MXPA02003891A - Portador objetivado magnetico, compuesto de hierro y materiales porosos, para la entrega de agentes biologicamente activos. - Google Patents
Portador objetivado magnetico, compuesto de hierro y materiales porosos, para la entrega de agentes biologicamente activos.Info
- Publication number
- MXPA02003891A MXPA02003891A MXPA02003891A MXPA02003891A MXPA02003891A MX PA02003891 A MXPA02003891 A MX PA02003891A MX PA02003891 A MXPA02003891 A MX PA02003891A MX PA02003891 A MXPA02003891 A MX PA02003891A MX PA02003891 A MXPA02003891 A MX PA02003891A
- Authority
- MX
- Mexico
- Prior art keywords
- particles
- iron
- ceramic
- biologically active
- composition
- Prior art date
Links
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- 230000009871 nonspecific binding Effects 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- FPLYNRPOIZEADP-UHFFFAOYSA-N octylsilane Chemical compound CCCCCCCC[SiH3] FPLYNRPOIZEADP-UHFFFAOYSA-N 0.000 description 1
- 229940127240 opiate Drugs 0.000 description 1
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 238000003921 particle size analysis Methods 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- PARWUHTVGZSQPD-UHFFFAOYSA-N phenylsilane Chemical compound [SiH3]C1=CC=CC=C1 PARWUHTVGZSQPD-UHFFFAOYSA-N 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 230000008288 physiological mechanism Effects 0.000 description 1
- 239000013612 plasmid Substances 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 108091033319 polynucleotide Proteins 0.000 description 1
- 102000040430 polynucleotide Human genes 0.000 description 1
- 239000002157 polynucleotide Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 229940063238 premarin Drugs 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000651 prodrug Substances 0.000 description 1
- 229940002612 prodrug Drugs 0.000 description 1
- 239000000583 progesterone congener Substances 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 125000001453 quaternary ammonium group Chemical group 0.000 description 1
- MCJGNVYPOGVAJF-UHFFFAOYSA-N quinolin-8-ol Chemical compound C1=CN=C2C(O)=CC=CC2=C1 MCJGNVYPOGVAJF-UHFFFAOYSA-N 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000004043 responsiveness Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000001878 scanning electron micrograph Methods 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 229940125723 sedative agent Drugs 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 229910000077 silane Inorganic materials 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 229930002534 steroid glycoside Natural products 0.000 description 1
- 150000008143 steroidal glycosides Chemical class 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 229960001712 testosterone propionate Drugs 0.000 description 1
- GBNXLQPMFAUCOI-UHFFFAOYSA-H tetracalcium;oxygen(2-);diphosphate Chemical compound [O-2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O GBNXLQPMFAUCOI-UHFFFAOYSA-H 0.000 description 1
- 210000001685 thyroid gland Anatomy 0.000 description 1
- 230000007675 toxicity by organ Effects 0.000 description 1
- 231100000155 toxicity by organ Toxicity 0.000 description 1
- AEGSYIKLTCZUEZ-FZTWWWDYSA-K tri(quinolin-8-yloxy)indigane Chemical compound [111In+3].C1=CN=C2C([O-])=CC=CC2=C1.C1=CN=C2C([O-])=CC=CC2=C1.C1=CN=C2C([O-])=CC=CC2=C1 AEGSYIKLTCZUEZ-FZTWWWDYSA-K 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
- PQDJYEQOELDLCP-UHFFFAOYSA-N trimethylsilane Chemical compound C[SiH](C)C PQDJYEQOELDLCP-UHFFFAOYSA-N 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 229910052882 wollastonite Inorganic materials 0.000 description 1
- 239000010456 wollastonite Substances 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5094—Microcapsules containing magnetic carrier material, e.g. ferrite for drug targeting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6923—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being an inorganic particle, e.g. ceramic particles, silica particles, ferrite or synsorb
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ceramic Engineering (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Materials For Medical Uses (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Paints Or Removers (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16029399P | 1999-10-18 | 1999-10-18 | |
| PCT/US2000/028615 WO2001028587A2 (fr) | 1999-10-18 | 2000-10-13 | Porteurs magnetiques cibles composes de fer et de matieres poreuses pour l'administration ciblee d'agents biologiquement actifs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA02003891A true MXPA02003891A (es) | 2002-12-09 |
Family
ID=22576298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA02003891A MXPA02003891A (es) | 1999-10-18 | 2000-10-13 | Portador objetivado magnetico, compuesto de hierro y materiales porosos, para la entrega de agentes biologicamente activos. |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1221974A2 (fr) |
| JP (3) | JP2003512336A (fr) |
| KR (1) | KR20020064299A (fr) |
| CN (1) | CN1287859C (fr) |
| AU (1) | AU772755B2 (fr) |
| BR (1) | BR0014877A (fr) |
| CA (1) | CA2387925A1 (fr) |
| CZ (1) | CZ293919B6 (fr) |
| DE (1) | DE1221974T1 (fr) |
| ES (1) | ES2182731T1 (fr) |
| HK (1) | HK1045110A1 (fr) |
| IL (1) | IL149004A0 (fr) |
| MX (1) | MXPA02003891A (fr) |
| NZ (1) | NZ518311A (fr) |
| WO (1) | WO2001028587A2 (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9808052D0 (en) | 1998-04-17 | 1998-06-17 | Secr Defence | Implants for administering substances and methods of producing implants |
| CN1879065A (zh) * | 2003-09-12 | 2006-12-13 | 弗尔克斯破产财产公司 | 用于生物活性剂的定位传递的包含磁性成分和生物相容性聚合物的可磁靶向颗粒 |
| JP2007001865A (ja) * | 2003-09-16 | 2007-01-11 | Ltt Bio-Pharma Co Ltd | 脂溶性薬物封入微粒子、その製造法およびそれを含有する製剤 |
| US20080138437A1 (en) * | 2004-02-09 | 2008-06-12 | Shuji Sakuma | Antitumor Agent |
| GB0403856D0 (en) * | 2004-02-20 | 2004-03-24 | Algeta As | Composition |
| BRPI0507824A (pt) * | 2004-02-20 | 2007-07-10 | Algeta As | hidroxiapatita, processo para a preparação de um particulado de hidroxiapatita marcada com radionuclìdeo, composição farmacêutica, uso de hidroxiapatita e de um radionuclìdeo emissor de alfa ou um radionuclìdeo emissor de beta, dispositivo, e, método de tratamento radioquìmico de um ser humano ou de um indivìduo animal não humano necessitando do mesmo |
| JP2006199810A (ja) * | 2005-01-20 | 2006-08-03 | Yokohama National Univ | 複合粒子およびその製造方法 |
| US8293274B2 (en) | 2005-04-06 | 2012-10-23 | Kabushiki Kaisha Sangi | Intestinal absorptive anti-tumor agent |
| CN105476951A (zh) | 2009-05-04 | 2016-04-13 | 普西维达公司 | 多孔硅药物洗脱颗粒 |
| CA2816576C (fr) * | 2010-11-01 | 2020-06-02 | Psivida Us, Inc. | Dispositifs a base de silicium pouvant etre biologiquement erodes pour administration d'agents therapeutiques |
| EP2891716B1 (fr) * | 2012-08-28 | 2018-03-28 | Biocube System Inc. | Phase solide poreuse pour isoler rapidement des molécules biologiques pour une réaction d'amplification d'acides nucléiques à partir d'un échantillon biologique et son utilisation |
| RU2705986C2 (ru) | 2013-03-15 | 2019-11-13 | Айпоинт Фармасьютикалз Юэс, Инк. | Биоразлагаемые композиции на основе кремния для доставки терапевтических агентов |
| JP6443907B2 (ja) * | 2014-02-17 | 2018-12-26 | 浩文 山本 | 造影剤の腫瘍への集積を促進するための集積促進剤 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4243652A (en) * | 1978-07-14 | 1981-01-06 | The Procter & Gamble Company | Gastrointestinal scanning agent |
| DE68920778T2 (de) * | 1988-05-24 | 1995-05-18 | Anagen Uk Ltd | Magnetisch anziehbare Teilchen und Herstellungsverfahren. |
| US5928958A (en) * | 1994-07-27 | 1999-07-27 | Pilgrimm; Herbert | Superparamagnetic particles, process for their manufacture and usage |
| WO1997001304A1 (fr) * | 1995-06-29 | 1997-01-16 | Mallinckrodt Medical, Inc. | Particules d'apatite radiomarquees contenant un ion paramagnetique |
| JP3735990B2 (ja) * | 1997-01-28 | 2006-01-18 | 東ソー株式会社 | 磁性シリカゲルの製造方法 |
-
2000
- 2000-10-13 EP EP00972209A patent/EP1221974A2/fr not_active Withdrawn
- 2000-10-13 ES ES00972209T patent/ES2182731T1/es active Pending
- 2000-10-13 CA CA002387925A patent/CA2387925A1/fr not_active Abandoned
- 2000-10-13 BR BR0014877-6A patent/BR0014877A/pt not_active IP Right Cessation
- 2000-10-13 JP JP2001531415A patent/JP2003512336A/ja active Pending
- 2000-10-13 WO PCT/US2000/028615 patent/WO2001028587A2/fr not_active Ceased
- 2000-10-13 NZ NZ518311A patent/NZ518311A/en unknown
- 2000-10-13 DE DE1221974T patent/DE1221974T1/de active Pending
- 2000-10-13 CN CNB008173796A patent/CN1287859C/zh not_active Expired - Fee Related
- 2000-10-13 AU AU10905/01A patent/AU772755B2/en not_active Ceased
- 2000-10-13 KR KR1020027004933A patent/KR20020064299A/ko not_active Ceased
- 2000-10-13 HK HK02106551.6A patent/HK1045110A1/zh unknown
- 2000-10-13 IL IL14900400A patent/IL149004A0/xx unknown
- 2000-10-13 CZ CZ20021357A patent/CZ293919B6/cs not_active IP Right Cessation
- 2000-10-13 MX MXPA02003891A patent/MXPA02003891A/es not_active Application Discontinuation
-
2003
- 2003-03-10 JP JP2003063821A patent/JP2003321348A/ja not_active Withdrawn
-
2005
- 2005-03-28 JP JP2005093293A patent/JP2005200426A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CZ20021357A3 (cs) | 2002-11-13 |
| BR0014877A (pt) | 2002-06-11 |
| JP2003321348A (ja) | 2003-11-11 |
| AU1090501A (en) | 2001-04-30 |
| CN1420787A (zh) | 2003-05-28 |
| EP1221974A2 (fr) | 2002-07-17 |
| WO2001028587A2 (fr) | 2001-04-26 |
| CA2387925A1 (fr) | 2001-04-26 |
| JP2005200426A (ja) | 2005-07-28 |
| CN1287859C (zh) | 2006-12-06 |
| JP2003512336A (ja) | 2003-04-02 |
| ES2182731T1 (es) | 2003-03-16 |
| AU772755B2 (en) | 2004-05-06 |
| WO2001028587A3 (fr) | 2002-01-03 |
| DE1221974T1 (de) | 2003-02-06 |
| HK1045110A1 (zh) | 2002-11-15 |
| NZ518311A (en) | 2003-10-31 |
| IL149004A0 (en) | 2002-11-10 |
| KR20020064299A (ko) | 2002-08-07 |
| CZ293919B6 (cs) | 2004-08-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |