MXPA03010440A - Derivados de 4-(fenil-(piperidin-4-il)amino)-benzamida y su uso para tratamiento del dolor, ansiedad o trastornos gastrointestinales. - Google Patents
Derivados de 4-(fenil-(piperidin-4-il)amino)-benzamida y su uso para tratamiento del dolor, ansiedad o trastornos gastrointestinales.Info
- Publication number
- MXPA03010440A MXPA03010440A MXPA03010440A MXPA03010440A MXPA03010440A MX PA03010440 A MXPA03010440 A MX PA03010440A MX PA03010440 A MXPA03010440 A MX PA03010440A MX PA03010440 A MXPA03010440 A MX PA03010440A MX PA03010440 A MXPA03010440 A MX PA03010440A
- Authority
- MX
- Mexico
- Prior art keywords
- phenyl
- anxiety
- pain
- gastrointestinal disorders
- ring
- Prior art date
Links
- 208000019901 Anxiety disease Diseases 0.000 title abstract 2
- 208000018522 Gastrointestinal disease Diseases 0.000 title abstract 2
- 208000027520 Somatoform disease Diseases 0.000 title abstract 2
- 230000036506 anxiety Effects 0.000 title abstract 2
- 230000036407 pain Effects 0.000 title abstract 2
- 208000027753 pain disease Diseases 0.000 title abstract 2
- YFKZHFPNQFEPHF-UHFFFAOYSA-N 4-(n-piperidin-4-ylanilino)benzamide Chemical compound C1=CC(C(=O)N)=CC=C1N(C=1C=CC=CC=1)C1CCNCC1 YFKZHFPNQFEPHF-UHFFFAOYSA-N 0.000 title 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- -1 C1-C6alkoxy Chemical group 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 125000002883 imidazolyl group Chemical group 0.000 abstract 1
- 125000002346 iodo group Chemical group I* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- ILVXOBCQQYKLDS-UHFFFAOYSA-N pyridine N-oxide Chemical compound [O-][N+]1=CC=CC=C1 ILVXOBCQQYKLDS-UHFFFAOYSA-N 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000000168 pyrrolyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
- 125000001425 triazolyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Se describen y se reclaman en la presente solicitud, los compuestos de la formula general I donde R1 se selecciona de cualquiera de fenilo, piridinilo, pirrolilo, tienilo, furanilo, imidazolilo, triazolilo, piridil-N-bxido; donde cada anillo fenilo R' y anillo heteroaromatico R1 puede ser sustituido opcional e independientemente ademas por 1, 2 o 3 sustituyentes seleccionados de alquilo de 1 a 6 atomos de carbono de cadena recta o ramificada, NO2, CF3, alcoxi de 1 a atomos de carbono, cloro, fluoro, bromo y yodo. Las sustituciones en el anillo fenilo y en el anillo heteroaromatico pueden tomar lugar en cualquier posicion en los sistemas de anillos; asi como tambien sus sales farmaceuticamente aceptables y composiciones farmaceuticas que comprenden los compuestos novedosos y su uso en la terapia, en particular en el manejo del dolor, ansiedad y trastornos gastrointestinales, funcionales.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0101769A SE0101769D0 (sv) | 2001-05-18 | 2001-05-18 | Novel compounds |
| PCT/SE2002/000944 WO2002094782A1 (en) | 2001-05-18 | 2002-05-16 | 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derativatives and their use for the treatment of pain, anxiety or gastrointestinal disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA03010440A true MXPA03010440A (es) | 2004-03-09 |
Family
ID=20284172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA03010440A MXPA03010440A (es) | 2001-05-18 | 2002-05-16 | Derivados de 4-(fenil-(piperidin-4-il)amino)-benzamida y su uso para tratamiento del dolor, ansiedad o trastornos gastrointestinales. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US7226933B2 (es) |
| EP (1) | EP1395555B1 (es) |
| JP (1) | JP2005508289A (es) |
| KR (1) | KR20030094425A (es) |
| CN (1) | CN1639123A (es) |
| AR (1) | AR033758A1 (es) |
| AT (1) | ATE313528T1 (es) |
| BG (1) | BG108330A (es) |
| BR (1) | BR0209670A (es) |
| CA (1) | CA2446311A1 (es) |
| CO (1) | CO5540317A2 (es) |
| CZ (1) | CZ20033089A3 (es) |
| DE (1) | DE60208192T2 (es) |
| EE (1) | EE200300554A (es) |
| HU (1) | HUP0401328A2 (es) |
| IL (1) | IL158628A0 (es) |
| IS (1) | IS7028A (es) |
| MX (1) | MXPA03010440A (es) |
| NO (1) | NO20035113D0 (es) |
| NZ (1) | NZ529398A (es) |
| PL (1) | PL366387A1 (es) |
| RU (1) | RU2003131966A (es) |
| SE (1) | SE0101769D0 (es) |
| SK (1) | SK13912003A3 (es) |
| WO (1) | WO2002094782A1 (es) |
| ZA (1) | ZA200308631B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003076400A1 (en) * | 2002-03-13 | 2003-09-18 | Janssen Pharmaceutica N.V. | New inhibitors of histone deacetylase |
| SE0300987D0 (sv) * | 2003-04-03 | 2003-04-03 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| KR101255074B1 (ko) | 2003-10-01 | 2013-04-16 | 아돌로 코포레이션 | 스피로시클릭 헤테로시클릭 유도체 및 이의 사용 방법 |
| US7598261B2 (en) | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| US7576207B2 (en) * | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| JP2010503669A (ja) * | 2006-09-12 | 2010-02-04 | アドラー コーポレーション | 認知機能の強化のためのｎ含有スピロ化合物の使用 |
| CN107531670B (zh) * | 2014-12-19 | 2020-12-15 | 菲勒诺沃公司 | 二芳基亚甲基哌啶衍生物及其作为δ阿片受体激动剂的用途 |
| US20250084091A1 (en) * | 2021-05-04 | 2025-03-13 | The Texas A&M University System | Inhibitors of sars-cov-2 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4091096A (en) | 1976-03-19 | 1978-05-23 | Eli Lilly And Company | Dinitroanilines for the control of phytopathogens |
| EG12406A (en) | 1976-08-12 | 1979-03-31 | Janssen Pharmaceutica Nv | Process for preparing of novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides |
| US4252812A (en) | 1977-05-23 | 1981-02-24 | Pfizer Inc. | 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles |
| SE441448B (sv) | 1977-05-23 | 1985-10-07 | Pfizer | Sett att framstella hexahydro-gamma-karbolinforeningar |
| DE3200304A1 (de) | 1981-01-16 | 1982-08-26 | Sandoz-Patent-GmbH, 7850 Lörrach | 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel |
| EP0181793B1 (fr) | 1984-10-16 | 1988-07-27 | Synthelabo | Dérivés de pipéridine, leur préparation et leur application en thérapeutique |
| KR940003491B1 (ko) | 1989-08-10 | 1994-04-23 | 리히터 게데온 베기에스제티 기아르 알.티 | 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물 |
| YU150489A (sh) | 1989-08-10 | 1992-12-21 | W.L. Gore & Co. Gmbh. | Uređaj za ispitivanje odevnih predmeta na nepromočivost |
| US5854245A (en) | 1996-06-28 | 1998-12-29 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| TW548271B (en) * | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
| SE9604786D0 (sv) * | 1996-12-20 | 1996-12-20 | Astra Pharma Inc | New compounds |
| EP1049676B1 (en) | 1997-12-24 | 2005-10-12 | Ortho-Mcneil Pharmaceutical, Inc. | 4- aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor |
| CA2683097A1 (en) | 1998-03-10 | 1999-09-16 | Research Triangle Institute | Novel opiate compounds, methods of making and methods of use |
| SE9904675D0 (sv) * | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
| CN1426411A (zh) * | 2000-03-03 | 2003-06-25 | 奥索-麦克尼尔药品公司 | 3－(二芳基亚甲基)－8－氮杂双环[3.2.1]辛烷衍生物 |
| SE0001207D0 (sv) * | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
| WO2009028275A1 (ja) * | 2007-08-28 | 2009-03-05 | Konica Minolta Medical & Graphic, Inc. | シンチレータパネル |
-
2001
- 2001-05-18 SE SE0101769A patent/SE0101769D0/xx unknown
-
2002
- 2002-05-16 CZ CZ20033089A patent/CZ20033089A3/cs unknown
- 2002-05-16 DE DE60208192T patent/DE60208192T2/de not_active Expired - Fee Related
- 2002-05-16 RU RU2003131966/04A patent/RU2003131966A/ru not_active Application Discontinuation
- 2002-05-16 KR KR10-2003-7014946A patent/KR20030094425A/ko not_active Withdrawn
- 2002-05-16 PL PL02366387A patent/PL366387A1/xx not_active Application Discontinuation
- 2002-05-16 CN CNA028141601A patent/CN1639123A/zh active Pending
- 2002-05-16 WO PCT/SE2002/000944 patent/WO2002094782A1/en not_active Ceased
- 2002-05-16 MX MXPA03010440A patent/MXPA03010440A/es unknown
- 2002-05-16 BR BR0209670-6A patent/BR0209670A/pt not_active IP Right Cessation
- 2002-05-16 AT AT02733702T patent/ATE313528T1/de not_active IP Right Cessation
- 2002-05-16 EE EEP200300554A patent/EE200300554A/xx unknown
- 2002-05-16 EP EP02733702A patent/EP1395555B1/en not_active Expired - Lifetime
- 2002-05-16 SK SK1391-2003A patent/SK13912003A3/sk unknown
- 2002-05-16 NZ NZ529398A patent/NZ529398A/en unknown
- 2002-05-16 JP JP2002591455A patent/JP2005508289A/ja active Pending
- 2002-05-16 IL IL15862802A patent/IL158628A0/xx unknown
- 2002-05-16 CA CA002446311A patent/CA2446311A1/en not_active Abandoned
- 2002-05-16 AR ARP020101814A patent/AR033758A1/es unknown
- 2002-05-16 HU HU0401328A patent/HUP0401328A2/hu unknown
- 2002-05-16 US US10/477,852 patent/US7226933B2/en not_active Expired - Fee Related
-
2003
- 2003-11-05 ZA ZA200308631A patent/ZA200308631B/xx unknown
- 2003-11-07 BG BG108330A patent/BG108330A/bg unknown
- 2003-11-12 CO CO03100165A patent/CO5540317A2/es not_active Application Discontinuation
- 2003-11-12 IS IS7028A patent/IS7028A/is unknown
- 2003-11-17 NO NO20035113A patent/NO20035113D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EE200300554A (et) | 2004-02-16 |
| ATE313528T1 (de) | 2006-01-15 |
| US20040235897A1 (en) | 2004-11-25 |
| US7226933B2 (en) | 2007-06-05 |
| BR0209670A (pt) | 2004-04-20 |
| CA2446311A1 (en) | 2002-11-28 |
| RU2003131966A (ru) | 2005-05-10 |
| HUP0401328A2 (hu) | 2004-12-28 |
| EP1395555B1 (en) | 2005-12-21 |
| SK13912003A3 (sk) | 2004-04-06 |
| SE0101769D0 (sv) | 2001-05-18 |
| JP2005508289A (ja) | 2005-03-31 |
| EP1395555A1 (en) | 2004-03-10 |
