MXPA03010655A - Gel oft??lmico de pirenzepina. - Google Patents
Gel oft??lmico de pirenzepina.Info
- Publication number
- MXPA03010655A MXPA03010655A MXPA03010655A MXPA03010655A MXPA03010655A MX PA03010655 A MXPA03010655 A MX PA03010655A MX PA03010655 A MXPA03010655 A MX PA03010655A MX PA03010655 A MXPA03010655 A MX PA03010655A MX PA03010655 A MXPA03010655 A MX PA03010655A
- Authority
- MX
- Mexico
- Prior art keywords
- ophthalmic gel
- pirenzepine
- pirenzepine ophthalmic
- gel
- pharmaceutically acceptable
- Prior art date
Links
- RMHMFHUVIITRHF-UHFFFAOYSA-N pirenzepine Chemical compound C1CN(C)CCN1CC(=O)N1C2=NC=CC=C2NC(=O)C2=CC=CC=C21 RMHMFHUVIITRHF-UHFFFAOYSA-N 0.000 title abstract 2
- 229960004633 pirenzepine Drugs 0.000 title abstract 2
- 229940100655 ophthalmic gel Drugs 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000001491 myopia Diseases 0.000 abstract 1
- 230000004379 myopia Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Es un objeto primario de la presente invencion proporcionar una formulacion oftalmica acuosa, para tratar la miopia, esta formulacion comprende la pirenzepina en combinacion con un portador de gel, aceptable farmaceuticamente.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29373101P | 2001-05-25 | 2001-05-25 | |
| PCT/US2002/013823 WO2002096418A1 (en) | 2001-05-25 | 2002-05-01 | Pirenzepine ophthalmic gel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA03010655A true MXPA03010655A (es) | 2007-06-22 |
Family
ID=23130330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA03010655A MXPA03010655A (es) | 2001-05-25 | 2002-05-01 | Gel oft??lmico de pirenzepina. |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20040137069A1 (es) |
| EP (1) | EP1397132A4 (es) |
| JP (1) | JP2004531569A (es) |
| KR (1) | KR20040018380A (es) |
| CN (1) | CN1509172A (es) |
| BR (1) | BR0210013A (es) |
| CA (1) | CA2447562A1 (es) |
| EC (1) | ECSP044862A (es) |
| HU (1) | HUP0304071A2 (es) |
| IL (1) | IL158904A0 (es) |
| MX (1) | MXPA03010655A (es) |
| NO (1) | NO20035224D0 (es) |
| NZ (1) | NZ529615A (es) |
| PL (1) | PL366924A1 (es) |
| RU (1) | RU2297831C2 (es) |
| WO (1) | WO2002096418A1 (es) |
| ZA (1) | ZA200309791B (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2573673A1 (en) | 2004-07-16 | 2006-01-26 | Proteosys Ag | Muscarinic antagonists with parp and sir modulating activity as cytoprotective agents |
| JP4963359B2 (ja) * | 2005-01-12 | 2012-06-27 | ロート製薬株式会社 | 眼局所適用製剤 |
| BRPI0709663A2 (pt) | 2006-03-31 | 2011-07-26 | Qlt Plug Delivery Inc | mÉtodos de liberaÇço de drogas, estruturas e composiÇÕes para um sistema nasolacrimal |
| CA2674076A1 (en) * | 2006-12-26 | 2008-07-10 | Qlt Plug Delivery, Inc. | Drug delivery implants for inhibition of optical defects |
| US10265265B2 (en) | 2007-03-15 | 2019-04-23 | Drug Delivery Solutions Limited | Topical composition |
| EP2008651A1 (en) | 2007-06-26 | 2008-12-31 | Drug Delivery Solutions Limited | A bioerodible patch |
| BRPI0817075A2 (pt) | 2007-09-07 | 2016-07-26 | Qlt Plug Delivery Inc | núcleos de fármaco para liberação prolongada de agentes terapêuticos |
| WO2010083129A2 (en) | 2009-01-13 | 2010-07-22 | The Regents Of The University Of California | Implantable delivery vehicle for ocular delivery of muscarinic antagonists |
| DK2632468T3 (en) | 2010-10-25 | 2018-02-12 | Univ Manitoba | THERAPEUTIC COMPOSITIONS FOR SYMMETRIC DIABETIC POLYNEuropathy |
| HRP20191711T1 (hr) * | 2011-03-14 | 2019-12-13 | Drug Delivery Solutions Ltd | Oftalmološki pripravak |
| RU2635185C2 (ru) * | 2013-12-17 | 2017-11-09 | Иван Дмитриевич Захаров | Фармацевтический препарат для профилактики и лечения прогрессирующей близорукости |
| US9421199B2 (en) | 2014-06-24 | 2016-08-23 | Sydnexis, Inc. | Ophthalmic composition |
| WO2016172712A2 (en) | 2015-04-23 | 2016-10-27 | Sydnexis, Inc. | Ophthalmic composition |
| EP3302426A4 (en) | 2015-05-29 | 2018-12-05 | Sydnexis, Inc. | D2o stabilized pharmaceutical formulations |
| CN105663137A (zh) * | 2016-01-14 | 2016-06-15 | 王真 | 哌仑西平在制备治疗脓毒症疾病的药物中的应用 |
| SG11201809822SA (en) * | 2016-05-25 | 2018-12-28 | Singapore Health Serv Pte Ltd | Atropine-containing aqueous composition |
| WO2019087146A1 (en) | 2017-11-03 | 2019-05-09 | Novartis Ag | Azabicyclo and diazepine derivatives for treating ocular disorders |
| EP3542788A1 (en) | 2018-03-19 | 2019-09-25 | MC2 Therapeutics Limited | Topical composition comprising calcipotriol and betamethasone dipropionate |
| JP7407462B2 (ja) * | 2019-03-26 | 2024-01-04 | ウィンサンター・インコーポレイテッド | 末梢神経障害の処置のための局所製剤 |
| CA3142885A1 (en) * | 2019-06-10 | 2020-12-17 | Jenivision Inc. | Methods and formulations for treating vision disorders |
| WO2021007578A1 (en) * | 2019-07-11 | 2021-01-14 | University Of Utah Research Foundation | Multi-agent ocular formulations and treatment methods |
| KR102808906B1 (ko) * | 2021-06-18 | 2025-05-19 | 대우제약 주식회사 | 고점도 점안제를 무균여과하는 방법 |
| CN117338787A (zh) * | 2023-11-24 | 2024-01-05 | 南京恒道医药科技股份有限公司 | 一种眼用药物组合物及其制备方法 |
| WO2025171327A1 (en) * | 2024-02-09 | 2025-08-14 | Levation Pharma Ltd. | Methods for producing dermatological gel compositions |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU188852B (en) * | 1983-03-16 | 1986-05-28 | Richter Gedeon Vegyeszeti Gyar Rt,Hu | Process for producing thiazolidine derivatives active against gastric ulcer and intestinal ulcer |
| US4865599A (en) * | 1986-08-18 | 1989-09-12 | Houston Biotechnology, Inc. | Ophthalmic compositions for treating nerve degeneration |
| CA1336490C (en) * | 1988-06-03 | 1995-08-01 | Paul Michael Iuvone | Pharmacological treatment of ocular development |
| US5360801A (en) * | 1989-06-21 | 1994-11-01 | The Trustees Of The University Of Pennsylvania | Pharmacological stimulation of eye growth |
| US5122522A (en) * | 1989-06-21 | 1992-06-16 | The Trustees Of The University Of Pennsylvania | Treatment and control of ocular development |
| JP3165436B2 (ja) * | 1989-06-21 | 2001-05-14 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルベニア | 眼の発達の治療及び制御 |
| US5055302A (en) * | 1990-02-22 | 1991-10-08 | Trustees Of The University Of Pennsylvania | Neuropeptide control of ocular growth |
