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MXPA02011481A - Derivados de disulfuro que son utiles para el tratamiento de enfermedades alergicas. - Google Patents

Derivados de disulfuro que son utiles para el tratamiento de enfermedades alergicas.

Info

Publication number
MXPA02011481A
MXPA02011481A MXPA02011481A MXPA02011481A MXPA02011481A MX PA02011481 A MXPA02011481 A MX PA02011481A MX PA02011481 A MXPA02011481 A MX PA02011481A MX PA02011481 A MXPA02011481 A MX PA02011481A MX PA02011481 A MXPA02011481 A MX PA02011481A
Authority
MX
Mexico
Prior art keywords
disulfide derivatives
allergic diseases
treating allergic
derivatives useful
treating
Prior art date
Application number
MXPA02011481A
Other languages
English (en)
Inventor
Mark R Hellberg
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of MXPA02011481A publication Critical patent/MXPA02011481A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Derivados de disulfuro de difenilo de la formula (I) en donde X es -NHC(=O)NH-R y R es como se define en las reivindicaciones, son °tiles para prevenir o para tratar las enfermedades alérgicas de los ojos, nariz, piel, oidos, tracto gastrointestinal, vias respiratorias o pulmon, y para prevenir o tratar las manifestaciones de mastocitosis sistémica; los derivados de disulfuro actuan como estabilizadores de mastocitos.
MXPA02011481A 2000-05-19 2001-04-25 Derivados de disulfuro que son utiles para el tratamiento de enfermedades alergicas. MXPA02011481A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20582700P 2000-05-19 2000-05-19
PCT/US2001/013331 WO2001090060A1 (en) 2000-05-19 2001-04-25 Disulfide derivatives useful for treating allergic diseases

Publications (1)

Publication Number Publication Date
MXPA02011481A true MXPA02011481A (es) 2003-06-06

Family

ID=22763799

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02011481A MXPA02011481A (es) 2000-05-19 2001-04-25 Derivados de disulfuro que son utiles para el tratamiento de enfermedades alergicas.

Country Status (19)

Country Link
US (3) US6492552B2 (es)
EP (1) EP1282599B1 (es)
JP (1) JP2003534318A (es)
KR (1) KR20030007589A (es)
CN (2) CN1241912C (es)
AR (1) AR028566A1 (es)
AT (1) ATE330938T1 (es)
AU (2) AU5567501A (es)
BR (1) BR0110943A (es)
CA (1) CA2407964A1 (es)
CY (1) CY1105164T1 (es)
DE (1) DE60120961T2 (es)
DK (1) DK1282599T3 (es)
ES (1) ES2261402T3 (es)
MX (1) MXPA02011481A (es)
PL (1) PL365457A1 (es)
PT (1) PT1282599E (es)
WO (1) WO2001090060A1 (es)
ZA (1) ZA200208840B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2222370T3 (es) * 2000-05-19 2005-02-01 Alcon Inc. Derivados de disulfuro de anilina para tratar enfermedades alergicas.
US7645903B2 (en) 2002-10-31 2010-01-12 Ge Healthcare Bio-Sciences Ab Use of urea variants as affinity ligands
KR20070024618A (ko) * 2004-06-28 2007-03-02 알콘, 인코퍼레이티드 알레르기성 질환 치료용 국소 제제
EP1841808B1 (en) * 2004-12-22 2009-01-21 California Institute Of Technology Degradable p0lymers and methods of preparation thereof
US9993529B2 (en) 2011-06-17 2018-06-12 Halozyme, Inc. Stable formulations of a hyaluronan-degrading enzyme
CN105797140B (zh) * 2011-06-17 2020-08-11 哈洛齐梅公司 乙酰透明质酸降解酶的稳定制剂
FR3057264B1 (fr) * 2016-10-12 2020-05-29 Arkema France Composes porteurs de groupes associatifs azotes
CN108586299B (zh) * 2018-06-06 2020-06-16 北京化工大学 一种可引发、聚合及降低体积收缩的芳香二硫化合物的制备方法及用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1232787A (es) 1967-08-08 1971-05-19
US3663616A (en) 1969-10-13 1972-05-16 Sherwin Williams Co Bis(2-carbamylphenyl)disulfides
EP0006227B1 (en) * 1978-06-16 1984-12-27 Kyowa Hakko Kogyo Co., Ltd Antithrombotic pharmaceutical preparation containing 2,2'-dithiobis benzamide derivatives and new 2,2'-dithiobis benzamide derivatives
GB8520662D0 (en) 1985-08-17 1985-09-25 Wellcome Found Tricyclic aromatic compounds
US4923892A (en) 1985-08-17 1990-05-08 Burroughs Wellcome Co. Tricyclic aromatic compounds
JPS6310784A (ja) 1986-03-03 1988-01-18 Kyowa Hakko Kogyo Co Ltd 抗アレルギー剤
GB9020933D0 (en) 1990-09-26 1990-11-07 Ici Plc Compound,preparation and use
US5859017A (en) 1994-04-01 1999-01-12 Cell Therapeutics, Inc. Method for inhibiting mast cell and basophil activation
US5734081A (en) 1994-08-05 1998-03-31 Warner-Lambert Company Arylthio compounds
US5463122A (en) 1994-08-05 1995-10-31 Warner-Lambert Company Arylthio compounds
US6001555A (en) 1994-09-23 1999-12-14 The United States Of America As Represented By The Department Of Health And Human Services Method for identifying and using compounds that inactivate HIV-1 and other retroviruses by attacking highly conserved zinc fingers in the viral nucleocapsid protein
JPH095926A (ja) 1995-04-18 1997-01-10 Fuji Photo Film Co Ltd 熱現像感光材料
US5641805A (en) 1995-06-06 1997-06-24 Alcon Laboratories, Inc. Topical ophthalmic formulations for treating allergic eye diseases
AU2458697A (en) 1996-04-18 1997-11-07 Alcon Laboratories, Inc. Calcium channel blockers as human conjunctival mast cell degranulation inhibitors for treating ocular allergic conditions
JP2894445B2 (ja) 1997-02-12 1999-05-24 日本たばこ産業株式会社 Ｃｅｔｐ活性阻害剤として有効な化合物
JP3940201B2 (ja) 1997-05-20 2007-07-04 大塚製薬株式会社 ３，３’−ジチオジベンゾヒドロキサム酸

Also Published As

Publication number Publication date
DK1282599T3 (da) 2006-07-31
CA2407964A1 (en) 2001-11-29
AU2001255675B2 (en) 2005-04-14
WO2001090060A1 (en) 2001-11-29
ZA200208840B (en) 2003-12-02
US6500864B1 (en) 2002-12-31
US20020058709A1 (en) 2002-05-16
PL365457A1 (en) 2005-01-10
ATE330938T1 (de) 2006-07-15
US20020193633A1 (en) 2002-12-19
EP1282599A1 (en) 2003-02-12
HK1050185A1 (en) 2003-06-13
CN1175807C (zh) 2004-11-17
BR0110943A (pt) 2004-01-06
CN1429209A (zh) 2003-07-09
AR028566A1 (es) 2003-05-14
US20020193634A1 (en) 2002-12-19
AU5567501A (en) 2001-12-03
ES2261402T3 (es) 2006-11-16
CN1616422A (zh) 2005-05-18
DE60120961T2 (de) 2006-11-16
KR20030007589A (ko) 2003-01-23
EP1282599B1 (en) 2006-06-21
JP2003534318A (ja) 2003-11-18
CY1105164T1 (el) 2010-03-03
CN1241912C (zh) 2006-02-15
PT1282599E (pt) 2006-08-31
US6506802B2 (en) 2003-01-14
US6492552B2 (en) 2002-12-10
DE60120961D1 (de) 2006-08-03

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