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MXPA02010263A - Proceso para preparar lipido ii. - Google Patents

Proceso para preparar lipido ii.

Info

Publication number
MXPA02010263A
MXPA02010263A MXPA02010263A MXPA02010263A MXPA02010263A MX PA02010263 A MXPA02010263 A MX PA02010263A MX PA02010263 A MXPA02010263 A MX PA02010263A MX PA02010263 A MXPA02010263 A MX PA02010263A MX PA02010263 A MXPA02010263 A MX PA02010263A
Authority
MX
Mexico
Prior art keywords
cell wall
bacterial cell
wall biosynthesis
lipid
preparing lipid
Prior art date
Application number
MXPA02010263A
Other languages
English (en)
Inventor
Ebrahimi Mohammad Sadegh Zia
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MXPA02010263A publication Critical patent/MXPA02010263A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/003—Peptides being substituted by heterocyclic radicals, e.g. bleomycin, phleomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Se describe un proceso para preparar un sustrato para las enzimas de transglucosilasa de la biosintesis de pared de celulas bacterianas. La sintesis quimica vuelve disponible una fuente sostenible y sustancialmente pura de suministro de lipido II, que incluye analogos de los mismos, que se puede utilizar en la identificacion de agentes terapeuticos nuevos capaces de interrumpir etapas en la biosintesis de la pared de celulas bacterianas.
MXPA02010263A 2000-04-18 2001-04-18 Proceso para preparar lipido ii. MXPA02010263A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19800000P 2000-04-18 2000-04-18
PCT/US2001/012637 WO2001079242A2 (en) 2000-04-18 2001-04-18 Process for preparing lipid ii and derivatives thereof

Publications (1)

Publication Number Publication Date
MXPA02010263A true MXPA02010263A (es) 2004-08-12

Family

ID=22731586

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02010263A MXPA02010263A (es) 2000-04-18 2001-04-18 Proceso para preparar lipido ii.

Country Status (11)

Country Link
US (1) US7169919B2 (es)
EP (1) EP1276746A2 (es)
JP (1) JP2004501085A (es)
KR (1) KR20030011306A (es)
AU (1) AU2001255460A1 (es)
BR (1) BR0109968A (es)
CA (1) CA2406952A1 (es)
HU (1) HUP0303579A3 (es)
IL (1) IL152157A0 (es)
MX (1) MXPA02010263A (es)
WO (1) WO2001079242A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002085929A1 (en) * 2001-04-18 2002-10-31 Eli Lilly And Company Process for preparing lipid ii
EP1275731A1 (en) * 2001-07-09 2003-01-15 Universiteit Utrecht Holding B.V. Method for preparing lipid II and use of the lipid II thus obtained
EP1494687A2 (en) * 2002-03-08 2005-01-12 Eli Lilly And Company Immunomodulatory polymeric antigens for treating inflammatory pathogies
WO2005035588A1 (en) * 2003-09-17 2005-04-21 Eli Lilly And Company Synthetic polysaccharide antigens for immunological intervention in disease
EP2684865A1 (en) * 2012-07-13 2014-01-15 Heidelberg Pharma GmbH Methods for synthesizing amatoxin building block and amatoxins
CN104610405B (zh) * 2015-02-10 2017-03-01 山东大学 一种6,6’‑双(2,3‑二甲氧基苯甲酰基)‑α,α‑D‑海藻糖及其中间体的制备方法
US10717703B2 (en) 2017-08-21 2020-07-21 Celgene Corporation Processes for the preparation of (S)-tert-butyl 4,5-diamino-5-oxopentanoate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU727647A1 (ru) 1977-11-02 1980-04-15 Институт биоорганической химии им.М.М.Шемякина Гликопептиды,обладающие противоопухолевой активностью и способ их получени
US5141674A (en) * 1984-03-08 1992-08-25 Phares Pharmaceutical Research N.V. Methods of preparing pro-liposome dispersions and aerosols
EP0615522B1 (en) 1991-11-19 1999-09-22 Peptech (Uk) Limited Muramyl compounds for treatment of septic shock

Also Published As

Publication number Publication date
CA2406952A1 (en) 2001-10-25
BR0109968A (pt) 2003-05-27
JP2004501085A (ja) 2004-01-15
US20030027980A1 (en) 2003-02-06
EP1276746A2 (en) 2003-01-22
AU2001255460A1 (en) 2001-10-30
IL152157A0 (en) 2003-05-29
WO2001079242A2 (en) 2001-10-25
US7169919B2 (en) 2007-01-30
HUP0303579A2 (hu) 2004-03-01
WO2001079242A3 (en) 2002-06-06
KR20030011306A (ko) 2003-02-07
HUP0303579A3 (en) 2004-03-29

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal