[go: up one dir, main page]

MXPA02012190A - N-(ciclopropilmetil) azacicloalcanos, composiciones que los contienen y metodos para su preparacion. - Google Patents

N-(ciclopropilmetil) azacicloalcanos, composiciones que los contienen y metodos para su preparacion.

Info

Publication number
MXPA02012190A
MXPA02012190A MXPA02012190A MXPA02012190A MXPA02012190A MX PA02012190 A MXPA02012190 A MX PA02012190A MX PA02012190 A MXPA02012190 A MX PA02012190A MX PA02012190 A MXPA02012190 A MX PA02012190A MX PA02012190 A MXPA02012190 A MX PA02012190A
Authority
MX
Mexico
Prior art keywords
azacycloalkanes
cyclopropylmethyl
preparation
methods
compositions containing
Prior art date
Application number
MXPA02012190A
Other languages
English (en)
Inventor
Jacobelli Henry
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of MXPA02012190A publication Critical patent/MXPA02012190A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La presente invencion se refiere a N-(ciclopropilmetil)azacicloalcanos de la siguiente formula (I): (ver formula) en la cual, independientemente, R1 es hidrogeno o halogeno, R2 es hidrogeno o halogeno y X es metileno o etileno, sus sales, las composiciones farmaceuticas que los contienen, su uso como medicamentos antidiarreicos y los metodos para su preparacion.
MXPA02012190A 2001-12-21 2002-12-09 N-(ciclopropilmetil) azacicloalcanos, composiciones que los contienen y metodos para su preparacion. MXPA02012190A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0116785A FR2833945B1 (fr) 2001-12-21 2001-12-21 N-cyclopropylmethyl-azacycloalcanes, compositions les contenant et procedes de preparation

Publications (1)

Publication Number Publication Date
MXPA02012190A true MXPA02012190A (es) 2004-10-29

Family

ID=8870932

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02012190A MXPA02012190A (es) 2001-12-21 2002-12-09 N-(ciclopropilmetil) azacicloalcanos, composiciones que los contienen y metodos para su preparacion.

Country Status (7)

Country Link
US (1) US6787563B2 (es)
EP (1) EP1321461A1 (es)
JP (1) JP2003238530A (es)
BR (1) BR0205410A (es)
CA (1) CA2414905A1 (es)
FR (1) FR2833945B1 (es)
MX (1) MXPA02012190A (es)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05503517A (ja) * 1989-12-18 1993-06-10 バージニア・コモンウェルス・ユニバーシティ シグマレセプターリガンド及びその用途
US5849760A (en) * 1993-12-09 1998-12-15 Institut De Recherche Jouveinal 2-(arylalkenyl)azacycloalkane derivatives as ligands for sigma receptors
FR2760454B1 (fr) * 1997-03-05 1999-04-30 Jouveinal Inst Rech (r) n-(1-cyclopropylmethyl-pyrrolidine-2ylmethyl)-benzamide et son utilite comme antidiarrheique
FR2760455B1 (fr) * 1997-03-05 1999-04-16 Jouveinal Inst Rech (-)e-2-(3,4-dichloro-cinnamyl)-1-cyclopropylmethyl- piperidine, son utilite antidiarrheique

Also Published As

Publication number Publication date
JP2003238530A (ja) 2003-08-27
EP1321461A1 (en) 2003-06-25
CA2414905A1 (en) 2003-06-21
US6787563B2 (en) 2004-09-07
FR2833945A1 (fr) 2003-06-27
BR0205410A (pt) 2004-07-20
US20030139448A1 (en) 2003-07-24
FR2833945B1 (fr) 2004-03-12

Similar Documents

Publication Publication Date Title
NO20074657L (no) Nitrogenholdige aromatiske ringforbindelser
AP1614A (en) New heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-bacterial agents.
AP1739A (en) Azaindoles
GB0114286D0 (en) Nucleoside Derivatives
MXPA02012033A (es) Derivados de 2-aminocarbonil-9h-purina.
MY137535A (en) New pyrrolidinium derivatives
GB9914486D0 (en) Medicaments
MXPA05010137A (es) Derivados de tetrahidroisoquinolil acetamida para usarse como antagonistas del receptor de orexina.
MY139303A (en) Novel aromatic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof
JO2353B1 (en) New derivatives of mixed-ring fluoroglycosides and drugs containing these compounds and their use
PL358281A1 (en) Novel compounds
AU2003228770A8 (en) Substituted pyrazolopyrimidines
MXPA04003192A (es) Sales de acido succinico de 5, 7, 14-triazatetraciclo ?10.3.1.02,11.04,9? -hexadeca-2(11), 3, 5, 7, 9-pentaeno y composiciones farmacetucias de las mismas.
MX2009005507A (es) Derivados de espiro-piperidina.
MXPA03010766A (es) Nuevos compuestos y composiciones como inhibicores de las catepsinas.
WO2003066594A3 (de) 3-alkanoylamino-propionsäure-derivate als inhibitoren des integrins avss6
GB0120461D0 (en) Novel compounds
IL174678A0 (en) Arylindenophyridines and arylindenophyrimidines and their use as adenosine a2a receptor antagonist
TW200714598A (en) Urea derivatives, methods for their manufacture, and uses therefor
DE60201074D1 (en) Pyrazolopyridinderivate
YU34604A (sh) Oligopeptidi kao inhibitori katepsina s i kompozicije koje ih sadrže
MXPA02012190A (es) N-(ciclopropilmetil) azacicloalcanos, composiciones que los contienen y metodos para su preparacion.
NO20041761L (no) Nye hydroksyalkylindolokarbazolforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem
CA2426221A1 (en) New neurokinin antagonists, processes for preparing them and pharmaceutical compositions containing these compounds
UY26971A1 (es) Nuevos antagonistas de neuroquinina, procedimiento para su preparación y composiciones farmacéuticas que contienen estos compuestos