MXPA02010184A - Formulaciones topicas para el suministro transdermico de niacina y metodos para tratar hiperlipidemia. - Google Patents
Formulaciones topicas para el suministro transdermico de niacina y metodos para tratar hiperlipidemia.Info
- Publication number
- MXPA02010184A MXPA02010184A MXPA02010184A MXPA02010184A MXPA02010184A MX PA02010184 A MXPA02010184 A MX PA02010184A MX PA02010184 A MXPA02010184 A MX PA02010184A MX PA02010184 A MXPA02010184 A MX PA02010184A MX PA02010184 A MXPA02010184 A MX PA02010184A
- Authority
- MX
- Mexico
- Prior art keywords
- niacin
- methods
- transdermal delivery
- topical formulations
- treating hyperlipidemia
- Prior art date
Links
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 title abstract 3
- 229960003512 nicotinic acid Drugs 0.000 title abstract 3
- 235000001968 nicotinic acid Nutrition 0.000 title abstract 3
- 239000011664 nicotinic acid Substances 0.000 title abstract 3
- 208000031226 Hyperlipidaemia Diseases 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000012049 topical pharmaceutical composition Substances 0.000 title 1
- 230000037317 transdermal delivery Effects 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La niacina y profarmacos de niacina se administran topicamentecomo formulaciones o dispositivos adecuados para mejorar los perfiles deIipidos de sujetos, de preferencia humanos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19762100P | 2000-04-14 | 2000-04-14 | |
| PCT/US2001/012356 WO2001078727A1 (en) | 2000-04-14 | 2001-04-16 | Topical formulations for the transdermal delivery of niacin and methods of treating hyperlipidemia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA02010184A true MXPA02010184A (es) | 2004-08-19 |
Family
ID=22730106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA02010184A MXPA02010184A (es) | 2000-04-14 | 2001-04-16 | Formulaciones topicas para el suministro transdermico de niacina y metodos para tratar hiperlipidemia. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6677361B2 (es) |
| EP (1) | EP1274429B1 (es) |
| JP (1) | JP4156841B2 (es) |
| CN (1) | CN1430513B (es) |
| AT (1) | ATE395061T1 (es) |
| AU (2) | AU2001257063B2 (es) |
| CA (1) | CA2441461C (es) |
| DE (1) | DE60134002D1 (es) |
| DK (1) | DK1274429T3 (es) |
| ES (1) | ES2302732T3 (es) |
| MX (1) | MXPA02010184A (es) |
| PT (1) | PT1274429E (es) |
| WO (1) | WO2001078727A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6464992B2 (en) * | 2000-04-14 | 2002-10-15 | University Of Kentucky Research Foundation | Topical micronutrient delivery system and uses thereof |
| US20040081672A1 (en) * | 2002-10-25 | 2004-04-29 | Gupta Shyam K. | Niacinamide, niacin, and niacin esters based delivery systems for treating topical disorders of skin and skin aging |
| US20040191278A1 (en) * | 2003-03-31 | 2004-09-30 | Christensen Flemming Kjaergaar | Topical agent for application to the skin prior to luminous treatment |
| US20040254202A1 (en) * | 2003-06-13 | 2004-12-16 | The Procter & Gamble Company | Method of promoting sleep using topical administration of vasoactive agents |
| US20050267091A1 (en) * | 2004-05-25 | 2005-12-01 | Roger Berlin | Compositions containing policosanol and niacin and/or niacin derivatives and their pharmaceutical uses |
| CN101742916B (zh) * | 2007-02-28 | 2015-08-19 | 肯塔基大学研究基金会 | 减轻视黄酸治疗副作用和/或改进疗效而不干扰疗效的方法 |
| WO2008126088A2 (en) * | 2007-04-15 | 2008-10-23 | Oron Zachar | Anti-pyretic vasodilators |
| CN102532114B (zh) * | 2011-12-19 | 2016-08-03 | 中山大学 | 烟酸衍生物,其制备方法及其药物组合物 |
| EP3016655A4 (en) | 2013-05-09 | 2017-04-12 | Zeenar Enterprises Pty Ltd | Niacin formulation |
| MX2016016071A (es) | 2014-06-06 | 2017-07-11 | Glaxosmithkline Intellectual Property (No 2) Ltd | Analogos de ribosido de nicotinamida y composiciones farmaceuticas y usos de los mismos. |
| WO2019046735A1 (en) * | 2017-08-31 | 2019-03-07 | Lonza Inc. | HEALTH PROMOTING COMPOSITION AND METHODS OF USING COMPLEMENT-RELATED APPLICATIONS |