| AR033758A1 (es) | 2004-01-07 |
| IL158628A0 (en) | 2004-05-12 |
| WO2002094782A1 (en) | 2002-11-28 |
| DE60208192D1 (de) | 2006-01-26 |
| KR20030094425A (ko) | 2003-12-11 |
| ZA200308631B (en) | 2005-02-07 |
| NO20035113D0 (no) | 2003-11-17 |
| DE60208192T2 (de) | 2006-07-13 |
| CN1639123A (zh) | 2005-07-13 |
| CO5540317A2 (es) | 2005-07-29 |
| IS7028A (is) | 2003-11-12 |
| NZ529398A (en) | 2005-08-26 |
| CZ20033089A3 (en) | 2004-06-16 |
| PL366387A1 (en) | 2005-01-24 |
| BG108330A (bg) | 2004-12-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MXPA03010445A (es) | Derivados de 4(fenil-piperazinil-metil) benzamida y su uso para tratamiento del dolor, ansiedad o trastornos gastrointestinales. | |
| SE0001207D0 (sv) | Novel compounds | |
| MXPA03010439A (es) | Derivados de 4-(fenil-piperidin-a-iliden-metil)-benzamida y su uso para tratar dolor, ansiedad o trastornos gastrointestinales. | |
| MXPA04003056A (es) | Derivados de 4?piperidin-4-iliden-(3-carbamoilfenil)metil? benzamida y su uso para tratamiento de dolor, lesiones espinales o transtornos gastrointestinales. | |
| MY134568A (en) | Cb2 receptor agonists | |
| NO20061454L (no) | Compounds having CRTH2 antagonist activity | |
| NO20035036D0 (no) | Tartratsalter av 5,8,14-triazatetracyklo (10.3.1.02,11.04.9)- heksadeka-2 (11),3,5,7,9-pentaen og farmasöytiske sammensetningerderav | |
| SE0401345D0 (sv) | Therapeutic compounds: Pyridine as scaffold | |
| SE0402762D0 (sv) | Indazole sulphonamide derivatives | |
| SE0302573D0 (sv) | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof | |
| MXPA03010443A (es) | Derivados de 4-(fenil-piperidin-4-iliden-metil)-benzamida y su uso para tratar dolor, ansiedad o trastornos gastrointestinales. | |
| SE0001208D0 (sv) | Novel compounds | |
| MXPA03010440A (es) | Derivados de 4-(fenil-(piperidin-4-il)amino)-benzamida y su uso para tratamiento del dolor, ansiedad o trastornos gastrointestinales. | |
| MXPA03010437A (es) | Derivados de 4-(fenil-piperidin-4-iliden-metil)-benzamida y su uso para tratar dolor, ansiedad o transtornos gastrointestinales. | |
| WO2004041802A8 (en) | 4(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders | |
| CA2393568A1 (en) | Diarylmethylpiperazines | |
| SE9902267D0 (sv) | New compounds | |
| SE0001209D0 (sv) | Novel compounds | |
| BG106807A (en) | Novel compounds | |
| MXPA03010442A (es) | Derivados de 4-(fenil-(piperidin-4-il)-amino)-benzamida y sus usos para tratamiento de dolor, ansiedad o desordenes gastrointestinales. | |
| MXPA03010441A (es) | Derivados de 4-(fenil-(piperidin-4-il)-amino)-benzamida y sus usos para tratamiento del dolor, ansiedad o desordenes gastrointestinales. | |
| MXPA03010438A (es) | Derivados de 4-(fenil-piperidin-4-iliden-metil)-benzamida y su uso para tratar dolor, ansiedad o transtornos gastrointestinales. | |
| ATE384049T1 (de) | Therapeutische heterocyclen als bradykinin b2 rezeptor antagonisten | |
| MXPA03010444A (es) | Derivados de 4-(fenil-(piperidin-4-il)-amino)-benzamida y sus usos para tratamiento del dolor, ansiedad o trastornos gastrointestinales. | |
| DE602004019939D1 (de) | Thiazolderivate als npy-antagonisten |