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MX9602028A - Proceso de preparacion de compuestos de silicio biologicamente activos. - Google Patents

Proceso de preparacion de compuestos de silicio biologicamente activos.

Info

Publication number
MX9602028A
MX9602028A MX9602028A MX9602028A MX9602028A MX 9602028 A MX9602028 A MX 9602028A MX 9602028 A MX9602028 A MX 9602028A MX 9602028 A MX9602028 A MX 9602028A MX 9602028 A MX9602028 A MX 9602028A
Authority
MX
Mexico
Prior art keywords
biologically active
active silicon
bonds
silicon compounds
hydrolysed
Prior art date
Application number
MX9602028A
Other languages
English (en)
Inventor
Marie Christine Seguin
Jean Gueyne
Jean-Francois Nicolay
Andre Franco
Original Assignee
Exsymol Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exsymol Sa filed Critical Exsymol Sa
Publication of MX9602028A publication Critical patent/MX9602028A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0834—Compounds having one or more O-Si linkage
    • C07F7/0836—Compounds with one or more Si-OH or Si-O-metal linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0834—Compounds having one or more O-Si linkage
    • C07F7/0838—Compounds with one or more Si-O-Si sequences
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0834—Compounds having one or more O-Si linkage
    • C07F7/0838—Compounds with one or more Si-O-Si sequences
    • C07F7/0872—Preparation and treatment thereof
    • C07F7/0874—Reactions involving a bond of the Si-O-Si linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896—Compounds having one or more Si-O-acyl linkages

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Silicon Polymers (AREA)

Abstract

Proceso de preparacion de compuestos de silicio biologicamente activos consistiendo de hidrolizar un precursor de formula: (ver formula); en la cual - A, B, C, D y X son radicales diferentes del OH, los enlaces A, B, C, D con el átomo Si siendo enlaces covalentes y 2 o 3 de estos enlaces son hidrolizables. La hidrolisis se hace en un solvente conteniendo una cantidad pequeña de agua en una proporcion con respecto al solvente comprendida de preferencia entre 0.1% y 5%, y al menos uno de los compuestos procediendo de enlaces hidrolizables de silicio es un compuesto dicho estabilizador impidiendo la formacion de polímeros a partir de enlaces hidrolizados del silicio.
MX9602028A 1994-09-30 1996-05-29 Proceso de preparacion de compuestos de silicio biologicamente activos. MX9602028A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9412089A FR2725208B1 (fr) 1994-09-30 1994-09-30 Procede de preparation de composes de silicium biologiquement actifs sous forme concentree

Publications (1)

Publication Number Publication Date
MX9602028A true MX9602028A (es) 1998-01-31

Family

ID=9467729

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9602028A MX9602028A (es) 1994-09-30 1996-05-29 Proceso de preparacion de compuestos de silicio biologicamente activos.

Country Status (16)

Country Link
US (1) US6172250B1 (es)
EP (1) EP0737199B1 (es)
JP (1) JP4194116B2 (es)
KR (1) KR100440423B1 (es)
CN (1) CN1136315A (es)
AU (1) AU702457B2 (es)
BR (1) BR9506388A (es)
CA (1) CA2176510C (es)
CZ (1) CZ296427B6 (es)
DE (1) DE69525444T2 (es)
ES (1) ES2171556T3 (es)
FR (1) FR2725208B1 (es)
HU (1) HU226009B1 (es)
MX (1) MX9602028A (es)
PT (1) PT737199E (es)
WO (1) WO1996010574A1 (es)

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* Cited by examiner, † Cited by third party
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FR2761075B1 (fr) * 1997-03-24 1999-06-11 Seguin Marie Christine Nouveaux composes a base de silicium biologiquement actifs et leurs applications therapeutiques
ES2147538B1 (es) * 1999-01-29 2001-04-01 Revlon Consumer Prod Corp Una locion capilar con propiedades mejoradas en su accion protectora del cabello y preventiva de su caida, y de reduccion de los efectos externos de la alopecia androgenetica y con ello de la caida del cabello.
CA2385915A1 (fr) * 1999-09-27 2001-04-05 L'oreal Composition cosmetique a base de composes organiques du silicium comportant au moins une fonction a effet cosmetique
US6953584B1 (en) 1999-09-27 2005-10-11 L'oreal Cosmetic compositions based on organic silicon compounds comprising at least a non basic solubilising function
JP3966726B2 (ja) 1999-09-27 2007-08-29 ロレアル 部分的に中和した有機ケイ素化合物をベースとする化粧品組成物
US7595308B2 (en) * 2002-11-18 2009-09-29 Grenpharma Llc Compositions for treating and/or preventing diseases characterized by the presence of metal ions
EP1583765A4 (en) * 2002-11-18 2008-03-26 Grenpharma Llc COMPOSITIONS FOR THE TREATMENT AND / OR PREVENTION OF DISEASES CHARACTERIZED BY THE PRESENCE OF METALLIC IONS
WO2004045552A2 (en) * 2002-11-18 2004-06-03 Grenpharma Llc Compositions for treating and/or preventing diseases characterized by the presence of metal ions
EP1626748B1 (en) * 2003-05-13 2012-07-11 Medtronic, Inc. Moisture curable materials for delivery of agents, methods, and medical devices
CA2586681A1 (en) * 2004-10-22 2006-05-04 Thomas C. Pochapsky Compositions for treating and/or preventing diseases characterized by the presence of the metal ions
RU2281169C1 (ru) 2004-12-06 2006-08-10 Закрытое акционерное общество "Научно-производственный внедренческий центр "Уральский научно-исследовательский и проектный институт обогащения и механической обработки полезных ископаемых - Техника" (ЗАО НПВЦ "Уралмеханобр - Техника") Флотационная колонная пневматическая машина
US8069270B1 (en) 2005-09-06 2011-11-29 Cisco Technology, Inc. Accelerated tape backup restoration
RU2382046C1 (ru) * 2008-08-13 2010-02-20 Институт органического синтеза им. И.Я. Постовского Уральского отделения Российской академии наук Водорастворимые кремнийорганические производные полиолов и гидрогели на их основе
US11407713B2 (en) 2011-01-03 2022-08-09 The William M. Yarbrough Foundation Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use
US9962361B2 (en) 2011-01-03 2018-05-08 The William M. Yarbrough Foundation Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use
US8933119B2 (en) 2011-01-03 2015-01-13 The William M. Yarbrough Foundation Method for treating phytophotodermatitis
US11279674B2 (en) 2011-01-03 2022-03-22 The William M. Yarbrough Foundation Isothiocyanate functional surfactant and associated method of use
US10647668B2 (en) 2011-01-03 2020-05-12 The William M. Yarbrough Foundation Isothiocyanate functional surfactant and associated method of use
US10308599B2 (en) 2011-01-03 2019-06-04 The William M. Yarbrough Foundation Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use
US10273205B2 (en) 2011-01-03 2019-04-30 The William M. Yarbrough Foundation Isothiocyanate functional surfactants, formulations incorporating isothiocyanate functional surfactants and associated methods for treating biofilms
US10640464B2 (en) 2011-01-03 2020-05-05 The William M. Yarbrough Foundation Use of isothiocyanate functional surfactants as Nrf2 inducers to treat epidermolysis bullosa simplex and related diseases
US8865765B2 (en) 2011-01-12 2014-10-21 The William M. Yarbrough Foundation Method for treating eczema
US9532969B2 (en) 2011-02-08 2017-01-03 The William M. Yarbrough Foundation Method for treating psoriasis
US10434082B2 (en) 2012-07-26 2019-10-08 The William M. Yarbrough Foundation Isothiocyanate functional compounds augmented with secondary antineoplastic medicaments and associated methods for treating neoplasms
US10080734B2 (en) 2012-07-26 2018-09-25 The William M. Yarbrough Foundation Method for treating autism and other neurodevelopmental disorders
US10335387B2 (en) 2012-07-26 2019-07-02 The William M. Yarbrough Foundation Method for treating infectious diseases with isothiocyanate functional compounds
US10441561B2 (en) 2012-07-26 2019-10-15 The William M. Yanbrough Foundation Method for treating benign prostatic hyperplasia (BPH), prostatitis, and prostate cancer
US9949943B2 (en) 2012-07-26 2018-04-24 The William M. Yarbrough Foundation Method for treating neurodegenerative diseases
US8865772B2 (en) 2012-07-26 2014-10-21 The William M. Yarbrough Foundation Method for treating skin cancer
US10434081B2 (en) 2012-07-26 2019-10-08 The William M. Yarbrough Foundation Inhibitors of macrophage migration inhibitory factor
US9839621B2 (en) 2012-07-26 2017-12-12 The William M. Yarbrough Foundation Method for treating bladder cancer
CN107428784B (zh) * 2014-12-02 2020-08-21 默沙东公司 用于制备4-((2s,5r)-6-(苄基氧基)-7-氧代-1,6-二氮杂双环[3.2.1]辛烷-2-甲酰胺基)哌啶-1-甲酸叔丁酯及其类似物的方法
FR3053249B1 (fr) 2016-07-02 2021-07-02 Estelle Piron Formulation cosmetique comprenant au moins une huile, une vitamine c et un silicium
BE1023898B1 (fr) 2016-08-25 2017-09-07 Sil'innov Scrl Composition comprenant du silicium et son procédé de préparation
FR3110573B1 (fr) * 2020-05-20 2024-01-19 Exsymol Sa Compositions comprenant des composés organo-silanols, et applications.
WO2025177801A1 (ja) * 2024-02-21 2025-08-28 三井化学株式会社 アスコルビン酸誘導体、重合開始用添加剤、重合開始剤、硬化性組成物調製用キット、硬化性組成物、硬化物、及び歯科材料

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BE559672A (es) * 1956-08-04
MC1067A1 (fr) * 1975-07-04 1976-05-21 C Gueyne Un procede de fabrication de silanols solubles dans l'eau biologiquement actifs
FR2610522B1 (fr) * 1987-02-06 1989-08-18 Gueyne Jean Produit therapeutique a base de derives organiques du silicium
FR2619113B2 (fr) * 1987-05-26 1991-06-28 Exsymol Sa Nouveaux produits de condensation de silanols, leurs preparation et application
FR2645863B1 (fr) * 1989-04-12 1994-09-23 Voisin Philippe Composes de silicium et procede de fabrication de ceux-ci
US5648511A (en) * 1990-11-19 1997-07-15 G.D. Searle & Co. Method for making intermediates useful in the synthesis of retroviral protease inhibitors
FR2725207B1 (fr) * 1994-09-30 1996-11-29 Exsymol Sa Composes a base de silicium biologiquement actifs, leurs applications therapeutiques et cosmetiques

Also Published As

Publication number Publication date
US6172250B1 (en) 2001-01-09
DE69525444T2 (de) 2002-10-10
CZ145896A3 (en) 1997-02-12
CA2176510C (fr) 2007-04-03
FR2725208B1 (fr) 1996-11-29
KR100440423B1 (ko) 2004-10-12
AU3611395A (en) 1996-04-26
AU702457B2 (en) 1999-02-25
CA2176510A1 (fr) 1996-04-11
CZ296427B6 (cs) 2006-03-15
PT737199E (pt) 2002-07-31
BR9506388A (pt) 1997-11-18
FR2725208A1 (fr) 1996-04-05
ES2171556T3 (es) 2002-09-16
WO1996010574A1 (fr) 1996-04-11
DE69525444D1 (de) 2002-03-21
JPH09505836A (ja) 1997-06-10
EP0737199A1 (fr) 1996-10-16
JP4194116B2 (ja) 2008-12-10
EP0737199B1 (fr) 2002-02-13
HU9601251D0 (en) 1996-07-29
HU226009B1 (en) 2008-02-28
CN1136315A (zh) 1996-11-20
HUT74604A (en) 1997-01-28

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