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MX9605400A - Tetrapeptidos novedosos, su preparacion y uso. - Google Patents

Tetrapeptidos novedosos, su preparacion y uso.

Info

Publication number
MX9605400A
MX9605400A MX9605400A MX9605400A MX9605400A MX 9605400 A MX9605400 A MX 9605400A MX 9605400 A MX9605400 A MX 9605400A MX 9605400 A MX9605400 A MX 9605400A MX 9605400 A MX9605400 A MX 9605400A
Authority
MX
Mexico
Prior art keywords
manufacture
compounds
tetrapeptides
novel
novel tetrapeptides
Prior art date
Application number
MX9605400A
Other languages
English (en)
Inventor
Wilhelm Amberg
Harald Bernard
Ernst Buschmann
Andreas Haupt
Lothar Janitschke
Bernd Janssen
Ulrich Karl
Andreas Kling
Stefan Muller
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of MX9605400A publication Critical patent/MX9605400A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Se describen compuestos de la formula (Ver Formula) en donde R1, R2, R3 y R4 tienen el significado señalado en al descripcion, y un proceso para prepararlos. Los compuestos son adecuados como material de partida para sintetizar substancias que son activas contra tumores.
MX9605400A 1994-05-06 1995-04-26 Tetrapeptidos novedosos, su preparacion y uso. MX9605400A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4415998A DE4415998A1 (de) 1994-05-06 1994-05-06 Neue Tetrapeptide, ihre Herstellung Verwendung
PCT/EP1995/001576 WO1995030690A1 (de) 1994-05-06 1995-04-26 Neue tetrapeptide, ihre herstellung und verwendung

Publications (1)

Publication Number Publication Date
MX9605400A true MX9605400A (es) 1997-12-31

Family

ID=6517454

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9605400A MX9605400A (es) 1994-05-06 1995-04-26 Tetrapeptidos novedosos, su preparacion y uso.

Country Status (13)

Country Link
US (2) US5886147A (es)
EP (1) EP0804466B1 (es)
JP (1) JP4452329B2 (es)
KR (1) KR970702879A (es)
AT (1) ATE174035T1 (es)
AU (1) AU2408295A (es)
CA (1) CA2189691C (es)
DE (2) DE4415998A1 (es)
ES (1) ES2126279T3 (es)
FI (1) FI119641B (es)
HU (1) HU220862B1 (es)
MX (1) MX9605400A (es)
WO (1) WO1995030690A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010009901A1 (en) 1996-12-11 2001-07-26 Basf Aktiengesellschaft Germany Antineoplastic peptides
TW474946B (en) * 1995-12-15 2002-02-01 Basf Ag Novel compounds, the preparation and use thereof
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US6203412B1 (en) * 1999-11-19 2001-03-20 Chartered Semiconductor Manufacturing Ltd. Submerge chemical-mechanical polishing
KR20020066476A (ko) * 2001-02-12 2002-08-19 쥬가이 세이야쿠 가부시키가이샤 펩타이드 유도체의 제조방법
KR20130009760A (ko) 2010-02-10 2013-01-23 이뮤노젠 아이엔씨 Ｃｄ２０ 항체 및 이의 용도

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4978744A (en) * 1989-01-27 1990-12-18 Arizona Board Of Regents Synthesis of dolastatin 10
US4879278A (en) * 1989-05-16 1989-11-07 Arizona Board Of Regents Isolation and structural elucidation of the cytostatic linear depsipeptide dolastatin 15
JP3523253B2 (ja) * 1992-05-20 2004-04-26 アボット ゲーエムベーハー ウント カンパニー カーゲー ドラスタチン誘導体
DE4415997A1 (de) * 1994-05-06 1995-11-09 Basf Ag Neuer peptidischer Wirkstoff und dessen Herstellung

Also Published As

Publication number Publication date
DE4415998A1 (de) 1995-11-09
WO1995030690A1 (de) 1995-11-16
AU2408295A (en) 1995-11-29
JP4452329B2 (ja) 2010-04-21
ES2126279T3 (es) 1999-03-16
CA2189691C (en) 2011-02-15
HUT75709A (en) 1997-05-28
US5886147A (en) 1999-03-23
DE59504450D1 (de) 1999-01-14
ATE174035T1 (de) 1998-12-15
CA2189691A1 (en) 1995-11-16
EP0804466A1 (de) 1997-11-05
HU9603068D0 (en) 1997-01-28
FI119641B (fi) 2009-01-30
KR970702879A (ko) 1997-06-10
FI964446L (fi) 1997-01-03
US6248865B1 (en) 2001-06-19
FI964446A0 (fi) 1996-11-05
EP0804466B1 (de) 1998-12-02
JPH09512802A (ja) 1997-12-22
HU220862B1 (en) 2002-06-29

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