MX9700712A - Derivados de estreptogramina, su preparacion y las composiciones farmaceuticas que los contienen. - Google Patents
Derivados de estreptogramina, su preparacion y las composiciones farmaceuticas que los contienen.Info
- Publication number
- MX9700712A MX9700712A MX9700712A MX9700712A MX9700712A MX 9700712 A MX9700712 A MX 9700712A MX 9700712 A MX9700712 A MX 9700712A MX 9700712 A MX9700712 A MX 9700712A MX 9700712 A MX9700712 A MX 9700712A
- Authority
- MX
- Mexico
- Prior art keywords
- same
- radical
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical group [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 150000003254 radicals Chemical class 0.000 abstract 2
- YVMBAUWDIGJRNY-BESUKNQGSA-N 4o8o7q7iu4 Chemical compound C1C(=O)C[C@H](O)\C=C(/C)\C=C\CNC(=O)\C=C\[C@@H](C)[C@@H](C(C)C)OC(=O)C2=CCCN2C(=O)C2=COC1=N2.N([C@@H]1C(=O)N[C@@H](C(N2CCC[C@H]2C(=O)N(C)[C@@H](CC=2C=CC(=CC=2)N(C)C)C(=O)N2CCC(=O)C[C@H]2C(=O)N[C@H](C(=O)O[C@@H]1C)C=1C=CC=CC=1)=O)CC)C(=O)C1=NC=CC=C1O YVMBAUWDIGJRNY-BESUKNQGSA-N 0.000 abstract 1
- RLNUPSVMIYRZSM-UHFFFAOYSA-N Pristinamycin Natural products CC1OC(=O)C(C=2C=CC=CC=2)NC(=O)C2CC(=O)CCN2C(=O)C(CC=2C=CC(=CC=2)N(C)C)CCN(C)C(=O)C2CCCN2C(=O)C(CC)NC(=O)C1NC(=O)C1=NC=CC=C1O RLNUPSVMIYRZSM-UHFFFAOYSA-N 0.000 abstract 1
- 108010079780 Pristinamycin Proteins 0.000 abstract 1
- -1 alkenyl radical Chemical class 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052801 chlorine Chemical group 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- QUPDWYMUPZLYJZ-UHFFFAOYSA-N ethyl Chemical group C[CH2] QUPDWYMUPZLYJZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 229960003961 pristinamycin Drugs 0.000 abstract 1
- DAIKHDNSXMZDCU-OUDXUNEISA-N pristinamycin-IIA Natural products CC(C)[C@H]1OC(=O)C2=CCCN2C(=O)c3coc(CC(=O)C[C@H](O)C=C(C)C=CCNC(=O)C=C[C@@H]1C)n3 DAIKHDNSXMZDCU-OUDXUNEISA-N 0.000 abstract 1
- JOOMGSFOCRDAHL-XKCHLWDXSA-N pristinamycin-IIB Natural products CC(C)[C@@H]1OC(=O)[C@H]2CCCN2C(=O)c3coc(CC(=O)C[C@@H](O)C=C(C)C=CCNC(=O)C=C[C@H]1C)n3 JOOMGSFOCRDAHL-XKCHLWDXSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invencion describe derivados de estreptogramina de formula general (I): en la cual el radical R1 representa un radical metilo o etilo, el radical R2 representa un átomo de cloro o de bromo, o un radical alquenilo que contiene de 3 a 5 átomos de carbono cuando R3 y R4 son metilo, y uno de R3 y R4 es unátomo de hidrogeno o un radical metilo, y el otro es un radical metilo. Los derivados de estreptogramina de formula general (1) son particularmente interesantes por su actividad antibacteriana, eventualmente en asociacion con un derivado de pristinamicina II.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9409563A FR2723372B1 (fr) | 1994-08-02 | 1994-08-02 | Nouveaux derives de streptogramine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| PCT/FR1995/001025 WO1996004299A1 (fr) | 1994-08-02 | 1995-07-31 | Derives de streptogramine, leur preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9700712A true MX9700712A (es) | 1997-05-31 |
Family
ID=9465983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9700712A MX9700712A (es) | 1994-08-02 | 1995-07-31 | Derivados de estreptogramina, su preparacion y las composiciones farmaceuticas que los contienen. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5786449A (es) |
| EP (1) | EP0772630B1 (es) |
| JP (2) | JP3775686B2 (es) |
| KR (1) | KR970704463A (es) |
| AT (1) | ATE205853T1 (es) |
| AU (1) | AU696226B2 (es) |
| BR (1) | BR9508793A (es) |
| CA (1) | CA2196102A1 (es) |
| CZ (1) | CZ284383B6 (es) |
| DE (1) | DE69522810T2 (es) |
| DK (1) | DK0772630T3 (es) |
| ES (1) | ES2162932T3 (es) |
| FR (1) | FR2723372B1 (es) |
| GR (1) | GR3036908T3 (es) |
| MX (1) | MX9700712A (es) |
| NO (1) | NO970240D0 (es) |
| NZ (1) | NZ290436A (es) |
| PL (1) | PL318435A1 (es) |
| PT (1) | PT772630E (es) |
| SK (1) | SK14297A3 (es) |
| WO (1) | WO1996004299A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2775288B1 (fr) * | 1998-02-26 | 2000-03-31 | Rhone Poulenc Rorer Sa | Derives de streptogramines, leur preparation et les compositons qui les contiennent |
| FR2796949B1 (fr) * | 1999-07-27 | 2001-09-21 | Aventis Pharma Sa | Derives de streptogramines, leur preparation et les compositions qui les contiennent |
| FR2796950B1 (fr) * | 1999-07-27 | 2001-09-21 | Aventis Pharma Sa | Derives de streptogramines, leur preparation et les compositions qui les contiennent |
| DE60006130D1 (de) * | 1999-07-27 | 2003-11-27 | Aventis Pharma Sa | Streptograminderivate, ihre herstellung und sie enthaltende zubereitungen |
| CA3070851A1 (en) * | 2017-08-01 | 2019-02-07 | The Regents Of The University Of California | Methods of making streptogramin compositions and the use thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2549062B1 (fr) * | 1983-07-13 | 1985-10-25 | Rhone Poulenc Sante | Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent |
-
1994
- 1994-08-02 FR FR9409563A patent/FR2723372B1/fr not_active Expired - Fee Related
-
1995
- 1995-07-31 AU AU31173/95A patent/AU696226B2/en not_active Ceased
- 1995-07-31 MX MX9700712A patent/MX9700712A/es unknown
- 1995-07-31 US US08/776,665 patent/US5786449A/en not_active Expired - Lifetime
- 1995-07-31 BR BR9508793A patent/BR9508793A/pt not_active Application Discontinuation
- 1995-07-31 KR KR1019970700653A patent/KR970704463A/ko not_active Withdrawn
- 1995-07-31 PL PL95318435A patent/PL318435A1/xx unknown
- 1995-07-31 ES ES95926995T patent/ES2162932T3/es not_active Expired - Lifetime
- 1995-07-31 CA CA002196102A patent/CA2196102A1/fr not_active Abandoned
- 1995-07-31 PT PT95926995T patent/PT772630E/pt unknown
- 1995-07-31 WO PCT/FR1995/001025 patent/WO1996004299A1/fr not_active Ceased
- 1995-07-31 SK SK142-97A patent/SK14297A3/sk unknown
- 1995-07-31 JP JP50625496A patent/JP3775686B2/ja not_active Expired - Fee Related
- 1995-07-31 DE DE69522810T patent/DE69522810T2/de not_active Expired - Lifetime
- 1995-07-31 NZ NZ290436A patent/NZ290436A/en unknown
- 1995-07-31 CZ CZ97300A patent/CZ284383B6/cs not_active IP Right Cessation
- 1995-07-31 DK DK95926995T patent/DK0772630T3/da active
- 1995-07-31 EP EP95926995A patent/EP0772630B1/fr not_active Expired - Lifetime
- 1995-07-31 AT AT95926995T patent/ATE205853T1/de not_active IP Right Cessation
-
1997
- 1997-01-20 NO NO970240A patent/NO970240D0/no unknown
-
2001
- 2001-10-17 GR GR20010400675T patent/GR3036908T3/el not_active IP Right Cessation
-
2005
- 2005-05-20 JP JP2005148164A patent/JP4277015B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CZ30097A3 (en) | 1997-05-14 |
| JP3775686B2 (ja) | 2006-05-17 |
| JPH10503510A (ja) | 1998-03-31 |
| EP0772630A1 (fr) | 1997-05-14 |
| CA2196102A1 (fr) | 1996-02-15 |
| DK0772630T3 (da) | 2001-11-26 |
| AU696226B2 (en) | 1998-09-03 |
| ATE205853T1 (de) | 2001-10-15 |
| NO970240L (no) | 1997-01-20 |
| GR3036908T3 (en) | 2002-01-31 |
| ES2162932T3 (es) | 2002-01-16 |
| NZ290436A (en) | 1998-07-28 |
| SK14297A3 (en) | 1997-08-06 |
| KR970704463A (ko) | 1997-09-06 |
| JP4277015B2 (ja) | 2009-06-10 |
| NO970240D0 (no) | 1997-01-20 |
| FR2723372B1 (fr) | 1996-10-04 |
| PT772630E (pt) | 2002-02-28 |
| WO1996004299A1 (fr) | 1996-02-15 |
| DE69522810T2 (de) | 2002-04-04 |
| CZ284383B6 (cs) | 1998-11-11 |
| US5786449A (en) | 1998-07-28 |
| AU3117395A (en) | 1996-03-04 |
| EP0772630B1 (fr) | 2001-09-19 |
| FR2723372A1 (fr) | 1996-02-09 |
| PL318435A1 (en) | 1997-06-09 |
| BR9508793A (pt) | 1997-12-23 |
| JP2005290012A (ja) | 2005-10-20 |
| DE69522810D1 (de) | 2001-10-25 |
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