MXPA03005914A - Moduladores de canales de sodio derivados de 2-piperidimidazoles. - Google Patents
Moduladores de canales de sodio derivados de 2-piperidimidazoles.Info
- Publication number
- MXPA03005914A MXPA03005914A MXPA03005914A MXPA03005914A MXPA03005914A MX PA03005914 A MXPA03005914 A MX PA03005914A MX PA03005914 A MXPA03005914 A MX PA03005914A MX PA03005914 A MXPA03005914 A MX PA03005914A MX PA03005914 A MXPA03005914 A MX PA03005914A
- Authority
- MX
- Mexico
- Prior art keywords
- piperidylimidazoles
- sodium channel
- channel modulators
- modulators derived
- derived
- Prior art date
Links
- GJQDDUPLCDQOHZ-UHFFFAOYSA-N 2-(1h-imidazol-2-yl)piperidine Chemical class N1CCCCC1C1=NC=CN1 GJQDDUPLCDQOHZ-UHFFFAOYSA-N 0.000 title 1
- 108010052164 Sodium Channels Proteins 0.000 title 1
- 102000018674 Sodium Channels Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0017149A FR2818978B1 (fr) | 2000-12-28 | 2000-12-28 | Modulateurs de canaux sodiques derives de 2-piperidylimidazoles |
| PCT/FR2001/004209 WO2002053559A1 (fr) | 2000-12-28 | 2001-12-27 | Modulateurs de canaux sodiques derives de 2-piperidylimidazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA03005914A true MXPA03005914A (es) | 2003-09-10 |
Family
ID=8858291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA03005914A MXPA03005914A (es) | 2000-12-28 | 2001-12-27 | Moduladores de canales de sodio derivados de 2-piperidimidazoles. |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20040077640A1 (es) |
| EP (1) | EP1349850B1 (es) |
| JP (1) | JP2004517121A (es) |
| KR (1) | KR100892656B1 (es) |
| CN (1) | CN1214025C (es) |
| AR (1) | AR035613A1 (es) |
| AT (1) | ATE304005T1 (es) |
| AU (1) | AU2002228128B8 (es) |
| BR (1) | BR0116581A (es) |
| CA (1) | CA2432959A1 (es) |
| CZ (1) | CZ20032053A3 (es) |
| DE (1) | DE60113297T2 (es) |
| DK (1) | DK1349850T3 (es) |
| ES (1) | ES2249488T3 (es) |
| FR (1) | FR2818978B1 (es) |
| HU (1) | HUP0600032A2 (es) |
| IL (1) | IL156352A0 (es) |
| MX (1) | MXPA03005914A (es) |
| NO (1) | NO20032904D0 (es) |
| NZ (1) | NZ526394A (es) |
| PL (1) | PL363640A1 (es) |
| RU (1) | RU2275369C2 (es) |
| WO (1) | WO2002053559A1 (es) |
| ZA (1) | ZA200305005B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008001596A (ja) * | 2004-09-03 | 2008-01-10 | Astellas Pharma Inc | ナトリウムチャネル阻害剤 |
| BRPI0620239B8 (pt) * | 2005-12-22 | 2021-05-25 | Newron Pharm Spa | derivados de 2-feniletilamino. |
| CA2647603A1 (en) | 2006-03-27 | 2007-10-04 | Toray Industries, Inc. | Ureide derivative and use thereof for medical purposes |
| DE102007047243A1 (de) | 2007-09-25 | 2009-04-02 | Karl Storz Gmbh & Co. Kg | Bipolares medizinisches Instrument |
| BRPI0905759A2 (pt) * | 2008-01-25 | 2015-07-14 | Du Pont | Composto selecionado a partir dos compostos de fórmula 1 e n óxidos e sais dos mesmos, método para controlar doenças de planta causadas por patógenos de planta fúngicos oomycota e composição fungicida |
| WO2025122832A1 (en) * | 2023-12-07 | 2025-06-12 | Genep Inc. | Imidazole compounds and their use as sodium channel inhibitors |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07509219A (ja) * | 1992-04-01 | 1995-10-12 | ザ ユニバーシティー オブ トレド | H↓3受容体アンタゴニストとしての4−[4’−ピペリジニルまたは3’−ピロリジニル]置換イミダゾールおよび治療上のその使用方法 |
| US5296609A (en) * | 1993-04-09 | 1994-03-22 | Syntex Pharmaceuticals, Ltd. | Process for the preparation of 1,2,4-substituted imidazoles and related aminoalkylimidazole derivatives |
| EP0793653A1 (en) * | 1994-11-23 | 1997-09-10 | Neurogen Corporation | Certain 4-aminomethyl-2-substituted imidazole derivatives and 2-aminomethyl-4-substituted imidazole derivatives; new classes of dopamine receptor subtype specific ligands |
| ATE433446T1 (de) * | 1995-10-06 | 2009-06-15 | Merck & Co Inc | Substituierte imidazole mit krebsremmender und cytokininhibierender wirkung |
| EP0906307B1 (en) * | 1996-06-10 | 2005-04-27 | Merck & Co., Inc. | Substituted imidazoles having cytokine inhibitory activity |
| AU761020B2 (en) * | 1998-06-12 | 2003-05-29 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Beta-carboline compounds |
| BR0009322A (pt) * | 1999-03-26 | 2002-04-30 | Euro Celtique Sa | Pirazóis, imidazóis, oxazóis, tiazóis e pirróis substituìdos com arila e o uso dos mesmos |
| US6297256B1 (en) * | 1999-06-15 | 2001-10-02 | Neurogen Corporation | Aryl and heteroaryl substituted pyridino derivatives GABA brain receptor ligands |
| TWI292316B (en) * | 1999-10-11 | 2008-01-11 | Sod Conseils Rech Applic | Pharmaceutical composition of thiazole derivatives intended to inhibit mao and/or lipidic peroxidation and/or to act as modulators of sodium channels and the use thereof |
| HK1045503A1 (zh) * | 1999-12-16 | 2002-11-29 | Schering Corporation | 取代的咪唑神经肽yy5受体拮抗物 |
-
2000
- 2000-12-28 FR FR0017149A patent/FR2818978B1/fr not_active Expired - Fee Related
-
2001
- 2001-12-27 DE DE60113297T patent/DE60113297T2/de not_active Expired - Fee Related
- 2001-12-27 US US10/450,215 patent/US20040077640A1/en not_active Abandoned
- 2001-12-27 RU RU2003123119/04A patent/RU2275369C2/ru not_active IP Right Cessation
- 2001-12-27 BR BR0116581-0A patent/BR0116581A/pt not_active IP Right Cessation
- 2001-12-27 KR KR1020037008737A patent/KR100892656B1/ko not_active Expired - Fee Related
- 2001-12-27 CZ CZ20032053A patent/CZ20032053A3/cs unknown
- 2001-12-27 MX MXPA03005914A patent/MXPA03005914A/es active IP Right Grant
- 2001-12-27 CN CNB018215203A patent/CN1214025C/zh not_active Expired - Fee Related
- 2001-12-27 AT AT01989665T patent/ATE304005T1/de not_active IP Right Cessation
- 2001-12-27 DK DK01989665T patent/DK1349850T3/da active
- 2001-12-27 ES ES01989665T patent/ES2249488T3/es not_active Expired - Lifetime
- 2001-12-27 CA CA002432959A patent/CA2432959A1/fr not_active Abandoned
- 2001-12-27 WO PCT/FR2001/004209 patent/WO2002053559A1/fr not_active Ceased
- 2001-12-27 AU AU2002228128A patent/AU2002228128B8/en not_active Ceased
- 2001-12-27 NZ NZ526394A patent/NZ526394A/xx unknown
- 2001-12-27 EP EP01989665A patent/EP1349850B1/fr not_active Expired - Lifetime
- 2001-12-27 JP JP2002554678A patent/JP2004517121A/ja active Pending
- 2001-12-27 PL PL01363640A patent/PL363640A1/xx not_active Application Discontinuation
- 2001-12-27 HU HU0600032A patent/HUP0600032A2/hu unknown
- 2001-12-27 IL IL15635201A patent/IL156352A0/xx unknown
- 2001-12-28 AR ARP010106102A patent/AR035613A1/es unknown
-
2003
- 2003-06-24 NO NO20032904A patent/NO20032904D0/no not_active Application Discontinuation
- 2003-06-26 ZA ZA200305005A patent/ZA200305005B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60113297T2 (de) | 2006-07-13 |
| FR2818978A1 (fr) | 2002-07-05 |
| AU2002228128B2 (en) | 2006-08-03 |
| ZA200305005B (en) | 2004-06-28 |
| EP1349850A1 (fr) | 2003-10-08 |
| PL363640A1 (en) | 2004-11-29 |
| KR100892656B1 (ko) | 2009-04-15 |
| BR0116581A (pt) | 2004-01-06 |
| EP1349850B1 (fr) | 2005-09-07 |
| CA2432959A1 (fr) | 2002-07-11 |
| WO2002053559A1 (fr) | 2002-07-11 |
| FR2818978B1 (fr) | 2003-02-28 |
| DE60113297D1 (de) | 2005-10-13 |
| NO20032904L (no) | 2003-06-24 |
| NZ526394A (en) | 2004-12-24 |
| CZ20032053A3 (en) | 2004-04-14 |
| RU2003123119A (ru) | 2005-01-10 |
| HK1059784A1 (en) | 2004-07-16 |
| IL156352A0 (en) | 2004-01-04 |
| AU2002228128B8 (en) | 2007-01-04 |
| KR20030070592A (ko) | 2003-08-30 |
| HUP0600032A2 (en) | 2006-06-28 |
| ES2249488T3 (es) | 2006-04-01 |
| DK1349850T3 (da) | 2006-01-23 |
| RU2275369C2 (ru) | 2006-04-27 |
| NO20032904D0 (no) | 2003-06-24 |
| AU2002228128A1 (en) | 2002-07-16 |
| AR035613A1 (es) | 2004-06-16 |
| CN1483029A (zh) | 2004-03-17 |
| JP2004517121A (ja) | 2004-06-10 |
| ATE304005T1 (de) | 2005-09-15 |
| CN1214025C (zh) | 2005-08-10 |
| US20040077640A1 (en) | 2004-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration | ||
| HC | Change of company name or juridical status |