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MX9704049A - Dispositivo de suministro por electrotransporte. - Google Patents

Dispositivo de suministro por electrotransporte.

Info

Publication number
MX9704049A
MX9704049A MX9704049A MX9704049A MX9704049A MX 9704049 A MX9704049 A MX 9704049A MX 9704049 A MX9704049 A MX 9704049A MX 9704049 A MX9704049 A MX 9704049A MX 9704049 A MX9704049 A MX 9704049A
Authority
MX
Mexico
Prior art keywords
resistant
heat
perfluoroelastomer composition
perfluoroelastomer
composition
Prior art date
Application number
MX9704049A
Other languages
English (en)
Inventor
Larry A Mcnichols
John D Badzinski
Ronald P Haak
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of MX9704049A publication Critical patent/MX9704049A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0412Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303Constructional details

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Electrotherapy Devices (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Reciprocating Pumps (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preliminary Treatment Of Fibers (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Water Treatment By Electricity Or Magnetism (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Pigments, Carbon Blacks, Or Wood Stains (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • External Artificial Organs (AREA)

Abstract

Un dispositivo de suministro por electrotransporte (410) incluye los circuitos de control para suministrar de una manera discontinua una substancia benéfica (v.gr. un fármaco) a través de una superficie del cuerpo (v. gr. la piel (400)). Por ejemplo, el dispositivo puede ser del tipo que se activa manualmente por el paciente u otro personal médico para activar el suministro del fármaco por electrotransporte. Una vez que se ha activado el suministro por electrotransporte, un cronometro (221) cuenta un intervalo de transicion, típicamente durante cerca de 1 minuto, durante el cual se permite que opere el dispositivo, y se permite que se estabilice la impedancia de la superficie del cuerpo (400). Posteriormente, se monitorean la corriente y el voltaje de electrotransporte, y se comparan con límites predeterminados. Si se deja el intervalo de transicion, se permite tener tolerancias más estrechas en el monitores de la corriente suministrada. La figura más representativa de la invencion es la numero 1A.
MX9704049A 1994-12-08 1995-11-27 Dispositivo de suministro por electrotransporte. MX9704049A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/353,036 US5697896A (en) 1994-12-08 1994-12-08 Electrotransport delivery device
PCT/US1995/015015 WO1996017651A1 (en) 1994-12-08 1995-11-27 Electrotransport delivery device

Publications (1)

Publication Number Publication Date
MX9704049A true MX9704049A (es) 1997-10-31

Family

ID=23387488

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9704049A MX9704049A (es) 1994-12-08 1995-11-27 Dispositivo de suministro por electrotransporte.

Country Status (15)

Country Link
US (2) US5697896A (es)
EP (1) EP0796127B1 (es)
JP (1) JP3848365B2 (es)
KR (1) KR100376723B1 (es)
AT (1) ATE170769T1 (es)
AU (1) AU688644B2 (es)
CA (1) CA2200602C (es)
DE (1) DE69504705T2 (es)
DK (1) DK0796127T3 (es)
ES (1) ES2122700T3 (es)
FI (1) FI116272B (es)
MX (1) MX9704049A (es)
NO (1) NO324646B1 (es)
NZ (1) NZ296913A (es)
WO (1) WO1996017651A1 (es)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6956032B1 (en) 1986-04-18 2005-10-18 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
JP3523334B2 (ja) * 1994-07-02 2004-04-26 久光製薬株式会社 イオントフォレ−シス用プラスター構造体
US5876368A (en) * 1994-09-30 1999-03-02 Becton Dickinson And Company Iontophoretic drug delivery device having improved controller
IE960312A1 (en) 1995-06-02 1996-12-11 Alza Corp An electrotransport delivery device with voltage boosting¹circuit
US6425892B2 (en) * 1995-06-05 2002-07-30 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
AU696832B2 (en) * 1995-08-31 1998-09-17 Hisamitsu Pharmaceutical Co., Inc. Iontophoresis system and its control process of current
US5676648A (en) * 1996-05-08 1997-10-14 The Aps Organization, Llp Iontophoretic drug delivery apparatus and method for use
US6385487B1 (en) 1996-05-08 2002-05-07 Biophoretic Therapeutic Systems, Llc Methods for electrokinetic delivery of medicaments
US5908401A (en) * 1996-05-08 1999-06-01 The Aps Organization, Llp Method for iontophoretic delivery of antiviral agents
US6650934B2 (en) * 1996-12-17 2003-11-18 Alza Corp Polymeric foam reservoirs for an electrotransport delivery device
US6246904B1 (en) * 1996-12-17 2001-06-12 Alza Corporation Electrotransport drug delivery reservoirs containing inert fillers
US6119036A (en) * 1997-03-26 2000-09-12 The Board Of Regents Of The University Of Oklahoma Iontophoretic transdermal delivery device
US6208891B1 (en) * 1997-04-04 2001-03-27 Drug Delivery Technologies, Inc. Disabling circuit for an iontophoretic system
US6029083A (en) * 1997-04-04 2000-02-22 Becton, Dickinson And Company Circuit and method for automatically turning off an iontophoresis system
FR2766093B1 (fr) 1997-07-15 1999-09-03 Lhd Lab Hygiene Dietetique Procede de commande d'un dispositif d'administration transdermique de medicament sous champ electrique
WO1999018797A1 (en) 1997-10-09 1999-04-22 Emory University Method and devices for transdermal delivery of lithium
US6775569B2 (en) * 1997-11-05 2004-08-10 Hisamitsu Pharmaceutical Co., Inc. Electroporation device for in vivo delivery of therapeutic agents
USRE37796E1 (en) 1997-12-16 2002-07-23 Biophoretic Therapeutic Systems, Llc Methods for iontophoretic delivery of antiviral agents
FR2778108B1 (fr) * 1998-04-30 2000-07-21 Lhd Lab Hygiene Dietetique Dispositif d'administration transdermique de medicament par ionophorese
US6949081B1 (en) * 1998-08-26 2005-09-27 Non-Invasive Technology, Inc. Sensing and interactive drug delivery
US6148231A (en) * 1998-09-15 2000-11-14 Biophoretic Therapeutic Systems, Llc Iontophoretic drug delivery electrodes and method
US6597946B2 (en) * 1998-11-09 2003-07-22 Transpharma Ltd. Electronic card for transdermal drug delivery and analyte extraction
US6148232A (en) 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6708060B1 (en) 1998-11-09 2004-03-16 Transpharma Ltd. Handheld apparatus and method for transdermal drug delivery and analyte extraction
US6611706B2 (en) 1998-11-09 2003-08-26 Transpharma Ltd. Monopolar and bipolar current application for transdermal drug delivery and analyte extraction
JP2000237330A (ja) * 1999-02-24 2000-09-05 Hisamitsu Pharmaceut Co Inc イオントフォレーシス用デバイス
US6477410B1 (en) 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US6553253B1 (en) 1999-03-12 2003-04-22 Biophoretic Therapeutic Systems, Llc Method and system for electrokinetic delivery of a substance
US6792306B2 (en) * 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
US7127285B2 (en) 1999-03-12 2006-10-24 Transport Pharmaceuticals Inc. Systems and methods for electrokinetic delivery of a substance
US6283938B1 (en) * 1999-05-04 2001-09-04 Mcconnell Daniel E. Medicating bandage and controllable permeable membrane
US6385488B1 (en) 1999-05-20 2002-05-07 Vyteris, Inc. Circuits for increasing the reliability of an iontophoretic system
JP4162813B2 (ja) * 1999-10-28 2008-10-08 久光製薬株式会社 イオントフォレーシス装置
US20010041869A1 (en) * 2000-03-23 2001-11-15 Causey James D. Control tabs for infusion devices and methods of using the same
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
AU2002353444A1 (en) * 2001-11-07 2003-05-19 Transpharma Medical Ltd. Integrated transdermal drug delivery system
WO2003089043A2 (en) * 2002-04-19 2003-10-30 Transpharma Medical Ltd. Handheld transdermal drug delivery and analyte extraction
AU2003285889A1 (en) * 2002-10-15 2004-05-04 Medtronic Inc. Control of treatment therapy during start-up and during operation of a medical device system
US8738136B2 (en) 2002-10-15 2014-05-27 Medtronic, Inc. Clustering of recorded patient neurological activity to determine length of a neurological event
US20040267240A1 (en) * 2003-01-29 2004-12-30 Yossi Gross Active drug delivery in the gastrointestinal tract
US20050058701A1 (en) * 2003-01-29 2005-03-17 Yossi Gross Active drug delivery in the gastrointestinal tract
CA2514392A1 (en) * 2003-01-29 2004-08-12 E-Pill Pharma Ltd. Active drug delivery in the gastrointestinal tract
WO2004104493A2 (en) 2003-05-21 2004-12-02 Alexza Pharmaceuticals, Inc. Methods of controlling uniformity of substrate temperature and self-contained heating unit and drug-supply unit employing same
US7706873B2 (en) * 2004-05-05 2010-04-27 Mario Ammirati System and method for controlled delivery of a therapeutic agent to a target location within an internal body tissue
US7402777B2 (en) * 2004-05-20 2008-07-22 Alexza Pharmaceuticals, Inc. Stable initiator compositions and igniters
CA2576961A1 (en) 2004-08-12 2006-03-02 Alexza Pharmaceuticals, Inc. Aerosol drug delivery device incorporating percussively activated heat packages
EP1802258A4 (en) 2004-09-13 2015-09-23 Chrono Therapeutics Inc BIOSYNCHRONE TRANSDERMAL MEDICINES
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
US10130801B1 (en) * 2005-02-07 2018-11-20 Ipventure, Inc. Electronic transdermal chemical delivery
US7856263B2 (en) * 2005-04-22 2010-12-21 Travanti Pharma Inc. Transdermal systems for the delivery of therapeutic agents including granisetron using iontophoresis
CN101175529A (zh) * 2005-05-19 2008-05-07 埃-皮尔制药公司 用于在组织中产生一氧化氮的可摄入装置
US20070203534A1 (en) * 2006-02-13 2007-08-30 Robert Tapper Stimulating galvanic or slow AC current for therapeutic physiological effects
WO2007120747A2 (en) * 2006-04-13 2007-10-25 Nupathe Inc. Transdermal methods and systems for the delivery of anti-migraine compounds
US20110054391A1 (en) * 2006-07-28 2011-03-03 Ward W Kenneth Analyte sensing and response system
US7853320B1 (en) 2007-05-31 2010-12-14 Purdue Pharma L.P. Transdermal device having mechanical assist for porator-to-skin contact
US8095213B1 (en) * 2007-05-31 2012-01-10 Purdue Pharma L.P. Transdermal patch
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
US8047399B1 (en) 2007-07-05 2011-11-01 Purdue Pharma L.P. Dispenser for transdermal devices
CA2704740C (en) 2007-10-09 2016-05-17 Transpharma Ltd. Magnetic patch coupling
CA2696227A1 (en) 2007-10-17 2009-04-23 Transpharma Medical Ltd. Dissolution rate verification
EP2394594A1 (en) 2007-12-05 2011-12-14 Syneron Medical Ltd. A disposable electromagnetic energy applicator and method of using it
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US8155737B2 (en) * 2008-06-19 2012-04-10 Nupathe, Inc. Pharmacokinetics of iontophoretic sumatriptan administration
US8366600B2 (en) * 2008-06-19 2013-02-05 Nupathe Inc. Polyamine enhanced formulations for triptan compound iontophoresis
NZ622157A (en) 2008-12-30 2015-10-30 Teva Pharmaceuticals Int Gmbh Electronic control of drug delivery system
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
US20110066175A1 (en) * 2009-05-07 2011-03-17 Rainbow Medical Ltd. Gastric anchor
US20100286587A1 (en) * 2009-05-07 2010-11-11 Yossi Gross Sublingual electrical drug delivery
US8414559B2 (en) 2009-05-07 2013-04-09 Rainbow Medical Ltd. Gastroretentive duodenal pill
CA2770211A1 (en) 2009-08-10 2011-02-17 Nupathe Inc. Methods for iontophoretically treating nausea and migraine
US20110087153A1 (en) * 2009-10-13 2011-04-14 Angelov Angel S Transdermal Methods And Systems For The Delivery Of Rizatriptan
US9327105B2 (en) 2010-03-26 2016-05-03 Itrace Biomedical Inc. Active transdermal drug delivery system and the method thereof
DK2557924T3 (da) 2010-04-13 2019-09-23 Relmada Therapeutics Inc Dermale farmaceutiske sammensætninger af 1-methyl-2',6'-pipecoloxylidid og fremgangsmåde til deres anvendelse
BR112013012117A8 (pt) 2010-11-23 2017-10-10 Nupathe Inc Sistema de distribuição de fármaco iontoforético coempacotado de utilização única coempacotado autocontido, usos de fármaco e de composto de triptano
US8428709B1 (en) 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
US8781571B2 (en) * 2011-03-31 2014-07-15 Incline Therapeutics, Inc. Switch validation circuit and method
US9731121B2 (en) 2011-03-31 2017-08-15 Incline Therapeutics, Inc. Switch validation circuit and method
US8428708B1 (en) 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
WO2013006643A1 (en) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions and methods for treatment of symptoms in parkinson's disease patients
US9700245B2 (en) 2011-09-23 2017-07-11 Itrace Biomedical Inc. Transdermal analyte extraction and detection system and the method thereof
US9710607B2 (en) 2013-01-15 2017-07-18 Itrace Biomedical Inc. Portable electronic therapy device and the method thereof
US10179239B2 (en) 2013-01-15 2019-01-15 Itrace Biomedical Inc. Personalized pain management treatments
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
JP2018511355A (ja) 2015-01-28 2018-04-26 クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. 薬剤送達方法及びシステム
JP2018511127A (ja) 2015-03-12 2018-04-19 クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. 渇望入力及び支援システム
JP2020503950A (ja) 2017-01-06 2020-02-06 クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. 経皮薬剤送達の装置及び方法
US11251635B2 (en) 2017-12-19 2022-02-15 Welch Allyn, Inc. Vital signs monitor with a removable and dischargable battery
US11596779B2 (en) 2018-05-29 2023-03-07 Morningside Venture Investments Limited Drug delivery methods and systems
CA3119992A1 (en) 2018-11-16 2020-05-22 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991755A (en) * 1973-07-27 1976-11-16 Medicon, Inc. Iontophoresis apparatus for applying local anesthetics
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4340047A (en) * 1978-10-18 1982-07-20 Robert Tapper Iontophoretic treatment apparatus
US4250878A (en) * 1978-11-22 1981-02-17 Motion Control, Inc. Non-invasive chemical species delivery apparatus and method
JPS56501274A (es) * 1979-10-10 1981-09-10
US4383529A (en) * 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4406658A (en) * 1981-03-06 1983-09-27 Medtronic, Inc. Iontophoretic device with reversible polarity
JPS5810066A (ja) * 1981-07-10 1983-01-20 株式会社アドバンス イオントフオレ−ゼ用プラスタ−構造体
US4456012A (en) * 1982-02-22 1984-06-26 Medtronic, Inc. Iontophoretic and electrical tissue stimulation device
EP0092015A1 (fr) * 1982-04-16 1983-10-26 Roland Brodard Dispositif d'ionisation
US4931046A (en) * 1987-05-15 1990-06-05 Newman Martin H Iontophoresis drug delivery system
US5013293A (en) * 1987-05-28 1991-05-07 Drug Delivery Systems Inc. Pulsating transdermal drug delivery system
US4942883A (en) * 1987-09-29 1990-07-24 Newman Martin H Drug delivery device
US5006108A (en) * 1988-11-16 1991-04-09 Noven Pharmaceuticals, Inc. Apparatus for iontophoretic drug delivery
DE4028125A1 (de) * 1990-01-17 1991-07-18 Klimke Markus Applikationsvorrichtung fuer die geregelte dosierung verschiedener pharmakons mittels elektrischem strom zum perkutanen transport zur lokalen und systemischen therapie
US5207752A (en) * 1990-03-30 1993-05-04 Alza Corporation Iontophoretic drug delivery system with two-stage delivery profile
CA2084734C (en) * 1991-12-17 1998-12-01 John L. Haynes Iontophoresis system having features for reducing skin irritation

Also Published As

Publication number Publication date
KR100376723B1 (ko) 2003-06-09
ES2122700T3 (es) 1998-12-16
FI116272B (fi) 2005-10-31
NZ296913A (en) 1999-07-29
ATE170769T1 (de) 1998-09-15
NO324646B1 (no) 2007-11-26
EP0796127B1 (en) 1998-09-09
US6090095A (en) 2000-07-18
US5697896A (en) 1997-12-16
AU688644B2 (en) 1998-03-12
CA2200602A1 (en) 1996-06-13
DE69504705T2 (de) 1999-02-25
NO972498D0 (no) 1997-06-02
CA2200602C (en) 2010-03-23
JPH10510179A (ja) 1998-10-06
FI972414A0 (fi) 1997-06-06
JP3848365B2 (ja) 2006-11-22
WO1996017651A1 (en) 1996-06-13
DE69504705D1 (de) 1998-10-15
EP0796127A1 (en) 1997-09-24
FI972414L (fi) 1997-06-06
DK0796127T3 (da) 1999-06-07
NO972498L (no) 1997-08-06
AU4165196A (en) 1996-06-26

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