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MX9707974A - Derivados de 10, 13, 15-trioxatriciclo [9.2.1.1 9.6]-pentadecanona, procedimientos para su preparacion y medicamentos que contienen estos compuestos. - Google Patents

Derivados de 10, 13, 15-trioxatriciclo [9.2.1.1 9.6]-pentadecanona, procedimientos para su preparacion y medicamentos que contienen estos compuestos.

Info

Publication number
MX9707974A
MX9707974A MX9707974A MX9707974A MX9707974A MX 9707974 A MX9707974 A MX 9707974A MX 9707974 A MX9707974 A MX 9707974A MX 9707974 A MX9707974 A MX 9707974A MX 9707974 A MX9707974 A MX 9707974A
Authority
MX
Mexico
Prior art keywords
derivatives
preparation
trioxatricycle
pentadecanone
procedures
Prior art date
Application number
MX9707974A
Other languages
English (en)
Other versions
MXPA97007974A (es
Inventor
Dagmar Hoeltje
Christian Eeckhout
Emil Finner
Ulf Preuschoff
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of MXPA97007974A publication Critical patent/MXPA97007974A/es
Publication of MX9707974A publication Critical patent/MX9707974A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se describen derivados de N-desmetil-N-isopropil-eritro-micina-A- espiroacetal estrechados en el anillo con propiedades agonistas de motilina gastrointestinalmente eficaces y su preparacion.
MX9707974A 1996-10-24 1997-10-16 Derivados de 10, 13, 15-trioxatriciclo [9.2.1.1 9.6]-pentadecanona, procedimientos para su preparacion y medicamentos que contienen estos compuestos. MX9707974A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19644195.1 1996-10-24
DE19644195A DE19644195A1 (de) 1996-10-24 1996-10-24 10,13,15-Trioxatricyclo[9.2.1.1.·9·.·6·]-pentadecanon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19644195,1 1996-10-24

Publications (2)

Publication Number Publication Date
MXPA97007974A MXPA97007974A (es) 1998-04-01
MX9707974A true MX9707974A (es) 1998-04-30

Family

ID=7809858

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9707974A MX9707974A (es) 1996-10-24 1997-10-16 Derivados de 10, 13, 15-trioxatriciclo [9.2.1.1 9.6]-pentadecanona, procedimientos para su preparacion y medicamentos que contienen estos compuestos.

Country Status (26)