| SU1827797A3 (ru) * | 1991-04-30 | 1996-05-20 | Н.Б. Леонидов | Лекарственный препарат для анестезии глаз |
| US5461808A (en) * | 1993-02-08 | 1995-10-31 | Fritts; Robert W. | Table top backlit display |
| US5385939A (en) * | 1993-04-30 | 1995-01-31 | The Trustees Of The University Of Pennsylvania | GABA-ergic modulation of eye growth |
| US5461052A (en) * | 1993-04-30 | 1995-10-24 | The Trustees Of The University Of Pennsylvania | Prevention of myopia by tricyclic compounds |
| US5516808A (en) * | 1994-10-27 | 1996-05-14 | Sawaya; Assad S. | Topical cellulose pharmaceutical formulation |
| US5888493A (en) * | 1996-12-05 | 1999-03-30 | Sawaya; Assad S. | Ophthalmic aqueous gel formulation and related methods |
| RU2135129C1 (ru) * | 1998-11-18 | 1999-08-27 | Ларионов Евгений Викторович | Глазные капли "корнеалон-плюс" |
| US6164282A (en) * | 1999-01-27 | 2000-12-26 | Allergan Sales, Inc. | Methods for restoring and/or enhancing accommodation in pseudo phakia |
-
2002
- 2002-05-01 WO PCT/US2002/013823 patent/WO2002096418A1/en not_active Ceased
- 2002-05-01 CA CA002447562A patent/CA2447562A1/en not_active Abandoned
- 2002-05-01 JP JP2002592928A patent/JP2004531569A/ja not_active Withdrawn
- 2002-05-01 EP EP02734130A patent/EP1397132A4/en not_active Withdrawn
- 2002-05-01 PL PL02366924A patent/PL366924A1/xx not_active Application Discontinuation
- 2002-05-01 HU HU0304071A patent/HUP0304071A2/hu unknown
- 2002-05-01 BR BR0210013-4A patent/BR0210013A/pt not_active IP Right Cessation
- 2002-05-01 RU RU2003136735/15A patent/RU2297831C2/ru not_active IP Right Cessation
- 2002-05-01 MX MXPA03010655A patent/MXPA03010655A/es not_active Application Discontinuation
- 2002-05-01 NZ NZ529615A patent/NZ529615A/en unknown
- 2002-05-01 KR KR10-2003-7015393A patent/KR20040018380A/ko not_active Ceased
- 2002-05-01 CN CNA02810174XA patent/CN1509172A/zh active Pending
- 2002-05-01 IL IL15890402A patent/IL158904A0/xx unknown
-
2003
- 2003-10-31 US US10/698,320 patent/US20040137069A1/en not_active Abandoned
- 2003-11-24 NO NO20035224A patent/NO20035224D0/no not_active Application Discontinuation
- 2003-12-18 ZA ZA200309791A patent/ZA200309791B/xx unknown
-
2004
- 2004-01-23 EC EC2004004862A patent/ECSP044862A/es unknown
-
2006
- 2006-04-07 US US11/400,635 patent/US20060188576A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| RU2003136735A (ru) | 2005-03-27 |
| RU2297831C2 (ru) | 2007-04-27 |
| NO20035224D0 (no) | 2003-11-24 |
| EP1397132A1 (en) | 2004-03-17 |
| ZA200309791B (en) | 2004-10-04 |
| WO2002096418A1 (en) | 2002-12-05 |
| CA2447562A1 (en) | 2002-12-05 |
| CN1509172A (zh) | 2004-06-30 |
| BR0210013A (pt) | 2004-08-10 |
| PL366924A1 (en) | 2005-02-07 |
| US20040137069A1 (en) | 2004-07-15 |
| ECSP044862A (es) | 2004-03-23 |
| US20060188576A1 (en) | 2006-08-24 |
| NZ529615A (en) | 2005-07-29 |
| EP1397132A4 (en) | 2006-12-13 |
| HUP0304071A2 (hu) | 2004-04-28 |
| IL158904A0 (en) | 2004-05-12 |
| KR20040018380A (ko) | 2004-03-03 |
| JP2004531569A (ja) | 2004-10-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |