX (1) | MXPA03010737A (es) |
| TW (1) | TW589312B (es) |
| WO (1) | WO2002096906A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030130919A1 (en) * | 2001-11-20 | 2003-07-10 | Randy Templeton | Systems and methods for selectively accessing financial account information |
| US7873566B1 (en) | 2001-11-20 | 2011-01-18 | First Data Corporation | Systems and methods for selectively accessing or using financial account data for subsequent risk determination |
| US7668776B1 (en) | 2002-01-07 | 2010-02-23 | First Data Corporation | Systems and methods for selective use of risk models to predict financial risk |
| US7653590B1 (en) | 2002-01-14 | 2010-01-26 | First Data Corporation | System and method for overturning of risk evaluation performed by risk model to control financial risk |
| EP1496058A1 (en) * | 2003-07-09 | 2005-01-12 | Boehringer Ingelheim Pharma GmbH & Co.KG | Novel N-(heterobicycloalkanes)-substituted Indoles or heteroderivatives thereof |
| ATE465151T1 (de) | 2005-07-27 | 2010-05-15 | Hoffmann La Roche | 4-aryloxy-chinolin-derivate als 5-ht6-modulatoren |
| CN111217747B (zh) * | 2020-03-17 | 2022-02-22 | 济南韶远医药技术有限公司 | 一种扑疟喹啉的制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5340936A (en) | 1991-02-04 | 1994-08-23 | Hoechst-Roussel Pharmaceuticals Inc. | 8-azabicyclo[3.2.1]octane methanone and corresponding oximes |
| US5741789A (en) | 1995-01-17 | 1998-04-21 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
| US5627196A (en) | 1995-01-17 | 1997-05-06 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
| US5614523A (en) | 1995-01-17 | 1997-03-25 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
| US5789402A (en) | 1995-01-17 | 1998-08-04 | Eli Lilly Company | Compounds having effects on serotonin-related systems |
| BR9610960A (pt) | 1995-10-13 | 1999-03-02 | Neurosearch As | Derivados de 8-azabiciclo [3.2.1] oct -2- eno sua preparação e uso |
| NZ321970A (en) | 1995-11-02 | 2000-02-28 | Neurosearch As | Fused tropane-derivatives as neurotransmitter reuptake inhibitors |
| US5912256A (en) | 1996-06-20 | 1999-06-15 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
| CA2335336A1 (en) | 1998-06-19 | 1999-12-23 | James Edmund Audia | Inhibition of serotonin reuptake |
| GB9815317D0 (en) | 1998-07-15 | 1998-09-16 | Merck Sharp & Dohme | Therapeutic agents |
| US6432976B1 (en) * | 1999-10-29 | 2002-08-13 | Merck & Co., Inc. | 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists |
| AU1930901A (en) * | 1999-12-20 | 2001-07-03 | Eli Lilly And Company | Azabicyclo(3.2.1)octane derivatives |
-
2002
- 2002-05-14 TW TW091110010A patent/TW589312B/zh not_active IP Right Cessation
- 2002-05-14 AR ARP020101757A patent/AR035898A1/es not_active Application Discontinuation
- 2002-05-20 US US10/151,210 patent/US6632824B2/en not_active Expired - Fee Related
- 2002-05-20 AT AT02731881T patent/ATE277924T1/de not_active IP Right Cessation
- 2002-05-20 WO PCT/US2002/016008 patent/WO2002096906A1/en not_active Ceased
- 2002-05-20 CA CA002446532A patent/CA2446532A1/en not_active Abandoned
- 2002-05-20 EP EP02731881A patent/EP1390364B1/en not_active Expired - Lifetime
- 2002-05-20 DK DK02731881T patent/DK1390364T3/da active
- 2002-05-20 MX MXPA03010737A patent/MXPA03010737A/es active IP Right Grant
- 2002-05-20 DE DE60201440T patent/DE60201440T2/de not_active Expired - Fee Related
- 2002-05-20 BR BR0209995-0A patent/BR0209995A/pt not_active IP Right Cessation
- 2002-05-20 CN CNB028102614A patent/CN100408575C/zh not_active Expired - Fee Related
- 2002-05-20 ES ES02731881T patent/ES2227468T3/es not_active Expired - Lifetime
- 2002-05-20 JP JP2003500085A patent/JP2004533459A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1390364B1 (en) | 2004-09-29 |
| CN100408575C (zh) | 2008-08-06 |
| CA2446532A1 (en) | 2002-12-05 |
| CN1509287A (zh) | 2004-06-30 |
| WO2002096906A1 (en) | 2002-12-05 |
| JP2004533459A (ja) | 2004-11-04 |
| DE60201440T2 (de) | 2006-02-23 |
| US20030032645A1 (en) | 2003-02-13 |
| DK1390364T3 (da) | 2004-12-20 |
| AR035898A1 (es) | 2004-07-21 |
| ES2227468T3 (es) | 2005-04-01 |
| US6632824B2 (en) | 2003-10-14 |
| BR0209995A (pt) | 2004-04-06 |
| DE60201440D1 (de) | 2004-11-04 |
| TW589312B (en) | 2004-06-01 |
| EP1390364A1 (en) | 2004-02-25 |
| ATE277924T1 (de) | 2004-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |