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MX9701512A - Uso del factor de celulas madre y receptor de interleucina-6 soluble para la expansion ex vivo de celulas multipotenciales hematopoyeticas. - Google Patents

Uso del factor de celulas madre y receptor de interleucina-6 soluble para la expansion ex vivo de celulas multipotenciales hematopoyeticas.

Info

Publication number
MX9701512A
MX9701512A MX9701512A MX9701512A MX9701512A MX 9701512 A MX9701512 A MX 9701512A MX 9701512 A MX9701512 A MX 9701512A MX 9701512 A MX9701512 A MX 9701512A MX 9701512 A MX9701512 A MX 9701512A
Authority
MX
Mexico
Prior art keywords
receptor
stem cell
cell factor
hematopoietic
soluble interleukin
Prior art date
Application number
MX9701512A
Other languages
English (en)
Inventor
Tatsutoshi Nakahata
Original Assignee
Amgen Inc
Tosoh Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/340,559 external-priority patent/US5610056A/en
Application filed by Amgen Inc, Tosoh Corp filed Critical Amgen Inc
Publication of MX9701512A publication Critical patent/MX9701512A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0641—Erythrocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/36—Lipids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

El factor de células madre en combinacion con el receptor de interleucina-6 soluble, interleucina-6, para el señalizador gp130, soporta la prolifracion, diferenciacion y maduracion terminal de células de sangre a partir de células multipotenciales hamatopoyéticas de humano, normales.
MX9701512A 1994-11-16 1995-11-16 Uso del factor de celulas madre y receptor de interleucina-6 soluble para la expansion ex vivo de celulas multipotenciales hematopoyeticas. MX9701512A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/340,559 US5610056A (en) 1994-11-16 1994-11-16 Use of stem cell factor interleukin-6 and soluble interleukin-6 receptor to induce the development of hematopoietic stem cells
US39314695A 1995-02-21 1995-02-21
PCT/US1995/014999 WO1996015230A2 (en) 1994-11-16 1995-11-16 Use of stem cell factor and soluble interleukin-6 receptor for the ex vivo expansion of hematopoietic multipotential cells

Publications (1)

Publication Number Publication Date
MX9701512A true MX9701512A (es) 1997-05-31

Family

ID=26992162

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9701512A MX9701512A (es) 1994-11-16 1995-11-16 Uso del factor de celulas madre y receptor de interleucina-6 soluble para la expansion ex vivo de celulas multipotenciales hematopoyeticas.

Country Status (13)

Country Link
US (1) US5861315A (es)
EP (1) EP0793714B1 (es)
JP (1) JP3600244B2 (es)
CN (1) CN1170926C (es)
AT (1) ATE221118T1 (es)
AU (1) AU699479B2 (es)
CA (1) CA2198603C (es)
DE (1) DE69527540T2 (es)
DK (1) DK0793714T3 (es)
ES (1) ES2180665T3 (es)
MX (1) MX9701512A (es)
PT (1) PT793714E (es)
WO (1) WO1996015230A2 (es)

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CN1564864A (zh) * 2001-08-07 2005-01-12 麒麟麦酒株式会社 造血干细胞的制备方法
WO2003042405A2 (en) * 2001-11-15 2003-05-22 Children's Medical Center Corporation Methods of isolation, expansion and differentiation of fetal stem cells from chorionic villus, amniotic fluid, and placenta and therapeutic uses thereof
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WO2003080806A2 (en) * 2002-03-18 2003-10-02 National Jewish Medical And Research Center Method for production of neutrophils and uses therefor
US20040161419A1 (en) * 2002-04-19 2004-08-19 Strom Stephen C. Placental stem cells and uses thereof
EP1497435A4 (en) * 2002-04-19 2005-07-27 Univ Pittsburgh STEM CELLS DERIVED FROM PLAZENTA AND THEIR USES
US20040044300A1 (en) * 2002-09-03 2004-03-04 Donnie Rudd Method of replenishing cells damaged by treatment for cancer
US20040076620A1 (en) * 2002-09-03 2004-04-22 Donnie Rudd Method of repairing primate mammalian tissue
US20040076605A1 (en) * 2002-09-03 2004-04-22 Donnie Rudd Method of regenerating human tissue
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US20040042997A1 (en) * 2002-09-03 2004-03-04 Donnie Rudd Method of regenerating human tissue
US20040077985A1 (en) * 2002-09-03 2004-04-22 Donnie Rudd Method of replenishing cells damaged by treatment for cancer
EP1400587A1 (en) * 2002-09-19 2004-03-24 MainGen Biotechnologie GmbH Use of a fusion polypeptide for obtaining pluripotent non-embryonic stem cells
AU2003295444A1 (en) * 2002-11-15 2004-06-15 The Board Of Trustees Of The University Of Illinois Methods for in vitro expansion of hematopoietic stem cells
CA2505534A1 (en) * 2002-11-26 2004-06-10 Anthrogenesis Corporation Cytotherapeutics, cytotherapeutic units and methods for treatments using them
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US20100172830A1 (en) * 2007-03-29 2010-07-08 Cellx Inc. Extraembryonic Tissue cells and method of use thereof
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Also Published As

Publication number Publication date
DK0793714T3 (da) 2002-09-02
EP0793714A2 (en) 1997-09-10
DE69527540D1 (de) 2002-08-29
CA2198603C (en) 2000-06-27
CN1224461A (zh) 1999-07-28
JP3600244B2 (ja) 2004-12-15
AU699479B2 (en) 1998-12-03
AU4407396A (en) 1996-06-06
JPH10509040A (ja) 1998-09-08
PT793714E (pt) 2002-12-31
CN1170926C (zh) 2004-10-13
EP0793714B1 (en) 2002-07-24
US5861315A (en) 1999-01-19
ES2180665T3 (es) 2003-02-16
WO1996015230A2 (en) 1996-05-23
CA2198603A1 (en) 1996-05-23
ATE221118T1 (de) 2002-08-15
WO1996015230A3 (en) 1996-07-11
DE69527540T2 (de) 2003-01-30

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