[go: up one dir, main page]

MX9605371A - Derivados de purin-6-ona y procedimiento para su produccion. - Google Patents

Derivados de purin-6-ona y procedimiento para su produccion.

Info

Publication number
MX9605371A
MX9605371A MX9605371A MX9605371A MX9605371A MX 9605371 A MX9605371 A MX 9605371A MX 9605371 A MX9605371 A MX 9605371A MX 9605371 A MX9605371 A MX 9605371A MX 9605371 A MX9605371 A MX 9605371A
Authority
MX
Mexico
Prior art keywords
purin
derivatives
production
diseases
acilating
Prior art date
Application number
MX9605371A
Other languages
English (en)
Inventor
Ulrich Niewolhner
Erwin Bischoff
Joachim Hutter
Elisabeth Perzborn
Helmut Schutz
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MX9605371A publication Critical patent/MX9605371A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Los derivados de purin-6-ona se obtienen al acilar imidazol-carboxamidas sustituidas y ciclar a continuacion para obtener las purinas. Los derivados de purin-6-ona son adecuados como sustancia activa en medicamentos especialmente para el tratamiento de enfermedades cardiovasculares, enfermedades de los vasos sanguíneos periféricos así como del sistema urogenital.
MX9605371A 1995-11-06 1996-11-05 Derivados de purin-6-ona y procedimiento para su produccion. MX9605371A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19541264A DE19541264A1 (de) 1995-11-06 1995-11-06 Purin-6-on-derivate

Publications (1)

Publication Number Publication Date
MX9605371A true MX9605371A (es) 1997-05-31

Family

ID=7776713

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9605371A MX9605371A (es) 1995-11-06 1996-11-05 Derivados de purin-6-ona y procedimiento para su produccion.

Country Status (23)

Country Link
US (1) US5861396A (es)
EP (1) EP0771799A1 (es)
JP (1) JPH09124648A (es)
KR (1) KR970027082A (es)
AR (1) AR004545A1 (es)
AU (1) AU720305B2 (es)
BR (1) BR9605434A (es)
CA (1) CA2189401A1 (es)
CO (1) CO4770977A1 (es)
CZ (1) CZ325096A3 (es)
DE (1) DE19541264A1 (es)
EE (1) EE9600172A (es)
HU (1) HU217691B (es)
IL (1) IL119559A0 (es)
MX (1) MX9605371A (es)
NO (1) NO964667L (es)
NZ (1) NZ299683A (es)
PL (1) PL316816A1 (es)
SG (1) SG64953A1 (es)
SK (1) SK142596A3 (es)
TR (1) TR199600883A2 (es)
TW (1) TW360656B (es)
ZA (1) ZA969278B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1688599A (en) * 1998-01-05 1999-07-26 Eisai Co. Ltd. Purine derivatives and adenosine a2 receptor antagonists serving as preventives/remedies for diabetes
DE19838705A1 (de) * 1998-08-26 2000-03-02 Bayer Ag Neue Dihydro-(1,2,3)-triazolo-[4,5-d]pyrimidin-7-one
GB9828340D0 (en) * 1998-12-22 1999-02-17 Novartis Ag Organic compounds
US20050070499A1 (en) * 1999-11-08 2005-03-31 Pfizer Inc. Compounds for the treatment of female sexual dysfunction
IL139457A0 (en) 1999-11-08 2001-11-25 Pfizer Compounds for the treatment of female sexual dysfunction
WO2002009713A2 (de) * 2000-08-01 2002-02-07 Bayer Aktiengesellschaft Selektive pde 2-inhibitoren als arzneimittel zur verbesserung der wahrnehmung
US20020065286A1 (en) * 2000-08-21 2002-05-30 Davies Michael John Treatment of wounds
US7501409B2 (en) * 2000-09-06 2009-03-10 Mitsubishi Tanabe Pharma Corporation Preparations for oral administration
DE10064105A1 (de) 2000-12-21 2002-06-27 Bayer Ag Neue Substituierte Imidazotriazinone
US7927623B2 (en) * 2001-02-15 2011-04-19 Mitsubishi Tanabe Pharma Corporation Tablets quickly disintegrated in oral cavity
EA005974B1 (ru) 2001-02-23 2005-08-25 Мерк Энд Ко., Инк. N-замещенные неарильные гетероциклические антагонисты nmda/nr2b
US6479493B1 (en) 2001-08-23 2002-11-12 Cell Pathways, Inc. Methods for treatment of type I diabetes
PL370599A1 (en) 2001-11-02 2005-05-30 Pfizer Products Inc. Treatment of insulin resistance syndrome and type 2 diabetes with pde9 inhibitors
HRP20050848A2 (en) * 2003-03-04 2006-06-30 Altana Pharma Ag Purin-6-one-derivatives
US20040220186A1 (en) * 2003-04-30 2004-11-04 Pfizer Inc. PDE9 inhibitors for treating type 2 diabetes,metabolic syndrome, and cardiovascular disease
GB0314054D0 (en) * 2003-06-17 2003-07-23 Pfizer Ltd Amide derivatives as selective serotonin re-uptake inhibitors
US20050054688A1 (en) * 2003-08-08 2005-03-10 Pfizer Inc Selective serotonin reuptake inhibitors in the treatment of disease
JP2007504117A (ja) * 2003-08-28 2007-03-01 アルタナ　ファルマ　アクチエンゲゼルシャフト 肺サーファクタントとｐｄｅ２阻害剤とを含有する組成物
US7291640B2 (en) * 2003-09-22 2007-11-06 Pfizer Inc. Substituted triazole derivatives as oxytocin antagonists
GB0409744D0 (en) * 2004-04-30 2004-06-09 Pfizer Ltd Novel compounds
JP2008533193A (ja) * 2005-03-21 2008-08-21 ファイザー・リミテッド オキシトシン拮抗薬としての置換トリアゾール誘導体
ES2313626T3 (es) * 2005-03-21 2009-03-01 Pfizer Limited Derivados de triazol sustituidos como antagonistas de oxitocina.
WO2007017752A1 (en) * 2005-08-10 2007-02-15 Pfizer Limited Substituted triazole derivatives as oxytocin antagonists
JP6696904B2 (ja) 2014-01-08 2020-05-20 イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． 製剤および医薬組成物
WO2016090380A1 (en) 2014-12-06 2016-06-09 Intra-Cellular Therapies, Inc. Organic compounds
HK1244427A1 (zh) 2014-12-06 2018-08-10 Intra-Cellular Therapies, Inc. 有机化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4451478A (en) * 1982-03-12 1984-05-29 Newport Pharmaceuticals International, Inc. Imidazole compounds
IL76546A (en) * 1984-10-12 1988-12-30 Warner Lambert Co 9-(heteroarylalkyl)-6-purine(thi)one derivatives,their preparation and pharmaceutical compositions containing them
WO1988003923A1 (fr) * 1986-11-25 1988-06-02 Institut Organicheskogo Sinteza Akademii Nauk Latv Guanines substitutees en position 9
IT1241452B (it) * 1990-06-28 1994-01-17 Sigma Tau Ind Farmaceuti Derivati oligopeptidici dell'ipoxantina dotati di attivita' immunomodulante e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
BR9605434A (pt) 1998-08-04
TR199600883A2 (tr) 1997-05-21
HUP9603071A2 (en) 1997-05-28
NO964667D0 (no) 1996-11-05
US5861396A (en) 1999-01-19
NZ299683A (en) 1998-09-24
JPH09124648A (ja) 1997-05-13
HU9603071D0 (en) 1996-12-30
AR004545A1 (es) 1998-12-16
CO4770977A1 (es) 1999-04-30
EE9600172A (et) 1997-06-16
EP0771799A1 (de) 1997-05-07
ZA969278B (en) 1997-06-02
TW360656B (en) 1999-06-11
SG64953A1 (en) 1999-05-25
IL119559A0 (en) 1997-02-18
NO964667L (no) 1997-05-07
HU217691B (hu) 2000-03-28
CZ325096A3 (en) 1997-06-11
AU720305B2 (en) 2000-05-25
SK142596A3 (en) 1997-05-07
AU7053296A (en) 1997-05-15
KR970027082A (ko) 1997-06-24
PL316816A1 (en) 1997-05-12
HUP9603071A3 (en) 1998-04-28
CA2189401A1 (en) 1997-05-07
DE19541264A1 (de) 1997-05-07

Similar Documents

Publication Publication Date Title
MX9605371A (es) Derivados de purin-6-ona y procedimiento para su produccion.
IL131450A0 (en) 1,5-Dihydro-pyrazolo [3,4-d]-pyrimidinone derivatives
ZA975866B (en) Novel heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases.
MX9601399A (es) Benzociclopentano oxazolidinonas que contienen heteroatomos, procedimiento para su produccion y medicamentos que los contienen.
HU9802224D0 (en) Pyrazol derivatives, process for producing them and their use as medicament
GR3036279T3 (en) Utilization of benzazols as UV-absorbers, new benzazoles and process for their preparation.
BG100293A (en) 2,8-disubstituted quinazolinons
HU9600680D0 (en) Benzazepine,-benzoxazepine- and benzothiazepine-n-acetic acid derivatives, process for producing them, and pharmaceutical composition containing them
CA2268394A1 (en) New heterocyclylmethyl-substituted pyrazol derivates
HUT49789A (en) Fungicides containing as active substance derivatives of quinoline, quinazolin or zinnoline and process for production of the active substance
ZA965752B (en) Triphenylethylenes, process for their production, pharmaceutical preparations that contain these triphenylethylenes as well as their use for the production of pharmaceutical agents.
NO305868B1 (no) Alginat-oligosakkarid, framgangsmÕte for framstilling av alginat-oligosakkarid i blodtrykksendende nµringsmiddel
HUP9601358A3 (en) Fluoro-phenyl-substituted alkenyl-carboxylic-guanidines, process for producing them, their use as medicines or diagnostica, and pharmaceutical compositions containing them
WO2000008007A3 (de) Cyclopentabenzofuran-derivate und ihre verwendung
PL308074A1 (en) Derivatives of borone peptides, their production as well as their application in medical therapy
MY113431A (en) Substituted benzenesulfonylureas and -thioureas, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
MY130107A (en) Piperidylmethyl-substituted chroman derivatives
HU9201799D0 (en) New 2-amino-5-ciano-1,4-dihydropiridine-derivatives, process for their use and their use as medicaments
HUT46659A (en) Process for producing pyrrolidine-2-(1,3-dicarbonyl) derivatives and pharmaceuticals comprising the same as active ingredient
EP0267297A4 (en) SIALOSYLCHOLESTEROL, PROCESS FOR THE PREPARATION AND MEDICINE AGAINST DISORDERS OF THE NERVOUS SYSTEM.
AU3806285A (en) Hydantoin derivatives, process for producing the same and medicine containing the same.
ZA898775B (en) Cyclopropyl-substituted azolylmethylcarbinols,processes for their preparation and their use as medicaments
ZA969319B (en) Derivatives of imidazole n-benzyldioxole, their preparation process, their use as medicaments, pharmaceutical composition and new use.
HRP960063B1 (en) Substituted benzenesulfonylureas and -thioureas, process for their preparation and their use in the production of pharmaceutical preparations as well as pharmaceutical preparations containing them
KR987000980A (en) Hydantoin derivatives, process for producing the same and herbicides comprising the same as active ingredients