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MX9706461A - Sales de acido clavulanico. - Google Patents

Sales de acido clavulanico.

Info

Publication number
MX9706461A
MX9706461A MX9706461A MX9706461A MX9706461A MX 9706461 A MX9706461 A MX 9706461A MX 9706461 A MX9706461 A MX 9706461A MX 9706461 A MX9706461 A MX 9706461A MX 9706461 A MX9706461 A MX 9706461A
Authority
MX
Mexico
Prior art keywords
clavulanic acid
acid salts
salt
formula
salts
Prior art date
Application number
MX9706461A
Other languages
English (en)
Other versions
MXPA97006461A (es
Inventor
George Leo Callewaert
Original Assignee
Spurcourt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26306586&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX9706461(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9503839.4A external-priority patent/GB9503839D0/en
Application filed by Spurcourt Ltd filed Critical Spurcourt Ltd
Publication of MX9706461A publication Critical patent/MX9706461A/es
Publication of MXPA97006461A publication Critical patent/MXPA97006461A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/27Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D503/00Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D503/00Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D503/10Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Las sales son preparadas haciendo reaccionar una benzidrilamina de formula I (o una sal de la misma) con ácido clavulánico (o una sal de mismo) en un solvente orgánico, y asilar la sal resultante. En la formula I, cada R1 y R2 son preferentemente hidrogeno o un substituyente aceptable (Ver Formula) Las sales del ácido clavulánico pueden ser usadas en formulaciones farmacéuticas junto con un agente farmacéuticamente aceptable, y, opcionalmente, un antibiotico beta-lactama.
MXPA/A/1997/006461A 1995-02-25 1997-08-25 Sales de acido clavulanico MXPA97006461A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9503839.4A GB9503839D0 (en) 1995-02-25 1995-02-25 Claulanic acid salt
GB9503839.4 1995-02-25
GBGB9520915.1A GB9520915D0 (en) 1995-02-25 1995-10-12 Clavulanic acid salt
GB9520915.1 1995-10-12

Publications (2)

Publication Number Publication Date
MX9706461A true MX9706461A (es) 1998-06-28
MXPA97006461A MXPA97006461A (es) 1998-10-30

Family

ID=

Also Published As

Publication number Publication date
MD1744F2 (ro) 2001-09-30
BR9607258A (pt) 1997-12-30
AP9701067A0 (en) 1997-10-31
FI973287A7 (fi) 1997-08-22
SK111197A3 (en) 1998-01-14
EP0729961A1 (en) 1996-09-04
SE9703056L (sv) 1997-08-25
AU4726196A (en) 1996-09-18
MD970269A (en) 1999-05-31
CZ266697A3 (en) 1997-11-12
IS4541A (is) 1997-08-08
FI973287L (fi) 1997-08-22
BG62490B1 (bg) 1999-12-30
OA10444A (en) 2002-03-26
SE9703056D0 (sv) 1997-08-25
PL321871A1 (en) 1997-12-22
CA2213563A1 (en) 1996-09-06
NZ301765A (en) 1999-10-28
AP9701116A0 (en) 1997-10-31
EE9700186A (et) 1998-02-16
ZA961457B (en) 1996-09-26
ATE211143T1 (de) 2002-01-15
US5726170A (en) 1998-03-10
JPH11501023A (ja) 1999-01-26
HK1006571A1 (en) 1999-03-05
TR199700828T1 (xx) 1998-04-21
FI973287A0 (fi) 1997-08-08
BG101884A (en) 1998-10-30
AU691727B2 (en) 1998-05-21
DE69618045D1 (de) 2002-01-31
CN1175952A (zh) 1998-03-11
NO973744L (no) 1997-08-14
AP749A (en) 1999-07-05
EP0729961B1 (en) 2001-12-19
NO973744D0 (no) 1997-08-14
WO1996026944A1 (en) 1996-09-06
IL117217A0 (en) 1996-06-18

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