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MX9603092A - Nuevos compuestos con efecto analgesico y anestesico local. - Google Patents

Nuevos compuestos con efecto analgesico y anestesico local.

Info

Publication number
MX9603092A
MX9603092A MX9603092A MX9603092A MX9603092A MX 9603092 A MX9603092 A MX 9603092A MX 9603092 A MX9603092 A MX 9603092A MX 9603092 A MX9603092 A MX 9603092A MX 9603092 A MX9603092 A MX 9603092A
Authority
MX
Mexico
Prior art keywords
local anesthetic
analgesic effect
new compounds
compounds
new
Prior art date
Application number
MX9603092A
Other languages
English (en)
Inventor
Anna-Lena Ask
Lars-Inge Olsson
Rune Sandberg
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of MX9603092A publication Critical patent/MX9603092A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Finger-Pressure Massage (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Se describen los nuevos compuestos de la formula (A), un proceso para su preparacion y su uso en la fabricacion de preparaciones farmacéuticas. Los nuevos compuestos tiene ambos, efecto anestésico local y analgésico.
MX9603092A 1994-02-11 1995-02-03 Nuevos compuestos con efecto analgesico y anestesico local. MX9603092A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9400447A SE9400447D0 (sv) 1994-02-11 1994-02-11 New compounds
PCT/SE1995/000106 WO1995021821A1 (en) 1994-02-11 1995-02-03 New compounds with analgesic and local anaesthetic effect

Publications (1)

Publication Number Publication Date
MX9603092A true MX9603092A (es) 1997-03-29

Family

ID=20392881

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9603092A MX9603092A (es) 1994-02-11 1995-02-03 Nuevos compuestos con efecto analgesico y anestesico local.

Country Status (31)

Country Link
US (2) US5756520A (es)
EP (1) EP0743940B1 (es)
JP (1) JPH09508904A (es)
CN (1) CN1067989C (es)
AT (1) ATE192435T1 (es)
AU (1) AU686760B2 (es)
BR (1) BR9506748A (es)
CA (1) CA2181068A1 (es)
CZ (1) CZ286753B6 (es)
DE (1) DE69516671T2 (es)
DK (1) DK0743940T3 (es)
EE (1) EE03252B1 (es)
ES (1) ES2148493T3 (es)
FI (1) FI963128A7 (es)
GR (1) GR3033999T3 (es)
HR (1) HRP950414B1 (es)
HU (1) HU216734B (es)
IL (1) IL112374A (es)
IS (1) IS1771B (es)
MX (1) MX9603092A (es)
MY (1) MY130166A (es)
NO (1) NO306718B1 (es)
NZ (1) NZ281355A (es)
PL (1) PL180212B1 (es)
PT (1) PT743940E (es)
RU (1) RU2145599C1 (es)
SE (1) SE9400447D0 (es)
SK (1) SK281931B6 (es)
TW (1) TW348176B (es)
WO (1) WO1995021821A1 (es)
ZA (1) ZA95709B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9523526D0 (en) * 1995-11-17 1996-01-17 Zeneca Ltd Therapeutic compounds
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
DE19912889A1 (de) * 1999-03-23 2000-09-28 Daimler Chrysler Ag Verfahren zur Herstellung eines Ventilsitzes
CA2509711A1 (en) * 2002-12-13 2004-07-01 Smithkline Beecham Corporation Piperidine derivatives as ccr5 antagonists
US6916833B2 (en) * 2003-03-13 2005-07-12 Hoffmann-La Roche Inc. Substituted piperidines
FR2861074B1 (fr) * 2003-10-17 2006-04-07 Sanofi Synthelabo Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique
WO2008045564A2 (en) * 2006-10-12 2008-04-17 Epix Delaware, Inc. Carboxamide compounds and their use as antagonists of the chemokine ccr2 receptor
BRPI0820701A2 (pt) 2007-12-11 2015-06-16 Cytopathfinder Inc Composto de carboxamida e seu uso como agonistas do receptor de quimiocina
US8473062B2 (en) 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US9320908B2 (en) * 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
US8494641B2 (en) * 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
US20100185249A1 (en) * 2009-01-22 2010-07-22 Wingeier Brett M Method and Devices for Adrenal Stimulation
EP3914246A1 (en) 2019-01-22 2021-12-01 ICM (Institut du Cerveau et de la Moelle Épinière) Local anesthetic for the treatment of neurological symptoms resulting from brain dysfunctions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2951080A (en) * 1957-08-05 1960-08-30 Lilly Co Eli Novel phenyl-substituted piperidines
NL130088C (es) * 1960-03-14
US3850935A (en) * 1971-10-16 1974-11-26 Sumitomo Chemical Co Process for producing piperidine derivatives by degrading quaternary piperidinium salts
US4369184A (en) * 1980-01-24 1983-01-18 Janssen Pharmaceutica N.V. 1-(Cyclohexyl)-4-aryl-4-piperidinecarboxylic acid derivatives
SE8904298D0 (sv) * 1989-12-21 1989-12-21 Astra Ab New compounds
JPH08504435A (ja) * 1992-12-14 1996-05-14 メルク シヤープ エンド ドーム リミテツド タキキニン受容体拮抗剤としての４−アミノメチル／チオメチル／スルホニルメチル−４−フェニルピペリジン

Also Published As

Publication number Publication date
CZ286753B6 (en) 2000-06-14
IL112374A (en) 1999-12-31
CN1140448A (zh) 1997-01-15
SK281931B6 (sk) 2001-09-11
PL180212B1 (pl) 2001-01-31
NO306718B1 (no) 1999-12-13
MY130166A (en) 2007-06-29
PL315777A1 (en) 1996-12-09
EE03252B1 (et) 2000-02-15
CN1067989C (zh) 2001-07-04
AU686760B2 (en) 1998-02-12
NO963292D0 (no) 1996-08-07
FI963128L (fi) 1996-08-09
WO1995021821A1 (en) 1995-08-17
EP0743940B1 (en) 2000-05-03
HU9602206D0 (en) 1996-10-28
GR3033999T3 (en) 2000-11-30
FI963128A0 (fi) 1996-08-09
CA2181068A1 (en) 1995-08-17
NZ281355A (en) 1998-02-26
SE9400447D0 (sv) 1994-02-11
JPH09508904A (ja) 1997-09-09
HUT75641A (en) 1997-05-28
US5968953A (en) 1999-10-19
DE69516671D1 (de) 2000-06-08
PT743940E (pt) 2000-08-31
HRP950414A2 (en) 1997-10-31
HU216734B (hu) 1999-08-30
SK92896A3 (en) 1997-07-09
CZ203296A3 (en) 1996-12-11
AU1826995A (en) 1995-08-29
NO963292L (no) 1996-08-07
RU2145599C1 (ru) 2000-02-20
DK0743940T3 (da) 2000-08-14
DE69516671T2 (de) 2001-02-01
IS1771B (is) 2001-05-28
TW348176B (en) 1998-12-21
EP0743940A1 (en) 1996-11-27
FI963128A7 (fi) 1996-08-09
IL112374A0 (en) 1995-03-30
ZA95709B (en) 1995-08-11
IS4251A (is) 1995-08-12
BR9506748A (pt) 1997-09-16
US5756520A (en) 1998-05-26
HRP950414B1 (en) 2001-02-28
ES2148493T3 (es) 2000-10-16
ATE192435T1 (de) 2000-05-15

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