| EP3727315B1 (en) | 2017-12-18 | 2021-10-13 | Unilever Global IP Limited | A topical composition comprising n-cyclopropyl nicotinamide |
| US20200316050A1 (en) * | 2017-12-18 | 2020-10-08 | Conopco, Inc., D/B/A Unilever | A topical composition based on niacinamide derivative |
| EP3873415A1 (en) | 2018-11-02 | 2021-09-08 | Unilever Global Ip Limited | Bioenergetic nicotinic acid glycerol esters, compositions and methods of using same |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1046055B (de) * | 1956-06-18 | 1958-12-11 | Ernst Schneider Dipl Chem Dr | Verfahren zur Herstellung eines Esters mehrfach ungesaettigter hoehermolekularer Fettsaeuren |
| EP0182635B1 (en) * | 1984-11-15 | 1989-05-31 | Nitto Denko Corporation | Composition for percutaneous administration |
| GB2210789A (en) * | 1987-10-10 | 1989-06-21 | Morrison Dr Ian Donald | Topical application for skin care |
| EP0346490B1 (en) * | 1987-12-24 | 1993-04-07 | Fujisawa Pharmaceutical Co., Ltd. | Hair growth promoting agent |
| EP0643965B1 (en) * | 1993-09-20 | 2013-05-08 | Abbott Laboratories | Nicotinic acid compositions for treating hyperlipidemia |
| US5496827A (en) * | 1994-07-15 | 1996-03-05 | Patrick; Jay | Compositions for the transdermal delivery of nutrients |
| EP0821587A4 (en) * | 1995-04-19 | 1999-05-19 | Lipoprotein Technologies Inc | COMPOSITIONS, KITS AND METHODS FOR ADMINISTERING ANTILIPEMICS AND MEDICINES AGAINST PLATELET AGGREGATION |
| KR19990008242A (ko) * | 1995-05-01 | 1999-01-25 | 까뜨리오나 프란세스 마르 | 니코틴산 에스테르 및 니코틴산 에스테르를 함유한 약품 |
| GB9610971D0 (en) * | 1996-05-29 | 1996-07-31 | Scotia Holdings Plc | A diagnostic test for use in schizophrenia |
| WO1998052927A1 (en) * | 1997-05-19 | 1998-11-26 | Rosemarie Scivoletto | Composition for treating skin conditions |
| DK1143954T3 (da) * | 1998-12-01 | 2004-12-20 | Univ Kentucky Res Found | Anvendelse af nicotinsyrederivater til behandling af DNA-skade i hudceller |
| US6464992B2 (en) * | 2000-04-14 | 2002-10-15 | University Of Kentucky Research Foundation | Topical micronutrient delivery system and uses thereof |
-
2001
- 2001-04-16 AU AU2001257063A patent/AU2001257063B2/en not_active Ceased
- 2001-04-16 DE DE60134002T patent/DE60134002D1/de not_active Expired - Lifetime
- 2001-04-16 WO PCT/US2001/012356 patent/WO2001078727A1/en not_active Ceased
- 2001-04-16 CN CN018100678A patent/CN1430513B/zh not_active Expired - Fee Related
- 2001-04-16 US US09/836,843 patent/US6677361B2/en not_active Expired - Lifetime
- 2001-04-16 CA CA002441461A patent/CA2441461C/en not_active Expired - Lifetime
- 2001-04-16 EP EP01930535A patent/EP1274429B1/en not_active Expired - Lifetime
- 2001-04-16 JP JP2001576027A patent/JP4156841B2/ja not_active Expired - Fee Related
- 2001-04-16 MX MXPA02010184A patent/MXPA02010184A/es active IP Right Grant
- 2001-04-16 ES ES01930535T patent/ES2302732T3/es not_active Expired - Lifetime
- 2001-04-16 DK DK01930535T patent/DK1274429T3/da active
- 2001-04-16 PT PT01930535T patent/PT1274429E/pt unknown
- 2001-04-16 AU AU5706301A patent/AU5706301A/xx active Pending
- 2001-04-16 AT AT01930535T patent/ATE395061T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| CN1430513A (zh) | 2003-07-16 |
| WO2001078727A8 (en) | 2003-11-27 |
| JP4156841B2 (ja) | 2008-09-24 |
| CA2441461A1 (en) | 2001-10-25 |
| AU5706301A (en) | 2001-10-30 |
| US6677361B2 (en) | 2004-01-13 |
| US20010049382A1 (en) | 2001-12-06 |
| EP1274429A4 (en) | 2006-03-01 |
| EP1274429B1 (en) | 2008-05-14 |
| AU2001257063B2 (en) | 2005-04-28 |
| CA2441461C (en) | 2007-07-10 |
| EP1274429A1 (en) | 2003-01-15 |
| JP2004500428A (ja) | 2004-01-08 |
| CN1430513B (zh) | 2010-12-08 |
| WO2001078727A1 (en) | 2001-10-25 |
| ES2302732T3 (es) | 2008-08-01 |
| DK1274429T3 (da) | 2008-08-25 |
| ATE395061T1 (de) | 2008-05-15 |
| PT1274429E (pt) | 2008-06-17 |
| HK1053607A1 (en) | 2003-10-31 |
| DE60134002D1 (de) | 2008-06-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |