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MX9801963A - Derivados de benzotiazolona. - Google Patents

Derivados de benzotiazolona.

Info

Publication number
MX9801963A
MX9801963A MX9801963A MX9801963A MX9801963A MX 9801963 A MX9801963 A MX 9801963A MX 9801963 A MX9801963 A MX 9801963A MX 9801963 A MX9801963 A MX 9801963A MX 9801963 A MX9801963 A MX 9801963A
Authority
MX
Mexico
Prior art keywords
alkyl
halogen
optionally substituted
benzothiazolone derivatives
benzothiazolone
Prior art date
Application number
MX9801963A
Other languages
English (en)
Other versions
MXPA98001963A (es
Inventor
Roger Victor Bonnert
Roger Charles Brown
Peter Alan Cage
Francis Ince
Garry Pairaudeau
Original Assignee
Astra Pharma Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9518952.8A external-priority patent/GB9518952D0/en
Priority claimed from GBGB9614346.6A external-priority patent/GB9614346D0/en
Application filed by Astra Pharma Prod filed Critical Astra Pharma Prod
Publication of MX9801963A publication Critical patent/MX9801963A/es
Publication of MXPA98001963A publication Critical patent/MXPA98001963A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/03Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C311/04Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/23Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms
    • C07C311/24Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/11Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/12Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

SE describe un compuesto de la formula (I), incluyendo los isomeros opticos del mismo, en donde X representa -SO2NH- o -NHSO2-, p, q y r independientemente representan 2 o 3, Y representa tienilo opcionalmente sustituido con alquilo o halogeno, o feniltio o fenilo opcionalmente sustituido con alquilo o halogeno, y cada R representa independientemente hidrogeno o alquilo, y las sales, ésteres y amidas farmacéuticamente aceptables de los mismos.
MXPA/A/1998/001963A 1995-09-15 1998-03-12 Derivados de benzotiazolona MXPA98001963A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9518952.8A GB9518952D0 (en) 1995-09-15 1995-09-15 Compounds
GB9518952.8 1995-09-15
GBGB9614346.6A GB9614346D0 (en) 1996-07-10 1996-07-10 Benzothiazolone derivatives
GB9614346.6 1996-07-10

Publications (2)

Publication Number Publication Date
MX9801963A true MX9801963A (es) 1998-08-30
MXPA98001963A MXPA98001963A (es) 1998-11-12

Family

ID=

Also Published As

Publication number Publication date
AR004512A1 (es) 1998-12-16
US5977384A (en) 1999-11-02
NO981104D0 (no) 1998-03-12
CN1073098C (zh) 2001-10-17
GR3033681T3 (en) 2000-10-31
EP0850232B1 (en) 2000-03-15
BR9610316A (pt) 1999-07-06
HK1008781A1 (en) 1999-05-21
NZ318007A (en) 1999-07-29
NO310721B1 (no) 2001-08-20
TR199800457T2 (xx) 1998-07-21
IL123639A (en) 2002-04-21
JP3213327B2 (ja) 2001-10-02
EP0850232A1 (en) 1998-07-01
US5846989A (en) 1998-12-08
NZ332395A (en) 1999-02-25
SK282394B6 (sk) 2002-01-07
PL325517A1 (en) 1998-08-03
IS4679A (is) 1998-03-04
IL141955A0 (en) 2002-03-10
HUP9802393A3 (en) 2000-01-28
US5973167A (en) 1999-10-26
EE9800069A (et) 1998-10-15
HUP9802393A2 (hu) 1999-04-28
NZ332396A (en) 1999-02-25
WO1997010227A1 (en) 1997-03-20
JPH11512422A (ja) 1999-10-26
ATE190610T1 (de) 2000-04-15
US6008365A (en) 1999-12-28
IL123639A0 (en) 1998-10-30
DE69607183T2 (de) 2000-11-23
TW356468B (en) 1999-04-21
CY2227B1 (en) 2003-04-18
AU6937196A (en) 1997-04-01
AU706094B2 (en) 1999-06-10
PT850232E (pt) 2000-08-31
ES2146901T3 (es) 2000-08-16
CZ74098A3 (cs) 1998-08-12
EE03395B1 (et) 2001-04-16
NO981104L (no) 1998-05-14
DE69607183D1 (de) 2000-04-20
SK29598A3 (en) 1999-01-11
KR19990044674A (ko) 1999-06-25
IL141954A0 (en) 2002-03-10
CN1202163A (zh) 1998-12-16
NZ332397A (en) 1999-02-25
US6080869A (en) 2000-06-27
MY113518A (en) 2002-03-30
CA2231003A1 (en) 1997-03-20
IL141956A0 (en) 2002-03-10
CN1356323A (zh) 2002-07-03

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Legal Events

Date Code Title Description
FG Grant or registration
PD Change of proprietorship

Owner name: ASTRAZENECA AB

MM Annulment or lapse due to non-payment of fees