Country Link
US (1) US5912235A (es)
EP (1) EP0838469B1 (es)
JP (1) JP4175682B2 (es)
KR (1) KR100466495B1 (es)
CN (1) CN1093133C (es)
AR (1) AR009809A1 (es)
AT (1) ATE211745T1 (es)
AU (1) AU726092B2 (es)
BR (2) BR9705157A (es)
CA (1) CA2219311C (es)
CZ (1) CZ291768B6 (es)
DE (2) DE19644195A1 (es)
DK (1) DK0838469T3 (es)
DZ (1) DZ2322A1 (es)
ES (1) ES2170318T3 (es)
HU (1) HU222540B1 (es)
IL (1) IL121969A (es)
MX (1) MX9707974A (es)
NO (1) NO308362B1 (es)
NZ (1) NZ328979A (es)
PL (1) PL184693B1 (es)
PT (1) PT838469E (es)
RU (1) RU2181727C2 (es)
SK (1) SK283114B6 (es)
UA (1) UA44310C2 (es)
ZA (1) ZA979059B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998023629A1 (fr) * 1996-11-26 1998-06-04 Chugai Seiyaku Kabushiki Kaisha Composes de macrolides comportant une chaine a 13 elements, medicament les contenant et leur procede de preparation
KR20040066186A (ko) * 2000-08-17 2004-07-23 샤단호칭키타사토겐큐쇼 신규 슈도에리쓰로마이신 유도체
JP2003007917A (ja) * 2001-06-19 2003-01-10 Sanyo Electric Co Ltd 回路装置の製造方法
US6986882B2 (en) * 2002-01-17 2006-01-17 Astrazeneca Ab Therapy for functional dyspepsia
ES2338789T3 (es) 2003-06-18 2010-05-12 Tranzyme Pharma Inc. Antagonistas macrociclicos del receptor de motilina.
GB0611907D0 (en) 2006-06-15 2006-07-26 Glaxo Group Ltd Compounds
US20080312209A1 (en) 2005-07-12 2008-12-18 Glaxo Group Limited Piperazine Heteroaryl Derivatives as Gpr38 Agonists
MY150098A (en) 2005-07-26 2013-11-29 Glaxo Group Ltd Benzylpiperazine derivates and their medical use
NZ568763A (en) * 2005-12-08 2010-04-30 Pfizer Method for demethylating the 3'-dimethylamino group of erythromycin compounds
DK2041093T3 (da) 2006-06-28 2010-08-02 Glaxo Group Ltd Til behandling af GPR38-receptor medierede sygdomme anvendelige piperazinylderivativer
CA2662897C (en) 2006-09-11 2017-11-07 Tranzyme Pharma, Inc. Macrocyclic antagonists of the motilin receptor for treatment of gastrointestinal dysmotility disorders
KR101120483B1 (ko) * 2006-12-05 2012-02-29 브리스톨-마이어즈 스퀴브 컴페니 모틸라이드 다형체
WO2010098145A1 (en) 2009-02-27 2010-09-02 Raqualia Pharma Inc. Oxyindole derivatives with motilin receptor agonistic activity
EP2979702A4 (en) * 2013-03-25 2016-11-16 Zeria Pharm Co Ltd GASTROKINETIC POSTPRANDIAL MEDIUM

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725385A (en) * 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders
DE4200145A1 (de) * 1992-01-07 1993-07-08 Kali Chemie Pharma Gmbh 7,10-epoxy-oxacyclododecan-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
NO974934D0 (no) 1997-10-24
AU726092B2 (en) 2000-11-02
DZ2322A1 (fr) 2002-12-28
CN1186808A (zh) 1998-07-08
NO308362B1 (no) 2000-09-04
NZ328979A (en) 1998-10-28
CZ291768B6 (cs) 2003-05-14
CZ310697A3 (cs) 1998-06-17
SK283114B6 (sk) 2003-02-04
IL121969A (en) 2000-06-29
EP0838469A1 (de) 1998-04-29
JP4175682B2 (ja) 2008-11-05
PT838469E (pt) 2002-05-31
NO974934L (no) 1998-04-27
EP0838469B1 (de) 2002-01-09
BR9705143A (pt) 2000-12-12
CA2219311A1 (en) 1998-04-24
PL322802A1 (en) 1998-04-27
DK0838469T3 (da) 2002-03-18
HK1010885A1 (en) 1999-07-02
KR100466495B1 (ko) 2005-05-27
ZA979059B (en) 1998-05-07
ES2170318T3 (es) 2002-08-01
IL121969A0 (en) 1998-03-10
PL184693B1 (pl) 2002-12-31
RU2181727C2 (ru) 2002-04-27
DE19644195A1 (de) 1998-04-30
BR9705157A (pt) 1999-09-28
AU4278897A (en) 1998-04-30
HUP9701660A3 (en) 1998-08-28
AR009809A1 (es) 2000-05-03
HUP9701660A2 (hu) 1998-05-28
HU222540B1 (hu) 2003-08-28
KR19980032626A (ko) 1998-07-25
US5912235A (en) 1999-06-15
UA44310C2 (uk) 2002-02-15
CN1093133C (zh) 2002-10-23
HU9701660D0 (en) 1997-12-29
SK141997A3 (en) 1998-05-06
JPH10130297A (ja) 1998-05-19
DE59705964D1 (de) 2002-02-14
ATE211745T1 (de) 2002-01-15
CA2219311C (en) 2007-09-04

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees