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MXPA02011415A - Particulas quimericas similares a arterivirus. - Google Patents

Particulas quimericas similares a arterivirus.

Info

Publication number
MXPA02011415A
MXPA02011415A MXPA02011415A MXPA02011415A MXPA02011415A MX PA02011415 A MXPA02011415 A MX PA02011415A MX PA02011415 A MXPA02011415 A MX PA02011415A MX PA02011415 A MXPA02011415 A MX PA02011415A MX PA02011415 A MXPA02011415 A MX PA02011415A
Authority
MX
Mexico
Prior art keywords
arterivirus
particles
structural protein
chimeric
arteriviruses
Prior art date
Application number
MXPA02011415A
Other languages
English (en)
Inventor
Monique Helene Verheije
Original Assignee
Id Lelystad Inst Dierhouderij
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Id Lelystad Inst Dierhouderij filed Critical Id Lelystad Inst Dierhouderij
Publication of MXPA02011415A publication Critical patent/MXPA02011415A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10023—Virus like particles [VLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10061—Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La invencion se refiere al campo de Arterivirus y a vacunas dirigidas contra infecciones causadas por estos virus. La invencion proporciona una particula similar a Arterivirus que comprende al menos una primera proteina estructural derivada de un primer Arterivirus y una segunda proteina estructural, en donde la segunda proteina estructural al menos parcialmente no se deriva del primer Arterivirus.
MXPA02011415A 2000-05-19 2001-05-21 Particulas quimericas similares a arterivirus. MXPA02011415A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00201780A EP1156111A1 (en) 2000-05-19 2000-05-19 Chimeric arterivirus-like particles
PCT/NL2001/000382 WO2001090363A1 (en) 2000-05-19 2001-05-21 Chimeric arterivirus-like particles

Publications (1)

Publication Number Publication Date
MXPA02011415A true MXPA02011415A (es) 2004-02-26

Family

ID=8171523

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02011415A MXPA02011415A (es) 2000-05-19 2001-05-21 Particulas quimericas similares a arterivirus.

Country Status (14)

Country Link
US (1) US7122347B2 (es)
EP (2) EP1156111A1 (es)
JP (1) JP4875274B2 (es)
KR (1) KR100916883B1 (es)
AT (1) ATE426026T1 (es)
AU (1) AU2001258938A1 (es)
CA (1) CA2409209C (es)
CY (1) CY1109141T1 (es)
DE (1) DE60138014D1 (es)
DK (1) DK1283887T3 (es)
ES (1) ES2322237T3 (es)
MX (1) MXPA02011415A (es)
PT (1) PT1283887E (es)
WO (1) WO2001090363A1 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
EP1157121B1 (en) 1999-03-08 2013-04-24 Boehringer Ingelheim Vetmedica GmbH Prrsv replicon
JP4778620B2 (ja) 1999-04-22 2011-09-21 ユナイテッド ステイツ デパートメント オブ アグリカルチャー 分離株ｊａ−１４２に基づく、豚繁殖・呼吸障害症候群ワクチン
KR20030082960A (ko) * 2001-03-09 2003-10-23 베링거잉겔하임베트메디카게엠베하 Ｐｒｒｓ 바이러스의 약독화된 생균 균주
EP1438969A1 (en) * 2003-01-14 2004-07-21 Universiteit Utrecht Arterivirus marker vaccine
EP1781327A4 (en) 2004-06-18 2009-02-25 Univ Minnesota IDENTIFICATION OF VIRAL INFECTED AND VACCINATED ORGANISMS
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
PL2369001T3 (pl) 2005-06-24 2017-06-30 Regents Of The University Of Minnesota Wirusy PRRS, ich klony zakaźne, mutanty i sposoby stosowania
US7951384B2 (en) * 2005-08-05 2011-05-31 University Of Massachusetts Virus-like particles as vaccines for paramyxovirus
US9216212B2 (en) 2005-08-05 2015-12-22 University Of Massachusetts Virus-like particles as vaccines for paramyxovirus
WO2007064742A2 (en) 2005-11-29 2007-06-07 Iowa State University Research Foundation, Inc. Identification of protective antigenic determinants of porcine reproductive and respiratory syndrome virus (prrsv) and uses thereof
TW201605471A (zh) * 2007-04-30 2016-02-16 Ｍｊ生物股份有限公司 豬繁殖與呼吸道症候群病毒（ｐｒｒｓｖ）ｇｐ５爲主之組成物及方法
US7666585B2 (en) * 2007-06-15 2010-02-23 Protatek International, Inc. Construction of chimera PRRSV, compositions and vaccine preparations
AU2009285843B2 (en) * 2008-08-25 2014-07-17 Boehringer Ingelheim Vetmedica Inc Vaccine against Highly Pathogenic Porcine Reproductive and Respiratory Syndrome (HP PRRS)
US8580270B2 (en) * 2008-09-30 2013-11-12 University Of Massachusetts Respiratory synctial virus (RSV) sequences for protein expression and vaccines
EP2230246A1 (en) * 2009-03-19 2010-09-22 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Arterivirus glycoprotein 5 virus-like particles
TWI627281B (zh) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
UA117272C2 (uk) 2011-02-17 2018-07-10 Бьорінгер Інгельхайм Ветмедіка Гмбх Новий європейський штам prrsv
CN103370077B (zh) 2011-02-17 2016-10-26 贝林格尔.英格海姆维特梅迪卡有限公司 猪繁殖与呼吸综合征病毒的商业化规模生产方法
WO2013017568A1 (en) 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
CN102908617A (zh) * 2011-08-04 2013-02-06 广州格拉姆生物科技有限公司 一种猪繁殖与呼吸综合症病毒m蛋白与cd40l融合疫苗及制备方法
CN105073130A (zh) 2013-03-15 2015-11-18 勃林格殷格翰动物保健公司 猪生殖与呼吸综合征病毒、组合物、疫苗及使用方法
MX2020010248A (es) 2013-12-20 2020-10-16 Boehringer Ingelheim Vetmedica Gmbh Variante del virus prrs, clon de adnc del virus europeo y sus usos.
WO2016021276A1 (ja) 2014-08-08 2016-02-11 出光興産株式会社 豚繁殖・呼吸障害症候群防除剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2102971B1 (es) * 1996-01-25 1998-03-01 Hipra Lab Sa Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion.
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
AU7960598A (en) * 1997-06-05 1998-12-21 Origen, Inc. Recombinant porcine reproductive and respiratory syndrome virus (prrsv) for use as a vaccine
EP1157121B1 (en) * 1999-03-08 2013-04-24 Boehringer Ingelheim Vetmedica GmbH Prrsv replicon

Also Published As

Publication number Publication date
EP1283887A1 (en) 2003-02-19
KR100916883B1 (ko) 2009-09-09
JP4875274B2 (ja) 2012-02-15
EP1283887B1 (en) 2009-03-18
KR20030026931A (ko) 2003-04-03
CY1109141T1 (el) 2014-07-02
CA2409209A1 (en) 2001-11-29
US20030161845A1 (en) 2003-08-28
ATE426026T1 (de) 2009-04-15
CA2409209C (en) 2011-08-09
EP1156111A1 (en) 2001-11-21
WO2001090363A1 (en) 2001-11-29
ES2322237T3 (es) 2009-06-18
DE60138014D1 (de) 2009-04-30
JP2004506411A (ja) 2004-03-04
DK1283887T3 (da) 2009-06-22
US7122347B2 (en) 2006-10-17
AU2001258938A1 (en) 2001-12-03
PT1283887E (pt) 2009-03-31

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