MXPA02012750A - Compuestos farmaceuticos antagonistas del receptor de la vitronectina para su uso en terapia de combinacion. - Google Patents
Compuestos farmaceuticos antagonistas del receptor de la vitronectina para su uso en terapia de combinacion.Info
- Publication number
- MXPA02012750A MXPA02012750A MXPA02012750A MXPA02012750A MXPA02012750A MX PA02012750 A MXPA02012750 A MX PA02012750A MX PA02012750 A MXPA02012750 A MX PA02012750A MX PA02012750 A MXPA02012750 A MX PA02012750A MX PA02012750 A MXPA02012750 A MX PA02012750A
- Authority
- MX
- Mexico
- Prior art keywords
- combination therapy
- receptor antagonist
- vitronectin receptor
- pharmaceuticals
- treatment
- Prior art date
Links
- 238000002648 combination therapy Methods 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 102100022337 Integrin alpha-V Human genes 0.000 title 1
- 108010048673 Vitronectin Receptors Proteins 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 125000005647 linker group Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 230000008685 targeting Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invencion describe kit(s) novedosos que comprenden compuestos de la formula (I): (Q)d-Ln-Ch o (Q)d-Ln-(Ch)d' util para el diagnostico y tratamiento del cancer en terapia de combinacion en un paciente. La presente invencion proporciona compuestos novedosos utiles para el tratamiento de la artritis reumatoide. Los ingredientes farmaceuticos comprenden una porcion objetivo que se enlaza al receptor que se sobreregula durante la angiogenesis, un grupo de enlace opcional, y un radioisotopo terapeuticamente efectivo o porcion formadora de imagen diagnosticamente efectiva.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21321000P | 2000-06-21 | 2000-06-21 | |
| PCT/US2001/019793 WO2001097848A2 (en) | 2000-06-21 | 2001-06-21 | Vitronectin receptor antagonist pharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA02012750A true MXPA02012750A (es) | 2004-07-30 |
Family
ID=22794168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA02012750A MXPA02012750A (es) | 2000-06-21 | 2001-06-21 | Compuestos farmaceuticos antagonistas del receptor de la vitronectina para su uso en terapia de combinacion. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1307226B1 (es) |
| JP (1) | JP2004521066A (es) |
| CN (1) | CN1582166A (es) |
| AT (1) | ATE414541T1 (es) |
| AU (2) | AU7296501A (es) |
| BR (1) | BR0111880A (es) |
| CA (1) | CA2412854C (es) |
| DE (1) | DE60136632D1 (es) |
| IL (1) | IL152941A0 (es) |
| MX (1) | MXPA02012750A (es) |
| NZ (1) | NZ522925A (es) |
| WO (1) | WO2001097848A2 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6569402B1 (en) | 1998-12-18 | 2003-05-27 | Bristol-Myers Squibb Pharma Company | Vitronectin receptor antagonist pharmaceuticals |
| CA2408323C (en) | 2000-05-08 | 2012-06-12 | The University Of British Columbia | Drug delivery systems for photodynamic therapy |
| CA2412849A1 (en) * | 2000-06-21 | 2001-12-27 | Bristol-Myers Squibb Pharma Company | Vitronectin receptor antagonist pharmaceuticals for use in combination therapy |
| KR100978126B1 (ko) | 2002-01-24 | 2010-08-26 | 반즈 쥬이쉬 하스피털 | 인테그린 표적화 조영제 |
| EP1475105A1 (en) * | 2003-05-09 | 2004-11-10 | Schering AG | Bone localising radiopharmaceutical and tubulin-interacting compound combinatorial radiotherapy |
| MXPA05012109A (es) * | 2003-05-12 | 2006-02-08 | Bristol Myers Squibb Pharma Co | Compuestos antagonistas del receptor de vitronectina y su uso en la preparacion de radiofarmaceuticos. |
| EP3101012A1 (en) | 2015-06-04 | 2016-12-07 | Bayer Pharma Aktiengesellschaft | New gadolinium chelate compounds for use in magnetic resonance imaging |
| WO2018096082A1 (en) | 2016-11-28 | 2018-05-31 | Bayer Pharma Aktiengesellschaft | High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging |
| US11090395B2 (en) * | 2018-09-14 | 2021-08-17 | SeeCure Taiwan Co., Ltd. | Composition for cross talk between estrogen receptors and cannabinoid receptors |
| AU2019382881B2 (en) | 2018-11-23 | 2025-06-12 | Bayer Aktiengesellschaft | Formulation of contrast media and process of preparation thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE342262T1 (de) * | 1996-11-27 | 2006-11-15 | Bristol Myers Squibb Pharma Co | Neue integrin rezeptor antagonisten |
| US6120995A (en) * | 1997-08-07 | 2000-09-19 | Thomas Jefferson University | Compositions that specifically bind to colorectal cancer cells and methods of using the same |
| US6093382A (en) * | 1998-05-16 | 2000-07-25 | Bracco Research Usa Inc. | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications |
| CA2349501A1 (en) * | 1998-12-18 | 2000-06-22 | Du Pont Pharmaceuticals Company | Quinolone vitronectin receptor antagonist pharmaceuticals |
| EP1311302A2 (en) * | 2000-06-21 | 2003-05-21 | Bristol-Myers Squibb Pharma Company | Pharmaceuticals for the imaging of angiogenic disorders |
| CA2412849A1 (en) * | 2000-06-21 | 2001-12-27 | Bristol-Myers Squibb Pharma Company | Vitronectin receptor antagonist pharmaceuticals for use in combination therapy |
| AU7002501A (en) * | 2000-06-21 | 2002-01-02 | Du Pont Pharm Co | Vitronectin receptor antagonist pharmaceuticals for use in combination therapy |
| US20020122768A1 (en) * | 2000-07-06 | 2002-09-05 | Shuang Liu | Stable radiopharmaceutical compositions and methods for preparation thereof |
-
2001
- 2001-06-21 MX MXPA02012750A patent/MXPA02012750A/es not_active Application Discontinuation
- 2001-06-21 CN CNA018144306A patent/CN1582166A/zh active Pending
- 2001-06-21 AU AU7296501A patent/AU7296501A/xx active Pending
- 2001-06-21 WO PCT/US2001/019793 patent/WO2001097848A2/en not_active Ceased
- 2001-06-21 CA CA2412854A patent/CA2412854C/en not_active Expired - Fee Related
- 2001-06-21 NZ NZ522925A patent/NZ522925A/en unknown
- 2001-06-21 AT AT01952180T patent/ATE414541T1/de not_active IP Right Cessation
- 2001-06-21 BR BRPI0111880-3A patent/BR0111880A/pt not_active IP Right Cessation
- 2001-06-21 AU AU2001272965A patent/AU2001272965C1/en not_active Ceased
- 2001-06-21 IL IL15294101A patent/IL152941A0/xx unknown
- 2001-06-21 DE DE60136632T patent/DE60136632D1/de not_active Expired - Lifetime
- 2001-06-21 JP JP2002503332A patent/JP2004521066A/ja active Pending
- 2001-06-21 EP EP01952180A patent/EP1307226B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001097848A2 (en) | 2001-12-27 |
| EP1307226B1 (en) | 2008-11-19 |
| IL152941A0 (en) | 2003-06-24 |
| CN1582166A (zh) | 2005-02-16 |
| NZ522925A (en) | 2006-08-31 |
| BR0111880A (pt) | 2006-04-25 |
| AU2001272965C1 (en) | 2006-06-29 |
| DE60136632D1 (de) | 2009-01-02 |
| WO2001097848A3 (en) | 2003-03-13 |
| JP2004521066A (ja) | 2004-07-15 |
| CA2412854C (en) | 2010-08-17 |
| ATE414541T1 (de) | 2008-12-15 |
| AU7296501A (en) | 2002-01-02 |
| EP1307226A2 (en) | 2003-05-07 |
| CA2412854A1 (en) | 2001-12-27 |
| AU2001272965B2 (en) | 2005-11-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |