MXPA02002901A - Enzimas de ruta de enfocado lisosomal. - Google Patents
Enzimas de ruta de enfocado lisosomal.Info
- Publication number
- MXPA02002901A MXPA02002901A MXPA02002901A MXPA02002901A MXPA02002901A MX PA02002901 A MXPA02002901 A MX PA02002901A MX PA02002901 A MXPA02002901 A MX PA02002901A MX PA02002901 A MXPA02002901 A MX PA02002901A MX PA02002901 A MXPA02002901 A MX PA02002901A
- Authority
- MX
- Mexico
- Prior art keywords
- lysosomal targeting
- pathway enzymes
- targeting pathway
- methods
- enzyme
- Prior art date
Links
- 102000004190 Enzymes Human genes 0.000 title abstract 3
- 108090000790 Enzymes Proteins 0.000 title abstract 3
- 230000002132 lysosomal effect Effects 0.000 title abstract 2
- 230000037361 pathway Effects 0.000 title abstract 2
- 230000008685 targeting Effects 0.000 title abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1223—Phosphotransferases with a nitrogenous group as acceptor (2.7.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/04—Phosphoric diester hydrolases (3.1.4)
- C12Y301/04045—N-Acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (3.1.4.45)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Detergent Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15383199P | 1999-09-14 | 1999-09-14 | |
| PCT/US2000/021970 WO2001019955A2 (en) | 1999-09-14 | 2000-09-14 | Lysosomal targeting pathway enzymes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA02002901A true MXPA02002901A (es) | 2003-10-14 |
Family
ID=22548927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA02002901A MXPA02002901A (es) | 1999-09-14 | 2000-09-14 | Enzimas de ruta de enfocado lisosomal. |
Country Status (10)
| Country | Link |
|---|---|
| US (8) | US6534300B1 (es) |
| EP (1) | EP1224266B1 (es) |
| JP (1) | JP2003509043A (es) |
| AT (1) | ATE373086T1 (es) |
| AU (1) | AU783224B2 (es) |
| BR (1) | BR0014514A (es) |
| CA (1) | CA2383217C (es) |
| DE (1) | DE60036395T2 (es) |
| MX (1) | MXPA02002901A (es) |
| WO (1) | WO2001019955A2 (es) |
Families Citing this family (152)
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| US5858351A (en) | 1996-01-18 | 1999-01-12 | Avigen, Inc. | Methods for delivering DNA to muscle cells using recombinant adeno-associated virus vectors |
| US5830916A (en) | 1996-05-23 | 1998-11-03 | Duke University | Inhibitor of ceramidase |
| US5719031A (en) | 1996-08-14 | 1998-02-17 | Molecular Probes, Inc. | Dye labeled polymers as reagents for measuring polymer degradation |
| US5830850A (en) | 1996-08-28 | 1998-11-03 | Mount Sinai School Of Medicine Of The City Of New York | Methods for the treatment of bone resorption disorders, including osteoporosis |
| JPH1080280A (ja) | 1996-09-09 | 1998-03-31 | Shimadzu Corp | 核酸合成法 |
| US5773236A (en) | 1997-04-25 | 1998-06-30 | Molecule Probes, Inc. | Assay for glutathiane transferase using polyhaloaryl-substituted reporter molecules |
| US5939279A (en) | 1997-09-18 | 1999-08-17 | The Board Of Trustees Of The University Of Arkansas | Inhibition of bacterial binding by high-mannose oligosaccharides |
| EP1040117A4 (en) * | 1997-12-18 | 2005-03-09 | Human Genome Sciences Inc | 110 HUMAN SECRETATED PROTEINS |
| US6534300B1 (en) | 1999-09-14 | 2003-03-18 | Genzyme Glycobiology Research Institute, Inc. | Methods for producing highly phosphorylated lysosomal hydrolases |
| US6800472B2 (en) * | 2001-12-21 | 2004-10-05 | Genzyme Glycobiology Research Institute, Inc. | Expression of lysosomal hydrolase in cells expressing pro-N-acetylglucosamine-1-phosphodiester α-N-acetyl glucosimanidase |
-
2000
- 2000-08-10 US US09/635,872 patent/US6534300B1/en not_active Expired - Lifetime
- 2000-08-10 US US09/636,077 patent/US6537785B1/en not_active Expired - Lifetime
- 2000-08-10 US US09/636,060 patent/US6642038B1/en not_active Expired - Lifetime
- 2000-09-14 JP JP2001523727A patent/JP2003509043A/ja active Pending
- 2000-09-14 WO PCT/US2000/021970 patent/WO2001019955A2/en not_active Ceased
- 2000-09-14 MX MXPA02002901A patent/MXPA02002901A/es unknown
- 2000-09-14 BR BR0014514-9A patent/BR0014514A/pt not_active IP Right Cessation
- 2000-09-14 AT AT00961335T patent/ATE373086T1/de not_active IP Right Cessation
- 2000-09-14 AU AU73303/00A patent/AU783224B2/en not_active Expired
- 2000-09-14 DE DE60036395T patent/DE60036395T2/de not_active Expired - Lifetime
- 2000-09-14 EP EP00961335A patent/EP1224266B1/en not_active Expired - Lifetime
- 2000-09-14 CA CA2383217A patent/CA2383217C/en not_active Expired - Lifetime
-
2001
- 2001-07-02 US US09/895,072 patent/US6861242B2/en not_active Expired - Lifetime
- 2001-11-09 US US09/986,552 patent/US6670165B2/en not_active Expired - Lifetime
-
2003
- 2003-09-09 US US10/657,280 patent/US7067127B2/en not_active Expired - Lifetime
-
2005
- 2005-08-09 US US11/199,233 patent/US7371366B2/en not_active Expired - Lifetime
-
2008
- 2008-02-27 US US12/038,018 patent/US20080176285A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2383217A1 (en) | 2001-03-22 |
| DE60036395T2 (de) | 2008-06-12 |
| EP1224266B1 (en) | 2007-09-12 |
| US6861242B2 (en) | 2005-03-01 |
| BR0014514A (pt) | 2002-07-23 |
| US20020025550A1 (en) | 2002-02-28 |
| US6642038B1 (en) | 2003-11-04 |
| US20080176285A1 (en) | 2008-07-24 |
| JP2003509043A (ja) | 2003-03-11 |
| US6534300B1 (en) | 2003-03-18 |
| US6537785B1 (en) | 2003-03-25 |
| AU783224B2 (en) | 2005-10-06 |
| EP1224266A4 (en) | 2003-05-28 |
| AU7330300A (en) | 2001-04-17 |
| DE60036395D1 (de) | 2007-10-25 |
| US7067127B2 (en) | 2006-06-27 |
| WO2001019955A3 (en) | 2001-10-04 |
| US6670165B2 (en) | 2003-12-30 |
| US20060073498A1 (en) | 2006-04-06 |
| CA2383217C (en) | 2013-11-19 |
| US20020150981A1 (en) | 2002-10-17 |
| ATE373086T1 (de) | 2007-09-15 |
| US7371366B2 (en) | 2008-05-13 |
| EP1224266A2 (en) | 2002-07-24 |
| US20050089869A1 (en) | 2005-04-28 |
| WO2001019955A2 (en) | 2001-03-22 |
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